title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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White blood cell segmentation by color-space-based k-means clustering. | White blood cell (WBC) segmentation, which is important for cytometry, is a challenging issue because of the morphological diversity of WBCs and the complex and uncertain background of blood smear images. This paper proposes a novel method for the nucleus and cytoplasm segmentation of WBCs for cytometry. A color adjust... | 25,256,107 | [
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Optimization of an optical inspection system based on the Taguchi method for quantitative analysis of point-of-care testing. | This study presents an optical inspection system for detecting a commercial point-of-care testing product and a new detection model covering from qualitative to quantitative analysis. Human chorionic gonadotropin (hCG) strips (cut-off value of the hCG commercial product is 25 mIU/mL) were the detection target in our st... | 25,256,108 | [
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Incorporating a wheeled vehicle model in a new monocular visual odometry algorithm for dynamic outdoor environments. | This paper presents a monocular visual odometry algorithm that incorporates a wheeled vehicle model for ground vehicles. The main innovation of this algorithm is to use the single-track bicycle model to interpret the relationship between the yaw rate and side slip angle, which are the two most important parameters that... | 25,256,109 | [
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Blood lactate level and meconium aspiration syndrome. | Approximately 5% of infants born with a meconium-stained amniotic fluid (MSAF) develop meconium aspiration syndrome (MAS). Early recognition of infants at highest risk for the development of MAS and the prediction of disease severity are important for optimizing the clinical strategies for prevention and treatment. The... | 25,256,123 | [
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Heterogeneous symptom patterns of sexually abused children in treatment: understanding the complexity of the problem. | A major challenge for clinicians and researchers is the heterogeneity of the severity and type of symptoms presented by sexually abused youth, including those who are subclinical on traditional clinical measures but still present to treatment. Most research continues to treat sexually abused youth as a single populatio... | 25,256,140 | [
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Cardiovascular magnetic resonance for evaluation of heart involvement in ANCA-associated vasculitis. A luxury or a valuable diagnostic tool? | Antineutrophil cytoplasmic antibody (ANCA)-related vasculitis is a systemic small-vessel vasculitis, including 3 clinical syndromes: granulomatosis with polyangiitis, known as Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and the Churg-Strauss syndrome (CSS). ANCA-related vasculitis usually pre... | 25,256,145 | [
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Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type: longitudinal observation of radiographic findings in a child heterozygous for a KIF22 mutation. | Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type (SEMDJL2), is a rare disorder due to a KIF22 gene mutation and characterized by postnatal short stature, midface hypoplasia and generalized ligamentous laxity. Radiologic hallmark includes severe involvement of the epiphyses and the slender appearan... | 25,256,152 | [
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Radiation dose and image quality in pediatric chest CT: effects of iterative reconstruction in normal weight and overweight children. | New CT reconstruction techniques may help reduce the burden of ionizing radiation. To quantify radiation dose reduction when performing pediatric chest CT using a low-dose protocol and 50% adaptive statistical iterative reconstruction (ASIR) compared with age/gender-matched chest CT using a conventional dose protocol a... | 25,256,153 | [
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Effect of post-thaw addition of seminal plasma on motility, viability and chromatin integrity of cryopreserved donkey jack (Equus asinus) spermatozoa. | Pregnancy rates in donkeys after artificial insemination with cryopreserved semen are still low, compared to the horse species. Addition of autologous seminal plasma to frozen-thawed semen appeared to improve pregnancy rates. The aims of this study were to evaluate (1) sperm motility and plasma membrane integrity after... | 25,256,158 | [
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Patentability of self-replicating technologies. | Patents provide an incentive to inventors, investors, and entrepreneurs to conduct research and development, especially in risky (i.e., unpredictable) fields of technology. This review discusses whether self-replicating technologies are patentable within the United States and the issues surrounding them. Self-replicati... | 25,256,175 | [
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A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol. | Physical activity levels of Australia's ageing population are declining and coincidentally rates of overweight and obesity are increasing. Adequate levels of physical activity and a healthy diet are recognised as important lifestyle factors for the maintenance of a healthy weight and prevention of chronic diseases. Ret... | 25,256,185 | [
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Therapist-guided, Internet-based cognitive-behavioural therapy for body dysmorphic disorder (BDD-NET): a feasibility study. | Cognitive-behavioural therapy (CBT) is an effective treatment for body dysmorphic disorder (BDD). However, most sufferers do not have access to this treatment. One way to increase access to CBT is to administer treatment remotely via the Internet. This study piloted a novel therapist-supported, Internet-based CBT progr... | 25,256,187 | [
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First experience with the jailed pressure wire technique in the provisional side branch stenting of coronary bifurcation lesions. | The provisional strategy (PS) is an accepted modality of treatment in coronary bifurcation interventions, though, after main vessel (MV) stenting, the assessment of the side branch (SB) becomes more difficult. In bifurcation interventions, the major advantage of fractional flow reserve (FFR) is the avoidance of the nee... | 25,256,199 | [
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Breaking the Glass Ceiling: Increasing the Meaningful Involvement of Women Living With HIV/AIDS (MIWA) in the Design and Delivery of HIV/AIDS Services. | The meaningful involvement of women living with HIV/AIDS (MIWA) is a key feature of women-centred HIV care, yet little is known about transforming MIWA from principle to practice. Drawing on focus group data from the Canadian HIV Women's Sexual and Reproductive Health Cohort Study (CHIWOS), we explored HIV-positive wom... | 25,256,222 | [
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Dietary fatty acids and risk of coronary heart disease in men: the Kuopio Ischemic Heart Disease Risk Factor Study. | The epidemiological evidence of the role of dietary saturated fatty acids (SFA) in the development of coronary heart disease (CHD) is inconsistent. We investigated the associations of dietary fatty acids with the risk of CHD and carotid atherosclerosis in men with high SFA intake and high rates of CHD. In total, 1981 m... | 25,256,234 | [
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Controlling the misuse of cobalt in horses. | Cobalt is a well-established inducer of hypoxia-like responses, which can cause gene modulation at the hypoxia inducible factor pathway to induce erythropoietin transcription. Cobalt salts are orally active, inexpensive, and easily accessible. It is an attractive blood doping agent for enhancing aerobic performance. In... | 25,256,240 | [
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The neuroprotective role of vesicular monoamine transporter 2 in neurodegenerative diseases. | Neuropharmacological relation of religious belief supports the role of dopaminergic activation as the leading neurochemical feature. However, vesicular monoamine transporter-2 (VMAT-2) has been shown to be responsible for removing of neurotransmitters such as dopamine that may secondarily lead to a neuroprotective acti... | 25,256,242 | [
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[Epidemiology of bacillary pulmonary tuberculosis according to HIV status of patients followed in the department of infectious diseases Conakry (Guinea)]. | Despite many efforts of prevention and the availability of free treatment, TB/HIV co-infection is still rampant in Guinea. The objective of this study was to describe the epidemiology of smear positive pulmonary tuberculosis according to HIV status among patients hospitalized in the infectious diseases department of Co... | 25,256,251 | [
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Children and young adults with CF in the USA have better lung function compared with the UK. | People with cystic fibrosis (CF) are managed differently in the USA and UK providing an opportunity to learn from differences in practice patterns. To compare cross-sectional demographics, practice patterns and clinical outcomes between US and UK CF patients. This was a cross-sectional study using 2010 data from patien... | 25,256,255 | [
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Structural connectivity of the salience-executive loop in schizophrenia. | Previously, differences have been shown in effective connectivity of the salience network between healthy controls and patients with schizophrenia. Specifically, the right anterior insula (rAI) fails to modulate the dorsolateral prefrontal cortex (DLPFC). In 35 controls and 31 patients with schizophrenia, we extended t... | 25,256,265 | [
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Wound Documentation by Using 3G Mobile as Acquisition Terminal: An Appropriate Proposal for Community Wound Care. | The increasing numbers of cases of wound disease are now posing a big challenge in China. For more convenience of wound patients, wound management in community health care centers under the supervision of a specialist at general hospitals is an ideal solution. To ensure an accurate diagnosis in community health clinics... | 25,256,281 | [
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Conservative Surgery of Diabetic Forefoot Osteomyelitis: How Can I Operate on This Patient Without Amputation? | Surgery is necessary in many cases of diabetic foot osteomyelitis. The decision to undertake surgery should be based on the clinical presentation of diabetic foot osteomyelitis. Surgery is required when the bone is protruding through the ulcer, there is extensive bone destruction seen on x-ray or progressive bone damag... | 25,256,285 | [
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Chronic Ulceration and Sinus Formation due to Foreign Body: An Often-Forgotten Problem. | Foreign bodies like residues of suture or mesh may lead to a foreign body reaction, cavity formation and continuous secretion and perhaps ulceration. We present a more than 9 years long medical record of a 49 year old man after a simple surgical procedure. The background was a sinus formation generated from a foreign b... | 25,256,286 | [
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Syntactic complexity effects in sentence production. | Syntactic complexity effects have been investigated extensively with respect to comprehension (e.g., Demberg & Keller, 2008; Gibson, 1998, 2000; Gordon et al., 2001, 2004; Grodner & Gibson, 2005; King & Just, 1991; Lewis & Vasishth, 2005; Lewis et al., 2006; McElree et al., 2003; Wanner & Maratsos, ... | 25,256,303 | [
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The Effects of General Practitioners' Use of Argumentation to Support Their Treatment Advice: Results of an Experimental Study Using Video-Vignettes. | In recent years, general practice consultation has often been characterized as an argumentative activity. It has been argued that, guided by the ethical and legal principle of informed consent and the ideal standards of participatory and evidence-based medicine, doctors should provide argumentative support for their re... | 25,256,304 | [
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Patient selection for TAVI in 2014: is there a justification for treating low- or intermediate-risk patients? The surgeon's view. | The introduction of transcatheter aortic valve implantation (TAVI) has revolutionised the treatment of patients with symptomatic severe aortic valve stenosis (AS). In extreme and high-risk patients, randomised studies have shown the benefit of this new therapy. However, there are still a lot of unknowns, and the questi... | 25,256,322 | [
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Valve-in-valve apps: why and how they were developed and how to use them. | Rapid growth in transcatheter heart valve (THV) technology has led to its use in the treatment of degenerated bioprosthetic surgical heart valves (SHV) and failed mitral repairs. Multiple reports of valve-in-valve (VIV) and valve-in-ring (VIR) procedures have appeared in the literature during the last three years. The ... | 25,256,331 | [
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Transcription coactivator Arabidopsis ANGUSTIFOLIA3 modulates anthocyanin accumulation and light-induced root elongation through transrepression of Constitutive Photomorphogenic1. | ANGUSTIFOLIA3 (AN3), a transcription coactivator, is implicated in modulating cell proliferation. In this study, I found that AN3 is a novel regulator of anthocyanin biosynthesis and light-induced root elongation. Seedlings and seeds lacking AN3 activity presented significantly reduced anthocyanin accumulation and ligh... | 25,256,341 | [
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Raman spectroscopy of blood serum for Alzheimer's disease diagnostics: specificity relative to other types of dementia. | The key moment for efficiently and accurately diagnosing dementia occurs during the early stages. This is particularly true for Alzheimer's disease (AD). In this proof-of-concept study, we applied near infrared (NIR) Raman microspectroscopy of blood serum together with advanced multivariate statistics for the selective... | 25,256,347 | [
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Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism. | Nonalcoholic fatty liver disease (NAFLD) is a major health problem worldwide. Currently, there is a lack of conclusive information to clarify the molecular events and mechanisms responsible for the progression of NAFLD to fibrosis and cirrhosis and, more importantly, for differences in interindividual disease severity.... | 25,256,357 | [
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Critical assessment of models for transport of engineered nanoparticles in saturated porous media. | To reliably assess the fate of engineered nanoparticles (ENP) in soil, it is important to understand the performance of models employed to predict vertical ENP transport. We assess the ability of seven routinely employed particle transport models (PTMs) to simulate hyperexponential (HE), nonmonotonic (NM), linearly dec... | 25,256,358 | [
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Analysis of patient attrition in a publicly funded bariatric surgery program. | Obesity is a global epidemic, and several surgical programs have been created to combat this public health issue. Although demand for bariatric surgery has grown, so too has the attrition rate. In this study we identify patient characteristics and operational interventions that have contributed to high attrition in a m... | 25,256,371 | [
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Impact of crural relaxing incisions, Collis gastroplasty, and non-cross-linked human dermal mesh crural reinforcement on early hiatal hernia recurrence rates. | Hernia recurrence is the leading form of failure after antireflux surgery and may be secondary to unrecognized tension on the crural repair or from a foreshortened esophagus. Mesh reinforcement has proven beneficial for repair of hernias at other sites, but the use of mesh at the hiatus remains controversial. The aim o... | 25,256,373 | [
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Comment on Jameson et al.: Prevalence of antibodies against hantaviruses in serum and saliva of adults living or working on farms in Yorkshire, United Kingdom. | This British hantavirus IgG prevalence study, aimed at 119 asymptomatic farmers in England, and using indirect immunofluorescence assay (IFA) as screening technique, concluded that rat-transmitted Seoul virus (SEOV) might be the main suspect as hantaviral pathogen in the UK. Exactly the same conclusion, using the same ... | 25,256,389 | [
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Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. | Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists. Sequencing duration and costs are rapidly decreasing, sequencing hardware is under modification for use by non-experts, and software ... | 25,256,396 | [
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Curcumin inhibits cell growth and invasion through up-regulation of miR-7 in pancreatic cancer cells. | Accumulating evidence has revealed that a natural compound curcumin exerts its anti-tumor activity in pancreatic cancer. However, the underlying molecular mechanism remains elusive. Recently, miRNAs have been demonstrated to play a crucial role in tumorigenesis, suggesting that targeting miRNAs could be a promising app... | 25,256,401 | [
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Protein tyrosine phosphatase regulation of stem and progenitor cell biology. | This review surveys the contributions of protein tyrosine phosphatases (PTPs) to maintenance and differentiation of stem and progenitor cells. A diverse family of PTPs acts at multiple steps of signaling cascades and cellular locales. Their activities as signaling modifiers provide another layer of integration of signa... | 25,256,403 | [
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Synthesis and structures of bis-ligated zinc complexes supported by tridentate ketoimines that initiate L-lactide polymerization. | Eight bis-ligated, homoleptic, zinc complexes were synthesized through the reaction of NNO Schiff base ketoimines bearing varying substituents with diethyl zinc in an inert atmosphere glovebox at room temperature and isolated in 62-95% yield. The complexes were characterized with (1)H, (13)C, and (19)F nuclear magnetic... | 25,256,407 | [
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Standards of Scientific Conduct: Disciplinary Differences. | Teaching of responsible conduct of research is largely predicated on the assumption that there are accepted standards of conduct that can be taught. However there is little evidence of consensus in the scientific community about such standards, at least for the practices of authorship, collaboration, and data managemen... | 25,256,408 | [
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Vitamin D levels in an Australian population. | Levels of vitamin D in the population have come under increasing scrutiny, however there are only a few studies in Australia which measure levels in the general population. The aim of this study was to measure the levels of vitamin D within a large population cohort and examine the association with seasons and selected... | 25,256,413 | [
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Control of Glycosylation-Related Genes by DNA Methylation: the Intriguing Case of the B3GALT5 Gene and Its Distinct Promoters. | Glycosylation is a metabolic pathway consisting of the enzymatic modification of proteins and lipids through the stepwise addition of sugars that gives rise to glycoconjugates. To determine the full complement of glycoconjugates that cells produce (the glycome), a variety of genes are involved, many of which are regula... | 25,256,425 | [
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Recruitment and retention of home support workers in rural communities. | This qualitative study examined recruitment and retention of home support workers (HSWs) providing home support in rural communities. Thirty-two participants were recruited across four island-based communities located in British Columbia, Canada. Thematic analysis of interview data revealed several key themes: (a) how ... | 25,256,429 | [
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The Sexual Beliefs of Turkish Men: Comparing the Beliefs of Men With and Without Erectile Dysfunction. | Sexual beliefs underlying male sexual dysfunction are known to emphasize excessively high sexual performance, among other inaccuracies. The purpose of this study was to determine the frequency of certain sexual beliefs among Turkish men with and without erectile dysfunction. In this comparative-descriptive study, demog... | 25,256,444 | [
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Rare Late-Onset Presentation of Glutaric Aciduria Type I in a 16-Year-Old Woman with a Novel GCDH Mutation. | Glutaric acidemia type I (GA-I) is a treatable autosomal recessive disorder of lysine, hydroxylysine, and tryptophan metabolism caused by glutaryl-CoA dehydrogenase (GCDH) deficiency. Presentation and progression of disease are variable ranging from asymptomatic carrier state to catastrophic encephalopathy. GA-I usuall... | 25,256,449 | [
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Self-degradation of tissue adhesive based on oxidized dextran and poly-L-lysine. | We have developed a low-toxicity bioadhesive based on oxidized dextran and poly-L-lysine. Here, we report that the mechanical properties and degradation of this novel hydrogel bioadhesive can be controlled by changing the extent of oxidation of the dextran and the type or concentration of the anhydride species in the a... | 25,256,455 | [
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A specific immunological method to detect and quantify bacterial 2-substituted (1,3)-β-D-glucan. | Exopolysaccharides synthesized by lactic acid bacteria have prebiotic properties and contribute to the rheology and texture of fermented foods. Here, we have standardized an immunological method for the specific detection of 2-substituted (1,3)-β-D-glucans. The method allows direct detection and quantification of this ... | 25,256,456 | [
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Grafting of β-cyclodextrin to magnetic graphene oxide via ethylenediamine and application for Cr(VI) removal. | A novel β-cyclodextrin (β-CD) polymer adsorbent named β-cyclodextrin/ethylenediamine/magnetic graphene oxide (CD-E-MGO) was synthesized for decontamination of Cr(VI) from aqueous solution. The sorption kinetics, isotherms and thermodynamics, as well as the effects of pH, aniline and ionic strength on the sorption proce... | 25,256,471 | [
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Influence of sodium carboxymethylcellulose on the aggregation behavior of aqueous 1-hexadecyl-3-methylimidazolium chloride solutions. | The influence of sodium carboxymethylcellulose (NaCMC) on the aggregation phenomena of a surface active ionic liquid 1-hexadecyl-3-methylimidazolium chloride (C16MeImCl) was studied in aqueous solutions using electrical conductivity and surface tension measurements. The counterion condensation behavior of NaCMC (aq) an... | 25,256,477 | [
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Flexible, highly transparent and iridescent all-cellulose hybrid nanopaper with enhanced mechanical strength and writable surface. | With the development of flexible electronic devices, there is increasing requirement for the inexpensive and environmental-friendly substrates. Cellulose paper has gained great attention because of its abundance, biodegradability and renewability. In this paper, we designed a hybrid nanopaper by introducing native cell... | 25,256,484 | [
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Facile synthesis of acyl chitosan isothiocyanates and their application to porphyrin-appended chitosan derivative. | Chitosan (1) was reacted with phenylisothiocyanate in 5% AcOH/H2O to give N-phenylthiocarbamoyl chitosan (2) with a degree of substitution (DS) of N-phenylthiocarbamoyl groups of 0.86 in 87.1% yield. The following acylation of compound 2 with hexanoyl chloride in the presence of pyridine afforded 3,6-di-O-2,3-hexanoyl ... | 25,256,486 | [
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Production, purification and application of polysaccharide-based bioflocculant by Paenibacillus mucilaginosus. | The production and purification of polysaccharide-based bioflocculants (PSBs) by Paenibacillus mucilaginosus GIM1.16 in metal ion-supplemented medium and basal medium were evaluated. Three purified PSB1-1, PSB2-1 and PSB3-1 possessed different monosaccharide composition and their molecular weights were 2.53 × 10(6), 7.... | 25,256,508 | [
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Catalytic reduction of p-nitrophenol by using platinum nanoparticles stabilised by guar gum. | We report a facile and green method to synthesise highly stable dispersions of platinum nanoparticles (PtNPs) with an average particle size of ∼ 6 nm. Natural, nontoxic, eco-friendly biopolymer guar gum was utilised as both the reducing and capping agent precursor in aqueous medium. The PtNPs that had been stabilised b... | 25,256,515 | [
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MW-assisted synthesis of carboxymethyl tamarind kernel polysaccharide-g-polyacrylonitrile: optimization and characterization. | Microwave-assisted synthesis of graft copolymer of carboxymethyl tamarind seed polysaccharide and polyacrylonitrile was carried out. The effect of formulation and process variables on grafting efficiency of carboxymethyl tamarind kernel polysaccharide-g-poly(acrylonitrile) was studied using response surface methodology... | 25,256,516 | [
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Electrospinning an essential oil: cinnamaldehyde enhances the antimicrobial efficacy of chitosan/poly(ethylene oxide) nanofibers. | Due to the persistent spread of antibiotic resistance, commercial antibiotic treatments are proving ineffective. Cinnamaldehyde (CA), a volatile essential oil, eradicates pathogens non-specifically. However, the ability to incorporate essential oils into nanofiber mats has not yet been demonstrated, and, only six studi... | 25,256,519 | [
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Ultra-sensitive immunoassay biosensors using hybrid plasmonic-biosilica nanostructured materials. | We experimentally demonstrate an ultra-sensitive immunoassay biosensor using diatom biosilica with self-assembled plasmonic nanoparticles. As the nature-created photonic crystal structures, diatoms have been adopted to enhance surface plasmon resonances of metal nanoparticles on the surfaces of diatom frustules and to ... | 25,256,544 | [
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Five vacuolar Ca(2+) exchangers play different roles in calcineurin-dependent Ca(2+)/Mn(2+) tolerance, multistress responses and virulence of a filamentous entomopathogen. | Multiple Vcx1 (vacuolar calcium exchanger) paralogues exist in many filamentous fungi but are functionally unexplored unlike a single Vcx1 ortholog well characterized in yeasts. Here we show that five Vcx1 paralogues (Vcx1A-E) in Beauveria bassiana are conditionally functional for intracellular Ca(2+) homeostasis and c... | 25,256,588 | [
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Next-generation DNA sequencing of a Swedish malignant hyperthermia cohort. | Malignant hyperthermia (MH)-related mutations have been identified in the ryanodine receptor type 1 gene (RYR1) and in the dihydropyridine gene (CACNA1S), but about half of the patients do not have causative mutations in these genes. We wanted to study the contribution of other muscle genes to the RYR1 phenotypes. We d... | 25,256,590 | [
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Tubal ligation and salpingectomy and the risk of epithelial ovarian cancer and borderline ovarian tumors: a nationwide case-control study. | According to the recent theories on the ovarian cancer origin, any protective effect of tubal ligation may vary with histologic subtype of ovarian cancer. Furthermore, bilateral salpingectomy may represent an opportunity for surgical prevention of serous ovarian cancer. Nationwide register-based case-control study. Den... | 25,256,594 | [
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Sulfur-based composite cathode materials for high-energy rechargeable lithium batteries. | There is currently an urgent demand for highly efficient energy storage and conversion systems. Due to its high theoretical energy density, low cost, and environmental compatibility, the lithium sulfur (Li-S) battery has become a typical representative of the next generation of electrochemical power sources. Various ap... | 25,256,595 | [
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Contemporary management of symptomatic primary aortic mural thrombus. | Primary aortic mural thrombus (PAMT) is an uncommon condition but an important source of noncardiogenic emboli with a difficult diagnosis and a high rate of complications, including high mortality. We report our experience of thromboembolic disease from PAMT and review its contemporary management. Retrospective analysi... | 25,256,613 | [
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The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα. | Recently, the rationale for combining targeted therapy with immunotherapy has come to light, but our understanding of the immune response during MAPK pathway inhibitor treatment is limited. We discovered that the immune microenvironment can act as a source of resistance to MAPK pathway-targeted therapy, and moreover du... | 25,256,614 | [
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Ichthyosaurs from the French Rhaetian indicate a severe turnover across the Triassic-Jurassic boundary. | Mesozoic marine reptiles went through a severe turnover near the end of the Triassic. Notably, an important extinction event affected ichthyosaurs, sweeping a large part of the group. This crisis is, however, obscured by an extremely poor fossil record and is regarded as protracted over the entire Norian-earliest Juras... | 25,256,640 | [
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Prevalence and Correlates of Sexual Dysfunction in Men and Women With Type 2 Diabetes. | This study aimed to assess the prevalence and correlates of sexual dysfunction in a sample of Dutch men and women with type 2 diabetes. Patients with type 2 diabetes who were between the ages of 40 and 75 years from 4 Dutch diabetes centers were asked to complete self-report questionnaires covering sociodemographic cha... | 25,256,659 | [
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Pyrolysis technologies for municipal solid waste: a review. | Pyrolysis has been examined as an attractive alternative to incineration for municipal solid waste (MSW) disposal that allows energy and resource recovery; however, it has seldom been applied independently with the output of pyrolysis products as end products. This review addresses the state-of-the-art of MSW pyrolysis... | 25,256,662 | [
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Difference in adherence to and influencing factors of a healthy lifestyle between middle-aged and elderly people in Korea: A multilevel analysis. | Comprehensive research for factors related to healthy lifestyles of the elderly is limited. The present study aimed to elucidate the factors associated with adherence to a healthy lifestyle by age groups. The present study was based on data from the 2005 Korea National Health and Nutrition Examination Survey. We calcul... | 25,256,663 | [
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Autophagic LC3B overexpression correlates with malignant progression and predicts a poor prognosis in hepatocellular carcinoma. | Autophagy is a process that involves lysosomal degradations of cellular organelles and closely related to tumor occurrence and progression. However, its importance in hepatocellular carcinoma (HCC) was still controversial. Therefore, this study is aimed to address the clinicopathologic effect of microtubule-associated ... | 25,256,671 | [
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Red blood cell alloimmunization is influenced by recipient inflammatory state at time of transfusion in patients with sickle cell disease. | Sickle cell disease (SCD) patients are at increased risk of red blood cell (RBC) alloimmunization. Recipient inflammatory state at time of transfusion has been shown to regulate alloimmunization in murine models, but evidence is lacking in SCD patients. We retrospectively studied a cohort of alloimmunized SCD patients ... | 25,256,676 | [
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Diet composition transiently modulates proliferative and potency features of human cord blood-derived mesenchymal stem cells. | Mesenchymal stem cells (MSC) emerged in the last few years as a promise in regenerative medicine and have been actively tested in several clinical trials worldwide. However, the lack of common standards and a precise definition of MSC preparations remain a major obstacle in research and application. In this study, we c... | 25,256,683 | [
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A functional screen identifies miRs that induce radioresistance in glioblastomas. | The efficacy of radiotherapy in many tumor types is limited by normal tissue toxicity and by intrinsic or acquired radioresistance. Therefore, it is essential to understand the molecular network responsible for regulating radiosensitivity/resistance. Here, an unbiased functional screen identified four microRNAs (miR1, ... | 25,256,711 | [
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Flow-scanning optical tomography. | We present a 3D tomography technique for in vivo observation of microscopic samples. The method combines flow in a microfluidic channel, illumination through a slit aperture, and a Fourier lens for simultaneous acquisition of multiple perspective angles in the phase-space domain. The technique is non-invasive and natur... | 25,256,716 | [
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0.08444766,
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The RBMX gene as a candidate for the Shashi X-linked intellectual disability syndrome. | A novel X-linked intellectual disability (XLID) syndrome with moderate intellectual disability and distinguishing craniofacial dysmorphisms had been previously mapped to the Xq26-q27 interval. On whole exome sequencing in the large family originally reported with this disorder, we identified a 23 bp frameshift deletion... | 25,256,757 | [
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Neural control of the endocrine pancreas. | The autonomic nervous system affects glucose metabolism partly through its connection to the pancreatic islet. Since its discovery by Paul Langerhans, the precise innervation patterns of the islet has remained elusive, mainly because of technical limitations. Using 3-dimensional reconstructions of axonal terminal field... | 25,256,769 | [
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The impact of restraint reduction meetings on the use of restrictive physical interventions in English residential services for children and young people. | The aim was to examine the impact of post restraint reduction meetings upon the frequency and restrictiveness of restraint use in English children's residential services. Attention has been drawn to the misuse, overuse and safety of some techniques used to physically restrain children in residential services. Successfu... | 25,256,775 | [
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Gestational hypoxia and epigenetic programming of brain development disorders. | Adverse environmental conditions faced by an individual early during its life, such as gestational hypoxia, can have a profound influence on the risk of diseases, such as neurological disorders, in later life. Clinical and preclinical studies suggest that epigenetic programming of gene expression patterns in response t... | 25,256,780 | [
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The relationship between iron deficiency in patients with Helicobacter pylori-infected nodular gastritis and the serum prohepcidin level. | Helicobacter pylori (H. pylori) is recognized as a causative agent for unexplained iron-deficiency anemia (IDA). We evaluated many background factors influencing an iron-deficiency state in adult patients with various H. pylori-infected upper gastrointestinal tract diseases. Study 1: H. pylori-infected 121 patients (no... | 25,256,783 | [
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Focusing and continuous separation of microparticles by insulator-based dielectrophoresis (iDEP) in stair-shaped microchannel. | Focusing and separation of microparticles in a complex mixture have had wide applications in chemistry, biology, medicine, etc. This work presents a numerical and experimental investigation on focusing and continuous separation of microparticles in a geometrically optimized arrangement of steps in the form of a stairca... | 25,256,784 | [
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A small molecule inhibits protein disulfide isomerase and triggers the chemosensitization of cancer cells. | Resistance to chemotherapeutic agents represents a major challenge in cancer research. One approach to this problem is combination therapy, the application of a toxic chemotherapeutic drug together with a sensitizing compound that addresses the vulnerability of cancer cells to induce apoptosis. Here we report the disco... | 25,256,790 | [
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Bioscouring of cotton using lipase from marine bacteria Bacillus sonorensis. | Bioscouring refers to the enzymatic removal of impurities from cotton fabric, which imparts it with improved hydrophilicity for further wet processes. In the present study, the efficacy of lipase from newly isolated marine bacteria Bacillus sonorensis isolated from marine clams Paphia malabarica collected from Kalbadev... | 25,256,798 | [
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Tailoring of the dopamine coated surface with VEGF loaded heparin/poly-L-lysine particles for anticoagulation and accelerate in situ endothelialization. | Coronary artery disease is a great threat to human health and is the leading killer worldwide. Percutaneous coronary intervention is the most effective therapy; however, thrombus, and restenosis caused by endothelium injury continue to be problematic after treatment. It is widely accepted that surface biofunctional mod... | 25,256,819 | [
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Diagnostic value of aberrant gene methylation in stool samples for colorectal cancer or adenomas: a meta-analysis. | Many studies have reported detection of aberrant methylation of genes in stool sample for early colorectal cancer (CRC) or adenomas had high sensitivity and specificity, but still remained controversial. We aimed to evaluate the diagnostic value of stool testing for markers of CRC and adenomas. Medline, EMbase, Web of ... | 25,256,821 | [
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Terpenoids, flavonoids and caffeic acid derivatives from Salvia viridis L. cvar. Blue Jeans. | Three diterpenoids, 1-oxomicrostegiol (1), viroxocin (2), viridoquinone (3), were isolated from the roots of Salvia viridis L. cvar. Blue Jeans. Five known diterpenoids, microstegiol (4), 7α-acetoxy-14-hydroxy-8,13-abietadiene-11,12-dione (5; 7-O-acetylhorminone tautomer), 7α,14-dihydroxy-8,13-abietadiene-11,12-dione (... | 25,256,822 | [
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0.430636,
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Tension pneumothorax secondary to nasojejunal feeding tube misplacement in a mechanically ventilated dog. | An 11-year-old female terrier-cross underwent general anaesthesia and mechanical ventilation for insulinoma resection. Following tumour removal, three consecutive but unsuccessful attempts were made to place a wire-guided nasojejunal feeding tube (NJFT), using both nostrils, with one tube eventually left in situ in the... | 25,256,844 | [
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0.1019751,
0.1213682,
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Histopathological assessment of intrinsic laryngeal musculature in horses with dynamic laryngeal collapse. | The pathogenesis of bilateral dynamic laryngeal collapse associated with poll flexion (DLC) of horses is unknown but might be associated with intrinsic laryngeal muscle weakness. To investigate histopathological characteristics of the cricoarytenoideus dorsalis, the cricothyroid (CT) and the cricoarytenoideus lateralis... | 25,256,848 | [
0.0322871,
0.2093395,
0.2634864,
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0.124945,
0.4150715,
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Nitrate-induced biochemical and histopathological changes in the liver of rats: ameliorative effect of Hyparrhenia hirta. | The present study investigated the protective role of Hyparrhenia hirta (H. hirta) against sodium nitrate (NaNO3)-induced hepatoxicity. Male Wistar rats were randomly divided into three groups: a control group and two treated groups during 50 d with NaNO3 administered either alone in drinking water or co-administered w... | 25,256,859 | [
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... |
Both GPER and membrane oestrogen receptor-α activation protect ventricular remodelling in 17β oestradiol-treated ovariectomized infarcted rats. | Clinical and experimental studies have established that gender is a factor in the development of ventricular hypertrophy. We investigated whether the attenuated hypertrophic effect of oestradiol was via activation of phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) through non-genomic a... | 25,256,868 | [
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0.23395,
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0.30... |
Hemostatic abnormalities in young females with heavy menstrual bleeding. | To study the prevalence of hemostatic abnormalities, including bleeding disorders and risk factors, in young females referred to a multidisciplinary clinic for evaluation of heavy menstrual bleeding (HMB). Retrospective chart review was undertaken for 131 post-menarchal girls with HMB, 7 to 17 years of age, enrolled in... | 25,256,871 | [
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Laparoscopically assisted neovaginoplasty in vaginal agenesis: a long-term outcome study in 240 patients. | To assess the long-term outcome of an optimized minimally invasive neovaginoplasty technique in vaginal agenesis. Combined retrospective and prospective study. University hospital. 240 patients with congenital vaginal agenesis. Patients with an indication for neovagina creation underwent laparoscopically assisted neova... | 25,256,875 | [
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0.3293807,
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Ovarian teratoma with predominant hemangiomatous component in early childhood. | Ovarian teratoma with predominant hemangiomatous component in pediatric patients is very rare and its presentation may mimic that of malignancy. A 2-year-old girl presented with proptosis of the right eye. A right ovarian mass was detected on the physical examination. The right orbital lesion was consistent with venoly... | 25,256,876 | [
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Interhemispheric somatosensory differences in chronic pain reflect abnormality of the healthy side. | It is widely accepted that complex regional pain syndrome (CRPS) is associated with shrinkage of the primary somatosensory cortex (S1) representation of the affected limb. However, supporting evidence is surprisingly limited and may be compromised by high risk of bias. This study compared the S1 spatial representation ... | 25,256,887 | [
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0.3557849,
0.00890966,
... |
Commentary: Spinal instrumentation for mechanical radiculopathy secondary to lumbar metastases. | Moliterno J, Veselis CA, Hershey MA, et al. Improvement in pain after lumbar surgery in cancer patients with mechanical radiculopathy. Spine J 2014;14:2434-9 (in this issue). | 25,256,897 | [
0.1054175,
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The longer term experiences of parent training: a qualitative analysis. | Child conduct problems are a major public health priority. Group-based parenting programmes are popular in addressing such problems, but evidence for their longer-term effectiveness is limited. Moreover, process evaluations are rare and little is understood about the key facilitative and inhibitive factors associated w... | 25,256,901 | [
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0.2067972,
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0.1437411,
0.087589,
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Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania. | Abnormal skin findings are identified in over 90% of human immunodeficiency virus (HIV)-infected persons globally. A prospective cohort study of HIV-infected patients with skin complaints commencing antiretroviral therapy (ART) in northern Tanzania was undertaken. Consecutive HIV-infected subjects presenting with skin ... | 25,256,912 | [
0.1429314,
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0.2541384,
0.01366324,
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-... |
Antecedents to Psychological Reactance: The Impact of Threat, Message Frame, and Choice. | A 2 (Threat: high vs. low) × 2 (Frame: gain vs. loss) × 2 (Choice: yes vs. no) × 2 (Behavior: prevention vs. detection) factorial design Web-based experiment (N = 814) was conducted to investigate the impact of threat to freedom, message frame, and behavioral choice as antecedents to psychological reactance. The intert... | 25,256,920 | [
0.03012215,
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0.02282623,
0.2469133,
0.2412727,
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... |
Effects of obesity on body temperature in otherwise-healthy females when controlling hydration and heat production during exercise in the heat. | Previous studies investigating body temperature responses in obese individuals during exercise in the heat fail to control metabolic heat production or hydration status during exercise. To determine if there are differences in body temperature responses between obese and non-obese females when controlling metabolic hea... | 25,256,946 | [
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0.2052277,
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The extent of cultural variation between adjacent chimpanzee (Pan troglodytes verus) communities; a microecological approach. | Chimpanzees show cultural differences among populations across Africa but also between neighboring communities. The extent of these differences among neighbors, however, remains largely unknown. Comparing three neighboring chimpanzee community in the Taï National Park, Côte d'Ivoire, we found 27 putative cultural trait... | 25,256,960 | [
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The putative oligosaccharide translocase SypK connects biofilm formation with quorum signaling in Vibrio fischeri. | Quorum signaling (QS) describes how bacteria can use small signaling molecules (autoinducers) to coordinate group-level behaviors. In Vibrio fischeri, QS is achieved through a complex regulatory network that ultimately controls bioluminescence, motility, and host colonization. We conducted a genetic screen focused on q... | 25,257,018 | [
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0.3352248,
0.2972288,
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A multi-channel device for high-density target-selective stimulation and long-term monitoring of cells and subcellular features in C. elegans. | Selective cell ablation can be used to identify neuronal functions in multicellular model organisms such as Caenorhabditis elegans. The optogenetic tool KillerRed facilitates selective ablation by enabling light-activated damage of cell or subcellular components in a temporally and spatially precise manner. However, th... | 25,257,026 | [
0.2451361,
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0.09201433,
0.2511005,
0.2415974,
0.0275012,
... |
Biologic-free remission of established rheumatoid arthritis after discontinuation of abatacept: a prospective, multicentre, observational study in Japan. | The aim of this study was to determine whether biologic-free remission of RA is possible with discontinuation of abatacept. Japanese RA patients in 28-joint DAS with CRP (DAS28-CRP) remission (<2.3) after >2 years of abatacept treatment in a phase II study and its long-term extension entered this 52 week, multice... | 25,257,039 | [
0.1037712,
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0.1575727,
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... |
The achievement of a decentralized water management through stakeholder participation: an example from the Drôme River catchment area in France (1981-2008). | Different water Acts (e.g., the European Water Framework Directive) and stakeholders involved in aquatic affairs have promoted integrated river basin management over recent decades. However, few studies have provided feedback on these policies. The aim of the current article is to fill this gap by exploring how local n... | 25,257,044 | [
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Evaluation of association of maternal IL-10 polymorphisms with risk of preeclampsia by A meta-analysis. | Emerging evidence shows that interleukin (IL)-10 gene polymorphisms can regulate its expression level and thus influence person's susceptibility to preeclampsia. However, various published results were inconsistent. To explore the association between maternal IL-10 gene polymorphisms and preeclampsia, we performed a me... | 25,257,050 | [
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0.2370594,
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0.3632684,
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