title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Pertussis outbreak in Austin and Travis County, Texas, 1975. | An outbreak of bacteriologically proven pertussis occurred in Austin and Travis County, Texas, over a 7-month period in 1975. Eighty persons were cultured for pertussis in our laboratory. A total of 62% of specimens from 34 individuals with suspected pertussis was positive for Bordetella pertussis. Diagnosis of acute c... | 197,117 | [
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Micro-indirect hemagglutination test for detection of antibody against transmissible gastroenteritis virus of pigs. | A micro-indirect hemagglutination (IHA) test was developed for detecting antibody against transmissible gastroenteritis (TGE) virus of pigs. TGE virus propagated in swine kidney cell cultures was highly purified and concentrated by the combination of ammonium sulfate precipitation, treatment with fluorocarbon, and sucr... | 197,119 | [
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The mitogenic effect of the lymphocytosis promoting factor from Bordetella pertussis on human lymphocytes. | The purified lymphocytosis promoting factor (LPF) from Bordetella pertussis was found to be a potent mitogen for peripheral blood lymphocytes (PBL) from normal adults as well as for cord blood lymphocytes. Proliferation occurred in autologous plasma or fetal calf serum, regardless of previous exposure to pertussis infe... | 197,121 | [
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Stimulation of surfactant production by oxytocin-induced labor in the rabbit. | The respiratory distress syndrome is believed to be due to insufficient surfactant. It is known that there is a greater incidence of the respiratory distress syndrome among infants delivered by cesarean section before labor than among those delivered after labor at the same gestational age. The purpose of this study wa... | 197,122 | [
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Immune complexes in congenital and natal cytomegalovirus infections of man. | The occurrence of circulating immune complexes was investigated in 31 patients with cytomegalovirus infection (29 infected in utero and 2 with natal infection) and 34 uninfected controls. Anti-complementary activity above 1:20 occurred in 34% (29/86) of the sera tested from the infected group in contrast to 7.5% (3/40)... | 197,126 | [
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The interaction of heparin with an apoprotein of human very low density lipoprotein. | An arginine-rich apoprotein obtained from human triglyceride-rich lipoprotein was isolated on a heparin affinity column when either the aqueousor urea-soluble apoproteins were applied to the column. Of all the aqueous- or urea-soluble apoproteins, only this arginine-rich protein exhibited a binding affinity to heparin.... | 197,127 | [
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Human lung tissue and anaphylaxis. Evidence that cyclic nucleotides modulate the immunologic release of mediators through effects on microtubular assembly. | The addition of specific antigen to IgE-sensitized human lung tissue causes the secretion of the mediators histamine and slow-reacting substance of anaphylaxis. The mechanisms by which increased levels of cyclic AMP suppress and increased levels of cyclic GMP enhance this secretory process were studied. Colchicine, an ... | 197,128 | [
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Tc-99m methylene diphosphonate versus Tc-99m pyrophosphate: biologic and clinical comparison. | The biologic and imaging characteristics of Tc-99m MDP and Tc-99m PPi were compared in animals and patients using freeze-dried bone-imaging kits. Biodistribution data in rabbits showed Tc-99m MDP had slightly higher bone uptake, significantly lower blood levels, and faster urinary excretion compared with Tc-99m PPi. Du... | 197,133 | [
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Laser cytophotometric detection of variations in spatial distribution of concanavalin-A cell surface receptors following viral infection. | Human cells in culture (H.Ep. 2) were infected with herpes simplex virus type 2 at a multiplicity of infection (m.o.i.) of 3 for 3, 18 and 36 hr. Spatial redistribution of concanavalin (Con-A) cell surface receptor sites was detected by an indirect double-antibody (peroxidase-conjugated goat anti-rabbit to rabbit anti-... | 197,163 | [
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Lymphocytosis-promoting factor of Bordetella pertussis: isolation, characterization, and biological activity. | The leukocytosis and lymphocytosis-promoting factor (LPF) of Bordetella pertussis has been isolated in apparently pure form. LPF is a protein essentially free of lipid and carbohydrate with an estimated molecular weight of 67,000-73,600 daltons. Purified LPF induced both histamine sensitization and refractoriness to ep... | 197,175 | [
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Binding, internalization, and degradation of high density lipoprotein by cultured normal human fibroblasts. | Comparative studies were made of the metabolism of plasma high density lipoprotein (HDL) and low density lipoprotein (LDL) by cultured normal human fibroblasts. On a molar basis, the surface binding of (125)I-HDL was only slightly less than that of (125)I-LDL, whereas the rates of internalization and degradation of (12... | 197,183 | [
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Genetic control of radiation leukemia virus-induced tumorigenesis. I. Role of the major murine histocompatibility complex, H-2. | Resistance to radiation leukemia virus-induced leukemogenesis is associated with the H-2D region of the H-2 complex, or with closely linked loci. The H-2Dd allele confers resistance ot the disease, while the H-2D-Q and H-2Ds alleles are associated with susceptibility. It is not clear whether Ir genes, or an alternative... | 197,195 | [
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Mannosidosis: pathology of the nervous system. | In a girl with mannosidosis, who died at 3 1/2 years of age, histopathological and ultrastructural changes in the nervous system are described. A widespread neuronal storage evidenced by ballooning of the neuronal perikarya is the salient histological feature and the occurrence of electron-lucent storage vacuoloes in n... | 197,212 | [
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Polyamine metabolism I: Synthesis of dansyl derivatives of N-(monoaminoalkyl)- and N-(polyaminoalkyl)acetamides and elucidation in urine of a cancer patient. | The dansyl derivatives of N-(monoaminoalkyl)- and N-(polyaminoalkyl)acetamides were synthesized and unequivocally characterized. TLC of the dansyl derivatives obtained from human urine indicated the presence of N-[3-[(4-aminobutyl)amino]propyl]acetamide (N1-acetylspermidine, N-[4-[(3-aminopropyl)amino]butyl]acetamide (... | 197,226 | [
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Fulminant puerperal sepsis associated with aplastic anemia: the case for prophylactic antibiotic therapy. | Fulminant puerperal sepsis due to Clostridium perfringens occurred in a primiparous 19-year-old woman who developed aplastic anemia during pregnancy. Although the risk of infectious complications among pregnant women with compromised host defenses has not been accurately determined, it appears to be increased, particul... | 197,236 | [
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In vitro synthesis of a unique RNA species by a T particle of vesicular stomatitis virus. | A T particle of vesicular stomatitis virus, containing most of the L-gene region, has been isolated. In vitro, these T particles synthesize exclusively a small adenine-rich RNA that is complementary to the T-particle genome. Partial sequence analysis of this small RNA indicates that it is an RNA of unique sequence with... | 197,268 | [
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Analysis of polyoma virus DNA replicative intermediates by agarose gel electrophoresis. | Agarose gel electrophoresis has been used to fractionate polyoma virus DNA replicative intermediates (RI) according to maturity. Approximate electrophoretic mobility versus maturity relationships were obtained for both intact (supercoiled) and nicked (relaxed) RI. There was considerable overlap between the supercoiled ... | 197,274 | [
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Genetics of resistance to phosphonoacetic acid in strain KOS of herpes simplex virus type 1. | A DNA- temperature-sensitive mutant of herpes simplex virus type 1 exhibiting thermolabile DNA polymerase activity, tsD9, was shown to be resistant to phosphonoacetic acid (PAA) when plated at the permissive temperature. ts+ revertants of tsD9 were PAA sensitive and exhibited DNA polymerase activity intermediate betwee... | 197,275 | [
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Amebiasis. An increasing problem among homosexuals in New York City. | During a five-year period at The New York Hospital, Entamoeba histolytica was identified in the stools of 20 men who had not traveled outside the New York area. All of the patients were found subsequently to homosexual. During this same period amebiasis was diagnosed in 30 men who had traveled; only two were homosexual... | 197,276 | [
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Chronic otitis media and hearing loss in the Eskimo population of Canada. | Chronic otitis media and hearing loss is a major health problem today in the Canadian Eskimo. The subject is reviewed and the findings of projects and a survey that have been carried out recently are discussed. A modality of treatment is proposed which is based upon the findings of the projects, the survey and other in... | 197,359 | [
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[Specific surface factor of dust particles and preliminary selection of silica dusts]. | The results of particles analysis of three kinds of silica dust by means of miscroscopy and sedimentation in Andreasen's pipette served as a base for the determination of factor phi specific for particle surface. This factor is expressed as a ratio of the mean projected diameter (dp) to the aerodynamic diameter (d). Th... | 197,376 | [
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Methionine biosynthesis in Saccharomyces cerevisiae. II. Gene-enzyme relationships in the sulfate assimilation pathway. | In Saccharomyces cerevisiae, the products of eleven different genes are needed for a functional sulfate assimilation pathway. Only five enzymatic steps are known in this pathway. The study of the gene-enzyme relationships has shown that the enzymes catalysing two of these steps are probably heteropolymeric. Moreover, m... | 197,388 | [
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Mutants of Saccharomyces cerevisiae resistant to carbon catabolite repression. | Mutants with defective carbon catabolite repression have been isolated in the yeast Saccharomyces cerevisiae using a selective procedure. This was based on the fact that invertase is a glucose repressible cell wall enzyme which slowly hydrolyses raffinose to yield fructose and that the inhibitory effects of 2-deoxygluc... | 197,390 | [
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Isolation and characterization of yeast mutants defective in intermediary carbon metabolism and in carbon catabolite derepression. | Yeast mutants deficient in the constitutive ADHI (adc 1) were used for the isolation of mutants with deficiencies of the intermediary carbon metabolism, and of mutants defective in carbon catabolite derepression. Mutants were recognized by their inability to grow on YEP-glycerol and/or on ethanol synthetic complete med... | 197,391 | [
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Inhibition of rabbit skeletal muscle phosphorylase phosphatase by spermine. | The effect of three naturally occurring polyamines (putrescine, spermidine, and spermine) on the activity of rabbit skeletal muscle phosphorylase phosphatase was investigated. Only spermine significantly inhibited the enzyme. The mode of inhibition (ki value of 0.3 mM) of the phosphatase by spermine appears to be diffe... | 197,399 | [
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Immunological selection of tumour cells which have lost SV40 antigen expression. | In an already tumorigenic spontaneously transformed mouse cell, after further transformation by SV40, the virus-specific antigenic function becomes dominant. By transplantation into syngeneic mice SV40 antigen negative revertant tumour cells can be selected out. | 197,429 | [
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About the influence of halogenated pyrimidines on the in vivo-oncogenesis. | Reported are in vivo trials on Friend virus-leukemia (FVL), on methylcholanthren-induced fibrosarcomas of the mouse, and on amelanotic melanoma No. 3 of the Syrian hamster after treatment with halogenated pyrimidines, 5'-bromodeoxyuridine (BUDR) and 5'-iododeoxyuridine (IUDR) as to provoke genuine oncorna viruses. Till... | 197,439 | [
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Application of the radioreceptor assay for human chorionic gonadotropin in pregnancy testing and management of trophoblastic disease. | A commercially prepared radioreceptor assay (RRA) for human chorionic gonadotropin (hCG) has been evaluated as a pregnancy test and in a quantitative assay to follow patients with hydatidiform mole. The RRA demonstrated almost 100% agreement in comparison with radioimmunoassay (RIA) and urinary hCG tests. In the quanti... | 197,458 | [
-0.04414812,
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0.1273592,
0.05284773,
0.1133359,
... |
Effect of benzodiazepines on central serotonergic neuron systems. | Intracerebral (i.c.) injection of serotonin (5-HT) into mice induced head twitches in a dose-dependent manner at 10 min after injection. The head twitches induced by 5-HT (i.c.) were potentiated by the pretreatment of isocarboxazid (3 mg/kg i.p.), and inhibited by cyproheptadine (0.3 mg/kg i.p.), a 5-HT antagonist. Ben... | 197,556 | [
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0.1516877,
0.2382947,
0.1726188,
0.3076863,
... |
The effects of various protein synthesis inhibitors on the sleep-wake cycle of rats. | The present investigation sought to determine the effects of Anisomycin (A), Chloramphenicol (ChA), Vincristine (V), and Penicilline G on the sleep-wake cycle of rats. It was found that both high and low doses of anisomycin decreased rapid eye movement (REM) sleep, while only high doses of ChA and V produced such a dec... | 197,558 | [
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0.232001,
0.00892533,
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Biological damage in testis by iodine-125 in partially blocked thyroid of rats. | Degeneration of testis has been observed after administration of Iodine-125 in potassiumperchlorate treated rats. Histological damage is associated with loss of DNA, RNA, acid phosphatase, total adenosine triphosphatase (ATPase) and Na/K dependent ATPase. Iodine-125 induced atrophic testis shows higher content of sodiu... | 197,564 | [
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0.326003,
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... |
Glucose-6-phosphatase inactivation and peroxidation of phosphatidylcholine in microsomal membranes. | Peroxidation induced by ascorbate on phospholipids of isolated rat liver microsomes were accompanied by losses in glucose-6-phosphatase activity (EC 3.1.3.9.). The existence of marked differences in the degradation rate for each phospholipid suggests a relationship between the alteration of phosphatidylcholine containi... | 197,573 | [
-0.1736906,
0.07510561,
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0.1399712,
0.2645293,
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... |
Adenine and adenosine are toxic to human lymphoblast mutants defective in purine salvage enzymes. | Mutants deficient in adenosine kinase or adenine phosphoribosyltransferase activities were selected from the WI-L2 line of human lymphoblasts. The adenosine kinase-deficient mutant was still as sensitive as its parent to growth inhibition caused by adenosine deaminase was inhibited. Similarly, the adenine phosphoribosy... | 197,600 | [
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0.1384546,
0.5160164,
0.1514891,
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... |
[Surveillance of hypothyroidism treatment]. | The efficacy of substitution treatment in primary or secondary hypothyroidism is based on the diappearance of the clinical signs of the disease and the return of blood levels of thyroxine and TSH within normal limits. The dosage should be adapted to the age of the patient the duration of the course of the hypothyroidis... | 197,630 | [
-0.1496317,
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0.07557452,
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0.1231568,
0.2477921,
0.3113257,
-0.1177971,... |
[Hepatic and pancreatic tomometry. Radioanatomy and application to hepatic pathology]. | More than 250 hepatic and pancreatic tomometries were carried out on a first generation tomometer. Anatomical and tomometric correspondances carried out on the cadaver led to precise radiological anatomy of the abdomen. Tomometry either alone or carried out after impregnation of the liver parenchyma with an emusion of ... | 197,636 | [
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0.1147715,
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0.07225883,
0.2124999,
0.1738683,
0.160083,
0.02017175,
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0.... |
[Impact of immune disorders in digestive pathology]. | The digestive tract has a special immune system where predominate the secretory factors of IgA. The IgA secreted by the plasma cells of the digestive mucosa is dimeric and is poured into the intestinal lumen after being attached to a protein of epithelial orgin. These facts lead to defence reactions of a special type.... | 197,637 | [
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0.4222395,
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0.03067748,
0.1483423,
0.3098053,
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-0.0289... |
[Influence of dose-time relationship on the pathogenesis of peripheral neuropathy (author's transl)]. | The development of peripheral neuropathies of cranial nerves and of the brachial plexus following curative deoses of irradiation is closely related with the total applied, the number and size of the individual doses per fraction and the overall time. Additional important factors for the occurrence of these late complic... | 197,662 | [
-0.08351295,
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0.04634046,
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0.1672317,
0.09827787,
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0.3353885,
0.102378,
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0.1767354,
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0.1773994,
0.1192167,
0.01908776,
0.3551377,
0.387269,
0.2020478,
0.1278023,
0.0878... |
[Several virologic and biochemical aspects of vaccination with antipoliomyelitis vaccine. Characteristics of intracellular virus-specific structures]. | The data are presented concerning infectious potentials of subvirus particles isolated from cytoplasmic extracts of various organs of cotton rats and guinea pigs inoculated intramuscularly with purified and concentrated poliomyelitis virus type II. As described earlier, from various organs of the animals (the brain, sp... | 197,714 | [
0.01155336,
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0.09430786,
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0.2451331,
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0.3165241,
0.6705308,
0.2655001,
0.4236242,
0.0811330... |
Mechanism and control of fluid secretion. | Fluid secretion and reabsorption by a variety of plant and animal tissues appear to be accomplished by osmotic coupling between solute transport and water movement. The local osmosis model suggests that active accumulation of solutes within narrow folds at the cell surface may produce the local gradients that generate ... | 197,717 | [
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0.1255597,
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0.06137687,
0.1031457,
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0.5047525,
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... |
[Malignant mixed tumor of the liver in an adult (author's transl)]. | A malignant mixed tumor of the liver was observed in a 55 years old woman. The tumor was composed of an adenocarcinoma, a haemangioendothe liosarcoma, and a chondrosarcoma. | 197,744 | [
-0.2071894,
0.06824724,
-0.1657001,
0.08162045,
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0.189102,
0.2493263,
0.5103402,
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... |
[Immunological characteristics of the 2-stage method of smallpox vaccination]. | As a result of observations carried out on children the authors present immunological characteristics of two-stage smallpox vaccination at different intervals (1 to 60 days) between the injection of inactivated and live vaccine. There proved to be acceleration and intensification of antibody formation after two-stage i... | 197,750 | [
-0.06479,
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0.2572604,
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0.2627008,
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0.08422781,
0.450837,
0.5548841,
0.1764462,
-0.2779304,
-0.0... |
[Obtaining group-specific fluorescent immunoglobulin for diagnosis of adenovirus infection]. | The authors present the results of a comparative study of several schemes of rabbit immunization with mixtures consisting of 4 and 7 (mixture No. 1) nad 2, 4, and 7 (mixture No. 2) adenovirus types for the purpose of obtaining group-specific fluorescent immunoglobulins. Since a direct correlative dependence of the acti... | 197,755 | [
-0.09995857,
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0.1365332,
0.1281779,
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0.04616772,
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0.5032863,
0.5207208,
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0.08444711,
... |
[Pathogenesis of creatinuria and aminoaciduria in neuromuscular diseases]. | By introducing inhibitors of phosphodiestherase and adenylacyclase the authors studied the role of cyclic AMP in the pathogenesis of creatinuria and aminoaciduria in neuro-muscular diseases. It was demonstrated that in patients with Duchenne myopathy creatinuria and aminoaciduria were possibly due to a deop of nucleoti... | 197,760 | [
-0.3946623,
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0.1641851,
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0.1067157,
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0.2016398,
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0.09285895,
0.3830096,
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... |
Oculodentodigital dysplasia syndrome. Report of four cases. | Four cases of oculodentodigital dysplasia are reported. Three cases are from the same family, father and two daughers. These three cases have the characteristics typical of this disorder: narrow nose, hypoplastic alae nasi, microphthalmia, defects of the teeth, syndactylyl of the IV and V fingers, and skeletal anomalie... | 197,779 | [
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0.08037655,
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0.2253173,
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0.2736148,
0.1724033,
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... |
Primary carcinoma of the liver. A histological study of 27 cases of primary carcinoma of the liver from Malawi. | Liver biopsies from 27 Bantu patients with primary carcinoma of the liver from Malawi were examined histologically. All the biopsies showed hepatocellular carcinoma (HCC). Structurally the tumours consisted of trabeculae or groups of such, separated by a variable amount of connective tissue which in a few cases was so ... | 197,780 | [
0.3158136,
0.2021761,
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0.01380581,
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0.114352,
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0... |
Cyclic AMP and Ca-binding in microsomal fractions isolated from rabbit colon smooth muscle. | From a homogenate of rabbit colon muscle two ATP dependent Ca-accumulating microsomal fractions were isolated by differential centrifugation on a sucrose density grandient at 35% and 35-45% sucrose. Adenylate cyclase and phosphodiesterase activities were found in the fractions. The Ca-accumulation and the ATPase activi... | 197,787 | [
0.09555516,
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0.59016,
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0.... |
Studies on the phosphodiesterase in various organs of rats and guinea-pigs of different ages and different sex. | The method of Butcher and Sutherland is used to determine the phosphodiesterase activity of various organ homogenates from rats and guinea-pigs of different age and sex. The different rat organs manifest great differences in their phosphodiesterase activity. Especially high phosphodiesterase activity is found in the ad... | 197,791 | [
0.01624079,
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0.2732621,
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... |
Effects of dexamethasone, desoxycorticosterone, and ACTH on serum concentrations of thyroxine, 3,5,3'-triiodothyronine and 3,3',5'-triiodothyronine. | The effects of a pure glucocorticoid, dexamethasone, and a pure mineralocorticoid, desoxycorticosterone, on the serum concentrations of thyroxine (T4), 3,5,3'-triiodothyronine (T3), and 3,3',5'-triiodothyronine (reverse T3, rT3) were compared both in healthy subjects and in athyreotic T4-substituted patients. In additi... | 197,800 | [
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0.03006177,
0.2162548,
0.4567824,
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0.... |
Neurologic manifestations in sarcoidosis: review of the literature, with a report of 23 cases. | Nervous system involvement by sarcoidosis has been considered rare, yet more than 400 cases have been reported. We present 23 additional cases here, including 14 with autopsies, and we review the literature. The overall frequency of neurologic involvement is 5%. Patients usually have other stigmata of sarcoidosis; howe... | 197,863 | [
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0.09137314,
0.03547517,
0.4196761,
-0.00854... |
The effect of a topical anesthetic on the recovery of Herpes simplex virus. | The effect of proparacaine hydrochloride (Ophthaine), a commonly used topical ocular anesthetic, on the recovery of types 1 and 2 herpes simplex virus (HSV) was studied in vitro and in vivo. In the in vitro studies, the titers of both virus types were significantly lower after exposing them to Ophthaine than after expo... | 197,867 | [
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0.3111751,
0.08840387,
0.1720794,
-0.1863977,
... |
Miscibility properties of binary phosphatidylcholine mixtures. A calorimetric study. | From data obtained by differential scanning calorimetry phase diagrams were constructed, using a thermodynamically based fitting method. The following binary mixtures of phosphatidylcholines in water were studied: 14:0/14:0-glycerophosphocholine/16:0/16:0-glucerophosphocholine, 14:0/14:0-glycerophosphocholine/18:0/18:0... | 198,000 | [
-0.2107937,
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-0.3898863,
-0.04915497,
-0.09529097,
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-0.2043832,
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0.5040078,
-0.3043859,
0.3176939,
0.2571261,
0.1951674,
0.0877118,
... |
[ESR study of the state of manganganese in chloroplasts]. | In chloroplasts isolated in tris-HCl buffer in the presence of 0.1 M NaCl or in the absence of salts an asymmetric ESR spectrum of Mn2+ was observed which differs in shape from the ESR spectrum of Mn2+ aquanions usually observed in chloroplasts treated with ultrasonics, reducer, 0.8 M tis-HCl buffer, pH 8. The transiti... | 198,017 | [
0.006603296,
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0.02784609,
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0.09455135,
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0.1333046,
-0.1047493,
-0.05848046,
0.522421,
0.1524479,
0.01474735... |
[Phosphoinositide content in the erythrocyte membranes of rats with spontaneous hypertension]. | The values of triphosphoinositides (TPI) and monophosphoinositides (MPI) contents per 1 mg of membrane protein in the erythrocyte hosts of spontaneously hypertensive rats (SHR) constitute 178 and 74%, respectively, of that in the erythrocyte hosts of normotensive rats (NR). The total amount of phosphoinositides in the ... | 198,041 | [
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0.2656739,
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0.1802174,
0.000021... |
Effect of isoprenaline and phenylephrine on the adenosine 3',5'-monophosphate content and mechanical activity of cold-stored and fresh taenia caecum from the guinea-pig. | 1. Cold storage treatment of the guinea-pig taenia caecum had a greater inhibitory effect on the isoprenaline-induced relaxation than that induced by phenylephrine. Prolonged cold storage (12-14 days) almost abolished the effect of isoprenaline but only reduced the phenylephrine effect. The ED50 of cyclic adenosine 3',... | 198,053 | [
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0.1415718,
0.1754509,
0.3615057,
-0.1168802,... |
Affinity chromatography of myosin, heavy meromyosin, and heavy meromyosin subfragment one on F-actin columns stabilized by phalloidin. | A method of affinity chromatography based on the trapping of actin filaments within agarose gel beads is described. This method can be used for the purification of myosin and its active proteolytic subfragments, as well as for studies on the interaction between actin and these proteins. Actin columns stabilized by phal... | 198,071 | [
-0.1301089,
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0.0196755,
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0.003722432,
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0.07922779,
0.8762984,
-0.135365,
-0.3748111,
0... |
Antibody responses in normal infants and in infants receiving chemotherapy for congenital neuroblastoma. | Three infants with congenital neuroblastoma received a primary series of diptheria-pertassis-tetanus (DPT) immunizations during and after courses of chemotherapy with immunosuppressive medications. Serum IgG, IgA and IgM levels and antidiphthria and antitetanus antibody responses were measured and compared with those o... | 198,094 | [
-0.1470593,
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0.192496,
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0.1161881,
0.4921669,
-0.1139085,
-0.2056601,
-... |
Preliminary clinical results from U.S. fast neutron teletherapy studies. | Over 700 patients with cancer have been treated with fast neutron beams since 1972 in three U.S. programs at the M.D. Anderson-TAMVEC (Houston and College Station, Texas), University of Washington (Seattle, Washington), and MANTA (Naval Research Laboratory, Washington, D.C.). Clinical applications are about to start at... | 198,095 | [
-0.2287229,
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0.005751053,
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-0.152455,
0.212016,
-0.01724345,
-0.2149422,
0... |
Histopathological study of the first Medical Research Council Nephroblastoma Trial. | A histological analysis of the tumors from the first Medical Research Council (M.R.C.) Nephroblastoma Trial was carried out. Material from 104 out of the 111 concluded cases was suitable for assessment. The degree of tubular differentiation and the presence or absence of glomeruli, cysts and papillary structures were c... | 198,098 | [
0.1171092,
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0.0260129,
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0.1648832,
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0.188671,
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0.2154544,
0.4127966,
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-0.1683262,
0.08... |
Inhibition of B-16 melanoma growth in vivo by a synthetic analog of prostaglandin E2. | The effect of systemic administration of 16,16-dimethyl prostaglandin E2-methyl ester (di-M-PGE2) on the growth of B-16 melanoma tumors has been studied in C57BL/6J mice. Daily i.p. injection of 5 mu of di-M-PGE2 commencing on the day of tumor inoculation with 10(5) and 10(6) viable cells delayed appearance of tumors; ... | 198,122 | [
-0.5319788,
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0.1270567,
0.1360659,
0.5970379,
0.5154842,
0.2094493,
-0.2564266,
... |
Fetal infection with bovine leukemia virus in sheep. | Several sheep fetuses were thymectomized, and their tails were removed at 58 to 65 days of gestation for tissue culture. Bovine leukemia virus (BLV) antigens were detected in serial culture of tissues from fetuses whose dams and sires were both BLV positive. However, no BLV antigens were detected in serial cultures of ... | 198,128 | [
0.0660546,
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0.1243719,
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0.00678876,
0.249744,
0.3186066,
-0.1352234,
-0.... |
[Changes in the blood cortisol levels during the first week of life in calves (Bos taurus) and lambs (Ovis aries)]. | At birth, the plasmatic level of cortisol is very variable and very high in the new-born Calf or the newborn Lamb. This level diminishes within one day and then varies between 10 and 30 ng/ml during the six following days. In the Calf, the secretion of cortisol can be directly stimulated by ACTH or inhibited at the lev... | 198,151 | [
0.0008372278,
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0.2050749,
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0.2316431,
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0.1722401,
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0.1810135,
0.172103,
0.2336177,
0.4379409,
0.1930745,
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... |
Studies on the metabolic defect in Broad-beta disease (hyperlipoproteinaemia type III). | The apoprotein composition of the main lipoprotein fractions (VLDL, LDL-1, LDL-2 and HDL) was studied initially in 15 patients with Broad-beta disease. Analytical isoelectric focusing of urea-soluble apo-VLDL and apo LSL-1 demonstrated a variant pattern of the polymorphic Apoprotein E with a deficient Apo E-III band in... | 198,168 | [
0.1683816,
0.04385507,
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0.03256474,
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0.162837,
0.1453684,
0.1018641,
0.1993592,
-0.1601038,
0.1... |
Effects of concurrent administration of lead, cadmium, and arsenic in the rat. | Humans are exposed to a number of toxic elements in the environment; however, most experiments with laboratory animals investigate only one toxic element. To determine if concomitant exposure to lead (Pb), cadmium (Cd), and/or arsenic (As) modified the changes produced by any one metal in various parameters of toxicity... | 198,203 | [
-0.04468049,
0.2282571,
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0.4193543,
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0.2341859,
0.42328,
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0.4154786,
-0.06120178,
0.20994... |
Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes. | Incubation of (3R,5S)-[5-3H1]mevalonate + (3RS)-[2-14C]mevalonate with Andrographis cell-free extract leads to trans,trans-farnesol and cis,trans-farnesol which both totally retain tritium. 2. This conflicts with our previous results which predict one third tritium loss in the cis,trans-farnesol. Inversion at C-1 durin... | 198,206 | [
-0.4280748,
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-0.4122692,
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0.3038047,
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0.002823822,
0.1878211,
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0.001496568,
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0.0005679486,
0.4976428,
0.4790682,
0.4094555,
-0.... |
Differential cytology of breast cancer. | The aim of the study was to investigate the possibility of predicting the histologic type of different breast cancers by semi-quantitative screening of cytologic criteria. Cytologic material was obtained by the aspiration technique. The frequency of ten cytologic criteria was correlated to five histologic types of brea... | 198,257 | [
-0.1027238,
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0.148725,
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0.06767315,
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0.1869808,
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0.4146802,
0.1051891,
-0.02729164,
... |
[Classification of strains of foot-and-mouth disease virus according to the relationship-dominance model for a better understanding of the concept of serologic and immunologic subtype]. | The homologous and heterologous serological titers of a specific serum can be integrated in a bidimensional system which characterizes the criteria of relationship and dominace. This bidimensional classification specifies more precisely the serological properties of each strain compared with the others (taxonomic purpo... | 198,287 | [
-0.1563985,
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0.2027184,
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0.1043045,
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0.01530231,
0.1033736,
0.006934517,
0.3672684,
0.1902141,
0.07134616,
-0.100599... |
[Methods of testing of safety of the anti-foot-and-mouth disease vaccine]. | Innocuity testing in bovines remains the reference method but other methods using mice and especially cell cultures may be employed. Different techniques (dialysis, neutralization, elution, etc.) allow the elimination of toxic constituents of the vaccine while respecting the eventual presence of small quantities of act... | 198,294 | [
-0.2809213,
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0.1454175,
0.1626225,
0.4045077,
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0.03048558,
0.1035557,
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0.6016725,
0.4114985,
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0.188... |
The use of suspension cultures for FMD vaccine production. Criteria for the evaluation of cells, virus and vaccine. | A survey of problems connected with the cell suspension culture for the production of FMD vaccine is presented, in order to stimulate a discussion. Introductory remarks are made on the following topics: 1) suspension cell lines used for FMD vaccine production, 2) terminology, 3) criteria for the characterization of a c... | 198,318 | [
-0.250304,
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0.2989435,
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0.1173427,
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0.1622003,
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0.2936731,
0.4371821,
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Gestational trophoblastic neoplasms: morphologic considerations. | Abnormal trophoblastic proliferation is the hallmark of a spectrum of lesions constituting the gestational trophoblastic neoplasms. Rapid proliferation, infiltration, vascular invasion, hematogenous dissemination, and spontaneous regression are features of both normal and neoplastic trophoblast. Trophoblastic hyperplas... | 198,349 | [
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0.02854568,
0.5105974,
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0.2687422,
0.1077772,
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0.23... |
Interferon inhibition of lymphocyte mitogenesis. | Interferon inhibits the early phase of mitogenic action of Concanavalin A on lymphocytes as measured by incorporation of labelled precursors in RNA, DNA or protein. There was no evidence for a role of cyclic AMP in the process of inhibition. Dialysis of interferon against high salt and urea did not separate cell inhibi... | 198,357 | [
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0.1371472,
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0.1236708,
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0.06593584,
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0.3188896,
0.2620763,
-0.2024689,
-0.1584895... |
Comparative pulmonary carcinogenicity of inhaled beta-emitting radionuclides in beagle dogs. | Beta-emitting radionuclides are important constituents of isotope inventories in light water reactors and may pose an inhalation hazard to industrial workers or the general population if they are released. To study the biological effects of such potential exposures, a series of life span studies was initiated in which ... | 198,366 | [
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0.3004245,
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0.1373357,
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0.2342531,
0.4285719,
0.1301439,
0.3944345,
0.5101061,
0.1052541,
... |
Characterization of SA12 as a simian virus 40-related papovavirus of chacma baboons. | SA12 virus, originally isolated from an uninoculated South African vervet monkey kidney culture, was identified as a new member of the simian virus 40 (SV40)-polyoma subgroup of papovaviruses. The virus produced a cytopathic effect with nuclear enlargement in primary rhesus kidney cells. The virion had papovavirus morp... | 198,375 | [
0.04355606,
0.1771389,
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0.2908733,
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0.05775593,
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0.02233176,
0.07830406,
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0.1618661,
0.02012156,
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... |
Epstein-Barr herpesvirus infection: inhibition by immunologically induced mediators with interferon-like properties. | When sensitized leukocytes were re-exposed to EBV antigen or to tuberculin-purified protein derivatives, they produced lymphokines, including the migration inhibition factor, which inhibited the migration of guinea-pig peritoneal exudate cells, and other lymphokines with the characteristics of interferon, which inhibit... | 198,380 | [
-0.2295884,
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0.06680927,
0.2597222,
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0.1192143,
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0.2189574,
-0.03183878,
0.003391146,
0.0351691... |
Cytochrome-linked respiration in host grown M. leprae isolated from an Armadillo (Dasypus novemcinctus, L.). | The bacilli were isolated from an armadillo (Dasypus novemcinctus, L.) and cytochrome systems as well as oxidation of succinate and NADH by M. leprae were studied. Cell-free extracts of M. leprae contained cytochromes of the a + a3, b, c and o type. Whole cell suspensions catalyzed the oxidation of succinate. The proce... | 198,384 | [
-0.1491314,
0.1521318,
0.207976,
0.1596617,
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0.09055524,
0.1670496,
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0.152... |
Purification and properties of poly(adenosine diphosphate ribose) synthetase. | Poly(ADP-ribose) synthetase has been purified approximately 5000-fold from rat liver nuclei. The activity of the purified enzyme is absolutely dependent upon the presence of native or synthetic DNA, and the further addition of histone(s) stimulates the activity 3- to 5-fold. When the ADP-ribosylated material synthesize... | 198,398 | [
0.1634073,
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0.3567194,
0.07346333,
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... |
Locomotory behavior, contact inhibition and pattern formation of 3T3 and polyoma virus-transformed 3T3 cells in culture. | The social behavior of 3T3 cells and their polynoma virus-transformed derivative (Py3T3 cells) was examined by time-lapse cinemicrography in order to determine what factors are responsible for the marked differences in the patterns formed by the two cell lines in culture. Contrary to expectations, both cell types have ... | 198,414 | [
-0.05663022,
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0.0270205,
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0.7042841,
0.05965463,
0.1201908,
0.05061774,... |
The variations of plasma corticosterone/cortisol ratios following ACTH stimulation or dexamethasone administration in normal men. | A radioimmunoassay for human plasma corticosterone has been developed. Plasma corticosterone increased 4.83 times as much as basal value at 60 min after an im injection of 0.25 mg synthetic beta1-24 ACTH (Cortrosyn) in normal subjects, whereas plasma cortisol increased 2.12 times as much at 60 min. And basal corticoste... | 198,428 | [
-0.1062425,
0.06869216,
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0.2145341,
0.02701768,
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0.02858868,
0.1139916,
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0.1922423,
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0.1642853,
0.1482087,
0.398051,
0.4887043,
0.1040057,
0.2353818,
-0.21... |
A hypothesis concerning the structure of cAMP-and cGMP-dependent protein kinases. | cAMP-and cGMP-dependent protein kinases have been purified. Each enzyme demonstrates high specificity and affinity for the cyclic nucleotide with binding of two moles of nucleotide per holoenzyme and each enzyme is an ATP: phosphotransferase. The holoenzymes have similar molecular weights and demonstrate similar molecu... | 198,441 | [
-0.1941314,
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0.3443848,
-0.03790908,
-0.2646998... |
Myocardial uptake of Tc-99m skeletal agents in the rat after experimental induction of microscopic foci of injury. | The cardiac uptake of Tc-99m tagged skeletal agents was studied after myocardial injury produced by subcutaneous catecholamine injection and random foot-shock stress. Rats stressed for 2 hr developed microfocal myocardial injury, without gross change, whereas those stressed for 12 hr sustained more confluent and someti... | 198,448 | [
-0.3600744,
0.1946185,
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0.21776,
0.3420525,
0.2294596,
-0.04180054,
0.001327... |
Cochlear micromechanics--a mechanism for transforming mechanical to neural tuning within the cochlea. | A linear mathematical model is proposed which will account for the differences observed between mechanically measured data of Rhode (1971) for basilar membrane motion, and the responses of neural tuning curves (Kiang et al., 1974). We show that theoretical tuning curves may be derived from mechanical responses by formi... | 198,449 | [
-0.2237879,
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0.1712999,
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0.2045991,
-0.1755254,
0.1164494... |
A rapid microassay for detecting antibodies against poliovirus based on [14C]thymidine uptake of treated cell cultures. | DNA synthesis of mammalian cells propagated in microplates can easily be measured if cell cultures incubated with [14C]thymidine are harvested on the glass fibre filters by a semiautomatic harvesting technique. Soon after infection with poliovirus, [14C]thymidine uptake of U cells (established, human amniotic cell line... | 198,477 | [
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0.439877,
0.6162878,
0.05833431,
-0.1448503,
-0.... |
An analysis of the actions of prostaglandin E1 on membrane currents and contraction in uterine smooth muscle. | 1. The effects of prostaglandin E(1) have been studied on the transmembrane potentials, ionic currents, and contractions in isolated myometrial strips from pregnant rats by means of a double sucrose gap apparatus.2. At low concentrations (10(-8) g/ml.), prostaglandin E(1) reduced the duration (though not the amplitude)... | 198,534 | [
-0.1713081,
0.04285223,
-0.1720783,
-0.03535414,
0.169499,
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0.1431951,
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0.159739,
0.06047859,
-0.07004976,
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-0.1033512,
0.07839528,
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-0.5937867,
0.01487918,
0.01412973,
0.06019497,
0.6079379,
0.3673478,
-0.0193388... |
11,12-secoprostaglandins. 4. 7-(N-alkylmethanesulfonamido) heptanoic acids. | A series of 7-(N-alkylmethanesulfonamido) heptanoic acids has been prepared which represents an extension of our 8-aza-11,12-secoprostaglandin studies. The studies. The compounds mimic the natural prostaglandins in that they markedly stimulate cAMP formation in the mouse ovary assay. | 198,546 | [
-0.2351517,
-0.02576089,
-0.2973611,
-0.06388994,
0.3871425,
0.1731399,
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0.02294422,
0.2657458,
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0.01453237,
0.03271823,
0.1564607,
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-0.7710323,
0.2299775,
-0.02459019,
0.1279539,
0.3651536,
0.001769212,
-0.178155... |
Cell proliferation and histologic classification of bronchogenic carcinoma. | The rate of cell proliferation of 99 bronchogenic carcinomas (94 primary tumors and 5 metastases) was evaluated from the labeling index after in vitro incorporation of [3H]thymidine; the rate was then correlated with the histologic tumor type according to the classification of the World Health Organization (WHO). Cell ... | 198,555 | [
-0.07930778,
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0.1786997,
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0.0573433,
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0.1809437,
0.02935025,
0.1645603,
0.4063222,
0.1367482,
-0.2542984,
... |
Characterization of a new type of human papillomavirus that causes skin warts. | A human papillomavirus (HPV) was isolated from the lesions of a patient (ML) bearing numerous hand common warts. This virus was compared with the well-characterized HPV found in typical plantar warts (plantar HPV). ML and plantar HPV DNAs have similar molecular weights (5.26 x 10(6) and 5.23 x 10(6), respectively) but ... | 198,572 | [
-0.01411006,
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0.1785166,
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0.09882515,
0.385633,
0.2231109,
0.1741969,
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-0.09161196,
0.1344079,
-0.02140222,
-0.02932143,
0.2035848,
0.07648452,
-0.07029... |
Human cytomegalovirus genome: partial denaturation map and organization of genome sequences. | Contour-length measurements of both nondenatured and partially denatured DNA from purified extracellular human cytomegalovirus indicate that more than one size class of viral DNA is encapsidated. In addition to a size class averaging about 100 x 10(6) daltons, a much less abundant class of larger viral DNA molecules, 1... | 198,578 | [
-0.30969,
0.2807078,
-0.2945242,
0.05385398,
0.2340234,
0.05823418,
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0.4224598,
0.04943844,
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0.1188366,
0.3731775,
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0.2742737,
0.01807132,
0.2239997,
0.4299928,
0.1437517,
-0.1138851,
0.0... |
Temperature-sensitive mutants of human cytomegalovirus. | Eight temperature-sensitive mutants of human cytomegalovirus have been isolated after mutagenesis with nitrosoguanidine. Three of these mutants have been classified into three separate complementation groups and are capable of synthesizing virus DNA at the nonpermissive temperature (39.5 degrees C). Two others appear u... | 198,584 | [
-0.2715194,
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-0.3450806,
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0.02141815,
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-0.08179374,
0.4622975,
0.3931331,
0.07487076,
0.04623019... |
Wilms' tumor metastatic to the orbit. | In a 2 1/2-year-old boy, a proptotic right lower lid developed one year after a primary abdominal mass proved to be Wilms' tumor. An orbital abscess or fungal infection was considered because the child was receiving chemotherapy. However, echography demonstrated a firm orbital mass, delineated its dimensions, and showe... | 198,592 | [
-0.1097797,
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0.2055502,
0.1325775,
0.2541941,
0.1502325,
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0.09240156,
-0.6639777,
-0.1146901,
0.1883775,
-0.1551854,
0.6724962,
0.1293998,
-0.2142003,
... |
Microassay with the NADH-induced light reaction, technique improved by means of purified enzymes from Achromobacter fischeri. | Purification of a commercial preparation of Achromobacter fischeri was carried out by agarose-suspension electrophoresis and by molecular-sieve chromatography. Both the luciferase and an oxidoreductase, catalyzing reduction of FMN with NADH, were obtained in more than one form. Flavins, liable to interfere with the lig... | 198,648 | [
-0.05093353,
-0.1608366,
-0.1043781,
0.1258515,
-0.2256204,
-0.4376061,
-0.1136448,
0.2170782,
0.1490663,
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0.3617664,
-0.1933778,
-0.1118614,
0.1372622,
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0.08170186,
-0.5081945,
0.2385817,
0.1161609,
0.3073279,
0.5776953,
-0.110071,
0.009518641,
0.... |
Iontrophoretic application of autonomic mediators and cyclic nucleotides in the sinus node cells. | The effects of intracellular application of noradrenaline, acetylcholine, cAMP and cGMP were studied in the sinus-node of the rabbit. Noradrenaline and acetylcholine were without effect on electrical activity. In about one third of cases, cAMP increased, and cGMP decreased the slope of slow depolarization. These result... | 198,678 | [
-0.1637202,
-0.3248499,
-0.4094285,
-0.2353606,
0.1872224,
-0.3567732,
-0.1114102,
-0.01516881,
-0.09774701,
0.2194,
-0.1311265,
0.01573824,
0.183943,
0.144568,
-0.5247124,
-0.3309603,
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-0.1143049,
0.01359293,
-0.06650499,
0.495139,
-0.1002448,
0.01492606,
0.... |
Neuromuscular blockade with anti-axoplasmic antibodies. | In the process of developing an immunopharmacologic method for identifying a "trophic" protein released from motor nerve terminals, a soluble fraction of peripheral nerve axoplasm was prepared. An attempt was made to eliminate contaminating myelin and basic protein. Antibodies were produced to soluble nerve proteins in... | 198,701 | [
-0.02503374,
-0.2872598,
-0.1704866,
-0.3083779,
-0.1990729,
-0.2289106,
-0.04981796,
-0.01620503,
-0.08648106,
-0.164184,
-0.1926966,
0.06187968,
0.1814592,
-0.04955996,
0.06139256,
0.0008873122,
-0.7588618,
0.1402246,
-0.1585744,
-0.100889,
0.03340254,
0.2257713,
0.2272... |
Conjugated estrogens and the overnight dexamethasone suppression test. | Basal (8:00 AM) serum cortisol levels in peri- or postmenopausal women treated with 0.625 mg daily of conjugated equine estrogens were only slightly higher than pretreatment levels. A 1.25 mg/day dosage resulted in a significant increase in basal serum cortisol levels. In women treated with either dosage, 8:00 AM serum... | 198,707 | [
-0.2614085,
0.4088491,
-0.1434304,
-0.2009541,
-0.1458364,
-0.07641736,
-0.05664088,
0.002163557,
-0.08315493,
-0.1283645,
0.1526498,
0.1177735,
0.3636804,
0.1045944,
-0.411966,
-0.381891,
-0.3708727,
0.201736,
-0.0483028,
0.03025114,
0.1085525,
0.1859103,
0.1186024,
-0... |
The activity of galactose-1-phosphate uridyltransferase and galactokinase in human fetal organs. | The activity of galactose-1-phosphate uridyltransferase (transferase) and galactokinase in several organs from human fetuses 7-28 weeks old was measured by using radioactive substrates and column chromatography for product identification. The specific activity of transferase and galactokinase increased with gestational... | 198,730 | [
0.03928285,
-0.2680534,
-0.3302914,
0.05795266,
0.579944,
-0.1492772,
-0.2288015,
0.09615108,
-0.1853408,
-0.08900606,
0.3410579,
-0.02540849,
0.2190989,
0.1260649,
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0.03434436,
-0.4569836,
0.1911319,
0.01267148,
0.06307036,
0.1395395,
0.4834908,
-0.1923524,
... |
The repeating nucleotide sequence in the repetitive mitochondrial DNA from a "low-density" petite mutant of yeast. | The repeating nucleotide sequence of 68 base pairs in the mtDNA from an ethidium-induced cytoplasmic petite mutant of yeast has been determined. For sequence analysis specifically primed and terminated RNA copies, obtained by in vitro transcription of the separated strands, were use. The sequence consists of 66 consecu... | 198,740 | [
-0.1428826,
0.07083429,
-0.2312783,
0.02050357,
0.3491846,
0.1228767,
0.1050405,
-0.2706463,
0.1624101,
0.1007793,
0.08825883,
-0.02842737,
0.03810953,
0.3168153,
-0.754815,
0.2073074,
-0.2804996,
0.1010096,
-0.2075934,
-0.1195687,
0.5155569,
0.2457734,
0.1601161,
-0.26... |
Restoration by T4 ligase of DNA sequences sensitive to "flush" cleaving restriction enzyme. | Fouteen "flush"-ended segments originate from the action of the restriction endonuclease Hae III of Haemophilus aegiptius on the DNA of the colicinogenic factor ColE 1 (A. Oka and M. Takanami, Nature, 264, 191, 1976). They are joined by the T4 polynucleotide ligase. The reaction can be monitored by gel electrophoresis,... | 198,743 | [
-0.01313986,
-0.135293,
-0.1911313,
-0.2220281,
-0.05342073,
-0.3721916,
-0.4265921,
-0.03833394,
0.3233193,
-0.3039215,
0.1611952,
-0.04886619,
0.1128438,
-0.01677955,
-0.5479705,
0.1366589,
-0.4993125,
-0.2788205,
-0.02503052,
0.1960195,
0.3203484,
-0.1344334,
-0.488309... |
Nucleotide sequence of the gene for the major structural protein of SV40 virus. | We have determined the sequence of the portion of Simian Virus 40 (SV40) that codes for the major structural protein of the virus. The gene contains 361 codons. Synonym codons for an amino acid are not used randomly. The dinucleotide CG occurs only once and there is 2 to 1 preference for uridylic acid in the third posi... | 198,745 | [
-0.04082823,
-0.0368931,
-0.2212017,
0.04873991,
0.4099008,
-0.03091387,
-0.1293266,
0.03625946,
0.2770482,
0.2274247,
0.2175644,
0.04037946,
0.09245273,
0.06048949,
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-0.05550977,
-0.09005086,
-0.04376423,
0.1048356,
-0.03057487,
0.2858355,
0.2258412,
-0.136480... |
Mechanisms by which diazepam, muscimol, and other drugs change the content of cGMP in cerebellar cortex. | THE CEREBELLUM CONSISTS OF TWO PARTS: the cerebellar nuclei whose connections to the various parts of the central nervous system coordinate muscle movements, and the cerebellar cortex which exerts an inhibitory influence on the cerebellar nuclei through the release of gamma-aminobutyric acid (gammaAbu) from Purkinje ce... | 198,792 | [
-0.1197963,
0.06967132,
-0.1199232,
-0.2868173,
0.3700956,
-0.420501,
-0.09380823,
0.01796165,
-0.1593385,
-0.07415951,
-0.06872319,
0.08244491,
0.09031483,
0.3313349,
-0.398456,
0.199929,
-0.4768469,
0.1718823,
0.1574847,
0.1541768,
0.2488249,
-0.1757016,
0.1208181,
-0... |
31P nuclear magnetic resonance kinetic measurements on adenylatekinase. | By using 31P double-resonance nucelar magnetic resonance, preliminary kinetic measurements were made on the equilibrium reaction 2ADP in equilibrium ATP +AMP catalyzed by adenylate kinase. The double-resonance method used consisted of selectively inverting the spin population in a particular chemical environment and ob... | 198,793 | [
-0.1782849,
-0.4317018,
-0.03829202,
-0.02100842,
0.1015128,
-0.1690465,
0.08043186,
0.3367942,
0.3332748,
0.04052956,
0.07380886,
0.1220179,
0.1121105,
0.2354671,
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-0.1938225,
-0.6596092,
0.03261751,
-0.3738928,
0.1146247,
0.557764,
0.0865894,
-0.206764,
0.0... |
Nucleotide sequences of ribosome recgonition sites in messenger RNAs of vesicular stomatitis virus. | The ribosome recognition sites from vesicular stomatitis virus mRNAs have been isolated by ribosome protection of the mixture of viral mRNAs followed by complete separation of the protected sites by two-dimensional gel electrophoresis. The sites from the four major mRNAs each contain a single AUG initiation codon, indi... | 198,795 | [
-0.1766004,
0.1559676,
-0.3649356,
-0.2903652,
0.1395841,
0.09774923,
-0.1433226,
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0.198445,
0.09633914,
0.0960202,
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-0.1005133,
0.06954814,
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-0.1421836,
-0.06020445,
0.2705981,
0.02921453,
0.483429,
0.08809457,
-0.09576056,
... |
Purification of simian virus 40 tumor antigen from a line of simian virus 40-transformed human cells. | Simian virus 40 tumor antigen can be isolated in a highly purified state from the nuclei ofSV80 cells, a continuous line of simian virus 40-transformed human fibroblasts. A five-step purification method was used. Its apparent molecular weight (in sodium dodecyl sulfate/polyacrylamide gels) is approximately 90,000-94,00... | 198,802 | [
-0.2418246,
0.01068333,
-0.1878233,
-0.09974104,
0.2258996,
-0.1194478,
-0.1887691,
0.07378968,
0.3086469,
0.2790079,
-0.06924379,
-0.1578718,
0.09393446,
-0.1105985,
-0.376392,
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-0.2603546,
0.09406851,
-0.02438283,
0.2308181,
0.101514,
0.1503092,
-0.1985559,
... |
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