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Health technology assessment Also in the UK, the Multidisciplinary Assessment of Technology Centre for Healthcare carries out HTA in collaboration with the health service, the NHS and various industrial partners. MATCH is organised into four themes addressing key HTA topics including Health Economics, Tools for Industr... | https://en.wikipedia.org/wiki?curid=22406877 |
Maturity (sedimentology) In sedimentary geology, maturity describes the composition and texture of grains in clastic rocks, most typically sandstones, resulting from different amounts of sediment transportation. A sediment is mature when the grains in a sediment become well-sorted and well-rounded due to weathering or ... | https://en.wikipedia.org/wiki?curid=22408256 |
LRGB LRGB, short for Luminance, Red, Green and Blue, is a photographic technique used in amateur astronomy for producing good quality color photographs by combining a high-quality black-and-white image with a lower-quality color image. In amateur astronomy, it is easier and cheaper to obtain good quality, high signal-t... | https://en.wikipedia.org/wiki?curid=22419272 |
Peloid (geology) Peloids are allochems that are composed of micrite, irrespective of size, shape, or origin. The two primary types of peloids are pellets and intraclasts. Another type of peloid is pseudo-oolith. | https://en.wikipedia.org/wiki?curid=22424179 |
Puelche (wind) A Puelche wind (in Spanish, "viento puelche") is a dry foehn-like eastern wind that occurs in south-central Chile. The wind owns its name from the Puelche people who inhabited the eastern slopes of the Andes. Puelche winds are mainly caused by South Pacific high pressure extending eastwards across the An... | https://en.wikipedia.org/wiki?curid=22441650 |
De Natura Fossilium is a scientific text written by Georg Bauer also known as Georgius Agricola, first published in 1546. The book represents the first scientific attempt to categorize minerals, rocks and sediments since the publication of Pliny's "Natural History". This text along with Agricola's other works including... | https://en.wikipedia.org/wiki?curid=22454273 |
Inuvik (crater) Inuvik is an Impact crater located outside the perennial north polar cap on Mars. The crater's diameter is 20.5 kilometres, and it lies at latitude 78.7°N, longitude 28.6°W. In 1988, the IAU's Working Group for Planetary System Nomenclature (WGPSN) named the crater after the town of Inuvik, Northwest Te... | https://en.wikipedia.org/wiki?curid=22465870 |
Davies equation The is an empirical extension of Debye–Hückel theory which can be used to calculate activity coefficients of electrolyte solutions at relatively high concentrations at 25 °C. The equation, originally published in 1938, was refined by fitting to experimental data. The final form of the equation gives the... | https://en.wikipedia.org/wiki?curid=22476314 |
Coupled-wave method In physics, the coupled-wave method (CWM) is a method for analysing the interaction between two electromagnetic waves in a crystal or a grating. | https://en.wikipedia.org/wiki?curid=22491755 |
Alessandro Vaciago (September 11, 1931 – November 17, 1993) was a Professor of Chemical Structure, University of Rome from 1971 to 1993. He also served as a Cultural Counselor for the Italian Embassy. The Accademia dei Lincei awards yearly the Vaciago Prize to distinguished researchers in different fields of science. | https://en.wikipedia.org/wiki?curid=22494743 |
Phrase name In Australian botany, a phrase name is an informal name given to a plant taxon that has not yet been given a formal scientific name. The term was adopted in 1992 by the Australian Herbarium Information Systems Committee. The species phrase name consists of four components — the generic name, "sp." (to indic... | https://en.wikipedia.org/wiki?curid=22529938 |
Ernst August Girschner Ernst August Girschner, usually just Ernst Girschner (29 October 1860 – 28 April 1914) was a German entomologist who specialised in Diptera. Girschner was born (and died) in Torgau, Province of Saxony. He taught at the Gymnasium in Torgau. Girschner described many new species of Diptera but made ... | https://en.wikipedia.org/wiki?curid=22533219 |
Michael L. W. Thewalt (born 5 December 1949 in Karlsruhe, Germany) is a Canadian physicist. He received his BSc from McMaster University in 1972. His MSc and PhD were from the University of British Columbia in the mid-1970s. He teaches at Simon Fraser University and is known for researching semiconductors, especially i... | https://en.wikipedia.org/wiki?curid=22534568 |
Marine Life Information Network The (MarLIN) is an information system for marine biodiversity for Great Britain and Ireland. MarLIN was established in 1998 by the Marine Biological Association together with the environmental protection agencies and academic institutions in Britain and Ireland. The MarLIN data access pr... | https://en.wikipedia.org/wiki?curid=22536663 |
Fusain is a fossilised carbon deposit which, after some controversy, has been identified as fossilised charcoal. It is fibrous, black and opaque, and often preserves details of cell wall architecture. Wood-derived fusain usually takes the form of cubic blocks, whereas fusain from other plant material may take the form ... | https://en.wikipedia.org/wiki?curid=22547944 |
Himiko (Lyman-alpha blob) Himiko is a large gas cloud found at redshift of z=6.6 that predates similar Lyman-alpha blobs. At time of discovery, researchers said it "may represent the most massive object ever discovered in the early universe." It is located in Cetus at redshift z=6.595, about 12.9 billion light years fr... | https://en.wikipedia.org/wiki?curid=22548217 |
Very long chain fatty acid A very long chain fatty acid (VLCFA) is a fatty acid with 22 or more carbons. Their biosynthesis occurs in the endoplasmic reticulum. VLCFA's can represent up to a few percent of the total fatty acid content of a cell. Unlike most fatty acids, VLCFAs are too long to be metabolized in the mito... | https://en.wikipedia.org/wiki?curid=22561373 |
Purnell equation The is an equation used in analytical chemistry to calculate the resolution "R" between two peaks in a chromatogram. where The higher the resolution, the better the separation. | https://en.wikipedia.org/wiki?curid=22562598 |
Do-it-yourself biology (DIY biology, DIY bio) is a growing biotechnological social movement in which individuals, communities, and small organizations study biology and life science using the same methods as traditional research institutions. DIY biology is primarily undertaken by individuals with extensive research tr... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology In 2005 Rob Carlson wrote in an article in "Wired": "The era of garage biology is upon us. Want to participate? Take a moment to buy yourself a lab on eBay." He then set up a garage lab the same year, working on a project he had previously worked at the Molecular Sciences Institute in Berkeley, C... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology Recent work combining open-source hardware of microcontrollers like the Arduino and RepRap 3-D printers, very low-cost scientific instruments have been developed. Many organizations maintain a laboratory akin to a wet-lab makerspace, providing equipment and supplies for members. Many organization... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology Most advocacy in biohacking is about the safety, accessibility and future legality of experimentation. Todd Kuiken of the Woodrow Wilson Center proposes that through safety and self-governance, DIY biologists won't be in need of regulation. Josiah Zayner has proposed that safety is inherent in bi... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology Other experiments that have involved medical treatments include a whole body microbiome transplant and the creation of open source artificial pancreases for diabetics. Grinders are a subculture of biohackers that focus on implanting technology or introducing chemicals into the body to enhance or ... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology The laboratory consequently kept possession of the transgenic rabbit which it had created and funded and the "transgenic art" was never exhibited at the Digital Avignon festival [2000] as intended. Kac—claiming that his rabbit was the first GFP bunny created in the name of Art—used this dispute t... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology Concerns about biohackers creating pathogens in unmonitored garage laboratories led the Federal Bureau of Investigation (FBI) to begin sending its representatives to DIYbio conferences in 2009. The arrest and prosecution of some members for their work with harmless microbes, such as artivist Stev... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology Pat Mooney, executive director of ETC Group, is a critic of biohacking who argues that—using a laptop computer, published gene sequence information, and mail-order synthetic DNA—just about anyone has the potential to construct genes or entire genomes from scratch (including those of the lethal pa... | https://en.wikipedia.org/wiki?curid=22562859 |
Do-it-yourself biology Enthusiasts argue that fear of potential hazards should be met with increased research and education rather than closing the door on the profound positive impacts that distributed biological technology will have on human health, the environment, and the standard of living around the world. Due to... | https://en.wikipedia.org/wiki?curid=22562859 |
Belarusian Nature and Environment Museum The Museum of Nature and Environment of the Republic of Belarus is a museum in Minsk, Belarus, founded in 1991 at Minsk on the basis of the nature of Belarusian National History and Culture Museum. There are more than 40 thousand exhibits inside an exposition area of 350 m². In ... | https://en.wikipedia.org/wiki?curid=22576474 |
Stoletov curve shows the dependence of the magnetic permeability formula_1 of ferromagnetics on the intensity of the applied magnetic field "H". The curve is named after physicist Aleksandr Stoletov who analyzed in a long series of experiments the magnetic properties of iron rings in the period 1871–1872 during his sta... | https://en.wikipedia.org/wiki?curid=22576960 |
Flatness (liquids) Flatness refers to the shape of a liquid's free surface. On planet Earth, the flatness of a liquid is a function of the curvature of the Earth, and from trigonometry, can be found to deviate from true flatness by approximately 19.6 nanometers over an area of 1 square meter, a deviation which is domin... | https://en.wikipedia.org/wiki?curid=22579173 |
Flora of Borneo The flora of Borneo include 15 species of dicot tree, 37 species of non-tree dicot and 49 species of monocot endemic to the rich forest of Brunei Darussalam. Borneo is also home to the world's largest flower, the Rafflesia Arnoldii, this is the largest flower in the world and can reach up to 15 pounds i... | https://en.wikipedia.org/wiki?curid=22585258 |
Vortex stretching In fluid dynamics, vortex stretching is the lengthening of vortices in three-dimensional fluid flow, associated with a corresponding increase of the component of vorticity in the stretching direction—due to the conservation of angular momentum. is associated with a particular term in the vorticity equ... | https://en.wikipedia.org/wiki?curid=22586949 |
Eobacteria is a proposed clade characterized by Cavalier-Smith. Species in this group lack lipopolysaccharide. The clade includes Hadobacteria and Chlorobacteria. | https://en.wikipedia.org/wiki?curid=22603691 |
BioCryst Pharmaceuticals BioCryst Pharmaceuticals, Inc. is an American pharmaceutical company headquartered in Durham, North Carolina. The company focuses on orphan & autoimmune diseases, and antivirals. The company's most advanced drug candidate is the antiviral Peramivir, which is approved in Japan, Korea and China. ... | https://en.wikipedia.org/wiki?curid=22617127 |
Ruze's equation is an equation relating the gain of an antenna to the RMS of the random surface errors. The equation is applicable to parabolic reflector and antennas, and recently extended to phased arrays. The equation is named after John Ruze who introduced the equation in a paper he wrote in 1952. The equation stat... | https://en.wikipedia.org/wiki?curid=22630452 |
Pickering (Martian crater) Pickering Crater is a crater in the Phaethontis quadrangle on Mars, located at 33.1° south latitude and 132.5° west longitude. It is in diameter. Lava flow fronts are visible within the crater, and the source of the lava is Arsia Mons. The lava has flowed around the central peak of the crater... | https://en.wikipedia.org/wiki?curid=22640525 |
Kipini (crater) Kipini is an impact crater in the Oxia Palus quadrangle of Mars. It is located at 26.1° N and 31.6° W It is named after Kipini, a town in Kenya. Impact craters generally have a rim with ejecta around them, in contrast volcanic craters usually do not have a rim or ejecta deposits. As craters get larger (... | https://en.wikipedia.org/wiki?curid=22641961 |
Sagan (crater) Sagan is an impact crater on Mars, located in the Oxia Palus quadrangle at 10.8° N and 30.7° W. It measures approximately 90 kilometers in diameter and was named after American astronomer Carl Sagan, who founded the Planetary Society and is best known for the television series "". The naming was approved... | https://en.wikipedia.org/wiki?curid=22642004 |
Fesenkov (Martian crater) Fesenkov Crater is an impact crater in the Lunae Palus quadrangle of Mars. It is located at 21.8° N and 86.7° W. It was named after Vasilii G. Fesenkov, a Russian astrophysicist (1889–1972). | https://en.wikipedia.org/wiki?curid=22642411 |
Pangboche (crater) Pangboche is a young impact crater on Mars, located in the Tharsis quadrangle near the summit of Olympus Mons. It was named after a village in Nepal. It measures 10 kilometer in diameter, and is located at 17.47° N and 133.4° W. The average depth of the crater is 954 m, and the height of the crater r... | https://en.wikipedia.org/wiki?curid=22646014 |
Electrocapillarity or electrocapillary phenomena are the phenomena related to changes in the surface energy (or interfacial tension) of the dropping mercury electrode (DME), or in principle, any electrode, as the electrode potential changes or the electrolytic solution composition and concentration change. The term "el... | https://en.wikipedia.org/wiki?curid=22649696 |
Stoletov's law (or the first law of photoeffect) for photoelectric effect establishes the direct proportionality between the intensity of electromagnetic radiation acting on a metallic surface and the photocurrent induced by this radiation. The law was discovered by Aleksandr Stoletov in 1888. | https://en.wikipedia.org/wiki?curid=22661771 |
Isopach map An isopach map () illustrates thickness variations within a tabular unit, layer or stratum. Isopachs are contour lines of equal thickness over an area. Isopach maps are utilized in hydrographic survey, stratigraphy, sedimentology, structural geology, petroleum geology and volcanology. An isopach map is simi... | https://en.wikipedia.org/wiki?curid=22665032 |
Jack Hawkes (botanist) John Gregory "Jack" Hawkes OBE FLS (27 June 1915 in Bristol – 6 September 2007 in Reading) was a British botanist, Mason Professor of Botany at the University of Birmingham. He specialised in studying the taxonomy of wild potato species ("Solanum" sect. "Petota"), identified sources of resistance... | https://en.wikipedia.org/wiki?curid=22666808 |
Sigma Gamma Epsilon The Society of (ΣΓΕ) is a national honor society to recognize scholarship in the earth sciences founded in 1915 at the University of Kansas. It has chartered more than 200 chapters at colleges and universities across the United States. The Society was established to recognize scholarship and profess... | https://en.wikipedia.org/wiki?curid=22679533 |
Matrix string theory In physics, matrix string theory is a set of equations that describe superstring theory in a non-perturbative framework. Type IIA string theory can be shown to be equivalent to a maximally supersymmetric two-dimensional gauge theory, the gauge group of which is U("N") for a large value of "N". This... | https://en.wikipedia.org/wiki?curid=22684803 |
Matvei Petrovich Bronstein (, , Vinnytsia – February 18, 1938) was a Soviet theoretical physicist, a pioneer of quantum gravity, author of works in astrophysics, semiconductors, quantum electrodynamics and cosmology, as well as of a number of books in popular science for children. He introduced the cGh scheme for class... | https://en.wikipedia.org/wiki?curid=22684836 |
Warm–hot intergalactic medium The warm–hot intergalactic medium (WHIM) refers to a sparse, warm-to-hot (10 to 10 K) plasma that cosmologists believe to exist in the spaces between galaxies and to contain 40–50% of the baryonic 'normal matter' in the universe at the current epoch. The WHIM can be described as a web of h... | https://en.wikipedia.org/wiki?curid=22689597 |
Warm–hot intergalactic medium In May 2010 a giant reservoir of WHIM was detected by the Chandra X-ray Observatory lying along the wall-shaped structure of galaxies (Sculptor Wall) some 400 million light-years from Earth. In 2018, observations of highly-ionized extragalactic oxygen atoms appeared to confirm simulations ... | https://en.wikipedia.org/wiki?curid=22689597 |
Nuclear interaction length is the mean distance travelled by a hadronic particle before undergoing an inelastic nuclear interaction. | https://en.wikipedia.org/wiki?curid=22692296 |
Nuclear collision length is the mean free path of a particle before undergoing a nuclear reaction, for a given particle in a given medium. The collision length is smaller than the nuclear interaction length because the latter excludes the elastic and quasi-elastic (diffractive) reactions from its definition. | https://en.wikipedia.org/wiki?curid=22693121 |
Shock waves in astrophysics Shock waves are common in astrophysical environments. Because of the low ambient density, most astronomical shocks are collisionless. This means that the shocks are not formed by two-body Coulomb collisions, since the mean free path for these collisions is too large, often exceeding the size... | https://en.wikipedia.org/wiki?curid=22703376 |
Shock waves in astrophysics These shocks are unique to astrophysical environments, and can be either collisionless or radiation mediated. Relativistic shocks are theoretically expected in gamma ray bursts, active galactic nucleus jets and in some types of supernovae. | https://en.wikipedia.org/wiki?curid=22703376 |
Magnet-assisted transfection is a transfection method which uses magnetic interactions to deliver DNA into target cells. Nucleic acids are associated with magnetic nanoparticles, and magnetic fields drive the nucleic acid-particle complexes into target cells, where the nucleic acids are released. Nanoparticles used as ... | https://en.wikipedia.org/wiki?curid=22714697 |
Magnet-assisted transfection In most cases the increased iron concentration in culture media does not lead to cytotoxic effects. is a relatively new and time-saving method to introduce nucleic acids into a target cell with increased efficiency. In particular, adherent mammalian cell lines and primary cell cultures show... | https://en.wikipedia.org/wiki?curid=22714697 |
Richard Hanitsch Karl (22 December 1860 – 11 August 1940) was a German-born entomologist and museum curator who served as the director of the Raffles Museum in Singapore in the early 20th century. Hanitsch was born at Grossenstein in Thuringia, Germany. He studied at the University of Jena, where he obtained his PhD. F... | https://en.wikipedia.org/wiki?curid=22725654 |
Winslow (crater) Winslow is an impact crater on Mars, located in the Iapygia quadrangle at -3.74°S latitude and 59.16°E longitude. It measures in diameter and was named after Winslow, Arizona, a town just east of Meteor Crater, which has a similar size and resembles Winslow crater. The two craters also have similar inf... | https://en.wikipedia.org/wiki?curid=22728887 |
Onon (crater) Onon is an impact crater on Mars, located in the Amenthes quadrangle at 16.3° N and 257.6° W. It measures 3.5 kilometer in diameter and was named after Onon, a town in Mongolia. Impact craters generally have a rim with ejecta around them, in contrast volcanic craters usually do not have a rim or ejecta de... | https://en.wikipedia.org/wiki?curid=22728937 |
Thila (crater) Thila is an impact crater on Mars, located in the Elysium quadrangle at 18.09° N and 204.58° W. It measures approximately 5.3 kilometers in diameter and was named after the village of Thila in Yemen. | https://en.wikipedia.org/wiki?curid=22729050 |
Sirtris Pharmaceuticals Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Conceived in 2004 by Harvard University biologist David Sinclair and serial entrepreneur Andrew Perlman, and founded that year by Sinclair an... | https://en.wikipedia.org/wiki?curid=22733563 |
Sirtris Pharmaceuticals Studies published in 2009 and early 2010 by scientists from Amgen and Pfizer cast doubt on whether SIRT1 was directly activated by resveratrol and showed that the apparent activity was actually due to a fluorescent reagent used in the experiments. In August 2010, a nonprofit called the Healthy L... | https://en.wikipedia.org/wiki?curid=22733563 |
Puńsk (crater) Puńsk is an impact crater on Mars, located in the Oxia Palus quadrangle at 20.8° N and 41.2° W. It measures 11.6 kilometers in diameter and was named after the village of Puńsk in Poland. Impact craters generally have a rim with ejecta around them, in contrast volcanic craters usually do not have a rim o... | https://en.wikipedia.org/wiki?curid=22734686 |
List of systems biology conferences Systems biology is a biological study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective (integration instead of reduction) to study them. Particularly from year 2000 onwards, the term is used widely in the bioscienc... | https://en.wikipedia.org/wiki?curid=22770838 |
Latex beads are the polymeric particles suspended in a latex. They are used in applications as contrast agents for fluorescent imaging, as particles for flow tracking, or as biological carriers. | https://en.wikipedia.org/wiki?curid=22774082 |
Halothermal circulation See Thermohaline Circulation. The term halothermal circulation refers to the part of the large-scale ocean circulation that is driven by global density gradients created by surface heat and evaporation. The adjective halothermal derives from "halo-" referring to salt content and "-thermal" refer... | https://en.wikipedia.org/wiki?curid=22784944 |
Mole map (chemistry) In chemistry, the mole map is a graphical representation of an algorithm that compares molar mass, number of particles / mole, and factors from balanced equations or other formulae. | https://en.wikipedia.org/wiki?curid=22792377 |
Strep-tag The Strep-tag® system is a method which allows the purification and detection of proteins by affinity chromatography. The II is a synthetic peptide consisting of eight amino acids (Trp-Ser-His-Pro-Gln-Phe-Glu-Lys). This peptide sequence exhibits intrinsic affinity towards Strep-Tactin®, a specifically enginee... | https://en.wikipedia.org/wiki?curid=22810498 |
Strep-tag Just like other short-affinity tags (His-tag, FLAG-tag), the can be easily fused to recombinant proteins during subcloning of its cDNA or gene. For its expression various vectors for various host organisms ("E. coli", yeast, insect, and mammalian cells) are available. A particular benefit of the is its rather... | https://en.wikipedia.org/wiki?curid=22810498 |
Strep-tag The removal of desthiobiotin is indicated by a color change from yellow-orange to red (step 4+5). Finally, the HABA solution is washed out with a small volume of running buffer, thus making the column ready to use for the next purification run. The system offers a highly selective tool to purify proteins unde... | https://en.wikipedia.org/wiki?curid=22810498 |
DNA-encoded chemical library DNA-encoded chemical libraries (DEL) is a technology for the synthesis and screening on unprecedented scale of collections of small molecule compounds. DEL is used in medicinal chemistry to bridge the fields of combinatorial chemistry and molecular biology. The aim of DEL technology is to a... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library So, in addition to the general discovery of target specific molecular compounds, the availability of binders to pharmacologically important, but so-far “undruggable” target proteins opens new possibilities to develop novel drugs for diseases that could not be treated so far. In eliminating ... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library Phage-displayed antibodies can be isolated from large antibody libraries by mimicking molecular evolution: through rounds of selection (on an immobilized protein target), amplification and translation. In DEL the linkage of a small molecule to an identifier DNA code allows the facile identi... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library Brenner and Janda suggested to generate individual encoded library members by an alternating parallel combinatorial synthesis of the heteropolymeric chemical compound and the appropriate oligonucleotide sequence on the same bead in a “split-&-pool”-based fashion (see below). Since unprotect... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library Hits can be identified by DNA sequencing, however DNA translation and therefore molecular evolution is not feasible by these methods. The split and pool approaches developed by researchers at Praecis Pharmaceuticals (now owned by GlaxoSmithKline), Nuevolution (Copenhagen, Denmark) and ESAC ... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library Furthermore, the DNA tagged BBs enable the generation of a genetic code for synthesized compounds and artificial translation of the genetic code is possible: That is the BB's can be recalled by the PCR-amplified genetic code, and the library compounds can be regenerated. This, in turn, enab... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library A promising strategy for the construction of DNA-encoded libraries is represented by the use of multifunctional building blocks covalently conjugated to an oligonucleotide serving as a “core structure” for library synthesis. In a ‘pool-and-split’ fashion a set of multifunctional scaffolds u... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library However the stepwise addition of at least three independent sets of chemical moieties to a tri-functional core building block for the construction and encoding of a very large DNA-encoded library (comprising up to 10 compounds) can also be envisaged.(Fig.2) Encoded Self-Assembling Chemical ... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library The compound represents the core structure of a series of portable albumin binding molecules and of Albufluor a recently developed fluorescein angiographic contrast agent currently under clinical evaluation. ESAC technology has been used for the isolation of potent inhibitors of bovine tryp... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library In 2001 David Liu and co-workers showed that complementary DNA oligonucleotides can be used to assist certain synthetic reactions, which do not efficiently take place in solution at low concentration. A DNA-heteroduplex was used to accelerate the reaction between chemical moieties displayed... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library The center of the DNA junction constitutes a volume on the order of a yoctoliter, hence the name YoctoReactor. This volume contains a single molecule reaction yielding reaction concentrations in the high mM range. The effective concentration facilitated by the DNA greatly accelerates chemic... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library The yR design approach provides an unvarying reaction site with regard to both (a) distance between reactants and (b) sequence environment surrounding the reaction site. Furthermore, the intimate connection between the code and the BB on the oligo-BB moieties which are mixed combinatorially... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library The low noise and background signal characteristic of BTE is attributed to the "dilution" of the random signal, the lack of surface artifacts and the high fidelity of the yR library and screening method. Screening is performed in a single tube method. Biologically active hits are identified... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library After selection and PCR amplification of the DNA-tags of the library compounds, concatamers containing multiple coding sequences were generated and ligated into a vector. Following Sanger sequencing of a representative number of the resulting colonies revealed the frequencies of the codes p... | https://en.wikipedia.org/wiki?curid=22810768 |
DNA-encoded chemical library Afterwards, microarrays are analyzed using a laser scan and spot intensities detected and quantified. The enrichment of the preferential binding compounds is revealed comparing the spots intensity of the DNA-microarray slide before and after selection. According to the complexity of the DNA... | https://en.wikipedia.org/wiki?curid=22810768 |
Keller's reagent can refer to either of two different mixtures of acids. In metallurgy, is a mixture of nitric acid, hydrochloric acid, and hydrofluoric acid, used to etch aluminum alloys to reveal their grain boundaries and orientations. It is also sometimes called Dix–Keller reagent, after E. H. Dix, Jr., and Fred Ke... | https://en.wikipedia.org/wiki?curid=22812166 |
Golden Eye Diamond The is a flawless Fancy Intense Yellow diamond, claimed by one of its past owners to be the world's largest of its cut and color. It is believed to come from the Kimberley area of South Africa. Tom Moses, a senior vice president with the Gemological Institute of America, agrees that it came from Sout... | https://en.wikipedia.org/wiki?curid=22813846 |
Golden Eye Diamond The uncontested evidence showed that the had been obtained from the VanWyke family of Kimberly South Africa most recently, and that the stone had been held by the family for some 150-years. The original VanWyke was neighbor to the De Beers, and discovered the 124.5 carat paragon on his property in th... | https://en.wikipedia.org/wiki?curid=22813846 |
Lithium depletion boundary The lithium depletion boundary (LDB) technique is a method proposed for dating open clusters based on a determination of the lithium abundances of a cluster's stars whose masses are at about the hydrogen burning mass limit. | https://en.wikipedia.org/wiki?curid=22814744 |
Radioactive Substances Act 1993 The (RSA93) deals with the control of radioactive material and disposal of radioactive waste in the United Kingdom. On 6 April 2010 the Environmental Permitting (England and Wales) Regulations 2010 came into force. These new regulations repeal, amend and replace much of in England and Wa... | https://en.wikipedia.org/wiki?curid=22832114 |
Josef Kozeny Josef Alexander Kozeny (February 25, 1889 – April 19, 1967) was an Austrian hydraulic engineer and physicist. Today he is mainly remembered for the Kozeny–Carman equation which describes fluid flowing through a packed bed of solids. Born in Josefstadt, Bohemia, Kozeny moved to Prague to study at the German... | https://en.wikipedia.org/wiki?curid=22853837 |
Josef Kozeny Used to calculate the flow of a liquid through a packed bed of solids, the equation was first proposed by Kozeny in 1927 and later modified by Philip Carman. | https://en.wikipedia.org/wiki?curid=22853837 |
PGC 214560 is a galaxy in the Hercules constellation. It is currently interacting with the galaxy SDSS J170007.01+230739.1. has a similar appearance to the Mice Galaxies and is home to supernovae 2008eq, CBET 1460. | https://en.wikipedia.org/wiki?curid=22855004 |
Biermann battery In astrophysics, the is a process by which a weak seed magnetic field can be generated from zero initial conditions. The relative motion between electrons and ions is driven by rotation. The process was discovered by Ludwig Biermann in 1950. | https://en.wikipedia.org/wiki?curid=22859001 |
Jainendra K. Jain Jainendra K. Jain, an Indian-American physicist, is the Evan Pugh University Professor and Erwin W. Mueller Professor of Physics at Pennsylvania State University. He is also Infosys Chair Visiting Professor at IISc, Bangalore. Jain is known for his theoretical work on quantum many body systems, most n... | https://en.wikipedia.org/wiki?curid=22863393 |
Jainendra K. Jain As the originator of the exotic particles called composite fermions, he developed the composite fermion theory of the fractional quantum Hall effect and unified the fractional and the integral quantum Hall effects. His writings include a monograph "Composite Fermions", published in 2007 by the Cambrid... | https://en.wikipedia.org/wiki?curid=22863393 |
Biohappiness is the elevation of utility in humans through biological methods, including germline engineering through screening embryos with genes associated with a high level of happiness, or the use of drugs intended to raise baseline levels of happiness. The object is to facilitate the achievement of a state of "bet... | https://en.wikipedia.org/wiki?curid=22866377 |
Galdakao (crater) Galdakao Crater is a topographic depression in the Aeolis quadrangle of Mars, located at 13.5° South and 183.5° West. It is 35 km in diameter and was named after Galdakao, a town in Basque Country, northern Spain. | https://en.wikipedia.org/wiki?curid=22874780 |
Masursky (Martian crater) Masursky is a crater on Mars, located in the Oxia Palus quadrangle at 12.1° North and 32.4° West. It measures 117.9 kilometers in diameter and was named after Harold Masursky, an American astrogeologist (1922–1990). The large blocks near the center of the crater are known as Chryse Chaos. The ... | https://en.wikipedia.org/wiki?curid=22874954 |
Baltisk is a crater in the Argyre quadrangle of Mars. It is located at 42.7° South and 54.7° West, is 52 km in diameter, and was named after a town in Russia. is located on the western edge of the Argyre impact basin. Impact craters generally have a rim with ejecta around them, in contrast volcanic craters usually do n... | https://en.wikipedia.org/wiki?curid=22875184 |
Anders Flodström (born 1944) is a Swedish professor of materials physics at the Royal Institute of Technology. He was previously the rector of Linköping University from 1996 to 1999 and of the Royal Institute of Technology from 1999 to 2007 and University Chancellor of Sweden and head of the Swedish National Agency for... | https://en.wikipedia.org/wiki?curid=22875437 |
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