text stringlengths 11 1.65k | source stringlengths 38 44 |
|---|---|
Plastic magnet The plastic magnet was made from a polymer made of tetracyanoethylene (TCNE) combined with manganese (Mn) ions – atoms of the metal manganese with electrons removed. The magnet functioned up to a temperature of . | https://en.wikipedia.org/wiki?curid=950025 |
Classical XY model The classical XY model (sometimes also called classical rotor (rotator) model or O(2) model) is a lattice model of statistical mechanics. It is the special case of the "n"-vector model for . Given a -dimensional lattice , per each lattice site there is a two-dimensional, unit-length vector The spin c... | https://en.wikipedia.org/wiki?curid=954006 |
Classical XY model Independently of the range of the interaction, at low enough temperature the magnetization is positive. In general, the XY model can be seen as a specialization of Stanley's "n"-vector model | https://en.wikipedia.org/wiki?curid=954006 |
The Great Devonian Controversy began in 1834 when Roderick Murchison disagreed with Henry De la Beche as to the dating of certain petrified plants found in coals in the Greywacke strata in North Devon, England. De La Beche was claiming that since Carboniferous fossils were found deep in the Greywacke strata, which itse... | https://en.wikipedia.org/wiki?curid=960678 |
ACES (computational chemistry) Aces II (Advanced Concepts in Electronic Structure Theory) is an ab initio computational chemistry package for performing high-level quantum chemical ab initio calculations. Its major strength is the accurate calculation of atomic and molecular energies as well as properties using many-bo... | https://en.wikipedia.org/wiki?curid=961605 |
ACES (computational chemistry) The first was maintained by the Bartlett group at the University of Florida, and the other (known as ACESII-MAB) was maintained by groups at the University of Texas, Universitaet Mainz in Germany, and ELTE in Budapest, Hungary. The latter has recently been renamed as CFOUR. Aces III is a ... | https://en.wikipedia.org/wiki?curid=961605 |
NGC 3628 NGC 3628, also known as the Hamburger Galaxy or Sarah's Galaxy, is an unbarred spiral galaxy about 35 million light-years away in the constellation Leo. It was discovered by William Herschel in 1784. It has an approximately 300,000 light-years long tidal tail. Along with M65 and M66, forms the Leo Triplet, a s... | https://en.wikipedia.org/wiki?curid=964170 |
Henry Charles Gordon (December 23, 1925 – September 24, 1996), (Col, USAF), was an American aeronautical engineer, U.S. Air Force officer, test pilot, and astronaut in the X-20 Dyna-Soar program. Gordon was born in Valparaiso, Indiana, on December 23, 1925. In 1950 he earned his Bachelor of Science degree in Aeronautic... | https://en.wikipedia.org/wiki?curid=970716 |
Small telescope A small telescope is generally considered by professional astronomers to be any reflecting telescope with a primary mirror that is less than in diameter. By amateur standards, a small telescope can have a primary mirror/aperture less than in diameter. Little if any professional-level research is perform... | https://en.wikipedia.org/wiki?curid=971612 |
Small telescope Some reflecting types are Newtonian, Schmidt–Cassegrain, Maksutov-Cassegrain, and Maksutov-Newtonian. Even sophisticated designs, such as the Ritchey–Chrétien and (corrected) Dall–Kirkham, which have traditionally been the preserve of large professional-grade instruments, have become available to amateu... | https://en.wikipedia.org/wiki?curid=971612 |
Russell L. Rogers Russell Lee Rogers (April 12, 1928 – September 13, 1967), (Lt Col, USAF), was an American electrical engineer, U.S. Air Force officer, test pilot, and astronaut in the X-20 Dyna-Soar program. He was born on April 12, 1928 in Lawrence, Kansas. He received a Bachelor of Science degree in Electrical Engi... | https://en.wikipedia.org/wiki?curid=972042 |
James W. Wood James Wayne Wood (August 9, 1924 – January 1, 1990), (Col, USAF), was an American aeronautical engineer, U.S. Air Force officer, test pilot, and astronaut in the X-20 Dyna-Soar program. He was born on August 9, 1924, in Paragould, Arkansas, to Henry P. Wood (1894–1983) and Alfreda Wood ("née" Lowrie; 1900... | https://en.wikipedia.org/wiki?curid=972753 |
James W. Wood He died in Melbourne, Florida, on January 1, 1990, of natural causes, aged 65. | https://en.wikipedia.org/wiki?curid=972753 |
Tong Dizhou (; May 28, 1902 － March 30, 1979) was a Chinese embryologist known for his contributions to the field of cloning. He was a vice president of Chinese Academy of Science. Born in Yinxian, Zhejiang province, Tong graduated from Fudan University in 1924 with a degree in psychology, and received a PhD in 1930 fr... | https://en.wikipedia.org/wiki?curid=973296 |
True longitude In celestial mechanics true longitude is the ecliptic longitude at which an orbiting body could actually be found if its inclination were zero. Together with the inclination and the ascending node, the true longitude can tell us the precise direction from the central object at which the body would be loc... | https://en.wikipedia.org/wiki?curid=976840 |
Leo Buss Leo W. Buss (born 1953) is a retired Professor at Yale University's departments of geology, geophysics, and ecology and evolutionary biology. He graduated from Johns Hopkins University with a B.A., M.A., and Ph.D in 1979. His evolutionary developmental biology book approaches the subject of the evolution of me... | https://en.wikipedia.org/wiki?curid=977351 |
Justus Ludwig Adolf Roth (September 15, 1818, Hamburg – April 1, 1892) was a German geologist and mineralogist. In 1844 he obtained his doctorate from the University of Jena and spent the next few years working as a pharmacist in Hamburg. In 1848 he relocated to Berlin, where he came under the influence of Gustav Rose ... | https://en.wikipedia.org/wiki?curid=977546 |
HCG 87 is a compact group of galaxies listed in the Hickson Compact Group Catalogue. This group is about 400 million light-years away in the constellation Capricornus. The group distinguishes itself as one of the most compact groups of galaxies, hosting two active galactic nuclei and a starburst among its three members... | https://en.wikipedia.org/wiki?curid=977799 |
Non-inclined orbit A non-inclined orbit is an orbit coplanar with a plane of reference. The orbital inclination is 0° for prograde orbits, and π (180°) for retrograde ones. If the plane of reference is a massive spheroid body's equatorial plane, these orbits are called equatorial; if the plane of reference is the eclip... | https://en.wikipedia.org/wiki?curid=978733 |
Gilead Sciences Gilead Sciences, Inc. , is an American biopharmaceutical company that researches, develops and commercializes drugs. The company focuses primarily on antiviral drugs used in the treatment of HIV, hepatitis B, hepatitis C, and influenza, including Harvoni and Sovaldi. Headquartered and founded in Foster ... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences Riordan tried to recruit Warren Buffett as an investor and board member, but was unsuccessful. The company focused its early research on making small strands of DNA (oligomers, or more particularly, oligonucleotides) to target specific genetic code sequences – that is, antisense therapy, a form of gene ... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences At the time, NeXstar's annual sales of $130 million was three times Gilead's sales; it sold AmBisome, an injectable fungal treatment, and DaunoXome, an oncology drug taken by HIV patients. That same year, Roche announced FDA approval of Tamiflu (oseltamivir) for the treatment of influenza. Tamiflu was o... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences During this era, Gilead completed its gradual evolution from a biotech startup into a pharmaceutical company. The "San Francisco Chronicle" noted that by 2003, the Gilead corporate campus in Foster City had expanded to "seven low-slung sand-colored buildings around a tiny lake on which ducks happily pad... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences for $365 million. The acquisition of Corus signaled Gilead's entry into the respiratory arena. Corus was developing aztreonam lysine for the treatment of patients with cystic fibrosis who are infected with "Pseudomonas aeruginosa". In July 2006, the U.S. Food and Drug Administration (FDA) approved Atrip... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences 4 billion, bringing Ranexa and Lexiscan into Gilead. Ranexa is a cardiovascular drug used to treat chest pain related to coronary artery disease, with both of these products and pipeline building out Gilead's cardiovascular franchise. Later that year, the company was named one of the Fastest Growing Com... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences 2 million square feet. On July 16, 2012, the FDA approved Gilead's Truvada for prevention of HIV infection (it was already approved for treating HIV). The pill was a preventive measure (PrEP) for people at high risk of getting HIV through sexual activity. In 2013, the company acquired YM Biosciences, In... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences In November, the company announced it will acquire Cell Design Labs for up to $567 million, after it indirectly acquired a stake of 12.2% via the Kite Pharma deal. On May 9, 2019, the U.S. Department of Health and Human Services announced that will donate Truvada, the only drug approved to prevent infec... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences "Forbes" magazine ranked Gilead its number 4 drug company, citing a market capitalization of US$113 billion and stock appreciation of 100%, and describing their 2011 purchase of Pharmasset for $11 billion as "one of the best pharma acquisitions ever". Deutsche Bank estimated Sovaldi sales in the year's ... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences By 2017, Gilead was reporting drastic drops in Sovaldi revenue from year to year, not only because of pricing pressure but because the number of suitable patients decreased. Later single-pill combinations were Epclusa (with velpatasvir) and Vosevi (with velpatasvir and voxilaprevir). For the fiscal year... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences profits, reporting that "A US pharmaceutical firm used a controversial tax loophole arrangement to shift almost €20 billion in profits through an Irish entity in just two years". Several class-action lawsuits have been filed against Gilead over allegations that the company deliberately delayed developme... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences Gilead has also tried to eliminate competition in lucrative markets by entering voluntary licensing agreements (VLA) with companies from developing countries such as India, which mandated the limitation of the latter's operations to less lucrative markets. The company has also been criticized for creati... | https://en.wikipedia.org/wiki?curid=978997 |
Gilead Sciences government funding. After facing strong reactions, Gilead gave up the "orphan drug" status for remdesivir on March 25th. Gilead retains 20-year remdesivir patents in more than 70 countries. Gilead has also been accused of price-gouging on other medications developed with public funding, including AIDS P... | https://en.wikipedia.org/wiki?curid=978997 |
Working range Each instrument used in analytical chemistry has a useful working range. This is the range of concentration (or mass) that can be adequately determined by the instrument, where the instrument provides a useful signal that can be related to the concentration of the analyte. All instruments have an upper an... | https://en.wikipedia.org/wiki?curid=979229 |
Philipp Ludwig Statius Müller (April 25, 1725 – January 5, 1776) was a German zoologist. Statius Müller was born in Esens, and was a professor of natural science at Erlangen. Between 1773 and 1776, he published a German translation of Linnaeus's "Natursystem". The supplement in 1776 contained the first scientific class... | https://en.wikipedia.org/wiki?curid=981615 |
William Ogilby (1808–1873) was an Irish barrister and naturalist. Ogilby was honorary secretary of the Zoological Society of London from 1839 to 1846. | https://en.wikipedia.org/wiki?curid=981797 |
L ring The L-ring of the bacterial flagellum is the ring in the lipid outer cell membrane through which the axial filament (rod, hook, and flagellum) passes. | https://en.wikipedia.org/wiki?curid=983400 |
NGC 3 is a lenticular galaxy in the Pisces constellation. It was discovered on November 29, 1864 by Albert Marth. | https://en.wikipedia.org/wiki?curid=983406 |
NGC 5078 is a spiral galaxy in the Hydra constellation, approximately 94 million light-years away from Earth. It has a diameter of 127,000 light-years and is probably a member of the NGC 5061 group. The dust lane of is warped, probably by interaction with the nearby galaxy IC 879, which is itself distorted into an 'S' ... | https://en.wikipedia.org/wiki?curid=983463 |
Clay Riddell Clayton Howard Riddell, OC (July 13, 1937 – September 15, 2018) was a Canadian billionaire businessman who was the founder, president and CEO of Paramount Resources, based in Calgary, Alberta. He was born on a farm near Treherne, Manitoba on July 13, 1937, the youngest child of Cecil Howard Riddell and Ber... | https://en.wikipedia.org/wiki?curid=983668 |
Clay Riddell He was married to Vi Thorarinson, a nurse for 49 years until her death from leukemia in 2012. They had three daughters and a son together, Lynne, Sue, Jim and Brenda. Riddell died on September 15, 2018, after a short illness. | https://en.wikipedia.org/wiki?curid=983668 |
Sol (colloid) A sol is a colloid made out of very small solid particles in a continuous liquid medium. Sols are quite stable and show the Tyndall effect. Examples include blood, pigmented ink, cell fluids, paint, antacids and mud. Artificial sols may be prepared by dispersion or condensation. Dispersion techniques incl... | https://en.wikipedia.org/wiki?curid=991054 |
NGC 7320 is a spiral galaxy in the Stephan's Quintet. However, it is not an actual member of the galaxy group, but a much closer line-of-sight galaxy at a distance of about 40 million light years. Other galaxies of Stephan's Quintet are some 300 million light-year distant. | https://en.wikipedia.org/wiki?curid=992044 |
Earth (historical chemistry) Earths were defined by the Ancient Greeks as "materials that could not be changed further by the sources of heat then available". Several oxides were thought to be earths, such as aluminum oxide and magnesium oxide. It wasn't until 1808 that these weren't elements but metallic oxides. | https://en.wikipedia.org/wiki?curid=992733 |
Orbiting body In astrodynamics, an orbiting body is any physical body that orbits a more massive one, called the primary body. The orbiting body is properly referred to as the secondary body (formula_1), which is less massive than the primary body (formula_2). Thus, formula_3 or formula_4. Under standard assumptions in... | https://en.wikipedia.org/wiki?curid=996828 |
Relative angular momentum In celestial mechanics, the relative angular momentum (formula_1) of an orbiting body (formula_2) relative to a central body (formula_3) is the moment of (formula_2)'s relative linear momentum: where: For a body in an unperturbed orbit about a central body, the orbital plane is stationary, and... | https://en.wikipedia.org/wiki?curid=997253 |
Bioequivalence is a term in pharmacokinetics used to assess the expected in vivo biological equivalence of two proprietary preparations of a drug. If two products are said to be bioequivalent it means that they would be expected to be, for all intents and purposes, the same. Birkett (2003) defined bioequivalence by sta... | https://en.wikipedia.org/wiki?curid=998103 |
Bioequivalence The United States Food and Drug Administration (FDA) has defined bioequivalence as, "the absence of a significant difference in the rate and extent to which the active ingredient or active moiety in pharmaceutical equivalents or pharmaceutical alternatives becomes available at the site of drug action whe... | https://en.wikipedia.org/wiki?curid=998103 |
Bioequivalence In addition to data from bioequivalence studies, other data may need to be submitted to meet regulatory requirements for bioequivalence. Such evidence may include: The World Health Organization considers two formulation bioequivalent if the 90% confidence interval for the ratio multisource (generic) prod... | https://en.wikipedia.org/wiki?curid=998103 |
Bioequivalence The FDA considers two products bioequivalent if the 90% CI of the relative mean C, AUC and AUC of the test (e.g. generic formulation) to reference (e.g. innovator brand formulation) should be within 80% to 125% in the fasting state. Although there are a few exceptions, generally a bioequivalent compariso... | https://en.wikipedia.org/wiki?curid=998103 |
Bioequivalence com and The People's Pharmacy, released the results of comparative tests of different brands of bupropion. The People's Pharmacy received multiple reports of increased side effects and decreased efficacy of generic bupropion, which prompted it to ask ConsumerLab.com to test the products in question. The ... | https://en.wikipedia.org/wiki?curid=998103 |
Bioequivalence As a result, 30 products were removed from US markets and Ranbaxy paid $500 million in fines. The FDA investigated many Indian drug manufacturers after this was discovered, and as a result at least 12 companies have been banned from shipping drugs to the US. | https://en.wikipedia.org/wiki?curid=998103 |
Tuberous receptor Tuberous receptors are electroreceptors that are specialized to respond to high-frequency electrical fields (electric organ discharges or EODs), and hence are found only in fish with an active electrical sense that can generate their own electrical fields. They are mostly found on weakly electric fish... | https://en.wikipedia.org/wiki?curid=1005964 |
Biorobotics is an interdisciplinary science that combines the fields of biomedical engineering, cybernetics, and robotics to develop new technologies that integrate biology with mechanical systems to develop more efficient communication, alter genetic information, and create machines that imitate biological systems. Cy... | https://en.wikipedia.org/wiki?curid=1006293 |
Biorobotics Today, it covers all scientific fields with system related processes. The goal of cybernetics is to analyze systems and processes of any system or systems in an attempt to make them more efficient and effective. Cybernetics is used as an umbrella term so applications extend to all systems related scientific... | https://en.wikipedia.org/wiki?curid=1006293 |
Biorobotics There are three main techniques used in genetic engineering: The plasmid method, the vector method and the biolistic method. This technique is used mainly for microorganisms such as bacteria. Through this method, DNA molecules called plasmids are extracted from bacteria and placed in a lab where restriction... | https://en.wikipedia.org/wiki?curid=1006293 |
Biorobotics In the medical field, genetically modified bacteria are used to produce drugs such as insulin, human growth hormones and vaccines. In research, scientists genetically modify organisms to observe physical and behavioral changes to understand the function of specific genes. In agriculture, genetic engineering... | https://en.wikipedia.org/wiki?curid=1006293 |
Biorobotics He found that electrical stimulation could restore hearing by inserting an electrical implant to the saccular nerve of a patient’s ear. In 1945, the National Academy of Sciences created the Artificial Limb Program, which focused on improving prosthetics since there were a large number of World War II ampute... | https://en.wikipedia.org/wiki?curid=1006293 |
Biorobotics Externally-powered prosthetics consist of motors to power the prosthetic and buttons and switches to control the prosthetic. Myoelectrically-powered prosthetics are new, advanced forms of prosthetics where electrodes are placed on the muscles above the limb. The electrodes will detect the muscle contraction... | https://en.wikipedia.org/wiki?curid=1006293 |
Biorobotics This artificial sensing skin detects any pressure put on it and is meant for people who have lost any sense of feeling on parts of their bodies, such as diabetics with peripheral neuropathy. The bionic eye is a bioelectronic implant that restores vision for people with blindness. Orthopedic bionics consist ... | https://en.wikipedia.org/wiki?curid=1006293 |
Arthur Urquhart Arthur Torrane Urquhart (1839–1919) was an arachnologist and naturalist based in New Zealand. Urquhart was born in Switzerland in 1839. In 1856, he migrated to New Zealand and lived in a farm in Karaka. He produced eighteen taxonomic papers between 1882 and 1897. | https://en.wikipedia.org/wiki?curid=62040174 |
NGC 4380 is a spiral galaxy located in the constellation of Virgo . | https://en.wikipedia.org/wiki?curid=62056938 |
Osebury Rock (also spelt Oseberrow or Rosebury) is a cliff on the River Teme where fragmentary rocks of the Haffield Breccia layer are revealed. Its woodland and vegetation include some restricted varieties including the large-leaved lime and narrow-leaved bitter-cress. It was registered as a Site of Special Scientific... | https://en.wikipedia.org/wiki?curid=62060919 |
Richard Heaton (priest) Richard Heaton, DD was a Church of Ireland priest in Ireland during the Seventeenth Century. Heaton was educated at Trinity College, Dublin. He was appointed Prebendary of Kilrush in Killaloe Cathedral in 1633 and Dean of Clonfert in 1662, holding both positions until his death in 1666. He was a... | https://en.wikipedia.org/wiki?curid=62067487 |
Stephen Eales is a professor of astrophysics at Cardiff University, where he is currently head of the Astronomy Group. In 2015, he was awarded the Herschel Medal from the Royal Astronomical Society for outstanding contributions to observational astrophysics. He also writes articles and books about astronomy. His main r... | https://en.wikipedia.org/wiki?curid=62067518 |
Vicarious Hypothesis The Vicarious Hypothesis, or hypothesis vicaria, was a planetary hypothesis proposed by Johannes Kepler to describe the motion of Mars. The hypothesis adopted the circular orbit and equant of Ptolemy's planetary model as well as the heliocentrism of the Copernican model. Calculations using the did ... | https://en.wikipedia.org/wiki?curid=62081079 |
Vicarious Hypothesis Nicolaus Copernicus broke from the geocentric model of Ptolemy by placing the Sun at the center of his planetary model. However, Copernicus retained circular orbits for the planets and added an orbit for the Earth, insisting that the Earth revolved around the Sun. The Sun was positioned off-center ... | https://en.wikipedia.org/wiki?curid=62081079 |
Vicarious Hypothesis Using these positions for the Sun and equant, the model constructed using the agreed with the twelve observations within 2' of arc, a level of accuracy better than any other previous model. While the heliocentric longitudes of this model proved to be accurate, distances from the Sun to Mars, or lat... | https://en.wikipedia.org/wiki?curid=62081079 |
Vicarious Hypothesis He used calculations previously made with the to confirm the elliptical orbit for Mars. Kepler published his results in "Astronomia Nova", in which he introduces the elliptical orbit for planets as his first law of planetary motion. | https://en.wikipedia.org/wiki?curid=62081079 |
Anthropocene Working Group The (AWG) is an interdisciplinary research group dedicated to the study of the Anthropocene as a geological time unit. It was established in 2009 as part of the Subcommission on Quaternary Stratigraphy (SQS), a constituent body of the International Commission on Stratigraphy (ICS). As for 201... | https://en.wikipedia.org/wiki?curid=62084284 |
Anthropocene Working Group " Later in 2002, Crutzen published a commentary on "Nature" titled "Geology of Mankind" where he further stressed the idea "to assign the term ‘Anthropocene’ to the present, in many ways human-dominated, geological epoch, supplementing the Holocene," with starting date in the late 18th centur... | https://en.wikipedia.org/wiki?curid=62084284 |
Anthropocene Working Group In 2009, the Subcommission on Quaternary Stratigraphy established an to "examine the status, hierarchical level and definition of the Anthropocene as a potential new formal division of the Geological Time Scale." Some authors have labelled this moment as 'stratigraphic turn' or 'geological tu... | https://en.wikipedia.org/wiki?curid=62084284 |
Anthropocene Working Group As for most of the epochs in the Phanerozoic (the current Eon, starting 541 million years ago), determining the beginning of the Anthropocene by locating and agreeing upon its lower boundary is a necessary step in its process of formalization. A lower boundary is defined by locating a GSSP (i... | https://en.wikipedia.org/wiki?curid=62084284 |
Anthropocene Working Group In January 2014, the Geological Society of London published "A Stratigraphical Basis for the Anthropocene," a collection of scientific essays dedicated to assessing and analyzing the anthropogenic signatures defining the Anthropocene, and its requirements to be recognized as a distinct chrono... | https://en.wikipedia.org/wiki?curid=62084284 |
Anthropocene Working Group In May, 2019, the AWG completed a binding vote determining two major research questions: Both questions received a positive response, with 29 votes in favor, 4 votes against, and no abstention (33 votes received out of 34 potential voting members). | https://en.wikipedia.org/wiki?curid=62084284 |
Genome sequencing of endangered species is the application of Next Generation Sequencing (NGS) technologies in the field of conservative biology, with the aim of generating life history, demographic and phylogenetic data of relevance to the management of endangered wildlife. In the context of conservation biology, geno... | https://en.wikipedia.org/wiki?curid=62084317 |
Genome sequencing of endangered species In some cases those methods led to great results, but some problems still remain. For example, by inbreeding only few individuals, the genetic pool of a sub-population remains limited or may decrease. Genetic analyses can remove subjective elements from the determination of the p... | https://en.wikipedia.org/wiki?curid=62084317 |
Genome sequencing of endangered species While solving biological problems, one encounters multiple types of genomic data or sometimes an aggregate of same type of data across multiple studies and decoding such huge amount of data manually is unfeasible and tedious. Therefore, integrated analysis of genomic data using s... | https://en.wikipedia.org/wiki?curid=62084317 |
Genome sequencing of endangered species For example, in the case of amphibians, there are multiple transitions among male and/or female heterogamety. Sometimes even variation of sex chromosomes within amphibian populations of the same specie were reported. The multiple transitions among XY and ZW systems that occur in ... | https://en.wikipedia.org/wiki?curid=62084317 |
Genome sequencing of endangered species A recent study used whole-genome sequencing data to demonstrate the sister lineage between the Dryas monkey and vervet monkey and their divergence with additional bidirectional gene flow approximately 750,000 to approximately 500,000 years ago. With <250 remaining adult individua... | https://en.wikipedia.org/wiki?curid=62084317 |
Genome sequencing of endangered species The RNA extraction is essential for the transcriptome assembly and the extraction process start from stem, roots, fruits, buds and leaves. The "de novo" genome assembly can be performed using software to optimize assembly and scaffolding. The software can also be used to fill the... | https://en.wikipedia.org/wiki?curid=62084317 |
Genome sequencing of endangered species The ongoing development of cheaper and high throughput allowed the production of a wide array of information in several disciplines providing conservation biologists a very powerful databank from which was possible to extrapolate useful information about, for example, population ... | https://en.wikipedia.org/wiki?curid=62084317 |
Genome sequencing of endangered species For these reasons several alternative strategies where developed: constant monitoring, for example with radio collars, allow us to understand the behaviour and develop strategies to obtain genetic samples and management of the endangered populations. The samples taken from those ... | https://en.wikipedia.org/wiki?curid=62084317 |
Kurt Lohwag (1913 – 1970) was a Bohemian-born Austrian botanist and mycologist. The son of the mycologist Heinrich Lohwag, he was educated at the University of Vienna. For much of his career, he worked at the Hochschule für Bodenkultur, Vienna. | https://en.wikipedia.org/wiki?curid=62088523 |
Marta Catellani is an Italian chemist known for her discovery of the eponymous Catellani reaction in 1997. She was elected to the European Academy of Sciences in 2016. Catellani earned her Ph.D. in chemistry in 1971 from the University of Parma, where, as of 2019, she is a professor and chairs the Department of Organic... | https://en.wikipedia.org/wiki?curid=62096452 |
Katarina Cicak is a physicist. She is a researcher in the advanced microwave photonics group at the National Institute of Standards and Technology. | https://en.wikipedia.org/wiki?curid=62115342 |
Prime editing is a ‘search-and-replace’ genome editing technology in molecular biology by which the genome of living organisms may be modified. The technology directly writes new genetic information into a targeted DNA site. It uses a fusion protein, consisting of a catalytically impaired Cas9 endonuclease fused to an ... | https://en.wikipedia.org/wiki?curid=62129266 |
Prime editing This results in a branched intermediate that contains two DNA flaps: a 3’ flap that contains the newly synthesized (edited) sequence, and a 5’ flap that contains the dispensable, unedited DNA sequence. The 5’ flap is then cleaved by structure-specific endonucleases or 5’ exonucleases. This process allows ... | https://en.wikipedia.org/wiki?curid=62129266 |
Prime editing Despite its increased efficacy, the edit inserted by PE2 might still be removed due to DNA mismatch repair of the edited strand. To avoid this problem during DNA heteroduplex resolution, an additional single guide RNA (sgRNA) is introduced. This sgRNA is designed to match the edited sequence introduced by... | https://en.wikipedia.org/wiki?curid=62129266 |
Prime editing The prime system introduces single-stranded DNA breaks instead of the double-stranded DNA breaks observed in other editing tools, such as base editors. Collectively, base editing and prime editing offer complementary strengths and weaknesses for making targeted transition mutations. Base editors offer hig... | https://en.wikipedia.org/wiki?curid=62129266 |
Prime editing As of 2019, prime editing looks promising for relatively small genetic alterations, but more research needs to be conducted to evaluate whether the technology is efficient in making larger alterations, such as targeted insertions and deletions. Larger genetic alterations would require a longer RT template... | https://en.wikipedia.org/wiki?curid=62129266 |
Prime editing 3kb, which doesn't even account for the lengthened guide RNA necessary for targeting and priming the site of interest. Images created with Biorender. | https://en.wikipedia.org/wiki?curid=62129266 |
Elsa Matilde Zardini (born 1949) is an Argentinian/Paraguayan botanist, teacher, curator, and explorer. She has made botanical expeditions in the US, Brazil, Argentina, Paraguay. Three botanical taxon names were authored by Zardini. Her specialization is the flora of the Plata basin, with an emphasis on that of Paragua... | https://en.wikipedia.org/wiki?curid=62132271 |
Thierry Chopin Thierry B.R. Chopin is a phycologist and professor of aquaculture at the University of New Brunswick, Saint John. | https://en.wikipedia.org/wiki?curid=62134509 |
3MM-1 is a star-forming galaxy about 12.5 billion light-years away that is obscured by clouds of dust. It was first detected in spectroscopic data on rotational transitions of carbon monoxide obtained using the Atacama Large Millimeter Array from 23-24 December 2018, as detailed in an article that was published on 22 O... | https://en.wikipedia.org/wiki?curid=62134998 |
John Diffley (biologist) John Francis Xavier Diffley (born 1958 in New York City) is a molecular biologist who specializes in studying eukaryotic DNA replication. He was awarded the 2019 Canada Gairdner International Award for his "pioneering research on the eukaryotic DNA replication cycles including initiation, regul... | https://en.wikipedia.org/wiki?curid=62145523 |
Victoria Leong is a developmental cognitive neuroscientist whose research into the neural synchrony between mothers and infants has been widely reported. Leong's PhD thesis won the Robert J. Glushko Prize of the Cognitive Science Society in 2014 "in recognition of outstanding cross-disciplinary work integrating neurosc... | https://en.wikipedia.org/wiki?curid=62165769 |
Sebeș Formation The is a geological formation in Romania. It is of Maastrichtian age. It is laterally equivalent to the Sard Formation. The base of the formation consists of claystones interbedded with sandstones and conglmerates. It is well known for its fossils which form a component of the Hațeg Island fauna. | https://en.wikipedia.org/wiki?curid=62168119 |
Glacier head A glacier head is the top of a glacier. Although glaciers seem motionless to the observer they are in constant motion and the terminus is always either advancing or retreating. On a glacier, the accumulation zone is the area above the firn line, where snowfall accumulates and exceeds the losses from ablati... | https://en.wikipedia.org/wiki?curid=62175198 |
Glacier head "attribution":Contains text copied from Accumulation zone and Bergschrund and Terminus. | https://en.wikipedia.org/wiki?curid=62175198 |
NGC 4746 is an edge-on spiral galaxy located 107 million light-years away in the constellation Virgo. It was discovered by John Herschel during a sky-survey on March 29, 1830. | https://en.wikipedia.org/wiki?curid=62176999 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.