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In addition, previous evidence indicated that higher expression of SIRT1 upregulated antiapoptotic proteins Bcl-2 and Bcl-xl, downregulated proapoptotic protein Bax, then increases cell viability in ischemia-reperfused myocardium [15].
background
4. Discussion
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A common characteristic of HFpEF observed in our model is a reduction in cardiac reserve (Tan et al. 2009; Norman et al. 2011; Marshall et al. 2013).
background
Discussion
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Similar mechanisms are found during neuronal subtype development in the Drosophila ventral nerve cord [17].
background
Discussion
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196b889f81e2b36b541407019f47b05fb1f0cd59
Free-field stimuli were simulated by filtering signals through head-related transfer functions (HRTFs) measured in one cat by Musicant et al. (1990).
method
2. Methods
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Several papers have found that past subsidies significantly expanded demand for solar systems (Hughes and Podolefsky, 2015; Burr, 2016; De Groote and Verboven, 2016; Gillingham and Tsvetanov, 2017).
background
1 Introduction
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…without the express permission from Emerald Group Publishing Limited. culturally dominant processing style (holistic or analytic thinking) (Nisbett et al., 2001), thinking styles can be viewed as a within-culture individual difference or can vary by the specific situation (e.g., Choi et…
background
Role of Holistic Thinking
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…carriage rate was 4.4%, which is in close agreement with that reported by Hisata et al. (2005), accounting for 2.3% more than the values mentioned in the study carried out by Torano et al. (2001) in La Habana, Cuba, 3.1% more than those of a study conducted in Brazil (Cardoso-Lamaro et al., 2009).
result
4. Discussion
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For power calculation in the linear regression analysis, we considered the magnitude of the gene-environment interaction, and according to Luan et al [50] an interaction was considered to be relevant in magnitude when the ratio of the two regression slopes [B1 for the genetic variable as additive in the first versus th...
method
Methods
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…in the natal burrow (Hare & Murie 1996) and only littermate kin appear to act as ‘genial neighbours’ providing direct and indirect fitness benefits (Viblanc et al. 2010; Dobson et al. 2012). data analyses To investigate the effects of individual kin on energy allocation strategies and fitness,…
background
Materials and methods
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[4] have recently proposed a scheme for an entanglement amplifier based on a nondegenerate three-level laser when the three-level atoms are injected at the lower level and the top and bottom levels are coupled by a strong coherent light.
background
1. Introduction
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maticity, refractoriness and conduction of the heart are conserved between zebrafish and humans [44, 46].
background
Discussion
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Specifically, our findings confirm the study hypothesis that a high tendency to forgive is associated with a reduction in PTSD symptoms, as demonstrated in previous findings (Heinze and Snyder 2001; Kaminer et al. 2001; Witvliet et al. 2004; Friedberg et al. 2005; Snyder and Heinze 2005; Hamama-Raz et al. 2008; Weinber...
result
Discussion
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Several studies retrospectively examine underage entry of females into the sex trade (Cobbina & Oselin, 2011; Goldenberg et al., 2014), but few neither include actively underage sex workers nor examine their social and structural HIV risks.
background
Introduction
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Integrate the spectral and spatial information with the time component provides rich information to detail the space variations along the time [Petitjean et al., 2012] and can provide pattern observations, which are not found in single time observations, such as trends and periodicities [Kuenzer…
background
1. Introduction
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But, solutions to semantic problems are scarce and either require domain knowledge [24, 18, 4, 19] or provide a specific technique [15].
background
5 Related work
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Analysis of variance for repeated measurements (ANOVA) was performed to assess the significance of differences in means between and within the groups and post-hoc analysis with the Tukey method was performed if any position effects and ⁄ or position-group interactions proved significant by ANOVA [6].
method
Methods
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Our results provide guidance to clinicians and patients as they demonstrate that the changes in bleeding and/or spotting days observed following insertion of the LNG-IUS in women with HMB follows a similar pattern to that observed in women using the intrauterine system for contraception [1,4,5,21], except that women wi...
result
4. Discussion
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By contrast, the spider monkey has been described as a fruit specialist (Di Fiore et al. 2008; González-Zamora et al. 2009).
background
Methods
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Although, this sophisticated defence system is weakened with advancing age and even in the absence of overt lung disease [26–31], the intrathoracic dwell time of influenza viruses is increased [29, 32] facilitating any transepithelial migration of the viral particles.
background
2.1. The Nonimmune Specific Mechanisms That Facilitate
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…used routinely to survey for squid of commercial interest (Jefferts et al. 1987, Goss et al. 2001), but it has been debated whether toothed whales are able to detect squid (Fristrup & Harbison 2002) using echolocation clicks of shorter duration and broader bandwidth (Au 1993, Madsen et al. 2004).
background
RESULTS
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The recommended medium for HUES-7 is HUES-C (see Table 1; Cowan et al., 2004), which differs significantly from BG-SK medium.
background
Results
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Invasive species that cause extinction of native species will ultimately reduce local and global species diversity (Vitousek et al. 1996; Mooney & Cleland 2001; Collins et al. 2002).
background
2dda28049d7f05f453f484a248f5a77d75efaa8b
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To control for spatial attention modulation that could be synchronous with stimulus presentation, we required the subjects to perform a visual task superimposed on the fixation square during the entire duration of the scan (Beauchamp et al., 1997; Kastner et al., 1998; Somers et al., 1999; Tootell et al., 1998).
method
Methods
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as D90HR CTV (the dose covering 90% of the highrisk clinical target volume) for tumors and D2cc (the minimum dose in the 2cc most irradiated tissue volume) for OAR, have been demonstrated to be predictive of the tumor control probability and occurrence of LSE for OAR [1, 2, 8].
background
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Furthermore, GFP-ATG16L1 precipitated mCherryTMEM74 and endogenous TMEM74 (Figure 2e), conversely, GFP-ATG16(1-320) failed to bindmCherry-TMEM74 (Figure 2f), suggesting that the WD repeats domain of ATG16L1 was required for the interaction with TMEM74.
background
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The position of the inserted PE tube was adjusted such that flow-limitation was reflected in the measured Pn [3, 28].
background
Negative Pressure − Inspiration
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The isolation procedure was performed according to the methods used by Xue et al. (2013) [10] and Wang et al. (2015) [11].
method
2. Methods
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N-cadherin was isolated as described (Bixby and Zhang, 1990), and SDS-PAGE protocols have been described (Bixby and Reichardt, 1985).
method
Methods
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DNA damage resulting from TNP induced oxidative stress leads to the activation of p53[2-5,29,44,53,54], which triggers cell cycle arrest to prevent proliferation of cells with damaged DNA and ensure genomic stability[55].
background
1. DNA damage and p53 upregulation
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We model the breeding attempt as a two-step sequential game, following Smith and Härdling (2000) and Savage et al.
method
Methods
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The SR by Bhutta et al (13) was ruled out because it included studies up to 1999, and of the 3 remaining SRs, the 2 most recent were more comprehensive, and of both, the Cochrane JPGN Volume 60, Number 4, April 2015 authorized reproduction of this article is prohibited. publication by Lazzerini and Ronfani (14) was ...
method
METHODS
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CD47 is expressed widely in both hematopoietic cells, including three subtypes of cDCs (Supplemental Figure S3), and nonhematopoietic cells, however.(20,24) We therefore next For personal use only.
background
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2 In addition to these spatio-temporal and socio-demographic dynamics, work in GDTs is also affected by teams’ geographic configuration, which O’Leary and Cummings (2007) define as the number of geographically dispersed sites and the relative number of team members at those sites, independent of…
background
Introduction
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…of the HD-Zip I and II families function as developmental regulators, specifically being involved in regulation of developmental adaptation to environmental stress conditions (e.g. Meijer et al. 1997; Lee and Chun 1998; Scarpella et al. 2000, 2002; Manavella et al. 2006; Komatsuda et al. 2007).
background
Discussion
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510ee3954bbebad58110c1d1376cafc70581ec0d
Others (Zigler and Lessios 2003; McCartney and Lessios 2004; Lessios 2007) have suggested that the pattern is more likely the product of what Templeton (1981) and Noor (1999) have called ‘‘differential fusion,’’ that is, the higher probability that species with differentiated reproductive…
background
Introduction
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Also, genes involved in PS II and the light harvesting complex were down-regulated by mild drought at the DZ and TZ1, which is in line with the observation that drought stress results in damage to PS II and photochemistry in mature leaves (Lu and Zhang, 1999; Sperdouli and Moustakas, 2012).
background
Discussion
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The erythropoietic growth factors affect the progenitors in all these locations [3], and many procedures have been undertaken to reproduce the erythroid maturation in vitro including initial selection of the CD34+ cells [7–11], adherence depletion [1,3,12,13] and phased culturing [6,12,14].
method
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Model calculations overpredicted the OH concentrations (Mao et al., 2009), particularly at altitudes less than 2 km, but found the overprediction to correlate with HCHO concentrations, indicating missing reactive VOCs in the model (Mao et al., 2009).
background
1 Introduction
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Transcripts containing the four noncoding exons are expressed in multiple regions of the mouse brain and nervous system, indicating that they do not determine distinct expression domains (Drews et al. 2005).
background
Results
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73f36294b5992a53e4f075e384fe30a13c629bb4
…extends previous work that has shown that certain aspects of gait may depend on cognitive function and attention (Springer et al. 2006; Woollacott and Shumway-Cook 2002; Yogev et al. 2005; Bloem et al. 2001; Morris et al. 1996; Auriel et al. 2006; Van Wegen et al. 2006; Verghese et al. 2002).
background
Discussion
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8d588720ea1b676f8b3906b696e06cf64f5b766b
…between output and input, CNF achieves almost 10% relative improvement over CRF. CNF also outperforms other methods including SVMpro (Hua and Sun, 2001), SVMpsi (Kim and Park, 2003), YASSPP (Karypis, 2006), PSIPRED (Jones, 1999), SPINE (Dor and Zhou, 2007) and TreeCRFpsi (Dietterich et al., 2004).
method
5.2 Methods
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This is consistent with the former research result that NSPEs reduce the amount of pathological bacteria within the small intestine by lowering the viscosity of intestinal digesta [11].
result
Discussion
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we take one real DHT system Kad [1] as a case for study, which is the first widely-deployed Kademlia-based [17] DHT file-sharing system.
method
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Simulations of the beam-type specimens (Chen, 2001; Peters et al., 2002) were able to capture the stresses measured in the experiments.
background
4.2. Cracking at low applied load ratio
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(7) investigated BNP for the diagnosis of acute lung injury in a different cohort of intensive care patients, those having acute pulmonary edema.
method
Results
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Previous studies described that ectopic miR-99a expression slowed keratinocyte growth and liver cancer cell growth by blocking the cell cycle at the G1/S transition [10,29].
background
Discussion
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d6eaf36357406cc26c09d36fc88d8974ba49807d
The composite maps were generated through further development of previously reported navigation [Kinsey and Whitcomb, 2004] and sonar processing routines [Ballard et al., 2000; Whitcomb et al., 2000; Singh et al., 2000], and are nested within the existing ABE bathymetry data collected at 9 500N [Yoerger et al.
method
1.1. Ridge Crest Setting
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We incorporated HF remodeling of the electromechanical tissue properties in the MRI-based geometric model of failing canine ventricles, as previously described (9).
method
METHODS
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Although extensive research have been carried out on testing the ISSM [16–19], little study [6] exists which explores the success of ePortfolios by leveraging ISSM as a theoretical underpinning.
background
Introduction
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A closely related analogue of CGP78850, CGP85793, prevented sperm capacitation and increase in P-Tyr (de Lamirande and Gagnon, 2002), again emphasizing the difference in the regulation between this process and AR.
background
Discussion
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Our data also showed that lesions in the head and neck region responded better to PDL therapy than in other regions; similar results were reported by several studies [16, 24–28].
result
Discussion
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However, we did not observe any association of maternal free thyroxine with child neurodevelopmental outcomes, agreeing with the Project Viva results (11) but not with those of other studies (8–10, 43).
result
DISCUSSION
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was coined to synthesize how humanoid robots and computational neuroscience could contribute to progresses in naturalizing human psychology and the underlying neurophysiology (Asada et al., 2001; Brooks, 1997; Cheng et al., 2007; Kawato, 2008).
background
1. Introduction
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The method Gordian [30] has been the most successful analytic placer that can handle large design instances [30, 34, 15, 60, 43, 32, 2, 63].
method
Method
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, 2006), and there are many examples of studies examining the adoption of mobile technology and mobile services (Balocco et al., 2009; Kim and Garrison, 2009; Liang et al., 2007), to the best of the authors’ knowledge, this is the first study to combine these two perspectives in an attempt to understand how sales force...
background
1. Introduction
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, 2005) and the two remaining studies were pseudo-randomized controlled studies (Colpi et al., 2009; Ghalayini et al., 2011); these last two studies were randomized based on the waiting list for the operative theatre.
background
RESULTS
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cells expressed CD7 in coculture with OP9 stroma cells in the absence of IL-7 and in the presence of IL-15 conditioning [(2) NL/(2)IL-7(+)IL-15].
background
Results
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The transfection method using adenovirus conjugated to poly-L-lysine and the techniques used to expose cells to laminar shear stress with the use of a parallel-plate shear chamber and flow loop have been described elsewhere (15).
method
MATERIALS AND METHODS
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…plays a minimal role, because IFN-γ is unable to induce its nuclear translocation (Blanchette et al., 2003; Shenet al., 2005); others indicate that, byactivating Jak/STATindependent pathways, IFN-γ induces the nuclear translocation of both NF-κB and IRF-1 (Kim et al., 2004; Park et al., 2005).
background
1. Introduction
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Our classification of comorbidities was also dependent on coded data, which may have inaccuracies but is unlikely to be differentially distributed between RA and non-RA cases, and therefore unlikely to introduce systematic bias into the results [27].
background
Discussion
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Next, the tumor area in the patient can either be delineated manually or using classification methods on multi-modal magnetic resonance (MR) images as shown in (199).
method
5.2.3 Methods
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Whether Arctic clouds have a net warming or cooling effect depends on the time of year and location (Garrett et al., 2002; Garrett and Zhao, 2006; Lubin and Vogelmann, 2007; Sedlar et al., 2010; Shupe and Intrieri, 2004; Tjernström, 2005; Wang and Key, 2003).
background
1 Introduction
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9: Mobivisit project, Screenshots of the mobile museum guide, Museum of Fine Arts, Lyon (Damala et al., 2005) -
background
2.4.4 DESCRIPTION OF THE GUIDE AND NAVIGATION SCHEME
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Group 3: mice were anesthetized in a Plexiglas chamber with 3% isoflurane in air for 25 min (after the desired concentration was reached) twice daily, as described previously (12); 0.
method
Methods
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The reciprocating single file systems such as Reciproc (VDW, Munich, Germany) and WaveOne (Maillefer, Ballaigues, Switzerland) provides more flexibility of the M‐wire Ni‐Ti alloy, greater resistance to cyclic fatigue and better handling of narrow and curved canals than the traditional Ni‐Ti instruments and they are wid...
background
INTRODUCTION
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Because of the inherent lack of scalability in floodbased schemes, researchers have looked at several hierarchical and structured approaches [12][11].
background
1. Introduction
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A large number of possible routes can exist between any two compounds, particularly those that feature in multiple pathways, and so tools such as KEGG PathComp [6] have been created to automatically perform these searches quickly and efficiently.
method
1. Background
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It has been reported that NF-κB activation can induce expression of Bcl-2 protein, thereby inhibit apoptosis.((33)) However, our results documented that HQH could attenuate adriamycin-induced cellular apoptosis, while NF-κB signaling was inhibited.
result
DISCUSSION
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[24,25] However, planar I-131 imaging has traditionally suffered from low resolution, and a paucity of anatomic information along with a long list of physiologic variants makes image interpretation challenging.[26] Therefore, it is assumed that the reason why functioning ETT in TGDR has been underestimated in patients ...
background
DISCUSSION
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Treatment with the general myosin inhibitor 2,3-butanedione monoxime (BDM) (Radford and White, 2011) reduced the number of flg22-induced FLS2-GFP endosomes by ;80% compared with the control.
background
RESULTS
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IFN-alpha as a biological response modiWer showed modest activity against NMIBC [17].
background
BCG–IFN in BCG failures
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The development and test sets are from WMT 2006 shared task.1 The evaluation metric is case-insensitive BLEU (Papineni et al., 2002) as calculated by the multi-bleu.perl script.
method
4.1 Setup
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Disadvantages include those described above for DNA (if this is the PCR target, although disadvantage d would not apply) or RNA (if reversetranscriptase PCR is used), plus the unknown yet potentially variable amplification efficiencies of different target sequences (Suzuki & Giovannoni, 1996).
background
Quantitative community structure
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For example, personality disorders have been reported to be significant predictors of low scores across a range of subscales on the SF-12 [8], including mental health, social functioning and role impairment due to emotional problems [9, 10].
background
Introduction
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The novel speckle correlation analysis method is proposed for evaluating the degree of coherence (DOC), by modifying the previously proposed theory [8] and adapting it to the standard phase modulator configuration.
method
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CYLD was catalytically deficient when tested with TRAF2/ 6 as substrates (4); and consistently, it increased IkBaphosphorylation and NF-kB gene reporter function (Supplementary Fig.
method
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(Unfortunately, many later references to Trivers (1971) do not clearly distinguish reciprocal helping from cooperation in the narrow sense and from exchange among not particularly needy individuals.)
background
Implications for Explaining Cooperation: Towards a Classification in Terms of Psychological Mechanisms
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…(Aldehni et al., 2003), glnN displays an imperfect NtcAbinding motif and a negatively acting cis-element in the upstream region of its promoter (Aldehni & Forchhammer, 2006), and nblA has a complex regulatory region containing multiple promoters: under nitrogen deprivation, its major promoter…
background
DISCUSSION
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also reported that IL-6 caused growth impairment through a decrease in IGF-1 in IL-6 transgenic mice under the control of neurospecific enolase promoter (46).
background
Discussion
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Instead of using the single fuzzless locus mutant developed mapping populations (Rong et al. 2005, 2007; Zhang et al. 2005; Guo et al. 2006; Wan et al. 2007), the common female parent line of the two F2 populations we developed combined at least two fuzzless loci (N1 and n2, and probably n3)…
background
Discussion
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For example, studies of genetic correlations in Drosophila frequently report positive correlations among most traits measured (Cowley and Atchley 1990; Wilkinson et al. 1990; Norry et al. 1997).
background
INTRODUCTION
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Hearing loss and tinnitus have been linked, both pathophysiologically (Eggermont and Roberts, 2004; Jastreboff, 1990) and clinically (De Ridder et al., 2015a; Norena et al., 2002; Schecklmann et al., 2012b).
background
Discussion
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Renal transplants in these pairs were performed as previously described.(17) All recipients received induction with 0.
method
Methods
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On contrary to our results, Huang et al. (2006) studied 150 Chinese patients with SLE and 130 unrelated healthy individuals living in central Taiwan as control subjects. There were no statistically significant differences in IL-6 and IL-8 gene polymorphisms between the SLE and control groups (p=0.53 and p=0.44, respect...
result
Discussion
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Up to now, no role for FGF signaling in aVE induction has been described, however, Fgf8b was found to be important for the correct positioning of the aVE (Guo and Li, 2007).
background
Results
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Our observations are compatible with those of Verdijk et al, who expressed an N-terminal cytoplasmic GFP-tagged Langerin mutant in human fibroblastic cells [26].
result
Discussion
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The occurrence of burst suppression in this study contrasts with EEG studies in humans, rats and horses in which no burst suppression was reported over the range 0.6–1.75 MAC halothane (Johnson et al. 1994; Thomsen & Prior 1996; Johnson & Taylor 1998; Antunes et al. 2003; Murrell et al. 2008).
result
Discussion
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The 21 RCTs [15-35] and 42 observational studies [36-77] (33 cohort, nine case-control) were included in the analysis.
background
Results
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The method takes advantage of the reaction of GSH with o-phthalaldehyde at pH 8.0 and of GSSG with o-phthalaldehyde at pH 12.0; GSH can be complexed to N-ethylmaleimide to prevent interference of GSH with the measurement of GSSG (17).
method
METHODS
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We also reported that the corresponding lysine residue of T. thermophilus acyl-CoA synthetase was propionylated (Okanishi et al. 2014).
background
Discussion
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For example, analysis of data for 36, 424 older people in four developed countries found frailty index values to be closely comparable across countries, increasing with age at approximately 3% per year in community-dwellers and correlating highly with mortality [28].
method
Methods
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Evidence for this specific role of piRNAs comes from the studies in y [5-7], zebrafish [8,9] and mouse [10-13].
background
Background
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The use of trifluoroacetic anhydride as a promoter for esterification of a variety of O-acylated chitin derivatives is also noted [5,6].
background
1. Introduction
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Extracellular signal-regulated kinase 1 and 2 (ERK1/2), the c-Jun amino-terminal kinase (JNK 12/3), p38 kinase, and ERK5 are the four alternative MAPKs activated by distinct stimuli [1].
background
1 Introduction
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These results are contrary to the long-held belief that monarch butterflies were most vulnerable to distur- bance on the wintering grounds since they congregate in a small area at high densities (Brower et al. 2002, 2004).
result
Discussion
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None
Surprisingly, only quite recently a suitable security model for proxy signatures has been introduced [4], and adopted to multi-level and identity-based proxy signature schemes later on [16].
method
1 Introduction
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Competition of BaP and BeP with [3H]2,3,7,8tetrachlorodibenzo-p-dioxin ([3H]TCDD) for binding to a trout AHR2αwasmeasured by velocity sedimentation in sucrose gradients in a vertical tube rotor (Tsui and Okey, 1981) as described earlier (Billiard et al., 2002; Karchner et al., 1999).
method
Methods
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As in past research (McBride et al. 2003), responses for girls’ menarche were coded (1 = no; 4 = yes) to create a scale comparable to other items and a mean score across all five items was computed for both girls, α=0.
method
Methods
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…and new Frontiers in Cellular Neuroscience www.frontiersin.org December 2014 | Volume 8 | Article 433 | 5 ideas regarding cell degeneration in ALS including, intracellular calcium dysregulation, mitochondria, oxidative stress, and possibly excitotoxicity (Martin, 2010a,b; Reddy and Reddy, 2011).
background
DISCUSSION
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We report results compared to [23] and test-time dropout, as those were the best competitors from Section 4.
result
4.2. Predicting traffic flows
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