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We compare the proposed classification algorithm (denoted as “CoLiBRi” for “Concept Lattice-Based Rule-learner”) with Scikit-learn [12] implementations of CART [2], Random Forest [1] and kNN on several datasets from the UCI machine learning repository.1 1 http://repository.seasr.org/Datasets/UCI/csv/ We used ...
method
5 Experiments
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We therefore contrast our work with state-of-the-art MI optimization algorithms included in the previously mentioned General Algebraic Modeling System (GAMS) (Bussieck and Meeraus, 2004) commercial algorithm suite as well as the Mixed-Integer Evolution Strategy (MIES) (Li et al., 2013).
result
1 Introduction
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The general conclusions have been that a bead beating step is needed, and the FastDNA spin kit for soil has been recommended due to general high yield and purity [10,12].
background
Introduction
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1250a9f81adb7b5eb87a1564599165b546155fdb
This may be due to the role of lysosomes in parvovirus-induced cell death, since the NAD /NADH system is involved in electron transport and acidification in these organelles (9).
background
DISCUSSION
b3a8c71f1316dd174d49173591f332f1c810a66c
c88727a6a6a9096be58a9db9993633eab9415fde
The resected specimens were classified as either low-grade mucinous carcinoma peritonei or high-grade mucinous carcinoma peritonei on pathologic evaluation by experienced peritoneal malignancy pathologist.(8) Postoperative complications were classified according to the Clavien– Dindo classification.
method
METHODS
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On the one hand, our findings are consistent with results from experimental animal studies that described environmental effects of early life stress on inflammation levels (Cole et al., 2012, Delpech et al., 2016).
result
4. Discussion
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We measured the diameters of terminal portion of the ICA; C7 segment (origin from posterior communicating artery to the bifurcation of the ICA) [31] on source image of TOF MRA.
method
2.3. Imaging analysis
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1fd0c7668ce617d710d69644692aa3655b1661d1
Antibodies recognizing mammalian homologs of katanin also recognize large microtubule-dependent structures surrounding γ-tubulin foci at spindle poles in several cell types and, in addition, recognize a smaller microtubule-independent focus at the centrosome in some cell types (McNally and Thomas, 1998).
background
INTRODUCTION
efaa33b745b1420d6bf13873a4df09680c7984e0
eb08d5a6852228a7b45deb22f1bf4dde945020c6
Although Hh signaling by SMOH was reported to be required in a chronic myeloid leukemia-like disease (Dierks et al., 2008; Zhao et al., 2009), it was found to be dispensable for the development of acute leukemias induced by either the Received 3 November 2009; revised 20 April 2010; accepted 20 May 2010; published onli...
background
Introduction
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91828be2a1e5b407bfee3b3c6ed77a7a3d40a137
Reported t-statistics are based on robust standard errors estimated using the Huber (1967) – White (1980) procedure.
method
Panel C Abnormal Returns to Passing Majority Voting Standard Proposals – Control for Other Governance Proposals
258873a1605d396db6308f7f2822f1a317def2e8
f9cce2ca192180e1a404a7577752a9c8ea8259ed
…plasticity deficits in hMT mice HFS of glutamatergic afferents led to the induction of robust LTD in MSNs in both coronal and parasagittal slices from NT mice, similar in magnitude and duration to that reported previously in mouse brain slices (Goldberg et al., 2005; Bonsi et al., 2008) (Fig.
background
Results
9d1c38923868aad077de91a389a27f72d592d329
badee7f8b87dbf9d38775bebaad489d664fe0ef3
On the other hand, negative regulation of flavonoidspecific genes by R2R3-MYB or R3-MYB proteins have also been reported in some species (Aharoni et al. 2001; Paolocci et al. 2011; Dubos et al. 2008; Matsui et al. 2008).
background
Introduction
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34e5513017c555463409013e0f16af946348f7bf
, 2002) and whose uptake is involved in the long-lasting enhancement of synaptic transmission and may therefore affect synaptic plasticity (Sergeeva et al., 2003).
background
INTRODUCTION
44a60f92dff13eef9b2c693ceed2706ae0ac7bec
e797ca1fd6cdb35d3ab4f709c1f45e7140df87d2
In this paper, AAUC is computed over the first 15 recall points: AAUC = 1 15 · 15∑ i=1 Precision(i).
method
6 Experiments
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Relationship satisfaction was assessed using Funk and Rogge’s (2007) four-item measure of relationship satisfaction. These items measured satisfaction with the participant’s romantic partner (e.g., “How rewarding is your relationship with your partner?” and “I have a warm and comfortable relationship with my ...
method
Method
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b7e6a9c4cf6a01d5f3d23ba28d3b4bd548e96e1c
Rabbits were divided into three groups: group 1 (sham), animals were anesthetized for 40 min, but no other intervention was performed prior to blood-draw; group 2 (rIPC), remote ischemic preconditioning was induced through four cycles of 5 min of hindlimb ischemia (via a tourniquet), followed by 5 min of reperfusion as...
method
Methods
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d5e469114f1e34e0d4e5d30931111b926cacfa3c
…or undermine the autoimmunity hypothesis (Kierszenbaum 1986, 1999, 2003, 2005; Eisen and Kahn 1991; Avila 1992; Fernandez et al. 1992; Kalil and CunhaNeto 1996; Brener and Gazzinelli 1997; Andrade 1999; Soares et al. 2001; Leon and Engman 2001, 2002; Gironés and Fresno 2003; Gironés et al. 2005).
background
Introduction
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36ee78368dc76d03d84c5ed9d0fd99a604b79042
For the CIFAR-10 dataset, the DNN architecture adopted by Carlini and Wagner is not state-of-the-art. erefore, we do not adopt their DNN architecture for the CIFAR-10 dataset.
method
6.1 Experimental Setup
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identified in the literature for nano-foods from a survey with a convenience sample in Switzerland (Siegrist et al. 2007).
background
Introduction
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These include issues such as the internalisation and pricing of knowledge assets (Markusen, 1984; 2002), the advantages of horizontal (Horstmann and Markusen, 1992; Markusen and Venables, 2000) and vertical integration (Aghion and Tirole, 1997; Grossman and Hart, 1986), and the advantages of subcontracting and licensin...
background
2 The nature of the multinational enterprise
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1f17ef15bbe9466e6b6b147b044da5264fd2560e
Horizontal CSTN and transverse spinal cord slices (L4-L6) from 2 to 4 weeks old rats were prepared using methods similar those previously described [52].
method
Methods
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cf0f5480b5dba14af9c23ad22df13f6970dc65e7
To determine the significance of the change from baseline of each lipid species, subclass, and class during the postprandial period (for dairy or soy meals) we performed the nonparametric Friedman test on the plasma concentration values and corrected for multiple comparisons by using the Benjamini-Hochberg method (23).
method
Methods
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9512f52337338232e1ed692748d9f069398ca545
section 3, excels for different types of applications and network constraints as discussed in [3], [23], [21], [22].
background
4 Non-chartered Routing Protocols
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49408e2483e51eea8636dffe6203b16dd7dc0fbe
tumor progression in non-muscle-invasive bladder cancer (NMIBC) patients treated with intravesical Bacillus Calmette-Guérin (BCG) [10].
method
2.2. Discussion
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3a681477ad66a92fdd771f1849e7a5eec702908c
These different estimates were mostly smaller than those reported by Trail et al. (1991b) in a governmental ranch of N Dama cattle in Gabon (PCV heritabilities at 0.64).
result
Discussion and conclusions
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e8da441ce4bdf2d044a5899681e162cef49dde4a
Huett et al. (2005) compared nitrogen and phosphorus removal from plant nursery runoff in vegetated SSF CWs and unvegetated filters in Australia, and reported that removal efficiency for planted wetlands increased from 63.4 and 69.1% for TN and NO3–
background
Introduction
7b0ca6f15e76f285cc19efd2305cb1ec9e16a5b5
df90f3e882609d15c298251608a5b48b69efb3b8
, 2009), particularly at altitudes less than 2 km, but found the overprediction to correlate with HCHO concentrations, indicating missing reactive VOCs in the model (Mao et al., 2009).
background
1 Introduction
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18bc8b07747174cbac2230f69e4d66800c0424e3
A decrease in stocking rate would result in further improvements in ecological integrity (Jansen et al. 1999; Fondell and Ball 2004; Martin and Possingham 2005; Dennis et al. 2008; Powell 2008; Little et al. 2013).
background
Discussion
d388588cbc8aef4f1eba7b56f1571191370f6e75
7348e48de2ad238df345015c6b9c42830bee728b
, 2002), the relationship between upslope pore pressure dynamics and hillslope discharge (Uchida et al., 2004) or event water ratio (e.
background
024a8840cf61cbc995d72493a2158c67511c76db
c0886a32265119da99359de6fff821ef49a773d3
Comparisons in inclusion criteria, screening parameters, and results of LDCT screening for lung cancer are summarized in Table 3 (22-26).
background
DISCUSSION
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eac613b0f8c1d283081834eed883c9eedce498db
The changes in glucose uptake in muscle and adipose cells overexpressing PED are accompanied by inhibition of insulin-dependent translocation of GLUT4, the major insulin-responsive glucose transporter (1).
background
Transport in the L6 Skeletal Muscle Cells
5b5a2f37c6269a761524c58f841af3547563ca71
a0c1529ae833f257ce31f98d030a5a110c86cc1c
western blots were developed with Odyssey CLx Infrared Imaging Systems (LI-COR, USA) [42, 60, 61].
method
Yeast two-hybrid screening
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f865cad3b24ef621d27922e86f96837d6235ff8e
Animals, chemicals, and antibodies All animals and chemicals used were previously described in Omezzine et al. (2003) and Bozec et al.
background
Materials and methods
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f456ce411f0e83ad2e4c2cadb68918406b2bb355
The age of giant nupDNA fragment A was calculated by dividing the corrected K value of type 2 substitutions (see Results) by the absolute substitution rate of the synonymous sites in the nuclear genes of rice (Ramakrishna et al., 2002).
method
METHODS
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Sarriot et al. (2004a) recommend moving assessment of organizational viability beyond its financial dimension.
background
METHODS
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43216a526d27321f1eb34a8c1d7309e40f3bec93
Constant comparison is a data analysis strategy that involves moving back and forth between the data and the scene of study comparing incident to incident until categories emerge (Beck, 2004).
background
Data Collection and Analysis
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Renin inhibitors bind to the active site of renin and inhibit its binding to angiotensinogen, which is the rate‐determining step of the RAS cascade and, consequently, prevents the formation of Ang I and Ang II (36).
background
Discussion
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25c287c5180650bbc40c0d485f0aacce9f33516e
Regarding camera sensors, the work of Jung et al (2014) explores information from a depthcamera, while a monocular camera is employed in (Wu et al 2009; Costante et al 2013), and an omnidirectional one in (Ullah et al 2008; Yuan et al 2011).
method
1 Introduction
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This session also helps to decrease the number of trials in the formal TMS sessions since the critical SSD does not then have to be obtained during the TMS trials and there is then a better chance to observe the effects of TMS (see also Chambers et al., 2007).
background
Baseline parameters
7defa9a85a97751fbb94a982d0e3ddc0a0fa14f0
02a2201ea91687ee01a868451a79cddca194f9e9
Specifically, the autonomous vehicle segmentation dataset KITTI (Ros et al. 2015) is used, augmented with 49 additional train images by (Kundu et al.
method
5 Results and discussion
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005cb5959175e4501dd5ddc96a22780788a9b219
For the wild-type receptor, the P119L mutant, the F122G mutant, and the T197A mutant, stably transfected cell lines were selected and assessed, as previously described (3).
method
Methods
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f756821621011ae527d578399406bb1cc48b4068
Enzymatic activity of purified NS2B(H)-NS3pro was assayed against commercially available synthetic peptide substrates containing either three non-prime side residues, Boc-GRR-amc and Boc-LRR-amc; four residues, Ac-nKRR-amc, Ac-nKRR-amc; and five residues, Pyr-RTKR-amc, and a previously described internally quenched DEN...
method
Materials and Methods
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Differences between central (aortic) and brachial BP could be clinically important, as central BP is more closely correlated with target organ damage in hypertension [4]; is differentially influenced by antihypertensive therapy compared with brachial BP [5]; and may be a superior predictor of cardiovascular events than...
background
INTRODUCTION
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The results obtained in our study agree with previous clinical observations that have failed to detect a link between administration of exogenous glutamate and clinical neurological injury in association with cardiac surgery.(11,12) The results also argue against a role for exogenous glutamate in the evolution of subcl...
result
4. Discussion
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…and Kockelkorn, 2006a, Damala and Kockelkorn, 2006b, Damala, 2007a, Damala, 2007b, Oppermann and Sprecht, 1998, Santoro et al., 2007) and “nomadic devices” (Brelot et al., 2005, Damala et al., 2005, Hsi, 2004, Vlahakis et al., 2005) are other variations often enough used in the relevant literature.
background
2.3.1.2 Multimedia Guides
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…genetic variation, but the disease phenotype does not only result from functional alteration of the affected gene product, perturbations rather spread along the links of the underpinning cellular networks (Schadt 2009; Barabási et al 2011; Menche et al 2015; Piñero et al 2016; Caldera et al 2017).
background
Introduction
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3d188c6936ad6dd478e01f2dd34bb2167f43e7d7
[37] Scores were described continuously from 0 to 27 to measure depression severity and also classified dichotomously as major depression (score .
background
Methods
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bbf10259c77b8124715d50c73dac46756fed745f
Bork et al. (2010) reported that highly significant differences in methylation patterns were observed at specific CpG sites, such as those near homeobox genes between early and late cultures.
background
Copyright ⓒ 2012 by the Korean Society for Biochemistry and Molecular Biology
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instance, are also important barriers to this activity (Davison et al., 2008).
background
DISCUSSION
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9daeced0925b74cec0cb589d2682c6c9060e669b
For example, in Table 2 BCR dataset is cross validated with three feature sets obtained from Lancet, CCR and 70-gene signature.
method
4.1. Experimental Setup
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…to a single transcript (e.g., reads originating from constitutive exons) or even to unique genomic locations, transcript- and gene-expression levels can only be estimated with some degree of certainty, that is, with estimation error (Jiang and Wong, 2009; Turro et al., 2011; Trapnell et al., 2013).
background
Results
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7c77cd228aef0769225ede4056c91726153bf986
5 mm,[6,13] absence of communications of both SIEVs crossing the abdominal midline,[6,13] absence of direct communications by perforators between the SIEV and the deep inferior epigastric vein (DIEV),[6] number of perforators of the flap,[5] and subcutaneous tissue thickness.
background
INTRODUCTION
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bc09dfbd0300f89c727c3b5f494b326fc0bb9b15
We confirmed the data of others that proliferating basal cells appear in patches or clusters (Moulton et al., 1970; Graziadei and Monti Graziadei, 1979; Monti Graziadei and Graziadei, 1979; Suzuki and Takeda, 1993; Huard and Schwob, 1995).
result
DISCUSSION
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We do not conclude from our results that neither factor ever plays a role; after all, the possible effects of both had been demonstrated previously (Seeley, 1986; Seeley and Tovey, 1994).
result
Discussion
47f463a59a526edd2dd33c5b9f24465c7fdcef49
None
Moreover, the value of t1/2 after i.v. administration of MBF was similar (13.78 h) to a previous report (Yohannes et al., 2015).
result
DISCUSSION
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9b1a3e2f02c6d981bd66d359d4ecf6165998355c
After testis irradiation, hypomethylation of retrotransposed interspersed repeat elements (LINEs and SINEs) was found in the offspring (Filkowski et al., 2010) next to lower levels of the methylated CpG binding protein MeCP2 and the DNA homologous recombination Assisted reproduction and epigenetic…
method
Methods
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639168baf699b6e3b61860ab007d1a2e2d36a931
heterozygote advantage due to heterotic selection (Clegg, 1980; Rüter et al., 2000).
background
Results
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6f7538c7e2d0f2c447e54f180f9946dea18f77e1
modeled in terms of CA, including the Belousov–Zhabotinsky (BZ) reaction [1,2], the Turing system [3], a precipitating BZ system for computation of Voronoi diagram [4,5], and
method
1. Introduction
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46ab96642801198bbd20f1136fbcc1984a828033
A retrospective cohort study abstracted medical records of 45,308 Medicare beneficiaries with AMI.(87) Of these, 7.
background
Percutaneous Transluminal Coronary Angioplasty (PTCA)
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2f0f0aacbdba5a5f539e2182cb828f46d27750c0
GC content for each gene was obtained from the Conditional Quantile Normalization R package for 15 277 genes (17).
method
Methods
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It has been previously reported that the blockage of the replication machinery can lead to uncoupling of leading and lagging strand synthesis, resulting in the generation of ssDNA, which in turn will be occupied by RPA, an SSB (38, 39).
background
Results
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d1a5938000f9abacebfc1285387aa0355c26ef81
The methodology is primarily influenced by the Grounded Theory approach, which has been used successfully in previous studies (Jones, 2004; Orlikowski & Iacono, 2001).
method
4 METHODOLOGY
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9930abd541f7c943aaf32cf496ca2fc74fca0309
Deficits were more pronounced in the right than in the left hemisphere (Ballmaier et al, 2004c), implying a possible involvement of abnormalities in inter-hemispheric information transfer in late-onset depression (Kumar et al, 2000).
background
DISCUSSION
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b0c33fc55f6e792b359b025a8b811fb420d77d3a
Based on the new results and previous findings (12, 21, 22), we propose a functional model for CmeR in which it binds to target DNA via its N-terminal HTH motif and interacts with various inducing signals via its large ligand-binding pocket located in the Cterminal region.
result
DISCUSSION
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c4824a86d09c8efae6ab1a25e5ced8a5ec4990b6
In trials with zebra ®nches, the numbers of sperm collected using false cloacas (Pellatt and Birkhead 1994) are similar to those produced by natural copulations determined by comparing the number of sperm in the seminal glomera of males that had or had not recently copulated (Birkhead et al. 1993).
method
Methods
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These studies showed that expression of miR-99a could reduce the expression of a number of proto-oncogenes by targeting their 3′ untranslated region (3′UTR) [8-13].
background
Introduction
4d9170a8daa2f40530580a24e8490f569eaf15d7
d6eaf36357406cc26c09d36fc88d8974ba49807d
Bacterial strains, plasmids, and media Escherichia coli JM109 (Yanisch-Perron et al. 1985) and pGEM-T Easy (Promega, Madison, USA) were used in routine gene manipulation.
method
Methods
ae5c30a06f5ca031995b1f927837a129a8c4485b
78911275d860765228a15e8df0a3503df268257e
…proteins initially has been demonstrated in tissue culture model systems of adipogenesis and hematopoiesis (Lin and Lane 1992; Freytag et al. 1994; Hu et al. 1995; Müller et al. 1995; Nerlov et al. 1998) and has now been firmly established through analysis of the respective knockout mice…
background
1991; Samuelsson et al. 1991; Lin and Lane 1992; Scott et al. 1992; Chandrasekaran and Gordon 1993; Piontkewitz
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The 2 cycles/letter formula [16,17] suggests that the most important spatial frequency content of these letters is :2.
background
2. Methods
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565b93f391229bf12558555473d29fe7fab56ac4
At present, pulmonary fibrosis model can be constructed by several methods, including paraquat and amiodarone [21, 22].
background
4. Discussion
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19203ba6a8611651b6e822ec41f525405235f65c
org variability in parasites (Pieniazek et al. 1999; Chicharro, Jimenez and Alvar, 2003; Pratlong et al. 2003).
background
5da3d654c890385d284d0845286bd9d26e77d036
ebbac2abac129b92d95e3f03499ba36bfa8bcf32
brood size), while males tend to increase their amount of care with increasing work load (Santos and Nakagawa 2012).
background
Discussion
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f30312caf49194b294b589b3b9f71d95136acc45
How ever, in recent years, X linked genes have been shown to be expressed in both parental chromosomes in the human placenta (Moreira de Mello et al., 2010).
background
RESULTS AND DISCUSSION
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15eec589ff38fe1c516fec25648a77ab90c8e832
Therefore, the risk of selection bias and confounding is greater than in a review of RCTs [58].
background
Strength and limitations
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The large majority of T6SS genes (12 out of 17), including VipA, VipB, ClpV, VasF and VasK, are required for Hcp secretion, killing of amoeba and bacteria and are predicted to encode structural T6SS components [9,12,20].
background
Discussion
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However, the clinical value of CA125 as a marker of ovarian cancer is low, due to its expression in non-malignant or non-ovarian malignant conditions (Tuxen et al, 1995; Meyer and Rustin, 2000).
background
DISCUSSION
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The quality of physician–patient communication has been associated with patient adherence to treatment (Zolnierek & Dimatteo, 2009), uptake of cancer screening (Carcaise-Edinboro & Bradley, 2008), improved blood pressure control in hypertensive patients (Orth, Stiles, Scherwitz, Hennrikus, & Vallbona, 1987), and reduct...
background
Introduction
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ly), which have been originally identified as molecules activated by growth factor-stimulation of fibroblusts, are key kinases in the intracellular signal transduction pathways (1-6).
background
INTRODUCTION
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Bacterial strains and growth conditions Listeria monocytogenes EGDe was used for all experiments except for the D-alanine auxotrophy experiments, which were performed with L.monocytogenes strain DP-L3506 [23].
method
Methods
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These finding are consistent with the findings of other studies of Hispanic mothers [12,13,23] and parents [26].
result
Discussion
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None
Partial or complete deletion of CS2, as in the case of ABF1 (1-643) and (1-638), doubled the plasmid loss rate of pARS1 (compare column 1 with columns 5 and 7 in Fig.
background
RESULTS
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The hypothesis that GBI scores differ from 0 (with 0 meaning no effect of the operation on HRQOL) was tested by the t test for independent samples (> = 0.05).
method
METHODS
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…proteins like PLA2, three-finger toxins, etc. have evolved via mutations targeted around their functional domains while the structural residues are constrained and maintain a highly conserved scaffold (Mackessy 2002; Kini 2004; Fry et al. 2006, 2008; Yamazaki and Morita 2007; Doley et al. 2008).
background
Results and Discussion
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The upregulated PDHC expression level upon ND was in line with the previous findings that upregulation of PDHCmediated acetylCoA synthesis contributed to the augmented TAG accumulation (Li et al. 2014b; Jia et al. 2015).
result
Discussion
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…into 34 different gyral regions per hemisphere, for each of which a mean cortical thickness value was calculated (Desikan et al. 2006; Fischl et al. 2004b) Automated Freesurfer subcortical parcellation was employed to extract volumes for the amygdala, hippocampus, whole brain grey…
method
Methods
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[14] collected misinformation automatically in order to prevent false information from spreading through social media.
background
2 Related Work
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In one recent study using the tractography applying constrained spherical deconvolution to investigate a total of 43 patients with ADHD, Silk et al. (2016) found a significant lateralization to the left for fractional anisotropy (FA, a DTI measurement) in the putamen tracts.
background
Introduction
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loss was tested in the context of overexpression of the oncogene NRAS and a short hairpin against p53, because ATRX mutation by itself is not associated with cancer development in humans (12), and glial tumors with ATRX mutations almost always include TP53 mutations (1).
method
RESULTS
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, 2012), and other studies have indicated that the fornix is affected in Pick’s disease, FTD with tau mutation, or TAR-DNA-binding protein43 type C pathology, but not for FTD caused by a progranulin mutation or with fused-in-sarcoma protein accumulation (Rohrer et al., 2011; Hornberger et al., 2012).
result
DIAGNOSIS AND PREDICTION
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Therefore, the relay layout is of great importance in the cooperative wireless-powered systems [16, 25].
background
C. Key Parameters
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Furthermore, the quality of RNA may vary significantly with each extraction and during experimentation resulting in a constant requirement for monitoring of RNA quality (Schroeder et al. 2006).
background
Introduction
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Other studies suggest that altering affinity to FcRn might alter the bioavailability of mAbs (Deng et al., 2010; Deng et al., 2012), and SC bioavailability appears lower in FcRn-deficient mice as compared to wild type animals (Wang et al.
background
DISCUSSION
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Also, HA can interact with various cellular receptors, including CD44, RHAMM, and LYVE-1, to promote angiogenesis [6], as well as the growth, invasion and metastasis of tumors [7-9].
background
Introduction
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Electrophoretic mobility shift assays (EMSAs) were performed as previously described (8, 10, 22, 39).
method
METHODS
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The use of GDNF and GFRa1 to trigger RET downstream pathways is in accordance with other previously published reports [36,48] and also relies on the fact that GDNF is the strongest activator of RET signaling in enteric glial cells upon a number of physiological and pathological events[55].
result
Discussion
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These observations are in agreement with the studies of pcy mice model by Okada et al, showing that both cystic epithelial cells and interstitial fibroblasts express higher levels of collagens compared to normal controls [10].
result
Discussion
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This finding is similar to those reported in colonization screening by other authors [20].
result
Discussion
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Sensitivity analysis revealed that 11 independent studies were the main source of heterogeneity[21,26–29,31–36].
background
Results
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FGF23 Activates FGFR4 and PLCg Signaling in the Absence of a-Klotho To study FGF-FGFR-dependent signaling, we used HEK293 cells that express all FGFR isoforms but lack a-klotho (data not shown), similar to cardiac myocytes (Faul et al., 2011).
method
RESULTS
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Despite the lower number of patches utilized, this study will use slightly larger sample sizes of dispersed seedlings than Grivet et al. (2009), incorporating subsequent improvements in genotypic assignment (Smouse et al. 2012).
method
Sampling design
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