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PMC1065321_F5_1629.jpg | Describe the main subject of this image. | Establishment of the KRN serum transfer model. (a) Discoloration and swelling (arrow) of the right third proximal interphalangeal joint is noted in a healthy C57BL/6 mouse 4 days after KRN serum transfer. (b) Near-infrared fluorescent imaging of the right paw showed increase fluorescence signal intensity at the inflamm... |
PMC1065321_F5_1630.jpg | What is being portrayed in this visual content? | Establishment of the KRN serum transfer model. (a) Discoloration and swelling (arrow) of the right third proximal interphalangeal joint is noted in a healthy C57BL/6 mouse 4 days after KRN serum transfer. (b) Near-infrared fluorescent imaging of the right paw showed increase fluorescence signal intensity at the inflamm... |
PMC1065321_F6_1633.jpg | What's the most prominent thing you notice in this picture? | Early detection (30 hours after KRN serum transfer) of the inflammatory joint by NIR2-folate. (a) White-light image showed no remarkable swelling at bilateral paws. (b) Merged near-infrared fluorescent signal with a white-light image showed increase fluorescence signal intensity at the dorsal aspect of the right wrist,... |
PMC1065321_F6_1634.jpg | What is the main focus of this visual representation? | Early detection (30 hours after KRN serum transfer) of the inflammatory joint by NIR2-folate. (a) White-light image showed no remarkable swelling at bilateral paws. (b) Merged near-infrared fluorescent signal with a white-light image showed increase fluorescence signal intensity at the dorsal aspect of the right wrist,... |
PMC1065323_F2_1648.jpg | What is the dominant medical problem in this image? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1647.jpg | What object or scene is depicted here? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1645.jpg | What does this image primarily show? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1649.jpg | Describe the main subject of this image. | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1644.jpg | What is shown in this image? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1650.jpg | What can you see in this picture? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1653.jpg | What stands out most in this visual? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1651.jpg | What's the most prominent thing you notice in this picture? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1643.jpg | What is the core subject represented in this visual? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065323_F2_1646.jpg | What is being portrayed in this visual content? | Expression of CD4, CD20, CD45RO, CCR7, CCR5 and CXCR3 in synovial tissue obtained from patients with juvenile idiopathic arthritis (JIA) after synoviectomy. (a, b) Presence of CCR7+ cells (red) in the sublining layer of a synovial tissue characterised by a diffuse lymphocytic infiltrate (scattered CD4+ cells, brown) fr... |
PMC1065329_F2_1655.jpg | What is shown in this image? | Normal human knee articular cartilage. The optical coherence tomography (OCT) image (a) of the cartilage is relatively thick and uniform. The pronounced banding pattern on the OCT image is due to the birefringence of the highly organized structure of the collagen (red arrows). The alternating maximum and minimum intens... |
PMC1065329_F2_1654.jpg | What is the focal point of this photograph? | Normal human knee articular cartilage. The optical coherence tomography (OCT) image (a) of the cartilage is relatively thick and uniform. The pronounced banding pattern on the OCT image is due to the birefringence of the highly organized structure of the collagen (red arrows). The alternating maximum and minimum intens... |
PMC1065329_F6_1657.jpg | What stands out most in this visual? | Optical coherence tomography image of cartilage from femur and patella consisting of adjacent areas of normal and diseased tissue. The banding pattern is attenuated and lost in diseased areas (on the right portion of each image). In addition, back-scattering intensity is abruptly reduced. |
PMC1065704_pbio-0030050-g002_1660.jpg | What object or scene is depicted here? | Magnetic Resonance Imaging of BrainsThree-dimensional reconstruction of a reference bonobo (pygmy chimpanzee) brain (A) and a reference human brain (B) after magnetic resonance imaging and normalisation of absolute brain sizes. The virtual bonobo brain has been transformed into the virtual human brain using an elastic ... |
PMC1065704_pbio-0030050-g002_1658.jpg | What is shown in this image? | Magnetic Resonance Imaging of BrainsThree-dimensional reconstruction of a reference bonobo (pygmy chimpanzee) brain (A) and a reference human brain (B) after magnetic resonance imaging and normalisation of absolute brain sizes. The virtual bonobo brain has been transformed into the virtual human brain using an elastic ... |
PMC1069664_pmed-0020068-g001_1662.jpg | What stands out most in this visual? | Specialized Myofibers in a Mammalian Skeletal MuscleA cross-section of the gastrocnemius muscle of a mouse has been stained to detect myoglobin, which is found selectively in slow oxidative and fast oxidative myofibers (stained brown), but not in fast glycolytic myofibers (unstained). Human muscles exhibit a similar mo... |
PMC1074344_F2_1664.jpg | What is the focal point of this photograph? | An example of histological sections of tongue stained with chloroacetate esterase for identification of mast cells in littermate controls (A) and Wf/Wf (B) mice. Note mast cells appear as brilliant red colour. Scale bar = 100µm. |
PMC1074344_F2_1663.jpg | What does this image primarily show? | An example of histological sections of tongue stained with chloroacetate esterase for identification of mast cells in littermate controls (A) and Wf/Wf (B) mice. Note mast cells appear as brilliant red colour. Scale bar = 100µm. |
PMC1074811_pbio-0030127-g003_1665.jpg | What's the most prominent thing you notice in this picture? | Antarctic Circumpolar WaveIn 1996, oceanographers Warren White and Ray Peterson identified significant inter-annual variations in the atmospheric pressure at sea level, wind stress, sea surface temperature, and sea-ice extent over the Southern Ocean. They called this system of coupled anomalies the Antarctic Circumpola... |
PMC1074815_pbio-0030137-g003_1667.jpg | What is the dominant medical problem in this image? | Neuronal Odor Coding and Odor Space in Bees(A) Schematic view of odor processing in the honeybee brain. Some 60,000 odorant receptor cells are distributed along the antenna. These belong to several different types (illustrated with different colors), each responsive to a different set of chemicals. Axons from like rece... |
PMC1079804_F4_1678.jpg | What is shown in this image? | Morpholino antisense knockdown of zNXT2 in transgenic zebrafish embryos expressing cmlc2-GFP and flk-RFP. zNXT2 knockdown causes pericardial edema (compare A, C, E, G with B, D, F, H), abnormal relative positions of two chambers and chamber dilation (compare insets in C-H showing CMLC2 promoter driven GFP expression pa... |
PMC1079804_F4_1672.jpg | What is the focal point of this photograph? | Morpholino antisense knockdown of zNXT2 in transgenic zebrafish embryos expressing cmlc2-GFP and flk-RFP. zNXT2 knockdown causes pericardial edema (compare A, C, E, G with B, D, F, H), abnormal relative positions of two chambers and chamber dilation (compare insets in C-H showing CMLC2 promoter driven GFP expression pa... |
PMC1079804_F4_1673.jpg | What is the dominant medical problem in this image? | Morpholino antisense knockdown of zNXT2 in transgenic zebrafish embryos expressing cmlc2-GFP and flk-RFP. zNXT2 knockdown causes pericardial edema (compare A, C, E, G with B, D, F, H), abnormal relative positions of two chambers and chamber dilation (compare insets in C-H showing CMLC2 promoter driven GFP expression pa... |
PMC1079804_F4_1677.jpg | What's the most prominent thing you notice in this picture? | Morpholino antisense knockdown of zNXT2 in transgenic zebrafish embryos expressing cmlc2-GFP and flk-RFP. zNXT2 knockdown causes pericardial edema (compare A, C, E, G with B, D, F, H), abnormal relative positions of two chambers and chamber dilation (compare insets in C-H showing CMLC2 promoter driven GFP expression pa... |
PMC1079804_F4_1674.jpg | What's the most prominent thing you notice in this picture? | Morpholino antisense knockdown of zNXT2 in transgenic zebrafish embryos expressing cmlc2-GFP and flk-RFP. zNXT2 knockdown causes pericardial edema (compare A, C, E, G with B, D, F, H), abnormal relative positions of two chambers and chamber dilation (compare insets in C-H showing CMLC2 promoter driven GFP expression pa... |
PMC1079804_F4_1669.jpg | What is the principal component of this image? | Morpholino antisense knockdown of zNXT2 in transgenic zebrafish embryos expressing cmlc2-GFP and flk-RFP. zNXT2 knockdown causes pericardial edema (compare A, C, E, G with B, D, F, H), abnormal relative positions of two chambers and chamber dilation (compare insets in C-H showing CMLC2 promoter driven GFP expression pa... |
PMC1079822_F2_1682.jpg | What is being portrayed in this visual content? | Isolation of unc-4::GFP neurons by FACS. A. Fluorescence intensity profile of wildtype (non-GFP) cells. Boxed areas exclude autofluorescent7 cells (arrow). B. unc-4::GFP cells are gated to exclude propidium iodide-stained (non-viable) cells. C. Light scattering gate for GFP-positive cells (circle) to exclude cell clump... |
PMC1079822_F2_1684.jpg | What's the most prominent thing you notice in this picture? | Isolation of unc-4::GFP neurons by FACS. A. Fluorescence intensity profile of wildtype (non-GFP) cells. Boxed areas exclude autofluorescent7 cells (arrow). B. unc-4::GFP cells are gated to exclude propidium iodide-stained (non-viable) cells. C. Light scattering gate for GFP-positive cells (circle) to exclude cell clump... |
PMC1079822_F2_1685.jpg | What is the principal component of this image? | Isolation of unc-4::GFP neurons by FACS. A. Fluorescence intensity profile of wildtype (non-GFP) cells. Boxed areas exclude autofluorescent7 cells (arrow). B. unc-4::GFP cells are gated to exclude propidium iodide-stained (non-viable) cells. C. Light scattering gate for GFP-positive cells (circle) to exclude cell clump... |
PMC1079822_F2_1686.jpg | What is shown in this image? | Isolation of unc-4::GFP neurons by FACS. A. Fluorescence intensity profile of wildtype (non-GFP) cells. Boxed areas exclude autofluorescent7 cells (arrow). B. unc-4::GFP cells are gated to exclude propidium iodide-stained (non-viable) cells. C. Light scattering gate for GFP-positive cells (circle) to exclude cell clump... |
PMC1079822_F2_1687.jpg | What is the main focus of this visual representation? | Isolation of unc-4::GFP neurons by FACS. A. Fluorescence intensity profile of wildtype (non-GFP) cells. Boxed areas exclude autofluorescent7 cells (arrow). B. unc-4::GFP cells are gated to exclude propidium iodide-stained (non-viable) cells. C. Light scattering gate for GFP-positive cells (circle) to exclude cell clump... |
PMC1079854_F4_1690.jpg | What's the most prominent thing you notice in this picture? | Optical sections of a pair of D. grandis cells. The series is in order from left to right of the images within a row and from top to bottom of the rows within the figure. Images are taken at 100 nm intervals. |
PMC1079854_F4_1689.jpg | What object or scene is depicted here? | Optical sections of a pair of D. grandis cells. The series is in order from left to right of the images within a row and from top to bottom of the rows within the figure. Images are taken at 100 nm intervals. |
PMC1079854_F5_1691.jpg | What is the dominant medical problem in this image? | Optical sections of a pair of D. murrayi tetrads. The series is in order from left to right of the images within a row and from top to bottom of the rows within the figure. Images are taken at 100 nm intervals. |
PMC1079854_F6_1692.jpg | What does this image primarily show? | Optical sections of a pair of D. radiopugnans cells. The series is in order from left to right of the images within a row and from top to bottom of the rows within the figure. Images are taken at 100 nm intervals. |
PMC1079854_F6_1693.jpg | What is the central feature of this picture? | Optical sections of a pair of D. radiopugnans cells. The series is in order from left to right of the images within a row and from top to bottom of the rows within the figure. Images are taken at 100 nm intervals. |
PMC1079854_F9_1694.jpg | Can you identify the primary element in this image? | An epifluorescence image of Thermus aquaticus. |
PMC1079854_F10_1695.jpg | What is shown in this image? | Optical sections of a Rubrobacter radiotolerans cell. The series is in order from left to right of the images within a row and from top to bottom of the rows within the figure. Images are taken at 100 nm intervals. |
PMC1079861_F1_1696.jpg | What's the most prominent thing you notice in this picture? | Preoperative anteroposterior radiograph of the elbow revealing fracture lateral condyle in association with posterolateral dislocation of elbow. |
PMC1079861_F2_1697.jpg | What's the most prominent thing you notice in this picture? | Preoperative lateral radiograph of the elbow revealing elbow dislocation. |
PMC1079865_F2_1698.jpg | What object or scene is depicted here? | Orbital anatomy. High-resolution axial T1-weighted native MRI of a volunteer without structural abnormalities at 3.0 Tesla. Structures removed during enucleation (globe, part of the optic nerve, insertions of the external eye muscles) are highlighted by the red ellipse. |
PMC1079867_F3_1700.jpg | What is the focal point of this photograph? | Electron microscopic appearance of the spinal motor neuron cytoskeleton. Embedment-free electron micrographs of two motor neurons within frog lumbar spinal cord extracted as described in Methods. The extracted spinal cord, from which the motor neurons were not isolated, was fixed with 2.5% glutaraldehyde and embedded a... |
PMC1079868_F7_1703.jpg | What's the most prominent thing you notice in this picture? | Hyperosmotic stimulus increases VEGF expression within SON neurons. A-B: Immunostaining for VEGF in control (A) and 6 days osmotically stimulated adult rats (B). Stack confocal images (10 μm-thick) of SON neurons show that moderate VEGF immunostaining is localized to perinuclear, golgi-like structures in the control ra... |
PMC1079868_F7_1702.jpg | What is being portrayed in this visual content? | Hyperosmotic stimulus increases VEGF expression within SON neurons. A-B: Immunostaining for VEGF in control (A) and 6 days osmotically stimulated adult rats (B). Stack confocal images (10 μm-thick) of SON neurons show that moderate VEGF immunostaining is localized to perinuclear, golgi-like structures in the control ra... |
PMC1079868_F7_1704.jpg | What is the focal point of this photograph? | Hyperosmotic stimulus increases VEGF expression within SON neurons. A-B: Immunostaining for VEGF in control (A) and 6 days osmotically stimulated adult rats (B). Stack confocal images (10 μm-thick) of SON neurons show that moderate VEGF immunostaining is localized to perinuclear, golgi-like structures in the control ra... |
PMC1079882_F2_1707.jpg | Can you identify the primary element in this image? | The effect of araC on the morphology of 4D/WT and D/v-src cells treated with or without 3 μM AA or DHA. 4D/WT cells (A, B, C) or D/v-src cells (D, E, F) were cultured in medium supplemented with 3 μM AA (B, E) or DHA (C, F) or a medium without the fatty acid supplementation (A, D) for 24 h. Cells were then treated with... |
PMC1079882_F2_1711.jpg | What is the focal point of this photograph? | The effect of araC on the morphology of 4D/WT and D/v-src cells treated with or without 3 μM AA or DHA. 4D/WT cells (A, B, C) or D/v-src cells (D, E, F) were cultured in medium supplemented with 3 μM AA (B, E) or DHA (C, F) or a medium without the fatty acid supplementation (A, D) for 24 h. Cells were then treated with... |
PMC1079882_F2_1708.jpg | What is being portrayed in this visual content? | The effect of araC on the morphology of 4D/WT and D/v-src cells treated with or without 3 μM AA or DHA. 4D/WT cells (A, B, C) or D/v-src cells (D, E, F) were cultured in medium supplemented with 3 μM AA (B, E) or DHA (C, F) or a medium without the fatty acid supplementation (A, D) for 24 h. Cells were then treated with... |
PMC1079882_F2_1710.jpg | Describe the main subject of this image. | The effect of araC on the morphology of 4D/WT and D/v-src cells treated with or without 3 μM AA or DHA. 4D/WT cells (A, B, C) or D/v-src cells (D, E, F) were cultured in medium supplemented with 3 μM AA (B, E) or DHA (C, F) or a medium without the fatty acid supplementation (A, D) for 24 h. Cells were then treated with... |
PMC1079893_F1_1717.jpg | What is the principal component of this image? | Damage produced by each model of bladder damage and binding of Texas Red-labelled chondroitin sulphate to mouse bladder. Images in the first two columns are transmitted light images of bladder sections stained with H&E or Acid Alcian Blue to demonstrate bladder damage. Acid Alcian Blue binds to glycosaminoglycans and t... |
PMC1079893_F1_1721.jpg | What is the dominant medical problem in this image? | Damage produced by each model of bladder damage and binding of Texas Red-labelled chondroitin sulphate to mouse bladder. Images in the first two columns are transmitted light images of bladder sections stained with H&E or Acid Alcian Blue to demonstrate bladder damage. Acid Alcian Blue binds to glycosaminoglycans and t... |
PMC1079893_F1_1716.jpg | What can you see in this picture? | Damage produced by each model of bladder damage and binding of Texas Red-labelled chondroitin sulphate to mouse bladder. Images in the first two columns are transmitted light images of bladder sections stained with H&E or Acid Alcian Blue to demonstrate bladder damage. Acid Alcian Blue binds to glycosaminoglycans and t... |
PMC1079893_F1_1715.jpg | Can you identify the primary element in this image? | Damage produced by each model of bladder damage and binding of Texas Red-labelled chondroitin sulphate to mouse bladder. Images in the first two columns are transmitted light images of bladder sections stained with H&E or Acid Alcian Blue to demonstrate bladder damage. Acid Alcian Blue binds to glycosaminoglycans and t... |
PMC1079893_F1_1713.jpg | What is the core subject represented in this visual? | Damage produced by each model of bladder damage and binding of Texas Red-labelled chondroitin sulphate to mouse bladder. Images in the first two columns are transmitted light images of bladder sections stained with H&E or Acid Alcian Blue to demonstrate bladder damage. Acid Alcian Blue binds to glycosaminoglycans and t... |
PMC1079893_F1_1714.jpg | What is the principal component of this image? | Damage produced by each model of bladder damage and binding of Texas Red-labelled chondroitin sulphate to mouse bladder. Images in the first two columns are transmitted light images of bladder sections stained with H&E or Acid Alcian Blue to demonstrate bladder damage. Acid Alcian Blue binds to glycosaminoglycans and t... |
PMC1079893_F1_1719.jpg | What can you see in this picture? | Damage produced by each model of bladder damage and binding of Texas Red-labelled chondroitin sulphate to mouse bladder. Images in the first two columns are transmitted light images of bladder sections stained with H&E or Acid Alcian Blue to demonstrate bladder damage. Acid Alcian Blue binds to glycosaminoglycans and t... |
PMC1079899_F3_1727.jpg | What does this image primarily show? | MR data with aligned sonographical data. Shown are the corresponding MR data set of the pelvic floor to the US data set from Fig. 2. (a) shows the axial plane from the axial data set; (b) and (c) show the sagittal respectively coronal plane from the corresponding sagittal data set. (c) is shown only for illustration pu... |
PMC1079899_F3_1722.jpg | What can you see in this picture? | MR data with aligned sonographical data. Shown are the corresponding MR data set of the pelvic floor to the US data set from Fig. 2. (a) shows the axial plane from the axial data set; (b) and (c) show the sagittal respectively coronal plane from the corresponding sagittal data set. (c) is shown only for illustration pu... |
PMC1079899_F3_1723.jpg | What is the core subject represented in this visual? | MR data with aligned sonographical data. Shown are the corresponding MR data set of the pelvic floor to the US data set from Fig. 2. (a) shows the axial plane from the axial data set; (b) and (c) show the sagittal respectively coronal plane from the corresponding sagittal data set. (c) is shown only for illustration pu... |
PMC1079899_F2_1730.jpg | What key item or scene is captured in this photo? | Sonographical data. Sonographical documentation method for examination of the pelvic floor in analogon to the usual used MR nomenclature [36, 37]. Shown is the filtered US data set: (a) axial, (left side: not filtered to show the enhancement induced by filtering) (b) sagittal and (c) coronal plane through the anal cana... |
PMC1079899_F2_1731.jpg | What's the most prominent thing you notice in this picture? | Sonographical data. Sonographical documentation method for examination of the pelvic floor in analogon to the usual used MR nomenclature [36, 37]. Shown is the filtered US data set: (a) axial, (left side: not filtered to show the enhancement induced by filtering) (b) sagittal and (c) coronal plane through the anal cana... |
PMC1079899_F2_1729.jpg | Describe the main subject of this image. | Sonographical data. Sonographical documentation method for examination of the pelvic floor in analogon to the usual used MR nomenclature [36, 37]. Shown is the filtered US data set: (a) axial, (left side: not filtered to show the enhancement induced by filtering) (b) sagittal and (c) coronal plane through the anal cana... |
PMC1079899_F2_1728.jpg | What is the principal component of this image? | Sonographical data. Sonographical documentation method for examination of the pelvic floor in analogon to the usual used MR nomenclature [36, 37]. Shown is the filtered US data set: (a) axial, (left side: not filtered to show the enhancement induced by filtering) (b) sagittal and (c) coronal plane through the anal cana... |
PMC1079905_F7_1732.jpg | What is the dominant medical problem in this image? | Histologic changes in a patient with CPLX and ESRD. Breast biopsy (benign) from a non-diabetic 60-year-old Caucasian female with an irregular breast mass 12 months prior to the development of clinical abdominal CPLX (multiple tumorous calcifications in the abdominal adipose tissue and skin ulceration). These tissue sec... |
PMC1079905_F7_1734.jpg | What is the focal point of this photograph? | Histologic changes in a patient with CPLX and ESRD. Breast biopsy (benign) from a non-diabetic 60-year-old Caucasian female with an irregular breast mass 12 months prior to the development of clinical abdominal CPLX (multiple tumorous calcifications in the abdominal adipose tissue and skin ulceration). These tissue sec... |
PMC1079905_F7_1735.jpg | What is the main focus of this visual representation? | Histologic changes in a patient with CPLX and ESRD. Breast biopsy (benign) from a non-diabetic 60-year-old Caucasian female with an irregular breast mass 12 months prior to the development of clinical abdominal CPLX (multiple tumorous calcifications in the abdominal adipose tissue and skin ulceration). These tissue sec... |
PMC1079905_F10_1736.jpg | Can you identify the primary element in this image? | Neuronal calciphylaxis. This image demonstrates not only medial calcification of an arteriole but also calcification of the epineurium of a peripheral neuronal unit within the subcutaneous tissue of a patient with systemic CPLX. This is from the same patient and breast biopsy tissue as in figure 7. Calcium stains black... |
PMC1079913_F1_1737.jpg | Describe the main subject of this image. | 1A: Longitudinal scan of the patient's right iliac crest. The b-mode image shows a small subcutaneous onchocercoma. Measurement is shown in the largest transverse and longitudinal section of the nodule. In this homogenous onchocercoma no worm movements were detected. 1B: Longitudinal scan of the crena analis. A medium ... |
PMC1079913_F5_1739.jpg | What does this image primarily show? | 5A: Live adult female of O. volvulus of a placebo treated patient. A nucleus (nc) in the hypodermis of the body wall (lateral cord) is visible as sign of vitality of the worm. The intestine appears darker beside the two sections of the uterus. (Magnification × 40) 5B: Section of the same onchocercoma as seen in 5A. The... |
PMC1079913_F5_1740.jpg | What does this image primarily show? | 5A: Live adult female of O. volvulus of a placebo treated patient. A nucleus (nc) in the hypodermis of the body wall (lateral cord) is visible as sign of vitality of the worm. The intestine appears darker beside the two sections of the uterus. (Magnification × 40) 5B: Section of the same onchocercoma as seen in 5A. The... |
PMC1079925_F2_1742.jpg | What is the core subject represented in this visual? | A pre-surgical CT scan of the chest showing the tumour. |
PMC1079928_F2_1744.jpg | What is the core subject represented in this visual? | Localisation of E-cadherin and integrin subunit αv. A-D: E-cadherin; E-H: integrin subunit αv, both detected by confocal laser scanning microscopy. Note that both adhesion molecules are located in all plasma membrane domains, including the apical one. Typical patterns are presented for apical (apical) and basal (basal)... |
PMC1079928_F2_1743.jpg | What does this image primarily show? | Localisation of E-cadherin and integrin subunit αv. A-D: E-cadherin; E-H: integrin subunit αv, both detected by confocal laser scanning microscopy. Note that both adhesion molecules are located in all plasma membrane domains, including the apical one. Typical patterns are presented for apical (apical) and basal (basal)... |
PMC1079928_F2_1746.jpg | What key item or scene is captured in this photo? | Localisation of E-cadherin and integrin subunit αv. A-D: E-cadherin; E-H: integrin subunit αv, both detected by confocal laser scanning microscopy. Note that both adhesion molecules are located in all plasma membrane domains, including the apical one. Typical patterns are presented for apical (apical) and basal (basal)... |
PMC1079928_F2_1749.jpg | What is shown in this image? | Localisation of E-cadherin and integrin subunit αv. A-D: E-cadherin; E-H: integrin subunit αv, both detected by confocal laser scanning microscopy. Note that both adhesion molecules are located in all plasma membrane domains, including the apical one. Typical patterns are presented for apical (apical) and basal (basal)... |
PMC1079928_F2_1747.jpg | Describe the main subject of this image. | Localisation of E-cadherin and integrin subunit αv. A-D: E-cadherin; E-H: integrin subunit αv, both detected by confocal laser scanning microscopy. Note that both adhesion molecules are located in all plasma membrane domains, including the apical one. Typical patterns are presented for apical (apical) and basal (basal)... |
PMC1079943_F5_1753.jpg | What is the core subject represented in this visual? | Lung of SH rat exposed to 3 mg/kg (a) or 10 mg/kg (b) of RTD. A significant dose-effect relationship is seen for the number of macrophages loaded with PM after exposure to RTD. Slight to moderate quantities of PM are phagocytised by a small number of alveolar macrophages after exposure to the lower RTD dose (a; arrows)... |
PMC1079943_F5_1754.jpg | What is the central feature of this picture? | Lung of SH rat exposed to 3 mg/kg (a) or 10 mg/kg (b) of RTD. A significant dose-effect relationship is seen for the number of macrophages loaded with PM after exposure to RTD. Slight to moderate quantities of PM are phagocytised by a small number of alveolar macrophages after exposure to the lower RTD dose (a; arrows)... |
PMC1079961_F3_1772.jpg | What's the most prominent thing you notice in this picture? | Intracellular localization of replicated plasmid containing tandem lacO repeats by staining with an MPB-lacI fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing lacO tandem repeats and 24 h later were infected with 3 PFU per cell of vV5D4 expressing V5-tagged uracil DNA glycosylase. At 12 h after... |
PMC1079961_F3_1770.jpg | What stands out most in this visual? | Intracellular localization of replicated plasmid containing tandem lacO repeats by staining with an MPB-lacI fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing lacO tandem repeats and 24 h later were infected with 3 PFU per cell of vV5D4 expressing V5-tagged uracil DNA glycosylase. At 12 h after... |
PMC1079961_F3_1768.jpg | What is being portrayed in this visual content? | Intracellular localization of replicated plasmid containing tandem lacO repeats by staining with an MPB-lacI fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing lacO tandem repeats and 24 h later were infected with 3 PFU per cell of vV5D4 expressing V5-tagged uracil DNA glycosylase. At 12 h after... |
PMC1079961_F4_1755.jpg | What is the core subject represented in this visual? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1757.jpg | Can you identify the primary element in this image? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1763.jpg | What is the dominant medical problem in this image? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1766.jpg | What key item or scene is captured in this photo? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1756.jpg | What is the main focus of this visual representation? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1760.jpg | What does this image primarily show? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1764.jpg | What is the principal component of this image? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1762.jpg | What is the main focus of this visual representation? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1758.jpg | What is the principal component of this image? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1759.jpg | What is shown in this image? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1079961_F4_1761.jpg | What is the dominant medical problem in this image? | Intracellular localization of replicated plasmid containing tandem lacO repeats using a lacI-GFP fusion protein. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lacO repeats (top 2 panels) or p716 control plasmid (bottom 2 panels) and infected with vGFP-lacI. At 12 h after infection, cells were fixed,... |
PMC1082910_F1_1773.jpg | What does this image primarily show? | Immunohistochemical staining for STS of cumulus cells1A: ×400, 1B: ×1000 STS expression was present in all 9 samples of human cumulus cells that were immunohistochemically stained. The cytoplasm of the cumulus cells was stained by anti-human STS polyclonal antibody. |
PMC1082910_F1_1774.jpg | What is shown in this image? | Immunohistochemical staining for STS of cumulus cells1A: ×400, 1B: ×1000 STS expression was present in all 9 samples of human cumulus cells that were immunohistochemically stained. The cytoplasm of the cumulus cells was stained by anti-human STS polyclonal antibody. |
PMC1082912_F1_1775.jpg | What is the dominant medical problem in this image? | Ultrasonographic image of the case, monochorionic triamniotic triplet pregnancy, is demonstrating single chorionic cavity at 6 weeks of gestation (arrows). |
PMC1082912_F4_1778.jpg | What's the most prominent thing you notice in this picture? | Computerized tomography of the infant at 3 months: two cystic masses in the middle lobe of the right lung, suggesting congenital cystic adenomatoid malformation (arrows). |
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