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PMC2409183_fig7_23643.jpg | What can you see in this picture? | Mutation of Arg86 or Arg196 to glutamine or glutamate does not prevent MCT1 from being correctly targeted to the plasma membrane of COS cells. COS cells were co-transfected with MCT1-c-CFP and basigin-c-YFP constructs containing the mutations indicated and live cell imaging performed as described under ‘Methods’. This ... |
PMC2409183_fig7_23648.jpg | What is the principal component of this image? | Mutation of Arg86 or Arg196 to glutamine or glutamate does not prevent MCT1 from being correctly targeted to the plasma membrane of COS cells. COS cells were co-transfected with MCT1-c-CFP and basigin-c-YFP constructs containing the mutations indicated and live cell imaging performed as described under ‘Methods’. This ... |
PMC2409183_fig7_23641.jpg | Can you identify the primary element in this image? | Mutation of Arg86 or Arg196 to glutamine or glutamate does not prevent MCT1 from being correctly targeted to the plasma membrane of COS cells. COS cells were co-transfected with MCT1-c-CFP and basigin-c-YFP constructs containing the mutations indicated and live cell imaging performed as described under ‘Methods’. This ... |
PMC2409311_F1_23657.jpg | Can you identify the primary element in this image? | Effects of COX-2 deficiency on LPS-induced neuronal degeneration. Representative photomicrographs of FluoroJade-B staining in the hippocampus of COX-2+/+ and COX-2-/- mice 24 h after icv injection of LPS or vehicle. High magnification (10×) images of FluoroJade-B staining in the hippocampus are shown. The inset shows d... |
PMC2409311_F1_23656.jpg | What is the central feature of this picture? | Effects of COX-2 deficiency on LPS-induced neuronal degeneration. Representative photomicrographs of FluoroJade-B staining in the hippocampus of COX-2+/+ and COX-2-/- mice 24 h after icv injection of LPS or vehicle. High magnification (10×) images of FluoroJade-B staining in the hippocampus are shown. The inset shows d... |
PMC2409311_F1_23655.jpg | What key item or scene is captured in this photo? | Effects of COX-2 deficiency on LPS-induced neuronal degeneration. Representative photomicrographs of FluoroJade-B staining in the hippocampus of COX-2+/+ and COX-2-/- mice 24 h after icv injection of LPS or vehicle. High magnification (10×) images of FluoroJade-B staining in the hippocampus are shown. The inset shows d... |
PMC2409313_F4_23670.jpg | What is the focal point of this photograph? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23666.jpg | What can you see in this picture? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23667.jpg | What is the main focus of this visual representation? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23661.jpg | What key item or scene is captured in this photo? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23664.jpg | What is the core subject represented in this visual? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23658.jpg | What stands out most in this visual? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23673.jpg | What can you see in this picture? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23662.jpg | What is being portrayed in this visual content? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23660.jpg | What is being portrayed in this visual content? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409313_F4_23659.jpg | What key item or scene is captured in this photo? | Immunohistochemical analysis of WT E14 ES cells and E14 overexpressing, Nanog, Pem and Pramel7. IHC analysis with OCT-3/4 and SSEA-1 and staining for alkaline phosphatase were performed after cultivation of the cells for 8 days without adding LIF to the medium. E14 ES cells differentiated under these conditions and los... |
PMC2409322_F6_23677.jpg | What is the core subject represented in this visual? | Time lapse observations of the dendrite elongating. Stills from two films (times given in hours and minutes APF), above an anterior zone bristle is shown, and below a posterior zone one; the stills are aligned with respect to the termination of the dendrites. The images show elongation of the dendrites. On the distal s... |
PMC2409322_F6_23676.jpg | Can you identify the primary element in this image? | Time lapse observations of the dendrite elongating. Stills from two films (times given in hours and minutes APF), above an anterior zone bristle is shown, and below a posterior zone one; the stills are aligned with respect to the termination of the dendrites. The images show elongation of the dendrites. On the distal s... |
PMC2409322_F6_23681.jpg | What is the main focus of this visual representation? | Time lapse observations of the dendrite elongating. Stills from two films (times given in hours and minutes APF), above an anterior zone bristle is shown, and below a posterior zone one; the stills are aligned with respect to the termination of the dendrites. The images show elongation of the dendrites. On the distal s... |
PMC2409322_F6_23678.jpg | Can you identify the primary element in this image? | Time lapse observations of the dendrite elongating. Stills from two films (times given in hours and minutes APF), above an anterior zone bristle is shown, and below a posterior zone one; the stills are aligned with respect to the termination of the dendrites. The images show elongation of the dendrites. On the distal s... |
PMC2409322_F6_23675.jpg | What is the core subject represented in this visual? | Time lapse observations of the dendrite elongating. Stills from two films (times given in hours and minutes APF), above an anterior zone bristle is shown, and below a posterior zone one; the stills are aligned with respect to the termination of the dendrites. The images show elongation of the dendrites. On the distal s... |
PMC2409322_F6_23680.jpg | What is the central feature of this picture? | Time lapse observations of the dendrite elongating. Stills from two films (times given in hours and minutes APF), above an anterior zone bristle is shown, and below a posterior zone one; the stills are aligned with respect to the termination of the dendrites. The images show elongation of the dendrites. On the distal s... |
PMC2409322_F6_23679.jpg | What does this image primarily show? | Time lapse observations of the dendrite elongating. Stills from two films (times given in hours and minutes APF), above an anterior zone bristle is shown, and below a posterior zone one; the stills are aligned with respect to the termination of the dendrites. The images show elongation of the dendrites. On the distal s... |
PMC2409331_F1_23682.jpg | What is the dominant medical problem in this image? | A CT scan section of case 2, showing severe stenosis of left main bronchus. |
PMC2409332_F1_23683.jpg | Describe the main subject of this image. | Chest radiograph showing a raised left hemi-diaphragm and volume loss in the left lower lobe. |
PMC2409332_F2_23684.jpg | What key item or scene is captured in this photo? | CT scan depicting a well circumscribed tumor measuring 10 cm antero-posteriorly, 14 cm transversely and 9 cm cranio-caudally enveloping the descending aorta and extending into the posterior mediastinum. |
PMC2409333_F3_23687.jpg | What is the dominant medical problem in this image? | Microscopic imaging of the tumor at 10×, 20×, 40× shown with H&E staining. |
PMC2409333_F3_23689.jpg | What's the most prominent thing you notice in this picture? | Microscopic imaging of the tumor at 10×, 20×, 40× shown with H&E staining. |
PMC2409333_F3_23688.jpg | What is the main focus of this visual representation? | Microscopic imaging of the tumor at 10×, 20×, 40× shown with H&E staining. |
PMC2409334_F2_23692.jpg | What is the core subject represented in this visual? | Partial Response with significantly reduced uptake on PET. |
PMC2409334_F2_23691.jpg | What is the central feature of this picture? | Partial Response with significantly reduced uptake on PET. |
PMC2409353_F1_23693.jpg | What stands out most in this visual? | The suspicious lesion and the vacuum-assisted breast biopsy probe underneath the skin. |
PMC2409354_F1_23696.jpg | What's the most prominent thing you notice in this picture? | Photomicrograph of the renal biopsy showing prominent fibrocellular crescent formation and moderate mesangial proliferation in a glomerulus. Hematoxylin and eosin stain. |
PMC2409354_F2_23694.jpg | What stands out most in this visual? | Photomicrograph of renal biopsy showing crescent formation and tuft narrowing. Periodic acid silver methanamine stain. |
PMC2409354_F3_23695.jpg | What is the principal component of this image? | Photomicrograph of the renal biopsy showing prominent fibrocellular crescent formation. Chronic inflammatory cellular infiltration and fibrosis is also evident in the interstitium. Periodic acid-Schiff stain. |
PMC2409359_F6_23700.jpg | What is being portrayed in this visual content? | Microscopic features at high magnification included (A) the high number of pleomorphic cells with frequent mitosis and (B) the focally fused cells with central nucleus (hematoxylin and eosin, × 400). (C) Immunohistochemical staining Caldesmon. According to this technique a diagnosis of grade III LMS was made (caldesmon... |
PMC2409359_F6_23699.jpg | What object or scene is depicted here? | Microscopic features at high magnification included (A) the high number of pleomorphic cells with frequent mitosis and (B) the focally fused cells with central nucleus (hematoxylin and eosin, × 400). (C) Immunohistochemical staining Caldesmon. According to this technique a diagnosis of grade III LMS was made (caldesmon... |
PMC2409361_F1_23697.jpg | What is the central feature of this picture? | Left breast mammogram (L-mlo) view shows dense lobulated nodule at the upper inner quadrant (arrow). |
PMC2409368_F3_23705.jpg | What does this image primarily show? | Event related synchronizations Changes in the gamma frequency band during swallowing Please note that the range of the t-value varies between the three figures. a) with persisting dysphagia a strong gamma synchronization of the right insula can be found. b) after clinical recovery of swallowing ability the insula activ... |
PMC2409368_F3_23706.jpg | What is shown in this image? | Event related synchronizations Changes in the gamma frequency band during swallowing Please note that the range of the t-value varies between the three figures. a) with persisting dysphagia a strong gamma synchronization of the right insula can be found. b) after clinical recovery of swallowing ability the insula activ... |
PMC2409368_F3_23703.jpg | What is the principal component of this image? | Event related synchronizations Changes in the gamma frequency band during swallowing Please note that the range of the t-value varies between the three figures. a) with persisting dysphagia a strong gamma synchronization of the right insula can be found. b) after clinical recovery of swallowing ability the insula activ... |
PMC2409368_F3_23704.jpg | What is the core subject represented in this visual? | Event related synchronizations Changes in the gamma frequency band during swallowing Please note that the range of the t-value varies between the three figures. a) with persisting dysphagia a strong gamma synchronization of the right insula can be found. b) after clinical recovery of swallowing ability the insula activ... |
PMC2409368_F3_23701.jpg | What is being portrayed in this visual content? | Event related synchronizations Changes in the gamma frequency band during swallowing Please note that the range of the t-value varies between the three figures. a) with persisting dysphagia a strong gamma synchronization of the right insula can be found. b) after clinical recovery of swallowing ability the insula activ... |
PMC2409444_F2_23708.jpg | Can you identify the primary element in this image? | Structural characteristics of mouse liver parenchyma perfused in vitro with 0.25 mg of colloidal carbon/mL in the (A) absence and (B) presence of 30 micrograms /mL of beta2-glycoprotein I (beta2GPI). Haematoxylin-eosin. |
PMC2409444_F2_23707.jpg | What does this image primarily show? | Structural characteristics of mouse liver parenchyma perfused in vitro with 0.25 mg of colloidal carbon/mL in the (A) absence and (B) presence of 30 micrograms /mL of beta2-glycoprotein I (beta2GPI). Haematoxylin-eosin. |
PMC2409448_F5_23709.jpg | What object or scene is depicted here? | Immunohistochemistry for fibrillin-1 in focal nodular hyperplasia. Higher magnification of the area defined by a rectangle in the Figure 4. Fibrillin-1 staining is stronger close to the basement membrane of biliary ductules (white arrow) in the fibrous septa and around sinusoids near the septa (black arrow). |
PMC2409454_fig3_23712.jpg | What is shown in this image? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23720.jpg | What does this image primarily show? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23721.jpg | What is shown in this image? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23718.jpg | What is the central feature of this picture? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23711.jpg | Describe the main subject of this image. | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23714.jpg | What is the focal point of this photograph? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23715.jpg | What's the most prominent thing you notice in this picture? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23719.jpg | What does this image primarily show? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23716.jpg | What object or scene is depicted here? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23710.jpg | What is the central feature of this picture? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409454_fig3_23713.jpg | What is the dominant medical problem in this image? | (A) Haematoxylin and eosin stained sections of organotypic raft cultures of PHKs transduced with retrovirus expressing HPV-16 E7 mutant proteins. Magnification × 400. (B) Interphase cytogenetic staining of a raft culture section from each of the three morphological categories with a chromosome 17 specific probe. Nuclei... |
PMC2409485_fig1_23723.jpg | What is the core subject represented in this visual? | Response to imatinib treatment. Computed tomographic examination before imatinib treatment: a solitary liver metastasis (arrow) and multiple peritoneal metastases (arrowheads) (A), CT scan after 6 months of imatinib treatment showing a partial response (B), gadolinium-enhanced T1-weighted MRI after 9 months of imatinib... |
PMC2409485_fig1_23722.jpg | What stands out most in this visual? | Response to imatinib treatment. Computed tomographic examination before imatinib treatment: a solitary liver metastasis (arrow) and multiple peritoneal metastases (arrowheads) (A), CT scan after 6 months of imatinib treatment showing a partial response (B), gadolinium-enhanced T1-weighted MRI after 9 months of imatinib... |
PMC2409485_fig1_23724.jpg | What is being portrayed in this visual content? | Response to imatinib treatment. Computed tomographic examination before imatinib treatment: a solitary liver metastasis (arrow) and multiple peritoneal metastases (arrowheads) (A), CT scan after 6 months of imatinib treatment showing a partial response (B), gadolinium-enhanced T1-weighted MRI after 9 months of imatinib... |
PMC2409522_fig2_23726.jpg | What is the dominant medical problem in this image? | Sagittal T2-weighted fast spin-echo (FSE 3000/88 ms (TR/effective TE)) images before (A) and after (B) three cycles of neoadjuvant chemotherapy. The intermediate signal intensity tumour confined to the cervix (arrows) reduced from 50 to 18 cm3 in volume. |
PMC2409522_fig2_23727.jpg | What is the main focus of this visual representation? | Sagittal T2-weighted fast spin-echo (FSE 3000/88 ms (TR/effective TE)) images before (A) and after (B) three cycles of neoadjuvant chemotherapy. The intermediate signal intensity tumour confined to the cervix (arrows) reduced from 50 to 18 cm3 in volume. |
PMC2409525_fig1_23730.jpg | What is the core subject represented in this visual? | TP expression status of pre- and post-treatment. (A) An invasive ductal carcinoma: TP expression was upregulated remarkably by the treatment with FEC (5-FU, epirubicin, and cyclophosphamide) followed by docetaxel. Tumour TP score: pretreatment; 0 (upper), post-treatment; 7 (bottom), yielding a score difference of 7. Th... |
PMC2409525_fig1_23729.jpg | What is the principal component of this image? | TP expression status of pre- and post-treatment. (A) An invasive ductal carcinoma: TP expression was upregulated remarkably by the treatment with FEC (5-FU, epirubicin, and cyclophosphamide) followed by docetaxel. Tumour TP score: pretreatment; 0 (upper), post-treatment; 7 (bottom), yielding a score difference of 7. Th... |
PMC2409525_fig1_23731.jpg | What is the central feature of this picture? | TP expression status of pre- and post-treatment. (A) An invasive ductal carcinoma: TP expression was upregulated remarkably by the treatment with FEC (5-FU, epirubicin, and cyclophosphamide) followed by docetaxel. Tumour TP score: pretreatment; 0 (upper), post-treatment; 7 (bottom), yielding a score difference of 7. Th... |
PMC2409526_fig4_23732.jpg | What can you see in this picture? | Immunofluorescence analysis of nuclear hMre11 and Rad50 foci in irradiated skin fibroblasts derived from a healthy individual (HFIB1, top) and from a hypersensitive cancer patient (HS5, bottom). Cells were irradiated with 8 Gy, fixed 2 h postirradiation and double stained with anti-hMre11 (red fluorescence) and anti-Ra... |
PMC2409526_fig4_23736.jpg | What's the most prominent thing you notice in this picture? | Immunofluorescence analysis of nuclear hMre11 and Rad50 foci in irradiated skin fibroblasts derived from a healthy individual (HFIB1, top) and from a hypersensitive cancer patient (HS5, bottom). Cells were irradiated with 8 Gy, fixed 2 h postirradiation and double stained with anti-hMre11 (red fluorescence) and anti-Ra... |
PMC2409526_fig4_23733.jpg | What is shown in this image? | Immunofluorescence analysis of nuclear hMre11 and Rad50 foci in irradiated skin fibroblasts derived from a healthy individual (HFIB1, top) and from a hypersensitive cancer patient (HS5, bottom). Cells were irradiated with 8 Gy, fixed 2 h postirradiation and double stained with anti-hMre11 (red fluorescence) and anti-Ra... |
PMC2409526_fig4_23734.jpg | What's the most prominent thing you notice in this picture? | Immunofluorescence analysis of nuclear hMre11 and Rad50 foci in irradiated skin fibroblasts derived from a healthy individual (HFIB1, top) and from a hypersensitive cancer patient (HS5, bottom). Cells were irradiated with 8 Gy, fixed 2 h postirradiation and double stained with anti-hMre11 (red fluorescence) and anti-Ra... |
PMC2409526_fig4_23737.jpg | What is the focal point of this photograph? | Immunofluorescence analysis of nuclear hMre11 and Rad50 foci in irradiated skin fibroblasts derived from a healthy individual (HFIB1, top) and from a hypersensitive cancer patient (HS5, bottom). Cells were irradiated with 8 Gy, fixed 2 h postirradiation and double stained with anti-hMre11 (red fluorescence) and anti-Ra... |
PMC2409527_fig3_23738.jpg | What is the principal component of this image? | Changes in the immunostaining pattern of protein tyrosine nitration between normal human kidney/benign tumour and RCC. Immunodetection of 3-nitrotyrosine on paraffin sections. (A) In normal renal parenchyma, most of the tubular epithelial cells along the nephron were labelled, with a variable staining intensity. In glo... |
PMC2409527_fig3_23739.jpg | What is the main focus of this visual representation? | Changes in the immunostaining pattern of protein tyrosine nitration between normal human kidney/benign tumour and RCC. Immunodetection of 3-nitrotyrosine on paraffin sections. (A) In normal renal parenchyma, most of the tubular epithelial cells along the nephron were labelled, with a variable staining intensity. In glo... |
PMC2409535_fig3_23742.jpg | What is the focal point of this photograph? | Macroscopic observations on day 12 of the effect of aplidine on tumour xenograft-induced CAM vascularisation. Fragments of the same bioptic specimen from 1A9-VS4 tumours were grafted onto the CAM on day 8 in the absence (A) or presence of aplidine (B), and incubated for 4 days. A reduction in the number of blood vessel... |
PMC2409535_fig3_23741.jpg | What is the principal component of this image? | Macroscopic observations on day 12 of the effect of aplidine on tumour xenograft-induced CAM vascularisation. Fragments of the same bioptic specimen from 1A9-VS4 tumours were grafted onto the CAM on day 8 in the absence (A) or presence of aplidine (B), and incubated for 4 days. A reduction in the number of blood vessel... |
PMC2409572_fig2_23745.jpg | What is the focal point of this photograph? | Prostate cancer microtumours growing on the CAM. (A) In the mock-treated control, only very few cells of the tumour, sitting on top of the CAM, show signs of apoptosis. (B) Strong labelling (red staining) of tumour cells by immunohistochemistry with an anti-human antibody to demonstrate the human origin of the evaluate... |
PMC2409572_fig2_23743.jpg | What is the dominant medical problem in this image? | Prostate cancer microtumours growing on the CAM. (A) In the mock-treated control, only very few cells of the tumour, sitting on top of the CAM, show signs of apoptosis. (B) Strong labelling (red staining) of tumour cells by immunohistochemistry with an anti-human antibody to demonstrate the human origin of the evaluate... |
PMC2409572_fig2_23744.jpg | What key item or scene is captured in this photo? | Prostate cancer microtumours growing on the CAM. (A) In the mock-treated control, only very few cells of the tumour, sitting on top of the CAM, show signs of apoptosis. (B) Strong labelling (red staining) of tumour cells by immunohistochemistry with an anti-human antibody to demonstrate the human origin of the evaluate... |
PMC2409572_fig2_23746.jpg | Describe the main subject of this image. | Prostate cancer microtumours growing on the CAM. (A) In the mock-treated control, only very few cells of the tumour, sitting on top of the CAM, show signs of apoptosis. (B) Strong labelling (red staining) of tumour cells by immunohistochemistry with an anti-human antibody to demonstrate the human origin of the evaluate... |
PMC2409592_fig1_23747.jpg | What is the main focus of this visual representation? | Histology of human prostate cancer after xenografting, PAC120 and HID variants. (A) PAC120, compact with glandular differentiation (HES × 200). (B) HID28, a microscopic pattern similar to that of the PAC120 tumour (HES × 200). (C) HID16, focal neuroendocrine-like pattern (HES × 200). (D) HID25, a fully mucoid adenocarc... |
PMC2409592_fig1_23750.jpg | What is the central feature of this picture? | Histology of human prostate cancer after xenografting, PAC120 and HID variants. (A) PAC120, compact with glandular differentiation (HES × 200). (B) HID28, a microscopic pattern similar to that of the PAC120 tumour (HES × 200). (C) HID16, focal neuroendocrine-like pattern (HES × 200). (D) HID25, a fully mucoid adenocarc... |
PMC2409592_fig1_23748.jpg | What is being portrayed in this visual content? | Histology of human prostate cancer after xenografting, PAC120 and HID variants. (A) PAC120, compact with glandular differentiation (HES × 200). (B) HID28, a microscopic pattern similar to that of the PAC120 tumour (HES × 200). (C) HID16, focal neuroendocrine-like pattern (HES × 200). (D) HID25, a fully mucoid adenocarc... |
PMC2409592_fig1_23749.jpg | What key item or scene is captured in this photo? | Histology of human prostate cancer after xenografting, PAC120 and HID variants. (A) PAC120, compact with glandular differentiation (HES × 200). (B) HID28, a microscopic pattern similar to that of the PAC120 tumour (HES × 200). (C) HID16, focal neuroendocrine-like pattern (HES × 200). (D) HID25, a fully mucoid adenocarc... |
PMC2409630_fig3_23754.jpg | What is the principal component of this image? | Effect of yessotoxin on morphology of MCF-7 cells in culture. Phase contrast microscopy (magnification × 200) of MCF-7 cells after treatment for 4 days with vehicle (A) or 1 nM YTX (B). |
PMC2409652_fig4_23756.jpg | What is the dominant medical problem in this image? | Microscopic features of stable transfectant in HepG2 cells. (A) control; (B) Snail; (C) SIP1. Photographs were taken at a magnification of ×200. The morphologic alteration to fibroblastoid features was observed in Snail and SIP1 transfectants compared with control cells. |
PMC2409652_fig4_23758.jpg | What is the principal component of this image? | Microscopic features of stable transfectant in HepG2 cells. (A) control; (B) Snail; (C) SIP1. Photographs were taken at a magnification of ×200. The morphologic alteration to fibroblastoid features was observed in Snail and SIP1 transfectants compared with control cells. |
PMC2409676_fig1_23760.jpg | What is shown in this image? | (A) Micrograph of Gaffchromic film illuminated with 400 Gy ultrasoft X-rays, demonstrating a sharply defined region of irradiation. Bar represents 100 μm. (B) Fluorescently labelled cells were overlaid on the film to demonstrate how many cells are exposed to ultrasoft X-rays and confirm that translation from the X-ray ... |
PMC2409686_fig4_23763.jpg | What is the central feature of this picture? | FasL/Fas interaction in tumour-mediated mesothelial apoptosis. Dual confocal fluorescent microscopy of co-cultures with anti-FasL and anti-Fas antibodies. FasL and Fas were visualised with a TRITC and FITC secondary antibody respectively. Mesothelial cells demonstrate homogenous cell surface expression of Fas (A) and u... |
PMC2409686_fig4_23762.jpg | Can you identify the primary element in this image? | FasL/Fas interaction in tumour-mediated mesothelial apoptosis. Dual confocal fluorescent microscopy of co-cultures with anti-FasL and anti-Fas antibodies. FasL and Fas were visualised with a TRITC and FITC secondary antibody respectively. Mesothelial cells demonstrate homogenous cell surface expression of Fas (A) and u... |
PMC2409692_fig3_23768.jpg | What is the central feature of this picture? | A subtracted image of a large tumour of the left breast before and after neoadjuvant chemotherapy. (A) and (B) reconstructed in the axial plane, (C) and (D) in the coronal plane. The patient was aged 52 years, had a clinically immeasurable tumour involving the nipple and so not suitable for WLE. It was grade 3, ER posi... |
PMC2409692_fig3_23765.jpg | What is the focal point of this photograph? | A subtracted image of a large tumour of the left breast before and after neoadjuvant chemotherapy. (A) and (B) reconstructed in the axial plane, (C) and (D) in the coronal plane. The patient was aged 52 years, had a clinically immeasurable tumour involving the nipple and so not suitable for WLE. It was grade 3, ER posi... |
PMC2409718_fig1_23777.jpg | What is the focal point of this photograph? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409718_fig1_23776.jpg | What can you see in this picture? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409718_fig1_23778.jpg | What key item or scene is captured in this photo? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409718_fig1_23772.jpg | What is the core subject represented in this visual? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409718_fig1_23773.jpg | What can you see in this picture? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409718_fig1_23775.jpg | What does this image primarily show? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409718_fig1_23774.jpg | What's the most prominent thing you notice in this picture? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409718_fig1_23771.jpg | What is the main focus of this visual representation? | Endometrioid adenocarcinoma (case patient 1), obliterating the lumen of the fallopian tube with a diameter of 2.5 mm (haematoxylin (H&E)), magnification × 50). (B) Negative P53 staining of the same tumour in (A) (magnification × 200). (C) Microscopic serous papillary adenocarcinoma (case patient 2), 1.0 cm in diameter ... |
PMC2409764_fig1_23780.jpg | What is the main focus of this visual representation? | Pimonidazole staining photographs (made with Carl Zeiss KS100 Software). (A) Peripheral view. (B) Central view. Both slices are shown on a magnification × 25. Scale bar is 40 μm. Abbreviations: N=necrosis, V=viable, well-oxygenated tumour tissue, P=PIMO-positive staining and the arrow indicates a blood vessel. |
PMC2409777_fig1_23785.jpg | What does this image primarily show? | Occurrence of nuclear proTGFα in human and rat hepatocarcinogenesis. (A–C) Rat liver 12 months post-NNM: serial sections of a preneoplastic lesion stained for GSTp (A) and TGFα (B); (C) HCC with proTGFα-pos nuclei (C). (D) Preneoplastic GSTp+ hepatocytes (violet) with proTGFα-pos nucleus (brown) and incorporated 3H-thy... |
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