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PMC1175070_F1_2456.jpg
What is the core subject represented in this visual?
Tumor cell diapedesis through human microvascular endothelial cell (HMVEC) monolayers. HBL100 cells were pre-labeled with dioctadecyl-3, 3,3', 3'-tetramethylindocarbocyanine percholate (DiI; red), co-cultured with HMVEC monolayers for various time periods, fixed with paraformaldehyde and labeled for F-actin (green). Op...
PMC1175070_F1_2458.jpg
What is the core subject represented in this visual?
Tumor cell diapedesis through human microvascular endothelial cell (HMVEC) monolayers. HBL100 cells were pre-labeled with dioctadecyl-3, 3,3', 3'-tetramethylindocarbocyanine percholate (DiI; red), co-cultured with HMVEC monolayers for various time periods, fixed with paraformaldehyde and labeled for F-actin (green). Op...
PMC1175083_F3_2472.jpg
What is being portrayed in this visual content?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2477.jpg
What stands out most in this visual?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2480.jpg
What does this image primarily show?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2475.jpg
Can you identify the primary element in this image?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2473.jpg
What stands out most in this visual?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2469.jpg
What key item or scene is captured in this photo?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2470.jpg
What stands out most in this visual?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2474.jpg
What can you see in this picture?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2478.jpg
What is the focal point of this photograph?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2476.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175083_F3_2479.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical detection of MMP11 and MMP12 by cervical tissue microarrays. A) Breast cancer sample (as positive control for MMP11 staining), B) negative control; a CC sample without primary antibody, C) one normal cervical tissue showing negative staining for MMP11, D) LSIL which presents positive immunostaining ...
PMC1175090_F5_2485.jpg
What can you see in this picture?
Immunohistochemistry for MCP-1 and the macrophage marker ED-1. Panel A-D: examples of photomicrographs of MCP-1 staining (brown) in glomeruli, hematoxylin counterstain (blue nuclei) Panel A (glomerulus of a normotensive normoglycemic rat) represents score 0, panel B (from a normotensive diabetic rat) score 1, panel C (...
PMC1175090_F5_2482.jpg
What is the central feature of this picture?
Immunohistochemistry for MCP-1 and the macrophage marker ED-1. Panel A-D: examples of photomicrographs of MCP-1 staining (brown) in glomeruli, hematoxylin counterstain (blue nuclei) Panel A (glomerulus of a normotensive normoglycemic rat) represents score 0, panel B (from a normotensive diabetic rat) score 1, panel C (...
PMC1175090_F5_2481.jpg
What key item or scene is captured in this photo?
Immunohistochemistry for MCP-1 and the macrophage marker ED-1. Panel A-D: examples of photomicrographs of MCP-1 staining (brown) in glomeruli, hematoxylin counterstain (blue nuclei) Panel A (glomerulus of a normotensive normoglycemic rat) represents score 0, panel B (from a normotensive diabetic rat) score 1, panel C (...
PMC1175090_F5_2483.jpg
What is the main focus of this visual representation?
Immunohistochemistry for MCP-1 and the macrophage marker ED-1. Panel A-D: examples of photomicrographs of MCP-1 staining (brown) in glomeruli, hematoxylin counterstain (blue nuclei) Panel A (glomerulus of a normotensive normoglycemic rat) represents score 0, panel B (from a normotensive diabetic rat) score 1, panel C (...
PMC1175090_F5_2484.jpg
What is the principal component of this image?
Immunohistochemistry for MCP-1 and the macrophage marker ED-1. Panel A-D: examples of photomicrographs of MCP-1 staining (brown) in glomeruli, hematoxylin counterstain (blue nuclei) Panel A (glomerulus of a normotensive normoglycemic rat) represents score 0, panel B (from a normotensive diabetic rat) score 1, panel C (...
PMC1175095_F1_2486.jpg
What is the dominant medical problem in this image?
Immunohistochemical analysis of tumor micoarrays. Representative normal human ovarian surface epithelium and tumor cores stained for TACC1 (panels A-E), and TACC3 (panels F-J) proteins to show positive and negative staining. TACC protein expression is detected as a brown signal against the blue Hematoxylin counterstain...
PMC1175095_F1_2494.jpg
What does this image primarily show?
Immunohistochemical analysis of tumor micoarrays. Representative normal human ovarian surface epithelium and tumor cores stained for TACC1 (panels A-E), and TACC3 (panels F-J) proteins to show positive and negative staining. TACC protein expression is detected as a brown signal against the blue Hematoxylin counterstain...
PMC1175095_F1_2492.jpg
What is shown in this image?
Immunohistochemical analysis of tumor micoarrays. Representative normal human ovarian surface epithelium and tumor cores stained for TACC1 (panels A-E), and TACC3 (panels F-J) proteins to show positive and negative staining. TACC protein expression is detected as a brown signal against the blue Hematoxylin counterstain...
PMC1175095_F1_2487.jpg
What is shown in this image?
Immunohistochemical analysis of tumor micoarrays. Representative normal human ovarian surface epithelium and tumor cores stained for TACC1 (panels A-E), and TACC3 (panels F-J) proteins to show positive and negative staining. TACC protein expression is detected as a brown signal against the blue Hematoxylin counterstain...
PMC1175095_F1_2488.jpg
What is being portrayed in this visual content?
Immunohistochemical analysis of tumor micoarrays. Representative normal human ovarian surface epithelium and tumor cores stained for TACC1 (panels A-E), and TACC3 (panels F-J) proteins to show positive and negative staining. TACC protein expression is detected as a brown signal against the blue Hematoxylin counterstain...
PMC1175095_F1_2495.jpg
Describe the main subject of this image.
Immunohistochemical analysis of tumor micoarrays. Representative normal human ovarian surface epithelium and tumor cores stained for TACC1 (panels A-E), and TACC3 (panels F-J) proteins to show positive and negative staining. TACC protein expression is detected as a brown signal against the blue Hematoxylin counterstain...
PMC1175820_pbio-0030265-g002_2500.jpg
What is the core subject represented in this visual?
Activation Pattern in V1 for Experiment 1Medio-posterior view on the inflated left occipital cortex of subject HP (A and B) and subject AK (C). All five subjects are shown in Figure S1. Gray-scale coloring of cortex indicates the extent of retinotopic visual areas (light gray: V1 and V3/VP; dark gray: V2, V4, and V3A) ...
PMC1175820_pbio-0030265-g002_2504.jpg
What's the most prominent thing you notice in this picture?
Activation Pattern in V1 for Experiment 1Medio-posterior view on the inflated left occipital cortex of subject HP (A and B) and subject AK (C). All five subjects are shown in Figure S1. Gray-scale coloring of cortex indicates the extent of retinotopic visual areas (light gray: V1 and V3/VP; dark gray: V2, V4, and V3A) ...
PMC1175820_pbio-0030265-g003_2496.jpg
What can you see in this picture?
Cortical Activation in V1 for Experiment 2(A) Left occipital cortex of subject HP (all five subjects are shown in Figure S2) with superimposed contrast maps indicating the cortical representation of the stimulus positions: upper (yellow), t(1445) > 15; middle (orange), t(1445) > 12; and lower (red), t(1445) > 9.3 (all ...
PMC1175820_pbio-0030265-g003_2497.jpg
What object or scene is depicted here?
Cortical Activation in V1 for Experiment 2(A) Left occipital cortex of subject HP (all five subjects are shown in Figure S2) with superimposed contrast maps indicating the cortical representation of the stimulus positions: upper (yellow), t(1445) > 15; middle (orange), t(1445) > 12; and lower (red), t(1445) > 9.3 (all ...
PMC1175820_pbio-0030265-g006_2507.jpg
What does this image primarily show?
Results from the Bistable Motion Quartet (Experiment 3)(A and B) Medio-posterior view on the inflated left occipital cortex of subject HP (A) and AK (B) (all six subjects are shown in Figure S3). Gray shading indicates the extension of V1 (light gray for V1) and the cortex curvature (dark gray, concave; light gray, con...
PMC1175820_pbio-0030265-g006_2506.jpg
Can you identify the primary element in this image?
Results from the Bistable Motion Quartet (Experiment 3)(A and B) Medio-posterior view on the inflated left occipital cortex of subject HP (A) and AK (B) (all six subjects are shown in Figure S3). Gray shading indicates the extension of V1 (light gray for V1) and the cortex curvature (dark gray, concave; light gray, con...
PMC1175842_F1_2512.jpg
What stands out most in this visual?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2515.jpg
What stands out most in this visual?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2517.jpg
What is being portrayed in this visual content?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2516.jpg
What is the focal point of this photograph?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2520.jpg
What can you see in this picture?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2519.jpg
What stands out most in this visual?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2510.jpg
Describe the main subject of this image.
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2526.jpg
What is the main focus of this visual representation?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2511.jpg
What is the dominant medical problem in this image?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2522.jpg
What key item or scene is captured in this photo?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2523.jpg
What is the main focus of this visual representation?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F1_2527.jpg
What is shown in this image?
Overview of 4D DIC microscope images of C. elegans embryo. (A) Schematic of 4D DIC microscope images. Digital images of a developing embryo were recorded in multiple focal planes and a set of multifocal images was recorded with a fixed time interval, α. (B) Example of 4D DIC microscope images of a C. elegans embryo. Ea...
PMC1175842_F3_2541.jpg
What is the core subject represented in this visual?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2548.jpg
What can you see in this picture?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2540.jpg
What is the core subject represented in this visual?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2543.jpg
What is the central feature of this picture?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2545.jpg
What object or scene is depicted here?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2547.jpg
What is the dominant medical problem in this image?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2546.jpg
What is being portrayed in this visual content?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2554.jpg
What is the dominant medical problem in this image?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2542.jpg
What is the main focus of this visual representation?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2550.jpg
What is shown in this image?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2552.jpg
What's the most prominent thing you notice in this picture?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2544.jpg
What does this image primarily show?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F3_2539.jpg
What is the core subject represented in this visual?
Low-entropy regions of different focal planes and different time points. (A – E and K–O) Input images. (F–J and P–T) Low-entropy regions (black) produced from the input images. Low-entropy regions were produced from multifocal images of an embryo at a specific time point in the four-cell stage with 4.5 μm between two f...
PMC1175842_F4_2535.jpg
What stands out most in this visual?
Overview of forward and backward trackings. Low-entropy regions selected by forward tracking are shown in the left column and those selected by backward tracking after the selection by forward tracking are shown in the right column. These low-entropy regions (white) are overlaid on their corresponding input images. Sol...
PMC1175842_F4_2534.jpg
What object or scene is depicted here?
Overview of forward and backward trackings. Low-entropy regions selected by forward tracking are shown in the left column and those selected by backward tracking after the selection by forward tracking are shown in the right column. These low-entropy regions (white) are overlaid on their corresponding input images. Sol...
PMC1175842_F4_2530.jpg
What does this image primarily show?
Overview of forward and backward trackings. Low-entropy regions selected by forward tracking are shown in the left column and those selected by backward tracking after the selection by forward tracking are shown in the right column. These low-entropy regions (white) are overlaid on their corresponding input images. Sol...
PMC1175842_F4_2531.jpg
Describe the main subject of this image.
Overview of forward and backward trackings. Low-entropy regions selected by forward tracking are shown in the left column and those selected by backward tracking after the selection by forward tracking are shown in the right column. These low-entropy regions (white) are overlaid on their corresponding input images. Sol...
PMC1175842_F4_2532.jpg
What is the focal point of this photograph?
Overview of forward and backward trackings. Low-entropy regions selected by forward tracking are shown in the left column and those selected by backward tracking after the selection by forward tracking are shown in the right column. These low-entropy regions (white) are overlaid on their corresponding input images. Sol...
PMC1175842_F4_2529.jpg
What key item or scene is captured in this photo?
Overview of forward and backward trackings. Low-entropy regions selected by forward tracking are shown in the left column and those selected by backward tracking after the selection by forward tracking are shown in the right column. These low-entropy regions (white) are overlaid on their corresponding input images. Sol...
PMC1175842_F4_2536.jpg
What is the dominant medical problem in this image?
Overview of forward and backward trackings. Low-entropy regions selected by forward tracking are shown in the left column and those selected by backward tracking after the selection by forward tracking are shown in the right column. These low-entropy regions (white) are overlaid on their corresponding input images. Sol...
PMC1175873_F1_2555.jpg
What is being portrayed in this visual content?
Histology samples from the three groups. (a) Normal pancreatic histology in group I (the sham operated group). (b) Light micrograph showing severe and extensive parenchymal necrosis, with few normal acinar cells in group II (the positive control group). (c) Light micrograph showing mild edema, parenchymal focal necrosi...
PMC1175873_F1_2556.jpg
Describe the main subject of this image.
Histology samples from the three groups. (a) Normal pancreatic histology in group I (the sham operated group). (b) Light micrograph showing severe and extensive parenchymal necrosis, with few normal acinar cells in group II (the positive control group). (c) Light micrograph showing mild edema, parenchymal focal necrosi...
PMC1177930_F4_2560.jpg
What object or scene is depicted here?
Light microscopy of hematoxylin and eosin-stained section of representative lungs from controls (A, B ) and treatment groups (XRT-WT vs. XRT-TG) at 3 wk (C, D ) and 14 wks (E, F ). Representative lung sections from XRT-WT exposed to 3 wk of radiation showing mild to moderate damage at 3 wk after radiation (C ), which g...
PMC1177930_F4_2559.jpg
What stands out most in this visual?
Light microscopy of hematoxylin and eosin-stained section of representative lungs from controls (A, B ) and treatment groups (XRT-WT vs. XRT-TG) at 3 wk (C, D ) and 14 wks (E, F ). Representative lung sections from XRT-WT exposed to 3 wk of radiation showing mild to moderate damage at 3 wk after radiation (C ), which g...
PMC1177930_F4_2558.jpg
Can you identify the primary element in this image?
Light microscopy of hematoxylin and eosin-stained section of representative lungs from controls (A, B ) and treatment groups (XRT-WT vs. XRT-TG) at 3 wk (C, D ) and 14 wks (E, F ). Representative lung sections from XRT-WT exposed to 3 wk of radiation showing mild to moderate damage at 3 wk after radiation (C ), which g...
PMC1177930_F4_2561.jpg
What's the most prominent thing you notice in this picture?
Light microscopy of hematoxylin and eosin-stained section of representative lungs from controls (A, B ) and treatment groups (XRT-WT vs. XRT-TG) at 3 wk (C, D ) and 14 wks (E, F ). Representative lung sections from XRT-WT exposed to 3 wk of radiation showing mild to moderate damage at 3 wk after radiation (C ), which g...
PMC1177934_F4_2565.jpg
What does this image primarily show?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2566.jpg
Can you identify the primary element in this image?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2577.jpg
What is being portrayed in this visual content?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2576.jpg
What is the focal point of this photograph?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2571.jpg
What key item or scene is captured in this photo?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2564.jpg
What is the dominant medical problem in this image?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2569.jpg
What stands out most in this visual?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2567.jpg
What is the core subject represented in this visual?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2575.jpg
What is the central feature of this picture?
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177934_F4_2572.jpg
Describe the main subject of this image.
Cellular localization of various Tim50a proteins. Hela cells were transfected with GFP-tagged proteins (first column), followed by staining with antibody Y12 (second column) to detect Sm proteins (snRNPs). The merged image in color is shown in the last column (GFP is green, Sm proteins are red). Arrows mark speckles wh...
PMC1177935_F1_2578.jpg
What is the central feature of this picture?
Chest roentgenogram upon admission. Frontal chest roentgenogram revealed extensive bilateral diffuse pulmonary infiltrations, left greater than right.
PMC1177971_F5_2579.jpg
What object or scene is depicted here?
BMS35S::R+35S::C1 cells have multiple vacuoles. Laser scanning confocal microscopy (false colored) images of (A) BMS and (B) BMS35S::R+35S::C1 cells loaded with 10 μM of the vacuolar dye BCECF-AM. Laser scanning confocal 'light transmitted' images of (C) BMS and (D) BMS35S::R+35S::C1 cells are shown in black and white....
PMC1177971_F5_2580.jpg
What is the principal component of this image?
BMS35S::R+35S::C1 cells have multiple vacuoles. Laser scanning confocal microscopy (false colored) images of (A) BMS and (B) BMS35S::R+35S::C1 cells loaded with 10 μM of the vacuolar dye BCECF-AM. Laser scanning confocal 'light transmitted' images of (C) BMS and (D) BMS35S::R+35S::C1 cells are shown in black and white....
PMC1177971_F5_2581.jpg
What key item or scene is captured in this photo?
BMS35S::R+35S::C1 cells have multiple vacuoles. Laser scanning confocal microscopy (false colored) images of (A) BMS and (B) BMS35S::R+35S::C1 cells loaded with 10 μM of the vacuolar dye BCECF-AM. Laser scanning confocal 'light transmitted' images of (C) BMS and (D) BMS35S::R+35S::C1 cells are shown in black and white....
PMC1177971_F5_2582.jpg
Describe the main subject of this image.
BMS35S::R+35S::C1 cells have multiple vacuoles. Laser scanning confocal microscopy (false colored) images of (A) BMS and (B) BMS35S::R+35S::C1 cells loaded with 10 μM of the vacuolar dye BCECF-AM. Laser scanning confocal 'light transmitted' images of (C) BMS and (D) BMS35S::R+35S::C1 cells are shown in black and white....
PMC1177971_F10_2589.jpg
What can you see in this picture?
Sub-cellular morphology of BI Pl maize floral cells accumulating anthocyanins. DIC images of a maize lemma from B-I/B-Peru plant over-accumulating anthocyanins. The above are extracted images from a time-lapse series (See Additional file 1: Movie 1). The time points on the images indicate the period from time 0' i.e. w...
PMC1177971_F10_2590.jpg
What is the principal component of this image?
Sub-cellular morphology of BI Pl maize floral cells accumulating anthocyanins. DIC images of a maize lemma from B-I/B-Peru plant over-accumulating anthocyanins. The above are extracted images from a time-lapse series (See Additional file 1: Movie 1). The time points on the images indicate the period from time 0' i.e. w...
PMC1177971_F10_2587.jpg
What key item or scene is captured in this photo?
Sub-cellular morphology of BI Pl maize floral cells accumulating anthocyanins. DIC images of a maize lemma from B-I/B-Peru plant over-accumulating anthocyanins. The above are extracted images from a time-lapse series (See Additional file 1: Movie 1). The time points on the images indicate the period from time 0' i.e. w...
PMC1177974_F2_2586.jpg
Can you identify the primary element in this image?
Normal and reactive hepatocytes: FNAB. (A) Hepatocytes show dense granular cytoplasm, round central nuclei, well-delineated nuclear membrane, distinct nucleoli, granular chromatin and binucleation. Note polymorphism displayed by nonneoplastic hepatocytes. The cells contain brown granules of lipofuscin pigment in the cy...
PMC1177974_F2_2585.jpg
What can you see in this picture?
Normal and reactive hepatocytes: FNAB. (A) Hepatocytes show dense granular cytoplasm, round central nuclei, well-delineated nuclear membrane, distinct nucleoli, granular chromatin and binucleation. Note polymorphism displayed by nonneoplastic hepatocytes. The cells contain brown granules of lipofuscin pigment in the cy...
PMC1177974_F3_2583.jpg
What is the dominant medical problem in this image?
Hepatocytes with large cell change: FNAB. There is simultaneous nuclear and cell enlargement of the hepatocytes, thus maintaining the nuclear-cytoplasmic ratio of 1/3. Note mild nuclear atypia (Papanicolaou).
PMC1177974_F5_2594.jpg
What does this image primarily show?
Well-differentiated hepatocellular carcinoma with trabecular and pseudoacinar patterns: FNAB. (A) Thick arborizing cords of malignant hepatocytes showing cellular monotony, increased nuclear-cytoplasmic ratio, and impression of nuclear crowding. The circular spaces among the cords represent pseudoacini (Papanicolaou). ...
PMC1177974_F5_2593.jpg
What is the focal point of this photograph?
Well-differentiated hepatocellular carcinoma with trabecular and pseudoacinar patterns: FNAB. (A) Thick arborizing cords of malignant hepatocytes showing cellular monotony, increased nuclear-cytoplasmic ratio, and impression of nuclear crowding. The circular spaces among the cords represent pseudoacini (Papanicolaou). ...
PMC1177974_F6_2598.jpg
What is the focal point of this photograph?
Moderately differentiated hepatocellular carcinoma: FNAB. Thick cords of malignant hepatocytes are wrapped by peripheral endothelium. They appear to be floating on transverse section view (Papanicolaou).
PMC1177974_F7_2601.jpg
What is the dominant medical problem in this image?
Moderately differentiated hepatocellular carcinoma with pseudoacinar pattern: FNAB. (A) Pseudoacini filled with bile which appears as dark brown blobs (Papanicolaou) (B) Bile appears black (May-Grunwald-Giemsa). (C) Corresponding histologic section of the tumor shows cystically dilated canaliculi filled with golden-bro...
PMC1177974_F7_2600.jpg
What is shown in this image?
Moderately differentiated hepatocellular carcinoma with pseudoacinar pattern: FNAB. (A) Pseudoacini filled with bile which appears as dark brown blobs (Papanicolaou) (B) Bile appears black (May-Grunwald-Giemsa). (C) Corresponding histologic section of the tumor shows cystically dilated canaliculi filled with golden-bro...
PMC1177974_F7_2599.jpg
What does this image primarily show?
Moderately differentiated hepatocellular carcinoma with pseudoacinar pattern: FNAB. (A) Pseudoacini filled with bile which appears as dark brown blobs (Papanicolaou) (B) Bile appears black (May-Grunwald-Giemsa). (C) Corresponding histologic section of the tumor shows cystically dilated canaliculi filled with golden-bro...
PMC1177974_F8_2592.jpg
Can you identify the primary element in this image?
Poorly differentiated hepatocellular carcinoma: FNAB. High-grade tumor shows marked pleomorphism but still retaining some hepatocytic characteristics (Papanicolaou).
PMC1177974_F9_2596.jpg
What is shown in this image?
Poorly differentiated hepatocellular carcinoma: FNAB. Atypical naked hepatocytic nuclei exhibit pleomorphism, thin nuclear membrane, nuclear contour irregularities, prominent nucleoli and multinucleation (Papanicolaou).
PMC1177974_F11_2595.jpg
What object or scene is depicted here?
Hepatocellular carcinoma: FNAB. The tumor cells stain positively for alpha-fetoprotein (Immunostain).
PMC1177991_F2_2603.jpg
What object or scene is depicted here?
Morphological changes induced by TGF-β1. A549 cells were incubated with 5 ng/ml of TGF-β1 for 48 h. (A) Untreated A549 cells show a pebble-like shape and cell-cell adhesion is clearly observed. (B) TGF-β1-treated cells show a decrease in cell-cell contacts and adopt a more elongated morphological shape (magnification o...
PMC1177991_F2_2602.jpg
Describe the main subject of this image.
Morphological changes induced by TGF-β1. A549 cells were incubated with 5 ng/ml of TGF-β1 for 48 h. (A) Untreated A549 cells show a pebble-like shape and cell-cell adhesion is clearly observed. (B) TGF-β1-treated cells show a decrease in cell-cell contacts and adopt a more elongated morphological shape (magnification o...