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PMC1287907_ppat-0010024-g004_3861.jpg | What's the most prominent thing you notice in this picture? | IIGP1 Associates Directly with the PVM; the Morphology of the Vacuolar IIGP1 Accumulation Changes in a Time-Dependent Manner(A) IFN-γ-induced astrocytes were infected with T. gondii for 6 h, fixed, and subjected to ultra-thin cryosectioning. Sections were labeled for IIGP1 using the 165 antiserum and 10 nm gold particl... |
PMC1287907_ppat-0010024-g008_3863.jpg | What stands out most in this visual? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3867.jpg | What's the most prominent thing you notice in this picture? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3872.jpg | What object or scene is depicted here? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3865.jpg | What is the focal point of this photograph? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3871.jpg | What key item or scene is captured in this photo? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3870.jpg | What stands out most in this visual? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3864.jpg | What can you see in this picture? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3874.jpg | What is the core subject represented in this visual? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3873.jpg | What object or scene is depicted here? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287907_ppat-0010024-g008_3866.jpg | What is shown in this image? | Induction of Autophagosomes in Vicinity of Disrupted VacuolesAstrocytes were transfected with pEGFP-C3-LC3 and induced with IFN-γ. Cells were infected with T. gondi 24 h later and fixed after 2 h (A) or 6 h (B, C, and D). In cells containing only smooth IIGP1 vacuoles GFP-LC3 remained diffusely distributed throughout t... |
PMC1287911_ppat-0010032-g004_3875.jpg | What is the central feature of this picture? |
Salmonella Induces Expression of SPI-2 in the Lumen of the Ileum(A) Mouse ileal loops were infected with either wild-type or invA
− PsseA RIVET strains for 15 min before the loops were removed and homogenized, and the percent resolution was determined.(B) Mouse ileal loops were infected with wild-type Salmonella for 1... |
PMC1289279_F1_3884.jpg | What is the central feature of this picture? | HSP60 positivity in carcinoma (arrow) but not in normal tissues (arrowhead) in specimens from both well differentiated (a) and poorly differentiated (b) tumours (Magnification: 10×). A higher magnification (40×) shows that the positivity is diffuse into cytoplasm of tumoral cells of both G1 (c) and G3 (d) specimens; fe... |
PMC1289279_F1_3885.jpg | What is the core subject represented in this visual? | HSP60 positivity in carcinoma (arrow) but not in normal tissues (arrowhead) in specimens from both well differentiated (a) and poorly differentiated (b) tumours (Magnification: 10×). A higher magnification (40×) shows that the positivity is diffuse into cytoplasm of tumoral cells of both G1 (c) and G3 (d) specimens; fe... |
PMC1289279_F1_3883.jpg | What can you see in this picture? | HSP60 positivity in carcinoma (arrow) but not in normal tissues (arrowhead) in specimens from both well differentiated (a) and poorly differentiated (b) tumours (Magnification: 10×). A higher magnification (40×) shows that the positivity is diffuse into cytoplasm of tumoral cells of both G1 (c) and G3 (d) specimens; fe... |
PMC1289279_F1_3888.jpg | What can you see in this picture? | HSP60 positivity in carcinoma (arrow) but not in normal tissues (arrowhead) in specimens from both well differentiated (a) and poorly differentiated (b) tumours (Magnification: 10×). A higher magnification (40×) shows that the positivity is diffuse into cytoplasm of tumoral cells of both G1 (c) and G3 (d) specimens; fe... |
PMC1289279_F3_3882.jpg | What stands out most in this visual? | Infiltrated lymph nodes from G1 (a) and G3 (b) LBC show tumoral glands positive for HSP60. Metastases also show glands positive for HSP10 in both G1 (c) and G3 (d) carcinomas (Magnification: 40×). HSP60 positivity shows vascular (e) and neural (f) invasion by cancer (Magnification: 10×). |
PMC1289279_F3_3879.jpg | What is the central feature of this picture? | Infiltrated lymph nodes from G1 (a) and G3 (b) LBC show tumoral glands positive for HSP60. Metastases also show glands positive for HSP10 in both G1 (c) and G3 (d) carcinomas (Magnification: 40×). HSP60 positivity shows vascular (e) and neural (f) invasion by cancer (Magnification: 10×). |
PMC1289279_F3_3877.jpg | What key item or scene is captured in this photo? | Infiltrated lymph nodes from G1 (a) and G3 (b) LBC show tumoral glands positive for HSP60. Metastases also show glands positive for HSP10 in both G1 (c) and G3 (d) carcinomas (Magnification: 40×). HSP60 positivity shows vascular (e) and neural (f) invasion by cancer (Magnification: 10×). |
PMC1289279_F3_3880.jpg | What is shown in this image? | Infiltrated lymph nodes from G1 (a) and G3 (b) LBC show tumoral glands positive for HSP60. Metastases also show glands positive for HSP10 in both G1 (c) and G3 (d) carcinomas (Magnification: 40×). HSP60 positivity shows vascular (e) and neural (f) invasion by cancer (Magnification: 10×). |
PMC1289279_F3_3881.jpg | What does this image primarily show? | Infiltrated lymph nodes from G1 (a) and G3 (b) LBC show tumoral glands positive for HSP60. Metastases also show glands positive for HSP10 in both G1 (c) and G3 (d) carcinomas (Magnification: 40×). HSP60 positivity shows vascular (e) and neural (f) invasion by cancer (Magnification: 10×). |
PMC1291371_F1_3912.jpg | What can you see in this picture? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3917.jpg | What does this image primarily show? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3918.jpg | What object or scene is depicted here? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3913.jpg | What is the main focus of this visual representation? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3916.jpg | What is the principal component of this image? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3914.jpg | What key item or scene is captured in this photo? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3910.jpg | Can you identify the primary element in this image? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3915.jpg | What is the main focus of this visual representation? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3907.jpg | What object or scene is depicted here? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3908.jpg | What is being portrayed in this visual content? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3909.jpg | Describe the main subject of this image. | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3906.jpg | What is being portrayed in this visual content? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3905.jpg | What is the dominant medical problem in this image? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F1_3911.jpg | Can you identify the primary element in this image? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in the renal cortex of the four groups of rats studied: Control (CT), thyroidectomized (HTX), ischemia and reperfusion (IR) and HTX+IR (100× magnification). |
PMC1291371_F4_3896.jpg | Can you identify the primary element in this image? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3894.jpg | What stands out most in this visual? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3902.jpg | What does this image primarily show? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3895.jpg | Describe the main subject of this image. | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3891.jpg | What is the main focus of this visual representation? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3904.jpg | What is the dominant medical problem in this image? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3890.jpg | Describe the main subject of this image. | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3901.jpg | What can you see in this picture? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3897.jpg | What is the focal point of this photograph? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3900.jpg | What is shown in this image? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291371_F4_3898.jpg | What is the central feature of this picture? | Representative images of histology (H&E) (first row) and immunohistochemical detection of 3-NT (second row), 4-HNE (third row) and DNP (fourth row) in renal medulla of the four groups of rats studied: CT, HTX, IR, and HTX+IR. (100× magnification). |
PMC1291400_F3_3922.jpg | What key item or scene is captured in this photo? | Immunohistochemical and in situ localisation of ghrelin and GHSR-1a in sheep gonads. Photomicrographs of sheep ovarian and testicular sections. (A) Ovarian section showing positive immunostaining for ghrelin in the stroma, primordial follicles (PF) and the ovarian surface epithelium (OSE). (B) Ovarian section showing p... |
PMC1291400_F3_3921.jpg | What is the dominant medical problem in this image? | Immunohistochemical and in situ localisation of ghrelin and GHSR-1a in sheep gonads. Photomicrographs of sheep ovarian and testicular sections. (A) Ovarian section showing positive immunostaining for ghrelin in the stroma, primordial follicles (PF) and the ovarian surface epithelium (OSE). (B) Ovarian section showing p... |
PMC1291400_F3_3927.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemical and in situ localisation of ghrelin and GHSR-1a in sheep gonads. Photomicrographs of sheep ovarian and testicular sections. (A) Ovarian section showing positive immunostaining for ghrelin in the stroma, primordial follicles (PF) and the ovarian surface epithelium (OSE). (B) Ovarian section showing p... |
PMC1291400_F3_3926.jpg | What key item or scene is captured in this photo? | Immunohistochemical and in situ localisation of ghrelin and GHSR-1a in sheep gonads. Photomicrographs of sheep ovarian and testicular sections. (A) Ovarian section showing positive immunostaining for ghrelin in the stroma, primordial follicles (PF) and the ovarian surface epithelium (OSE). (B) Ovarian section showing p... |
PMC1291400_F3_3923.jpg | Describe the main subject of this image. | Immunohistochemical and in situ localisation of ghrelin and GHSR-1a in sheep gonads. Photomicrographs of sheep ovarian and testicular sections. (A) Ovarian section showing positive immunostaining for ghrelin in the stroma, primordial follicles (PF) and the ovarian surface epithelium (OSE). (B) Ovarian section showing p... |
PMC1291400_F3_3925.jpg | What is being portrayed in this visual content? | Immunohistochemical and in situ localisation of ghrelin and GHSR-1a in sheep gonads. Photomicrographs of sheep ovarian and testicular sections. (A) Ovarian section showing positive immunostaining for ghrelin in the stroma, primordial follicles (PF) and the ovarian surface epithelium (OSE). (B) Ovarian section showing p... |
PMC1291400_F3_3928.jpg | What does this image primarily show? | Immunohistochemical and in situ localisation of ghrelin and GHSR-1a in sheep gonads. Photomicrographs of sheep ovarian and testicular sections. (A) Ovarian section showing positive immunostaining for ghrelin in the stroma, primordial follicles (PF) and the ovarian surface epithelium (OSE). (B) Ovarian section showing p... |
PMC1291404_F5_3930.jpg | What is the main focus of this visual representation? | In-vivo engraftment and viability controls. GFP signals were researched by confocal microscopy on lungs frozen sections. In a first step, GFP-labeled MSCs were directly injected in ex-vivo excised lungs in order to provide positive control (A, arrow) for confocal images interpretation whereas a non-injected freshly har... |
PMC1291404_F5_3931.jpg | What stands out most in this visual? | In-vivo engraftment and viability controls. GFP signals were researched by confocal microscopy on lungs frozen sections. In a first step, GFP-labeled MSCs were directly injected in ex-vivo excised lungs in order to provide positive control (A, arrow) for confocal images interpretation whereas a non-injected freshly har... |
PMC1297562_F4_3933.jpg | What can you see in this picture? | Immnunostaining for VEGF in synovial tissue in AIA rats. (a),(c), (e) AIA rats treated with deionized water and (b),(d) tetrathiomolybdate (TM). Immunohistochemical staining was performed with the Vecto Stain avidin–biotin peroxidase complex kit (Vector Laboratories, Burlingame, CA, USA). Synovial tissues sections were... |
PMC1297562_F4_3934.jpg | What is being portrayed in this visual content? | Immnunostaining for VEGF in synovial tissue in AIA rats. (a),(c), (e) AIA rats treated with deionized water and (b),(d) tetrathiomolybdate (TM). Immunohistochemical staining was performed with the Vecto Stain avidin–biotin peroxidase complex kit (Vector Laboratories, Burlingame, CA, USA). Synovial tissues sections were... |
PMC1297562_F4_3936.jpg | What can you see in this picture? | Immnunostaining for VEGF in synovial tissue in AIA rats. (a),(c), (e) AIA rats treated with deionized water and (b),(d) tetrathiomolybdate (TM). Immunohistochemical staining was performed with the Vecto Stain avidin–biotin peroxidase complex kit (Vector Laboratories, Burlingame, CA, USA). Synovial tissues sections were... |
PMC1297562_F4_3937.jpg | What does this image primarily show? | Immnunostaining for VEGF in synovial tissue in AIA rats. (a),(c), (e) AIA rats treated with deionized water and (b),(d) tetrathiomolybdate (TM). Immunohistochemical staining was performed with the Vecto Stain avidin–biotin peroxidase complex kit (Vector Laboratories, Burlingame, CA, USA). Synovial tissues sections were... |
PMC1297562_F4_3935.jpg | What object or scene is depicted here? | Immnunostaining for VEGF in synovial tissue in AIA rats. (a),(c), (e) AIA rats treated with deionized water and (b),(d) tetrathiomolybdate (TM). Immunohistochemical staining was performed with the Vecto Stain avidin–biotin peroxidase complex kit (Vector Laboratories, Burlingame, CA, USA). Synovial tissues sections were... |
PMC1297566_F3_3944.jpg | What is the central feature of this picture? | Detection of apoptotic cells and Fas/Fas ligand (FasL) protein expression in grafted rheumatoid arthritis (RA) synovium. The RA synovium in severe combined immunodeficiency (SCID) mice was harvested approximately two weeks after engraftment without or with three day treatment with 1011 particles of recombinant FasL ade... |
PMC1297566_F3_3938.jpg | What is the core subject represented in this visual? | Detection of apoptotic cells and Fas/Fas ligand (FasL) protein expression in grafted rheumatoid arthritis (RA) synovium. The RA synovium in severe combined immunodeficiency (SCID) mice was harvested approximately two weeks after engraftment without or with three day treatment with 1011 particles of recombinant FasL ade... |
PMC1297566_F3_3943.jpg | Can you identify the primary element in this image? | Detection of apoptotic cells and Fas/Fas ligand (FasL) protein expression in grafted rheumatoid arthritis (RA) synovium. The RA synovium in severe combined immunodeficiency (SCID) mice was harvested approximately two weeks after engraftment without or with three day treatment with 1011 particles of recombinant FasL ade... |
PMC1297566_F3_3940.jpg | What is shown in this image? | Detection of apoptotic cells and Fas/Fas ligand (FasL) protein expression in grafted rheumatoid arthritis (RA) synovium. The RA synovium in severe combined immunodeficiency (SCID) mice was harvested approximately two weeks after engraftment without or with three day treatment with 1011 particles of recombinant FasL ade... |
PMC1297566_F5_3949.jpg | What is the focal point of this photograph? | Reduction of the size and cell density of rheumatoid arthritis (RA) synovium in vivo by repeated Fas ligand (FasL) gene transfer. (a) RA synovium, 200 mg tissue per mouse, was grafted into the back of each severe combined immunodeficiency (SCID) mouse subcutaneously. Two weeks after engraftment, 1011 particles of recom... |
PMC1297566_F5_3947.jpg | What is shown in this image? | Reduction of the size and cell density of rheumatoid arthritis (RA) synovium in vivo by repeated Fas ligand (FasL) gene transfer. (a) RA synovium, 200 mg tissue per mouse, was grafted into the back of each severe combined immunodeficiency (SCID) mouse subcutaneously. Two weeks after engraftment, 1011 particles of recom... |
PMC1297566_F5_3948.jpg | What key item or scene is captured in this photo? | Reduction of the size and cell density of rheumatoid arthritis (RA) synovium in vivo by repeated Fas ligand (FasL) gene transfer. (a) RA synovium, 200 mg tissue per mouse, was grafted into the back of each severe combined immunodeficiency (SCID) mouse subcutaneously. Two weeks after engraftment, 1011 particles of recom... |
PMC1297566_F5_3950.jpg | What does this image primarily show? | Reduction of the size and cell density of rheumatoid arthritis (RA) synovium in vivo by repeated Fas ligand (FasL) gene transfer. (a) RA synovium, 200 mg tissue per mouse, was grafted into the back of each severe combined immunodeficiency (SCID) mouse subcutaneously. Two weeks after engraftment, 1011 particles of recom... |
PMC1297578_F2_3952.jpg | What is the central feature of this picture? | Evidence of PDB in two affected subjects from F01 family. (a) Bone deformity of the right forearm of family member II-3. Relatives described him as having suffered from multiple bone deformities and pain. (b) X-ray scan of the right tibia of family member III-3, with a typical flame-shaped lytic wedge (arrow). |
PMC1297578_F2_3951.jpg | Can you identify the primary element in this image? | Evidence of PDB in two affected subjects from F01 family. (a) Bone deformity of the right forearm of family member II-3. Relatives described him as having suffered from multiple bone deformities and pain. (b) X-ray scan of the right tibia of family member III-3, with a typical flame-shaped lytic wedge (arrow). |
PMC1297579_F2_3958.jpg | What is the focal point of this photograph? | Clinical and histological evaluation of arthritis. Clinical and histological evaluation demonstrates that arthritis induced with 200 μg glucose-6-phosphate isomerase (G6PI) in complete Freund's adjuvant (CFA) leads to chronic destructive arthritis in mice on the C3H background. (a) Healthy C3H.Q hind foot. (b) A C3H.Q ... |
PMC1297579_F2_3959.jpg | What's the most prominent thing you notice in this picture? | Clinical and histological evaluation of arthritis. Clinical and histological evaluation demonstrates that arthritis induced with 200 μg glucose-6-phosphate isomerase (G6PI) in complete Freund's adjuvant (CFA) leads to chronic destructive arthritis in mice on the C3H background. (a) Healthy C3H.Q hind foot. (b) A C3H.Q ... |
PMC1297579_F2_3960.jpg | What stands out most in this visual? | Clinical and histological evaluation of arthritis. Clinical and histological evaluation demonstrates that arthritis induced with 200 μg glucose-6-phosphate isomerase (G6PI) in complete Freund's adjuvant (CFA) leads to chronic destructive arthritis in mice on the C3H background. (a) Healthy C3H.Q hind foot. (b) A C3H.Q ... |
PMC1297579_F2_3957.jpg | What is the focal point of this photograph? | Clinical and histological evaluation of arthritis. Clinical and histological evaluation demonstrates that arthritis induced with 200 μg glucose-6-phosphate isomerase (G6PI) in complete Freund's adjuvant (CFA) leads to chronic destructive arthritis in mice on the C3H background. (a) Healthy C3H.Q hind foot. (b) A C3H.Q ... |
PMC1297579_F2_3954.jpg | What stands out most in this visual? | Clinical and histological evaluation of arthritis. Clinical and histological evaluation demonstrates that arthritis induced with 200 μg glucose-6-phosphate isomerase (G6PI) in complete Freund's adjuvant (CFA) leads to chronic destructive arthritis in mice on the C3H background. (a) Healthy C3H.Q hind foot. (b) A C3H.Q ... |
PMC1297579_F2_3953.jpg | What key item or scene is captured in this photo? | Clinical and histological evaluation of arthritis. Clinical and histological evaluation demonstrates that arthritis induced with 200 μg glucose-6-phosphate isomerase (G6PI) in complete Freund's adjuvant (CFA) leads to chronic destructive arthritis in mice on the C3H background. (a) Healthy C3H.Q hind foot. (b) A C3H.Q ... |
PMC1297584_F2_3963.jpg | What is being portrayed in this visual content? | Effect of DHMEQ on radiographic findings in collagen-induced arthritis in mice. (a) A representative radiograph of the left metatarsophalangeal (MTP) joints of a mouse treated with dehydroxymethylepoxyquinomicin (DHMEQ), which shows small bone erosions, and (b) that of a control mouse, which shows remarkable soft tissu... |
PMC1297593_F5_3966.jpg | What is the dominant medical problem in this image? | Localisation of α-enolase in synovial membranes. Immunohistochemistry of biopsy sections from patients with osteoarthritis (a) and rheumatoid arthritis (RA) (b) with the goat anti-α-enolase antibody showing expression of α-enolase (stained brown) in cells in the subsynovium of the patient with RA and in endothelial cel... |
PMC1297611_F2_3976.jpg | What is the main focus of this visual representation? | Representative CT scan of one animal at three different levels (apical, middle, basal). (a) Expiratory occlusion (10 cmH2O) before and after the recruitment maneuver. Lung volumes in this animal changed as follows: VHYP +1%, VNORM +15%, VPOOR +17%, VNON -30%, VGAS +11%. (b) Inspiratory occlusion at plateau pressure bef... |
PMC1297611_F2_3975.jpg | What is the principal component of this image? | Representative CT scan of one animal at three different levels (apical, middle, basal). (a) Expiratory occlusion (10 cmH2O) before and after the recruitment maneuver. Lung volumes in this animal changed as follows: VHYP +1%, VNORM +15%, VPOOR +17%, VNON -30%, VGAS +11%. (b) Inspiratory occlusion at plateau pressure bef... |
PMC1297611_F2_3977.jpg | What is the core subject represented in this visual? | Representative CT scan of one animal at three different levels (apical, middle, basal). (a) Expiratory occlusion (10 cmH2O) before and after the recruitment maneuver. Lung volumes in this animal changed as follows: VHYP +1%, VNORM +15%, VPOOR +17%, VNON -30%, VGAS +11%. (b) Inspiratory occlusion at plateau pressure bef... |
PMC1297611_F2_3974.jpg | What key item or scene is captured in this photo? | Representative CT scan of one animal at three different levels (apical, middle, basal). (a) Expiratory occlusion (10 cmH2O) before and after the recruitment maneuver. Lung volumes in this animal changed as follows: VHYP +1%, VNORM +15%, VPOOR +17%, VNON -30%, VGAS +11%. (b) Inspiratory occlusion at plateau pressure bef... |
PMC1297611_F3_3968.jpg | Describe the main subject of this image. | Distribution of differently aerated lung volumes. Individual curves for eight animals before (solid line) and after (dashed line) a recruitment maneuver. Multi-slice CT of the whole lung with characterization of lung parenchyma according to Hounsfield units at end-expiration. VHYP, volume of hyperinflated lung parenchy... |
PMC1298306_F1_3979.jpg | What stands out most in this visual? | SDF-1 Western blot. Recombinant murine SDF-1α (25 or 100 ng per lane) was run on a one-D gel, transferred to PVDF membrane and probed with the SDF-1 antibody used in the immunohistochemical assays. The western blot demonstrates that the SDF-1 antibody recognizes murine SDF-1α. |
PMC1298306_F3_3985.jpg | What key item or scene is captured in this photo? | Constitutive SDF-1 protein expression at P8. The left column shows SDF-1 antibody staining of P8 mouse brain (Cy3 – red). The middle column shows the corresponding nuclear labelling (bis-benzimide – blue) of the same sections. The right hand column shows the merged images. Panels A-C show the distribution of constituti... |
PMC1298306_F3_3983.jpg | What stands out most in this visual? | Constitutive SDF-1 protein expression at P8. The left column shows SDF-1 antibody staining of P8 mouse brain (Cy3 – red). The middle column shows the corresponding nuclear labelling (bis-benzimide – blue) of the same sections. The right hand column shows the merged images. Panels A-C show the distribution of constituti... |
PMC1298306_F3_3989.jpg | What's the most prominent thing you notice in this picture? | Constitutive SDF-1 protein expression at P8. The left column shows SDF-1 antibody staining of P8 mouse brain (Cy3 – red). The middle column shows the corresponding nuclear labelling (bis-benzimide – blue) of the same sections. The right hand column shows the merged images. Panels A-C show the distribution of constituti... |
PMC1298306_F3_3982.jpg | Describe the main subject of this image. | Constitutive SDF-1 protein expression at P8. The left column shows SDF-1 antibody staining of P8 mouse brain (Cy3 – red). The middle column shows the corresponding nuclear labelling (bis-benzimide – blue) of the same sections. The right hand column shows the merged images. Panels A-C show the distribution of constituti... |
PMC1298306_F3_3986.jpg | What is the main focus of this visual representation? | Constitutive SDF-1 protein expression at P8. The left column shows SDF-1 antibody staining of P8 mouse brain (Cy3 – red). The middle column shows the corresponding nuclear labelling (bis-benzimide – blue) of the same sections. The right hand column shows the merged images. Panels A-C show the distribution of constituti... |
PMC1298306_F3_3988.jpg | What is the dominant medical problem in this image? | Constitutive SDF-1 protein expression at P8. The left column shows SDF-1 antibody staining of P8 mouse brain (Cy3 – red). The middle column shows the corresponding nuclear labelling (bis-benzimide – blue) of the same sections. The right hand column shows the merged images. Panels A-C show the distribution of constituti... |
PMC1298306_F9_3990.jpg | What is the focal point of this photograph? | Astrocyte Expression of SDF-1. GFAP and SDF-1 dual labeling is demonstrated by confocal microscopy in P10 mice, three days post-HI. Panels A-C, from the striatum, show perivascular (arrowheads) astrocyte (GFAP – green) expression of SDF-1 (red). Panels D-F, from the hippocampus, show (arrowhead) similar co-labeling of ... |
PMC1298306_F9_3994.jpg | What is the principal component of this image? | Astrocyte Expression of SDF-1. GFAP and SDF-1 dual labeling is demonstrated by confocal microscopy in P10 mice, three days post-HI. Panels A-C, from the striatum, show perivascular (arrowheads) astrocyte (GFAP – green) expression of SDF-1 (red). Panels D-F, from the hippocampus, show (arrowhead) similar co-labeling of ... |
PMC1298306_F9_3995.jpg | What is the focal point of this photograph? | Astrocyte Expression of SDF-1. GFAP and SDF-1 dual labeling is demonstrated by confocal microscopy in P10 mice, three days post-HI. Panels A-C, from the striatum, show perivascular (arrowheads) astrocyte (GFAP – green) expression of SDF-1 (red). Panels D-F, from the hippocampus, show (arrowhead) similar co-labeling of ... |
PMC1298306_F9_3991.jpg | What does this image primarily show? | Astrocyte Expression of SDF-1. GFAP and SDF-1 dual labeling is demonstrated by confocal microscopy in P10 mice, three days post-HI. Panels A-C, from the striatum, show perivascular (arrowheads) astrocyte (GFAP – green) expression of SDF-1 (red). Panels D-F, from the hippocampus, show (arrowhead) similar co-labeling of ... |
PMC1298306_F9_3992.jpg | What is being portrayed in this visual content? | Astrocyte Expression of SDF-1. GFAP and SDF-1 dual labeling is demonstrated by confocal microscopy in P10 mice, three days post-HI. Panels A-C, from the striatum, show perivascular (arrowheads) astrocyte (GFAP – green) expression of SDF-1 (red). Panels D-F, from the hippocampus, show (arrowhead) similar co-labeling of ... |
PMC1298314_F2_3996.jpg | What object or scene is depicted here? | Overexpressed aurora B is incorporated into the nucleus after cell division. An NRK cell overexpressing aurora B-GFP was monitored by time-lapse microscopic imaging. Phase-contrast (a-c) and corresponding fluorescence images (a'-c') showed the dynamics of overexpressed aurora B-GFP during cytokinesis. Majority of auror... |
PMC1298314_F2_4000.jpg | What is the core subject represented in this visual? | Overexpressed aurora B is incorporated into the nucleus after cell division. An NRK cell overexpressing aurora B-GFP was monitored by time-lapse microscopic imaging. Phase-contrast (a-c) and corresponding fluorescence images (a'-c') showed the dynamics of overexpressed aurora B-GFP during cytokinesis. Majority of auror... |
PMC1298314_F2_4001.jpg | What is the central feature of this picture? | Overexpressed aurora B is incorporated into the nucleus after cell division. An NRK cell overexpressing aurora B-GFP was monitored by time-lapse microscopic imaging. Phase-contrast (a-c) and corresponding fluorescence images (a'-c') showed the dynamics of overexpressed aurora B-GFP during cytokinesis. Majority of auror... |
PMC1298314_F2_3997.jpg | What does this image primarily show? | Overexpressed aurora B is incorporated into the nucleus after cell division. An NRK cell overexpressing aurora B-GFP was monitored by time-lapse microscopic imaging. Phase-contrast (a-c) and corresponding fluorescence images (a'-c') showed the dynamics of overexpressed aurora B-GFP during cytokinesis. Majority of auror... |
PMC1298314_F3_4002.jpg | Describe the main subject of this image. | Overexpression of aurora B kinase does not phosphorylate histone H3 in interphase NRK cells. NRK cells overexpressing aurora B-GFP was stained with antibodies that specifically recognised histone H3 phosphorylated at Ser10 and then examined the expression of aurora B-GFP (a) and phosphorylation of histone H3 (c) by con... |
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