accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P15813 | CD1D_HUMAN | R3G1 | Homo | <M><G><C><L><L><F><L><L><L><W><A><L><L><Q><A><W><G><S><A><E><V><P><Q><R><L><F><P><L><R><C><L><Q><I><S><S><F><A><N><S><S><W><T><R><T><D><G><L><A><W><L><G><E><L><Q><T><H><S><W><S><N><D><S><D><T><V><R><S><L><K><P><W><S><Q><G><T><F><S><D><Q><Q><W><E><T><L><Q><H><I><F><R><V><Y><R><S><S><F><T><R><D><V><K><E><F><A><K><M><L><R... | Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<BOP> | P15813 |
A6NDV4 | TMM8B_HUMAN | Protein NGX6 | Homo | <M><N><M><P><Q><S><L><G><N><Q><P><L><P><P><E><P><P><S><L><G><T><P><A><E><G><P><G><T><T><S><P><P><E><H><C><W><P><V><R><P><T><L><R><N><E><L><D><T><F><S><V><H><F><Y><I><F><F><G><P><S><V><A><L><P><P><E><R><P><A><V><F><A><M><R><L><L><P><V><L><D><S><G><G><V><L><S><L><E><L><Q><L><N><A><S><S><V><R><Q><E><N><V><T><V><F><G><C><L... | May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion.<BOP> | A6NDV4 |
P54710 | ATNG_HUMAN | Sodium pump gamma chain | Homo | <M><T><G><L><S><M><D><G><G><G><S><P><K><G><D><V><D><P><F><Y><Y><D><Y><E><T><V><R><N><G><G><L><I><F><A><G><L><A><F><I><V><G><L><L><I><L><L><S><R><R><F><R><C><G><G><N><K><K><R><R><Q><I><N><E><D><E><P> | May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.<BOP> | P54710 |
Q6IE38 | ISK14_HUMAN | Serine protease inhibitor Kazal-type 14 | Homo | <M><A><K><S><F><P><V><F><S><L><L><S><F><I><L><I><H><L><V><L><S><S><V><S><G><P><R><H><W><W><P><P><R><G><I><I><K><V><K><C><P><Y><E><K><V><N><L><S><W><Y><N><G><T><V><N><P><C><P><G><L><Y><Q><P><I><C><G><T><N><F><I><T><Y><D><N><P><C><I><L><C><V><E><S><L><K><S><H><G><R><I><R><F><Y><H><D><G><K><C> | May be a serine protease inhibitor.<BOP> | Q6IE38 |
Q8N823 | ZN611_HUMAN | Zinc finger protein 611 | Homo | <M><L><R><E><E><A><A><Q><K><R><K><G><K><E><P><G><M><A><L><P><Q><G><R><L><T><F><R><D><V><A><I><E><F><S><L><A><E><W><K><C><L><N><P><S><Q><R><A><L><Y><R><E><V><M><L><E><N><Y><R><N><L><E><A><V><D><I><S><S><K><C><M><M><K><E><V><L><S><T><G><Q><G><N><T><E><V><I><H><T><G><T><L><Q><R><H><E><S><H><H><I><G><D><F><C><F><Q><E><I><E... | May be involved in transcriptional regulation.<BOP> | Q8N823 |
Q96HU1 | SGSM3_HUMAN | Rab-GTPase-activating protein-like protein | Homo | <M><S><G><S><H><T><P><A><C><G><P><F><S><A><L><T><P><S><I><W><P><Q><E><I><L><A><K><Y><T><Q><K><E><E><S><A><E><Q><P><E><F><Y><Y><D><E><F><G><F><R><V><Y><K><E><E><G><D><E><P><G><S><S><L><L><A><N><S><P><L><M><E><D><A><P><Q><R><L><R><W><Q><A><H><L><E><F><T><H><N><H><D><V><G><D><L><T><W><D><K><I><A><V><S><L><P><R><S><E><K><L... | May play a cooperative role in NF2-mediated growth suppression of cells.<BOP> | Q96HU1 |
Q9NUQ2 | PLCE_HUMAN | Lysophosphatidic acid acyltransferase epsilon | Homo | <M><L><L><S><L><V><L><H><T><Y><S><M><R><Y><L><L><P><S><V><V><L><L><G><T><A><P><T><Y><V><L><A><W><G><V><W><R><L><L><S><A><F><L><P><A><R><F><Y><Q><A><L><D><D><R><L><Y><C><V><Y><Q><S><M><V><L><F><F><F><E><N><Y><T><G><V><Q><I><L><L><Y><G><D><L><P><K><N><K><E><N><I><I><Y><L><A><N><H><Q><S><T><V><D><W><I><V><A><D><I><L><A><I... | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:... | Q9NUQ2 |
O14810 | CPLX1_HUMAN | Synaphin-2 | Homo | <M><E><F><V><M><K><Q><A><L><G><G><A><T><K><D><M><G><K><M><L><G><G><D><E><E><K><D><P><D><A><A><K><K><E><E><E><R><Q><E><A><L><R><Q><A><E><E><E><R><K><A><K><Y><A><K><M><E><A><E><R><E><A><V><R><Q><G><I><R><D><K><Y><G><I><K><K><K><E><E><R><E><A><E><A><Q><A><A><M><E><A><N><S><E><G><S><L><T><R><P><K><K><A><I><P><P><G><C><G><D... | Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles . Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from re... | O14810 |
P54840 | GYS2_HUMAN | Glycogen [starch] synthase, liver | Homo | <M><L><R><G><R><S><L><S><V><T><S><L><G><G><L><P><Q><W><E><V><E><E><L><P><V><E><E><L><L><L><F><E><V><A><W><E><V><T><N><K><V><G><G><I><Y><T><V><I><Q><T><K><A><K><T><T><A><D><E><W><G><E><N><Y><F><L><I><G><P><Y><F><E><H><N><M><K><T><Q><V><E><Q><C><E><P><V><N><D><A><V><R><R><A><V><D><A><M><N><K><H><G><C><Q><V><H><F><G><R><W... | Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.<BOP> | P54840 |
Q6ZTN6 | AN13D_HUMAN | Ankyrin repeat domain-containing protein 13D | Homo | <M><A><G><P><G><P><T><F><P><L><H><R><L><V><W><A><N><R><H><R><E><L><E><A><A><L><H><S><H><Q><H><D><I><E><Q><E><D><P><R><G><R><T><P><L><E><L><A><V><S><L><G><N><L><E><S><V><R><V><L><L><R><H><N><A><N><V><G><K><E><N><R><Q><G><W><A><V><L><Q><E><A><V><S><T><G><D><P><E><M><V><Q><L><V><L><Q><Y><R><D><Y><Q><R><A><T><Q><R><L><A><G... | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.<BOP> | Q6ZTN6 |
P50461 | CSRP3_HUMAN | Muscle LIM protein | Homo | <M><P><N><W><G><G><G><A><K><C><G><A><C><E><K><T><V><Y><H><A><E><E><I><Q><C><N><G><R><S><F><H><K><T><C><F><H><C><M><A><C><R><K><A><L><D><S><T><T><V><A><A><H><E><S><E><I><Y><C><K><V><C><Y><G><R><R><Y><G><P><K><G><I><G><Y><G><Q><G><A><G><C><L><S><T><D><T><G><E><H><L><G><L><Q><F><Q><Q><S><P><K><P><A><R><S><V><T><T><S><N><P... | May play a role in early sarcomere organization. Overexpression in myotubes negatively regulates myotube differentiation. By association with isoform 1 and thus changing the CSRP3 isoform 1:CFL2 stoichiometry is proposed to down-regulate CFL2-mediated F-actin depolymerization.<BOP> | P50461 |
Q9NS93 | TM7S3_HUMAN | Seven span transmembrane protein | Homo | <M><G><F><L><Q><L><L><V><V><A><V><L><A><S><E><H><R><V><A><G><A><A><E><V><F><G><N><S><S><E><G><L><I><E><F><S><V><G><K><F><R><Y><F><E><L><N><R><P><F><P><E><E><A><I><L><H><D><I><S><S><N><V><T><F><L><I><F><Q><I><H><S><Q><Y><Q><N><T><T><V><S><F><S><P><T><L><L><S><N><S><S><E><T><G><T><A><S><G><L><V><F><I><L><R><P><E><Q><S><T... | Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells . Is a downstream transcriptional target of p53/TP53, and acts as a pro-survival homeostatic factor that attenuates the development of cellular stress. Maintains prote... | Q9NS93 |
P48506 | GSH1_HUMAN | Gamma-glutamylcysteine synthetase | Homo | <M><G><L><L><S><Q><G><S><P><L><S><W><E><E><T><K><R><H><A><D><H><V><R><R><H><G><I><L><Q><F><L><H><I><Y><H><A><V><K><D><R><H><K><D><V><L><K><W><G><D><E><V><E><Y><M><L><V><S><F><D><H><E><N><K><K><V><R><L><V><L><S><G><E><K><V><L><E><T><L><Q><E><K><G><E><R><T><N><P><N><H><P><T><L><W><R><P><E><Y><G><S><Y><M><I><E><G><T><P><G... | Catalyzes the ATP-dependent ligation of L-glutamate and L-cysteine and participates in the first and rate-limiting step in glutathione biosynthesis.<BOP> | P48506 |
Q15126 | PMVK_HUMAN | Phosphomevalonate kinase | Homo | <M><A><P><L><G><G><A><P><R><L><V><L><L><F><S><G><K><R><K><S><G><K><D><F><V><T><E><A><L><Q><S><R><L><G><A><D><V><C><A><V><L><R><L><S><G><P><L><K><E><Q><Y><A><Q><E><H><G><L><N><F><Q><R><L><L><D><T><S><T><Y><K><E><A><F><R><K><D><M><I><R><W><G><E><E><K><R><Q><A><D><P><G><F><F><C><R><K><I><V><E><G><I><S><Q><P><I><W><L><V><S... | Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites.<BOP> | Q15126 |
P01876 | IGHA1_HUMAN | Ig alpha-1 chain C region TRO | Homo | <A><S><P><T><S><P><K><V><F><P><L><S><L><C><S><T><Q><P><D><G><N><V><V><I><A><C><L><V><Q><G><F><F><P><Q><E><P><L><S><V><T><W><S><E><S><G><Q><G><V><T><A><R><N><F><P><P><S><Q><D><A><S><G><D><L><Y><T><T><S><S><Q><L><T><L><P><A><T><Q><C><L><A><G><K><S><V><T><C><H><V><K><H><Y><T><N><P><S><Q><D><V><T><V><P><C><P><V><P><S><T><P... | Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the cl... | P01876 |
Q9HBI6 | CP4FB_HUMAN | Phylloquinone omega-hydroxylase CYP4F11 | Homo | <M><P><Q><L><S><L><S><W><L><G><L><G><P><V><A><A><S><P><W><L><L><L><L><L><V><G><G><S><W><L><L><A><R><V><L><A><W><T><Y><T><F><Y><D><N><C><R><R><L><Q><C><F><P><Q><P><P><K><Q><N><W><F><W><G><H><Q><G><L><V><T><P><T><E><E><G><M><K><T><L><T><Q><L><V><T><T><Y><P><Q><G><F><K><L><W><L><G><P><T><F><P><L><L><I><L><C><H><P><D><I><I... | A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids and their oxygenated derivatives (oxylipins) . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided ... | Q9HBI6 |
Q16581 | C3AR_HUMAN | C3a anaphylatoxin chemotactic receptor | Homo | <M><A><S><F><S><A><E><T><N><S><T><D><L><L><S><Q><P><W><N><E><P><P><V><I><L><S><M><V><I><L><S><L><T><F><L><L><G><L><P><G><N><G><L><V><L><W><V><A><G><L><K><M><Q><R><T><V><N><T><I><W><F><L><H><L><T><L><A><D><L><L><C><C><L><S><L><P><F><S><L><A><H><L><A><L><Q><G><Q><W><P><Y><G><R><F><L><C><K><L><I><P><S><I><I><V><L><N><M><F... | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.<BOP> | Q16581 |
P23490 | LORI_HUMAN | Loricrin | Homo | <M><S><Y><Q><K><K><Q><P><T><P><Q><P><P><V><D><C><V><K><T><S><G><G><G><G><G><G><G><G><S><G><G><G><G><C><G><F><F><G><G><G><G><S><G><G><G><S><S><G><S><G><C><G><Y><S><G><G><G><G><Y><S><G><G><G><C><G><G><G><S><S><G><G><G><G><G><G><G><I><G><G><C><G><G><G><S><G><G><S><V><K><Y><S><G><G><G><G><S><S><G><G><G><S><G><C><F><S><S><G... | Major keratinocyte cell envelope protein.<BOP> | P23490 |
P49137 | MAPK2_HUMAN | MAP kinase-activated protein kinase 2 | Homo | <M><L><S><N><S><Q><G><Q><S><P><P><V><P><F><P><A><P><A><P><P><P><Q><P><P><T><P><A><L><P><H><P><P><A><Q><P><P><P><P><P><P><Q><Q><F><P><Q><F><H><V><K><S><G><L><Q><I><K><K><N><A><I><I><D><D><Y><K><V><T><S><Q><V><L><G><L><G><I><N><G><K><V><L><Q><I><F><N><K><R><T><Q><E><K><F><A><L><K><M><L><Q><D><C><P><K><A><R><R><E><V><E><L... | Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MA... | P49137 |
Q6Y1H2 | HACD2_HUMAN | Protein-tyrosine phosphatase-like member B | Homo | <M><A><A><V><A><A><T><A><A><A><K><G><N><G><G><G><G><G><R><A><G><A><G><D><A><S><G><T><R><K><K><K><G><P><G><P><L><A><T><A><Y><L><V><I><Y><N><V><V><M><T><A><G><W><L><V><I><A><V><G><L><V><R><A><Y><L><A><K><G><S><Y><H><S><L><Y><Y><S><I><E><K><P><L><K><F><F><Q><T><G><A><L><L><E><I><L><H><C><A><I><G><I><V><P><S><S><V><V><L><T... | Catalyzes the third of the very long-chain fatty acids (VLCFA) elongation four-step cycle (condensation, reduction, dehydration, and reduction). This endoplasmic reticulum-elongation process is characterized by the addition of two carbons to the lipid chain through each cycle. This enzyme catalyzes the dehydration of t... | Q6Y1H2 |
A0A0C4DH43 | HV70D_HUMAN | Immunoglobulin heavy variable 2-70D | Homo | <M><D><I><L><C><S><T><L><L><L><L><T><V><P><S><W><V><L><S><Q><V><T><L><K><E><S><G><P><A><L><V><K><P><T><Q><T><L><T><L><T><C><T><F><S><G><F><S><L><S><T><S><G><M><R><V><S><W><I><R><Q><P><P><G><K><A><L><E><W><L><A><R><I><D><W><D><D><D><K><F><Y><S><T><S><L><K><T><R><L><T><I><S><K><D><T><S><K><N><Q><V><V><L><T><M><T><N><M><D... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0C4DH43 |
Q9H1J1 | REN3A_HUMAN | Up-frameshift suppressor 3 homolog A | Homo | <M><R><S><E><K><E><G><A><G><G><L><R><A><A><V><A><A><R><G><P><S><G><R><E><K><L><S><A><L><E><V><Q><F><H><R><D><S><Q><Q><Q><E><A><E><T><P><P><T><S><S><S><G><C><G><G><G><A><G><K><P><R><E><E><K><R><T><A><L><S><K><V><V><I><R><R><L><P><P><G><L><T><K><E><Q><L><E><E><Q><L><R><P><L><P><A><H><D><Y><F><E><F><F><A><A><D><L><S><L><Y... | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surv... | Q9H1J1 |
A6NFA1 | TIKI2_HUMAN | TRAB domain-containing protein 2B | Homo | <M><H><A><A><L><A><G><P><L><L><A><A><L><L><A><T><A><R><A><R><P><Q><P><P><D><G><G><Q><C><R><P><P><G><S><Q><R><D><L><N><S><F><L><W><T><I><R><R><D><P><P><A><Y><L><F><G><T><I><H><V><P><Y><T><R><V><W><D><F><I><P><D><N><S><K><A><A><F><Q><A><S><T><R><V><Y><F><E><L><D><L><T><D><P><Y><T><I><S><A><L><A><S><C><Q><L><L><P><H><G><E... | Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not ... | A6NFA1 |
P49146 | NPY2R_HUMAN | NPY-Y2 receptor | Homo | <M><G><P><I><G><A><E><A><D><E><N><Q><T><V><E><E><M><K><V><E><Q><Y><G><P><Q><T><T><P><R><G><E><L><V><P><D><P><E><P><E><L><I><D><S><T><K><L><I><E><V><Q><V><V><L><I><L><A><Y><C><S><I><I><L><L><G><V><I><G><N><S><L><V><I><H><V><V><I><K><F><K><S><M><R><T><V><T><N><F><F><I><A><N><L><A><V><A><D><L><L><V><N><T><L><C><L><P><F><T... | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.<BOP> | P49146 |
Q9NZV7 | ZIM2_HUMAN | Zinc finger protein 656 | Homo | <M><Y><Q><P><E><D><D><N><N><S><D><V><T><S><D><D><D><M><T><R><N><R><R><E><S><S><P><P><H><S><V><H><S><F><S><G><D><R><D><W><D><R><R><G><R><S><R><D><M><E><P><R><D><R><W><S><H><T><R><N><P><R><S><R><M><P><P><R><D><L><S><L><P><V><V><A><K><T><S><F><E><M><D><R><E><D><D><R><D><S><R><A><Y><E><S><R><S><Q><D><A><E><S><Y><Q><N><V><V... | May be involved in transcriptional regulation.<BOP> | Q9NZV7 |
A0A0K0K1A3 | TVBJ1_HUMAN | T cell receptor beta variable 10-1 | Homo | <M><G><T><R><L><F><F><Y><V><A><L><C><L><L><W><A><G><H><R><D><A><E><I><T><Q><S><P><R><H><K><I><T><E><T><G><R><Q><V><T><L><A><C><H><Q><T><W><N><H><N><N><M><F><W><Y><R><Q><D><L><G><H><G><L><R><L><I><H><Y><S><Y><G><V><H><D><T><N><K><G><E><V><S><D><G><Y><S><V><S><R><S><N><T><E><D><L><P><L><T><L><E><S><A><A><S><S><Q><T><S><V... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A0K0K1A3 |
Q9BYQ8 | KRA49_HUMAN | Ultrahigh sulfur keratin-associated protein 4.9 | Homo | <M><V><S><S><C><C><G><S><V><C><S><D><Q><G><C><G><Q><D><L><C><Q><E><T><C><C><R><P><S><C><C><E><T><T><C><C><R><T><T><C><C><R><P><S><C><C><V><S><S><C><C><R><P><Q><C><C><Q><S><V><C><C><Q><P><T><C><S><R><P><S><C><C><Q><T><T><C><C><R><T><T><C><Y><R><P><S><C><C><V><S><S><C><C><R><P><Q><C><C><Q><P><A><C><C><Q><P><T><C><C><R><P... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q9BYQ8 |
Q6ZSS3 | ZN621_HUMAN | Zinc finger protein 621 | Homo | <M><L><Q><T><T><W><P><Q><E><S><V><T><F><E><D><V><A><V><Y><F><T><Q><N><Q><W><A><S><L><D><P><A><Q><R><A><L><Y><G><E><V><M><L><E><N><Y><A><N><V><A><S><L><V><A><F><P><F><P><K><P><A><L><I><S><H><L><E><R><G><E><A><P><W><G><P><D><P><W><D><T><E><I><L><R><G><I><S><Q><G><G><E><S><W><I><K><N><E><G><L><V><I><K><Q><E><A><S><E><E><T... | May be involved in transcriptional regulation.<BOP> | Q6ZSS3 |
Q9HB55 | CP343_HUMAN | Cytochrome P450 3A43 | Homo | <M><D><L><I><P><N><F><A><M><E><T><W><V><L><V><A><T><S><L><V><L><L><Y><I><Y><G><T><H><S><H><K><L><F><K><K><L><G><I><P><G><P><T><P><L><P><F><L><G><T><I><L><F><Y><L><R><G><L><W><N><F><D><R><E><C><N><E><K><Y><G><E><M><W><G><L><Y><E><G><Q><Q><P><M><L><V><I><M><D><P><D><M><I><K><T><V><L><V><K><E><C><Y><S><V><F><T><N><Q><M><P... | Exhibits low testosterone 6-beta-hydroxylase activity.<BOP> | Q9HB55 |
Q8NGJ7 | O51A2_HUMAN | Olfactory receptor 51A2 | Homo | <M><S><I><I><N><T><S><Y><V><E><I><T><T><F><F><L><V><G><M><P><G><L><E><Y><A><H><I><W><I><S><I><P><I><C><S><M><Y><L><I><A><I><L><G><N><G><T><I><L><F><I><I><K><T><E><P><S><L><H><G><P><M><Y><Y><F><L><S><M><L><A><M><S><D><L><G><L><S><L><S><S><L><P><T><V><L><S><I><F><L><F><N><A><P><E><T><S><S><S><A><C><F><A><Q><E><F><F><I><H... | Odorant receptor.<BOP> | Q8NGJ7 |
Q9H8H3 | MET7A_HUMAN | Protein AAM-B | Homo | <M><E><L><T><I><F><I><L><R><L><A><I><Y><I><L><T><F><P><L><Y><L><L><N><F><L><G><L><W><S><W><I><C><K><K><W><F><P><Y><F><L><V><R><F><T><V><I><Y><N><E><Q><M><A><S><K><K><R><E><L><F><S><N><L><Q><E><F><A><G><P><S><G><K><L><S><L><L><E><V><G><C><G><T><G><A><N><F><K><F><Y><P><P><G><C><R><V><T><C><I><D><P><N><P><N><F><E><K><F><L... | (Microbial infection) May be involved in the assembly and release stages of hepatitis C virus (HCV) life cycle and thus play a crucial role in HCV propagation.<BOP> | Q9H8H3 |
P63122 | VPK8_HUMAN | Proteinase | Homo | <W><A><S><Q><V><S><E><N><R><P><V><C><K><A><I><I><Q><G><K><Q><F><E><G><L><V><D><T><G><A><D><V><S><I><I><A><L><N><Q><W><P><K><N><W><P><K><Q><K><A><V><I><G><L><V><G><I><G><T><A><S><E><V><Y><Q><S><M><E><I><L><H><C><L><G><P><D><N><Q><E><S><T><V><Q><P><M><I><T><S><I><P><L><N><L><W><G><R><D><L><L><Q><Q><W><G><A><E><I><T><M><P... | Retroviral proteases have roles in the processing of the primary translation products and the maturation of the viral particle. Endogenous Pro proteins may have kept, lost or modified their original function during evolution.<BOP> | P63122 |
P28325 | CYTD_HUMAN | Cystatin-5 | Homo | <M><M><W><P><M><H><T><P><L><L><L><L><T><A><L><M><V><A><V><A><G><S><A><S><A><Q><S><R><T><L><A><G><G><I><H><A><T><D><L><N><D><K><S><V><Q><C><A><L><D><F><A><I><S><E><Y><N><K><V><I><N><K><D><E><Y><Y><S><R><P><L><Q><V><M><A><A><Y><Q><Q><I><V><G><G><V><N><Y><Y><F><N><V><K><F><G><R><T><T><C><T><K><S><Q><P><N><L><D><N><C><P><F... | Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B.<BOP> | P28325 |
A8MZ59 | LEUTX_HUMAN | Paired-like homeobox transcription factor LEUTX | Homo | <M><F><E><G><P><R><R><Y><R><R><P><R><T><R><F><L><S><K><Q><L><T><A><L><R><E><L><L><E><K><T><M><H><P><S><L><A><T><M><G><K><L><A><S><K><L><Q><L><D><L><S><V><V><K><I><W><F><K><N><Q><R><A><K><W><K><R><Q><Q><R><Q><Q><M><Q><T><R><P><S><L><G><P><A><N><Q><T><T><S><V><K><K><E><E><T><P><S><A><I><T><T><A><N><I><R><P><V><S><P><G><I... | Inactive transcriptional activity.<BOP> | A8MZ59 |
P37108 | SRP14_HUMAN | 18 kDa Alu RNA-binding protein | Homo | <M><V><L><L><E><S><E><Q><F><L><T><E><L><T><R><L><F><Q><K><C><R><T><S><G><S><V><Y><I><T><L><K><K><Y><D><G><R><T><K><P><I><P><K><K><G><T><V><E><G><F><E><P><A><D><N><K><C><L><L><R><A><T><D><G><K><K><K><I><S><T><V><V><S><S><K><E><V><N><K><F><Q><M><A><Y><S><N><L><L><R><A><N><M><D><G><L><K><K><R><D><K><K><N><K><T><K><K><T><K... | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) . SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP . The co... | P37108 |
Q9Y251 | HPSE_HUMAN | Heparanase 50 kDa subunit | Homo | <M><L><L><R><S><K><P><A><L><P><P><P><L><M><L><L><L><L><G><P><L><G><P><L><S><P><G><A><L><P><R><P><A><Q><A><Q><D><V><V><D><L><D><F><F><T><Q><E><P><L><H><L><V><S><P><S><F><L><S><V><T><I><D><A><N><L><A><T><D><P><R><F><L><I><L><L><G><S><P><K><L><R><T><L><A><R><G><L><S><P><A><Y><L><R><F><G><G><T><K><T><D><F><L><I><F><D><P><K... | Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or... | Q9Y251 |
Q8NGF6 | O10W1_HUMAN | Olfactory receptor OR11-236 | Homo | <M><E><F><V><F><L><A><Y><P><S><C><P><E><L><H><I><L><S><F><L><G><V><S><L><V><Y><G><L><I><I><T><G><N><I><L><I><V><V><S><I><H><T><E><T><C><L><C><T><S><M><Y><Y><F><L><G><S><L><S><G><I><E><I><C><Y><T><A><V><V><V><P><H><I><L><A><N><T><L><Q><S><E><K><T><I><T><L><L><G><C><A><T><Q><M><A><F><F><I><A><L><G><S><A><D><C><F><L><L><A... | Odorant receptor.<BOP> | Q8NGF6 |
Q93096 | TP4A1_HUMAN | Protein-tyrosine phosphatase of regenerating liver 1 | Homo | <M><A><R><M><N><R><P><A><P><V><E><V><T><Y><K><N><M><R><F><L><I><T><H><N><P><T><N><A><T><L><N><K><F><I><E><E><L><K><K><Y><G><V><T><T><I><V><R><V><C><E><A><T><Y><D><T><T><L><V><E><K><E><G><I><H><V><L><D><W><P><F><D><D><G><A><P><P><S><N><Q><I><V><D><D><W><L><S><L><V><K><I><K><F><R><E><E><P><G><C><C><I><A><V><H><C><V><A><G... | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.<BOP> | Q93096 |
P47944 | MT4_HUMAN | Metallothionein-IV | Homo | <M><D><P><R><E><C><V><C><M><S><G><G><I><C><M><C><G><D><N><C><K><C><T><T><C><N><C><K><T><Y><W><K><S><C><C><P><C><C><P><P><G><C><A><K><C><A><R><G><C><I><C><K><G><G><S><D><K><C><S><C><C><P> | Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.<BOP> | P47944 |
P36404 | ARL2_HUMAN | ADP-ribosylation factor-like protein 2 | Homo | <M><G><L><L><T><I><L><K><K><M><K><Q><K><E><R><E><L><R><L><L><M><L><G><L><D><N><A><G><K><T><T><I><L><K><K><F><N><G><E><D><I><D><T><I><S><P><T><L><G><F><N><I><K><T><L><E><H><R><G><F><K><L><N><I><W><D><V><G><G><Q><K><S><L><R><S><Y><W><R><N><Y><F><E><S><T><D><G><L><I><W><V><V><D><S><A><D><R><Q><R><M><Q><D><C><Q><R><E><L><Q... | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subun... | P36404 |
P35452 | HXD12_HUMAN | Homeobox protein Hox-4H | Homo | <M><C><E><R><S><L><Y><R><A><G><Y><V><G><S><L><L><N><L><Q><S><P><D><S><F><Y><F><S><N><L><R><P><N><G><G><Q><L><A><A><L><P><P><I><S><Y><P><R><G><A><L><P><W><A><A><T><P><A><S><C><A><P><A><Q><P><A><G><A><T><A><F><G><G><F><S><Q><P><Y><L><A><G><S><G><P><L><G><L><Q><P><P><T><A><K><D><G><P><E><E><Q><A><K><F><Y><A><P><E><A><A><A... | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP> | P35452 |
Q6XZB0 | LIPI_HUMAN | Membrane-associated phosphatidic acid-selective phospholipase A1-beta | Homo | <M><R><V><Y><I><F><L><C><L><M><C><W><V><R><S><D><N><K><R><P><C><L><E><F><S><Q><L><S><V><K><D><S><F><R><D><L><F><I><P><R><I><E><T><I><L><M><M><Y><T><R><N><N><L><N><C><A><E><P><L><F><E><Q><N><N><S><L><N><V><N><F><N><T><Q><K><K><T><V><W><L><I><H><G><Y><R><P><V><G><S><I><P><L><W><L><Q><N><F><V><R><I><L><L><N><E><E><D><M><N... | Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).<BOP> | Q6XZB0 |
A0A0A6YYD4 | TVB13_HUMAN | T cell receptor beta variable 13 | Homo | <M><L><S><P><D><L><P><D><S><A><W><N><T><R><L><L><C><R><V><M><L><C><L><L><G><A><G><S><V><A><A><G><V><I><Q><S><P><R><H><L><I><K><E><K><R><E><T><A><T><L><K><C><Y><P><I><P><R><H><D><T><V><Y><W><Y><Q><Q><G><P><G><Q><D><P><Q><F><L><I><S><F><Y><E><K><M><Q><S><D><K><G><S><I><P><D><R><F><S><A><Q><Q><F><S><D><Y><H><S><E><L><N><M... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A0A6YYD4 |
Q15800 | MSMO1_HUMAN | Sterol-C4-methyl oxidase | Homo | <M><A><T><N><E><S><V><S><I><F><S><S><A><S><L><A><V><E><Y><V><D><S><L><L><P><E><N><P><L><Q><E><P><F><K><N><A><W><N><Y><M><L><N><N><Y><T><K><F><Q><I><A><T><W><G><S><L><I><V><H><E><A><L><Y><F><L><F><C><L><P><G><F><L><F><Q><F><I><P><Y><M><K><K><Y><K><I><Q><K><D><K><P><E><T><W><E><N><Q><W><K><C><F><K><V><L><L><F><N><H><F><C... | Catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, which can be subsequently metabolized to cholesterol . Also involved in drug metabolism, as it can metabolize eldecalcitol (ED-71 or 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol), a second-g... | Q15800 |
P49758 | RGS6_HUMAN | S914 | Homo | <M><A><Q><G><S><G><D><Q><R><A><V><G><V><A><D><P><E><E><S><S><P><N><M><I><V><Y><C><K><I><E><D><I><I><T><K><M><Q><D><D><K><T><G><G><V><P><I><R><T><V><K><S><F><L><S><K><I><P><S><V><V><T><G><T><D><I><V><Q><W><L><M><K><N><L><S><I><E><D><P><V><E><A><I><H><L><G><S><L><I><A><A><Q><G><Y><I><F><P><I><S><D><H><V><L><T><M><K><D><D... | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity .<BOP> | P49758 |
Q9UNS2 | CSN3_HUMAN | JAB1-containing signalosome subunit 3 | Homo | <M><A><S><A><L><E><Q><F><V><N><S><V><R><Q><L><S><A><Q><G><Q><M><T><Q><L><C><E><L><I><N><K><S><G><E><L><L><A><K><N><L><S><H><L><D><T><V><L><G><A><L><D><V><Q><E><H><S><L><G><V><L><A><V><L><F><V><K><F><S><M><P><S><V><P><D><F><E><T><L><F><S><Q><V><Q><L><F><I><S><T><C><N><G><E><H><I><R><Y><A><T><D><T><F><A><G><L><C><H><Q><L... | Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl lig... | Q9UNS2 |
Q92737 | RSLAA_HUMAN | Ras-related protein on chromosome 22 | Homo | <M><G><G><S><L><R><V><A><V><L><G><A><P><G><V><G><K><T><A><I><I><R><Q><F><L><F><G><D><Y><P><E><R><H><R><P><T><D><G><P><R><L><Y><R><P><A><V><L><L><D><G><A><V><Y><D><L><S><I><R><D><G><D><V><A><G><P><G><S><S><P><G><G><P><E><E><W><P><D><A><K><D><W><S><L><Q><D><T><D><A><F><V><L><V><Y><D><I><C><S><P><D><S><F><D><Y><V><K><A><L... | Potent inhibitor of cellular proliferation.<BOP> | Q92737 |
Q8NH72 | OR4C6_HUMAN | Olfactory receptor OR11-138 | Homo | <M><E><N><Q><N><N><V><T><E><F><I><L><L><G><L><T><E><N><L><E><L><W><K><I><F><S><A><V><F><L><V><M><Y><V><A><T><V><L><E><N><L><L><I><V><V><T><I><I><T><S><Q><S><L><R><S><P><M><Y><F><F><L><T><F><L><S><L><L><D><V><M><F><S><S><V><V><A><P><K><V><I><V><D><T><L><S><K><S><T><T><I><S><L><K><G><C><L><T><Q><L><F><V><E><H><F><F><G><G... | Odorant receptor.<BOP> | Q8NH72 |
Q969H0 | FBXW7_HUMAN | hCdc4 | Homo | <M><N><Q><E><L><L><S><V><G><S><K><R><R><R><T><G><G><S><L><R><G><N><P><S><S><S><Q><V><D><E><E><Q><M><N><R><V><V><E><E><E><Q><Q><Q><Q><L><R><Q><Q><E><E><E><H><T><A><R><N><G><E><V><V><G><V><E><P><R><P><G><G><Q><N><D><S><Q><Q><G><Q><L><E><E><N><N><N><R><F><I><S><V><D><E><D><S><S><G><N><Q><E><E><Q><E><E><D><E><E><H><A><G><E... | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter brings them to the SCF compl... | Q969H0 |
O75949 | NALF2_HUMAN | Transmembrane protein FAM155B | Homo | <M><F><R><G><A><W><M><W><P><G><K><D><A><A><A><L><T><I><C><C><C><C><C><C><W><A><P><R><P><S><D><K><P><C><A><D><S><E><R><A><Q><R><W><R><L><S><L><A><S><L><L><F><F><T><V><L><L><A><D><H><L><W><L><C><A><G><A><R><P><R><A><R><E><L><S><S><A><M><R><P><P><W><G><A><G><R><E><R><Q><P><V><P><P><R><A><V><L><P><L><P><P><P><P><P><G><E><P... | Probable component of the NALCN channel complex, a channel that regulates the resting membrane potential and controls neuronal excitability.<BOP> | O75949 |
P61221 | ABCE1_HUMAN | Ribonuclease 4 inhibitor | Homo | <M><A><D><K><L><T><R><I><A><I><V><N><H><D><K><C><K><P><K><K><C><R><Q><E><C><K><K><S><C><P><V><V><R><M><G><K><L><C><I><E><V><T><P><Q><S><K><I><A><W><I><S><E><T><L><C><I><G><C><G><I><C><I><K><K><C><P><F><G><A><L><S><I><V><N><L><P><S><N><L><E><K><E><T><T><H><R><Y><C><A><N><A><F><K><L><H><R><L><P><I><P><R><P><G><E><V><L><G... | (Microbial infection) Plays a role in the down-regulation of the 2-5A/RNASEL pathway during encephalomyocarditis virus (EMCV) and HIV-1 infections.<BOP> | P61221 |
Q5VZV1 | MT21C_HUMAN | Methyltransferase-like protein 21C | Homo | <M><D><V><C><L><S><S><A><Q><Q><P><G><R><R><G><E><G><L><S><S><P><G><G><W><L><E><A><E><K><K><G><A><P><Q><K><D><S><T><G><G><V><L><E><E><S><N><K><I><E><P><S><L><H><S><L><Q><K><F><V><P><T><D><Y><A><S><Y><T><Q><E><H><Y><R><F><A><G><K><E><I><V><I><Q><E><S><I><E><S><Y><G><A><V><V><W><P><G><A><M><A><L><C><Q><Y><L><E><E><H><A><E... | Protein-lysine methyltransferase.<BOP> | Q5VZV1 |
Q13112 | CAF1B_HUMAN | M-phase phosphoprotein 7 | Homo | <M><K><V><I><T><C><E><I><A><W><H><N><K><E><P><V><Y><S><L><D><F><Q><H><G><T><A><G><R><I><H><R><L><A><S><A><G><V><D><T><N><V><R><I><W><K><V><E><K><G><P><D><G><K><A><I><V><E><F><L><S><N><L><A><R><H><T><K><A><V><N><V><V><R><F><S><P><T><G><E><I><L><A><S><G><G><D><D><A><V><I><L><L><W><K><V><N><D><N><K><E><P><E><Q><I><A><F><Q... | Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromat... | Q13112 |
Q9UK28 | TM59L_HUMAN | Brain-specific membrane-anchored protein | Homo | <M><A><A><V><A><L><M><P><P><P><L><L><L><L><L><L><L><A><S><P><P><A><A><S><A><P><S><A><R><D><P><F><A><P><Q><L><G><D><T><Q><N><C><Q><L><R><C><R><D><R><D><L><G><P><Q><P><S><Q><A><G><L><E><G><A><S><E><S><P><Y><D><R><A><V><L><I><S><A><C><E><R><G><C><R><L><F><S><I><C><R><F><V><A><R><S><S><K><P><N><A><T><Q><T><E><C><E><A><A><C... | Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding.<BOP> | Q9UK28 |
Q8NGJ9 | O51T1_HUMAN | Olfactory receptor OR11-26 | Homo | <M><A><I><F><N><N><T><T><S><S><S><S><N><F><L><L><T><A><F><P><G><L><E><C><A><H><V><W><I><S><I><P><V><C><C><L><Y><T><I><A><L><L><G><N><S><M><I><F><L><V><I><I><T><K><R><R><L><H><K><P><M><Y><Y><F><L><S><M><L><A><A><V><D><L><C><L><T><I><T><T><L><P><T><V><L><G><V><L><W><F><H><A><R><E><I><S><F><K><A><C><F><I><Q><M><F><F><V><H... | Odorant receptor.<BOP> | Q8NGJ9 |
P14621 | ACYP2_HUMAN | Acylphosphate phosphohydrolase 2 | Homo | <M><S><T><A><Q><S><L><K><S><V><D><Y><E><V><F><G><R><V><Q><G><V><C><F><R><M><Y><T><E><D><E><A><R><K><I><G><V><V><G><W><V><K><N><T><S><K><G><T><V><T><G><Q><V><Q><G><P><E><D><K><V><N><S><M><K><S><W><L><S><K><V><G><S><P><S><S><R><I><D><R><T><N><F><S><N><E><K><T><I><S><K><L><E><Y><S><N><F><S><I><R><Y> | Its physiological role is not yet clear.<BOP> | P14621 |
Q9P2W3 | GBG13_HUMAN | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | Homo | <M><E><E><W><D><V><P><Q><M><K><K><E><V><E><S><L><K><Y><Q><L><A><F><Q><R><E><M><A><S><K><T><I><P><E><L><L><K><W><I><E><D><G><I><P><K><D><P><F><L><N><P><D><L><M><K><N><N><P><W><V><E><K><G><K><C><T><I><L> | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<BOP> | Q9P2W3 |
Q96K21 | ANCHR_HUMAN | Zinc finger FYVE domain-containing protein 19 | Homo | <M><N><Y><D><S><Q><Q><P><P><L><P><P><L><P><Y><A><G><C><R><R><A><S><G><F><P><A><L><G><R><G><G><T><V><P><V><G><V><W><G><G><A><G><Q><G><R><E><G><R><S><W><G><E><G><P><R><G><P><G><L><G><R><R><D><L><S><S><A><D><P><A><V><L><G><A><T><M><E><S><R><C><Y><G><C><A><V><K><F><T><L><F><K><K><E><Y><G><C><K><N><C><G><R><A><F><C><S><G><C... | Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at ... | Q96K21 |
Q96RQ1 | ERGI2_HUMAN | Endoplasmic reticulum-Golgi intermediate compartment protein 2 | Homo | <M><R><R><L><N><R><K><K><T><L><S><L><V><K><E><L><D><A><F><P><K><V><P><E><S><Y><V><E><T><S><A><S><G><G><T><V><S><L><I><A><F><T><T><M><A><L><L><T><I><M><E><F><S><V><Y><Q><D><T><W><M><K><Y><E><Y><E><V><D><K><D><F><S><S><K><L><R><I><N><I><D><I><T><V><A><M><K><C><Q><Y><V><G><A><D><V><L><D><L><A><E><T><M><V><A><S><A><D><G><L... | Possible role in transport between endoplasmic reticulum and Golgi.<BOP> | Q96RQ1 |
Q5VUJ9 | DRC8_HUMAN | EF-hand calcium-binding domain-containing protein 2 | Homo | <M><L><G><P><G><Q><V><R><L><R><P><R><V><W><R><D><K><A><G><G><R><V><A><D><G><A><S><G><L><P><P><A><R><G><S><W><R><E><T><G><T><G><R><A><L><G><A><S><S><P><P><R><P><A><Q><G><S><S><S><P><G><I><Q><S><G><P><S><S><R><P><G><S><P><R><G><A><E><Q><A><G><T><P><R><P><R><L><S><L><G><I><S><Q><A><T><G><S><A><A><R><W><R><T><R><R><T><G><K... | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.<BOP> | Q5VUJ9 |
Q9HBV1 | POPD3_HUMAN | Popeye domain-containing protein 3 | Homo | <M><E><R><N><S><S><L><W><K><N><L><I><D><E><H><P><V><C><T><T><W><K><Q><E><A><E><G><A><I><Y><H><L><A><S><I><L><F><V><V><G><F><M><G><G><S><G><F><F><G><L><L><Y><V><F><S><L><L><G><L><G><F><L><C><S><A><V><W><A><W><V><D><V><C><A><A><D><I><F><S><W><N><F><V><L><F><V><I><C><F><M><Q><F><V><H><I><A><Y><Q><V><R><S><I><T><F><A><R><E... | May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding. May play a role in the regulation of KCNK2/TREK-1-mediated current amplitude .<BOP> | Q9HBV1 |
P01215 | GLHA_HUMAN | Thyrotropin alpha chain | Homo | <M><D><Y><Y><R><K><Y><A><A><I><F><L><V><T><L><S><V><F><L><H><V><L><H><S><A><P><D><V><Q><D><C><P><E><C><T><L><Q><E><N><P><F><F><S><Q><P><G><A><P><I><L><Q><C><M><G><C><C><F><S><R><A><Y><P><T><P><L><R><S><K><K><T><M><L><V><Q><K><N><V><T><S><E><S><T><C><C><V><A><K><S><Y><N><R><V><T><V><M><G><G><F><K><V><E><N><H><T><A><C><H... | Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pat... | P01215 |
Q5JX71 | F209A_HUMAN | Protein FAM209A | Homo | <M><W><T><L><K><S><S><L><V><L><L><L><C><L><T><C><S><Y><A><F><M><F><S><S><L><R><Q><K><T><S><E><P><Q><G><K><V><Q><Y><G><E><H><F><R><I><R><Q><N><L><P><E><H><T><Q><G><W><L><G><S><K><W><L><W><L><L><F><V><V><V><P><F><V><I><L><Q><C><Q><R><D><S><E><K><N><K><E><Q><S><P><P><G><L><R><G><G><Q><L><H><S><P><L><K><K><K><R><N><A><S><P... | May play a role in sperm acrosome biogenesis.<BOP> | Q5JX71 |
Q08752 | PPID_HUMAN | Rotamase D | Homo | <M><S><H><P><S><P><Q><A><K><P><S><N><P><S><N><P><R><V><F><F><D><V><D><I><G><G><E><R><V><G><R><I><V><L><E><L><F><A><D><I><V><P><K><T><A><E><N><F><R><A><L><C><T><G><E><K><G><I><G><H><T><T><G><K><P><L><H><F><K><G><C><P><F><H><R><I><I><K><K><F><M><I><Q><G><G><D><F><S><N><Q><N><G><T><G><G><E><S><I><Y><G><E><K><F><E><D><E><N... | (Microbial infection) May be involved in hepatitis C virus (HCV) replication and release.<BOP> | Q08752 |
O14645 | IDLC_HUMAN | hp28 | Homo | <M><I><P><P><A><D><S><L><L><K><Y><D><T><P><V><L><V><S><R><N><T><E><K><R><S><P><K><A><R><L><L><K><V><S><P><Q><Q><P><G><P><S><G><S><A><P><Q><P><P><K><T><K><L><P><S><T><P><C><V><P><D><P><T><K><Q><A><E><E><I><L><N><A><I><L><P><P><R><E><W><V><E><D><T><Q><L><W><I><Q><Q><V><S><S><T><P><S><T><R><M><D><V><V><H><L><Q><E><Q><L><D... | May play a dynamic role in flagellar motility.<BOP> | O14645 |
P0DJD8 | PEPA3_HUMAN | Pepsinogen-3 | Homo | <M><K><W><L><L><L><L><G><L><V><A><L><S><E><C><I><M><Y><K><V><P><L><I><R><K><K><S><L><R><R><T><L><S><E><R><G><L><L><K><D><F><L><K><K><H><N><L><N><P><A><R><K><Y><F><P><Q><W><K><A><P><T><L><V><D><E><Q><P><L><E><N><Y><L><D><M><E><Y><F><G><T><I><G><I><G><T><P><A><Q><D><F><T><V><V><F><D><T><G><S><S><N><L><W><V><P><S><V><Y><C... | Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.<BOP> | P0DJD8 |
P53370 | NUDT6_HUMAN | Protein GFG | Homo | <M><R><Q><P><L><S><W><G><R><W><R><A><M><L><A><R><T><Y><G><P><G><P><S><A><G><Y><R><W><A><S><G><A><Q><G><Y><V><R><N><P><P><V><G><A><C><D><L><Q><G><E><L><D><R><F><G><G><I><S><V><R><L><A><R><L><D><A><L><D><R><L><D><A><A><A><F><Q><K><G><L><Q><A><A><V><Q><Q><W><R><S><E><G><R><T><A><V><W><L><H><I><P><I><L><Q><S><R><F><I><A><P... | May contribute to the regulation of cell proliferation.<BOP> | P53370 |
Q8NGF4 | O5AP2_HUMAN | Olfactory receptor 5AP2 | Homo | <M><R><L><M><K><E><V><R><G><R><N><Q><T><E><V><T><E><F><L><L><L><G><L><S><D><N><P><D><L><Q><G><V><L><F><A><L><F><L><L><I><Y><M><A><N><M><V><G><N><L><G><M><I><V><L><I><K><I><D><L><C><L><H><T><P><M><Y><F><F><L><S><S><L><S><F><V><D><A><S><Y><S><S><S><V><T><P><K><M><L><V><N><L><M><A><E><N><K><A><I><S><F><H><G><C><A><A><Q><F... | Odorant receptor.<BOP> | Q8NGF4 |
P63000 | RAC1_HUMAN | p21-Rac1 | Homo | <M><Q><A><I><K><C><V><V><V><G><D><G><A><V><G><K><T><C><L><L><I><S><Y><T><T><N><A><F><P><G><E><Y><I><P><T><V><F><D><N><Y><S><A><N><V><M><V><D><G><K><P><V><N><L><G><L><W><D><T><A><G><Q><E><D><Y><D><R><L><R><P><L><S><Y><P><Q><T><D><V><F><L><I><C><F><S><L><V><S><P><A><S><F><E><N><V><R><A><K><W><Y><P><E><V><R><H><H><C><P><N... | Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins . It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish ef... | P63000 |
Q8NHZ8 | CDC26_HUMAN | Cell division cycle protein 26 homolog | Homo | <M><L><R><R><K><P><T><R><L><E><L><K><L><D><D><I><E><E><F><E><N><I><R><K><D><L><E><T><R><K><K><Q><K><E><D><V><E><V><V><G><G><S><D><G><E><G><A><I><G><L><S><S><D><P><K><S><R><E><Q><M><I><N><D><R><I><G><Y><K><P><Q><P><K><P><N><N><R><S><S><Q><F><G><S><L><E><F> | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'L... | Q8NHZ8 |
Q9H6B4 | CLMP_HUMAN | Coxsackie- and adenovirus receptor-like membrane protein | Homo | <M><S><L><L><L><L><L><L><L><V><S><Y><Y><V><G><T><L><G><T><H><T><E><I><K><R><V><A><E><E><K><V><T><L><P><C><H><H><Q><L><G><L><P><E><K><D><T><L><D><I><E><W><L><L><T><D><N><E><G><N><Q><K><V><V><I><T><Y><S><S><R><H><V><Y><N><N><L><T><E><E><Q><K><G><R><V><A><F><A><S><N><F><L><A><G><D><A><S><L><Q><I><E><P><L><K><P><S><D><E><G... | May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.<BOP> | Q9H6B4 |
Q6PCB6 | AB17C_HUMAN | Alpha/beta hydrolase domain-containing protein 17C | Homo | <M><P><E><P><G><P><R><M><N><G><F><S><L><G><E><L><C><W><L><F><C><C><P><P><C><P><S><R><I><A><A><K><L><A><F><L><P><P><E><P><T><Y><T><V><L><A><P><E><Q><R><G><A><G><A><S><A><P><A><P><A><Q><A><T><A><A><A><A><A><A><Q><P><A><P><Q><Q><P><E><E><G><A><G><A><G><P><G><A><C><S><L><H><L><S><E><R><A><D><W><Q><Y><S><Q><R><E><L><D><A><V... | Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS and DLG4/PSD95.<BOP> | Q6PCB6 |
Q9NX57 | RAB20_HUMAN | Ras-related protein Rab-20 | Homo | <M><R><K><P><D><S><K><I><V><L><L><G><D><M><N><V><G><K><T><S><L><L><Q><R><Y><M><E><R><R><F><P><D><T><V><S><T><V><G><G><A><F><Y><L><K><Q><W><R><S><Y><N><I><S><I><W><D><T><A><G><R><E><Q><F><H><G><L><G><S><M><Y><C><R><G><A><A><A><I><I><L><T><Y><D><V><N><H><R><Q><S><L><V><E><L><E><D><R><F><L><G><L><T><D><T><A><S><K><D><C><L... | Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.<BOP> | Q9NX57 |
Q3ZCQ3 | F174B_HUMAN | Membrane protein FAM174B | Homo | <M><R><A><V><P><L><P><A><P><L><L><P><L><L><L><L><A><L><L><A><A><P><A><A><R><A><S><R><A><E><S><V><S><A><P><W><P><E><P><E><R><E><S><R><P><P><P><G><P><G><P><G><N><T><T><R><F><G><S><G><A><A><G><G><S><G><S><S><S><S><N><S><S><G><D><A><L><V><T><R><I><S><I><L><L><R><D><L><P><T><L><K><A><A><V><I><V><A><F><A><F><T><T><L><L><I><A... | Essential for Golgi structural integrity.<BOP> | Q3ZCQ3 |
Q12834 | CDC20_HUMAN | p55CDC | Homo | <M><A><Q><F><A><F><E><S><D><L><H><S><L><L><Q><L><D><A><P><I><P><N><A><P><P><A><R><W><Q><R><K><A><K><E><A><A><G><P><A><P><S><P><M><R><A><A><N><R><S><H><S><A><G><R><T><P><G><R><T><P><G><K><S><S><S><K><V><Q><T><T><P><S><K><P><G><G><D><R><Y><I><P><H><R><S><A><A><Q><M><E><V><A><S><F><L><L><S><K><E><N><Q><P><E><N><S><Q><T><P... | Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates.... | Q12834 |
Q96MK3 | FA20A_HUMAN | Pseudokinase FAM20A | Homo | <M><P><G><L><R><R><D><R><L><L><T><L><L><L><L><G><A><L><L><S><A><D><L><Y><F><H><L><W><P><Q><V><Q><R><Q><L><R><P><R><E><R><P><R><G><C><P><C><T><G><R><A><S><S><L><A><R><D><S><A><A><A><A><S><D><P><G><T><I><V><H><N><F><S><R><T><E><P><R><T><E><P><A><G><G><S><H><S><G><S><S><S><K><L><Q><A><L><F><A><H><P><L><Y><N><V><P><E><E><P... | Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals.<BOP... | Q96MK3 |
Q08380 | LG3BP_HUMAN | Tumor-associated antigen 90K | Homo | <M><T><P><P><R><L><F><W><V><W><L><L><V><A><G><T><Q><G><V><N><D><G><D><M><R><L><A><D><G><G><A><T><N><Q><G><R><V><E><I><F><Y><R><G><Q><W><G><T><V><C><D><N><L><W><D><L><T><D><A><S><V><V><C><R><A><L><G><F><E><N><A><T><Q><A><L><G><R><A><A><F><G><Q><G><S><G><P><I><M><L><D><E><V><Q><C><T><G><T><E><A><S><L><A><D><C><K><S><L><G... | Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.<BOP> | Q08380 |
Q9H4F8 | SMOC1_HUMAN | Secreted modular calcium-binding protein 1 | Homo | <M><L><P><A><R><C><A><R><L><L><T><P><H><L><L><L><V><L><V><Q><L><S><P><A><R><G><H><R><T><T><G><P><R><F><L><I><S><D><R><D><P><Q><C><N><L><H><C><S><R><T><Q><P><K><P><I><C><A><S><D><G><R><S><Y><E><S><M><C><E><Y><Q><R><A><K><C><R><D><P><T><L><G><V><V><H><R><G><R><C><K><D><A><G><Q><S><K><C><R><L><E><R><A><Q><A><L><E><Q><A><K... | Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation.<BOP> | Q9H4F8 |
Q9BQP7 | MGME1_HUMAN | Mitochondrial genome maintenance exonuclease 1 | Homo | <M><K><M><K><L><F><Q><T><I><C><R><Q><L><R><S><S><K><F><S><V><E><S><A><A><L><V><A><F><S><T><S><S><Y><S><C><G><R><K><K><K><V><N><P><Y><E><E><V><D><Q><E><K><Y><S><N><L><V><Q><S><V><L><S><S><R><G><V><A><Q><T><P><G><S><V><E><E><D><A><L><L><C><G><P><V><S><K><H><K><L><P><N><Q><G><E><D><R><R><V><P><Q><N><W><F><P><I><F><N><P><E... | Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair,... | Q9BQP7 |
P05111 | INHA_HUMAN | Inhibin alpha chain | Homo | <M><V><L><H><L><L><L><F><L><L><L><T><P><Q><G><G><H><S><C><Q><G><L><E><L><A><R><E><L><V><L><A><K><V><R><A><L><F><L><D><A><L><G><P><P><A><V><T><R><E><G><G><D><P><G><V><R><R><L><P><R><R><H><A><L><G><G><F><T><H><R><G><S><E><P><E><E><E><E><D><V><S><Q><A><I><L><F><P><A><T><D><A><S><C><E><D><K><S><A><A><R><G><L><A><Q><E><A><E... | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid diffe... | P05111 |
Q9NPG2 | NGB_HUMAN | Neuroglobin | Homo | <M><E><R><P><E><P><E><L><I><R><Q><S><W><R><A><V><S><R><S><P><L><E><H><G><T><V><L><F><A><R><L><F><A><L><E><P><D><L><L><P><L><F><Q><Y><N><C><R><Q><F><S><S><P><E><D><C><L><S><S><P><E><F><L><D><H><I><R><K><V><M><L><V><I><D><A><A><V><T><N><V><E><D><L><S><S><L><E><E><Y><L><A><S><L><G><R><K><H><R><A><V><G><V><K><L><S><S><F><S... | Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxida... | Q9NPG2 |
P02675 | FIBB_HUMAN | Fibrinogen beta chain | Homo | <M><K><R><M><V><S><W><S><F><H><K><L><K><T><M><K><H><L><L><L><L><L><L><C><V><F><L><V><K><S><Q><G><V><N><D><N><E><E><G><F><F><S><A><R><G><H><R><P><L><D><K><K><R><E><E><A><P><S><L><R><P><A><P><P><P><I><S><G><G><G><Y><R><A><R><P><A><K><A><A><A><T><Q><K><K><V><E><R><K><A><P><D><A><G><G><C><L><H><A><D><P><D><L><G><V><L><C><P... | Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound rep... | P02675 |
Q7Z4W3 | KR193_HUMAN | Glycine/tyrosine-rich protein | Homo | <M><S><Y><Y><G><S><Y><Y><G><G><L><G><Y><G><C><G><G><F><G><G><L><G><Y><G><Y><G><C><G><C><G><S><F><R><R><L><G><S><G><C><G><Y><G><G><Y><G><Y><G><S><G><F><G><G><Y><G><Y><G><S><G><F><G><G><Y><G><Y><G><C><Y><R><P><S><Y><Y><G><G><Y><G><F><S><G><F><Y> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q7Z4W3 |
Q04741 | EMX1_HUMAN | Empty spiracles-like protein 1 | Homo | <M><C><L><A><G><C><T><P><R><K><A><A><A><P><G><R><G><A><L><P><R><A><R><L><P><R><T><A><P><A><A><A><T><M><F><Q><P><A><A><K><R><G><F><T><I><E><S><L><V><A><K><D><G><G><T><G><G><G><T><G><G><G><G><A><G><S><H><L><L><A><A><A><A><S><E><E><P><L><R><P><T><A><L><N><Y><P><H><P><S><A><A><E><A><A><F><V><S><G><F><P><A><A><A><A><A><G><A... | Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.<BOP> | Q04741 |
Q8N8L2 | ZN491_HUMAN | Zinc finger protein 491 | Homo | <M><G><E><R><L><F><E><S><A><E><G><S><Q><C><G><E><T><F><T><Q><V><P><E><D><M><L><N><K><K><T><L><P><G><V><K><S><C><E><S><G><T><C><G><E><I><F><M><G><Y><S><S><F><N><R><N><I><R><T><D><T><G><H><Q><P><H><K><C><Q><K><F><L><E><K><P><Y><K><H><K><Q><R><R><K><A><L><S><H><S><H><C><F><R><T><H><E><R><P><H><T><R><E><K><P><F><D><C><K><E... | May be involved in transcriptional regulation.<BOP> | Q8N8L2 |
P26599 | PTBP1_HUMAN | Heterogeneous nuclear ribonucleoprotein I | Homo | <M><D><G><I><V><P><D><I><A><V><G><T><K><R><G><S><D><E><L><F><S><T><C><V><T><N><G><P><F><I><M><S><S><N><S><A><S><A><A><N><G><N><D><S><K><K><F><K><G><D><S><R><S><A><G><V><P><S><R><V><I><H><I><R><K><L><P><I><D><V><T><E><G><E><V><I><S><L><G><L><P><F><G><K><V><T><N><L><L><M><L><K><G><K><N><Q><A><F><I><E><M><N><T><E><E><A><A... | Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote... | P26599 |
P47224 | MSS4_HUMAN | Rab-interacting factor | Homo | <M><E><P><A><E><Q><P><S><E><L><V><S><A><E><G><R><N><R><K><A><V><L><C><Q><R><C><G><S><R><V><L><Q><P><G><T><A><L><F><S><R><R><Q><L><F><L><P><S><M><R><K><K><P><A><L><S><D><G><S><N><P><D><G><D><L><L><Q><E><H><W><L><V><E><D><M><F><I><F><E><N><V><G><F><T><K><D><V><G><N><I><K><F><L><V><C><A><D><C><E><I><G><P><I><G><W><H><C><L... | Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1, RAB3A and RAB10, but is less active on these proteins than on the SEC4 protein . Might play a general role in vesicular transport.<BOP> | P47224 |
Q5JPI9 | EFMT2_HUMAN | Protein-lysine N-methyltransferase METTL10 | Homo | <M><S><S><G><A><D><G><G><G><G><A><A><V><A><A><R><S><D><K><G><S><P><G><E><D><G><F><V><P><S><A><L><G><T><R><E><H><W><D><A><V><Y><E><R><E><L><Q><T><F><R><E><Y><G><D><T><G><E><I><W><F><G><E><E><S><M><N><R><L><I><R><W><M><Q><K><H><K><I><P><L><D><A><S><V><L><D><I><G><T><G><N><G><V><F><L><V><E><L><A><K><F><G><F><S><N><I><T><G... | Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.<BOP> | Q5JPI9 |
P11766 | ADHX_HUMAN | S-(hydroxymethyl)glutathione dehydrogenase | Homo | <M><A><N><E><V><I><K><C><K><A><A><V><A><W><E><A><G><K><P><L><S><I><E><E><I><E><V><A><P><P><K><A><H><E><V><R><I><K><I><I><A><T><A><V><C><H><T><D><A><Y><T><L><S><G><A><D><P><E><G><C><F><P><V><I><L><G><H><E><G><A><G><I><V><E><S><V><G><E><G><V><T><K><L><K><A><G><D><T><V><I><P><L><Y><I><P><Q><C><G><E><C><K><F><C><L><N><P><K... | Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione . Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate . C... | P11766 |
Q9H7C4 | SYNCI_HUMAN | Syncoilin-1 | Homo | <M><A><S><P><E><P><R><R><G><G><D><G><A><A><Q><A><A><R><K><T><R><V><E><A><N><S><P><L><P><K><N><S><G><S><L><N><E><A><E><A><L><N><P><E><V><T><L><S><S><E><G><S><L><N><L><E><D><I><L><Y><L><E><D><T><G><D><L><D><E><T><L><Y><V><Q><E><T><E><K><A><E><E><A><L><Y><I><E><E><A><M><Q><P><D><E><A><L><H><V><E><E><P><G><N><P><E><E><T><V... | Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF protei... | Q9H7C4 |
P30613 | KPYR_HUMAN | Red cell/liver pyruvate kinase | Homo | <M><S><I><Q><E><N><I><S><S><L><Q><L><R><S><W><V><S><K><S><Q><R><D><L><A><K><S><I><L><I><G><A><P><G><G><P><A><G><Y><L><R><R><A><S><V><A><Q><L><T><Q><E><L><G><T><A><F><F><Q><Q><Q><Q><L><P><A><A><M><A><D><T><F><L><E><H><L><C><L><L><D><I><D><S><E><P><V><A><A><R><S><T><S><I><I><A><T><I><G><P><A><S><R><S><V><E><R><L><K><E><M... | Pyruvate kinase that catalyzes the conversion of phosphoenolpyruvate to pyruvate with the synthesis of ATP, and which plays a key role in glycolysis.<BOP> | P30613 |
Q8NG97 | OR2Z1_HUMAN | Olfactory receptor OR19-4 | Homo | <M><G><D><V><N><Q><S><V><A><S><D><F><I><L><V><G><L><F><S><H><S><G><S><R><Q><L><L><F><S><L><V><A><V><M><F><V><I><G><L><L><G><N><T><V><L><L><F><L><I><R><V><D><S><R><L><H><T><P><M><Y><F><L><L><S><Q><L><S><L><F><D><I><G><C><P><M><V><T><I><P><K><M><A><S><D><F><L><R><G><E><G><A><T><S><Y><G><G><G><A><A><Q><I><F><F><L><T><L><M... | Odorant receptor.<BOP> | Q8NG97 |
Q96CX3 | ZN501_HUMAN | Zinc finger protein 52 | Homo | <M><N><S><S><Q><I><S><L><R><M><K><H><G><R><V><N><M><Q><K><K><P><S><K><C><S><E><C><G><K><F><F><T><Q><R><S><S><L><T><Q><H><Q><R><I><H><R><G><E><K><P><Y><V><C><S><E><C><G><S><C><F><R><K><Q><S><N><L><T><Q><H><L><R><I><H><T><G><E><K><P><Y><K><C><N><E><C><E><K><A><F><Q><T><K><A><I><L><V><Q><H><L><R><I><H><T><G><E><K><P><Y><K... | May be involved in transcriptional regulation. Essential for Golgi structural integrity .<BOP> | Q96CX3 |
Q8IU57 | INLR1_HUMAN | Likely interleukin or cytokine receptor 2 | Homo | <M><A><G><P><E><R><W><G><P><L><L><L><C><L><L><Q><A><A><P><G><R><P><R><L><A><P><P><Q><N><V><T><L><L><S><Q><N><F><S><V><Y><L><T><W><L><P><G><L><G><N><P><Q><D><V><T><Y><F><V><A><Y><Q><S><S><P><T><R><R><R><W><R><E><V><E><E><C><A><G><T><K><E><L><L><C><S><M><M><C><L><K><K><Q><D><L><Y><N><K><F><K><G><R><V><R><T><V><S><P><S><S... | The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the ce... | Q8IU57 |
Q6NT55 | CP4FN_HUMAN | Cytochrome P450 4F22 | Homo | <M><L><P><I><T><D><R><L><L><H><L><L><G><L><E><K><T><A><F><R><I><Y><A><V><S><T><L><L><L><F><L><L><F><F><L><F><R><L><L><L><R><F><L><R><L><C><R><S><F><Y><I><T><C><R><R><L><R><C><F><P><Q><P><P><R><R><N><W><L><L><G><H><L><G><M><Y><L><P><N><E><A><G><L><Q><D><E><K><K><V><L><D><N><M><H><H><V><L><L><V><W><M><G><P><V><L><P><L><L... | A cytochrome P450 monooxygenase involved in epidermal ceramide biosynthesis. Hydroxylates the terminal carbon (omega-hydroxylation) of ultra-long-chain fatty acyls (C28-C36) prior to ceramide synthesis . Contributes to the synthesis of three classes of omega-hydroxy-ultra-long chain fatty acylceramides having sphingosi... | Q6NT55 |
Q8IZJ0 | IFNL2_HUMAN | Interleukin-28A | Homo | <M><K><L><D><M><T><G><D><C><T><P><V><L><V><L><M><A><A><V><L><T><V><T><G><A><V><P><V><A><R><L><H><G><A><L><P><D><A><R><G><C><H><I><A><Q><F><K><S><L><S><P><Q><E><L><Q><A><F><K><R><A><K><D><A><L><E><E><S><L><L><L><K><D><C><R><C><H><S><R><L><F><P><R><T><W><D><L><R><Q><L><Q><V><R><E><R><P><M><A><L><E><A><E><L><A><L><T><L><K... | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/S... | Q8IZJ0 |
Q9Y394 | DHRS7_HUMAN | Short chain dehydrogenase/reductase family 34C member 1 | Homo | <M><N><W><E><L><L><L><W><L><L><V><L><C><A><L><L><L><L><L><V><Q><L><L><R><F><L><R><A><D><G><D><L><T><L><L><W><A><E><W><Q><G><R><R><P><E><W><E><L><T><D><M><V><V><W><V><T><G><A><S><S><G><I><G><E><E><L><A><Y><Q><L><S><K><L><G><V><S><L><V><L><S><A><R><R><V><H><E><L><E><R><V><K><R><R><C><L><E><N><G><N><L><K><E><K><D><I><L><V... | NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including steroids, retinoids and xenobiotics . Catalyzes the reduction/inactivation of 5alpha-dihydrotestosterone to 3alpha-androstanediol, with a possible role in the modulation of androgen receptor function... | Q9Y394 |
Q96D96 | HVCN1_HUMAN | Voltage sensor domain-only protein | Homo | <M><A><T><W><D><E><K><A><V><T><R><R><A><K><V><A><P><A><E><R><M><S><K><F><L><R><H><F><T><V><V><G><D><D><Y><H><A><W><N><I><N><Y><K><K><W><E><N><E><E><E><E><E><E><E><E><Q><P><P><P><T><P><V><S><G><E><E><G><R><A><A><A><P><D><V><A><P><A><P><G><P><A><P><R><A><P><L><D><F><R><G><M><L><R><K><L><F><S><S><H><R><F><Q><V><I><I><I><C... | Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.<BO... | Q96D96 |
Q92506 | DHB8_HUMAN | Testosterone 17-beta-dehydrogenase 8 | Homo | <M><A><S><Q><L><Q><N><R><L><R><S><A><L><A><L><V><T><G><A><G><S><G><I><G><R><A><V><S><V><R><L><A><G><E><G><A><T><V><A><A><C><D><L><D><R><A><A><A><Q><E><T><V><R><L><L><G><G><P><G><S><K><E><G><P><P><R><G><N><H><A><A><F><Q><A><D><V><S><E><A><R><A><A><R><C><L><L><E><Q><V><Q><A><C><F><S><R><P><P><S><V><V><V><S><C><A><G><I><T... | Required for the solubility and assembly of the heterotetramer 3-ketoacyl-[acyl carrier protein] (ACP) reductase functional complex (KAR or KAR1) that forms part of the mitochondrial fatty acid synthase (mtFAS). Alpha-subunit of the KAR complex that acts as a scaffold protein required for the stability of carbonyl redu... | Q92506 |
Q96CP7 | TLCD1_HUMAN | Calfacilitin | Homo | <M><P><R><L><L><H><P><A><L><P><L><L><L><G><A><T><L><T><F><R><A><L><R><R><A><L><C><R><L><P><L><P><V><H><V><R><A><D><P><L><R><T><W><R><W><H><N><L><L><V><S><F><A><H><S><I><V><S><G><I><W><A><L><L><C><V><W><Q><T><P><D><M><L><V><E><I><E><T><A><W><S><L><S><G><Y><L><L><V><C><F><S><A><G><Y><F><I><H><D><T><V><D><I><V><A><S><G><Q... | Regulates the composition and fluidity of the plasma membrane . Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity . Does not appear to have any effect on LCPUFA synthesis .<BOP> | Q96CP7 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.