accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q5H9L2 | TCAL5_HUMAN | Transcription elongation factor S-II protein-like 5 | Homo | <M><E><K><L><Y><K><E><N><E><G><K><P><E><N><E><R><N><L><E><S><E><G><K><P><E><D><E><G><S><T><E><D><E><G><K><S><D><E><E><E><K><P><D><M><E><G><K><T><E><C><E><G><K><R><E><D><E><G><E><P><G><D><E><G><Q><L><E><D><E><G><N><Q><E><K><Q><G><K><S><E><G><E><D><K><P><Q><S><E><G><K><P><A><S><Q><A><K><P><E><S><Q><P><R><A><A><E><K><R><P... | May be involved in transcriptional regulation.<BOP> | Q5H9L2 |
P16444 | DPEP1_HUMAN | Renal dipeptidase | Homo | <M><W><S><G><W><W><L><W><P><L><V><A><V><C><T><A><D><F><F><R><D><E><A><E><R><I><M><R><D><S><P><V><I><D><G><H><N><D><L><P><W><Q><L><L><D><M><F><N><N><R><L><Q><D><E><R><A><N><L><T><T><L><A><G><T><H><T><N><I><P><K><L><R><A><G><F><V><G><G><Q><F><W><S><V><Y><T><P><C><D><T><Q><N><K><D><A><V><R><R><T><L><E><Q><M><D><V><V><H><R... | Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.<BOP> | P16444 |
Q9ULM2 | ZN490_HUMAN | Zinc finger protein 490 | Homo | <M><R><R><N><S><S><L><S><F><Q><M><E><R><P><L><E><E><Q><V><Q><S><K><W><S><S><S><Q><G><R><T><G><T><G><G><S><D><V><L><Q><M><Q><N><S><E><H><H><G><Q><S><I><K><T><Q><T><D><S><I><S><L><E><D><V><A><V><N><F><T><L><E><E><W><A><L><L><D><P><G><Q><R><N><I><Y><R><D><V><M><R><A><T><F><K><N><L><A><C><I><G><E><K><W><K><D><Q><D><I><E><D... | May be involved in transcriptional regulation.<BOP> | Q9ULM2 |
Q06587 | RING1_HUMAN | Really interesting new gene 1 protein | Homo | <M><T><T><P><A><N><A><Q><N><A><S><K><T><W><E><L><S><L><Y><E><L><H><R><T><P><Q><E><A><I><M><D><G><T><E><I><A><V><S><P><R><S><L><H><S><E><L><M><C><P><I><C><L><D><M><L><K><N><T><M><T><T><K><E><C><L><H><R><F><C><S><D><C><I><V><T><A><L><R><S><G><N><K><E><C><P><T><C><R><K><K><L><V><S><K><R><S><L><R><P><D><P><N><F><D><A><L><I... | Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation o... | Q06587 |
Q8WWU5 | TCP11_HUMAN | T-complex protein 11 homolog | Homo | <M><P><D><V><K><E><S><V><P><P><K><Y><P><G><D><S><E><G><R><S><C><K><P><E><T><S><G><P><P><Q><E><D><K><S><G><S><E><D><P><P><P><F><L><S><V><T><G><L><T><E><T><V><N><E><V><S><K><L><S><N><K><I><G><M><N><C><D><Y><Y><M><E><E><K><V><L><P><P><S><S><L><E><G><K><V><K><E><T><V><H><N><A><F><W><D><H><L><K><E><Q><L><S><A><T><P><P><D><F... | Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway.<BOP> | Q8WWU5 |
Q9HAT8 | PELI2_HUMAN | RING-type E3 ubiquitin transferase pellino homolog 2 | Homo | <M><F><S><P><G><Q><E><E><H><C><A><P><N><K><E><P><V><K><Y><G><E><L><V><V><L><G><Y><N><G><A><L><P><N><G><D><R><G><R><R><K><S><R><F><A><L><Y><K><R><P><K><A><N><G><V><K><P><S><T><V><H><V><I><S><T><P><Q><A><S><K><A><I><S><C><K><G><Q><H><S><I><S><Y><T><L><S><R><N><Q><T><V><V><V><E><Y><T><H><D><K><D><T><D><M><F><Q><V><G><R><S... | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitina... | Q9HAT8 |
P11912 | CD79A_HUMAN | Surface IgM-associated protein | Homo | <M><P><G><G><P><G><V><L><Q><A><L><P><A><T><I><F><L><L><F><L><L><S><A><V><Y><L><G><P><G><C><Q><A><L><W><M><H><K><V><P><A><S><L><M><V><S><L><G><E><D><A><H><F><Q><C><P><H><N><S><S><N><N><A><N><V><T><W><W><R><V><L><H><G><N><Y><T><W><P><P><E><F><L><G><P><G><E><D><P><N><G><T><L><I><I><Q><N><V><N><K><S><H><G><G><I><Y><V><C><R... | Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for effici... | P11912 |
Q14032 | BAAT_HUMAN | Long-chain fatty-acyl-CoA hydrolase | Homo | <M><I><Q><L><T><A><T><P><V><S><A><L><V><D><E><P><V><H><I><R><A><T><G><L><I><P><F><Q><M><V><S><F><Q><A><S><L><E><D><E><N><G><D><M><F><Y><S><Q><A><H><Y><R><A><N><E><F><G><E><V><D><L><N><H><A><S><S><L><G><G><D><Y><M><G><V><H><P><M><G><L><F><W><S><L><K><P><E><K><L><L><T><R><L><L><K><R><D><V><M><N><R><P><F><Q><V><Q><V><K><L... | Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine . More than 95% of the BAs are N-acyl amidates with glycine and taurine . Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism . This conjuga... | Q14032 |
Q13326 | SGCG_HUMAN | 35 kDa dystrophin-associated glycoprotein | Homo | <M><V><R><E><Q><Y><T><T><A><T><E><G><I><C><I><E><R><P><E><N><Q><Y><V><Y><K><I><G><I><Y><G><W><R><K><R><C><L><Y><L><F><V><L><L><L><L><I><I><L><V><V><N><L><A><L><T><I><W><I><L><K><V><M><W><F><S><P><A><G><M><G><H><L><C><V><T><K><D><G><L><R><L><E><G><E><S><E><F><L><F><P><L><Y><A><K><E><I><H><S><R><V><D><S><S><L><L><L><Q><S... | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.<BOP> | Q13326 |
P0DSN6 | T2R33_HUMAN | Putative taste receptor type 2 member 33 | Homo | <M><V><Y><F><L><P><I><I><F><S><I><L><V><V><F><A><F><V><L><G><N><F><S><N><G><F><I><A><L><V><N><V><I><D><W><V><K><R><Q><K><I><S><S><A><D><Q><I><L><T><A><L><V><V><S><R><V><G><L><L><W><V><I><L><L><H><W><Y><A><N><V><F><N><S><A><L><Y><S><L><E><V><R><I><V><A><S><N><I><S><A><V><I><N><H><F><S><I><W><L><A><A><S><L><S><I><F><Y><L... | Putative taste receptor which may play a role in the perception of bitterness.<BOP> | P0DSN6 |
Q9UIG8 | SO3A1_HUMAN | Solute carrier family 21 member 11 | Homo | <M><Q><G><K><K><P><G><G><S><S><G><G><G><R><S><G><E><L><Q><G><D><E><A><Q><R><N><K><K><K><K><K><K><V><S><C><F><S><N><I><K><I><F><L><V><S><E><C><A><L><M><L><A><Q><G><T><V><G><A><Y><L><V><S><V><L><T><T><L><E><R><R><F><N><L><Q><S><A><D><V><G><V><I><A><S><S><F><E><I><G><N><L><A><L><I><L><F><V><S><Y><F><G><A><R><G><H><R><P><R... | Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate . Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin n... | Q9UIG8 |
Q9NXV6 | CARF_HUMAN | Collaborator of ARF | Homo | <M><A><Q><E><V><S><E><Y><L><S><Q><N><P><R><V><A><A><W><V><E><A><L><R><C><D><G><E><T><D><K><H><W><R><H><R><R><D><F><L><L><R><N><A><G><D><L><A><P><A><G><G><A><A><S><A><S><T><D><E><A><A><D><A><E><S><G><T><R><N><R><Q><L><Q><Q><L><I><S><F><S><M><A><W><A><N><H><V><F><L><G><C><R><Y><P><Q><K><V><M><D><K><I><L><S><M><A><E><G><I... | Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.<BOP> | Q9NXV6 |
Q8N5D0 | WDTC1_HUMAN | WD and tetratricopeptide repeats protein 1 | Homo | <M><A><K><V><N><I><T><R><D><L><I><R><R><Q><I><K><E><R><G><A><L><S><F><E><R><R><Y><H><V><T><D><P><F><I><R><R><L><G><L><E><A><E><L><Q><G><H><S><G><C><V><N><C><L><E><W><N><E><K><G><D><L><L><A><S><G><S><D><D><Q><H><T><I><V><W><D><P><L><H><H><K><K><L><L><S><M><H><T><G><H><T><A><N><I><F><S><V><K><F><L><P><H><A><G><D><R><I><L... | May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.<BOP> | Q8N5D0 |
A8MV23 | SERP3_HUMAN | Serpin E3 | Homo | <M><P><P><F><L><I><T><L><F><L><F><H><S><C><C><L><R><A><N><G><H><L><R><E><G><M><T><L><L><K><T><E><F><A><L><H><L><Y><Q><S><V><A><A><C><R><N><E><T><N><F><V><I><S><P><A><G><V><S><L><P><L><E><I><L><Q><F><G><A><E><G><S><T><G><Q><Q><L><A><D><A><L><G><Y><T><V><H><D><K><R><V><K><D><F><L><H><A><V><Y><A><T><L><P><T><S><S><Q><G><T... | Probable serine protease inhibitor.<BOP> | A8MV23 |
Q53G44 | IF44L_HUMAN | Interferon-induced protein 44-like | Homo | <M><E><V><T><T><R><L><T><W><N><D><E><N><H><L><R><K><L><L><G><N><V><S><L><S><L><L><Y><K><S><S><V><H><G><G><S><I><E><D><M><V><E><R><C><S><R><Q><G><C><T><I><T><M><A><Y><I><D><Y><N><M><I><V><A><F><M><L><G><N><Y><I><N><L><H><E><S><S><T><E><P><N><D><S><L><W><F><S><L><Q><K><K><N><D><T><T><E><I><E><T><L><L><L><N><T><A><P><K><I... | Type I interferon-stimulated gene (ISG) that plays a critical role in antiviral and antibacterial activity . During bacterial infection, promotes macrophage differentiation and facilitates inflammatory cytokine secretion . Plays a role in the control of respiratory syncytial virus/RSV infection, reducing the ability of... | Q53G44 |
P22309 | UD11_HUMAN | UDP-glucuronosyltransferase 1A isoform 1 | Homo | <M><A><V><E><S><Q><G><G><R><P><L><V><L><G><L><L><L><C><V><L><G><P><V><V><S><H><A><G><K><I><L><L><I><P><V><D><G><S><H><W><L><S><M><L><G><A><I><Q><Q><L><Q><Q><R><G><H><E><I><V><V><L><A><P><D><A><S><L><Y><I><R><D><G><A><F><Y><T><L><K><T><Y><P><V><P><F><Q><R><E><D><V><K><E><S><F><V><S><L><G><H><N><V><F><E><N><D><S><F><L><Q... | Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1.<BOP> | P22309 |
P60371 | KR106_HUMAN | Keratin-associated protein 18.6 | Homo | <M><A><A><S><T><M><S><V><C><S><S><D><L><S><Y><G><S><R><V><C><L><P><G><S><C><D><S><C><S><D><S><W><Q><V><D><D><C><P><E><S><C><C><E><P><P><C><C><A><P><A><P><C><L><S><L><V><C><T><P><V><S><R><V><S><S><P><C><C><P><V><T><C><E><P><S><P><C><Q><S><G><C><T><S><S><C><T><P><S><C><C><Q><Q><S><S><C><Q><L><A><C><C><A><S><S><P><C><Q><Q... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | P60371 |
Q96N66 | MBOA7_HUMAN | Membrane-bound O-acyltransferase domain-containing protein 7 | Homo | <M><S><P><E><E><W><T><Y><L><V><V><L><L><I><S><I><P><I><G><F><L><F><K><K><A><G><P><G><L><K><R><W><G><A><A><A><V><G><L><G><L><T><L><F><T><C><G><P><H><T><L><H><S><L><V><T><I><L><G><T><W><A><L><I><Q><A><Q><P><C><S><C><H><A><L><A><L><A><W><T><F><S><Y><L><L><F><F><R><A><L><S><L><L><G><L><P><T><P><T><P><F><T><N><A><V><Q><L><L... | Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remode... | Q96N66 |
O94927 | HAUS5_HUMAN | HAUS augmin-like complex subunit 5 | Homo | <M><E><L><A><Q><E><A><R><E><L><G><C><W><A><V><E><E><M><G><V><P><V><A><A><R><A><P><E><S><T><L><R><R><L><C><L><G><Q><G><A><D><I><W><A><Y><I><L><Q><H><V><H><S><Q><R><T><V><K><K><I><R><G><N><L><L><W><Y><G><H><Q><D><S><P><Q><V><R><R><K><L><E><L><E><A><A><V><T><R><L><R><A><E><I><Q><E><L><D><Q><S><L><E><L><M><E><R><D><T><E><A... | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.<BOP> | O94927 |
A0A075B6L2 | TVG11_HUMAN | Probable non-functional T cell receptor gamma variable 11 | Homo | <M><P><L><V><V><A><V><I><F><F><S><L><W><V><F><A><L><G><Q><L><E><Q><P><E><I><S><I><S><R><P><A><N><K><S><A><H><I><S><W><K><A><S><I><Q><G><F><S><S><K><I><I><H><W><Y><W><Q><K><P><N><K><G><L><E><Y><L><L><H><V><F><L><T><I><S><A><Q><D><C><S><G><G><K><T><K><K><L><E><V><S><K><N><A><H><T><S><T><S><T><L><K><I><K><F><L><E><K><E><D... | Probable non-functional open reading frame (ORF) of V region of the variable domain of T cell receptor (TR) gamma chain . Non-functional ORF generally cannot participate in the synthesis of a productive T cell receptor (TR) chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or... | A0A075B6L2 |
P42772 | CDN2B_HUMAN | p15-INK4b | Homo | <M><R><E><E><N><K><G><M><P><S><G><G><G><S><D><E><G><L><A><S><A><A><A><R><G><L><V><E><K><V><R><Q><L><L><E><A><G><A><D><P><N><G><V><N><R><F><G><R><R><A><I><Q><V><M><M><M><G><S><A><R><V><A><E><L><L><L><L><H><G><A><E><P><N><C><A><D><P><A><T><L><T><R><P><V><H><D><A><A><R><E><G><F><L><D><T><L><V><V><L><H><R><A><G><A><R><L><D... | Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.<BOP> | P42772 |
Q9NRR3 | C42S2_HUMAN | Small effector of CDC42 protein 2 | Homo | <M><S><E><F><W><L><C><F><N><C><C><I><A><E><Q><P><Q><P><K><R><R><R><R><I><D><R><S><M><I><G><E><P><T><N><F><V><H><T><A><H><V><G><S><G><D><L><F><S><G><M><N><S><V><S><S><I><Q><N><Q><M><Q><S><K><G><G><Y><G><G><G><M><P><A><N><V><Q><M><Q><L><V><D><T><K><A><G> | Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events... | Q9NRR3 |
O75771 | RA51D_HUMAN | TRAD | Homo | <M><G><V><L><R><V><G><L><C><P><G><L><T><E><E><M><I><Q><L><L><R><S><H><R><I><K><T><V><V><D><L><V><S><A><D><L><E><E><V><A><Q><K><C><G><L><S><Y><K><A><L><V><A><L><R><R><V><L><L><A><Q><F><S><A><F><P><V><N><G><A><D><L><Y><E><E><L><K><T><S><T><A><I><L><S><T><G><I><G><S><L><D><K><L><L><D><A><G><L><Y><T><G><E><V><T><E><I><V><G... | Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent... | O75771 |
Q9UGF6 | OR5V1_HUMAN | Olfactory receptor OR6-26 | Homo | <M><E><R><K><N><Q><T><A><I><T><E><F><I><I><L><G><F><S><N><L><N><E><L><Q><F><L><L><F><T><I><F><F><L><T><Y><F><C><T><L><G><G><N><I><L><I><I><L><T><T><V><T><D><P><H><L><H><T><P><M><Y><Y><F><L><G><N><L><A><F><I><D><I><C><Y><T><T><S><N><V><P><Q><M><M><V><H><L><L><S><K><K><K><S><I><S><Y><V><G><C><V><V><Q><L><F><A><F><V><F><F... | Odorant receptor.<BOP> | Q9UGF6 |
Q6UXF1 | TM108_HUMAN | Retrolinkin | Homo | <M><K><R><S><L><Q><A><L><Y><C><Q><L><L><S><F><L><L><I><L><A><L><T><E><A><L><A><F><A><I><Q><E><P><S><P><R><E><S><L><Q><V><L><P><S><G><T><P><P><G><T><M><V><T><A><P><H><S><S><T><R><H><T><S><V><V><M><L><T><P><N><P><D><G><P><P><S><Q><A><A><A><P><M><A><T><P><T><P><R><A><E><G><H><P><P><T><H><T><I><S><T><I><A><A><T><V><T><A><P... | Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of ... | Q6UXF1 |
O96033 | MOC2A_HUMAN | Sulfur carrier protein MOCS2A | Homo | <M><V><P><L><C><Q><V><E><V><L><Y><F><A><K><S><A><E><I><T><G><V><R><S><E><T><I><S><V><P><Q><E><I><K><A><L><Q><L><W><K><E><I><E><T><R><H><P><G><L><A><D><V><R><N><Q><I><I><F><A><V><R><Q><E><Y><V><E><L><G><D><Q><L><L><V><L><Q><P><G><D><E><I><A><V><I><P><P><I><S><G><G> | Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by be... | O96033 |
Q8NGE3 | O10P1_HUMAN | Olfactory receptor OR12-7 | Homo | <M><A><G><E><N><H><T><T><L><P><E><F><L><L><L><G><F><S><D><L><K><A><L><Q><G><P><L><F><W><V><V><L><L><V><Y><L><V><T><L><L><G><N><S><L><I><I><L><L><T><Q><V><S><P><A><L><H><S><P><M><Y><F><F><L><R><Q><L><S><V><V><E><L><F><Y><T><T><D><I><V><P><R><T><L><A><N><L><G><S><P><H><P><Q><A><I><S><F><Q><G><C><A><A><Q><M><Y><V><F><I><V... | Odorant receptor.<BOP> | Q8NGE3 |
Q86WT1 | TT30A_HUMAN | Tetratricopeptide repeat protein 30A | Homo | <M><A><G><L><S><G><A><Q><I><P><D><G><E><F><T><A><L><V><Y><R><L><I><R><D><A><R><Y><A><E><A><V><Q><L><L><G><R><E><L><Q><R><S><P><R><S><R><A><G><L><S><L><L><G><Y><C><Y><Y><R><L><Q><E><F><A><L><A><A><E><C><Y><E><Q><L><G><Q><L><H><P><E><L><E><Q><Y><R><L><Y><Q><A><Q><A><L><Y><K><A><C><L><Y><P><E><A><T><R><V><A><F><L><L><L><D... | Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.<BOP> | Q86WT1 |
P04424 | ARLY_HUMAN | Arginosuccinase | Homo | <M><A><S><E><S><G><K><L><W><G><G><R><F><V><G><A><V><D><P><I><M><E><K><F><N><A><S><I><A><Y><D><R><H><L><W><E><V><D><V><Q><G><S><K><A><Y><S><R><G><L><E><K><A><G><L><L><T><K><A><E><M><D><Q><I><L><H><G><L><D><K><V><A><E><E><W><A><Q><G><T><F><K><L><N><S><N><D><E><D><I><H><T><A><N><E><R><R><L><K><E><L><I><G><A><T><A><G><K><L... | Catalyzes the reversible cleavage of L-argininosuccinate to fumarate and L-arginine, an intermediate step reaction in the urea cycle mostly providing for hepatic nitrogen detoxification into excretable urea as well as de novo L-arginine synthesis in nonhepatic tissues . Essential regulator of intracellular and extracel... | P04424 |
Q96EP5 | DAZP1_HUMAN | Deleted in azoospermia-associated protein 1 | Homo | <M><N><N><S><G><A><D><E><I><G><K><L><F><V><G><G><L><D><W><S><T><T><Q><E><T><L><R><S><Y><F><S><Q><Y><G><E><V><V><D><C><V><I><M><K><D><K><T><T><N><Q><S><R><G><F><G><F><V><K><F><K><D><P><N><C><V><G><T><V><L><A><S><R><P><H><T><L><D><G><R><N><I><D><P><K><P><C><T><P><R><G><M><Q><P><E><R><T><R><P><K><E><G><W><Q><K><G><P><R><S... | RNA-binding protein, which may be required during spermatogenesis.<BOP> | Q96EP5 |
Q9H1P3 | OSBL2_HUMAN | Oxysterol-binding protein-related protein 2 | Homo | <M><N><G><E><E><E><F><F><D><A><V><T><G><F><D><S><D><N><S><S><G><E><F><S><E><A><N><Q><K><V><T><G><M><I><D><L><D><T><S><K><N><N><R><I><G><K><T><G><E><R><P><S><Q><E><N><G><I><Q><K><H><R><T><S><L><P><A><P><M><F><S><R><S><D><F><S><V><W><T><I><L><K><K><C><V><G><L><E><L><S><K><I><T><M><P><I><A><F><N><E><P><L><S><F><L><Q><R><I... | Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane . Binds phosphoinositides, such as phosphatidylinositol-4,5-b... | Q9H1P3 |
Q13889 | TF2H3_HUMAN | TFIIH basal transcription factor complex p34 subunit | Homo | <M><V><S><D><E><D><E><L><N><L><L><V><I><V><V><D><A><N><P><I><W><W><G><K><Q><A><L><K><E><S><Q><F><T><L><S><K><C><I><D><A><V><M><V><L><G><N><S><H><L><F><M><N><R><S><N><K><L><A><V><I><A><S><H><I><Q><E><S><R><F><L><Y><P><G><K><N><G><R><L><G><D><F><F><G><D><P><G><N><P><P><E><F><N><P><S><G><S><K><D><G><K><Y><E><L><L><T><S><A... | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allo... | Q13889 |
P78318 | IGBP1_HUMAN | Renal carcinoma antigen NY-REN-16 | Homo | <M><A><A><E><D><E><L><Q><L><P><R><L><P><E><L><F><E><T><G><R><Q><L><L><D><E><V><E><V><A><T><E><P><A><G><S><R><I><V><Q><E><K><V><F><K><G><L><D><L><L><E><K><A><A><E><M><L><S><Q><L><D><L><F><S><R><N><E><D><L><E><E><I><A><S><T><D><L><K><Y><L><L><V><P><A><F><Q><G><A><L><T><M><K><Q><V><N><P><S><K><R><L><D><H><L><Q><R><A><R><E... | Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.<BOP> | P78318 |
P51800 | CLCKA_HUMAN | ClC-K1 | Homo | <M><E><E><L><V><G><L><R><E><G><F><S><G><D><P><V><T><L><Q><E><L><W><G><P><C><P><H><I><R><R><A><I><Q><G><G><L><E><W><L><K><Q><K><V><F><R><L><G><E><D><W><Y><F><L><M><T><L><G><V><L><M><A><L><V><S><Y><A><M><N><F><A><I><G><C><V><V><R><A><H><Q><W><L><Y><R><E><I><G><D><S><H><L><L><R><Y><L><S><W><T><V><Y><P><V><A><L><V><S><F><S... | Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.<BOP> | P51800 |
O60381 | HBP1_HUMAN | High mobility group box transcription factor 1 | Homo | <M><V><W><E><V><K><T><N><Q><M><P><N><A><V><Q><K><L><L><L><V><M><D><K><R><A><S><G><M><N><D><S><L><E><L><L><Q><C><N><E><N><L><P><S><S><P><G><Y><N><S><C><D><E><H><M><E><L><D><D><L><P><E><L><Q><A><V><Q><S><D><P><T><Q><S><G><M><Y><Q><L><S><S><D><V><S><H><Q><E><Y><P><R><S><S><W><N><Q><N><T><S><D><I><P><E><T><T><Y><R><E><N><E... | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA an... | O60381 |
P01814 | HV270_HUMAN | Ig heavy chain V-II region SESS | Homo | <M><D><I><L><C><S><T><L><L><L><L><T><V><P><S><W><V><L><S><Q><V><T><L><R><E><S><G><P><A><L><V><K><P><T><Q><T><L><T><L><T><C><T><F><S><G><F><S><L><S><T><S><G><M><C><V><S><W><I><R><Q><P><P><G><K><A><L><E><W><L><A><L><I><D><W><D><D><D><K><Y><Y><S><T><S><L><K><T><R><L><T><I><S><K><D><T><S><K><N><Q><V><V><L><T><M><T><N><M><D... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01814 |
P32189 | GLPK_HUMAN | ATP:glycerol 3-phosphotransferase | Homo | <M><A><A><S><K><K><A><V><L><G><P><L><V><G><A><V><D><Q><G><T><S><S><T><R><F><L><V><F><N><S><K><T><A><E><L><L><S><H><H><Q><V><E><I><K><Q><E><F><P><R><E><G><W><V><E><Q><D><P><K><E><I><L><H><S><V><Y><E><C><I><E><K><T><C><E><K><L><G><Q><L><N><I><D><I><S><N><I><K><A><I><G><V><S><N><Q><R><E><T><T><V><V><W><D><K><I><T><G><E><P... | Key enzyme in the regulation of glycerol uptake and metabolism.<BOP> | P32189 |
Q9BQ16 | TICN3_HUMAN | SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3 | Homo | <M><L><K><V><S><A><V><L><C><V><C><A><A><A><W><C><S><Q><S><L><A><A><A><A><A><V><A><A><A><G><G><R><S><D><G><G><N><F><L><D><D><K><Q><W><L><T><T><I><S><Q><Y><D><K><E><V><G><Q><W><N><K><F><R><D><E><V><E><D><D><Y><F><R><T><W><S><P><G><K><P><F><D><Q><A><L><D><P><A><K><D><P><C><L><K><M><K><C><S><R><H><K><V><C><I><A><Q><D><S><Q... | May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.<BOP> | Q9BQ16 |
Q16626 | MEA1_HUMAN | Male-enhanced antigen 1 | Homo | <M><G><P><E><R><H><L><S><G><A><P><A><R><M><A><T><V><V><L><G><G><D><T><M><G><P><E><R><I><F><P><N><Q><T><E><E><L><G><H><Q><G><P><S><E><G><T><G><D><W><S><S><E><E><P><E><E><E><Q><E><E><T><G><S><G><P><A><G><Y><S><Y><Q><P><L><N><Q><D><P><E><Q><E><E><V><E><L><A><P><V><G><D><G><D><V><V><A><D><I><Q><D><R><I><Q><A><L><G><L><H><L... | May play an important role in spermatogenesis and/or testis development.<BOP> | Q16626 |
Q96GM8 | TOE1_HUMAN | Target of EGR1 protein 1 | Homo | <M><A><A><D><S><D><D><G><A><V><S><A><P><A><A><S><D><G><G><V><S><K><S><T><T><S><G><E><E><L><V><V><Q><V><P><V><V><D><V><Q><S><N><N><F><K><E><M><W><P><S><L><L><L><A><I><K><T><A><N><F><V><A><V><D><T><E><L><S><G><L><G><D><R><K><S><L><L><N><Q><C><I><E><E><R><Y><K><A><V><C><H><A><A><R><T><R><S><I><L><S><L><G><L><A><C><F><K><R... | Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing .<BOP> | Q96GM8 |
P16871 | IL7RA_HUMAN | CDw127 | Homo | <M><T><I><L><G><T><T><F><G><M><V><F><S><L><L><Q><V><V><S><G><E><S><G><Y><A><Q><N><G><D><L><E><D><A><E><L><D><D><Y><S><F><S><C><Y><S><Q><L><E><V><N><G><S><Q><H><S><L><T><C><A><F><E><D><P><D><V><N><I><T><N><L><E><F><E><I><C><G><A><L><V><E><V><K><C><L><N><F><R><K><L><Q><E><I><Y><F><I><E><T><K><K><F><L><L><I><G><K><S><N><I... | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).<BOP> | P16871 |
O00400 | ACATN_HUMAN | Solute carrier family 33 member 1 | Homo | <M><S><P><T><I><S><H><K><D><S><S><R><Q><R><R><P><G><N><F><S><H><S><L><D><M><K><S><G><P><L><P><P><G><G><W><D><D><S><H><L><D><S><A><G><R><E><G><D><R><E><A><L><L><G><D><T><G><T><G><D><F><L><K><A><P><Q><S><F><R><A><E><L><S><S><I><L><L><L><L><F><L><Y><V><L><Q><G><I><P><L><G><L><A><G><S><I><P><L><I><L><Q><S><K><N><V><S><Y><T... | Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides . Negatively regulates BMP signaling .<BOP> | O00400 |
Q9NZM5 | NOP53_HUMAN | p60 | Homo | <M><A><A><G><G><S><G><V><G><G><K><R><S><S><K><S><D><A><D><S><G><F><L><G><L><R><P><T><S><V><D><P><A><L><R><R><R><R><R><G><P><R><N><K><K><R><G><W><R><R><L><A><Q><E><P><L><G><L><E><V><D><Q><F><L><E><D><V><R><L><Q><E><R><T><S><G><G><L><L><S><E><A><P><N><E><K><L><F><F><V><D><T><G><S><K><E><K><G><L><T><K><K><R><T><K><V><Q><K... | Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis . In ribosome biogenesis, may also play a role in rRNA transcription . Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis pertur... | Q9NZM5 |
Q9NQF3 | SERHL_HUMAN | Serine hydrolase-like protein | Homo | <M><A><E><N><A><A><P><G><L><I><S><E><L><K><L><A><V><P><W><G><H><I><A><A><K><A><W><G><S><L><Q><G><P><P><V><L><C><L><H><G><W><L><D><N><A><S><S><F><D><R><L><I><P><L><L><P><Q><D><F><Y><Y><V><A><M><D><F><G><G><H><G><L><S><S><H><Y><S><P><G><V><P><Y><Y><L><Q><T><F><V><S><E><I><R><R><V><V><A><A><L><K><W><N><R><F><S><I><L><G><H... | Putative serine hydrolase.<BOP> | Q9NQF3 |
P15509 | CSF2R_HUMAN | CDw116 | Homo | <M><L><L><L><V><T><S><L><L><L><C><E><L><P><H><P><A><F><L><L><I><P><E><K><S><D><L><R><T><V><A><P><A><S><S><L><N><V><R><F><D><S><R><T><M><N><L><S><W><D><C><Q><E><N><T><T><F><S><K><C><F><L><T><D><K><K><N><R><V><V><E><P><R><L><S><N><N><E><C><S><C><T><F><R><E><I><C><L><H><E><G><V><T><F><E><V><H><V><N><T><S><Q><R><G><F><Q><Q... | Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.<BOP> | P15509 |
Q8WUH1 | CHUR_HUMAN | Protein Churchill | Homo | <M><C><G><D><C><V><E><K><E><Y><P><N><R><G><N><T><C><L><E><N><G><S><F><L><L><N><F><T><G><C><A><V><C><S><K><R><D><F><M><L><I><T><N><K><S><L><K><E><E><D><G><E><E><I><V><T><Y><D><H><L><C><K><N><C><H><H><V><I><A><R><H><E><Y><T><F><S><I><M><D><E><F><Q><E><Y><T><M><L><C><L><L><C><G><K><A><E><D><T><I><S><I><L><P><D><D><P><R><Q... | Does not bind DNA by itself.<BOP> | Q8WUH1 |
Q3LHN2 | KR192_HUMAN | Keratin-associated protein 19-2 | Homo | <M><C><Y><G><Y><G><C><G><C><G><S><F><C><R><L><G><Y><G><C><G><Y><E><G><C><R><Y><G><C><G><H><R><G><C><G><D><G><C><C><C><P><S><C><Y><R><R><Y><R><F><T><G><F><Y> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q3LHN2 |
Q9UBE8 | NLK_HUMAN | Protein LAK1 | Homo | <M><S><L><C><G><A><R><A><N><A><K><M><M><A><A><Y><N><G><G><T><S><A><A><A><A><G><H><H><H><H><H><H><H><H><L><P><H><L><P><P><P><H><L><H><H><H><H><H><P><Q><H><H><L><H><P><G><S><A><A><A><V><H><P><V><Q><Q><H><T><S><S><A><A><A><A><A><A><A><A><A><A><A><A><A><M><L><N><P><G><Q><Q><Q><P><Y><F><P><S><P><A><P><G><Q><A><P><G><P><A><A... | Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2. Negative regulator of the canonical Wnt/beta-catenin signaling pathway. Binds to an... | Q9UBE8 |
Q6ZVX9 | PAQR9_HUMAN | Progestin and adipoQ receptor family member IX | Homo | <M><P><R><R><L><Q><P><R><G><A><G><T><K><G><P><P><A><P><A><P><A><A><S><G><A><A><R><N><S><H><S><A><A><S><R><D><P><P><A><S><A><K><P><L><L><R><W><D><E><V><P><D><D><F><V><E><C><F><I><L><S><G><Y><R><R><L><P><C><T><A><Q><E><C><L><A><S><V><L><K><P><T><N><E><T><L><N><F><W><T><H><F><I><P><L><L><L><F><L><S><K><F><C><R><L><F><F><L... | Plasma membrane progesterone (P4) receptor coupled to G proteins . Seems to act through a G(s) mediated pathway . May be involved in regulating rapid P4 signaling in the nervous system . Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone .<BOP> | Q6ZVX9 |
P26371 | KRA59_HUMAN | Ultrahigh sulfur keratin-associated protein 5.9 | Homo | <M><G><C><C><G><C><S><G><G><C><G><S><S><C><G><G><C><D><S><S><C><G><S><C><G><S><G><C><R><G><C><G><P><S><C><C><A><P><V><Y><C><C><K><P><V><C><C><C><V><P><A><C><S><C><S><S><C><G><K><R><G><C><G><S><C><G><G><S><K><G><G><C><G><S><C><G><C><S><Q><C><S><C><C><K><P><C><C><C><S><S><G><C><G><S><S><C><C><Q><C><S><C><C><K><P><Y><C><S... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hai... | P26371 |
P50150 | GBG4_HUMAN | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | Homo | <M><K><E><G><M><S><N><N><S><T><T><S><I><S><Q><A><R><K><A><V><E><Q><L><K><M><E><A><C><M><D><R><V><K><V><S><Q><A><A><A><D><L><L><A><Y><C><E><A><H><V><R><E><D><P><L><I><I><P><V><P><A><S><E><N><P><F><R><E><K><K><F><F><C><T><I><L> | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<BOP> | P50150 |
Q8WVD3 | RN138_HUMAN | RING-type E3 ubiquitin transferase RNF138 | Homo | <M><A><E><D><L><S><A><A><T><S><Y><T><E><D><D><F><Y><C><P><V><C><Q><E><V><L><K><T><P><V><R><T><T><A><C><Q><H><V><F><C><R><K><C><F><L><T><A><M><R><E><S><G><A><H><C><P><L><C><R><G><N><V><T><R><R><E><R><A><C><P><E><R><A><L><D><L><E><N><I><M><R><K><F><S><G><S><C><R><C><C><A><K><Q><I><K><F><Y><R><M><R><H><H><Y><K><S><C><K><K... | E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination . Recruited to sites of double-strand breaks following DNA damage and specifically promotes double-strand break repair via homologous recombination . Two different, non-exclusive, mechanisms have been pro... | Q8WVD3 |
M5A8F1 | SUPYN_HUMAN | endogenous retrovirus group Fb member 1 | Homo | <M><A><C><I><Y><P><T><T><F><Y><T><S><L><P><T><K><S><L><N><M><G><I><S><L><T><T><I><L><I><L><S><V><A><V><L><L><S><T><A><A><P><P><S><C><R><E><C><Y><Q><S><L><H><Y><R><G><E><M><Q><Q><Y><F><T><Y><H><T><H><I><E><R><S><C><Y><G><N><L><I><E><E><C><V><E><S><G><K><S><Y><Y><K><V><K><N><L><G><V><C><G><S><R><N><G><A><I><C><P><R><G><K... | May play a role in trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development. May negatively regulate cell-cell fusion by interacting with SLC1A5, the probable receptor on the cell surface of the fusogenic syncytin-1/ERVW-1.<BOP> | M5A8F1 |
Q8NGX3 | O10T2_HUMAN | Olfactory receptor OR1-3 | Homo | <M><R><G><F><N><K><T><T><V><V><T><Q><F><I><L><V><G><F><S><S><L><G><E><L><Q><L><L><L><F><V><I><F><L><L><L><Y><L><T><I><L><V><A><N><V><T><I><M><A><V><I><R><F><S><W><T><L><H><T><P><M><Y><G><F><L><F><I><L><S><F><S><E><S><C><Y><T><F><V><I><I><P><Q><L><L><V><H><L><L><S><D><T><K><T><I><S><F><M><A><C><A><T><Q><L><F><F><F><L><G... | Odorant receptor.<BOP> | Q8NGX3 |
Q8IYA7 | MKX_HUMAN | Homeobox protein Mohawk | Homo | <M><N><T><I><V><F><N><K><L><S><G><A><V><L><F><E><D><G><G><A><S><E><R><E><R><G><G><R><P><Y><S><G><V><L><D><S><P><H><A><R><P><E><V><G><I><P><D><G><P><P><L><K><D><N><L><G><L><R><H><R><R><T><G><A><R><Q><N><G><G><K><V><R><H><K><R><Q><A><L><Q><D><M><A><R><P><L><K><Q><W><L><Y><K><H><R><D><N><P><Y><P><T><K><T><E><K><I><L><L><A... | May act as a morphogenetic regulator of cell adhesion.<BOP> | Q8IYA7 |
Q3LI61 | KR202_HUMAN | Keratin-associated protein 20-2 | Homo | <M><C><Y><Y><S><N><Y><Y><G><G><L><R><Y><G><Y><G><V><L><G><G><G><Y><G><C><G><C><G><Y><G><H><G><Y><G><G><L><G><C><G><Y><G><R><G><Y><G><G><Y><G><Y><G><C><C><R><P><S><C><Y><G><R><Y><W><S><C><G><F><Y> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q3LI61 |
Q12870 | TCF15_HUMAN | Protein bHLH-EC2 | Homo | <M><A><F><A><L><L><R><P><V><G><A><H><V><L><Y><P><D><V><R><L><L><S><E><D><E><E><N><R><S><E><S><D><A><S><D><Q><S><F><G><C><C><E><G><P><E><A><A><R><R><G><P><G><P><G><G><G><R><R><A><G><G><G><G><G><A><G><P><V><V><V><V><R><Q><R><Q><A><A><N><A><R><E><R><D><R><T><Q><S><V><N><T><A><F><T><A><L><R><T><L><I><P><T><E><P><V><D><R><K... | Early transcription factor that plays a key role in somitogenesis, paraxial mesoderm development and regulation of stem cell pluripotency. Essential for the mesenchymal to epithelial transition associated with somite formation. Required for somite morphogenesis, thereby regulating patterning of the axial skeleton and s... | Q12870 |
Q8WZA6 | OR1E3_HUMAN | Olfactory receptor OR17-7 | Homo | <M><M><K><K><N><Q><T><M><I><S><E><F><L><L><L><G><L><P><I><Q><P><E><Q><Q><N><L><F><Y><A><L><F><L><A><V><Y><L><T><T><L><L><G><N><L><L><V><I><V><L><I><R><L><D><S><H><L><H><M><P><M><Y><L><C><L><S><N><L><S><F><S><D><L><C><F><S><S><V><T><M><P><K><L><L><Q><N><M><Q><S><Q><N><P><S><I><P><F><A><D><C><L><A><Q><M><Y><F><H><L><F><Y... | Odorant receptor.<BOP> | Q8WZA6 |
Q6NXR4 | TTI2_HUMAN | TELO2-interacting protein 2 | Homo | <M><E><L><D><S><A><L><E><A><P><S><Q><E><D><S><N><L><S><E><E><L><S><H><S><A><F><G><Q><A><F><S><K><I><L><H><C><L><A><R><P><E><A><R><R><G><N><V><K><D><A><V><L><K><D><L><G><D><L><I><E><A><T><E><F><D><R><L><F><E><G><T><G><A><R><L><R><G><M><P><E><T><L><G><Q><V><A><K><A><L><E><K><Y><A><A><P><S><K><E><E><E><G><G><G><D><G><H><S... | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (U... | Q6NXR4 |
O00116 | ADAS_HUMAN | Alkylglycerone-phosphate synthase | Homo | <M><A><E><A><A><A><A><A><G><G><T><G><L><G><A><G><A><S><Y><G><S><A><A><D><R><D><R><D><P><D><P><D><R><A><G><R><R><L><R><V><L><S><G><H><L><L><G><R><P><R><E><A><L><S><T><N><E><C><K><A><R><R><A><A><S><A><A><T><A><A><P><T><A><T><P><A><A><Q><E><S><G><T><I><P><K><K><R><Q><E><V><M><K><W><N><G><W><G><Y><N><D><S><K><F><I><F><N><K... | Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis.<BOP> | O00116 |
Q9NZB8 | MOCS1_HUMAN | Molybdenum cofactor biosynthesis protein C | Homo | <M><A><A><R><P><L><S><R><M><L><R><R><L><L><R><S><S><A><R><S><C><S><S><G><A><P><V><T><Q><P><C><P><G><E><S><A><R><A><A><S><E><E><V><S><R><R><R><Q><F><L><R><E><H><A><A><P><F><S><A><F><L><T><D><S><F><G><R><Q><H><S><Y><L><R><I><S><L><T><E><K><C><N><L><R><C><Q><Y><C><M><P><E><E><G><V><P><L><T><P><K><A><N><L><L><T><T><E><E><I... | Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguan... | Q9NZB8 |
Q14653 | IRF3_HUMAN | Interferon regulatory factor 3 | Homo | <M><G><T><P><K><P><R><I><L><P><W><L><V><S><Q><L><D><L><G><Q><L><E><G><V><A><W><V><N><K><S><R><T><R><F><R><I><P><W><K><H><G><L><R><Q><D><A><Q><Q><E><D><F><G><I><F><Q><A><W><A><E><A><T><G><A><Y><V><P><G><R><D><K><P><D><L><P><T><W><K><R><N><F><R><S><A><L><N><R><K><E><G><L><R><L><A><E><D><R><S><K><D><P><H><D><P><H><K><I><Y... | Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses . Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated respo... | Q14653 |
Q8NGK5 | O52M1_HUMAN | Olfactory receptor OR11-11 | Homo | <M><L><T><F><H><N><V><C><S><V><P><S><S><F><W><L><T><G><I><P><G><L><E><S><L><H><V><W><L><S><I><P><F><G><S><M><Y><L><V><A><V><V><G><N><V><T><I><L><A><V><V><K><I><E><R><S><L><H><Q><P><M><Y><F><F><L><C><M><L><A><A><I><D><L><V><L><S><T><S><T><I><P><K><L><L><G><I><F><W><F><G><A><C><D><I><G><L><D><A><C><L><G><Q><M><F><L><I><H... | Odorant receptor.<BOP> | Q8NGK5 |
P49685 | GPR15_HUMAN | Brother of Bonzo | Homo | <M><D><P><E><E><T><S><V><Y><L><D><Y><Y><Y><A><T><S><P><N><S><D><I><R><E><T><H><S><H><V><P><Y><T><S><V><F><L><P><V><F><Y><T><A><V><F><L><T><G><V><L><G><N><L><V><L><M><G><A><L><H><F><K><P><G><S><R><R><L><I><D><I><F><I><I><N><L><A><A><S><D><F><I><F><L><V><T><L><P><L><W><V><D><K><E><A><S><L><G><L><W><R><T><G><S><F><L><C><K... | Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.<BOP> | P49685 |
P06746 | DPOLB_HUMAN | DNA polymerase beta | Homo | <M><S><K><R><K><A><P><Q><E><T><L><N><G><G><I><T><D><M><L><T><E><L><A><N><F><E><K><N><V><S><Q><A><I><H><K><Y><N><A><Y><R><K><A><A><S><V><I><A><K><Y><P><H><K><I><K><S><G><A><E><A><K><K><L><P><G><V><G><T><K><I><A><E><K><I><D><E><F><L><A><T><G><K><L><R><K><L><E><K><I><R><Q><D><D><T><S><S><S><I><N><F><L><T><R><V><S><G><I><G... | Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise... | P06746 |
Q9Y305 | ACOT9_HUMAN | Acyl-CoA thioester hydrolase 9 | Homo | <M><R><R><A><A><L><R><L><C><A><L><G><K><G><Q><L><T><P><G><R><G><L><T><Q><G><P><Q><N><P><K><K><Q><G><I><F><H><I><H><E><V><R><D><K><L><R><E><I><V><G><A><S><T><N><W><R><D><H><V><K><A><M><E><E><R><K><L><L><H><S><F><L><A><K><S><Q><D><G><L><P><P><R><R><M><K><D><S><Y><I><E><V><L><L><P><L><G><S><E><P><E><L><R><E><K><Y><L><T><V... | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs.<BOP> | Q9Y305 |
A8MZ26 | EFCB9_HUMAN | EF-hand calcium-binding domain-containing protein 9 | Homo | <M><R><L><K><Q><G><S><F><L><W><Y><L><Y><L><D><K><I><Y><C><L><L><S><V><R><N><V><K><A><L><A><E><Y><F><H><I><L><D><V><H><G><K><N><T><L><N><D><V><L><F><Y><H><F><L><H><H><V><T><D><L><K><K><A><Q><I><N><I><V><F><D><M><L><D><W><N><A><V><G><E><I><D><F><E><K><F><Y><M><L><V><C><M><L><L><A><H><Q><N><H><L><E><G><Q><F><M><Y><R><H><S... | Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. pH-dependent Ca(2+) sensor required to activate the CatSper channel. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Associates with the CatSper co... | A8MZ26 |
Q9UBQ7 | GRHPR_HUMAN | Glyoxylate reductase/hydroxypyruvate reductase | Homo | <M><R><P><V><R><L><M><K><V><F><V><T><R><R><I><P><A><E><G><R><V><A><L><A><R><A><A><D><C><E><V><E><Q><W><D><S><D><E><P><I><P><A><K><E><L><E><R><G><V><A><G><A><H><G><L><L><C><L><L><S><D><H><V><D><K><R><I><L><D><A><A><G><A><N><L><K><V><I><S><T><M><S><V><G><I><D><H><L><A><L><D><E><I><K><K><R><G><I><R><V><G><Y><T><P><D><V><L... | Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate, oxidizes D-glycerate to hydroxypyruvate.<BOP> | Q9UBQ7 |
Q5XG92 | EST4A_HUMAN | Carboxylesterase 4A | Homo | <M><R><W><I><L><C><W><S><L><T><L><C><L><M><A><Q><T><A><L><G><A><L><H><T><K><R><P><Q><V><V><T><K><Y><G><T><L><Q><G><K><Q><M><H><V><G><K><T><P><I><Q><V><F><L><G><V><P><F><S><R><P><P><L><G><I><L><R><F><A><P><P><E><P><P><E><P><W><K><G><I><R><D><A><T><T><Y><P><P><G><C><L><Q><E><S><W><G><Q><L><A><S><M><Y><V><S><T><R><E><R><Y... | Probable carboxylesterase.<BOP> | Q5XG92 |
P50876 | R144A_HUMAN | Ubiquitin-conjugating enzyme 7-interacting protein 4 | Homo | <M><T><T><T><R><Y><R><P><T><W><D><L><A><L><D><P><L><V><S><C><K><L><C><L><G><E><Y><P><V><E><Q><M><T><T><I><A><Q><C><Q><C><I><F><C><T><L><C><L><K><Q><Y><V><E><L><L><I><K><E><G><L><E><T><A><I><S><C><P><D><A><A><C><P><K><Q><G><H><L><Q><E><N><E><I><E><C><M><V><A><A><E><I><M><Q><R><Y><K><K><L><Q><F><E><R><E><V><L><F><D><P><C... | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.<BOP> | P50876 |
Q16587 | ZNF74_HUMAN | hZNF7 | Homo | <M><E><I><P><A><P><E><P><E><K><T><A><L><S><S><Q><D><P><A><L><S><L><K><E><N><L><E><D><I><S><G><W><G><L><P><E><A><R><S><K><E><S><V><S><F><K><D><V><A><V><D><F><T><Q><E><E><W><G><Q><L><D><S><P><Q><R><A><L><Y><R><D><V><M><L><E><N><Y><Q><N><L><L><A><L><G><P><P><L><H><K><P><D><V><I><S><H><L><E><R><G><E><E><P><W><S><M><Q><R><E... | May play a role in RNA metabolism.<BOP> | Q16587 |
Q02078 | MEF2A_HUMAN | Serum response factor-like protein 1 | Homo | <M><G><R><K><K><I><Q><I><T><R><I><M><D><E><R><N><R><Q><V><T><F><T><K><R><K><F><G><L><M><K><K><A><Y><E><L><S><V><L><C><D><C><E><I><A><L><I><I><F><N><S><S><N><K><L><F><Q><Y><A><S><T><D><M><D><K><V><L><L><K><Y><T><E><Y><N><E><P><H><E><S><R><T><N><S><D><I><V><E><A><L><N><K><K><E><H><R><G><C><D><S><P><D><P><D><T><S><Y><V><L... | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal... | Q02078 |
Q3ZCW2 | LEGL_HUMAN | Lectin galactoside-binding-like protein | Homo | <M><A><G><S><V><A><D><S><D><A><V><V><K><L><D><D><G><H><L><N><N><S><L><S><S><P><V><Q><A><D><V><Y><F><P><R><L><I><V><P><F><C><G><H><I><K><G><G><M><R><P><G><K><K><V><L><V><M><G><I><V><D><L><N><P><E><S><F><A><I><S><L><T><C><G><D><S><E><D><P><P><A><D><V><A><I><E><L><K><A><V><F><T><D><R><Q><L><L><R><N><S><C><I><S><G><E><R><G... | Does not bind lactose, and may not bind carbohydrates.<BOP> | Q3ZCW2 |
Q9Y5I7 | CLD16_HUMAN | Paracellin-1 | Homo | <M><R><D><L><L><Q><Y><I><A><C><F><F><A><F><F><S><A><G><F><L><I><V><A><T><W><T><D><C><W><M><V><N><A><D><D><S><L><E><V><S><T><K><C><R><G><L><W><W><E><C><V><T><N><A><F><D><G><I><R><T><C><D><E><Y><D><S><I><L><A><E><H><P><L><K><L><V><V><T><R><A><L><M><I><T><A><D><I><L><A><G><F><G><F><L><T><L><L><L><G><L><D><C><V><K><F><L><P... | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore ... | Q9Y5I7 |
Q15760 | GPR19_HUMAN | GPR-NGA | Homo | <M><V><F><A><H><R><M><D><N><S><K><P><H><L><I><I><P><T><L><L><V><P><L><Q><N><R><S><C><T><E><T><A><T><P><L><P><S><Q><Y><L><M><E><L><S><E><E><H><S><W><M><S><N><Q><T><D><L><H><Y><V><L><K><P><G><E><V><A><T><A><S><I><F><F><G><I><L><W><L><F><S><I><F><G><N><S><L><V><C><L><V><I><H><R><S><R><R><T><Q><S><T><T><N><Y><F><V><V><S><M... | Orphan receptor.<BOP> | Q15760 |
Q9H2S6 | TNMD_HUMAN | Tendin | Homo | <M><A><K><N><P><P><E><N><C><E><D><C><H><I><L><N><A><E><A><F><K><S><K><K><I><C><K><S><L><K><I><C><G><L><V><F><G><I><L><A><L><T><L><I><V><L><F><W><G><S><K><H><F><W><P><E><V><P><K><K><A><Y><D><M><E><H><T><F><Y><S><N><G><E><K><K><K><I><Y><M><E><I><D><P><V><T><R><T><E><I><F><R><S><G><N><G><T><D><E><T><L><E><V><H><D><F><K><N... | May be an angiogenesis inhibitor.<BOP> | Q9H2S6 |
P01213 | PDYN_HUMAN | Dynorphin B-29 | Homo | <M><A><W><Q><G><L><V><L><A><A><C><L><L><M><F><P><S><T><T><A><D><C><L><S><R><C><S><L><C><A><V><K><T><Q><D><G><P><K><P><I><N><P><L><I><C><S><L><Q><C><Q><A><A><L><L><P><S><E><E><W><E><R><C><Q><S><F><L><S><F><F><T><P><S><T><L><G><L><N><D><K><E><D><L><G><S><K><S><V><G><E><G><P><Y><S><E><L><A><K><L><S><G><S><F><L><K><E><L><E... | Leumorphin has a typical opiod activity and may have anti-apoptotic effect.<BOP> | P01213 |
Q9BX82 | ZN471_HUMAN | EZFIT-related protein 1 | Homo | <M><N><V><E><V><V><K><V><M><P><Q><D><L><V><T><F><K><D><V><A><I><D><F><S><Q><E><E><W><Q><W><M><N><P><A><Q><K><R><L><Y><R><S><M><M><L><E><N><Y><Q><S><L><V><S><L><G><L><C><I><S><K><P><Y><V><I><S><L><L><E><Q><G><R><E><P><W><E><M><T><S><E><M><T><R><S><P><F><S><D><W><E><S><I><Y><V><T><Q><E><L><P><L><K><Q><F><M><Y><D><D><A><C... | May be involved in transcriptional regulation.<BOP> | Q9BX82 |
Q96L92 | SNX27_HUMAN | Sorting nexin-27 | Homo | <M><A><D><E><D><G><E><G><I><H><P><S><A><P><H><R><N><G><G><G><G><G><G><G><G><S><G><L><H><C><A><G><N><G><G><G><G><G><G><G><P><R><V><V><R><I><V><K><S><E><S><G><Y><G><F><N><V><R><G><Q><V><S><E><G><G><Q><L><R><S><I><N><G><E><L><Y><A><P><L><Q><H><V><S><A><V><L><P><G><G><A><A><D><R><A><G><V><R><K><G><D><R><I><L><E><V><N><H><V... | Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in... | Q96L92 |
Q8NA42 | ZN383_HUMAN | Zinc finger protein 383 | Homo | <M><A><E><G><S><V><M><F><S><D><V><S><I><D><F><S><Q><E><E><W><D><C><L><D><P><V><Q><R><D><L><Y><R><D><V><M><L><E><N><Y><G><N><L><V><S><M><G><L><Y><T><P><K><P><Q><V><I><S><L><L><E><Q><G><K><E><P><W><M><V><G><R><E><L><T><R><G><L><C><S><D><L><E><S><M><C><E><T><K><L><L><S><L><K><K><E><V><Y><E><I><E><L><C><Q><R><E><I><M><G><L... | May function as a transcriptional repressor, suppressing transcriptional activities mediated by MAPK signaling pathways.<BOP> | Q8NA42 |
Q8IUB5 | WFD13_HUMAN | WAP four-disulfide core domain protein 13 | Homo | <M><K><P><V><L><P><L><Q><F><L><V><V><F><C><L><A><L><Q><L><V><P><G><S><P><K><Q><R><V><L><K><Y><I><L><E><P><P><P><C><I><S><A><P><E><N><C><T><H><L><C><T><M><Q><E><D><C><E><K><G><F><Q><C><C><S><S><F><C><G><I><V><C><S><S><E><T><F><Q><K><R><N><R><I><K><H><K><G><S><E><V><I><M><P><A><N> | Putative acid-stable proteinase inhibitor.<BOP> | Q8IUB5 |
P17050 | NAGAB_HUMAN | Alpha-galactosidase B | Homo | <M><L><L><K><T><V><L><L><L><G><H><V><A><Q><V><L><M><L><D><N><G><L><L><Q><T><P><P><M><G><W><L><A><W><E><R><F><R><C><N><I><N><C><D><E><D><P><K><N><C><I><S><E><Q><L><F><M><E><M><A><D><R><M><A><Q><D><G><W><R><D><M><G><Y><T><Y><L><N><I><D><D><C><W><I><G><G><R><D><A><S><G><R><L><M><P><D><P><K><R><F><P><H><G><I><P><F><L><A><D... | Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids.<BOP> | P17050 |
Q99541 | PLIN2_HUMAN | Adipose differentiation-related protein | Homo | <M><A><S><V><A><V><D><P><Q><P><S><V><V><T><R><V><V><N><L><P><L><V><S><S><T><Y><D><L><M><S><S><A><Y><L><S><T><K><D><Q><Y><P><Y><L><K><S><V><C><E><M><A><E><N><G><V><K><T><I><T><S><V><A><M><T><S><A><L><P><I><I><Q><K><L><E><P><Q><I><A><V><A><N><T><Y><A><C><K><G><L><D><R><I><E><E><R><L><P><I><L><N><Q><P><S><T><Q><I><V><A><N... | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.<BOP> | Q99541 |
Q14108 | SCRB2_HUMAN | Scavenger receptor class B member 2 | Homo | <M><G><R><C><C><F><Y><T><A><G><T><L><S><L><L><L><L><V><T><S><V><T><L><L><V><A><R><V><F><Q><K><A><V><D><Q><S><I><E><K><K><I><V><L><R><N><G><T><E><A><F><D><S><W><E><K><P><P><L><P><V><Y><T><Q><F><Y><F><F><N><V><T><N><P><E><E><I><L><R><G><E><T><P><R><V><E><E><V><G><P><Y><T><Y><R><E><L><R><N><K><A><N><I><Q><F><G><D><N><G><T... | (Microbial infection) Acts as a receptor for enterovirus 71.<BOP> | Q14108 |
O14793 | GDF8_HUMAN | Myostatin | Homo | <M><Q><K><L><Q><L><C><V><Y><I><Y><L><F><M><L><I><V><A><G><P><V><D><L><N><E><N><S><E><Q><K><E><N><V><E><K><E><G><L><C><N><A><C><T><W><R><Q><N><T><K><S><S><R><I><E><A><I><K><I><Q><I><L><S><K><L><R><L><E><T><A><P><N><I><S><K><D><V><I><R><Q><L><L><P><K><A><P><P><L><R><E><L><I><D><Q><Y><D><V><Q><R><D><D><S><S><D><G><S><L><E... | Acts specifically as a negative regulator of skeletal muscle growth.<BOP> | O14793 |
Q9UJX0 | OSGI1_HUMAN | Pregnancy-induced growth inhibitor OKL38 | Homo | <M><S><S><S><R><K><D><H><L><G><A><S><S><S><E><P><L><P><V><I><I><V><G><N><G><P><S><G><I><C><L><S><Y><L><L><S><G><Y><T><P><Y><T><K><P><D><A><I><H><P><H><P><L><L><Q><R><K><L><T><E><A><P><G><V><S><I><L><D><Q><D><L><D><Y><L><S><E><G><L><E><G><R><S><Q><S><P><V><A><L><L><F><D><A><L><L><R><P><D><T><D><F><G><G><N><M><K><S><V><L... | Regulates the differentiation and proliferation through the regulation of cell death.<BOP> | Q9UJX0 |
Q6UX65 | DRAM2_HUMAN | Transmembrane protein 77 | Homo | <M><W><W><F><Q><Q><G><L><S><F><L><P><S><A><L><V><I><W><T><S><A><A><F><I><F><S><Y><I><T><A><V><T><L><H><H><I><D><P><A><L><P><Y><I><S><D><T><G><T><V><A><P><E><K><C><L><F><G><A><M><L><N><I><A><A><V><L><C><I><A><T><I><Y><V><R><Y><K><Q><V><H><A><L><S><P><E><E><N><V><I><I><K><L><N><K><A><G><L><V><L><G><I><L><S><C><L><G><L><S... | Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1.<BOP> | Q6UX65 |
Q13352 | CENPR_HUMAN | Nuclear receptor-interacting factor 3 | Homo | <M><P><V><K><R><S><L><K><L><D><G><L><L><E><E><N><S><F><D><P><S><K><I><T><R><K><K><S><V><I><T><Y><S><P><T><T><G><T><C><Q><M><S><L><F><A><S><P><T><S><S><E><E><Q><K><H><R><N><G><L><S><N><E><K><R><K><K><L><N><H><P><S><L><T><E><S><K><E><S><T><T><K><D><N><D><E><F><M><M><L><L><S><K><V><E><K><L><S><E><E><I><M><E><I><M><Q><N><L... | Transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic ac... | Q13352 |
Q5T1C6 | THEM4_HUMAN | Thioesterase superfamily member 4 | Homo | <M><L><R><S><C><A><A><R><L><R><T><L><G><A><L><C><L><P><P><V><G><R><R><L><P><G><S><E><P><R><P><E><L><R><S><F><S><S><E><E><V><I><L><K><D><C><S><V><P><N><P><S><W><N><K><D><L><R><L><L><F><D><Q><F><M><K><K><C><E><D><G><S><W><K><R><L><P><S><Y><K><R><T><P><T><E><W><I><Q><D><F><K><T><H><F><L><D><P><K><L><M><K><E><E><Q><M><S><Q... | Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and ... | Q5T1C6 |
Q96LL3 | FIMP_HUMAN | Fertilization-influencing membrane protein | Homo | <M><G><A><G><V><G><V><A><G><C><T><R><G><H><R><N><W><V><P><S><Q><L><P><P><R><E><I><K><A><G><V><S><L><A><V><V><T><E><F><A><W><V><L><A><P><R><P><K><R><A><T><A><S><A><L><G><T><E><S><P><R><F><L><D><R><P><D><F><F><D><Y><P><D><S><D><Q><A><R><L><L><A><V><A><Q><F><I><G><E><K><P><I><V><F><I><N><S><G><S><S><P><G><L><F><H><H><I><L... | May play a role in sperm-oocyte fusion during fertilization.<BOP> | Q96LL3 |
P0C7M3 | SFTA3_HUMAN | Surfactant-associated protein H | Homo | <M><R><A><G><F><S><D><F><Q><L><I><R><D><Q><V><L><F><L><Q><D><Q><A><Q><R><L><T><E><W><L><Q><L><S><G><F><E><N><P><V><S><E><S><T><T><L><C><L><R><E><R><E><K><R><I><P><T><C><V><A><V><C><V><P><S><P><G><T><V><H><T><A><L><L><H><P><T><T><L><S><Q><S><R><S><S><S><E><A><K><M><L><I><I><H><T><A> | Putative surfactant protein. May be involved in wound healing and in the reduction of the surface tension at the ocular surface.<BOP> | P0C7M3 |
A6NK75 | ZNF98_HUMAN | Zinc finger protein F7175 | Homo | <M><P><G><P><L><G><S><L><E><M><G><V><L><T><F><R><D><V><A><L><E><F><S><L><E><E><W><Q><C><L><D><T><A><Q><Q><N><L><Y><R><N><V><M><L><E><N><Y><R><N><L><V><F><V><G><I><A><A><S><K><P><D><L><I><T><C><L><E><Q><G><K><E><P><W><N><V><K><R><H><E><M><V><T><E><P><P><V><V><Y><S><Y><F><A><Q><D><L><W><P><K><Q><G><K><K><N><Y><F><Q><K><V... | May be involved in transcriptional regulation.<BOP> | A6NK75 |
Q8NGF1 | O52R1_HUMAN | Olfactory receptor OR11-22 | Homo | <M><V><L><A><S><G><N><S><S><S><H><P><V><S><F><I><L><L><G><I><P><G><L><E><S><F><Q><L><W><I><A><F><P><F><C><A><T><Y><A><V><A><V><V><G><N><I><T><L><L><H><V><I><R><I><D><H><T><L><H><E><P><M><Y><L><F><L><A><M><L><A><I><T><D><L><V><L><S><S><S><T><Q><P><K><M><L><A><I><F><W><F><H><A><H><E><I><Q><Y><H><A><C><L><I><Q><V><F><F><I... | Odorant receptor.<BOP> | Q8NGF1 |
P30048 | PRDX3_HUMAN | Thioredoxin-dependent peroxiredoxin 3 | Homo | <M><A><A><A><V><G><R><L><L><R><A><S><V><A><R><H><V><S><A><I><P><W><G><I><S><A><T><A><A><L><R><P><A><A><C><G><R><T><S><L><T><N><L><L><C><S><G><S><S><Q><A><K><L><F><S><T><S><S><S><C><H><A><P><A><V><T><Q><H><A><P><Y><F><K><G><T><A><V><V><N><G><E><F><K><D><L><S><L><D><D><F><K><G><K><Y><L><V><L><F><F><Y><P><L><D><F><T><F><V... | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides . Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol .<BOP> | P30048 |
Q9NRA2 | S17A5_HUMAN | Vesicular H(+)/Aspartate-glutamate cotransporter | Homo | <M><R><S><P><V><R><D><L><A><R><N><D><G><E><E><S><T><D><R><T><P><L><L><P><G><A><P><R><A><E><A><A><P><V><C><C><S><A><R><Y><N><L><A><I><L><A><F><F><G><F><F><I><V><Y><A><L><R><V><N><L><S><V><A><L><V><D><M><V><D><S><N><T><T><L><E><D><N><R><T><S><K><A><C><P><E><H><S><A><P><I><K><V><H><H><N><Q><T><G><K><K><Y><Q><W><D><A><E><T... | Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential-dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functio... | Q9NRA2 |
P01008 | ANT3_HUMAN | Serpin C1 | Homo | <M><Y><S><N><V><I><G><T><V><T><S><G><K><R><K><V><Y><L><L><S><L><L><L><I><G><F><W><D><C><V><T><C><H><G><S><P><V><D><I><C><T><A><K><P><R><D><I><P><M><N><P><M><C><I><Y><R><S><P><E><K><K><A><T><E><D><E><G><S><E><Q><K><I><P><E><A><T><N><R><R><V><W><E><L><S><K><A><N><S><R><F><A><T><T><F><Y><Q><H><L><A><D><S><K><N><D><N><D><N... | Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade . AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa . Its inhibitory activity is greatly enhanced in the presence of heparin.<BOP> | P01008 |
P43378 | PTN9_HUMAN | Protein-tyrosine phosphatase MEG2 | Homo | <M><E><P><A><T><A><P><R><P><D><M><A><P><E><L><T><P><E><E><E><Q><A><T><K><Q><F><L><E><E><I><N><K><W><T><V><Q><Y><N><V><S><P><L><S><W><N><V><A><V><K><F><L><M><A><R><K><F><D><V><L><R><A><I><E><L><F><H><S><Y><R><E><T><R><R><K><E><G><I><V><K><L><K><P><H><E><E><P><L><R><S><E><I><L><S><G><K><F><T><I><L><N><V><R><D><P><T><G><A... | Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.<BOP> | P43378 |
O60729 | CC14B_HUMAN | CDC14 cell division cycle 14 homolog B | Homo | <M><K><R><K><S><E><R><R><S><S><W><A><A><A><P><P><C><S><R><R><C><S><S><T><S><P><G><V><K><K><I><R><S><S><T><Q><Q><D><P><R><R><R><D><P><Q><D><D><V><Y><L><D><I><T><D><R><L><C><F><A><I><L><Y><S><R><P><K><S><A><S><N><V><H><Y><F><S><I><D><N><E><L><E><Y><E><N><F><Y><A><D><F><G><P><L><N><L><A><M><V><Y><R><Y><C><C><K><I><N><K><K... | Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosph... | O60729 |
Q99661 | KIF2C_HUMAN | Mitotic centromere-associated kinesin | Homo | <M><A><M><D><S><S><L><Q><A><R><L><F><P><G><L><A><I><K><I><Q><R><S><N><G><L><I><H><S><A><N><V><R><T><V><N><L><E><K><S><C><V><S><V><E><W><A><E><G><G><A><T><K><G><K><E><I><D><F><D><D><V><A><A><I><N><P><E><L><L><Q><L><L><P><L><H><P><K><D><N><L><P><L><Q><E><N><V><T><I><Q><K><Q><K><R><R><S><V><N><S><K><I><P><A><P><K><E><S><L... | In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells . Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis . Plays a role in chromosome congression and is required for the lateral to end-on conversion of ... | Q99661 |
Q9UII6 | DS13B_HUMAN | Testis- and skeletal-muscle-specific DSP | Homo | <M><D><S><L><Q><K><Q><D><L><R><R><P><K><I><H><G><A><V><Q><A><S><P><Y><Q><P><P><T><L><A><S><L><Q><R><L><L><W><V><R><Q><A><A><T><L><N><H><I><D><E><V><W><P><S><L><F><L><G><D><A><Y><A><A><R><D><K><S><K><L><I><Q><L><G><I><T><H><V><V><N><A><A><A><G><K><F><Q><V><D><T><G><A><K><F><Y><R><G><M><S><L><E><Y><Y><G><I><E><A><D><D><N... | Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro . Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro .<BOP> | Q9UII6 |
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