accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q6AW86 | Z324B_HUMAN | Zinc finger protein 324B | Homo | <M><T><F><E><D><V><A><V><Y><F><S><Q><E><E><W><G><L><L><D><T><A><Q><R><A><L><Y><R><H><V><M><L><E><N><F><T><L><V><T><S><L><G><L><S><T><S><R><P><R><V><V><I><Q><L><E><R><G><E><E><P><W><V><P><S><G><K><D><M><T><L><A><R><N><T><Y><G><R><L><N><S><G><S><W><S><L><T><E><D><R><D><V><S><G><E><W><P><R><A><F><P><D><T><P><P><G><M><T><T... | May be involved in transcriptional regulation.<BOP> | Q6AW86 |
Q14206 | RCAN2_HUMAN | Thyroid hormone-responsive protein ZAKI-4 | Homo | <M><P><A><P><S><M><D><C><D><V><S><T><L><V><A><C><V><V><D><V><E><V><F><T><N><Q><E><V><K><E><K><F><E><G><L><F><R><T><Y><D><D><C><V><T><F><Q><L><F><K><S><F><R><R><V><R><I><N><F><S><N><P><K><S><A><A><R><A><R><I><E><L><H><E><T><Q><F><R><G><K><K><L><K><L><Y><F><A><Q><V><Q><T><P><E><T><D><G><D><K><L><H><L><A><P><P><Q><P><A><K... | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.<BOP> | Q14206 |
P41586 | PACR_HUMAN | Pituitary adenylate cyclase-activating polypeptide type I receptor | Homo | <M><A><G><V><V><H><V><S><L><A><A><L><L><L><L><P><M><A><P><A><M><H><S><D><C><I><F><K><K><E><Q><A><M><C><L><E><K><I><Q><R><A><N><E><L><M><G><F><N><D><S><S><P><G><C><P><G><M><W><D><N><I><T><C><W><K><P><A><H><V><G><E><M><V><L><V><S><C><P><E><L><F><R><I><F><N><P><D><Q><V><W><E><T><E><T><I><G><E><S><D><F><G><D><S><N><S><L><D... | This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. C... | P41586 |
P15153 | RAC2_HUMAN | p21-Rac2 | Homo | <M><Q><A><I><K><C><V><V><V><G><D><G><A><V><G><K><T><C><L><L><I><S><Y><T><T><N><A><F><P><G><E><Y><I><P><T><V><F><D><N><Y><S><A><N><V><M><V><D><S><K><P><V><N><L><G><L><W><D><T><A><G><Q><E><D><Y><D><R><L><R><P><L><S><Y><P><Q><T><D><V><F><L><I><C><F><S><L><V><S><P><A><S><Y><E><N><V><R><A><K><W><F><P><E><V><R><H><H><C><P><S... | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of ... | P15153 |
Q8WYN0 | ATG4A_HUMAN | Autophagy-related protein 4 homolog A | Homo | <M><E><S><V><L><S><K><Y><E><D><Q><I><T><I><F><T><D><Y><L><E><E><Y><P><D><T><D><E><L><V><W><I><L><G><K><Q><H><L><L><K><T><E><K><S><K><L><L><S><D><I><S><A><R><L><W><F><T><Y><R><R><K><F><S><P><I><G><G><T><G><P><S><S><D><A><G><W><G><C><M><L><R><C><G><Q><M><M><L><A><Q><A><L><I><C><R><H><L><G><R><D><W><S><W><E><K><Q><K><E><Q... | Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins . The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine . Exposure of t... | Q8WYN0 |
Q04118 | PRB3_HUMAN | Proline-rich protein G1 | Homo | <M><L><L><I><L><L><S><V><A><L><L><A><L><S><S><A><Q><S><L><N><E><D><V><S><Q><E><E><S><P><S><V><I><S><G><K><P><E><G><R><R><P><Q><G><G><N><Q><P><Q><R><T><P><P><P><P><G><K><P><E><G><R><P><P><Q><G><G><N><Q><S><Q><G><P><P><P><R><P><G><K><P><E><G><P><P><P><Q><G><G><N><Q><S><Q><G><P><P><P><R><P><G><K><P><E><G><Q><P><P><Q><G><G... | Acts as a receptor for the Gram-negative bacterium F.nucleatum.<BOP> | Q04118 |
Q32MQ0 | ZN750_HUMAN | Zinc finger protein 750 | Homo | <M><S><L><L><K><E><R><K><P><K><K><P><H><Y><I><P><R><P><P><G><K><P><F><K><Y><K><C><F><Q><C><P><F><T><C><N><E><K><S><H><L><F><N><H><M><K><Y><G><L><C><K><N><S><I><T><L><V><S><E><Q><D><R><V><P><K><C><P><K><S><N><S><L><D><P><K><Q><T><N><Q><P><D><A><T><A><K><P><A><S><S><K><S><V><A><N><G><L><S><A><F><D><S><K><L><Q><H><S><S><A... | Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression.<BOP> | Q32MQ0 |
Q05084 | ICA69_HUMAN | Islet cell autoantigen p69 | Homo | <M><S><G><H><K><C><S><Y><P><W><D><L><Q><D><R><Y><A><Q><D><K><S><V><V><N><K><M><Q><Q><K><Y><W><E><T><K><Q><A><F><I><K><A><T><G><K><K><E><D><E><H><V><V><A><S><D><A><D><L><D><A><K><L><E><L><F><H><S><I><Q><R><T><C><L><D><L><S><K><A><I><V><L><Y><Q><K><R><I><C><F><L><S><Q><E><E><N><E><L><G><K><F><L><R><S><Q><G><F><Q><D><K><T... | May play a role in neurotransmitter secretion.<BOP> | Q05084 |
P01270 | PTHY_HUMAN | Parathyrin | Homo | <M><I><P><A><K><D><M><A><K><V><M><I><V><M><L><A><I><C><F><L><T><K><S><D><G><K><S><V><K><K><R><S><V><S><E><I><Q><L><M><H><N><L><G><K><H><L><N><S><M><E><R><V><E><W><L><R><K><K><L><Q><D><V><H><N><F><V><A><L><G><A><P><L><A><P><R><D><A><G><S><Q><R><P><R><K><K><E><D><N><V><L><V><E><S><H><E><K><S><L><G><E><A><D><K><A><D><V><N... | PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.<BOP> | P01270 |
P48307 | TFPI2_HUMAN | Placental protein 5 | Homo | <M><D><P><A><R><P><L><G><L><S><I><L><L><L><F><L><T><E><A><A><L><G><D><A><A><Q><E><P><T><G><N><N><A><E><I><C><L><L><P><L><D><Y><G><P><C><R><A><L><L><L><R><Y><Y><Y><D><R><Y><T><Q><S><C><R><Q><F><L><Y><G><G><C><E><G><N><A><N><N><F><Y><T><W><E><A><C><D><D><A><C><W><R><I><E><K><V><P><K><V><C><R><L><Q><V><S><V><D><D><Q><C><E... | May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.<BOP> | P48307 |
Q5QGT7 | RTP2_HUMAN | 3CxxC-type zinc finger protein 2 | Homo | <M><C><T><S><L><T><T><C><E><W><K><K><V><F><Y><E><K><M><E><V><A><K><P><A><D><S><W><E><L><I><I><D><P><N><L><K><P><S><E><L><A><P><G><W><K><Q><Y><L><E><Q><H><A><S><G><R><F><H><C><S><W><C><W><H><T><W><Q><S><A><H><V><V><I><L><F><H><M><F><L><D><R><A><Q><R><A><G><S><V><R><M><R><V><F><K><Q><L><C><Y><E><C><G><T><A><R><L><D><E><S... | Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs.<BOP> | Q5QGT7 |
Q8N9W5 | DAAF3_HUMAN | Dynein axonemal assembly factor 3 | Homo | <M><T><T><P><A><G><S><G><S><G><F><G><S><V><S><W><W><G><L><S><P><A><L><D><L><Q><A><E><S><P><P><V><D><P><D><S><Q><A><D><T><V><H><S><N><P><E><L><D><V><L><L><L><G><S><V><D><G><R><H><L><L><R><T><L><S><R><A><K><F><W><P><R><R><R><F><N><F><F><V><L><E><N><N><L><E><A><V><A><R><H><M><L><I><F><S><L><A><L><E><E><P><E><K><M><G><L><Q... | Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.<BOP> | Q8N9W5 |
Q9Y575 | ASB3_HUMAN | Ankyrin repeat and SOCS box protein 3 | Homo | <M><D><F><T><E><A><Y><A><D><T><C><S><T><V><G><L><A><A><R><E><G><N><V><K><V><L><R><K><L><L><K><K><G><R><S><V><D><V><A><D><N><R><G><W><M><P><I><H><E><A><A><Y><H><N><S><V><E><C><L><Q><M><L><I><N><A><D><S><S><E><N><Y><I><K><M><K><T><F><E><G><F><C><A><L><H><L><A><A><S><Q><G><H><W><K><I><V><Q><I><L><L><E><A><G><A><D><P><N><A... | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B.<BOP> | Q9Y575 |
Q15554 | TERF2_HUMAN | Telomeric DNA-binding protein | Homo | <M><A><A><G><A><G><T><A><G><P><A><S><G><P><G><V><V><R><D><P><A><A><S><Q><P><R><K><R><P><G><R><E><G><G><E><G><A><R><R><S><D><T><M><A><G><G><G><G><S><S><D><G><S><G><R><A><A><G><R><R><A><S><R><S><S><G><R><A><R><R><G><R><H><E><P><G><L><G><G><P><A><E><R><G><A><G><E><A><R><L><E><E><A><V><N><R><W><V><L><K><F><Y><F><H><E><A><L... | Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin c... | Q15554 |
P08246 | ELNE_HUMAN | PMN elastase | Homo | <M><T><L><G><R><R><L><A><C><L><F><L><A><C><V><L><P><A><L><L><L><G><G><T><A><L><A><S><E><I><V><G><G><R><R><A><R><P><H><A><W><P><F><M><V><S><L><Q><L><R><G><G><H><F><C><G><A><T><L><I><A><P><N><F><V><M><S><A><A><H><C><V><A><N><V><N><V><R><A><V><R><V><V><L><G><A><H><N><L><S><R><R><E><P><T><R><Q><V><F><A><V><Q><R><I><F><E><N... | Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis . Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae .<BOP> | P08246 |
Q5T9C2 | F102A_HUMAN | Early estrogen-induced gene 1 protein | Homo | <M><A><F><L><M><K><K><K><K><F><K><F><Q><T><T><F><T><L><E><E><L><T><A><V><P><F><V><N><G><V><L><F><C><K><V><R><L><L><D><G><G><D><F><V><S><L><S><S><R><E><E><V><Q><E><N><C><V><R><W><R><K><R><F><T><F><V><C><K><M><S><A><N><P><A><T><G><L><L><D><P><C><V><F><R><V><S><V><R><K><E><L><K><G><G><K><A><Y><S><K><L><G><F><A><D><L><N><L... | May play a role in estrogen action.<BOP> | Q5T9C2 |
B2RN74 | O11HC_HUMAN | Olfactory receptor 11H12 | Homo | <M><C><P><L><T><L><Q><V><T><G><L><M><N><V><S><E><P><N><S><S><F><A><F><V><N><E><F><I><L><Q><G><F><T><C><E><W><T><I><Q><I><F><L><F><S><L><F><T><T><T><Y><A><L><T><I><T><G><N><G><A><I><A><F><V><L><W><C><D><W><R><L><H><T><P><M><Y><M><F><L><G><N><F><S><F><L><E><I><W><Y><V><S><S><T><V><P><K><M><L><V><N><F><L><S><E><K><K><N><I... | Odorant receptor.<BOP> | B2RN74 |
Q92733 | PRCC_HUMAN | Papillary renal cell carcinoma translocation-associated gene protein | Homo | <M><S><L><V><A><Y><A><S><S><D><E><S><E><P><D><E><A><E><P><E><P><E><E><E><E><A><V><A><P><T><S><G><P><A><L><G><G><L><F><A><S><L><P><A><P><K><G><P><A><L><L><P><P><P><P><Q><M><L><A><P><A><F><P><P><P><L><L><L><P><P><P><T><G><D><P><R><L><Q><P><P><P><P><L><P><F><G><L><G><G><F><P><P><P><P><G><V><S><P><A><E><A><A><G><V><G><E><G... | May regulate cell cycle progression through interaction with MAD2L2.<BOP> | Q92733 |
Q8N6H7 | ARFG2_HUMAN | Zinc finger protein 289 | Homo | <M><A><A><E><P><N><K><T><E><I><Q><T><L><F><K><R><L><R><A><V><P><T><N><K><A><C><F><D><C><G><A><K><N><P><S><W><A><S><I><T><Y><G><V><F><L><C><I><D><C><S><G><V><H><R><S><L><G><V><H><L><S><F><I><R><S><T><E><L><D><S><N><W><N><W><F><Q><L><R><C><M><Q><V><G><G><N><A><N><A><T><A><F><F><R><Q><H><G><C><T><A><N><D><A><N><T><K><Y><N... | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.<BOP> | Q8N6H7 |
A0A1B0GX78 | TVBL5_HUMAN | T cell receptor beta variable 12-5 | Homo | <M><A><T><R><L><L><C><C><V><V><L><C><L><L><G><E><E><L><I><D><A><R><V><T><Q><T><P><R><H><K><V><T><E><M><G><Q><E><V><T><M><R><C><Q><P><I><L><G><H><N><T><V><F><W><Y><R><Q><T><M><M><Q><G><L><E><L><L><A><Y><F><R><N><R><A><P><L><D><D><S><G><M><P><K><D><R><F><S><A><E><M><P><D><A><T><L><A><T><L><K><I><Q><P><S><E><P><R><D><S><A... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A1B0GX78 |
P21291 | CSRP1_HUMAN | Epididymis luminal protein 141 | Homo | <M><P><N><W><G><G><G><K><K><C><G><V><C><Q><K><T><V><Y><F><A><E><E><V><Q><C><E><G><N><S><F><H><K><S><C><F><L><C><M><V><C><K><K><N><L><D><S><T><T><V><A><V><H><G><E><E><I><Y><C><K><S><C><Y><G><K><K><Y><G><P><K><G><Y><G><Y><G><Q><G><A><G><T><L><S><T><D><K><G><E><S><L><G><I><K><H><E><E><A><P><G><H><R><P><T><T><N><P><N><A><S... | Could play a role in neuronal development.<BOP> | P21291 |
O60760 | HPGDS_HUMAN | Prostaglandin-H2 D-isomerase | Homo | <M><P><N><Y><K><L><T><Y><F><N><M><R><G><R><A><E><I><I><R><Y><I><F><A><Y><L><D><I><Q><Y><E><D><H><R><I><E><Q><A><D><W><P><E><I><K><S><T><L><P><F><G><K><I><P><I><L><E><V><D><G><L><T><L><H><Q><S><L><A><I><A><R><Y><L><T><K><N><T><D><L><A><G><N><T><E><M><E><Q><C><H><V><D><A><I><V><D><T><L><D><D><F><M><S><C><F><P><W><A><E><K... | Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxi... | O60760 |
Q96E39 | RMXL1_HUMAN | Heterogeneous nuclear ribonucleoprotein G-like 1 | Homo | <M><V><E><A><D><R><P><G><K><L><F><I><G><G><L><N><T><E><T><N><E><K><A><L><E><T><V><F><G><K><Y><G><R><I><V><E><V><L><L><I><K><D><R><E><T><N><K><S><R><G><F><A><F><V><T><F><E><S><P><A><D><A><K><D><A><A><R><D><M><N><G><K><S><L><D><G><K><A><I><K><V><E><Q><A><T><K><P><S><F><E><R><G><R><H><G><P><P><P><P><P><R><S><R><G><P><P><R... | RNA-binding protein which may be involved in pre-mRNA splicing.<BOP> | Q96E39 |
Q68DK7 | MSL1_HUMAN | Male-specific lethal-1 homolog 1 | Homo | <M><T><M><R><S><A><V><F><K><A><A><A><A><P><A><G><G><N><P><E><Q><R><L><D><Y><E><R><A><A><A><L><G><G><P><E><D><E><P><G><A><A><E><A><H><F><L><P><R><H><R><K><L><K><E><P><G><P><P><L><A><S><S><Q><G><G><S><P><A><P><S><P><A><G><C><G><G><K><G><R><G><L><L><L><P><A><G><A><A><P><G><Q><Q><E><E><S><W><G><G><S><V><P><L><P><C><P><P><P... | Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac) which is implicated in the formation of higher-order chromatin structure . Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub) . ... | Q68DK7 |
A6NF83 | NUPR2_HUMAN | Nuclear transcriptional regulator protein 2 | Homo | <M><E><A><P><A><E><R><A><L><P><R><L><Q><A><L><A><R><P><P><P><P><I><S><Y><E><E><E><L><Y><D><C><L><D><Y><Y><Y><L><R><D><F><P><A><C><G><A><G><R><S><K><G><R><T><R><R><E><Q><A><L><R><T><N><W><P><A><P><G><G><H><E><R><K><V><A><Q><K><L><L><N><G><Q><R><K><R><R><Q><R><Q><L><H><P><K><M><R><T><R><L><T> | Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells . Involved in the G1 cell cycle arrest, and in a decrease in cell viability and cell proliferation . Plays a role as a negative regulator of the protumoral factor NUPR1 .<BOP> | A6NF83 |
Q11130 | FUT7_HUMAN | Selectin ligand synthase | Homo | <M><N><N><A><G><H><G><P><T><R><R><L><R><G><L><G><V><L><A><G><V><A><L><L><A><A><L><W><L><L><W><L><L><G><S><A><P><R><G><T><P><A><P><Q><P><T><I><T><I><L><V><W><H><W><P><F><T><D><Q><P><P><E><L><P><S><D><T><C><T><R><Y><G><I><A><R><C><H><L><S><A><N><R><S><L><L><A><S><A><D><A><V><V><F><H><H><R><E><L><Q><T><R><R><S><H><L><P><L... | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein or a glycolipid-linked sialopolylactosamines chain through an alpha-1,3 glycosidic linkage and participates in the final fucosylation st... | Q11130 |
Q8NGS8 | O13C5_HUMAN | Olfactory receptor OR9-11 | Homo | <M><E><W><E><N><H><T><I><L><V><E><F><F><L><K><G><L><S><G><H><P><R><L><E><L><L><F><F><V><L><I><F><I><M><Y><V><V><I><L><L><G><N><G><T><L><I><L><I><S><I><L><D><P><H><L><H><T><P><M><Y><F><F><L><G><N><L><S><F><L><D><I><C><Y><T><T><T><S><I><P><S><T><L><V><S><F><L><S><E><R><K><T><I><S><L><S><G><C><A><V><Q><M><F><L><S><L><A><M... | Odorant receptor.<BOP> | Q8NGS8 |
Q13115 | DUS4_HUMAN | Mitogen-activated protein kinase phosphatase 2 | Homo | <M><V><T><M><E><E><L><R><E><M><D><C><S><V><L><K><R><L><M><N><R><D><E><N><G><G><G><A><G><G><S><G><S><H><G><T><L><G><L><P><S><G><G><K><C><L><L><L><D><C><R><P><F><L><A><H><S><A><G><Y><I><L><G><S><V><N><V><R><C><N><T><I><V><R><R><R><A><K><G><S><V><S><L><E><Q><I><L><P><A><E><E><E><V><R><A><R><L><R><S><G><L><Y><S><A><V><I><V... | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.<BOP> | Q13115 |
P10747 | CD28_HUMAN | TP44 | Homo | <M><L><R><L><L><L><A><L><N><L><F><P><S><I><Q><V><T><G><N><K><I><L><V><K><Q><S><P><M><L><V><A><Y><D><N><A><V><N><L><S><C><K><Y><S><Y><N><L><F><S><R><E><F><R><A><S><L><H><K><G><L><D><S><A><V><E><V><C><V><V><Y><G><N><Y><S><Q><Q><L><Q><V><Y><S><K><T><G><F><N><C><D><G><K><L><G><N><E><S><V><T><F><Y><L><Q><N><L><Y><V><N><Q><T... | Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation . Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and ... | P10747 |
Q9H2X8 | I27L2_HUMAN | pIFI27-like protein | Homo | <M><M><K><R><A><A><A><A><A><V><G><G><A><L><A><V><G><A><V><P><V><V><L><S><A><M><G><F><T><G><A><G><I><A><A><S><S><I><A><A><K><M><M><S><A><A><A><I><A><N><G><G><G><V><S><A><G><S><L><V><A><T><L><Q><S><V><G><A><A><G><L><S><T><S><S><N><I><L><L><A><S><V><G><S><V><L><G><A><C><L><G><N><S><P><S><S><S><L><P><A><E><P><E><A><K><E><D... | Plays a role in the apoptotic process and has a pro-apoptotic activity.<BOP> | Q9H2X8 |
Q02086 | SP2_HUMAN | Transcription factor Sp2 | Homo | <M><S><D><P><Q><T><S><M><A><A><T><A><A><V><S><P><S><D><Y><L><Q><P><A><A><S><T><T><Q><D><S><Q><P><S><P><L><A><L><L><A><A><T><C><S><K><I><G><P><P><A><V><E><A><A><V><T><P><P><A><P><P><Q><P><T><P><R><K><L><V><P><I><K><P><A><P><L><P><L><S><P><G><K><N><S><F><G><I><L><S><S><K><G><N><I><L><Q><I><Q><G><S><Q><L><S><A><S><Y><P><G... | Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.<BOP> | Q02086 |
A6NHA9 | O4C46_HUMAN | Olfactory receptor 4C46 | Homo | <M><E><N><R><N><N><M><T><E><F><V><L><L><G><L><T><E><N><P><K><M><Q><K><I><I><F><V><V><F><F><V><I><Y><I><I><T><V><V><G><Y><V><L><I><V><V><T><I><T><A><S><P><S><L><G><S><P><M><Y><L><S><L><A><Y><L><S><F><I><D><A><C><Y><S><S><V><N><T><P><N><L><I><T><H><S><L><Y><G><K><K><A><I><L><F><N><G><C><M><T><Q><V><F><G><E><H><F><F><G><G... | Odorant receptor.<BOP> | A6NHA9 |
P17481 | HXB8_HUMAN | Homeobox protein Hox-2D | Homo | <M><S><S><Y><F><V><N><S><L><F><S><K><Y><K><T><G><E><S><L><R><P><N><Y><Y><D><C><G><F><A><Q><D><L><G><G><R><P><T><V><V><Y><G><P><S><S><G><G><S><F><Q><H><P><S><Q><I><Q><E><F><Y><H><G><P><S><S><L><S><T><A><P><Y><Q><Q><N><P><C><A><V><A><C><H><G><D><P><G><N><F><Y><G><Y><D><P><L><Q><R><Q><S><L><F><G><A><Q><D><P><D><L><V><Q><Y... | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP> | P17481 |
Q86VN1 | VPS36_HUMAN | ESCRT-II complex subunit VPS36 | Homo | <M><D><R><F><V><W><T><S><G><L><L><E><I><N><E><T><L><V><I><Q><Q><R><G><V><R><I><Y><D><G><E><E><K><I><K><F><D><A><G><T><L><L><L><S><T><H><R><L><I><W><R><D><Q><K><N><H><E><C><C><M><A><I><L><L><S><Q><I><V><F><I><E><E><Q><A><A><G><I><G><K><S><A><K><I><V><V><H><L><H><P><A><P><P><N><K><E><P><G><P><F><Q><S><S><K><N><S><Y><I><K... | Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II c... | Q86VN1 |
Q5T4B2 | GT253_HUMAN | Cerebral endothelial cell adhesion molecule | Homo | <M><R><A><A><R><A><A><P><L><L><Q><L><L><L><L><L><G><P><W><L><E><A><A><G><V><A><E><S><P><L><P><A><V><V><L><A><I><L><A><R><N><A><E><H><S><L><P><H><Y><L><G><A><L><E><R><L><D><Y><P><R><A><R><M><A><L><W><C><A><T><D><H><N><V><D><N><T><T><E><M><L><Q><E><W><L><A><A><V><G><D><D><Y><A><A><V><V><W><R><P><E><G><E><P><R><F><Y><P><D... | Probable cell adhesion protein involved in leukocyte transmigration across the blood-brain barrier. Does not express any beta-galactosyltransferase activity in vitro.<BOP> | Q5T4B2 |
Q8N1S5 | S39AB_HUMAN | Zrt- and Irt-like protein 11 | Homo | <M><L><Q><G><H><S><S><V><F><Q><A><L><L><G><T><F><F><T><W><G><M><T><A><A><G><A><A><L><V><F><V><F><S><S><G><Q><R><R><I><L><D><G><S><L><G><F><A><A><G><V><M><L><A><A><S><Y><W><S><L><L><A><P><A><V><E><M><A><T><S><S><G><G><F><G><A><F><A><F><F><P><V><A><V><G><F><T><L><G><A><A><F><V><Y><L><A><D><L><L><M><P><H><L><G><A><A><E><D... | Functions as a cellular zinc transporter.<BOP> | Q8N1S5 |
Q15612 | OR1Q1_HUMAN | Olfactory receptor TPCR106 | Homo | <M><D><N><S><N><W><T><S><V><S><H><F><V><L><L><G><I><S><T><H><P><E><E><Q><I><P><L><F><L><V><F><S><L><M><Y><A><I><N><I><S><G><N><L><A><I><I><T><L><I><L><S><A><P><R><L><H><I><P><M><Y><I><F><L><S><N><L><A><L><T><D><I><C><F><T><S><T><T><V><P><K><M><L><Q><I><I><F><S><P><T><K><V><I><S><Y><T><G><C><L><A><Q><T><Y><F><F><I><C><F... | Odorant receptor.<BOP> | Q15612 |
Q68D85 | NR3L1_HUMAN | B7 homolog 6 | Homo | <M><T><W><R><A><A><A><S><T><C><A><A><L><L><I><L><L><W><A><L><T><T><E><G><D><L><K><V><E><M><M><A><G><G><T><Q><I><T><P><L><N><D><N><V><T><I><F><C><N><I><F><Y><S><Q><P><L><N><I><T><S><M><G><I><T><W><F><W><K><S><L><T><F><D><K><E><V><K><V><F><E><F><F><G><D><H><Q><E><A><F><R><P><G><A><I><V><S><P><W><R><L><K><S><G><D><A><S><L... | Triggers NCR3-dependent natural killer cell activation.<BOP> | Q68D85 |
Q96LC9 | BMF_HUMAN | Bcl-2-modifying factor | Homo | <M><E><P><S><Q><C><V><E><E><L><E><D><D><V><F><Q><P><E><D><G><E><P><V><T><Q><P><G><S><L><L><S><A><D><L><F><A><Q><S><L><L><D><C><P><L><S><R><L><Q><L><F><P><L><T><H><C><C><G><P><G><L><R><P><T><S><Q><E><D><K><A><T><Q><T><L><S><P><A><S><P><S><Q><G><V><M><L><P><C><G><V><T><E><E><P><Q><R><L><F><Y><G><N><A><G><Y><R><L><P><L><P... | May play a role in apoptosis. Isoform 1 seems to be the main initiator.<BOP> | Q96LC9 |
Q08AI6 | S38AB_HUMAN | Solute carrier family 38 member 11 | Homo | <M><K><Q><A><G><F><P><L><G><I><L><L><L><F><W><V><S><Y><V><T><D><F><S><L><V><L><L><I><K><G><G><A><L><S><G><T><D><T><Y><Q><S><L><V><N><K><T><F><G><F><P><G><Y><L><L><L><S><V><L><Q><F><L><Y><P><F><I><A><M><I><S><Y><N><I><I><A><G><D><T><L><S><K><V><F><Q><R><I><P><G><V><D><P><E><N><V><F><I><G><R><H><F><I><I><G><L><S><T><V><T... | Putative sodium-dependent amino acid/proton antiporter.<BOP> | Q08AI6 |
O75629 | CREG1_HUMAN | Cellular repressor of E1A-stimulated genes 1 | Homo | <M><A><G><L><S><R><G><S><A><R><A><L><L><A><A><L><L><A><S><T><L><L><A><L><L><V><S><P><A><R><G><R><G><G><R><D><H><G><D><W><D><E><A><S><R><L><P><P><L><P><P><R><E><D><A><A><R><V><A><R><F><V><T><H><V><S><D><W><G><A><L><A><T><I><S><T><L><E><A><V><R><G><R><P><F><A><D><V><L><S><L><S><D><G><P><P><G><A><G><S><G><V><P><Y><F><Y><L... | May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.<BOP> | O75629 |
O75381 | PEX14_HUMAN | Peroxisomal membrane anchor protein PEX14 | Homo | <M><A><S><S><E><Q><A><E><Q><P><S><Q><P><S><S><T><P><G><S><E><N><V><L><P><R><E><P><L><I><A><T><A><V><K><F><L><Q><N><S><R><V><R><Q><S><P><L><A><T><R><R><A><F><L><K><K><K><G><L><T><D><E><E><I><D><M><A><F><Q><Q><S><G><T><A><A><D><E><P><S><S><L><G><P><A><T><Q><V><V><P><V><Q><P><P><H><L><I><S><Q><P><Y><S><P><A><G><S><R><W><R... | Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.<BOP> | O75381 |
P07438 | MT1B_HUMAN | Metallothionein-IB | Homo | <M><D><P><N><C><S><C><T><T><G><G><S><C><A><C><A><G><S><C><K><C><K><E><C><K><C><T><S><C><K><K><C><C><C><S><C><C><P><V><G><C><A><K><C><A><Q><G><C><V><C><K><G><S><S><E><K><C><R><C><C><A> | Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.<BOP> | P07438 |
O15321 | TM9S1_HUMAN | MP70 protein family member | Homo | <M><T><V><V><G><N><P><R><S><W><S><C><Q><W><L><P><I><L><I><L><L><L><G><T><G><H><G><P><G><V><E><G><V><T><H><Y><K><A><G><D><P><V><I><L><Y><V><N><K><V><G><P><Y><H><N><P><Q><E><T><Y><H><Y><Y><Q><L><P><V><C><C><P><E><K><I><R><H><K><S><L><S><L><G><E><V><L><D><G><D><R><M><A><E><S><L><Y><E><I><R><F><R><E><N><V><E><K><R><I><L><C... | Plays an essential role in autophagy.<BOP> | O15321 |
Q9H9S5 | FKRP_HUMAN | Ribitol-5-phosphate transferase | Homo | <M><R><L><T><R><C><Q><A><A><L><A><A><A><I><T><L><N><L><L><V><L><F><Y><V><S><W><L><Q><H><Q><P><R><N><S><R><A><R><G><P><R><R><A><S><A><A><G><P><R><V><T><V><L><V><R><E><F><E><A><F><D><N><A><V><P><E><L><V><D><S><F><L><Q><Q><D><P><A><Q><P><V><V><V><A><A><D><T><L><P><Y><P><P><L><A><L><P><R><I><P><N><V><R><L><A><L><L><Q><P><A... | Catalyzes the transfer of a ribitol 5-phosphate from CDP-L-ribitol to the ribitol 5-phosphate previously attached by FKTN/fukutin to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) ... | Q9H9S5 |
Q6PIZ9 | TRAT1_HUMAN | pp29/30 | Homo | <M><S><G><I><S><G><C><P><F><F><L><W><G><L><L><A><L><L><G><L><A><L><V><I><S><L><I><F><N><I><S><H><Y><V><E><K><Q><R><Q><D><K><M><Y><S><Y><S><S><D><H><T><R><V><D><E><Y><Y><I><E><D><T><P><I><Y><G><N><L><D><D><M><I><S><E><P><M><D><E><N><C><Y><E><Q><M><K><A><R><P><E><K><S><V><N><K><M><Q><E><A><T><P><S><A><Q><A><T><N><E><T><Q... | Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.<BOP> | Q6PIZ9 |
Q8NGP2 | OR8J1_HUMAN | Olfactory receptor OR11-183 | Homo | <M><A><P><E><N><F><T><R><V><T><E><F><I><L><T><G><V><S><S><C><P><E><L><Q><I><P><L><F><L><V><F><L><V><L><Y><G><L><T><M><A><G><N><L><G><I><I><T><L><T><S><V><D><S><R><L><Q><T><P><M><Y><F><F><L><Q><H><L><A><L><I><N><L><G><N><S><T><V><I><A><P><K><M><L><I><N><F><L><V><K><K><K><T><T><S><F><Y><E><C><A><T><Q><L><G><G><F><L><F><F... | Odorant receptor.<BOP> | Q8NGP2 |
Q96JW4 | S41A2_HUMAN | Solute carrier family 41 member 2 | Homo | <M><T><N><S><K><G><R><S><I><T><D><K><T><S><G><G><P><S><S><G><G><G><F><V><D><W><T><L><R><L><N><T><I><Q><S><D><K><F><L><N><L><L><L><S><M><V><P><V><I><Y><Q><K><N><Q><E><D><R><H><K><K><A><N><G><I><W><Q><D><G><L><S><T><A><V><Q><T><F><S><N><R><S><E><Q><H><M><E><Y><H><S><F><S><E><Q><S><F><H><A><N><N><G><H><A><S><S><S><C><S><Q... | Acts as a plasma-membrane magnesium transporter.<BOP> | Q96JW4 |
Q96BT7 | ALKB8_HUMAN | tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 | Homo | <M><D><S><N><H><Q><S><N><Y><K><L><S><K><T><E><K><K><F><L><R><K><Q><I><K><A><K><H><T><L><L><R><H><E><G><I><E><T><V><S><Y><A><T><Q><S><L><V><V><A><N><G><G><L><G><N><G><V><S><R><N><Q><L><L><P><V><L><E><K><C><G><L><V><D><A><L><L><M><P><P><N><K><P><Y><S><F><A><R><Y><R><T><T><E><E><S><K><R><A><Y><V><T><L><N><G><K><E><V><V><D... | Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain . Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA . Has a pref... | Q96BT7 |
P28347 | TEAD1_HUMAN | Transcription factor 13 | Homo | <M><E><P><S><S><W><S><G><S><E><S><P><A><E><N><M><E><R><M><S><D><S><A><D><K><P><I><D><N><D><A><E><G><V><W><S><P><D><I><E><Q><S><F><Q><E><A><L><A><I><Y><P><P><C><G><R><R><K><I><I><L><S><D><E><G><K><M><Y><G><R><N><E><L><I><A><R><Y><I><K><L><R><T><G><K><T><R><T><R><K><Q><V><S><S><H><I><Q><V><L><A><R><R><K><S><R><D><F><H><S... | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosph... | P28347 |
Q14512 | FGFP1_HUMAN | 17 kDa heparin-binding growth factor-binding protein | Homo | <M><K><I><C><S><L><T><L><L><S><F><L><L><L><A><A><Q><V><L><L><V><E><G><K><K><K><V><K><N><G><L><H><S><K><V><V><S><E><Q><K><D><T><L><G><N><T><Q><I><K><Q><K><S><R><P><G><N><K><G><K><F><V><T><K><D><Q><A><N><C><R><W><A><A><T><E><Q><E><E><G><I><S><L><K><V><E><C><T><Q><L><D><H><E><F><S><C><V><F><A><G><N><P><T><S><C><L><K><L><K... | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.<BOP> | Q14512 |
P31785 | IL2RG_HUMAN | p64 | Homo | <M><L><K><P><S><L><P><F><T><S><L><L><F><L><Q><L><P><L><L><G><V><G><L><N><T><T><I><L><T><P><N><G><N><E><D><T><T><A><D><F><F><L><T><T><M><P><T><D><S><L><S><V><S><T><L><P><L><P><E><V><Q><C><F><V><F><N><V><E><Y><M><N><C><T><W><N><S><S><S><E><P><Q><P><T><N><L><T><L><H><Y><W><Y><K><N><S><D><N><D><K><V><Q><K><C><S><H><Y><L><F... | Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 .<BOP> | P31785 |
Q86T90 | K1328_HUMAN | Protein hinderin | Homo | <M><A><D><V><A><G><P><S><R><P><S><A><A><A><F><W><S><R><D><F><S><D><E><E><Q><S><V><V><Y><V><P><G><I><S><A><E><G><N><V><R><S><R><H><K><L><M><S><P><K><A><D><V><K><L><K><T><S><R><V><T><D><A><S><I><S><M><E><S><L><K><G><T><G><D><S><V><D><E><Q><N><S><C><R><G><E><I><K><S><A><S><L><K><D><L><C><L><E><D><K><R><R><I><A><N><L><I><K... | Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes.<BOP> | Q86T90 |
Q99518 | FMO2_HUMAN | Pulmonary flavin-containing monooxygenase 2 | Homo | <M><A><K><K><V><A><V><I><G><A><G><V><S><G><L><I><S><L><K><C><C><V><D><E><G><L><E><P><T><C><F><E><R><T><E><D><I><G><G><V><W><R><F><K><E><N><V><E><D><G><R><A><S><I><Y><Q><S><V><V><T><N><T><S><K><E><M><S><C><F><S><D><F><P><M><P><E><D><F><P><N><F><L><H><N><S><K><L><L><E><Y><F><R><I><F><A><K><K><F><D><L><L><K><Y><I><Q><F><Q... | Catalyzes the oxidative metabolism of numerous xenobiotics, including mainly therapeutic drugs and insecticides that contain a soft nucleophile, most commonly nitrogen and sulfur and participates to their bioactivation . Specifically catalyzes S-oxygenation of sulfur derived compounds such as thioureas-derived compound... | Q99518 |
O95571 | ETHE1_HUMAN | Sulfur dioxygenase ETHE1 | Homo | <M><A><E><A><V><L><R><V><A><R><R><Q><L><S><Q><R><G><G><S><G><A><P><I><L><L><R><Q><M><F><E><P><V><S><C><T><F><T><Y><L><L><G><D><R><E><S><R><E><A><V><L><I><D><P><V><L><E><T><A><P><R><D><A><Q><L><I><K><E><L><G><L><R><L><L><Y><A><V><N><T><H><C><H><A><D><H><I><T><G><S><G><L><L><R><S><L><L><P><G><C><Q><S><V><I><S><R><L><S><G... | Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thi... | O95571 |
Q9Y6M0 | TEST_HUMAN | Serine protease 21 | Homo | <M><G><A><R><G><A><L><L><L><A><L><L><L><A><R><A><G><L><R><K><P><E><S><Q><E><A><A><P><L><S><G><P><C><G><R><R><V><I><T><S><R><I><V><G><G><E><D><A><E><L><G><R><W><P><W><Q><G><S><L><R><L><W><D><S><H><V><C><G><V><S><L><L><S><H><R><W><A><L><T><A><A><H><C><F><E><T><Y><S><D><L><S><D><P><S><G><W><M><V><Q><F><G><Q><L><T><S><M><P... | Could regulate proteolytic events associated with testicular germ cell maturation.<BOP> | Q9Y6M0 |
Q9H081 | MIS12_HUMAN | Protein MIS12 homolog | Homo | <M><S><V><D><P><M><T><Y><E><A><Q><F><F><G><F><T><P><Q><T><C><M><L><R><I><Y><I><A><F><Q><D><Y><L><F><E><V><M><Q><A><V><E><Q><V><I><L><K><K><L><D><G><I><P><D><C><D><I><S><P><V><Q><I><R><K><C><T><E><K><F><L><C><F><M><K><G><H><F><D><N><L><F><S><K><M><E><Q><L><F><L><Q><L><I><L><R><I><P><S><N><I><L><L><P><E><D><K><C><K><E><T... | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis . Essential for proper kinetochore microtubule attachments .<BOP> | Q9H081 |
Q8N8Q8 | COX18_HUMAN | Cytochrome c oxidase assembly protein 18 | Homo | <M><L><C><R><L><G><G><R><W><L><R><P><L><P><A><L><Q><L><W><A><R><D><L><P><L><A><P><V><P><T><S><G><A><K><R><P><T><L><P><V><W><A><V><A><P><V><S><A><V><H><A><N><G><W><Y><E><A><L><A><A><S><S><P><V><R><V><A><E><E><V><L><L><G><V><H><A><A><T><G><L><P><W><W><G><S><I><L><L><S><T><V><A><L><R><G><A><V><T><L><P><L><A><A><Y><Q><H><Y... | Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of ... | Q8N8Q8 |
O14763 | TR10B_HUMAN | TNF-related apoptosis-inducing ligand receptor 2 | Homo | <M><E><Q><R><G><Q><N><A><P><A><A><S><G><A><R><K><R><H><G><P><G><P><R><E><A><R><G><A><R><P><G><P><R><V><P><K><T><L><V><L><V><V><A><A><V><L><L><L><V><S><A><E><S><A><L><I><T><Q><Q><D><L><A><P><Q><Q><R><A><A><P><Q><Q><K><R><S><S><P><S><E><G><L><C><P><P><G><H><H><I><S><E><D><G><R><D><C><I><S><C><K><Y><G><Q><D><Y><S><T><H><W... | Receptor for the cytotoxic ligand TNFSF10/TRAIL . The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating a... | O14763 |
O00501 | CLD5_HUMAN | Transmembrane protein deleted in VCFS | Homo | <M><G><S><A><A><L><E><I><L><G><L><V><L><C><L><V><G><W><G><G><L><I><L><A><C><G><L><P><M><W><Q><V><T><A><F><L><D><H><N><I><V><T><A><Q><T><T><W><K><G><L><W><M><S><C><V><V><Q><S><T><G><H><M><Q><C><K><V><Y><D><S><V><L><A><L><S><T><E><V><Q><A><A><R><A><L><T><V><S><A><V><L><L><A><F><V><A><L><F><V><T><L><A><G><A><Q><C><T><T><C... | Plays a major role in tight junction-specific obliteration of the intercellular space.<BOP> | O00501 |
Q96EF6 | FBX17_HUMAN | F-box only protein 26 | Homo | <M><G><A><R><L><S><R><R><R><L><P><A><D><P><S><L><A><L><D><A><L><P><P><E><L><L><V><Q><V><L><S><H><V><P><P><R><S><L><V><T><R><C><R><P><V><C><R><A><W><R><D><I><V><D><G><P><T><V><W><L><L><Q><L><A><R><D><R><S><A><E><G><R><A><L><Y><A><V><A><Q><R><C><L><P><S><N><E><D><K><E><E><F><P><L><C><A><L><A><R><Y><C><L><R><A><P><F><G><R... | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins.<BOP> | Q96EF6 |
Q9H1K6 | TLRN1_HUMAN | Mesoderm development candidate 1 | Homo | <M><A><S><G><S><A><G><K><P><T><G><E><A><A><S><P><A><P><A><S><A><I><G><G><A><S><S><Q><P><R><K><R><L><V><S><V><C><D><H><C><K><G><K><M><Q><L><V><A><D><L><L><L><L><S><S><E><A><R><P><V><L><F><E><G><P><A><S><S><G><A><G><A><E><S><F><E><Q><C><R><D><T><I><I><A><R><T><K><G><L><S><I><L><T><H><D><V><Q><S><Q><L><N><M><G><R><F><G><E... | Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells.<BOP> | Q9H1K6 |
Q9Y585 | OR1A2_HUMAN | Olfactory receptor OR17-10 | Homo | <M><K><K><E><N><Q><S><F><N><L><D><F><I><L><L><G><V><T><S><Q><Q><E><Q><N><N><V><F><F><V><I><F><L><C><I><Y><P><I><T><L><T><G><N><L><L><I><I><L><A><I><C><A><D><I><R><L><H><N><P><M><Y><F><L><L><A><N><L><S><L><V><D><I><I><F><S><S><V><T><I><P><K><V><L><A><N><H><L><L><G><S><K><F><I><S><F><G><G><C><L><M><Q><M><Y><F><M><I><A><L... | Odorant receptor.<BOP> | Q9Y585 |
Q14CN4 | K2C72_HUMAN | Type-II keratin Kb35 | Homo | <M><S><R><Q><L><T><H><F><P><R><G><E><R><L><G><F><S><G><C><S><A><V><L><S><G><G><I><G><S><S><S><A><S><F><R><A><R><V><K><G><S><A><S><F><G><S><K><S><L><S><C><L><G><G><S><R><S><L><A><L><S><A><A><A><R><R><G><G><G><R><L><G><G><F><V><G><T><A><F><G><S><A><G><L><G><P><K><C><P><S><V><C><P><P><G><G><I><P><Q><V><T><V><N><K><S><L><L... | Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).<BOP> | Q14CN4 |
O76061 | STC2_HUMAN | Stanniocalcin-related protein | Homo | <M><C><A><E><R><L><G><Q><F><M><T><L><A><L><V><L><A><T><F><D><P><A><R><G><T><D><A><T><N><P><P><E><G><P><Q><D><R><S><S><Q><Q><K><G><R><L><S><L><Q><N><T><A><E><I><Q><H><C><L><V><N><A><G><D><V><G><C><G><V><F><E><C><F><E><N><N><S><C><E><I><R><G><L><H><G><I><C><M><T><F><L><H><N><A><G><K><F><D><A><Q><G><K><S><F><I><K><D><A><L... | Has an anti-hypocalcemic action on calcium and phosphate homeostasis.<BOP> | O76061 |
Q96DN0 | ERP27_HUMAN | Inactive protein disulfide-isomerase 27 | Homo | <M><E><A><A><P><S><R><F><M><F><L><L><F><L><L><T><C><E><L><A><A><E><V><A><A><E><V><E><K><S><S><D><G><P><G><A><A><Q><E><P><T><W><L><T><D><V><P><A><A><M><E><F><I><A><A><T><E><V><A><V><I><G><F><F><Q><D><L><E><I><P><A><V><P><I><L><H><S><M><V><Q><K><F><P><G><V><S><F><G><I><S><T><D><S><E><V><L><T><H><Y><N><I><T><G><N><T><I><C... | Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates . Binds protein substrates via a hydrophobic pocket in the C-terminal domain . May play a role in the unfolded stress response .<BOP> | Q96DN0 |
Q99677 | LPAR4_HUMAN | Purinergic receptor 9 | Homo | <M><G><D><R><R><F><I><D><F><Q><F><Q><D><S><N><S><S><L><R><P><R><L><G><N><A><T><A><N><N><T><C><I><V><D><D><S><F><K><Y><N><L><N><G><A><V><Y><S><V><V><F><I><L><G><L><I><T><N><S><V><S><L><F><V><F><C><F><R><M><K><M><R><S><E><T><A><I><F><I><T><N><L><A><V><S><D><L><L><F><V><C><T><L><P><F><K><I><F><Y><N><F><N><R><H><W><P><F><G... | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- ... | Q99677 |
Q96F85 | CNRP1_HUMAN | CB1 cannabinoid receptor-interacting protein 1 | Homo | <M><G><D><L><P><G><L><V><R><L><S><I><A><L><R><I><Q><P><N><D><G><P><V><F><Y><K><V><D><G><Q><R><F><G><Q><N><R><T><I><K><L><L><T><G><S><S><Y><K><V><E><V><K><I><K><P><S><T><L><Q><V><E><N><I><S><I><G><G><V><L><V><P><L><E><L><K><S><K><E><P><D><G><D><R><V><V><Y><T><G><T><Y><D><T><E><G><V><T><P><T><K><S><G><E><R><Q><P><I><Q><I... | Does not suppress cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.<BOP> | Q96F85 |
O60739 | EIF1B_HUMAN | Protein translation factor SUI1 homolog GC20 | Homo | <M><S><T><I><Q><N><L><Q><S><F><D><P><F><A><D><A><T><K><G><D><D><L><L><P><A><G><T><E><D><Y><I><H><I><R><I><Q><Q><R><N><G><R><K><T><L><T><T><V><Q><G><I><A><D><D><Y><D><K><K><K><L><V><K><A><F><K><K><K><F><A><C><N><G><T><V><I><E><H><P><E><Y><G><E><V><I><Q><L><Q><G><D><Q><R><K><N><I><C><Q><F><L><L><E><V><G><I><V><K><E><E><Q... | Probably involved in translation.<BOP> | O60739 |
Q15124 | PGM5_HUMAN | Phosphoglucomutase-related protein | Homo | <M><E><G><S><P><I><P><V><L><T><V><P><T><A><P><Y><E><D><Q><R><P><A><G><G><G><G><L><R><R><P><T><G><L><F><E><G><Q><R><N><Y><L><P><N><F><I><Q><S><V><L><S><S><I><D><L><R><D><R><Q><G><C><T><M><V><V><G><S><D><G><R><Y><F><S><R><T><A><I><E><I><V><V><Q><M><A><A><A><N><G><I><G><R><L><I><I><G><Q><N><G><I><L><S><T><P><A><V><S><C><I... | Component of adherens-type cell-cell and cell-matrix junctions . Has no phosphoglucomutase activity in vitro .<BOP> | Q15124 |
Q9BTV7 | CABL2_HUMAN | Interactor with CDK3 2 | Homo | <M><A><A><A><A><A><G><G><A><P><G><P><A><P><G><P><A><G><P><P><P><P><A><A><P><T><S><A><A><R><A><P><P><Q><A><L><R><R><R><G><D><S><R><R><R><Q><A><A><L><F><F><L><N><N><I><S><L><D><G><R><P><P><S><L><G><P><G><G><E><K><P><P><P><P><P><A><E><A><R><E><P><P><A><P><P><P><P><E><P><P><T><G><L><P><A><R><T><P><A><P><Q><G><L><L><S><P><T... | Unknown. Probably involved in G1-S cell cycle transition.<BOP> | Q9BTV7 |
Q9Y5Y0 | FLVC1_HUMAN | Feline leukemia virus subgroup C receptor-related protein 1 | Homo | <M><A><R><P><D><D><E><E><G><A><A><V><A><P><G><H><P><L><A><K><G><Y><L><P><L><P><R><G><A><P><V><G><K><E><S><V><E><L><Q><N><G><P><K><A><G><T><F><P><V><N><G><A><P><R><D><S><L><A><A><A><S><G><V><L><G><G><P><Q><T><P><L><A><P><E><E><E><T><Q><A><R><L><L><P><A><G><A><G><A><E><T><P><G><A><E><S><S><P><L><P><L><T><A><L><S><P><R><R... | Heme transporter that promotes heme efflux from the mitochondrion to the cytoplasm. Essential for erythroid differentiation.<BOP> | Q9Y5Y0 |
O15228 | GNPAT_HUMAN | Glycerone-phosphate O-acyltransferase | Homo | <M><E><S><S><S><S><S><N><S><Y><F><S><V><G><P><T><S><P><S><A><V><V><L><L><Y><S><K><E><L><K><K><W><D><E><F><E><D><I><L><E><E><R><R><H><V><S><D><L><K><F><A><M><K><C><Y><T><P><L><V><Y><K><G><I><T><P><C><K><P><I><D><I><K><C><S><V><L><N><S><E><E><I><H><Y><V><I><K><Q><L><S><K><E><S><L><Q><S><V><D><V><L><R><E><E><V><S><E><I><L... | Dihydroxyacetonephosphate acyltransferase involved in plasmalogen biosynthesis.<BOP> | O15228 |
Q8WXG1 | RSAD2_HUMAN | Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible | Homo | <M><W><V><L><T><P><A><A><F><A><G><K><L><L><S><V><F><R><Q><P><L><S><S><L><W><R><S><L><V><P><L><F><C><W><L><R><A><T><F><W><L><L><A><T><K><R><R><K><Q><Q><L><V><L><R><G><P><D><E><T><K><E><E><E><E><D><P><P><L><P><T><T><P><T><S><V><N><Y><H><F><T><R><Q><C><N><Y><K><C><G><F><C><F><H><T><A><K><T><S><F><V><L><P><L><E><E><A><K><R... | Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon . Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) via a SAM-dependent radical mechanism . In turn, ddhCTP acts as a chain terminator for t... | Q8WXG1 |
Q9NUV7 | SPTC3_HUMAN | Serine-palmitoyl-CoA transferase 3 | Homo | <M><A><N><P><G><G><G><A><V><C><N><G><K><L><H><N><H><K><K><Q><S><N><G><S><Q><S><R><N><C><T><K><N><G><I><V><K><E><A><Q><Q><N><G><K><P><H><F><Y><D><K><L><I><V><E><S><F><E><E><A><P><L><H><V><M><V><F><T><Y><M><G><Y><G><I><G><T><L><F><G><Y><L><R><D><F><L><R><N><W><G><I><E><K><C><N><A><A><V><E><R><K><E><Q><K><D><F><V><P><L><Y... | Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. SPT complexes containing SPTLC3 generate shorter chain sphingoid bases compared to complexes containing SPTLC2.... | Q9NUV7 |
Q155Q3 | DIXC1_HUMAN | DIX domain-containing protein 1 | Homo | <M><L><A><C><L><T><R><G><N><L><L><D><V><L><Q><E><G><F><N><E><Q><Q><L><Q><A><Y><V><A><W><V><N><A><Q><L><K><K><R><P><A><V><K><P><V><Q><D><L><R><Q><D><L><R><D><G><V><I><L><A><Y><L><I><E><I><V><A><G><E><K><L><S><G><V><Q><L><S><P><G><N><Q><Q><E><M><K><N><N><V><E><K><V><L><Q><F><V><A><S><K><K><I><R><M><H><Q><T><S><A><K><D><I... | Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.<BOP> | Q155Q3 |
Q86YD1 | PTOV1_HUMAN | Activator interaction domain-containing protein 2 | Homo | <M><V><R><P><R><R><A><P><Y><R><S><G><A><G><G><P><L><G><G><R><G><R><P><P><R><P><L><V><V><R><A><V><R><S><R><S><W><P><A><S><P><R><G><P><Q><P><P><R><I><R><A><R><S><A><P><P><M><E><G><A><R><V><F><G><A><L><G><P><I><G><P><S><S><P><G><L><T><L><G><G><L><A><V><S><E><H><R><L><S><N><K><L><L><A><W><S><G><V><L><E><W><Q><E><K><R><R><P... | May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.<BOP> | Q86YD1 |
O43614 | OX2R_HUMAN | Hypocretin receptor type 2 | Homo | <M><S><G><T><K><L><E><D><S><P><P><C><R><N><W><S><S><A><S><E><L><N><E><T><Q><E><P><F><L><N><P><T><D><Y><D><D><E><E><F><L><R><Y><L><W><R><E><Y><L><H><P><K><E><Y><E><W><V><L><I><A><G><Y><I><I><V><F><V><V><A><L><I><G><N><V><L><V><C><V><A><V><W><K><N><H><H><M><R><T><V><T><N><Y><F><I><V><N><L><S><L><A><D><V><L><V><T><I><T><C... | Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides . Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding .<BOP> | O43614 |
P23219 | PGH1_HUMAN | Prostaglandin-endoperoxide synthase 1 | Homo | <M><S><R><S><L><L><L><W><F><L><L><F><L><L><L><L><P><P><L><P><V><L><L><A><D><P><G><A><P><T><P><V><N><P><C><C><Y><Y><P><C><Q><H><Q><G><I><C><V><R><F><G><L><D><R><Y><Q><C><D><C><T><R><T><G><Y><S><G><P><N><C><T><I><P><G><L><W><T><W><L><R><N><S><L><R><P><S><P><S><F><T><H><F><L><L><T><H><G><R><W><F><W><E><F><V><N><A><T><F><I... | Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate, with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates arachidonate (AA, C20:4(n-6)) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and... | P23219 |
O75112 | LDB3_HUMAN | Z-band alternatively spliced PDZ-motif protein | Homo | <M><S><Y><S><V><T><L><T><G><P><G><P><W><G><F><R><L><Q><G><G><K><D><F><N><M><P><L><T><I><S><R><I><T><P><G><S><K><A><A><Q><S><Q><L><S><Q><G><D><L><V><V><A><I><D><G><V><N><T><D><T><M><T><H><L><E><A><Q><N><K><I><K><S><A><S><Y><N><L><S><L><T><L><Q><K><S><K><R><P><I><P><I><S><T><T><A><P><P><V><Q><T><P><L><P><V><I><P><H><Q><K... | May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.<BOP> | O75112 |
Q6ZMD2 | SPNS3_HUMAN | Protein spinster homolog 3 | Homo | <M><A><G><G><M><S><A><E><C><P><E><P><G><P><G><G><L><Q><G><Q><S><P><G><P><G><R><Q><C><P><P><P><I><T><P><T><S><W><S><L><P><P><W><R><A><Y><V><A><A><A><V><L><C><Y><I><N><L><L><N><Y><M><N><W><F><I><I><A><G><V><L><L><D><I><Q><E><V><F><Q><I><S><D><N><H><A><G><L><L><Q><T><V><F><V><S><C><L><L><L><S><A><P><V><F><G><Y><L><G><D><R... | Sphingolipid transporter.<BOP> | Q6ZMD2 |
P41597 | CCR2_HUMAN | Monocyte chemoattractant protein 1 receptor | Homo | <M><L><S><T><S><R><S><R><F><I><R><N><T><N><E><S><G><E><E><V><T><T><F><F><D><Y><D><Y><G><A><P><C><H><K><F><D><V><K><Q><I><G><A><Q><L><L><P><P><L><Y><S><L><V><F><I><F><G><F><V><G><N><M><L><V><V><L><I><L><I><N><C><K><K><L><K><C><L><T><D><I><Y><L><L><N><L><A><I><S><D><L><L><F><L><I><T><L><P><L><W><A><H><S><A><A><N><E><W><V... | (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.<BOP> | P41597 |
O95059 | RPP14_HUMAN | Ribonuclease P protein subunit p14 | Homo | <M><P><A><P><A><A><T><Y><E><R><V><V><Y><K><N><P><S><E><Y><H><Y><M><K><V><C><L><E><F><Q><D><C><G><V><G><L><N><A><A><Q><F><K><Q><L><L><I><S><A><V><K><D><L><F><G><E><V><D><A><A><L><P><L><D><I><L><T><Y><E><E><K><T><L><S><A><I><L><R><I><C><S><S><G><L><V><K><L><W><S><S><L><T><L><L><G><S><Y><K><G><K><K><C><A><F><R><V><I><Q><V... | Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.<BOP> | O95059 |
Q15049 | MLC1_HUMAN | Membrane protein MLC1 | Homo | <M><T><Q><E><P><F><R><E><E><L><A><Y><D><R><M><P><T><L><E><R><G><R><Q><D><P><A><S><Y><A><P><D><A><K><P><S><D><L><Q><L><S><K><R><L><P><P><C><F><S><H><K><T><W><V><F><S><V><L><M><G><S><C><L><L><V><T><S><G><F><S><L><Y><L><G><N><V><F><P><A><E><M><D><Y><L><R><C><A><A><G><S><C><I><P><S><A><I><V><S><F><T><V><S><R><R><N><A><N><V... | Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.<BOP> | Q15049 |
Q6NVV9 | ADAM5_HUMAN | Putative transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II | Homo | <M><Q><T><S><I><L><I><K><S><S><C><R><P><Q><F><Q><R><R><F><H><H><R><M><Q><K><Q><I><Q><N><I><I><S><I><L><S><S><A><S><V><I><N><S><Y><D><E><N><D><I><R><H><S><K><P><L><L><V><Q><M><D><C><N><Y><N><G><Y><V><A><G><I><P><N><S><L><V><T><L><S><V><C><S><G><L><R><G><T><M><Q><L><K><N><I><S><Y><G><I><E><P><M><E><A><V><S><G><F><I><H><K... | This is a non catalytic metalloprotease-like protein.<BOP> | Q6NVV9 |
O00233 | PSMD9_HUMAN | 26S proteasome regulatory subunit p27 | Homo | <M><S><D><E><E><A><R><Q><S><G><G><S><S><Q><A><G><V><V><T><V><S><D><V><Q><E><L><M><R><R><K><E><E><I><E><A><Q><I><K><A><N><Y><D><V><L><E><S><Q><K><G><I><G><M><N><E><P><L><V><D><C><E><G><Y><P><R><S><D><V><D><L><Y><Q><V><R><T><A><R><H><N><I><I><C><L><Q><N><D><H><K><A><V><M><K><Q><V><E><E><A><L><H><Q><L><H><A><R><D><K><E><K... | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly... | O00233 |
P78562 | PHEX_HUMAN | X-linked hypophosphatemia protein | Homo | <M><E><A><E><T><G><S><S><V><E><T><G><K><K><A><N><R><G><T><R><I><A><L><V><V><F><V><G><G><T><L><V><L><G><T><I><L><F><L><V><S><Q><G><L><L><S><L><Q><A><K><Q><E><Y><C><L><K><P><E><C><I><E><A><A><A><A><I><L><S><K><V><N><L><S><V><D><P><C><D><N><F><F><R><F><A><C><D><G><W><I><S><N><N><P><I><P><E><D><M><P><S><Y><G><V><Y><P><W><L... | Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity . Cleaves ASARM peptides between Ser and Glu or Asp residues . Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derive... | P78562 |
Q96CS7 | PKHB2_HUMAN | Evectin-2 | Homo | <M><A><F><V><K><S><G><W><L><L><R><Q><S><T><I><L><K><R><W><K><K><N><W><F><D><L><W><S><D><G><H><L><I><Y><Y><D><D><Q><T><R><Q><N><I><E><D><K><V><H><M><P><M><D><C><I><N><I><R><T><G><Q><E><C><R><D><T><Q><P><P><D><G><K><S><K><D><C><M><L><Q><I><V><C><R><D><G><K><T><I><S><L><C><A><E><S><T><D><D><C><L><A><W><K><F><T><L><Q><D><S... | Involved in retrograde transport of recycling endosomes.<BOP> | Q96CS7 |
P48059 | LIMS1_HUMAN | Renal carcinoma antigen NY-REN-48 | Homo | <M><A><N><A><L><A><S><A><T><C><E><R><C><K><G><G><F><A><P><A><E><K><I><V><N><S><N><G><E><L><Y><H><E><Q><C><F><V><C><A><Q><C><F><Q><Q><F><P><E><G><L><F><Y><E><F><E><G><R><K><Y><C><E><H><D><F><Q><M><L><F><A><P><C><C><H><Q><C><G><E><F><I><I><G><R><V><I><K><A><M><N><N><S><W><H><P><E><C><F><R><C><D><L><C><Q><E><V><L><A><D><I... | Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.<BOP> | P48059 |
Q8N8G2 | VGLL2_HUMAN | Protein VITO1 | Homo | <M><S><C><L><D><V><M><Y><Q><V><Y><G><P><P><Q><P><Y><F><A><A><A><Y><T><P><Y><H><Q><K><L><A><Y><Y><S><K><M><Q><E><A><Q><E><C><N><A><S><P><S><S><S><G><S><G><S><S><S><F><S><S><Q><T><P><A><S><I><K><E><E><E><G><S><P><E><K><E><R><P><P><E><A><E><Y><I><N><S><R><C><V><L><F><T><Y><F><Q><G><D><I><S><S><V><V><D><E><H><F><S><R><A><L... | May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.<BOP> | Q8N8G2 |
Q86V88 | MGDP1_HUMAN | Magnesium-dependent phosphatase 1 | Homo | <M><A><R><L><P><K><L><A><V><F><D><L><D><Y><T><L><W><P><F><W><V><D><T><H><V><D><P><P><F><H><K><S><S><D><G><T><V><R><D><R><R><G><Q><D><V><R><L><Y><P><E><V><P><E><V><L><K><R><L><Q><S><L><G><V><P><G><A><A><A><S><R><T><S><E><I><E><G><A><N><Q><L><L><E><L><F><D><L><F><R><Y><F><V><H><R><E><I><Y><P><G><S><K><I><T><H><F><E><R><L... | Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.<BOP> | Q86V88 |
A0A0A0MRZ9 | LV552_HUMAN | Immunoglobulin lambda variable 5-52 | Homo | <M><A><W><T><L><L><L><L><V><L><L><S><H><C><T><G><S><L><S><Q><P><V><L><T><Q><P><S><S><H><S><A><S><S><G><A><S><V><R><L><T><C><M><L><S><S><G><F><S><V><G><D><F><W><I><R><W><Y><Q><Q><K><P><G><N><P><P><R><Y><L><L><Y><Y><H><S><D><S><N><K><G><Q><G><S><G><V><P><S><R><F><S><G><S><N><D><A><S><A><N><A><G><I><L><R><I><S><G><L><Q><P... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0A0MRZ9 |
O00764 | PDXK_HUMAN | Pyridoxine kinase | Homo | <M><E><E><E><C><R><V><L><S><I><Q><S><H><V><I><R><G><Y><V><G><N><R><A><A><T><F><P><L><Q><V><L><G><F><E><I><D><A><V><N><S><V><Q><F><S><N><H><T><G><Y><A><H><W><K><G><Q><V><L><N><S><D><E><L><Q><E><L><Y><E><G><L><R><L><N><N><M><N><K><Y><D><Y><V><L><T><G><Y><T><R><D><K><S><F><L><A><M><V><V><D><I><V><Q><E><L><K><Q><Q><N><P><R... | Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over ... | O00764 |
Q9ULW5 | RAB26_HUMAN | Ras-related protein Rab-26 | Homo | <M><S><R><K><K><T><P><K><S><K><G><A><S><T><P><A><A><S><T><L><P><T><A><N><G><A><R><P><A><R><S><G><T><A><L><S><G><P><D><A><P><P><N><G><P><L><Q><P><G><R><P><S><L><G><G><G><V><D><F><Y><D><V><A><F><K><V><M><L><V><G><D><S><G><V><G><K><T><C><L><L><V><R><F><K><D><G><A><F><L><A><G><T><F><I><S><T><V><G><I><D><F><R><N><K><V><L><D... | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsi... | Q9ULW5 |
Q13098 | CSN1_HUMAN | Protein MFH | Homo | <M><P><L><P><V><Q><V><F><N><L><Q><G><A><V><E><P><M><Q><I><D><V><D><P><Q><E><D><P><Q><N><A><P><D><V><N><Y><V><V><E><N><P><S><L><D><L><E><Q><Y><A><A><S><Y><S><G><L><M><R><I><E><R><L><Q><F><I><A><D><H><C><P><T><L><R><V><E><A><L><K><M><A><L><S><F><V><Q><R><T><F><N><V><D><M><Y><E><E><I><H><R><K><L><S><E><A><T><R><S><S><L><R... | Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease t... | Q13098 |
P84085 | ARF5_HUMAN | ADP-ribosylation factor 5 | Homo | <M><G><L><T><V><S><A><L><F><S><R><I><F><G><K><K><Q><M><R><I><L><M><V><G><L><D><A><A><G><K><T><T><I><L><Y><K><L><K><L><G><E><I><V><T><T><I><P><T><I><G><F><N><V><E><T><V><E><Y><K><N><I><C><F><T><V><W><D><V><G><G><Q><D><K><I><R><P><L><W><R><H><Y><F><Q><N><T><Q><G><L><I><F><V><V><D><S><N><D><R><E><R><V><Q><E><S><A><D><E><L... | (Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.<BOP> | P84085 |
C9JJH3 | U17LA_HUMAN | Ubiquitin carboxyl-terminal hydrolase 17-like protein 10 | Homo | <M><E><D><D><S><L><Y><L><G><G><E><W><Q><F><N><H><F><S><K><L><T><S><S><R><P><D><A><A><F><A><E><I><Q><R><T><S><L><P><E><K><S><P><L><S><C><E><T><R><V><D><L><C><D><D><L><A><P><V><A><R><Q><L><A><P><R><E><K><P><P><L><S><S><R><R><P><A><A><V><G><A><G><L><Q><N><M><G><N><T><C><Y><V><N><A><S><L><Q><C><L><T><Y><K><P><P><L><A><N><Y... | Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.<BOP> | C9JJH3 |
Q8NDF8 | PAPD5_HUMAN | Topoisomerase-related function protein 4-2 | Homo | <M><Y><R><S><G><E><R><L><L><G><S><H><A><L><P><A><E><Q><R><D><F><L><P><L><E><T><T><N><N><N><N><N><H><H><Q><P><G><A><W><A><R><R><A><G><S><S><A><S><S><P><P><S><A><S><S><S><P><H><P><S><A><A><V><P><A><A><D><P><A><D><S><A><S><G><S><S><N><K><R><K><R><D><N><K><A><S><G><G><R><A><A><G><G><G><R><A><D><G><G><G><V><V><Y><S><G><T><P... | Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation . Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA ... | Q8NDF8 |
Q9H0N0 | RAB6C_HUMAN | Rab6-like protein WTH3 | Homo | <M><S><A><G><G><D><F><G><N><P><L><R><K><F><K><L><V><F><L><G><E><Q><S><V><A><K><T><S><L><I><T><R><F><R><Y><D><S><F><D><N><T><Y><Q><A><I><I><G><I><D><F><L><S><K><T><M><Y><L><E><D><G><T><I><G><L><R><L><W><D><T><A><G><Q><E><R><L><R><S><L><I><P><R><Y><I><R><D><S><A><A><A><V><V><V><Y><D><I><T><N><V><N><S><F><Q><Q><T><T><K><W... | May be involved in the regulation of centrosome duplication and cell cycle progression.<BOP> | Q9H0N0 |
Q96AQ7 | CIDEC_HUMAN | Fat-specific protein FSP27 homolog | Homo | <M><E><Y><A><M><K><S><L><S><L><L><Y><P><K><S><L><S><R><H><V><S><V><R><T><S><V><V><T><Q><Q><L><L><S><E><P><S><P><K><A><P><R><A><R><P><C><R><V><S><T><A><D><R><S><V><R><K><G><I><M><A><Y><S><L><E><D><L><L><L><K><V><R><D><T><L><M><L><A><D><K><P><F><F><L><V><L><E><E><D><G><T><T><V><E><T><E><E><Y><F><Q><A><L><A><G><D><T><V><F... | Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference ... | Q96AQ7 |
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