accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q7Z3V5 | ZN571_HUMAN | Zinc finger protein 571 | Homo | <M><P><H><L><L><V><T><F><R><D><V><A><I><D><F><S><Q><E><E><W><E><C><L><D><P><A><Q><R><D><L><Y><R><D><V><M><L><E><N><Y><S><N><L><I><S><L><D><L><E><S><S><C><V><T><K><K><L><S><P><E><K><E><I><Y><E><M><E><S><L><Q><W><E><N><M><G><K><R><I><N><H><H><L><Q><Y><N><G><L><G><D><N><M><E><C><K><G><N><L><E><G><Q><E><A><S><Q><E><G><L><Y... | May be involved in transcriptional regulation.<BOP> | Q7Z3V5 |
Q9Y275 | TN13B_HUMAN | Tumor necrosis factor ligand superfamily member 13b, soluble form | Homo | <M><D><D><S><T><E><R><E><Q><S><R><L><T><S><C><L><K><K><R><E><E><M><K><L><K><E><C><V><S><I><L><P><R><K><E><S><P><S><V><R><S><S><K><D><G><K><L><L><A><A><T><L><L><L><A><L><L><S><C><C><L><T><V><V><S><F><Y><Q><V><A><A><L><Q><G><D><L><A><S><L><R><A><E><L><Q><G><H><H><A><E><K><L><P><A><G><A><G><A><P><K><A><G><L><E><E><A><P><A... | Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly reg... | Q9Y275 |
Q8IYK4 | GT252_HUMAN | Hydroxylysine galactosyltransferase 2 | Homo | <M><A><A><R><P><A><A><T><L><A><W><S><L><L><L><L><S><S><A><L><L><R><E><G><C><R><A><R><F><V><A><E><R><D><S><E><D><D><G><E><E><P><V><V><F><P><E><S><P><L><Q><S><P><T><V><L><V><A><V><L><A><R><N><A><A><H><T><L><P><H><F><L><G><C><L><E><R><L><D><Y><P><K><S><R><M><A><I><W><A><A><T><D><H><N><V><D><N><T><T><E><I><F><R><E><W><L><K... | Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen.<BOP> | Q8IYK4 |
Q9NRG9 | AAAS_HUMAN | Adracalin | Homo | <M><C><S><L><G><L><F><P><P><P><P><P><R><G><Q><V><T><L><Y><E><H><N><N><E><L><V><T><G><S><S><Y><E><S><P><P><P><D><F><R><G><Q><W><I><N><L><P><V><L><Q><L><T><K><D><P><L><K><T><P><G><R><L><D><H><G><T><R><T><A><F><I><H><H><R><E><Q><V><W><K><R><C><I><N><I><W><R><D><V><G><L><F><G><V><L><N><E><I><A><N><S><E><E><E><V><F><E><W><V... | Plays a role in the normal development of the peripheral and central nervous system . Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment .<BOP> | Q9NRG9 |
O95500 | CLD14_HUMAN | Claudin-14 | Homo | <M><A><S><T><A><V><Q><L><L><G><F><L><L><S><F><L><G><M><V><G><T><L><I><T><T><I><L><P><H><W><R><R><T><A><H><V><G><T><N><I><L><T><A><V><S><Y><L><K><G><L><W><M><E><C><V><W><H><S><T><G><I><Y><Q><C><Q><I><Y><R><S><L><L><A><L><P><Q><D><L><Q><A><A><R><A><L><M><V><I><S><C><L><L><S><G><I><A><C><A><C><A><V><I><G><M><K><C><T><R><C... | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.<BOP> | O95500 |
P11686 | PSPC_HUMAN | SP5 | Homo | <M><D><V><G><S><K><E><V><L><M><E><S><P><P><D><Y><S><A><A><P><R><G><R><F><G><I><P><C><C><P><V><H><L><K><R><L><L><I><V><V><V><V><V><V><L><I><V><V><V><I><V><G><A><L><L><M><G><L><H><M><S><Q><K><H><T><E><M><V><L><E><M><S><I><G><A><P><E><A><Q><Q><R><L><A><L><S><E><H><L><V><T><T><A><T><F><S><I><G><S><T><G><L><V><V><Y><D><Y><Q... | Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.<BOP> | P11686 |
Q495M3 | S36A2_HUMAN | Transmembrane domain rich protein 1 | Homo | <M><S><V><T><K><S><T><E><G><P><Q><G><A><V><A><I><K><L><D><L><M><S><P><P><E><S><A><K><K><L><E><N><K><D><S><T><F><L><D><E><S><P><S><E><S><A><G><L><K><K><T><K><G><I><T><V><F><Q><A><L><I><H><L><V><K><G><N><M><G><T><G><I><L><G><L><P><L><A><V><K><N><A><G><I><L><M><G><P><L><S><L><L><V><M><G><F><I><A><C><H><C><M><H><I><L><V><K... | Electrogenic proton/amino acid symporter with a high selectivity for the small side chains amino acids glycine, alanine and proline, where both L- and D-enantiomers are transported. Extension of the backbone length, as in beta-alanine and 4-aminobutanoate or methylation of the amino group, as in sarcosine and N,N-dimet... | Q495M3 |
Q99972 | MYOC_HUMAN | Myocilin 35 kDa N-terminal fragment | Homo | <M><R><F><F><C><A><R><C><C><S><F><G><P><E><M><P><A><V><Q><L><L><L><L><A><C><L><V><W><D><V><G><A><R><T><A><Q><L><R><K><A><N><D><Q><S><G><R><C><Q><Y><T><F><S><V><A><S><P><N><E><S><S><C><P><E><Q><S><Q><A><M><S><V><I><H><N><L><Q><R><D><S><S><T><Q><R><L><D><L><E><A><T><K><A><R><L><S><S><L><E><S><L><L><H><Q><L><T><L><D><Q><A... | Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-... | Q99972 |
Q9Y234 | LIPT_HUMAN | Lipoyl ligase | Homo | <M><L><I><P><F><S><M><K><N><C><F><Q><L><L><C><N><C><Q><V><P><A><A><G><F><K><K><T><V><K><N><G><L><I><L><Q><S><I><S><N><D><V><Y><Q><N><L><A><V><E><D><W><I><H><D><H><M><N><L><E><G><K><P><I><L><F><F><W><Q><N><S><P><S><V><V><I><G><R><H><Q><N><P><W><Q><E><C><N><L><N><L><M><R><E><E><G><I><K><L><A><R><R><R><S><G><G><G><T><V><Y... | Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes.<BOP> | Q9Y234 |
P48544 | KCNJ5_HUMAN | Potassium channel, inwardly rectifying subfamily J member 5 | Homo | <M><A><G><D><S><R><N><A><M><N><Q><D><M><E><I><G><V><T><P><W><D><P><K><K><I><P><K><Q><A><R><D><Y><V><P><I><A><T><D><R><T><R><L><L><A><E><G><K><K><P><R><Q><R><Y><M><E><K><S><G><K><C><N><V><H><H><G><N><V><Q><E><T><Y><R><Y><L><S><D><L><F><T><T><L><V><D><L><K><W><R><F><N><L><L><V><F><T><M><V><Y><T><V><T><W><L><F><F><G><F><I... | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the volt... | P48544 |
Q9Y2U2 | KCNK7_HUMAN | Potassium channel subfamily K member 7 | Homo | <M><G><G><L><R><P><W><S><R><Y><G><L><L><V><V><A><H><L><L><A><L><G><L><G><A><V><V><F><Q><A><L><E><G><P><P><A><C><R><L><Q><A><E><L><R><A><E><L><A><A><F><Q><A><E><H><R><A><C><L><P><P><G><A><L><E><E><L><L><G><T><A><L><A><T><Q><A><H><G><V><S><T><L><G><N><S><S><E><G><R><T><W><D><L><P><S><A><L><L><F><A><A><S><I><L><T><T><T><G... | Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.<BOP> | Q9Y2U2 |
Q02040 | AK17A_HUMAN | Splicing factor, arginine/serine-rich 17A | Homo | <M><A><A><A><T><I><V><H><D><T><S><E><A><V><E><L><C><P><A><Y><G><L><Y><L><K><P><I><T><K><M><T><I><S><V><A><L><P><Q><L><K><Q><P><G><K><S><I><S><N><W><E><V><M><E><R><L><K><G><M><V><Q><N><H><Q><F><S><T><L><R><I><S><K><S><T><M><D><F><I><R><F><E><G><E><V><E><N><K><S><L><V><K><S><F><L><A><C><L><D><G><K><T><I><K><L><S><G><F><S... | Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.<BOP> | Q02040 |
Q8TAG5 | VTM2A_HUMAN | V-set and transmembrane domain-containing protein 2A | Homo | <M><M><G><I><F><L><V><Y><V><G><F><V><F><F><S><V><L><Y><V><Q><Q><G><L><S><S><Q><A><K><F><T><E><F><P><R><N><V><T><A><T><E><G><Q><N><V><E><M><S><C><A><F><Q><S><G><S><A><S><V><Y><L><E><I><Q><W><W><F><L><R><G><P><E><D><L><D><P><G><A><E><G><A><G><A><Q><V><E><L><L><P><D><R><D><P><D><S><D><G><T><K><I><S><T><V><K><V><Q><G><N><D... | Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway.<BOP> | Q8TAG5 |
P32247 | BRS3_HUMAN | Bombesin receptor subtype-3 | Homo | <M><A><Q><R><Q><P><H><S><P><N><Q><T><L><I><S><I><T><N><D><T><E><S><S><S><S><V><V><S><N><D><N><T><N><K><G><W><S><G><D><N><S><P><G><I><E><A><L><C><A><I><Y><I><T><Y><A><V><I><I><S><V><G><I><L><G><N><A><I><L><I><K><V><F><F><K><T><K><S><M><Q><T><V><P><N><I><F><I><T><S><L><A><F><G><D><L><L><L><L><L><T><C><V><P><V><D><A><T><H... | Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.<BOP> | P32247 |
Q9UBU9 | NXF1_HUMAN | mRNA export factor TAP | Homo | <M><A><D><E><G><K><S><Y><S><E><H><D><D><E><R><V><N><F><P><Q><R><K><K><K><G><R><G><P><F><R><W><K><Y><G><E><G><N><R><R><S><G><R><G><G><S><G><I><R><S><S><R><L><E><E><D><D><G><D><V><A><M><S><D><A><Q><D><G><P><R><V><R><Y><N><P><Y><T><T><R><P><N><R><R><G><D><T><W><H><D><R><D><R><I><H><V><T><V><R><R><D><R><A><P><P><E><R><G><G... | Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway) . The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX com... | Q9UBU9 |
P78348 | ASIC1_HUMAN | Brain sodium channel 2 | Homo | <M><E><L><K><A><E><E><E><E><V><G><G><V><Q><P><V><S><I><Q><A><F><A><S><S><S><T><L><H><G><L><A><H><I><F><S><Y><E><R><L><S><L><K><R><A><L><W><A><L><C><F><L><G><S><L><A><V><L><L><C><V><C><T><E><R><V><Q><Y><Y><F><H><Y><H><H><V><T><K><L><D><E><V><A><A><S><Q><L><T><F><P><A><V><T><L><C><N><L><N><E><F><R><F><S><Q><V><S><K><N><D... | Isoform 1 does not display proton-gated cation channel activity.<BOP> | P78348 |
Q5UCC4 | EMC10_HUMAN | Hematopoietic signal peptide-containing membrane domain-containing protein 1 | Homo | <M><A><A><A><S><A><G><A><T><R><L><L><L><L><L><L><M><A><V><A><A><P><S><R><A><R><G><S><G><C><R><A><G><T><G><A><R><G><A><G><A><E><G><R><E><G><E><A><C><G><T><V><G><L><L><L><E><H><S><F><E><I><D><D><S><A><N><F><R><K><R><G><S><L><L><W><N><Q><Q><D><G><T><L><S><L><S><Q><R><Q><L><S><E><E><E><R><G><R><L><R><D><V><A><A><L><N><G><L... | Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins . Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such ... | Q5UCC4 |
Q9NPF4 | OSGEP_HUMAN | tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP | Homo | <M><P><A><V><L><G><F><E><G><S><A><N><K><I><G><V><G><V><V><R><D><G><K><V><L><A><N><P><R><R><T><Y><V><T><P><P><G><T><G><F><L><P><G><D><T><A><R><H><H><R><A><V><I><L><D><L><L><Q><E><A><L><T><E><S><G><L><T><S><Q><D><I><D><C><I><A><Y><T><K><G><P><G><M><G><A><P><L><V><S><V><A><V><V><A><R><T><V><A><Q><L><W><N><K><P><L><V><G><V... | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of... | Q9NPF4 |
Q8N162 | OR8H2_HUMAN | Olfactory receptor OR11-171 | Homo | <M><M><G><R><R><N><N><T><N><V><A><D><F><I><L><M><G><L><T><L><S><E><E><I><Q><M><A><L><F><M><L><F><L><L><I><Y><L><I><T><M><L><G><N><V><G><M><I><L><I><I><R><L><D><L><Q><L><H><T><P><M><Y><F><F><L><T><H><L><S><F><I><D><L><S><Y><S><T><V><V><T><P><K><T><L><A><N><L><L><T><S><N><Y><I><S><F><T><G><C><F><A><Q><M><F><F><F><A><F><L... | Odorant receptor.<BOP> | Q8N162 |
Q9UK99 | FBX3_HUMAN | F-box only protein 3 | Homo | <M><A><A><M><E><T><E><T><A><P><L><T><L><E><S><L><P><T><D><P><L><L><L><I><L><S><F><L><D><Y><R><D><L><I><N><C><C><Y><V><S><R><R><L><S><Q><L><S><S><H><D><P><L><W><R><R><H><C><K><K><Y><W><L><I><S><E><E><E><K><T><Q><K><N><Q><C><W><K><S><L><F><I><D><T><Y><S><D><V><G><R><Y><I><D><H><Y><A><A><I><K><K><A><W><D><D><L><K><K><Y><L... | Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and ... | Q9UK99 |
Q14314 | FGL2_HUMAN | pT49 | Homo | <M><K><L><A><N><W><Y><W><L><S><S><A><V><L><A><T><Y><G><F><L><V><V><A><N><N><E><T><E><E><I><K><D><E><R><A><K><D><V><C><P><V><R><L><E><S><R><G><K><C><E><E><A><G><E><C><P><Y><Q><V><S><L><P><P><L><T><I><Q><L><P><K><Q><F><S><R><I><E><E><V><F><K><E><V><Q><N><L><K><E><I><V><N><S><L><K><K><S><C><Q><D><C><K><L><Q><A><D><D><N><G... | May play a role in physiologic lymphocyte functions at mucosal sites.<BOP> | Q14314 |
Q02363 | ID2_HUMAN | Inhibitor of differentiation 2 | Homo | <M><K><A><F><S><P><V><R><S><V><R><K><N><S><L><S><D><H><S><L><G><I><S><R><S><K><T><P><V><D><D><P><M><S><L><L><Y><N><M><N><D><C><Y><S><K><L><K><E><L><V><P><S><I><P><Q><N><K><K><V><S><K><M><E><I><L><Q><H><V><I><D><Y><I><L><D><L><Q><I><A><L><D><S><H><P><T><I><V><S><L><H><H><Q><R><P><G><Q><N><Q><A><S><R><T><P><L><T><T><L><N... | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, se... | Q02363 |
Q9UKL0 | RCOR1_HUMAN | Protein CoREST | Homo | <M><P><A><M><V><E><K><G><P><E><V><S><G><K><R><R><G><R><N><N><A><A><A><S><A><S><A><A><A><A><S><A><A><A><S><A><A><C><A><S><P><A><A><T><A><A><S><G><A><A><A><S><S><A><S><A><A><A><A><S><A><A><A><A><P><N><N><G><Q><N><K><S><L><A><A><A><A><P><N><G><N><S><S><S><N><S><W><E><E><G><S><S><G><S><S><S><D><E><E><H><G><G><G><G><M><R><V... | Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC com... | Q9UKL0 |
Q969X6 | UTP4_HUMAN | UTP4 small subunit processome component | Homo | <M><G><E><F><K><V><H><R><V><R><F><F><N><Y><V><P><S><G><I><R><C><V><A><Y><N><N><Q><S><N><R><L><A><V><S><R><T><D><G><T><V><E><I><Y><N><L><S><A><N><Y><F><Q><E><K><F><F><P><G><H><E><S><R><A><T><E><A><L><C><W><A><E><G><Q><R><L><F><S><A><G><L><N><G><E><I><M><E><Y><D><L><Q><A><L><N><I><K><Y><A><M><D><A><F><G><G><P><I><W><S><M... | Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b. Required for optimal pre-ribosomal RNA transcription by RNA polymerase . May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which ... | Q969X6 |
Q9Y3A3 | PHOCN_HUMAN | Preimplantation protein 3 | Homo | <M><V><M><A><E><G><T><A><V><L><R><R><N><R><P><G><T><K><A><Q><D><F><Y><N><W><P><D><E><S><F><D><E><M><D><S><T><L><A><V><Q><Q><Y><I><Q><Q><N><I><R><A><D><C><S><N><I><D><K><I><L><E><P><P><E><G><Q><D><E><G><V><W><K><Y><E><H><L><R><Q><F><C><L><E><L><N><G><L><A><V><K><L><Q><S><E><C><H><P><D><T><C><T><Q><M><T><A><T><E><Q><W><I... | May play a role in membrane trafficking, specifically in membrane budding reactions.<BOP> | Q9Y3A3 |
Q3B820 | F161A_HUMAN | Protein FAM161A | Homo | <M><A><T><S><H><R><V><A><K><L><V><A><S><S><L><Q><T><P><V><N><P><I><T><G><A><R><V><A><Q><Y><E><R><E><D><P><L><K><A><L><A><A><A><E><A><I><L><E><D><E><E><E><E><K><V><A><Q><P><A><G><A><S><A><D><L><N><T><S><F><S><G><V><D><E><H><A><P><I><S><Y><E><D><F><V><N><F><P><D><I><H><H><S><N><E><E><Y><F><K><K><V><E><E><L><K><A><A><H><I... | Involved in ciliogenesis.<BOP> | Q3B820 |
Q92988 | DLX4_HUMAN | Homeobox protein DLX-8 | Homo | <M><T><S><L><P><C><P><L><P><G><R><D><A><S><K><A><V><F><P><D><L><A><P><V><P><S><V><A><A><A><Y><P><L><G><L><S><P><T><T><A><A><S><P><N><L><S><Y><S><R><P><Y><G><H><L><L><S><Y><P><Y><T><E><P><A><N><P><G><D><S><Y><L><S><C><Q><Q><P><A><A><L><S><Q><P><L><C><G><P><A><E><H><P><Q><E><L><E><A><D><S><E><K><P><R><L><S><P><E><P><S><E... | May play a role in determining the production of hemoglobin S. May act as a repressor. During embryonic development, plays a role in palatogenesis.<BOP> | Q92988 |
Q15758 | AAAT_HUMAN | Solute carrier family 1 member 5 | Homo | <M><V><A><D><P><P><R><D><S><K><G><L><A><A><A><E><P><T><A><N><G><G><L><A><L><A><S><I><E><D><Q><G><A><A><A><G><G><Y><C><G><S><R><D><Q><V><R><R><C><L><R><A><N><L><L><V><L><L><T><V><V><A><V><V><A><G><V><A><L><G><L><G><V><S><G><A><G><G><A><L><A><L><G><P><E><R><L><S><A><F><V><F><P><G><E><L><L><L><R><L><L><R><M><I><I><L><P><L... | (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses.<BOP> | Q15758 |
Q9UC07 | ZNF69_HUMAN | hZNF3 | Homo | <M><P><C><C><S><H><R><R><C><R><E><D><P><G><T><S><E><S><Q><E><M><D><P><V><A><F><D><D><V><A><V><N><F><T><Q><E><E><W><A><L><L><D><I><S><Q><R><K><L><Y><K><E><V><M><L><E><T><F><R><N><L><T><S><V><G><K><S><W><K><D><Q><N><I><E><Y><E><Y><Q><N><P><R><R><N><F><R><S><L><I><E><K><K><V><N><E><I><K><D><D><S><H><C><G><E><T><F><T><Q><V... | May be involved in transcriptional regulation.<BOP> | Q9UC07 |
Q8NH04 | O2T27_HUMAN | Olfactory receptor OR1-67 | Homo | <M><E><Q><S><N><Y><S><V><Y><A><D><F><I><L><L><G><L><F><S><N><A><R><F><P><W><L><L><F><A><L><I><L><L><V><F><L><T><S><I><A><S><N><V><V><K><I><I><L><I><H><I><D><S><R><L><H><T><P><M><Y><F><L><L><S><Q><L><S><L><R><D><I><L><Y><I><S><T><I><V><P><K><M><L><V><D><Q><V><M><S><Q><R><A><I><S><F><A><G><C><T><A><Q><H><F><L><Y><L><T><L... | Odorant receptor.<BOP> | Q8NH04 |
Q9Y3D0 | CIA2B_HUMAN | Protein FAM96B | Homo | <M><V><G><G><G><G><V><G><G><G><L><L><E><N><A><N><P><L><I><Y><Q><R><S><G><E><R><P><V><T><A><G><E><E><D><E><Q><V><P><D><S><I><D><A><R><E><I><F><D><L><I><R><S><I><N><D><P><E><H><P><L><T><L><E><E><L><N><V><V><E><Q><V><R><V><Q><V><S><D><P><E><S><T><V><A><V><A><F><T><P><T><I><P><H><C><S><M><A><T><L><I><G><L><S><I><K><V><K><L... | Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins . As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nucle... | Q9Y3D0 |
P11021 | BIP_HUMAN | Immunoglobulin heavy chain-binding protein | Homo | <M><K><L><S><L><V><A><A><M><L><L><L><L><S><A><A><R><A><E><E><E><D><K><K><E><D><V><G><T><V><V><G><I><D><L><G><T><T><Y><S><C><V><G><V><F><K><N><G><R><V><E><I><I><A><N><D><Q><G><N><R><I><T><P><S><Y><V><A><F><T><P><E><G><E><R><L><I><G><D><A><A><K><N><Q><L><T><S><N><P><E><N><T><V><F><D><A><K><R><L><I><G><R><T><W><N><D><P><S... | (Microbial infection) Acts as a receptor for CotH proteins expressed by fungi of the order mucorales, the causative agent of mucormycosis, which plays an important role in epithelial cell invasion by the fungi . Acts as a receptor for R.delemar CotH3 in nasal epithelial cells, which may be an early step in rhinoorbital... | P11021 |
P04066 | FUCO_HUMAN | Alpha-L-fucoside fucohydrolase 1 | Homo | <M><R><A><P><G><M><R><S><R><P><A><G><P><A><L><L><L><L><L><L><F><L><G><A><A><E><S><V><R><R><A><Q><P><P><R><R><Y><T><P><D><W><P><S><L><D><S><R><P><L><P><A><W><F><D><E><A><K><F><G><V><F><I><H><W><G><V><F><S><V><P><A><W><G><S><E><W><F><W><W><H><W><Q><G><E><G><R><P><Q><Y><Q><R><F><M><R><D><N><Y><P><P><G><F><S><Y><A><D><F><G... | Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.<BOP> | P04066 |
B2RXH4 | BTBDI_HUMAN | BTB/POZ domain-containing protein 18 | Homo | <M><C><S><P><A><S><P><K><I><L><Y><R><N><P><R><F><L><R><L><A><F><L><Q><L><H><H><Q><Q><Q><S><D><V><F><C><D><V><L><L><Q><A><E><G><E><A><V><P><A><H><C><C><I><L><S><A><C><S><P><F><F><T><E><R><L><E><R><E><R><P><A><Q><G><G><K><V><V><L><E><L><G><G><L><K><I><S><T><L><R><K><L><V><D><F><L><Y><T><S><E><M><E><V><S><Q><E><E><A><Q><D... | Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is ess... | B2RXH4 |
Q8IUB9 | KR191_HUMAN | High tyrosine-glycine keratin-associated protein 19.1 | Homo | <M><S><H><Y><G><S><Y><Y><G><G><L><G><Y><S><C><G><G><F><G><G><L><G><Y><G><Y><G><C><G><C><G><S><F><C><R><R><G><S><G><C><G><Y><G><G><Y><G><Y><G><S><G><F><G><S><Y><G><Y><G><S><G><F><G><G><Y><G><Y><G><S><G><F><G><G><Y><G><Y><G><C><C><R><P><S><Y><N><G><G><Y><G><F><S><G><F><Y> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q8IUB9 |
Q8NH59 | O51Q1_HUMAN | Olfactory receptor 51Q1 | Homo | <M><S><Q><V><T><N><T><T><Q><E><G><I><Y><F><I><L><T><D><I><P><G><F><E><A><S><H><I><W><I><S><I><P><V><C><C><L><Y><T><I><S><I><M><G><N><T><T><I><L><T><V><I><R><T><E><P><S><V><H><Q><R><M><Y><L><F><L><S><M><L><A><L><T><D><L><G><L><T><L><T><T><L><P><T><V><M><Q><L><L><W><F><N><V><R><R><I><S><S><E><A><C><F><A><Q><F><F><F><L><H... | Odorant receptor.<BOP> | Q8NH59 |
Q96EH8 | NEUL3_HUMAN | RING-type E3 ubiquitin transferase NEURL3 | Homo | <M><G><A><Q><L><C><F><E><A><N><A><K><A><P><R><E><A><L><R><F><H><A><E><A><K><G><A><Q><V><R><L><D><T><R><G><C><I><A><H><R><R><T><T><F><H><D><G><I><V><F><S><Q><R><P><V><R><L><G><E><R><V><A><L><R><V><L><R><E><E><S><G><W><C><G><G><L><R><V><G><F><T><R><L><D><P><A><C><V><S><V><P><S><L><P><P><F><L><C><P><D><L><E><E><Q><S><P><T... | E3 ubiquitin-protein ligase that plays a role in various biological processes such as lung development or innate immunity . Seems to utilize UBE2E1. Promotes innate antiviral response by catalyzing 'Lys-63'-linked ubiquitination of IRF7 . Inhibits also hepatitis C virus assembly by directly binding to viral E1 envelope... | Q96EH8 |
P19438 | TNR1A_HUMAN | Tumor necrosis factor-binding protein 1 | Homo | <M><G><L><S><T><V><P><D><L><L><L><P><L><V><L><L><E><L><L><V><G><I><Y><P><S><G><V><I><G><L><V><P><H><L><G><D><R><E><K><R><D><S><V><C><P><Q><G><K><Y><I><H><P><Q><N><N><S><I><C><C><T><K><C><H><K><G><T><Y><L><Y><N><D><C><P><G><P><G><Q><D><T><D><C><R><E><C><E><S><G><S><F><T><A><S><E><N><H><L><R><H><C><L><S><C><S><K><C><R><K... | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine... | P19438 |
Q9HAJ7 | SP30L_HUMAN | Sin3-associated protein p30-like | Homo | <M><N><G><F><S><T><E><E><D><S><R><E><G><P><P><A><A><P><A><A><A><A><P><G><Y><G><Q><S><C><C><L><I><E><D><G><E><R><C><V><R><P><A><G><N><A><S><F><S><K><R><V><Q><K><S><I><S><Q><K><K><L><K><L><D><I><D><K><S><V><R><H><L><Y><I><C><D><F><H><K><N><F><I><Q><S><V><R><N><K><R><K><R><K><T><S><D><D><G><G><D><S><P><E><H><D><T><D><I><P... | Functions as transcription repressor; its activity is marginally lower than that of isoform 1.<BOP> | Q9HAJ7 |
Q8NGL3 | OR5DE_HUMAN | Olfactory receptor OR11-150 | Homo | <M><M><M><V><L><R><N><L><S><M><E><P><T><F><A><L><L><G><F><T><D><Y><P><K><L><Q><I><P><L><F><L><V><F><L><L><M><Y><V><I><T><V><V><G><N><L><G><M><I><I><I><I><K><I><N><P><K><F><H><T><P><M><Y><F><F><L><S><H><L><S><F><V><D><F><C><Y><S><S><I><V><T><P><K><L><L><E><N><L><V><M><A><D><K><S><I><F><Y><F><S><C><M><M><Q><Y><F><L><S><C... | Odorant receptor.<BOP> | Q8NGL3 |
O43174 | CP26A_HUMAN | Retinoic acid-metabolizing cytochrome | Homo | <M><G><L><P><A><L><L><A><S><A><L><C><T><F><V><L><P><L><L><L><F><L><A><A><I><K><L><W><D><L><Y><C><V><S><G><R><D><R><S><C><A><L><P><L><P><P><G><T><M><G><F><P><F><F><G><E><T><L><Q><M><V><L><Q><R><R><K><F><L><Q><M><K><R><R><K><Y><G><F><I><Y><K><T><H><L><F><G><R><P><T><V><R><V><M><G><A><D><N><V><R><R><I><L><L><G><E><H><R><L... | A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, wit... | O43174 |
P36871 | PGM1_HUMAN | Glucose phosphomutase 1 | Homo | <M><V><K><I><V><T><V><K><T><Q><A><Y><Q><D><Q><K><P><G><T><S><G><L><R><K><R><V><K><V><F><Q><S><S><A><N><Y><A><E><N><F><I><Q><S><I><I><S><T><V><E><P><A><Q><R><Q><E><A><T><L><V><V><G><G><D><G><R><F><Y><M><K><E><A><I><Q><L><I><A><R><I><A><A><A><N><G><I><G><R><L><V><I><G><Q><N><G><I><L><S><T><P><A><V><S><C><I><I><R><K><I><K... | This enzyme participates in both the breakdown and synthesis of glucose.<BOP> | P36871 |
Q8IYG6 | LRC56_HUMAN | Leucine-rich repeat-containing protein 56 | Homo | <M><D><L><G><W><D><R><S><R><G><P><R><R><S><T><S><S><V><R><V><R><E><L><S><W><Q><G><L><H><N><P><C><P><Q><S><K><G><P><G><S><Q><R><D><R><L><G><E><Q><L><V><E><E><Y><L><S><P><A><R><L><Q><A><L><A><R><V><D><D><L><R><L><V><R><T><L><E><M><C><V><D><T><R><E><G><S><L><G><N><F><G><V><H><L><P><N><L><D><Q><L><K><L><N><G><S><H><L><G><S... | Required for the assembly of dynein arms.<BOP> | Q8IYG6 |
Q8N883 | ZN614_HUMAN | Zinc finger protein 614 | Homo | <M><I><K><T><Q><E><S><L><T><L><E><D><V><A><V><E><F><S><W><E><E><W><Q><L><L><D><T><A><Q><K><N><L><Y><R><D><V><M><V><E><N><Y><N><H><L><V><S><L><G><Y><Q><T><S><K><P><D><V><L><S><K><L><A><H><G><Q><E><P><W><T><T><D><A><K><I><Q><N><K><N><C><P><G><I><G><K><V><D><S><H><L><Q><E><H><S><P><N><Q><R><L><L><K><S><V><Q><Q><C><N><G><Q... | May be involved in transcriptional regulation.<BOP> | Q8N883 |
Q8IUR0 | TPPC5_HUMAN | Trafficking protein particle complex subunit 5 | Homo | <M><E><A><R><F><T><R><G><K><S><A><L><L><E><R><A><L><A><R><P><R><T><E><V><S><L><S><A><F><A><L><L><F><S><E><L><V><Q><H><C><Q><S><R><V><F><S><V><A><E><L><Q><S><R><L><A><A><L><G><R><Q><V><G><A><R><V><L><D><A><L><V><A><R><E><K><G><A><R><R><E><T><K><V><L><G><A><L><L><F><V><K><G><A><V><W><K><A><L><F><G><K><E><A><D><K><L><E><Q... | May play a role in vesicular transport from endoplasmic reticulum to Golgi.<BOP> | Q8IUR0 |
A6NFH5 | FBP12_HUMAN | Fatty acid-binding protein 12 | Homo | <M><I><D><Q><L><Q><G><T><W><K><S><I><S><C><E><N><S><E><D><Y><M><K><E><L><G><I><G><R><A><S><R><K><L><G><R><L><A><K><P><T><V><T><I><S><T><D><G><D><V><I><T><I><K><T><K><S><I><F><K><N><N><E><I><S><F><K><L><G><E><E><F><E><E><I><T><P><G><G><H><K><T><K><S><K><V><T><L><D><K><E><S><L><I><Q><V><Q><D><W><D><G><K><E><T><T><I><T><R... | May play a role in lipid transport.<BOP> | A6NFH5 |
Q9NYV9 | T2R13_HUMAN | Taste receptor family B member 3 | Homo | <M><E><S><A><L><P><S><I><F><T><L><V><I><I><A><E><F><I><I><G><N><L><S><N><G><F><I><V><L><I><N><C><I><D><W><V><S><K><R><E><L><S><S><V><D><K><L><L><I><I><L><A><I><S><R><I><G><L><I><W><E><I><L><V><S><W><F><L><A><L><H><Y><L><A><I><F><V><S><G><T><G><L><R><I><M><I><F><S><W><I><V><S><N><H><F><N><L><W><L><A><T><I><F><S><I><F><Y... | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.<BOP> | Q9NYV9 |
Q08431 | MFGM_HUMAN | Medin | Homo | <M><P><R><P><R><L><L><A><A><L><C><G><A><L><L><C><A><P><S><L><L><V><A><L><D><I><C><S><K><N><P><C><H><N><G><G><L><C><E><E><I><S><Q><E><V><R><G><D><V><F><P><S><Y><T><C><T><C><L><K><G><Y><A><G><N><H><C><E><T><K><C><V><E><P><L><G><L><E><N><G><N><I><A><N><S><Q><I><A><A><S><S><V><R><V><T><F><L><G><L><Q><H><W><V><P><E><L><A><R... | Main constituent of aortic medial amyloid.<BOP> | Q08431 |
Q96QD9 | UIF_HUMAN | Forty-two-three domain-containing protein 1 | Homo | <M><N><R><F><G><T><R><L><V><G><A><T><A><T><S><S><P><P><P><K><A><R><S><N><E><N><L><D><K><I><D><M><S><L><D><D><I><I><K><L><N><R><K><E><G><K><K><Q><N><F><P><R><L><N><R><R><L><L><Q><Q><S><G><A><Q><Q><F><R><M><R><V><R><W><G><I><Q><Q><N><S><G><F><G><K><T><S><L><N><R><R><G><R><V><M><P><G><K><R><R><P><N><G><V><I><T><G><L><A><A... | Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4.<BOP> | Q96QD9 |
Q30201 | HFE_HUMAN | HLA-H | Homo | <M><G><P><R><A><R><P><A><L><L><L><L><M><L><L><Q><T><A><V><L><Q><G><R><L><L><R><S><H><S><L><H><Y><L><F><M><G><A><S><E><Q><D><L><G><L><S><L><F><E><A><L><G><Y><V><D><D><Q><L><F><V><F><Y><D><H><E><S><R><R><V><E><P><R><T><P><W><V><S><S><R><I><S><S><Q><M><W><L><Q><L><S><Q><S><L><K><G><W><D><H><M><F><T><V><D><F><W><T><I><M><E... | Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.<BOP> | Q30201 |
Q13126 | MTAP_HUMAN | 5'-methylthioadenosine phosphorylase | Homo | <M><A><S><G><T><T><T><T><A><V><K><I><G><I><I><G><G><T><G><L><D><D><P><E><I><L><E><G><R><T><E><K><Y><V><D><T><P><F><G><K><P><S><D><A><L><I><L><G><K><I><K><N><V><D><C><V><L><L><A><R><H><G><R><Q><H><T><I><M><P><S><K><V><N><Y><Q><A><N><I><W><A><L><K><E><E><G><C><T><H><V><I><V><T><T><A><C><G><S><L><R><E><E><I><Q><P><G><D><I... | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethioni... | Q13126 |
A8MW95 | BECN2_HUMAN | Beclin-1-like protein 1 | Homo | <M><S><S><I><R><F><L><C><Q><R><C><H><Q><A><L><K><L><S><G><S><S><E><S><R><S><L><P><A><A><P><A><P><T><S><G><Q><A><E><P><G><D><T><R><E><P><G><V><T><T><R><E><V><T><D><A><E><E><Q><Q><D><G><A><S><S><R><S><P><P><G><D><G><S><V><S><K><G><H><A><N><I><F><T><L><L><G><E><L><G><A><M><H><M><L><S><S><I><Q><K><A><A><G><D><I><F><D><I><V... | Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.<BOP> | A8MW95 |
Q8NBQ5 | DHB11_HUMAN | Short chain dehydrogenase/reductase family 16C member 2 | Homo | <M><K><F><L><L><D><I><L><L><L><L><P><L><L><I><V><C><S><L><E><S><F><V><K><L><F><I><P><K><R><R><K><S><V><T><G><E><I><V><L><I><T><G><A><G><H><G><I><G><R><L><T><A><Y><E><F><A><K><L><K><S><K><L><V><L><W><D><I><N><K><H><G><L><E><E><T><A><A><K><C><K><G><L><G><A><K><V><H><T><F><V><V><D><C><S><N><R><E><D><I><Y><S><S><A><K><K><V... | Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroe... | Q8NBQ5 |
Q8IWL1 | SFPA2_HUMAN | Collectin-5 | Homo | <M><W><L><C><P><L><A><L><T><L><I><L><M><A><A><S><G><A><A><C><E><V><K><D><V><C><V><G><S><P><G><I><P><G><T><P><G><S><H><G><L><P><G><R><D><G><R><D><G><V><K><G><D><P><G><P><P><G><P><M><G><P><P><G><E><T><P><C><P><P><G><N><N><G><L><P><G><A><P><G><V><P><G><E><R><G><E><K><G><E><A><G><E><R><G><P><P><G><L><P><A><H><L><D><E><E><L... | In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.<BOP> | Q8IWL1 |
Q9UNF1 | MAGD2_HUMAN | MAGE-D2 antigen | Homo | <M><S><D><T><S><E><S><G><A><G><L><T><R><F><Q><A><E><A><S><E><K><D><S><S><S><M><M><Q><T><L><L><T><V><T><Q><N><V><E><V><P><E><T><P><K><A><S><K><A><L><E><V><S><E><D><V><K><V><S><K><A><S><G><V><S><K><A><T><E><V><S><K><T><P><E><A><R><E><A><P><A><T><Q><A><S><S><T><T><Q><L><T><D><T><Q><V><L><A><A><E><N><K><S><L><A><A><D><T><K... | Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule.<BOP> | Q9UNF1 |
P02787 | TRFE_HUMAN | Siderophilin | Homo | <M><R><L><A><V><G><A><L><L><V><C><A><V><L><G><L><C><L><A><V><P><D><K><T><V><R><W><C><A><V><S><E><H><E><A><T><K><C><Q><S><F><R><D><H><M><K><S><V><I><P><S><D><G><P><S><V><A><C><V><K><K><A><S><Y><L><D><C><I><R><A><I><A><A><N><E><A><D><A><V><T><L><D><A><G><L><V><Y><D><A><Y><L><A><P><N><N><L><K><P><V><V><A><E><F><Y><G><S><K... | (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use.<BOP> | P02787 |
Q9NR80 | ARHG4_HUMAN | APC-stimulated guanine nucleotide exchange factor 1 | Homo | <M><P><W><E><E><P><A><G><E><K><P><S><C><S><H><S><Q><K><A><F><H><M><E><P><A><Q><K><P><C><F><T><T><D><M><V><T><W><A><L><L><C><I><S><A><E><T><V><R><G><E><A><P><S><Q><P><R><G><I><P><H><R><S><P><V><S><V><D><D><L><W><L><E><K><T><Q><R><K><K><L><Q><K><Q><A><H><V><E><R><R><L><H><I><G><A><V><H><K><D><G><V><K><C><W><R><K><T><I><I... | Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorect... | Q9NR80 |
Q9BYR8 | KRA31_HUMAN | Keratin-associated protein 3.1 | Homo | <M><Y><C><C><A><L><R><S><C><S><V><P><T><G><P><A><T><T><F><C><S><F><D><K><S><C><R><C><G><V><C><L><P><S><T><C><P><H><E><I><S><L><L><Q><P><I><C><C><D><T><C><P><P><P><C><C><K><P><D><T><Y><V><P><T><C><W><L><L><N><N><C><H><P><T><P><G><L><S><G><I><N><L><T><T><Y><V><Q><P><G><C><E><S><P><C><E><P><R><C> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q9BYR8 |
P39748 | FEN1_HUMAN | Maturation factor 1 | Homo | <M><G><I><Q><G><L><A><K><L><I><A><D><V><A><P><S><A><I><R><E><N><D><I><K><S><Y><F><G><R><K><V><A><I><D><A><S><M><S><I><Y><Q><F><L><I><A><V><R><Q><G><G><D><V><L><Q><N><E><E><G><E><T><T><S><H><L><M><G><M><F><Y><R><T><I><R><M><M><E><N><G><I><K><P><V><Y><V><F><D><G><K><P><P><Q><L><K><S><G><E><L><A><K><R><S><E><R><R><A><E><A... | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It ente... | P39748 |
Q86TJ2 | TAD2B_HUMAN | ADA2-like protein beta | Homo | <M><A><E><L><G><K><K><Y><C><V><Y><C><L><A><E><V><S><P><L><R><F><R><C><T><E><C><Q><D><I><E><L><C><P><E><C><F><S><A><G><A><E><I><G><H><H><R><R><Y><H><G><Y><Q><L><V><D><G><G><R><F><T><L><W><G><P><E><A><E><G><G><W><T><S><R><E><E><Q><L><L><L><D><A><I><E><Q><F><G><F><G><N><W><E><D><M><A><A><H><V><G><A><S><R><T><P><Q><E><V><M... | Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2.<BOP> | Q86TJ2 |
P01568 | IFN21_HUMAN | Interferon alpha-F | Homo | <M><A><L><S><F><S><L><L><M><A><V><L><V><L><S><Y><K><S><I><C><S><L><G><C><D><L><P><Q><T><H><S><L><G><N><R><R><A><L><I><L><L><A><Q><M><G><R><I><S><P><F><S><C><L><K><D><R><H><D><F><G><F><P><Q><E><E><F><D><G><N><Q><F><Q><K><A><Q><A><I><S><V><L><H><E><M><I><Q><Q><T><F><N><L><F><S><T><K><D><S><S><A><T><W><E><Q><S><L><L><E><K... | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.<BOP> | P01568 |
Q8NI37 | PPTC7_HUMAN | T-cell activation protein phosphatase 2C-like | Homo | <M><F><S><V><L><S><Y><G><R><L><V><A><R><A><V><L><G><G><L><S><Q><T><D><P><R><A><G><G><G><G><G><G><D><Y><G><L><V><T><A><G><C><G><F><G><K><D><F><R><K><G><L><L><K><K><G><A><C><Y><G><D><D><A><C><F><V><A><R><H><R><S><A><D><V><L><G><V><A><D><G><V><G><G><W><R><D><Y><G><V><D><P><S><Q><F><S><G><T><L><M><R><T><C><E><R><L><V><K><E... | Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q . Dephosphorylates the ubiquinone biosynthesis protein COQ7 which is likely to lead to its activation .<BOP> | Q8NI37 |
P55774 | CCL18_HUMAN | CCL18(4-69) | Homo | <M><K><G><L><A><A><A><L><L><V><L><V><C><T><M><A><L><C><S><C><A><Q><V><G><T><N><K><E><L><C><C><L><V><Y><T><S><W><Q><I><P><Q><K><F><I><V><D><Y><S><E><T><S><P><Q><C><P><K><P><G><V><I><L><L><T><K><R><G><R><Q><I><C><A><D><P><N><K><K><W><V><Q><K><Y><I><S><D><L><K><L><N><A> | Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and th... | P55774 |
Q8NGG1 | OR8J2_HUMAN | Olfactory receptor 8J2 | Homo | <M><A><S><G><N><L><T><W><V><T><E><F><I><L><V><G><V><S><D><D><P><E><L><Q><I><P><L><F><L><V><F><L><V><L><Y><L><L><T><V><A><G><N><L><G><I><I><T><L><T><S><V><D><P><Q><L><Q><T><P><M><Y><F><F><L><R><H><L><A><I><I><N><L><C><N><S><T><V><V><A><P><K><M><L><V><N><F><L><V><T><K><K><T><I><S><Y><Y><G><C><A><A><Q><L><G><G><F><L><V><F... | Odorant receptor.<BOP> | Q8NGG1 |
Q7Z4H3 | HDDC2_HUMAN | Hepatitis C virus NS5A-transactivated protein 2 | Homo | <M><A><S><V><S><S><A><T><F><S><G><H><G><A><R><S><L><L><Q><F><L><R><L><V><G><Q><L><K><R><V><P><R><T><G><W><V><Y><R><N><V><Q><R><P><E><S><V><S><D><H><M><Y><R><M><A><V><M><A><M><V><I><K><D><D><R><L><N><K><D><R><C><V><R><L><A><L><V><H><D><M><A><E><C><I><V><G><D><I><A><P><A><D><N><I><P><K><E><E><K><H><R><R><E><E><E><A><M><K... | Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).<BOP> | Q7Z4H3 |
P31371 | FGF9_HUMAN | Heparin-binding growth factor 9 | Homo | <M><A><P><L><G><E><V><G><N><Y><F><G><V><Q><D><A><V><P><F><G><N><V><P><V><L><P><V><D><S><P><V><L><L><S><D><H><L><G><Q><S><E><A><G><G><L><P><R><G><P><A><V><T><D><L><D><H><L><K><G><I><L><R><R><R><Q><L><Y><C><R><T><G><F><H><L><E><I><F><P><N><G><T><I><Q><G><T><R><K><D><H><S><R><F><G><I><L><E><F><I><S><I><A><V><G><L><V><S><I... | Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cell... | P31371 |
Q2MKA7 | RSPO1_HUMAN | Roof plate-specific spondin-1 | Homo | <M><R><L><G><L><C><V><V><A><L><V><L><S><W><T><H><L><T><I><S><S><R><G><I><K><G><K><R><Q><R><R><I><S><A><E><G><S><Q><A><C><A><K><G><C><E><L><C><S><E><V><N><G><C><L><K><C><S><P><K><L><F><I><L><L><E><R><N><D><I><R><Q><V><G><V><C><L><P><S><C><P><P><G><Y><F><D><A><R><N><P><D><M><N><K><C><I><K><C><K><I><E><H><C><E><A><C><F><S... | Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors . Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expres... | Q2MKA7 |
Q8NGT0 | O13C9_HUMAN | Olfactory receptor OR9-13 | Homo | <M><E><W><E><N><Q><T><I><L><V><E><F><F><L><K><G><H><S><V><H><P><R><L><E><L><L><F><F><V><L><I><F><I><M><Y><V><V><I><L><L><G><N><G><T><L><I><L><I><S><I><L><D><P><H><L><H><T><P><M><Y><F><F><L><G><N><L><S><F><L><D><I><C><Y><T><T><T><S><I><P><S><T><L><V><S><F><L><S><E><R><K><T><I><S><F><S><G><C><A><V><Q><M><F><L><G><L><A><M... | Odorant receptor.<BOP> | Q8NGT0 |
Q6ZRF8 | RN207_HUMAN | RING finger protein 207 | Homo | <M><S><G><A><I><F><G><P><L><E><G><P><S><S><L><D><A><P><S><I><H><P><L><V><C><P><L><C><H><V><Q><Y><E><R><P><C><L><L><D><C><F><H><D><F><C><A><G><C><L><R><G><R><A><T><D><G><R><L><T><C><P><L><C><Q><H><Q><T><V><L><K><G><P><S><G><L><P><P><V><D><R><L><L><Q><F><L><V><D><S><S><G><D><G><V><E><A><V><R><C><A><N><C><D><L><E><C><S><E... | Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.<BOP> | Q6ZRF8 |
Q8WTU0 | DDI1_HUMAN | Protein DDI1 homolog 1 | Homo | <M><L><I><T><V><Y><C><V><R><R><D><L><S><E><V><T><F><S><L><Q><V><S><P><D><F><E><L><R><N><F><K><V><L><C><E><A><E><S><R><V><P><V><E><E><I><Q><I><I><H><M><E><R><L><L><I><E><D><H><C><S><L><G><S><Y><G><L><K><D><G><D><I><V><V><L><L><Q><K><D><N><V><G><P><R><A><P><G><R><A><P><N><Q><P><R><V><D><F><S><G><I><A><V><P><G><T><S><S><S... | Probable aspartic protease (Probable). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable). Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progr... | Q8WTU0 |
P03886 | NU1M_HUMAN | NADH dehydrogenase subunit 1 | Homo | <M><P><M><A><N><L><L><L><L><I><V><P><I><L><I><A><M><A><F><L><M><L><T><E><R><K><I><L><G><Y><M><Q><L><R><K><G><P><N><V><V><G><P><Y><G><L><L><Q><P><F><A><D><A><M><K><L><F><T><K><E><P><L><K><P><A><T><S><T><I><T><L><Y><I><T><A><P><T><L><A><L><T><I><A><L><L><L><W><T><P><L><P><M><P><N><P><L><V><N><L><N><L><G><L><L><F><I><L><A... | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for the catalytic activity and assembly of complex I .<BOP> | P03886 |
Q16671 | AMHR2_HUMAN | MIS type II receptor | Homo | <M><L><G><S><L><G><L><W><A><L><L><P><T><A><V><E><A><P><P><N><R><R><T><C><V><F><F><E><A><P><G><V><R><G><S><T><K><T><L><G><E><L><L><D><T><G><T><E><L><P><R><A><I><R><C><L><Y><S><R><C><C><F><G><I><W><N><L><T><Q><D><R><A><Q><V><E><M><Q><G><C><R><D><S><D><E><P><G><C><E><S><L><H><C><D><P><S><P><R><A><H><P><S><P><G><S><T><L><F... | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.<BOP> | Q16671 |
Q53EU6 | GPAT3_HUMAN | MAG-1 | Homo | <M><E><G><A><E><L><A><G><K><I><L><S><T><W><L><T><L><V><L><G><F><I><L><L><P><S><V><F><G><V><S><L><G><I><S><E><I><Y><M><K><I><L><V><K><T><L><E><W><A><T><I><R><I><E><K><G><T><P><K><E><S><I><L><K><N><S><A><S><V><G><I><I><Q><R><D><E><S><P><M><E><K><G><L><S><G><L><R><G><R><D><F><E><L><S><D><V><F><Y><F><S><K><K><G><L><E><A><I... | Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone . Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the g... | Q53EU6 |
P07550 | ADRB2_HUMAN | Beta-2 adrenoreceptor | Homo | <M><G><Q><P><G><N><G><S><A><F><L><L><A><P><N><G><S><H><A><P><D><H><D><V><T><Q><E><R><D><E><V><W><V><V><G><M><G><I><V><M><S><L><I><V><L><A><I><V><F><G><N><V><L><V><I><T><A><I><A><K><F><E><R><L><Q><T><V><T><N><Y><F><I><T><S><L><A><C><A><D><L><V><M><G><L><A><V><V><P><F><G><A><A><H><I><L><M><K><M><W><T><F><G><N><F><W><C><E... | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.<BOP> | P07550 |
Q9P0U4 | CXXC1_HUMAN | PHD finger and CXXC domain-containing protein 1 | Homo | <M><E><G><D><G><S><D><P><E><P><P><D><A><G><E><D><S><K><S><E><N><G><E><N><A><P><I><Y><C><I><C><R><K><P><D><I><N><C><F><M><I><G><C><D><N><C><N><E><W><F><H><G><D><C><I><R><I><T><E><K><M><A><K><A><I><R><E><W><Y><C><R><E><C><R><E><K><D><P><K><L><E><I><R><Y><R><H><K><K><S><R><E><R><D><G><N><E><R><D><S><S><E><P><R><D><E><G><G... | Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<BOP> | Q9P0U4 |
P31941 | ABC3A_HUMAN | Phorbolin-1 | Homo | <M><E><A><S><P><A><S><G><P><R><H><L><M><D><P><H><I><F><T><S><N><F><N><N><G><I><G><R><H><K><T><Y><L><C><Y><E><V><E><R><L><D><N><G><T><S><V><K><M><D><Q><H><R><G><F><L><H><N><Q><A><K><N><L><L><C><G><F><Y><G><R><H><A><E><L><R><F><L><D><L><V><P><S><L><Q><L><D><P><A><Q><I><Y><R><V><T><W><F><I><S><W><S><P><C><F><S><W><G><C><A... | DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targe... | P31941 |
Q7Z419 | R144B_HUMAN | p53-inducible RING finger protein | Homo | <M><G><S><A><G><R><L><H><Y><L><A><M><T><A><E><N><P><T><P><G><D><L><A><P><A><P><L><I><T><C><K><L><C><L><C><E><Q><S><L><D><K><M><T><T><L><Q><E><C><Q><C><I><F><C><T><A><C><L><K><Q><Y><M><Q><L><A><I><R><E><G><C><G><S><P><I><T><C><P><D><M><V><C><L><N><H><G><T><L><Q><E><A><E><I><A><C><L><V><P><V><D><Q><F><Q><L><Y><Q><R><L><K... | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent m... | Q7Z419 |
P51617 | IRAK1_HUMAN | Interleukin-1 receptor-associated kinase 1 | Homo | <M><A><G><G><P><G><P><G><E><P><A><A><P><G><A><Q><H><F><L><Y><E><V><P><P><W><V><M><C><R><F><Y><K><V><M><D><A><L><E><P><A><D><W><C><Q><F><A><A><L><I><V><R><D><Q><T><E><L><R><L><C><E><R><S><G><Q><R><T><A><S><V><L><W><P><W><I><N><R><N><A><R><V><A><D><L><V><H><I><L><T><H><L><Q><L><L><R><A><R><D><I><I><T><A><W><H><P><P><A><P... | Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phospho... | P51617 |
Q05932 | FOLC_HUMAN | Tetrahydrofolylpolyglutamate synthase | Homo | <M><S><R><A><R><S><H><L><R><A><A><L><F><L><A><A><A><S><A><R><G><I><T><T><Q><V><A><A><R><R><G><L><S><A><W><P><V><P><Q><E><P><S><M><E><Y><Q><D><A><V><R><M><L><N><T><L><Q><T><N><A><G><Y><L><E><Q><V><K><R><Q><R><G><D><P><Q><T><Q><L><E><A><M><E><L><Y><L><A><R><S><G><L><Q><V><E><D><L><D><R><L><N><I><I><H><V><T><G><T><K><G><K... | Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidin... | Q05932 |
Q9BYQ4 | KRA92_HUMAN | Ultrahigh sulfur keratin-associated protein 9.2 | Homo | <M><T><H><C><C><S><P><C><C><Q><P><T><C><C><R><T><T><C><C><R><T><T><C><W><K><P><T><T><V><T><T><C><S><S><T><P><C><C><Q><P><A><C><C><V><S><S><C><C><Q><P><C><C><R><P><T><C><C><Q><N><T><C><C><R><T><T><C><C><Q><P><T><C><V><T><S><C><C><Q><P><S><C><C><S><T><P><C><C><Q><P><T><C><C><G><S><S><C><C><G><Q><T><S><C><G><S><S><C><G><Q... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q9BYQ4 |
Q9NZ63 | TLS1_HUMAN | Hepatocellular carcinoma-associated antigen 59 | Homo | <M><P><V><V><R><K><I><F><R><R><R><R><G><D><S><E><S><E><E><D><E><Q><D><S><E><E><V><R><L><K><L><E><E><T><R><E><V><Q><N><L><R><K><R><P><N><G><V><S><A><V><A><L><L><V><G><E><K><V><Q><E><E><T><T><L><V><D><D><P><F><Q><M><K><T><G><G><M><V><D><M><K><K><L><K><E><R><G><K><D><K><I><S><E><E><E><D><L><H><L><G><T><S><F><S><A><E><T><N... | Involved in the regulation of telomeric heterochromatin assembly and control of telomere length.<BOP> | Q9NZ63 |
P56182 | RRP1_HUMAN | RRP1-like protein | Homo | <M><V><S><R><V><Q><L><P><P><E><I><Q><L><A><Q><R><L><A><G><N><E><Q><V><T><R><D><R><A><V><R><K><L><R><K><Y><I><V><A><R><T><Q><R><A><A><G><G><F><T><H><D><E><L><L><K><V><W><K><G><L><F><Y><C><M><W><M><Q><D><K><P><L><L><Q><E><E><L><G><R><T><I><S><Q><L><V><H><A><F><Q><T><T><E><A><Q><H><L><F><L><Q><A><F><W><Q><T><M><N><R><E><W... | Plays a critical role in the generation of 28S rRNA.<BOP> | P56182 |
Q5RKV6 | EXOS6_HUMAN | p11 | Homo | <M><P><G><D><H><R><R><I><R><G><P><E><E><S><Q><P><P><Q><L><Y><A><A><D><E><E><E><A><P><G><T><R><D><P><T><R><L><R><P><V><Y><A><R><A><G><L><L><S><Q><A><K><G><S><A><Y><L><E><A><G><G><T><K><V><L><C><A><V><S><G><P><R><Q><A><E><G><G><E><R><G><G><G><P><A><G><A><G><G><E><A><P><A><A><L><R><G><R><L><L><C><D><F><R><R><A><P><F><A><G... | Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the eliminatio... | Q5RKV6 |
O60762 | DPM1_HUMAN | Mannose-P-dolichol synthase subunit 1 | Homo | <M><A><S><L><E><V><S><R><S><P><R><R><S><R><R><E><L><E><V><R><S><P><R><Q><N><K><Y><S><V><L><L><P><T><Y><N><E><R><E><N><L><P><L><I><V><W><L><L><V><K><S><F><S><E><S><G><I><N><Y><E><I><I><I><I><D><D><G><S><P><D><G><T><R><D><V><A><E><Q><L><E><K><I><Y><G><S><D><R><I><L><L><R><P><R><E><K><K><L><G><L><G><T><A><Y><I><H><G><M><K... | Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) syn... | O60762 |
Q8NG81 | OR2M7_HUMAN | Olfactory receptor OR1-58 | Homo | <M><A><W><E><N><Q><T><F><N><S><D><F><L><L><L><G><I><F><N><H><S><P><T><H><T><F><L><F><F><L><V><L><A><I><F><S><V><A><F><M><G><N><S><I><M><V><L><L><I><Y><L><D><T><Q><L><H><T><P><M><Y><F><L><L><S><Q><L><S><L><M><D><L><M><L><I><C><T><T><V><P><K><M><A><F><N><Y><L><S><G><S><K><S><I><S><M><A><G><C><A><T><Q><I><F><F><Y><I><S><L... | Odorant receptor.<BOP> | Q8NG81 |
O95969 | SG1D2_HUMAN | Lipophilin-B | Homo | <M><K><L><S><V><C><L><L><L><V><T><L><A><L><C><C><Y><Q><A><N><A><E><F><C><P><A><L><V><S><E><L><L><D><F><F><F><I><S><E><P><L><F><K><L><S><L><A><K><F><D><A><P><P><E><A><V><A><A><K><L><G><V><K><R><C><T><D><Q><M><S><L><Q><K><R><S><L><I><A><E><V><L><V><K><I><L><K><K><C><S><V> | May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.<BOP> | O95969 |
Q8NFQ8 | TOIP2_HUMAN | Lumenal domain-like LAP1 | Homo | <M><A><D><S><G><L><R><E><P><Q><E><D><S><Q><K><D><L><E><N><D><P><S><V><N><S><Q><A><Q><E><T><T><I><I><A><S><N><A><E><E><A><E><I><L><H><S><A><C><G><L><S><K><D><H><Q><E><V><E><T><E><G><P><E><S><A><D><T><G><D><K><S><E><S><P><D><E><A><N><V><G><K><H><P><K><D><K><T><E><D><E><N><K><Q><S><F><L><D><G><G><K><G><H><H><L><P><S><E><N... | Required for endoplasmic reticulum integrity. Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TOR1A, TOR1B and TOR3A ATPase activity.<BOP> | Q8NFQ8 |
Q9NQT6 | FSCN3_HUMAN | Testis fascin | Homo | <M><D><E><T><E><W><I><H><R><H><P><K><A><E><D><L><R><V><G><L><I><S><W><A><G><T><Y><L><T><F><E><A><C><K><N><T><V><T><A><T><A><K><S><L><G><R><R><Q><T><W><E><I><L><V><S><N><E><H><E><T><Q><A><V><V><R><L><K><S><V><Q><G><L><Y><L><L><C><E><C><D><G><T><V><C><Y><G><R><P><R><T><S><H><H><G><C><F><L><L><R><F><H><R><N><S><K><W><T><L... | Acts as an actin bundling protein.<BOP> | Q9NQT6 |
P62993 | GRB2_HUMAN | SH2/SH3 adapter GRB2 | Homo | <M><E><A><I><A><K><Y><D><F><K><A><T><A><D><D><E><L><S><F><K><R><G><D><I><L><K><V><L><N><E><E><C><D><Q><N><W><Y><K><A><E><L><N><G><K><D><G><F><I><P><K><N><Y><I><E><M><K><P><H><P><W><F><F><G><K><I><P><R><A><K><A><E><E><M><L><S><K><Q><R><H><D><G><A><F><L><I><R><E><S><E><S><A><P><G><D><F><S><L><S><V><K><F><G><N><D><V><Q><H... | Does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.<BOP> | P62993 |
Q5QJE6 | TDIF2_HUMAN | Terminal deoxynucleotidyltransferase-interacting factor 2 | Homo | <M><V><V><T><R><S><A><R><A><K><A><S><I><Q><A><A><S><A><E><S><S><G><Q><K><S><F><A><A><N><G><I><Q><A><H><P><E><S><S><T><G><S><D><A><R><T><T><A><E><S><Q><T><T><G><K><Q><S><L><I><P><R><T><P><K><A><R><K><R><K><S><R><T><T><G><S><L><P><K><G><T><E><P><S><T><D><G><E><T><S><E><A><E><S><N><Y><S><V><S><E><H><H><D><T><I><L><R><V><T... | Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein.<BOP> | Q5QJE6 |
Q92536 | YLAT2_HUMAN | y(+)L-type amino acid transporter 2 | Homo | <M><E><A><R><E><P><G><R><P><T><P><T><Y><H><L><V><P><N><T><S><Q><S><Q><V><E><E><D><V><S><S><P><P><Q><R><S><S><E><T><M><Q><L><K><K><E><I><S><L><L><N><G><V><S><L><V><V><G><N><M><I><G><S><G><I><F><V><S><P><K><G><V><L><V><H><T><A><S><Y><G><M><S><L><I><V><W><A><I><G><G><L><F><S><V><V><G><A><L><C><Y><A><E><L><G><T><T><I><T><K... | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transpo... | Q92536 |
Q86Y29 | BAGE3_HUMAN | Cancer/testis antigen 2.3 | Homo | <M><A><A><G><V><V><F><L><A><L><S><A><Q><L><L><Q><A><R><L><M><K><E><E><S><P><V><V><S><W><R><L><E><P><E><D><G><T><A><L><D><V><H><F><V><S><T><L><E><P><L><S><N><A><V><K><R><N><V><P><R><C><I><I><I><L><V><L><Q><E><P><T><P><F><R><I><S><V><T><S><S><C><F><V><Q><N><T><L><T><K><L><L><K><D><R><R><K><M><Q><T><V><Q><C><A><T><A><Q><E... | Unknown. Candidate gene encoding tumor antigens.<BOP> | Q86Y29 |
P22001 | KCNA3_HUMAN | Voltage-gated potassium channel subunit Kv1.3 | Homo | <M><D><E><R><L><S><L><L><R><S><P><P><P><P><S><A><R><H><R><A><H><P><P><Q><R><P><A><S><S><G><G><A><H><T><L><V><N><H><G><Y><A><E><P><A><A><G><R><E><L><P><P><D><M><T><V><V><P><G><D><H><L><L><E><P><E><V><A><D><G><G><G><A><P><P><Q><G><G><C><G><G><G><G><C><D><R><Y><E><P><L><P><P><S><L><P><A><A><G><E><Q><D><C><C><G><E><R><V><V... | Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.<BO... | P22001 |
Q9H867 | MT21D_HUMAN | Valosin-containing protein lysine methyltransferase | Homo | <M><A><D><T><L><E><S><S><L><E><D><P><L><R><S><F><V><R><V><L><E><K><R><D><G><T><V><L><R><L><Q><Q><Y><S><S><G><G><V><G><C><V><V><W><D><A><A><I><V><L><S><K><Y><L><E><T><P><E><F><S><G><D><G><A><H><A><L><S><R><R><S><V><L><E><L><G><S><G><T><G><A><V><G><L><M><A><A><T><L><G><A><D><V><V><V><T><D><L><E><E><L><Q><D><L><L><K><M><N... | Protein N-lysine methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity.<BOP> | Q9H867 |
Q9UGJ0 | AAKG2_HUMAN | H91620p | Homo | <M><G><S><A><V><M><D><T><K><K><K><K><D><V><S><S><P><G><G><S><G><G><K><K><N><A><S><Q><K><R><R><S><L><R><V><H><I><P><D><L><S><S><F><A><M><P><L><L><D><G><D><L><E><G><S><G><K><H><S><S><R><K><V><D><S><P><F><G><P><G><S><P><S><K><G><F><F><S><R><G><P><Q><P><R><P><S><S><P><M><S><A><P><V><R><P><K><T><S><P><G><S><P><K><T><V><F><P... | AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carboh... | Q9UGJ0 |
Q5KU26 | COL12_HUMAN | Scavenger receptor with C-type lectin | Homo | <M><K><D><D><F><A><E><E><E><E><V><Q><S><F><G><Y><K><R><F><G><I><Q><E><G><T><Q><C><T><K><C><K><N><N><W><A><L><K><F><S><I><I><L><L><Y><I><L><C><A><L><L><T><I><T><V><A><I><L><G><Y><K><V><V><E><K><M><D><N><V><T><G><G><M><E><T><S><R><Q><T><Y><D><D><K><L><T><A><V><E><S><D><L><K><K><L><G><D><Q><T><G><K><K><A><I><S><T><N><S><E... | Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to... | Q5KU26 |
Q96A09 | TET5B_HUMAN | Non-canonical poly(A) polymerase FAM46B | Homo | <M><M><P><S><E><S><G><A><E><R><R><D><R><A><A><A><Q><V><G><T><A><A><A><T><A><V><A><T><A><A><P><A><G><G><G><P><D><P><E><A><L><S><A><F><P><G><R><H><L><S><G><L><S><W><P><Q><V><K><R><L><D><A><L><L><S><E><P><I><P><I><H><G><R><G><N><F><P><T><L><S><V><Q><P><R><Q><I><V><Q><V><V><R><S><T><L><E><E><Q><G><L><H><V><H><S><V><R><L><H... | Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group in an ATP hydrolysis-dependent manner . May be involved in maintaining the translation efficiency of at least some genes through preventing degradation of their mRNAs . Prefers RNA molecules that are aden... | Q96A09 |
Q8N6P7 | I22R1_HUMAN | ZcytoR11 | Homo | <M><R><T><L><L><T><I><L><T><V><G><S><L><A><A><H><A><P><E><D><P><S><D><L><L><Q><H><V><K><F><Q><S><S><N><F><E><N><I><L><T><W><D><S><G><P><E><G><T><P><D><T><V><Y><S><I><E><Y><K><T><Y><G><E><R><D><W><V><A><K><K><G><C><Q><R><I><T><R><K><S><C><N><L><T><V><E><T><G><N><L><T><E><L><Y><Y><A><R><V><T><A><V><S><A><G><G><R><S><A><T... | Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling t... | Q8N6P7 |
Q9P016 | THYN1_HUMAN | Thymocyte protein Thy28 | Homo | <M><S><R><P><R><K><R><L><A><G><T><S><G><S><D><K><G><L><S><G><K><R><T><K><T><E><N><S><G><E><A><L><A><K><V><E><D><S><N><P><Q><K><T><S><A><T><K><N><C><L><K><N><L><S><S><H><W><L><M><K><S><E><P><E><S><R><L><E><K><G><V><D><V><K><F><S><I><E><D><L><K><A><Q><P><K><Q><T><T><C><W><D><G><V><R><N><Y><Q><A><R><N><F><L><R><A><M><K><L... | Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.<BOP> | Q9P016 |
O15535 | ZSC9_HUMAN | Zinc finger protein 193 | Homo | <M><N><T><N><S><K><E><V><L><S><L><G><V><Q><V><P><E><A><W><E><E><L><L><T><M><K><V><E><A><K><S><H><L><Q><W><Q><E><S><R><L><K><R><S><N><P><L><A><R><E><I><F><R><R><H><F><R><Q><L><C><Y><Q><E><T><P><G><P><R><E><A><L><T><R><L><Q><E><L><C><Y><Q><W><L><R><P><H><V><S><T><K><E><Q><I><L><D><L><L><V><L><E><Q><F><L><S><I><L><P><K><E... | May be involved in transcriptional regulation.<BOP> | O15535 |
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