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Low-affinity nerve growth factor receptor has been shown to interact with:
* FSCN1,
* MAGEH1,
* NDN,
* NGFRAP1
* NGF,
* PRKACB,
* TRAF2, and
* TRAF4.
*Nogo-66 receptor
*c-Jun N-terminal kinases
* RhoA
* Rho GDP dissociation inhibitor (RhoGDI)
*NF-kB
*Neurotrophin-3
*Brain-derived neurotrophic factor
*Neurotrophi... | 1 | Biochemistry |
Given that DNA and RNA polymerases both carry out template-dependent nucleotide polymerization, it might be expected that the two types of enzymes would be structurally related. However, x-ray crystallographic studies of both types of enzymes reveal that, other than containing a critical Mg ion at the catalytic site, t... | 1 | Biochemistry |
Many inhibitors of glycosyltransferases are known. Some of these are natural products, such as moenomycin, an inhibitor of peptidoglycan glycosyltransferases, the nikkomycins, inhibitors of chitin synthase, and the echinocandins, inhibitors of fungal β-1,3-glucan synthases. Some glycosyltransferase inhibitors are of us... | 0 | Organic Chemistry |
Raman spectroscopy is one of the easiest methods to integrate into a heterogeneous operando experiment, as these reactions typically occur in the gas phase, so there is very low litter interference and good data can be obtained for the species on the catalytic surface. In order to use Raman, all that is required is to ... | 7 | Physical Chemistry |
The processes just above have assumed that the boundaries are also impermeable to particles. Otherwise, we may assume boundaries that are rigid, but are permeable to one or more types of particle. Similar considerations then hold for the chemical potential–particle number conjugate pair, which is concerned with the tra... | 7 | Physical Chemistry |
Monomers with aromatic motifs such as bis(merocyanine), oligo(para-phenylenevinylene) (OPV), perylene bisimide (PBI) dye, cyanine dye, corannulene and nano-graphene derivatives have been employed to prepare supramolecular polymers. In some cases, hydrogen bonding side chains appended onto the core aromatic motif help ... | 6 | Supramolecular Chemistry |
The Nernst–Planck equation is applied in describing the ion-exchange kinetics in soils. It has also been applied to membrane electrochemistry. | 7 | Physical Chemistry |
In chemical terms, creatinine is a lactam and an imidazolidinone, so a spontaneously formed cyclic derivative of creatine.
Several tautomers of creatinine exist; ordered by contribution, they are:
*2-Amino-1-methyl-1H-imidazol-4-ol (or 2-amino-1-methylimidazol-4-ol)
*2-Amino-1-methyl-4,5-dihydro-1H-imidazol-4-one
*2-Im... | 1 | Biochemistry |
He is also the co-author of three popular books on total synthesis:
#Classics in Total Synthesis I, 1996
#Classics in Total Synthesis II, 2003
#Classics in Total Synthesis III, 2011
Additionally, he authored or co-authored several other books:
#Molecules That Changed the World, 2008
#Handbook of Combinatorial Chemistr... | 0 | Organic Chemistry |
In 1954, the International Committee for Weights and Measures (CIPM) established the definition of the Kelvin as 1/273.16 of the absolute temperature of the triple point of water. Waters with different isotopic compositions had slightly different triple points. Thus, the International Committee for Weights and Measures... | 9 | Geochemistry |
Sulfide is incorporated into cysteine, catalyzed by O-acetylserine (thiol)lyase, with O-acetylserine as substrate. The synthesis of O-acetylserine is catalyzed by serine acetyltransferase and together with O-acetylserine (thiol)lyase it is associated as enzyme complex named cysteine synthase.
The formation of cysteine ... | 1 | Biochemistry |
A further method to synthesize Grignard reagents involves reaction of Mg with an organozinc compound. This method has been used to make adamantane-based Grignard reagents, which are, due to C-C coupling side reactions, difficult to make by the conventional method from the alkyl halide and Mg. The reductive transmetala... | 0 | Organic Chemistry |
Gold extraction is the extraction of gold from dilute ores using a combination of chemical processes. Gold mining produces about 3600 tons annually, and another 300 tons is produced from recycling.
Since the 20th century, gold has been principally extracted in a cyanide process by leaching the ore with cyanide solution... | 8 | Metallurgy |
Pesticide residue refers to the pesticides that may remain on or in food after they are applied to food crops. The maximum residue limits (MRL) of pesticides in food are carefully set by the regulatory authorities to ensure, to their best judgement, no health impacts. Regulations such as pre-harvest intervals also ofte... | 2 | Environmental Chemistry |
The properties of the polymer are influenced by the chain length. The correct chain length ensures that the encapsulant is not released over time. Avoiding the release of QDs and other toxic particles is critical to prevent unintentional cell necrosis in patients.
The length of the polymer is controlled by two factors:... | 7 | Physical Chemistry |
The Laplace-Perrin distribution law can be rearranged to give the sedimentation length . The sedimentation length describes the probability of finding a colloidal particle at a height above the point of reference . At the length above the reference point, the concentration of colloidal particles decreases by a factor... | 1 | Biochemistry |
The disulfide anion is , or S−S. In disulfide, sulfur exists in the reduced state with oxidation number −1. Its electron configuration then resembles that of a chlorine atom. It thus tends to form a covalent bond with another S center to form group, similar to elemental chlorine existing as the diatomic Cl. Oxygen ma... | 0 | Organic Chemistry |
Vancomycin is indicated for the treatment of serious, life-threatening infections by Gram-positive (aerobic and/or anaerobic) bacteria unresponsive to other antibiotics.
The increasing emergence of vancomycin-resistant enterococci has resulted in the development of guidelines for use by the Centers for Disease Control ... | 0 | Organic Chemistry |
Fahy was named as a Fellow of the Society for Cryobiology in 2014, and in 2010 he received the Distinguished Scientist Award for Reproductive Biology from the Reproductive Biology Professional Group of the American Society of Reproductive Medicine. He received the Cryopreservation Award from the International Longevit... | 1 | Biochemistry |
Some [NiFe]-containing proteins are known to sense H and thus regulate transcription.
Copper-containing proteins are known to sense ethylene, which is known to be a hormone relevant to the ripening of fruit. This example illustrates the essential role of organometallic chemistry in nature, as few molecules outside of ... | 0 | Organic Chemistry |
Drimane is a bicyclic sesquiterpene. It is the parent structure of many natural products with various biological activity.
Among the notable drimanes are:
*Polygodial, found in several different plants
*Multiple compounds found in several members of the family Canellaceae | 0 | Organic Chemistry |
S-Adenosylmethionine synthetase (), also known as methionine adenosyltransferase (MAT), is an enzyme that creates S-adenosylmethionine (also known as AdoMet, SAM or SAMe) by reacting methionine (a non-polar amino acid) and ATP (the basic currency of energy). | 1 | Biochemistry |
Cold water pitting of copper tube occurs in only a minority of installations. Copper water tubes are usually guaranteed by the manufacturer against manufacturing defects for a period of 50 years. The vast majority of copper systems far exceed this time period but a small minority may fail after a comparatively short t... | 8 | Metallurgy |
A promoter is defined in RegulonDB as the nucleotide sequence 60 bases upstream and 20 downstream from the precise initiation of transcription or +1. Terminators are regions where transcription ends, and RNA Polymerase unbinds from DNA. | 1 | Biochemistry |
Galactogen is a polysaccharide of galactose that functions as energy storage in pulmonate snails and some Caenogastropoda. This polysaccharide is exclusive of the reproduction and is only found in the albumen gland from the female snail reproductive system and in the perivitelline fluid of eggs. Furthermore, galactogen... | 0 | Organic Chemistry |
Microbiota-accessible carbohydrates (MACs) are carbohydrates that are resistant to digestion by a hosts metabolism, and are made available for gut microbes, as prebiotics, to ferment or metabolize into beneficial compounds, such as short chain fatty acids. The term, ‘‘microbiota-accessible carbohydrate’’ contributes to... | 0 | Organic Chemistry |
The subgroup structure suggests another way to compose an arbitrary isometry:
: Pick a fixed point, and a mirror through it.
# If the isometry is odd, use the mirror; otherwise do not.
# If necessary, rotate around the fixed point.
# If necessary, translate.
This works because translations are a normal subgroup of the ... | 3 | Analytical Chemistry |
In 1855, physiologist Adolf Fick first reported his now well-known laws governing the transport of mass through diffusive means. Ficks work was inspired by the earlier experiments of Thomas Graham, which fell short of proposing the fundamental laws for which Fick would become famous. Ficks law is analogous to the rela... | 7 | Physical Chemistry |
DNA methylation is the process in which a methyl group is added to either a cytosine or adenine. This process causes the activation or inactivation of gene expression, thereby resulting in gene regulation in eukaryotic cells. DNA methylation process is also known to be involved in certain types of cancer formation. In ... | 1 | Biochemistry |
It is disputed that Wöhlers synthesis sparked the downfall of the theory of vitalism, which states that organic matter possessed a certain vital force' common to all living things. Prior to the Wöhler synthesis, the work of John Dalton and Jöns Jacob Berzelius had already convinced chemists that organic and inorganic m... | 0 | Organic Chemistry |
STARR-seq is a technique similar to MPRAs to assay enhancer activity of randomly sheared genomic fragments. In the original publication, randomly sheared fragments of the Drosophila genome were placed downstream of a minimal promoter. Candidate enhancers amongst the randomly sheared fragments will transcribe themselves... | 1 | Biochemistry |
The Kroll process was invented in 1940 by William J. Kroll in Luxembourg. After moving to the United States, Kroll further developed the method for the production of zirconium.
Many methods had been applied to the production of titanium metal, beginning with a report in 1887 by Nilsen and Pettersen using sodium, whic... | 8 | Metallurgy |
To operate in this cycle, the desiccant is required to absorb moisture from air coming off of the coil that is colder and about 98% RH and to desorb moisture to air that is warmer and at a lower RH. The desiccant is regenerated by the vapor pressure differential inherent in the RH differences rather than heat or temper... | 7 | Physical Chemistry |
The use of two wires of iridium/rhodium alloys can provide a thermocouple that can be used up to about 2000 °C in inert atmospheres. | 8 | Metallurgy |
* In the Markó–Lam deoxygenation, an alcohol could be almost instantaneously deoxygenated by electroreducing its toluate ester.
* In concept, adiponitrile is prepared from dimerizing acrylonitrile:
:In practice,the cathodic hydrodimerization of activated olefins is applied industrially in the synthesis of adiponitrile ... | 7 | Physical Chemistry |
In case of a porous materials many issues have been raised both about the physical meaning of the calculated pore diameter and the real possibility to use this equation for the calculation of the contact angle of the solid, even if this method is often offered by much software as consolidated. Change of weight as a fun... | 7 | Physical Chemistry |
Thyroids secretory capacity (G, also referred to as thyroids incretory capacity, maximum thyroid hormone output, T4 output or, if calculated from serum levels of thyrotropin and thyroxine, as SPINA-GT) is the maximum stimulated amount of thyroxine that the thyroid can produce in a given time-unit (e.g. one second). | 1 | Biochemistry |
For an electrode in a solution with a particular size and geometry, the reversible charge injection limit is the amount of charge that can move from the electrode to the surroundings without causing a chemical reaction that is irreversible. | 7 | Physical Chemistry |
In mathematical statistics, the Kullback–Leibler (KL) divergence (also called relative entropy and I-divergence), denoted , is a type of statistical distance: a measure of how one probability distribution is different from a second, reference probability distribution . A simple interpretation of the KL divergence of ... | 7 | Physical Chemistry |
Bosons are quantum mechanical particles that follow Bose–Einstein statistics, or equivalently, that possess integer spin. These particles can be classified as elementary: these are the Higgs boson, the photon, the gluon, the W/Z and the hypothetical graviton; or composite like the atom of hydrogen, the atom of O, the n... | 7 | Physical Chemistry |
The integrated stress response can be triggered within a cell due to either extrinsic or intrinsic conditions. Extrinsic factors include hypoxia, amino acid deprivation, glucose deprivation, viral infection and presence of oxidants. The main intrinsic factor is endoplasmic reticulum stress due to the accumulation of un... | 1 | Biochemistry |
In the simplest case, the linear N–H molecule (imidogen) has its nitrogen atom sp hybridized, with two of its four non-bonded electrons as a lone pair in an sp orbital and the other two occupying a degenerate pair of p orbitals. The electron configuration is consistent with Hund's rule: the low energy form is a triplet... | 0 | Organic Chemistry |
Total inorganic carbon (C or TIC) is the sum of the inorganic carbon species.
Carbon compounds can be distinguished as either organic or inorganic, and dissolved or particulate, depending on their composition. Organic carbon forms the backbone of key components of organic compounds such as proteins, lipids, carbohydrat... | 9 | Geochemistry |
A plasmid is a double stranded circular DNA molecule commonly used for molecular cloning. Plasmids are generally 2 to 4 kilobase-pairs (kb) in length and are capable of carrying inserts up to 15kb. Plasmids contain an origin of replication allowing them to replicate inside a bacterium independently of the host chromoso... | 1 | Biochemistry |
Optical transfection is a biomedical technique that entails introducing nucleic acids (i.e. genetic material such as DNA) into cells using light. All cells are surrounded by a plasma membrane, which prevents many substances from entering or exiting the cell. Lasers can be used to burn a tiny hole in this membrane, allo... | 1 | Biochemistry |
The Gouy-Stodola theorem is often applied upon an open thermodynamic system, which can exchange heat with some thermal reservoirs. It holds both for systems which cannot exchange mass, and systems which mass can enter and leave.
Observe such a system, as sketched in the image shown, as it is going through some process.... | 7 | Physical Chemistry |
SedDB was developed to complement current geological data systems (PetDB, EarthChem, NavDat and Georoc) with an integrated and easily accessible compilation of geochemical data of marine and continental sediments to be utilized for sedimentological, geochemical, petrological, oceanographic, and paleoclimate research, a... | 9 | Geochemistry |
Medium-pressure mercury-vapor lamps have historically been the industry standard for curing products with ultraviolet light. The bulbs work by sending an electric discharge to excite a mixture of mercury and noble gases, generating a plasma. Once the mercury reaches a plasma state, it irradiates a high spectral output ... | 5 | Photochemistry |
Take the simplest CHX–CH system as an example; the donor orbital is σ(C–H) orbital and the acceptor is σ*(C–X). When moving from fluorine to chlorine, then to bromine, the electronegativity of the halogen and the energy level of the σ*(C–X) orbitals decreases. Consequently, the general trend of acceptors can be summari... | 4 | Stereochemistry |
In contrast with crystals, liquids have no long-range order (in particular, there is no regular lattice), so the structure factor does not exhibit sharp peaks. They do however show a certain degree of short-range order, depending on their density and on the strength of the interaction between particles. Liquids are iso... | 3 | Analytical Chemistry |
Artificial photosynthesis is a chemical process that biomimics the natural process of photosynthesis. The term artificial photosynthesis is used loosely, refer to any scheme for capturing and storing energy from sunlight by producing a fuel, specifically a solar fuel. An advantage of artificial photosynthesis is that t... | 5 | Photochemistry |
Epimerization is a chemical process where an epimer is converted to its diastereomeric counterpart. It can happen in condensed tannins depolymerization reactions. Epimerization can be spontaneous (generally a slow process), or catalysed by enzymes, e.g. the epimerization between the sugars N-acetylglucosamine and N-ace... | 4 | Stereochemistry |
Other bodies may define classes of reference material differently. WHO guidelines for biological reference materials provide the terms:
* Reference standards: materials that are used as calibrators in assays
* International biological measurement standard: a biological substance provided to enable the results of biol... | 3 | Analytical Chemistry |
In response to a systemic bacterial infection, the immune system initiates a process known as "iron withholding". If bacteria are to survive, then they must obtain iron from their environment. Disease-causing bacteria do this in many ways, including releasing iron-binding molecules called siderophores and then reabsorb... | 1 | Biochemistry |
Pipecolic acid (piperidine-2-carboxylic acid) is an organic compound with the formula HNCHCOH. It is a carboxylic acid derivative of piperidine and, as such, an amino acid, although not one encoded genetically. Like many other α-amino acids, pipecolic acid is chiral, although the S-stereoisomer is more common. It is a ... | 1 | Biochemistry |
Many cross-couplings entail forming carbon–carbon bonds.
The restrictions on carbon atom geometry mainly inhibit β-hydride elimination when complexed to the catalyst. | 0 | Organic Chemistry |
Zintl phases that contain molecule-like polyanions will often separate into its constituent anions and cations in liquid ammonia, ethylenediamene, crown ethers, or cryptand solutions. Therefore, they are referred to as Zintl ions. The term clusters is also used to emphasize them as groups with homonuclear bonding. The... | 7 | Physical Chemistry |
Currently, the two most prominent areas of co-receptor research are investigations regarding HIV and cancer. HIV research is highly focused on the adaption of HIV strains to a variety of host co-receptors. Cancer research is mostly focused on enhancing the immune response to tumor cells, while some research also involv... | 1 | Biochemistry |
CoQ is metabolized in all tissues, with the metabolites being phosphorylated in cells. CoQ10 is reduced to ubiquinol during or after absorption in the small intestine. It is absorbed by chylomicrons, and redistributed in the blood within lipoproteins. Its elimination occurs via biliary and fecal excretion. | 1 | Biochemistry |
In fuel cells, electro-osmosis causes protons moving through a proton exchange membrane (PEM) to drag water molecules from one side (anode) to the other (cathode). | 7 | Physical Chemistry |
Activation, in chemistry and biology, is the process whereby something is prepared or excited for a subsequent reaction. | 7 | Physical Chemistry |
Another possible biosignature might be morphology since the shape and size of certain objects may potentially indicate the presence of past or present life. For example, microscopic magnetite crystals in the Martian meteorite ALH84001 are one of the longest-debated of several potential biosignatures in that specimen. T... | 2 | Environmental Chemistry |
Photocyclization can be carried out with ortho-, meta-, and para-substituted stilbene substrates.
ortho-Substituted substrates generally give 1-substituted phenanthrenes, unless the substituent
is a good leaving group, in which case elimination to form unsubstituted phenanthrene occurs. meta-
Substituted substrates giv... | 5 | Photochemistry |
The high surface tension of water causes droplets to assume a nearly spherical shape, since a sphere has minimal surface area, and this shape therefore minimizes the solid-liquid surface energy. On contact of liquid with a surface, adhesion forces result in wetting of the surface. Either complete or incomplete wetting ... | 7 | Physical Chemistry |
Thermal expansion is the tendency of matter to change its shape, area, volume, and density in response to a change in temperature, usually not including phase transitions.
Temperature is a monotonic function of the average molecular kinetic energy of a substance. When a substance is heated, molecules begin to vibrate a... | 7 | Physical Chemistry |
Translation is one of the key energy consumers in cells, hence it is strictly regulated. Numerous mechanisms have evolved that control and regulate translation in eukaryotes as well as prokaryotes. Regulation of translation can impact the global rate of protein synthesis which is closely coupled to the metabolic and p... | 1 | Biochemistry |
In many photo-productive systems this charge separation is kinetically isolated by delivery of the electron to a lower energy conductor attached to the p/n junction or into an electron transport chain. In this case some of the energy can be captured to do work. If the electron is not kinetically isolated thermodynamics... | 5 | Photochemistry |
The residence time of a fluid parcel is the total time that the parcel has spent inside a control volume (e.g.: a chemical reactor, a lake, a human body). The residence time of a set of parcels is quantified in terms of the frequency distribution of the residence time in the set, which is known as residence time distri... | 9 | Geochemistry |
The trifluoromethyl group is a functional group that has the formula -CF. The naming of is group is derived from the methyl group (which has the formula -CH), by replacing each hydrogen atom by a fluorine atom. Some common examples are trifluoromethane H–, 1,1,1-trifluoroethane –, and hexafluoroacetone –CO–. Compounds ... | 0 | Organic Chemistry |
Topochemical polymerization is a polymerization method performed by monomers aligned in the crystal state. In this process, the monomers are crystallised and polymerised under external stimuli such as heat, light, or pressure. Compared to traditional polymerisation, the movement of monomers was confined by the crystal ... | 7 | Physical Chemistry |
Since the carbon cycle is tightly connected to the issue of ocean acidification, the most effective method for minimizing the effects of ocean acidification is to slow climate change. Anthropogenic inputs of CO can be reduced through methods such as limiting the use of fossil fuels and employing renewable energies. Thi... | 9 | Geochemistry |
Mitochondrial threshold effect is a phenomenon where the number of mutated mtDNA has surpassed a certain threshold which causes the electron transport chain and ATP synthesis of a mitochondrion to fail. There isn't a set number that needs to be surpassed, however, it is associated with an increase of the number of muta... | 1 | Biochemistry |
In 1987 Parker was a fellow of the John Simon Guggenheim Foundation. In 2009 the Parker was elected a fellow of the American Chemical Society and she received the Francis P. Garvan-John M. Olin Medal from the American Chemical Society. In 2017 she received the Arthur C. Cope Scholar Award in recognition of her work syn... | 0 | Organic Chemistry |
Intravesical drug administration is the delivery of pharmaceuticals to the urinary bladder through a catheter. This route of administration is used for the therapy of bladder cancer and interstitial cystitis. The retention of dosage forms in the bladder is relatively poor, which is related to the need for a periodical ... | 1 | Biochemistry |
dPCR measures the actual number of molecules (target DNA) as each molecule is in one droplet, thus making it a discrete “digital” measurement. It provides absolute quantification because dPCR measures the positive fraction of samples, which is the number of droplets that are fluorescing due to proper amplification. Thi... | 1 | Biochemistry |
Many of the competitive single-molecule sequencing methods rely on the incorporation of fluorescently labeled nucleotides. In next-generation sequencing, the fluorescence signal of clusters can be easily detected. However, when the same concept is applied to single-molecule sequencing, the largest complication result... | 1 | Biochemistry |
Maximum entropy spectral estimation is a method of spectral density estimation. The goal is to improve the spectral quality based on the principle of maximum entropy. The method is based on choosing the spectrum which corresponds to the most random or the most unpredictable time series whose autocorrelation function ag... | 7 | Physical Chemistry |
Surface integrity is the surface condition of a workpiece after being modified by a manufacturing process. The term was coined by Michael Field and John F. Kahles in 1964.
The surface integrity of a workpiece or item changes the material's properties. The consequences of changes to surface integrity are a mechanical en... | 8 | Metallurgy |
Force spectroscopy is a method to measure forces between the tip and the sample. In this method the topographic feedback loop is disabled, and the tip is ramped towards the surface, then back. During the ramp the amplitude or frequency shift (depending on the mode of operation) is recorded to show the strength of the i... | 6 | Supramolecular Chemistry |
When a concrete structure is heavily reinforced, the very dense rebar network can block the contraction movement of the protecting concrete cover located above the external layer of reinforcement bars due to the natural drying shrinkage process. As a consequence, a network of fissures with the characteristic honeycomb ... | 8 | Metallurgy |
1,1-Dichloro-1-fluoroethane is mainly used as a solvent and foam blowing agent under the names R-141b and HCFC-141b. It is a class 2 ozone depleting substance undergoing a global phaseout from production and use under the Montreal Protocol since the late 1990s. It is being replaced by HFCs within some applications. | 2 | Environmental Chemistry |
The method numbers generally range from 1 to 9000 and may have modification letters appended to the end, signifying a newer version of the method has been released. Some ranges of numbers appear to be organized with intention, for example methods 1-99 being air methods or the 7000s being for hazardous waste. Others num... | 3 | Analytical Chemistry |
Imprelis is a selective herbicide created by DuPont. The active ingredient is aminocyclopyrachlor, a synthetic auxin. | 2 | Environmental Chemistry |
MgCu is a binary intermetallic compound of magnesium (Mg) and copper (Cu) adopting cubic crystal structure, more specifically the C15 Laves phase. The space group of MgCu is Fdm with lattice parameter a = 7.04 Å. | 8 | Metallurgy |
Fulmer Research Institute was founded in 1945 as a UK contract research and development organization specializing in materials technology and related areas of physics and chemistry. It was modelled on American contract research companies such as Battelle Memorial Institute and The Mellon Institute of Industrial Resear... | 8 | Metallurgy |
The starting reactants for these reactions are hydrogen cyanide (HCN) as well as HCN derivatives and acetylene. Both of these are hypothesized to be present on the early Earth. The conditions this reaction occurs in are a relatively moderate temperature of 35 degrees C and in anoxic or oxygen free conditions. The early... | 9 | Geochemistry |
Targeting of TNRF2 in tumor cells is associated with increased tumor cell death and decreased progression of tumor cell growth.
Increased expression of TNFR2 is found in breast cancer, cervical cancer, colon cancer, and renal cancer. A link between the expression of TNRF2 in tumor cells and late-stage cancer has been d... | 1 | Biochemistry |
Individual progeny genomes are excised from genomic replicative concatemers starting by introducing breaks in replication origins, usually by the replication initiator protein. This results in the establishment of new replication forks that replicate the telomeres in a combination of terminal resolution and junction re... | 1 | Biochemistry |
The suffix -yl is used in organic chemistry to form names of radicals, either separate species (called free radicals) or chemically bonded parts of molecules (called moieties). It can be traced back to the old name of methanol, "methylene" (from , wine and , wood, forest), which became shortened to "methyl" in compou... | 0 | Organic Chemistry |
There are numerous cell signalling pathways that exhibit cross-talk with the PI3K pathway, potentially allowing cancer cells to escape inhibition of PI3K. As such, inhibition of the PI3K pathway alongside other targets could offer a synergistic response, such as that seen with PI3K and MEK co-targeted inhibition in lun... | 1 | Biochemistry |
The TLK model is credited as having originated from papers published in the 1920s by the German chemist W. Kossel and the Bulgarian chemist I. N. Stranski wherein the thermodynamic stability of step edges were discussed. | 7 | Physical Chemistry |
For a solid crystalline ionic compound the enthalpy change in forming the solid from gaseous ions is termed the lattice energy. The experimental value for the lattice energy can be determined using the Born–Haber cycle. It can also be calculated (predicted) using the Born–Landé equation as the sum of the electrostatic... | 6 | Supramolecular Chemistry |
* ASBMB Award for Exemplary Contributions to Education
* ASBMB Leadership Awards
* ASBMB–Merck Award
* ASBMB Young Investigator Award
* Avanti Award in Lipids
* Bert and Natalie Vallee Award in Biomedical Science
* DeLano Award for Computational Biosciences
* Earl and Thressa Stadtman Distinguished Scientist Award
* Ea... | 1 | Biochemistry |
A variety of substituted derivatives of phen have been examined as ligands. Substituents at the 2,9 positions confer protection for the attached metal, inhibiting the binding of multiple equivalents of the phenanthroline. Such bulky ligands also favor trigonal or tetrahedral coordination at the metal. Phen itself for... | 3 | Analytical Chemistry |
The Boyle temperature is formally defined as the temperature for which the second virial coefficient, , becomes zero.
It is at this temperature that the attractive forces and the repulsive forces acting on the gas particles balance out
This is the virial equation of state and describes a real gas.
Since higher order v... | 7 | Physical Chemistry |
It is expected that [CO] will reach 500–1000 ppm by 2100. 96% of the past 400,000 years experienced below 280 ppm CO. From this figure, it is highly probable that genotypes of today’s plants have diverged from their pre-industrial relatives.
The gene HIC (high carbon dioxide) encodes a negative regulator for the develo... | 5 | Photochemistry |
A fluorogen is a ligand (fluorogenic ligand) which is not itself fluorescent, but when it is bound by a specific protein or RNA structure becomes fluorescent.
For instance, FAST is a variant of photoactive yellow protein which was engineered to bind chemical mimics of the GFP tripeptide chromophore.
Likewise, the spina... | 1 | Biochemistry |
Example phases are:
*β-MgAl: 1168 atoms per unit cell, face-centred cubic, atoms arranged in Friauf polyhedra.
*ξ'–AlPdMn: 318 atoms per unit cell, face-centred orthorhombic, atoms arranged in Mackay-type clusters.
* (Bergman phase): 163 atoms per unit cell, body centred cubic, atoms arranged in Bergman clusters.
* (... | 8 | Metallurgy |
The naturally occurring calcium cycle has been altered by human intervention. Calcium is predominantly extracted from limestone deposits to be utilised by many industrial processes. Purification of iron ore and aluminium, replacing asbestos brake linings and some coatings for electric cables, are some of these major us... | 1 | Biochemistry |
Quinaldine red (pronounced , abbreviated QR) is a dark green–red or black solid that does not dissolve easily in water (it is partly miscible). In addition to being used as colored indicator, quinaldine red is also used as a fluorescence probe and an agent in bleaching. | 3 | Analytical Chemistry |
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