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Concatenation of the tags, as developed in 2004, is different from that seen in SAGE. The cleavage of the tags with Xho1 and mixture of the different samples, followed by ligation, form the first concatenation step. The second step uses one of the restriction endonucleases with consensus to the adapter molecule attache... | 1 | Biochemistry |
Fibrin monomers are monomers of fibrin which are formed by the cleavage of fibrinogen by thrombin. Levels of fibrin monomers can be measured using blood tests and can serve as a marker of in vivo fibrinogenesis and coagulation activation. They may be useful in the evaluation hypercoagulability.
Levels of fibrin monomer... | 1 | Biochemistry |
RNA polymerase III can terminate transcription efficiently without the involvement of additional factors. The Pol III termination signal consists of a stretch of thymines (on the nontemplate strand) located within 40bp downstream from the 3' end of mature RNAs. The poly-T termination signal pauses Pol III | 1 | Biochemistry |
The word effusion derives from the Latin word, effundo, which means "shed, pour forth, pour out, utter, lavish, waste." | 7 | Physical Chemistry |
Demethylating agents are chemical substances that can inhibit methylation, resulting in the expression of the previously hypermethylated silenced genes (see Methylation#Cancer for more detail). Cytidine analogs such as 5-azacytidine (azacitidine) and 5-azadeoxycytidine (decitabine) are the most commonly used demethylat... | 1 | Biochemistry |
Convergent beam electron diffraction (CBED) is an electron diffraction technique where a convergent or divergent beam (conical electron beam) of electrons is used to study materials. | 3 | Analytical Chemistry |
Isoschizomers are pairs of restriction enzymes specific to the same recognition sequence. For example, SphI (CGTAC/G) and BbuI (CGTAC/G) are isoschizomers of each other. The first enzyme discovered which recognizes a given sequence is known as the prototype; all subsequently identified enzymes that recognize that seque... | 1 | Biochemistry |
Phenol red, sometimes labelled with a different name, such as "Guardex Solution #2", is used as a pH indicator in home swimming pool test kits.
Chlorine can result in the bleaching of the dye in the absence of thiosulfate to inhibit the oxidizing chlorine. High levels of bromine can convert phenol red to bromophenol re... | 3 | Analytical Chemistry |
CKLF like MARVEL transmembrane domain-containing 7 (i.e. CMTM7), previously termed chemokine-like factor superfamily 7 (i.e. CKLFSF7), is a protein that in humans is encoded by the CMTM7 gene. This gene, which is located in band 22 on the short (i.e. "p") arm of chromosome 3, and the protein that it encodes belong to t... | 1 | Biochemistry |
Significant are also the extensions of the polaron concept: acoustic polaron, piezoelectric polaron, electronic polaron, bound polaron, trapped polaron, spin polaron, molecular polaron, solvated polarons, polaronic exciton, Jahn-Teller polaron, small polaron, bipolarons and many-polaron systems. These extensions of the... | 7 | Physical Chemistry |
A contig (from contiguous) is a set of overlapping DNA segments that together represent a consensus region of DNA.
In bottom-up sequencing projects, a contig refers to overlapping sequence data (reads); in top-down sequencing projects, contig refers to the overlapping clones that form a physical map of the genome that ... | 1 | Biochemistry |
Eutrophication can have the following ecological effects: increased biomass of phytoplankton, changes in macrophyte species composition and biomass, dissolved oxygen depletion, increased incidences of fish kills, loss of desirable fish species. | 2 | Environmental Chemistry |
In other instances, molecular interactions between gas molecules previously adsorbed on a solid surface form significant interactions with gas molecules in the gaseous phases. Hence, adsorption of gas molecules to the surface is more likely to occur around gas molecules that are already present on the solid surface, re... | 7 | Physical Chemistry |
Particles can deposit in the nose, mouth, pharynx and larynx (the head airways region), deeper within the respiratory tract (from the trachea to the terminal bronchioles), or in the alveolar region. The location of deposition of aerosol particles within the respiratory system strongly determines the health effects of e... | 7 | Physical Chemistry |
A perfectly immobile fluorescent moiety when exited with polarized light will emit light which is also polarized. However, if a molecule is moving, it will tend to "scramble" the polarization of the light by radiating at a different direction from the incident light. | 1 | Biochemistry |
While the Kastle–Meyer test has been reported as being able to detect blood dilutions down to 1:10, there are a number of important limitations to the test. Chemical oxidants such as copper and nickel salts will cause the Kastle–Meyer reagent to turn pink before the addition of the hydrogen peroxide, thus it is vitally... | 3 | Analytical Chemistry |
Photolithographic methods are useful in patterning SAMs. SAMs are also useful in depositing nanostructures, because each adsorbate molecule can be tailored to attract two different materials. Current techniques utilize the head to attract to a surface, like a plate of gold. The terminal group is then modified to attra... | 6 | Supramolecular Chemistry |
GenePattern is a freely available computational biology open-source software package originally created and developed at the Broad Institute for the analysis of genomic data. Designed to enable researchers to develop, capture, and reproduce genomic analysis methodologies, GenePattern was first released in 2004. GenePat... | 1 | Biochemistry |
Resonance Raman spectroscopy explains the huge enhancement of Raman scattering intensity. Intermolecular and intramolecular charge transfers significantly enhance Raman spectrum peaks. In particular, the enhancement is huge for species adsorbing the metal surface due to the high-intensity charge transfers from the meta... | 7 | Physical Chemistry |
Some industrial-level sprays (with teflon or leather needle packing, variable speed agitator in pressure pot, separate air and fluid pressure regulators) can also be used for Dimetcote. | 8 | Metallurgy |
Self-healing hydrogels are a specialized type of polymer hydrogel. A hydrogel is a macromolecular polymer gel constructed of a network of crosslinked polymer chains. Hydrogels are synthesized from hydrophilic monomers by either chain or step growth, along with a functional crosslinker to promote network formation. A ne... | 7 | Physical Chemistry |
El-Shall was born in Cairo, Egypt, and spent his early life in Cairo. He is the grandson of Sheikh Mahmud Shaltut. He earned his B.S. degree in chemistry in 1976, and M.S. degree in physical chemistry in 1980 both from Cairo University. El-Shall earned his doctoral degree in physical chemistry from Georgetown Universit... | 7 | Physical Chemistry |
pVIII is the main coat protein of Ff phages. Peptides are usually fused to the N-terminus of pVIII. Usually peptides that can be fused to pVIII are 6-8 amino acids long. The size restriction seems to have less to do with structural impediment caused by the added section and more to do with the size exclusion caused by ... | 1 | Biochemistry |
Tollens' reagent is also used to apply a silver mirror to glassware; for example the inside of an insulated vacuum flask. The underlying chemical process is called silver mirror reaction. The reducing agent is glucose (an aldehyde) for such applications. Clean glassware is required for a high quality mirror. To incr... | 3 | Analytical Chemistry |
A 2011 study reported the detection of prions in urine from naturally and orally infected sheep with clinical scrapie agent and orally infected preclinical and infected white-tailed deer with clinical chronic wasting disease (CWD). This is the first report on prion detection of PrP from the urine of naturally or precli... | 1 | Biochemistry |
For black body emitters where photon recirculation is achieved via filters, Planck's law states that a black body emits light with a spectrum given by:
where I′ is the light flux of a specific wavelength, λ, given in units of 1 m⋅s. h is the Planck constant, k is the Boltzmann constant, c is the speed of light, and T i... | 7 | Physical Chemistry |
Breaking C–F bonds is of interest as a way to decompose and destroy organofluorine "forever chemicals" such as PFOA and perfluorinated compounds (PFCs). Candidate methods include catalysts, such as platinum atoms; photocatalysts; UV, iodide, and sulfite, radicals; etc. | 0 | Organic Chemistry |
The ability of pioneer factors to respond to extracellular signals to differentiate cell type has been studied as a potential component of hormone-dependent cancers. Hormones such as estrogen and IGFI are shown to increase pioneer factor concentration leading to a change in transcription. Known pioneer factors such a... | 1 | Biochemistry |
Public Analyst Laboratories in Cork, Dublin and Galway provide an analytical service to the Food Safety Authority. | 2 | Environmental Chemistry |
PKA phosphorylates proteins that have the motif Arginine-Arginine-X-Serine exposed, in turn (de)activating the proteins. Many possible substrates of PKA exist; a list of such substrates is available and maintained by the NIH.
As protein expression varies from cell type to cell type, the proteins that are available for ... | 1 | Biochemistry |
The light harvesting materials employed in biological photovoltaic devices can be categorised by their complexity; more complex materials are typically less efficient but more robust. | 7 | Physical Chemistry |
Conjugated systems form the basis of chromophores, which are light-absorbing parts of a molecule that can cause a compound to be colored. Such chromophores are often present in various organic compounds and sometimes present in polymers that are colored or glow in the dark. Chromophores often consist of a series of con... | 7 | Physical Chemistry |
Free hydride anions exist only under extreme conditions and are not invoked for homogeneous solution. Instead, many compounds have hydrogen centres with hydridic character.
Aside from electride, the hydride ion is the simplest possible anion, consisting of two electrons and a proton. Hydrogen has a relatively low elec... | 0 | Organic Chemistry |
Because of limited computing power, specialized simulation models have been developed for various purposes depending on the time scale:
a) Electronic scale simulations (density function theory, ab-initio molecular dynamics): sub-atomic length scale in femto-second time scale
b) Atomic scale simulations (MD): nano to mi... | 7 | Physical Chemistry |
Chromosome jumping enables two ends of a DNA sequence to be cloned without the middle section. Genomic DNA may be partially digested using restriction endonuclease and with the aid of DNA ligase, the fragments are circularized at low concentration. From a known sequence, a primer is designed to sequence across the circ... | 1 | Biochemistry |
* As a mordant when performing a Gram stain. It is applied for 1 minute after staining with crystal violet, but before ethanol to ensure that gram positive organisms' peptidoglycan remains stained, easily identifying it as a gram positive in microscopy.
* This solution is used as an indicator test for the presence of s... | 3 | Analytical Chemistry |
The glyoxylate cycle, a variation of the tricarboxylic acid cycle, is an anabolic pathway occurring in plants, bacteria, protists, and fungi. The glyoxylate cycle centers on the conversion of acetyl-CoA to succinate for the synthesis of carbohydrates. In microorganisms, the glyoxylate cycle allows cells to use two carb... | 1 | Biochemistry |
Once the presence of a carbonyl group has been identified using 2,4-dinitrophenylhydrazine (also known as Bradys reagent or 2,4-DNPH or 2,4-DNP), Tollens reagent can be used to distinguish ketone vs aldehyde. Tollens' reagent gives a negative test for most ketones, with alpha-hydroxy ketones being one exception.
The te... | 3 | Analytical Chemistry |
Negative thermal expansion is usually observed in non-close-packed systems with directional interactions (e.g. ice, graphene, etc.) and complex compounds (e.g. , , beta-quartz, some zeolites, etc.). However, in a paper, it was shown that negative thermal expansion (NTE) is also realized in single-component close-packed... | 7 | Physical Chemistry |
In the field of clinical imaging, with sufficient exposure, solarization of certain screen-film systems can occur which obscures details within the X-ray image and degrades the accuracy of the diagnosis. Even though degradation can occur this was found to be a rare phenomenon. | 7 | Physical Chemistry |
The technique is applied to conversions that proceed via unimolecular pathways. 2-Acetoxydioxane, when heated at 425 °C converts to the highly reactive dioxene, via loss of acetic acid.
2-Furonitrile has been prepared by flash-dehydration of 2-furoic acid amide or oxime over molecular sieves. The strained ring benzo... | 0 | Organic Chemistry |
The measurement volume is a convolution of illumination (excitation) and detection geometries, which result from the optical elements involved. The resulting volume is described mathematically by the point spread function (or PSF), it is essentially the image of a point source. The PSF is often described as an ellipsoi... | 7 | Physical Chemistry |
Sepro designs and builds modular and mobile processing plants for a wide range of mineral applications. Complete plants can be assembled using Sepro manufactured equipment along with equipment from third-party vendors and sub-contractors.
Sepro Mobile Plants are designed to be easily re-locatable as they are mounted o... | 8 | Metallurgy |
Mutations that affect the functioning of the integrated stress response may have debilitating effects on cells. For example, cells lacking the ATF4 gene are unable to elicit proper gene expression in response to stressors. This results in cells exhibiting issues with amino acid transport, glutathione biosynthesis and o... | 1 | Biochemistry |
Hollywood is a RNA splicing database containing data for the splicing of orthologous genes in different species. | 1 | Biochemistry |
Corrin is a heterocyclic compound. Although not known to exist on its own, the molecule is of interest as the parent macrocycle related to the cofactor and chromophore in vitamin B. Its name reflects that it is the "core" of vitamin B (cobalamins). Compounds with a corrin core are known as "corrins".
There are two chi... | 1 | Biochemistry |
Isodesmosine is a lysine derivative found in elastin. Isodesmosine is an isomeric pyridinium-based amino acid resulting from the condensation of four lysine residues between elastin proteins by lysyl-oxidase. These represent ideal biomarkers for monitoring elastin turnover because these special cross-links are only fou... | 1 | Biochemistry |
Isolation of the FeMo cofactor from nitrogenase is done through centrifugal sedimentation of nitrogenase into the MoFe protein and the Fe protein. The FeMo cofactor is extracted by treating the MoFe protein with acids. The first extraction is done with N,N-dimethylformamide and the second by a mixture of N-methylformam... | 7 | Physical Chemistry |
The G-less cassette technique is used to determine promoter strength beyond basal levels of transcription (i.e. in the presence of transcription activators or transcription factors). For example, to measure the effects of a TATA box consensus sequence modification in Saccharomyces cerevisiae in the presence of TFIID, G... | 1 | Biochemistry |
Negative-sense (3′-to-5′) viral RNA is complementary to the viral mRNA, thus a positive-sense RNA must be produced by an RNA-dependent RNA polymerase from it prior to translation. Like DNA, negative-sense RNA has a nucleotide sequence complementary to the mRNA that it encodes; also like DNA, this RNA cannot be translat... | 1 | Biochemistry |
Masking is the process of applying the maskant material to the surface to ensure that only desired areas are etched. Liquid maskants may be applied via dip-masking, in which the part is dipped into an open tank of maskant and then the maskant dried. Maskant may also be applied by flow coating: liquid maskant is flowed ... | 8 | Metallurgy |
The Journal of Photochemistry and Photobiology C: Photochemistry Reviews is abstracted and indexed in BIOSIS Previews, Chemistry & Chemical Engineering, Chemistry Citation Index, Current Contents/Physical, Chemical & Earth Sciences, Science Citation Index and Scopus. According to the Journal Citation Reports, the journ... | 5 | Photochemistry |
Instrumentation of supercritical fluid chromatography SFC has a similar setup to an HPLC instrument. The stationary phases are similar, and are packed inside similar column types. However, there are special features in these systems, because of the need to keep the mobile phase at supercritical fluidic state over the e... | 3 | Analytical Chemistry |
A provitamin is a substance that may be converted within the body to a vitamin. The term previtamin is a synonym.
The term "provitamin" is used when it is desirable to label a substance with little or no vitamin activity, but which can be converted to an active form by normal metabolic processes. | 1 | Biochemistry |
In addition to diagnosis and classification, EPIC-seq holds promise in predicting patient response to various cancer therapies, including immune-checkpoint inhibition (ICI). By analyzing changes in gene expression patterns captured through EPIC-seq, researchers can forecast patient response to PD-(L)1 blockade therapy,... | 1 | Biochemistry |
In organic synthesis, vinyl oxocarbenium ions (structure on right) can be utilized in a wide range of cycloaddition reactions. They are commonly employed as dienophiles in the Diels–Alder reaction. An electron withdrawing ketone is often added to the dienophile to increase the rate of the reaction, and these ketones ar... | 0 | Organic Chemistry |
The absorption of flutamide is complete upon oral ingestion. Food has no effect on the bioavailability of flutamide. Steady-state levels of hydroxyflutamide, the active form of flutamide, are achieved after 2 to 4 days administration. Levels of hydroxyflutamide are approximately 50-fold higher than those of flutamide a... | 4 | Stereochemistry |
In analytical chemistry, ashing or ash content determination is the process of mineralization by complete combustion for preconcentration of trace substances prior to a chemical analysis, such as chromatography, or optical analysis, such as spectroscopy. | 3 | Analytical Chemistry |
The term "pyrometer" was coined in the 1730s by Pieter van Musschenbroek, better known as the inventor of the Leyden jar. His device, of which no surviving specimens are known, may be now called a dilatometer because it measured the dilation of a metal rod.
The earliest example of a pyrometer thought to be in existence... | 8 | Metallurgy |
High-valent iron commonly denotes compounds and intermediates in which iron is found in a formal oxidation state > 3 that show a number of bonds > 6 with a coordination number ≤ 6. The term is rather uncommon for hepta-coordinate compounds of iron. It has to be distinguished from the terms hypervalent and hypercoordina... | 7 | Physical Chemistry |
The ortho effect occurs in Diels-Alder reactions when the Z-substituted dienophiles react with 1-substituted butadienes to give 3,4-disubstituted cyclohexenes, independent of the nature of diene substituents. | 4 | Stereochemistry |
The size of the substituents interacting at the 1 and 3 positions of an allylic group is often the largest factor contributing to the magnitude of the strain. As a rule, larger substituents will create a larger magnitude of strain. Proximity of bulky groups causes an increase in repulsive Van der Waals forces. This q... | 4 | Stereochemistry |
British Organic Geochemical Society (BOGS) is an organization that aims to promote, exchange and discuss all aspects of organic geochemistry. It also aims to facilitate academic and social networking between British organic geochemists. | 9 | Geochemistry |
Featuring divalent carbon, vinylidenes are unusual species in organic chemistry. They are unstable as solids or liquids but can be generated as stable dilute gases. The parent member of this series is methylidenecarbene. With the formula :C=CH), it is a carbene. | 0 | Organic Chemistry |
The Achmatowicz reaction, also known as the Achmatowicz rearrangement, is an organic synthesis in which a furan is converted to a dihydropyran. In the original publication by the Polish Chemist Osman Achmatowicz Jr. (b. 20 December 1931 in Vilnius) in 1971 furfuryl alcohol is reacted with bromine in methanol to 2,5-d... | 0 | Organic Chemistry |
Photodissociation is used to detect electromagnetic activity of ions, compounds, and clusters when spectroscopy cannot be directly applied. Low concentrations of analyte can be one inhibiting factor to spectroscopy esp. in the gas phase. Mass spectrometers, time-of-flight and ion cyclotron resonance have been used to s... | 7 | Physical Chemistry |
The BASIC assembly strategy was developed in 2015 and sought to address the limitations of previous assembly techniques, incorporating six key concepts from them: standard reusable parts; single-tier format (all parts are in the same format and are assembled using the same process); idempotent cloning; parallel (multip... | 1 | Biochemistry |
Plants have mechanisms that protect against adverse effects of strong light. The most studied biochemical protective mechanism is non-photochemical quenching of excitation energy. Visible-light-induced photoinhibition is ~25% faster in an Arabidopsis thaliana mutant lacking non-photochemical quenching than in the wild ... | 5 | Photochemistry |
FDA launched HIVE Open Source as a platform to support end to end needs for NGS analytics.
https://github.com/FDA/fda-hive
HIVE biocompute harmonization platform is at the core of High-throughput Sequencing Computational Standards for Regulatory Sciences (HTS-CSRS) project. Its mission is to provide the scientific com... | 1 | Biochemistry |
The depolarized voltage opens additional voltage-dependent potassium channels, and some of these do not close right away when the membrane returns to its normal resting voltage. In addition, further potassium channels open in response to the influx of calcium ions during the action potential. The intracellular concentr... | 7 | Physical Chemistry |
While the definition of sublimation is simple, there is often confusion as to what counts as a sublimation. | 3 | Analytical Chemistry |
For a system of diameter and volume , at constant temperature , the classical canonical partition function
with a scaled coordinate, the free energy is given by:
Combining the above equation with the definition of chemical potential,
we get the chemical potential of a sufficiently large system from (and the fact th... | 7 | Physical Chemistry |
Plasmids may be classified in a number of ways. Plasmids can be broadly classified into conjugative plasmids and non-conjugative plasmids. Conjugative plasmids contain a set of transfer genes which promote sexual conjugation between different cells. In the complex process of conjugation, plasmids may be transferred f... | 1 | Biochemistry |
Eszopiclone, sold under the brand name Lunesta among others, is a medication used in the treatment of insomnia. Evidence supports slight to moderate benefit up to six months. It is taken by mouth.
Common side effects include headache, dry mouth, nausea, and dizziness. Severe side effects may include suicidal thoughts, ... | 4 | Stereochemistry |
Historians debate whether bloomery-based ironworking ever spread to China from the Middle East. One theory suggests that metallurgy was introduced through Central Asia. In 2008, two iron fragments were excavated at the Mogou site, in Gansu. They have been dated to the 14th century BC, belonging to the period of Siwa cu... | 8 | Metallurgy |
Cryptococcus neoformans is a basidiomycetous fungus that grows as a budding yeast in culture and in an infected host. C. neoformans causes life-threatening meningoencephalitis in immune compromised patients. It undergoes a filamentous transition during the sexual cycle to produce spores, the suspected infectious agent.... | 1 | Biochemistry |
Octanoyl-coenzyme A is the endpoint of beta oxidation in peroxisomes. It is produced alongside acetyl-CoA and transferred to the mitochondria to be further oxidized into acetyl-CoA. | 1 | Biochemistry |
The Endocare PerCryo Percutaneous Cryoablation device utilizes argon as a coolant and can be used with four different single cryoprobe configurations with a diameter of either 1.7 mm (~16 gauge) or 2.4 mm (~13 gauge) in diameter .
The Myoscience Iovera is a handheld device that uses nitrous oxide as a coolant and can b... | 1 | Biochemistry |
*Albert Hewett Coons (1912-1978), physician, pathologist and immunologist.
*Cornelia Mitchell Downs (1892–1987), microbiologist and journalist | 1 | Biochemistry |
Most traditional HPLC is performed with the stationary phase attached to the outside of small spherical silica particles (very small beads). These particles come in a variety of sizes with 5 µm beads being the most common. Smaller particles generally provide more surface area and better separations, but the pressure re... | 3 | Analytical Chemistry |
There are two principal classes of fatty acid synthases.
* Type I systems utilise a single large, multifunctional polypeptide and are common to both animals and fungi (although the structural arrangement of fungal and animal syntheses differ). A Type I fatty acid synthase system is also found in the CMN group of bacte... | 1 | Biochemistry |
Photoacids are molecules that upon light absorption undergo a proton transfer to form the photobase.
In these reactions the dissociation occurs in the electronically excited state. After proton transfer and relaxation to the electronic ground state, the proton and acid recombine to form the photoacid again.
Photoacids ... | 5 | Photochemistry |
*Scorpion® probes
*Molecular Beacon probes
*TaqMan® probes
*LNA® (Locked Nucleic Acid) probes
*Cycling Probe Technology (CPT) | 1 | Biochemistry |
Transforming growth factor (, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. F... | 1 | Biochemistry |
The alkylation of tropanes with methyl iodide is a classic example of a Curtin–Hammett scenario in which a major product can arise from a less stable conformation. Here, the less stable conformer reacts via a more stable transition state to form the major product. Therefore, the ground state conformational distribution... | 7 | Physical Chemistry |
Total selenium in selenium yeast can be reliably determined using open acid digestion to extract selenium from the yeast matrix followed by flame atomic absorption spectrometry. Determination of the selenium species selenomethionine can be achieved via proteolytic digestion of selenium yeast followed by high-performanc... | 1 | Biochemistry |
RegulonDB is a database of the regulatory network of gene expression in Escherichia coli K-12. RegulonDB also models the organization of the genes in transcription units, operons and regulons. A total of 120 sRNAs with 231 total interactions which all together regulate 192 genes are also included. RegulonDB was found... | 1 | Biochemistry |
Station ALOHA is a deep water (~4,800 m) location approximately 100 km north of the Hawaiian Island of Oahu. Thus, the region is far enough from land to be free of coastal ocean dynamics and terrestrial inputs, but close enough to a major port (Honolulu) to make relatively short duration (less than five days) near-mon... | 9 | Geochemistry |
The composition of the human body can be classified as follows:
*Water
*Proteins
*Fats (or lipids)
*Hydroxyapatite in bones
*Carbohydrates such as glycogen and glucose
*DNA and RNA
*Inorganic ions such as sodium, potassium, chloride, bicarbonate, phosphate
*Gases mainly being oxygen, carbon dioxide
*Many cofactors.
The... | 1 | Biochemistry |
In 1929, Rinkel proposed a different method to calculate while using the Rüchardt apparatus: he noted that it may be shown that the vertical distance L which the sphere falls before it begin to rise is: , so may be calculated from measured values of L, m, V, P and A.
In 1951, Koehler and later, in 1972 Flammersfeld i... | 7 | Physical Chemistry |
Modafinil has been studied in the treatment of major depressive disorder. In a 2021 systematic review and meta-analysis of randomized controlled trials of psychostimulants for depression, modafinil and other stimulants such as methylphenidate and amphetamines improved depression in traditional meta-analysis. However, w... | 4 | Stereochemistry |
Innate immune system senses intact peptidoglycan and peptidoglycan fragments using numerous PRRs (pattern recognition receptors) that are secreted, expressed intracellularly or expressed on the cell surface. | 1 | Biochemistry |
The enzyme rhodanase (thiosulfate sulfurtransferase) catalyzes the detoxification of cyanide ion by thiosulfate ion by transforming them into thiocyanate ion and sulfite ion:
Sodium thiosulfate has been considered as an empirical treatment for cyanide poisoning, along with hydroxocobalamin. It is most effective in a pr... | 8 | Metallurgy |
Photosystem II (or water-plastoquinone oxidoreductase) is the first protein complex in the light-dependent reactions of oxygenic photosynthesis. It is located in the thylakoid membrane of plants, algae, and cyanobacteria. Within the photosystem, enzymes capture photons of light to energize electrons that are then tran... | 5 | Photochemistry |
Hsalen may be synthesized by the condensation of ethylenediamine and salicylaldehyde.
Complexes of salen with metal cations may be made without isolating it from the reaction mixture. This is possible because the stability constant for the formation of the metal complexes are very high, due to the chelate effect.
:HL +... | 0 | Organic Chemistry |
Using the relationships defined by this equation, the diffusion coefficient of the electroactive species can be determined. Linear plots of i vs. ν provide evidence for a chemically reversible redox process vs the cases where redox causes major structural change in the analyte. For species where the diffusion coeffic... | 3 | Analytical Chemistry |
On 16 December 2014, NASA reported the Curiosity rover detected a "tenfold spike", likely localized, in the amount of methane in the Martian atmosphere. Sample measurements taken "a dozen times over 20 months" showed increases in late 2013 and early 2014, averaging "7 parts of methane per billion in the atmosphere." Be... | 9 | Geochemistry |
In humans, DNA methylation occurs at the 5' position of the pyrimidine ring of the cytosine residues within CpG sites to form 5-methylcytosines. The presence of multiple methylated CpG sites in CpG islands of promoters causes stable silencing of genes. Silencing of a gene may be initiated by other mechanisms, but thi... | 1 | Biochemistry |
Heather D. Willauer (born 1974) is an American analytical chemist and inventor working in Washington, D.C., at the United States Naval Research Laboratory (NRL). Leading a research team, Willauer has patented a method for removing dissolved carbon dioxide (CO) from seawater, in parallel with hydrogen (H) recovered by c... | 3 | Analytical Chemistry |
Common adverse drug reactions (ADRs) associated with the use of dicloxacillin include: diarrhea, nausea, rash, urticaria, pain and inflammation at injection site, superinfection (including candidiasis), allergy, and transient increases in liver enzymes and bilirubin.
On rare occasions, cholestatic jaundice (also referr... | 4 | Stereochemistry |
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