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Concentrated sulfuric acid has a powerful dehydrating property, removing water () from other chemical compounds such as table sugar (sucrose) and other carbohydrates, to produce carbon, steam, and heat. Dehydration of table sugar (sucrose) is a common laboratory demonstration. The sugar darkens as carbon is formed, and...
7
Physical Chemistry
The gel fragment is placed in a dialysis tube that is permeable to fluids but impermeable to molecules at the size of DNA, thus preventing the DNA from passing through the membrane when soaked in TE buffer. An electric field is established around the tubing (in a way similar to gel electrophoresis) long enough so that ...
1
Biochemistry
According to R. Balasubramaniam and A. V. Ramesh Kumar (2003), the pillar shows "excellent" atmospheric corrosion resistance. Ray et al. (1997) analyzed portions of the two smaller fragments. Their analysis revealed the following chemical composition (weight %): Balasubramaniam (2002) also obtained a small portion of t...
8
Metallurgy
Fractional crystallization is the removal and segregation from a melt of mineral precipitates, which changes the composition of the melt. This is one of the most important geochemical and physical processes operating within the Earth's crust and mantle. Fractional crystallization in silicate melts (magmas) is a very co...
9
Geochemistry
Figures 1 and 2 show two-dimensional projections of a phase diagram. In the pressure-temperature phase diagram (Fig. 1) the boiling curve separates the gas and liquid region and ends in the critical point, where the liquid and gas phases disappear to become a single supercritical phase. The appearance of a single phase...
7
Physical Chemistry
In March 1996, a group of scientists at Lawrence Livermore National Laboratory reported that they had serendipitously produced the first identifiably metallic hydrogen for about a microsecond at temperatures of thousands of kelvins, pressures of over , and densities of approximately . The team did not expect to produce...
7
Physical Chemistry
Photo-Induced Cross-Linking of Unmodified Proteins (PICUP) is a protein cross-linking method by visible light irradiation of a photocatalyst in the presence of an electron acceptor and the protein of interest. Irradiation results in a highly reactive protein radical that forms a covalent bond between the amino acid sid...
1
Biochemistry
The Schikorr reaction can occur in the process of anaerobic corrosion of iron and carbon steel in various conditions. Anaerobic corrosion of metallic iron to give iron(II) hydroxide and hydrogen: :3 (Fe + 2 HO → Fe(OH) + H) followed by the Schikorr reaction: :3 Fe(OH) → FeO + 2 HO + H give the following global reaction...
8
Metallurgy
The carboxy-terminal domain (CTD) of RNA polymerase II is that portion of the polymerase that is involved in the initiation of DNA transcription, the capping of the RNA transcript, and attachment to the spliceosome for RNA splicing. The CTD typically consists of up to 52 repeats (in humans) of the sequence Tyr-Ser-Pro-...
1
Biochemistry
Perdeuteration of one component of a multi-component system can provide contrast for neutron scattering experiments, where the contrast obtained by using deuterated solvents is insufficient.
7
Physical Chemistry
In geochemistry, the primitive mantle (also known as the bulk silicate Earth) is the chemical composition of the Earth's mantle during the developmental stage between core-mantle differentiation and the formation of early continental crust. The chemical composition of the primitive mantle contains characteristics of bo...
9
Geochemistry
There are two types of VMATs expressed in humans: VMAT1 and VMAT2. VMAT1 is expressed mainly in large dense-core vesicles (LDCVs) of the peripheral nervous system. VMAT1 may be found in neuroendocrine cells, particularly chromaffin and enterochromaffin granules, which are primarily found in the medulla of the adrenal g...
1
Biochemistry
Development of the chromatogram is done by allowing the solvent to travel down the paper. Here, the mobile phase is placed in a solvent holder at the top. The spot is kept at the top and solvent flows down the paper from above.
3
Analytical Chemistry
Early micro-fossils may have come from a hot world of gases such as methane, ammonia, carbon dioxide, and hydrogen sulfide, toxic to much current life. Analysis of the tree of life places thermophilic and hyperthermophilic bacteria and archaea closest to the root, suggesting that life may have evolved in a hot environm...
9
Geochemistry
Since facultative anaerobes are able to grow in both the presence and absence of oxygen, they can survive in many different environments, adapt easily to changing conditions, and thus have a selective advantage over other bacteria. As a result, most life-threatening pathogens are facultative anaerobes. The ability of f...
1
Biochemistry
In DSSC, electrodes consisted of sintered semiconducting nanoparticles, mainly TiO or ZnO. These nanoparticle DSSCs rely on trap-limited diffusion through the semiconductor nanoparticles for the electron transport. This limits the device efficiency since it is a slow transport mechanism. Recombination is more likely to...
5
Photochemistry
For pure substances so that . In a single phase () condition of a pure component system, two variables (), such as temperature and pressure, can be chosen independently to be any pair of values consistent with the phase. However, if the temperature and pressure combination ranges to a point where the pure component u...
7
Physical Chemistry
The Wikipedia page Metabolic pathway defines a pathway as "a metabolic pathway is a linked series of chemical reactions occurring within a cell". This means that any sequence of reactions can be labeled a metabolic pathway. However, as metabolism was being uncovered, groups of reactions were assigned specific labels, s...
1
Biochemistry
In its earliest form, liquid chromatography was used to separate the pigments of chlorophyll by a Russian botanist. Decades later, other chemists used the procedure for the study of carotins. Liquid chromatography was then used for the isolation of small molecules and organic compounds like amino acids, and most recent...
3
Analytical Chemistry
As at 2017, the company operated the following stations: *Alexandria Station, Northern Territory * Boomarra Station, Queensland * Coolullah Station, Queensland *Coorabulka Station, Queensland * Cungelella Station, Queensland *Glenormiston Station, Queensland * Goldsborough Station, Queensland *Kynuna Station (includes ...
2
Environmental Chemistry
Bis(trimethylsilyl)amine (also known as hexamethyldisilazane and HMDS) is an organosilicon compound with the molecular formula [(CH)Si]NH. The molecule is a derivative of ammonia with trimethylsilyl groups in place of two hydrogen atoms. An electron diffraction study shows that silicon-nitrogen bond length (173.5 pm) a...
0
Organic Chemistry
* left hand side of Navier–Stokes equations minus body force (per unit volume) acting on fluid. * this relation is derived using this relationship which is alternative form of continuity equation
7
Physical Chemistry
According to the rules exposed above, the phenanthrene molecule admits two different resonance structures: one of them presents a single circle in the center of the molecule, with each of the two adjacent rings having two double bonds; the other one has the two peripheral rings each with one circle, and the central rin...
7
Physical Chemistry
In the human genome, all genes get transcribed into RNA because that's how the molecular gene is defined. (See Gene.) The transcriptome consists of coding regions of mRNA plus non-coding UTRs, introns, non-coding RNAs, and spurious non-functional transcripts. Several factors render the content of the transcriptome diff...
1
Biochemistry
Biochemical Predestination is a 1969 book by Dean H. Kenyon and Gary Steinman which argued in support of biochemical evolution. In the book, Kenyon and Steinman conclude that "Life might have been biochemically predestined by the properties of attraction that exist between its chemical parts, especially between amino a...
1
Biochemistry
The stereochemical outcome of a glycosylation reaction may in certain cases be affected by the type of protecting group employed at position 2 of the glycosyl donor. A participating group, typically one with a carboxyl group present, will predominantly result in the formation of a β-glycoside. Whereas a non-participa...
0
Organic Chemistry
Transmetalation involves the exchange of two metals between organic molecules by a redox exchange mechanism. For example, transmetalations often form a reaction between an organolithium reagent and a metal salt.
0
Organic Chemistry
In chemistry, an amine oxide, also known as an amine N-oxide or simply N-oxide, is a chemical compound that has the chemical formula . It contains a nitrogen-oxygen coordinate covalent bond with three additional hydrogen and/or substituent-groups attached to nitrogen. Sometimes it is written as or, alternatively, as ....
0
Organic Chemistry
The term bulk material analyzer is the generic noun for that device which fits around a conveyor belt and conducts real-time elemental analysis of the material on the belt. Other names often found for such a device include belt analyzer, crossbelt analyzer and elemental analyzer. This product first found popularity in...
3
Analytical Chemistry
The so-called inner sphere mechanism entails coordination of the alkene to the metal center. Other characteristics of this mechanism include a tendency for a homolytic splitting of dihydrogen when more electron-rich, low-valent metals are present while electron-poor, high valent metals normally exhibit a heterolytic cl...
0
Organic Chemistry
This category groups pages related to the spliceosome, which is a loose conglomerate of protein and RNA responsible for the correct splicing of mRNA.
1
Biochemistry
Martin Schoell attended University of Munich for his undergraduate career in 1961 and in 1964 attended the University Clausthal, Germany for graduate school where he obtained a PhD in geochemistry. While at the University Clausthal, in 1966 Schoell delivered his Diplomarbeit (Masters Thesis) on the geochemistry of stro...
9
Geochemistry
Primordial fluctuations, density variations in the early universe, are quantified by a power spectrum which gives the power of the variations as a function of spatial scale.
7
Physical Chemistry
The upcasting (up-casting, upstream, or upward casting) is a method of either vertical or horizontal continuous casting of rods and pipes of various profiles (cylindrical, square, hexagonal, slabs etc.) of 8-30mm in diameter. Copper (Cu), bronze (Cu·Sn alloy), nickel alloys are usually used because of greater casting ...
8
Metallurgy
Most applications of hydrothermal liquefaction operate at temperatures between 250-550 °C and high pressures of 5-25 MPa as well as catalysts for 20–60 minutes, although higher or lower temperatures can be used to optimize gas or liquid yields, respectively. At these temperatures and pressures, the water present in the...
0
Organic Chemistry
In a closed system, there is a difference observed in the anomeric effect for different substituents on a cyclohexane or tetrahydropyran ring (Y=Oxygen). When X=OH, the generic anomeric effect can be seen, as previously explained. When X=CN, the same results are seen, where the equatorial position is preferred on the c...
7
Physical Chemistry
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. mRNA is created during the process of transcription, where an enzyme (RNA polymerase) converts the gene int...
1
Biochemistry
ETF-QO consists of one structural domain with three functional domains packed in close proximity: a FAD domain, a 4Fe4S cluster domain, and a UQ-binding domain. FAD is in an extended conformation and is buried deeply within its functional domain. Multiple hydrogen bonds and a positive helix dipole modulate the redox po...
1
Biochemistry
One of main contributions of SNPs in clinical research is genome-wide association study (GWAS). Genome-wide genetic data can be generated by multiple technologies, including SNP array and whole genome sequencing. GWAS has been commonly used in identifying SNPs associated with diseases or clinical phenotypes or traits. ...
1
Biochemistry
The primary sequence for FAM227B is isoform 1 with accession number: NP_689860.2. It is 508 amino acids long. There are 30 isoforms. The molecular weight is 59.9kD and the isoelectric point is predicted to be high, around 10. Compared to other proteins in humans, FAM227B has high abundance of Phenylalanine and Glycine ...
1
Biochemistry
Orthophosphate ion can be conveniently thermometrically titrated with magnesium ions in the presence of ammonium ion. An aliquot of sample is buffered to approximately pH10 with an NH/NHCl solution. The reaction: : Mg + NH + PO ↔ MgNHPO↓ Is exothermic. CV's of under 0.1 have been achieved in test applications. The proc...
3
Analytical Chemistry
Annulenes are monocyclic hydrocarbons that contain the maximum number of non-cumulated or conjugated double bonds (mancude). They have the general formula CH (when n is an even number) or CH (when n is an odd number). The IUPAC accepts the use of annulene nomenclature in naming carbocyclic ring systems with 7 or more c...
7
Physical Chemistry
Sterlite Industries ("Sterlite"), a subsidiary of Vedanta Resources, built a copper smelter in Tuticorin using an ISASMELT furnace and Peirce-Smith converters. The smelter was commissioned in 1996 and was designed to produce 60,000 t/y of copper (450,000 t/y of copper concentrate), but by increasing the oxygen content ...
8
Metallurgy
Mediator is involved in "looping" of chromatin, which brings distant regions of a chromosome into closer physical proximity. The ncRNA-a mentioned above is involved in such looping. Enhancer RNAs (eRNAs) can function similarly. In addition to the looping of euchromatin, mediator appears to be involved in formation or m...
1
Biochemistry
A vacuum ceramic filter is designed to separate liquids from solids for dewatering of ore concentrates purposes. The device consists of a rotator, slurry tank, ceramic filter plate, distributor, discharge scraper, cleaning device, frame, agitating device, pipe system, vacuum system, automatic acid dosing system, automa...
3
Analytical Chemistry
It has been established that cationic macromolecules in general destabilize the cell membrane, which can lead to lysis and cell death. The common conclusion present in current work echoes this observation: increasing dendrimer molecular weight and surface charge (both being generation-dependent) increases their cytotox...
6
Supramolecular Chemistry
Sir Robert Howson Pickard FRS (27 September 1874 – 18 October 1949) was a chemist who did pioneering work in stereochemistry and also for the cotton industry in Lancashire. He was also involved in educational administration and was Vice Chancellor of the University of London from 1937-1939. He was Principal of Batterse...
4
Stereochemistry
AKT is downstream to PI3K and is inhibited by Ipatasertib. Akt is an AGC-family kinase and a central, integral signaling node of the PAM pathway. There are three Akt isozymes, Akt1, Akt2 and Akt3. Small-molecule inhibitors of Akt1 could be especially useful to target tumors with a high prevalence of Akt1 E17K activatin...
1
Biochemistry
The term polyol is used for various chemistries of the molecular backbone. Polyols may be reacted with diisocyanates or polyisocyanates to produce polyurethanes. MDI finds considerable use in PU foam production. Polyurethanes are used to make flexible foam for mattresses and seating, rigid foam insulation for refrigera...
7
Physical Chemistry
In chemistry, an arsaalkyne is chemical compound with a triple bond between carbon and arsenic. These organoarsenic compounds are rare, especially in comparison with the phosphaalkynes. The parent HCAs has been characterized spectroscopically, otherwise the only arsaalkynes have bulky organic substituents.
0
Organic Chemistry
The metal reagents used in this reaction include lithium bromide and silver acetate. In this method, the metal coordinates to the nitrogen in order to activate the substrate for deprotonation. Another way to form azomethine ylides from imines is by prototropy and by alkylation.
0
Organic Chemistry
Boyles law states that at constant temperature' the volume of a given mass of a dry gas is inversely proportional to its pressure. Most gases behave like ideal gases at moderate pressures and temperatures. The technology of the 17th century could not produce very high pressures or very low temperatures. Hence, the law ...
7
Physical Chemistry
Once the presence of certain substances in a sample is known, the study of their absolute or relative abundance could help in determining specific properties. Knowing the composition of a sample is very important, and several ways have been developed to make it possible, like gravimetric and volumetric analysis. Gravim...
3
Analytical Chemistry
In epigenetics, proline isomerization is the effect that cis-trans isomerization of the amino acid proline has on the regulation of gene expression. Similar to aspartic acid, the amino acid proline has the rare property of being able to occupy both cis and trans isomers of its prolyl peptide bonds with ease. Peptidyl-p...
4
Stereochemistry
One of the first examples of encapsulating a structure at the molecular level was demonstrated by Donald Cram and coworkers; they were able to isolate highly unstable, antiaromatic cyclobutadiene at room temperature by encapsulating it within a hemicarcerand. Isolation of cyclobutadiene allowed chemists to experimental...
6
Supramolecular Chemistry
The phenotype of each individual is modeled as the gene expression pattern at time . It is represented by a state vector in this model. whose element denotes the expression state of gene i at time t. In the original Wagner model, where 1 represents the gene is expressed while -1 implies the gene is not expressed. T...
1
Biochemistry
Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an enzyme. Enzyme inhibition can refer to * the inhibition of the expression of the enzyme by another molecule * interference at the enzyme-level, basically with how the enzyme works. This can be comp...
1
Biochemistry
Solar-blind imaging can be used to detect corona discharge, in electrical infrastructure. Missile exhaust can be detected from the troposphere or ground. Also when looking down on the Earth from space, the Earth appears dark in this range, so rockets can be easily detected from above once they pass the ozone layer. Isr...
5
Photochemistry
Some necessary apparatus include: * crucible (or similar porcelain or metal dishes) * muffled furnace * hot plate * the sample
3
Analytical Chemistry
Other than standard fluorescence optical tweezers are now being built with multiple color Confocal, Widefield, STED, FRET, TIRF or IRM. This allows applications such as measuring: protein/DNA localization binding, protein folding, condensation, motor protein force generation, visualization of cytoskeletal filaments and...
1
Biochemistry
Desorption/ionization on silicon (DIOS) is a soft laser desorption method used to generate gas-phase ions for mass spectrometry analysis. DIOS is considered the first surface-based surface-assisted laser desorption/ionization (SALDI-MS) approach. Prior approaches were accomplished using nanoparticles in a matrix of gly...
3
Analytical Chemistry
Deuterium has been shown to lengthen the period of oscillation of the circadian clock when dosed in rats, hamsters, and Gonyaulax dinoflagellates. In rats, chronic intake of 25% DO disrupts circadian rhythmicity by lengthening the circadian period of suprachiasmatic nucleus-dependent rhythms in the brain's hypothalamus...
9
Geochemistry
TEs are found in almost all life forms, and the scientific community is still exploring their evolution and their effect on genome evolution. It is unclear whether TEs originated in the last universal common ancestor, arose independently multiple times, or arose once and then spread to other kingdoms by horizontal gene...
1
Biochemistry
Thermoplastic starch represents the most widely used bioplastic, constituting about 50 percent of the bioplastics market. Simple starch bioplastic film can be made at home by gelatinizing starch and solution casting. Pure starch is able to absorb humidity, and is thus a suitable material for the production of drug cap...
7
Physical Chemistry
SCCmec, or staphylococcal cassette chromosome mec, is a mobile genetic element of Staphylococcus bacterial species. This genetic sequence includes the mecA gene coding for resistance to the antibiotic methicillin and is the only known way for Staphylococcus strains to spread the gene in the wild by horizontal gene tran...
1
Biochemistry
By combining substances with pK values differing by only two or less and adjusting the pH, a wide range of buffers can be obtained. Citric acid is a useful component of a buffer mixture because it has three pK values, separated by less than two. The buffer range can be extended by adding other buffering agents. The fol...
7
Physical Chemistry
Phosphine is used for pest control, but its usage is strictly regulated due to high toxicity. Gas from phosphine has high mortality rate and has caused deaths in Sweden and other countries. Because the previously popular fumigant methyl bromide has been phased out in some countries under the Montreal Protocol, phosphin...
0
Organic Chemistry
Siderophores have applications in medicine for iron and aluminum overload therapy and antibiotics for improved targeting. Understanding the mechanistic pathways of siderophores has led to opportunities for designing small-molecule inhibitors that block siderophore biosynthesis and therefore bacterial growth and virulen...
1
Biochemistry
Only one example is known, bis(trifluoromethyl)phosphinous acid, (CF)POH. It is prepared in several steps from phosphorus trichloride (Et = ethyl): :PCl + 2 EtNH → PClNEt + EtNHCl :2 P(NEt) + PClNEt + 2 CFBr → P(CF)NEt + 2 BrClP(NEt) :P(CF)NEt + HO → P(CF)OH + HNEt
0
Organic Chemistry
In crystallography, a Strukturbericht designation or Strukturbericht type is a system of detailed crystal structure classification by analogy to another known structure. The designations were intended to be comprehensive but are mainly used as supplement to space group crystal structures designations, especially histor...
3
Analytical Chemistry
In two-dimensional space there are 5 Bravais lattices, grouped into four lattice systems, shown in the table below. Below each diagram is the Pearson symbol for that Bravais lattice. Note: In the unit cell diagrams in the following table the lattice points are depicted using black circles and the unit cells are depicte...
3
Analytical Chemistry
In cycloalkanes, each carbon is bonded nonpolar covalently to two carbons and two hydrogen. The carbons have sp hybridization and should have ideal bond angles of 109.5°. Due to the limitations of cyclic structure, however, the ideal angle is only achieved in a six carbon ring — cyclohexane in chair conformation....
7
Physical Chemistry
Straight-chain alkanes take the suffix "-ane" and are prefixed depending on the number of carbon atoms in the chain, following standard rules. The first few are: For example, the simplest alkane is methane, and the nine-carbon alkane is named nonane. The names of the first four alkanes were derived from methanol, eth...
0
Organic Chemistry
Hicks' research focuses largely on the development and implementation of mass spectrometric methods for protein identification and characterization. Recent work in the Hicks Lab has focused primarily on two areas. The first is the study of post-translational modifications and their role in regulation and development. T...
3
Analytical Chemistry
Iodic acid crystallises from acidic solution as orthorhombic α- in space group P222. The structure consists of pyramidal molecules linked by hydrogen bonding and intermolecular iodine-oxygen interactions. The I=O bond lengths are 1.81 Å while the I–OH distance is 1.89 Å. Several other polymorphs have been reported, inc...
3
Analytical Chemistry
P1 is a temperate bacteriophage that infects Escherichia coli and some other bacteria. When undergoing a lysogenic cycle the phage genome exists as a plasmid in the bacterium unlike other phages (e.g. the lambda phage) that integrate into the host DNA. P1 has an icosahedral head containing the DNA attached to a contra...
1
Biochemistry
There are several methods for preparing aldehydes, but the dominant technology is hydroformylation. Illustrative is the generation of butyraldehyde by hydroformylation of propene:
0
Organic Chemistry
Liquid hydrophilic chemicals complexed with solid chemicals can be used to optimize solubility of hydrophobic chemicals.
6
Supramolecular Chemistry
In chemistry imidines are a rare functional group, being the nitrogen analogues of anhydrides and imides. They were first reported by Adolf Pinner in 1883, but did not see significant investigation until the 1950s, when Patrick Linstead and John Arthur Elvidge developed a number of compounds. Imidines may be prepared i...
0
Organic Chemistry
Fluorescent materials are also very widely used in numerous applications in molecular biology, often as "tags" which bind themselves to a substance of interest (for example, DNA), so allowing their visualization. Thousands of moth and insect collectors all over the world use various types of black lights to attract mot...
5
Photochemistry
The ionization equilibrium of an acid or a base is affected by a solvent change. The effect of the solvent is not only because of its acidity or basicity but also because of its dielectric constant and its ability to preferentially solvate and thus stabilize certain species in acid-base equilibria. A change in the solv...
7
Physical Chemistry
The American Society for Biochemistry and Molecular Biology (ASBMB) is a learned society that was founded on December 26, 1906, at a meeting organized by John Jacob Abel (Johns Hopkins University). The roots of the society were in the American Physiological Society, which had been formed some 20 years earlier. ASBMB is...
1
Biochemistry
The physical and mathematical basics of electron charge transfer absent chemical bonds leading to pseudocapacitance was developed by Rudolph A. Marcus. Marcus Theory explains the rates of electron transfer reactions—the rate at which an electron can move from one chemical species to another. It was originally formulate...
7
Physical Chemistry
In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other organic substituent. The functional group itself is referred to as either a thiol group or a sulfhydryl group, or a sulfanyl group. Thiols are the sulfur analogue of alcohols (that i...
0
Organic Chemistry
In the late 1960s it was discovered that illuminated organic dyes can generate electricity at oxide electrodes in electrochemical cells. In an effort to understand and simulate the primary processes in photosynthesis the phenomenon was studied at the University of California at Berkeley with chlorophyll extracted from ...
5
Photochemistry
After ingestion, ethyl eicosapentaenoic acid (E-EPA) is metabolized to eicosapentaenoic acid (EPA). EPA is absorbed in the small intestine and enters circulation. Peak plasma concentration occurs about five hours after ingestion, and the half-life is about 89 hours. EPA is lipolyzed mostly in the liver.
1
Biochemistry
A pheromone (from Greek phero "to bear" + hormone from Greek – "impetus") is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting outside the body of the secreting individual to impact the behavior of the receiving individual. ...
1
Biochemistry
A gasket used in a diamond anvil cell experiment is a thin metal foil, typically 0.3 mm in thickness, which is placed in between the diamonds. Desirable materials for gaskets are strong, stiff metals such as rhenium or tungsten. Steel is frequently used as a cheaper alternative for low pressure experiments. The above-m...
7
Physical Chemistry
A method that is the less well-known is the metabisulfite method, in which metabisulfite is placed at the bottom of a beaker and 12.6 molar concentration hydrochloric acid is added. The resulting gas is bubbled through nitric acid, which will release brown/red vapors of nitrogen dioxide as the reaction proceeds. The co...
7
Physical Chemistry
The biosynthesis of N-linked glycans occurs via 3 major steps: #Synthesis of dolichol-linked precursor oligosaccharide #En bloc transfer of precursor oligosaccharide to protein #Processing of the oligosaccharide Synthesis, en bloc transfer and initial trimming of precursor oligosaccharide occurs in the endoplasmic reti...
0
Organic Chemistry
In a common FPLC strategy, a resin is chosen that the protein of interest will bind to by a charge interaction while in buffer A (the running buffer) but become dissociated and return to solution in buffer B (the elution buffer). A mixture containing one or more proteins of interest is dissolved in 100% buffer A and pu...
3
Analytical Chemistry
Exogenous antigens are antigens that have entered the body from the outside, for example, by inhalation, ingestion or injection. The immune system's response to exogenous antigens is often subclinical. By endocytosis or phagocytosis, exogenous antigens are taken into the antigen-presenting cells (APCs) and processed in...
1
Biochemistry
An STR multiplex system is used to identify specific short tandem repeats (STRs). STR polymorphisms are genetic markers that may be used to identify a DNA sequence. The FBI analyses 13 specific STR loci for their database. These may be used in many areas of genetics in addition to their forensic uses. One can think of ...
1
Biochemistry
Classically, it converts carboxylic acids to acyl chlorides: The reaction mechanism has been investigated:
0
Organic Chemistry
Upon heating to 420 °C, it rearranges to form the meta isomer. The para isomer is produced by heating to temperatures above 600 °C.
7
Physical Chemistry
The Golm Metabolome Database (GMD) is a gas chromatography (GC) – mass spectrometry (MS) reference library dedicated to metabolite profiling experiments and comprises mass spectral and retention index (RI) information for non-annotated mass spectral tags (MSTs, mass spectral information with retention time attached ind...
0
Organic Chemistry
These circuits can be modelled in silico to predict the dynamics of a genetic system. Having constructed a computational model of the natural circuit of interest, one can use the model to make testable predictions about circuit performance. When designing a synthetic circuit for a specific engineering task, a model is ...
1
Biochemistry
In chemistry, autoprotolysis is a chemical reaction in which a proton is transferred between two identical molecules, one of which acts as a Brønsted acid, releasing a proton which is accepted by the other molecule acting as a Brønsted base. For example, water undergoes autoprotolysis in the self-ionization of water r...
7
Physical Chemistry
Luciferases can be produced in the lab through genetic engineering for a number of purposes. Luciferase genes can be synthesized and inserted into organisms or transfected into cells. As of 2002, mice, silkworms, and potatoes are just a few of the organisms that have already been engineered to produce the protein. In ...
1
Biochemistry
Prelog attended elementary school in Sarajevo, but in 1915, as a child, Prelog moved to Zagreb (then part of the Austro-Hungary) with his parents. In Zagreb he graduated from elementary school. At first, he attended gymnasium in Zagreb, but soon afterwards, his father got a job in Osijek, so he continued his education ...
4
Stereochemistry