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A dipole can align to stabilize or destabilize the formation or loss of a charge, thereby decreasing (if stabilized) or increasing (if destabilized) the activation barrier to a chemical event. Field effects can therefore tune the acidity or basicity of bonds within their fields by donating or withdrawing charge density... | 7 | Physical Chemistry |
An isotopic tracer, (also "isotopic marker" or "isotopic label"), is used in chemistry and biochemistry to help understand chemical reactions and interactions. In this technique, one or more of the atoms of the molecule of interest is substituted for an atom of the same chemical element, but of a different isotope (lik... | 7 | Physical Chemistry |
In the future alternative marker technologies will need to be used more often to, at the least, assuage concerns about their persistence into the final product. It is also possible that markers will be replaced entirely by future techniques which use removable markers, and others which do not use markers at all, instea... | 1 | Biochemistry |
In freshwater or estuarine systems close to land, nitrate can reach concentrations that are lethal to fish. While nitrate is much less toxic than ammonia, levels over 30 ppm of nitrate can inhibit growth, impair the immune system and cause stress in some aquatic species. Nitrate toxicity remains a subject of debate.
In... | 0 | Organic Chemistry |
For the past 30 years, isothermal titration calorimetry has been used in a wide array of fields. In the old days, this technique was used to determine fundamental thermodynamic values for basic small molecular interactions. In recent years, ITC has been used in more industrially applicable areas, such as drug discovery... | 7 | Physical Chemistry |
Astressin-B is a nonselective corticotropin releasing hormone antagonist that reduces the synthesis of adrenocorticotropic hormone and cortisol.
It reduces the synthesis of adrenocorticotropic hormone and improves the sexual drive of rats under stressing conditions.
Astressin-B is able to delay the emptying of solid fo... | 1 | Biochemistry |
In the sense that DNA replication must occur if genetic material is to be provided for the progeny of any cell, whether somatic or reproductive, the copying from DNA to DNA arguably is the fundamental step in information transfer. A complex group of proteins called the replisome performs the replication of the informat... | 1 | Biochemistry |
Archaeal transcription shares eukaryotic and bacterial ties. With eukaryotes, it shares similarities with its initiation factors that help transcription identify appropriate sequences such as TATA box homologs as well as factors that maintain transcription elongation. However, additional transcription factors similar t... | 1 | Biochemistry |
β-Oxidation of unsaturated fatty acids poses a problem since the location of a cis-bond can prevent the formation of a trans-Δ bond which is essential for continuation of β-Oxidation as this conformation is ideal for enzyme catalysis. This is handled by additional two enzymes, Enoyl CoA isomerase and 2,4 Dienoyl CoA re... | 1 | Biochemistry |
Gene therapy is a promising treatment for a number of diseases where a "normal" gene carried by the vector is inserted into the genome, to replace an "abnormal" gene or supplement the expression of particular gene. Viral vectors are generally used but other nonviral methods of delivery are being developed. The treatmen... | 1 | Biochemistry |
The term amphibolism () is used to describe a biochemical pathway that involves both catabolism and anabolism. Catabolism is a degradative phase of metabolism in which large molecules are converted into smaller and simpler molecules, which involves two types of reactions. First, hydrolysis reactions, in which catabolis... | 1 | Biochemistry |
Sodium amide induces the loss of two equivalents of hydrogen bromide from a vicinal dibromoalkane to give a carbon–carbon triple bond, as in a preparation of phenylacetylene.
Usually two equivalents of sodium amide yields the desired alkyne. Three equivalents are necessary in the preparation of a terminal alkynes becau... | 0 | Organic Chemistry |
The first step in Gateway cloning is the preparation of a Gateway Entry clone. There are a few different ways to make entry clone.
# Gateway attB1 and attB2 sequences are added to the 5 and 3 end of a gene fragment, respectively, using gene-specific PCR primers and PCR amplification. The PCR amplification products are... | 1 | Biochemistry |
Thermal spraying techniques are coating processes in which melted (or heated) materials are sprayed onto a surface. The "feedstock" (coating precursor) is heated by electrical (plasma or arc) or chemical means (combustion flame).
Thermal spraying can provide thick coatings (approx. thickness range is 20 microns to sev... | 8 | Metallurgy |
* R.J. Talling, R.J. Dashwood, M. Jackson, D. Dye, [https://www.sciencedirect.com/science/article/pii/S1359645408008082 On the mechanism of superelasticity in Gum metal], Acta Materialia, Volume 57, Issue 4, 2009, Pages 1188-1198, ISSN 1359-6454, doi: 10.1016/j.actamat.2008.11.013.
* N.G. Jones, R.J. Dashwood, M. Jacks... | 8 | Metallurgy |
It is important to note that A-values do not predict the physical size of a molecule, only the steric effect. For example, the tert-butyl group (A-value=4.9) has a larger A-value than the trimethylsilyl group (A-value=2.5), yet the tert-butyl group actually occupies less space. This difference can be attributed to the... | 4 | Stereochemistry |
In addition to the scanning forms of Fourier-transform spectrometers, there are a number of stationary or self-scanned forms. While the analysis of the interferometric output is similar to that of the typical scanning interferometer, significant differences apply, as shown in the published analyses. Some stationary for... | 7 | Physical Chemistry |
Metastasis is a major cause of cancer deaths, and strategies to prevent or halt invasion are lacking. One study showed that autocrine PDGFR signaling plays an essential role in epithelial-mesenchymal transition (EMT) maintenance in vitro, which is known to correlate well with metastasis in vivo. The authors showed that... | 1 | Biochemistry |
In the iron and steel industry, direct reduction is a set of processes for obtaining iron from iron ore, by reducing iron oxides without melting the metal. The resulting product is pre-reduced iron ore.
Historically, direct reduction was used to obtain a burr in a low furnace. At the beginning of the 20th century, this... | 8 | Metallurgy |
There is no limit to the number of possible organic reactions and mechanisms. However, certain general patterns are observed that can be used to describe many common or useful reactions. Each reaction has a stepwise reaction mechanism that explains how it happens, although this detailed description of steps is not alwa... | 0 | Organic Chemistry |
Abiotic factors that can damage plants include heat, freezing, flooding, lightning strikes, ozone gas, and pollutant chemicals.
Heat can kill any plant, given a sufficient temperature. Alpine plants tend to die at around 47 Celsius; temperate plants at around 51 Celsius; and tropical plants at nearly 58 Celsius: but th... | 1 | Biochemistry |
IUPAC nomenclature is used in scientific publications, and in writings where precise identification of the substance is important. In naming simple alcohols, the name of the alkane chain loses the terminal e and adds the suffix -ol, e.g., as in "ethanol" from the alkane chain name "ethane". When necessary, the position... | 0 | Organic Chemistry |
Detonation gun spraying like any other industrial process carries with it a number of safety hazards that need to be managed correctly in order to ensure operator safety whilst in use. These safety precautions primarily fall into the following categories and the hazard minimisation techniques suggested, in some cases h... | 8 | Metallurgy |
The COLUMBUS PROGRAMS maintain a program unique style that distinguish itself from most other quantum chemistry programs.
The program suite is a collection of a number of programs coded in Fortran, each can be executed independently. These programs communicate through files. Perl scripts are provided to prepare input... | 7 | Physical Chemistry |
The total Hamiltonian of an atom in a magnetic field is
where is the unperturbed Hamiltonian of the atom, and is the perturbation due to the magnetic field:
where is the magnetic moment of the atom. The magnetic moment consists of the electronic and nuclear parts; however, the latter is many orders of magnitude smal... | 7 | Physical Chemistry |
Precipitation of minerals is affected by water solubility within silicate melts, which typically exists as hydroxyl groups bound to Si or Group 1 and Group 2 cations in concentrations ranging from approximately 6-7 wt. %. Specifically, the equilibrium of water and dissolved oxygen yields hydroxides, where the K has bee... | 9 | Geochemistry |
With non-covalent imprinting, interaction forces between template molecule and functional monomer are the same as the interaction forces between the polymer matrix and analyte. The forces involved in this procedure can include hydrogen bonds, dipole dipole interactions, and induced dipole forces. This method is the mos... | 6 | Supramolecular Chemistry |
In 2005, the water supply to the city of Harbin in China with a population of almost nine million people, was cut off because of a major benzene exposure. Benzene leaked into the Songhua River, which supplies drinking water to the city, after an explosion at a China National Petroleum Corporation (CNPC) factory in the ... | 2 | Environmental Chemistry |
Eslicarbazepine acetate was developed by the Portuguese pharmaceutical company Bial. In early 2009, Bial sold the marketing rights in Europe to the Japanese company Eisai. The drug was approved in the European Union in April 2009 under the trade names Zebinix and Exalief, but was marketed only under the first name. In ... | 4 | Stereochemistry |
At 16 billion Scoville units, resiniferatoxin is rather toxic and can inflict chemical burns in minute quantities. The primary action of resiniferatoxin is to activate sensory neurons responsible for the perception of pain. It is currently the most potent TRPV1 agonist known, with ~500x higher binding affinity for TRPV... | 0 | Organic Chemistry |
In 2021, dextrorphan was identified in >75% of sludge samples taken from 12 wastewater treatment plants in California. The same study associated dextrorphan with estrogenic activity by using predictive modelling, before observing it in in vitro. | 4 | Stereochemistry |
Cells secrete ATP to communicate with other cells in a process called purinergic signalling. ATP serves as a neurotransmitter in many parts of the nervous system, modulates ciliary beating, affects vascular oxygen supply etc. ATP is either secreted directly across the cell membrane through channel proteins or is pumpe... | 1 | Biochemistry |
Chitin-glucan complex (CGC) is a copolymer (polysaccharide) that makes up fungal cell walls, consisting of covalently-bonded chitin and branched 1,3/1,6-ß-D-glucan. CGCs are alkaline-insoluble. Different species of fungi have different structural compositions of chitin and β-glucan making up the CGCs in their cell wa... | 1 | Biochemistry |
Nervous system control over hormone release is based in the hypothalamus, from which the neurons that populate the pariventricular and arcuate nuclei originate. These neurons project to the median eminence, where they secrete releasing hormones into the hypophysial portal system connecting the hypothalamus with the pi... | 1 | Biochemistry |
Polymers that can crystallize are (with the exception of PP) guarantee to obtain this effect, mainly due to their ordering capacity, which is reflected in the crystallinity, the crystals have affinity for their constituent elements and form new bonds these achieve anchoring forces that give stability to the temporary f... | 7 | Physical Chemistry |
Anoxic conditions result from a combination of environmental conditions including density stratification, inputs of organic material or other reducing agents, and physical barriers to water circulation. In fjords, shallow sills at the entrance may prevent circulation, while at continental boundaries, circulation may b... | 9 | Geochemistry |
Copper indium gallium selenide (CIGS) is a direct band gap material. It has the highest efficiency (~20%) among all commercially significant thin film materials (see CIGS solar cell). Traditional methods of fabrication involve vacuum processes including co-evaporation and sputtering. Recent developments at IBM and Nano... | 7 | Physical Chemistry |
Yulia Sister entered the Department of Chemistry of the University of Kishinev in the fall 1954. While asked by Professor , who interviewed the applicants to the Department, why she has chosen this Department, she explained that thanks to her school teacher she fell in love with chemistry. At the University Yulia was i... | 3 | Analytical Chemistry |
The development of an analytical instrument that utilizes the reduction-oxidation (redox) chemistry of oxygen in the presence of dissimilar metal electrodes was introduced during the 1950s. This redox electrode (also known as dissolved oxygen sensor) utilized an oxygen-permeable membrane to allow the diffusion of the g... | 3 | Analytical Chemistry |
One mechanism proposed for the oxidation of adsorbed organics from solution is the production of hydroxyl radical by the valence holes migrating to the surface and reacting with adsorbed hydroxyl groups, resulting in a very strong oxidizing radical. Identification of hydroxylated oxidation intermediates and hydroxyl ra... | 7 | Physical Chemistry |
Because of the ambiguity of the term valence, other notations are currently preferred. Beside the lambda notation, as used in the IUPAC nomenclature of inorganic chemistry, oxidation state is a more clear indication of the electronic state of atoms in a molecule.
The oxidation state of an atom in a molecule gives the n... | 3 | Analytical Chemistry |
An example of the Grignard reaction is a key step in the (non-stereoselective) industrial production of Tamoxifen (currently used for the treatment of estrogen receptor positive breast cancer in women): | 0 | Organic Chemistry |
Leopold Ružička (; born Lavoslav Stjepan Ružička; 13 September 1887 – 26 September 1976) was a Croatian-Swiss scientist and joint winner of the 1939 Nobel Prize in Chemistry "for his work on polymethylenes and higher terpenes" "including the first chemical synthesis of male sex hormones." He worked most of his life in... | 0 | Organic Chemistry |
The major disadvantage to the DSSC design is the use of the liquid electrolyte, which has temperature stability problems. At low temperatures the electrolyte can freeze, halting power production and potentially leading to physical damage. Higher temperatures cause the liquid to expand, making sealing the panels a serio... | 5 | Photochemistry |
The Yukawa–Tsuno equation, first developed in 1959, is a linear free-energy relationship in physical organic chemistry. It is a modified version of the Hammett equation that accounts for enhanced resonance effects in electrophilic reactions of para- and meta-substituted organic compounds. This equation does so by intro... | 7 | Physical Chemistry |
Shq1, a protein thought to play a role in the stabilization and/or production of box H/ACA snoRNA, is still uncharacterized. It has been proposed that Shq1, along with Naf1p, is involved in the initial steps of the biogenesis of H/ACA box snoRNPs (box H/ACA snoRNAs form complexes with proteins, thereby forming snoRNPs... | 1 | Biochemistry |
In July 2022, concerns were raised by Matthew Schrag, a Vanderbilt University neuroscientist, that certain images in the 2006 Nature paper were manipulated in the paper co-authored by Ashes postdoctoral Sylvain Lesné, whom she hired in 2002. These concerns were published in an article in Science authored by Charles Pil... | 1 | Biochemistry |
* This is an irreversible physical immobilization technique which can be considered as a physical restriction of enzyme in a specified area/space. It can be used for raising mechanical stability and can be also used for the reduction of leaching events of enzymes. Since the enzyme in this process does not interact chem... | 4 | Stereochemistry |
Because peanut agglutinin specifically binds a particular carbohydrate sequence it finds use in a range of methods for cell biology and biochemistry. For example in PNA-affinity chromatography the binding specificity of peanut agglutinin is used to isolate glycosylated molecules which have the sugar sequence Gal-β(1-3)... | 1 | Biochemistry |
The ores of base metals are often sulfides. In recent centuries, reverberatory furnaces have been used to keep the charge being smelted separately from the fuel. Traditionally, they were used for the first step of smelting: forming two liquids, one an oxide slag containing most of the impurities, and the other a sulfid... | 8 | Metallurgy |
In biochemistry, the Corey-Pauling rules are a set of three basic statements that govern the secondary nature of proteins, in particular, the CO-NH peptide link. They were originally proposed by Robert Corey and Linus Pauling.
The rules are as follows:
#The atoms in a peptide link all lie on the same plane.
#The nitrog... | 4 | Stereochemistry |
Anthocyanins are thought to be subject to physiochemical degradation in vivo and in vitro. Structure, pH, temperature, light, oxygen, metal ions, intramolecular association, and intermolecular association with other compounds (copigments, sugars, proteins, degradation products, etc.) generally are known to affect the c... | 3 | Analytical Chemistry |
Single colour reflectometry (SCORE), formerly known as imaging Reflectometric Interferometry (iRIf) and 1-lambda Reflectometry, is a physical method based on interference of monochromatic light at thin films, which is used to investigate (bio-)molecular interactions. The obtained binding curves using SCORE provide deta... | 7 | Physical Chemistry |
Progesterone is a naturally occurring pregnane steroid and is also known as pregn-4-ene-3,20-dione. It has a double bond (4-ene) between the C4 and C5 positions and two ketone groups (3,20-dione), one at the C3 position and the other at the C20 position. | 0 | Organic Chemistry |
Chlorprothixene, sold under the brand name Truxal among others, is a typical antipsychotic of the thioxanthene group. | 4 | Stereochemistry |
Terpenes and terpenoids of many kinds are found in resinous plants such as the conifers. They are aromatic and serve to repel herbivores. Their scent makes them useful in essential oils, whether for perfumes such as rose and lavender, or for aromatherapy. Some have had medicinal uses: thymol is an antiseptic and was on... | 1 | Biochemistry |
After recognizing an antigen, an antigen-presenting cell such as the macrophage or B lymphocyte engulfs it completely by a process called phagocytosis. The engulfed particle, along with some material surrounding it, forms the endocytic vesicle (the phagosome), which fuses with lysosomes. Within the lysosome, the antige... | 1 | Biochemistry |
Also known as Transposable element#DNA transposons DNA transposons], these employ a strategy by which the transposon is excised from its position via transposase, and re-integrated elsewhere in the genome. These can be identified by the following:
* TIRs, terminal inverted repeats, which allow transposase to recognize ... | 1 | Biochemistry |
The hammerhead titanothere (Angtsìk in Navi) is a large hexapodal herbivore whose massive, low-slung head features bony projections on either side of the skull, similar to those of hammerhead sharks and their bodies resemble the Brontotheres of Earth. These protrusions are often used to push and destroy objects: a sing... | 1 | Biochemistry |
Orgel diagrams are correlation diagrams which show the relative energies of electronic terms in transition metal complexes, much like Tanabe–Sugano diagrams. They are named after their creator, Leslie Orgel. Orgel diagrams are restricted to only show weak field (i.e. high spin) cases, and offer no information about str... | 7 | Physical Chemistry |
These are extremely light-sensitive vacuum tubes with a coated photocathode inside the envelope. The photo cathode contains combinations of materials such as cesium, rubidium, and antimony specially selected to provide a low work function, so when illuminated even by very low levels of light, the photocathode readily r... | 7 | Physical Chemistry |
Sulfate reduction in the seabed is strongly focused toward near-surface sediments with high depositional rates along the ocean margins. The benthic marine sulfur cycle is therefore sensitive to anthropogenic influence, such as ocean warming and increased nutrient loading of coastal seas. This stimulates photosynthetic ... | 9 | Geochemistry |
PCBs originating from Monsanto Chemical Company in Anniston, Alabama, were dumped into Snow Creek, which then spread to Choccolocco Creek, then Logan Martin Lake. In the early 2000s, class action lawsuits were settled by local land owners, including those on Logan Martin Lake, and Lay Reservoir (downstream on the Coosa... | 2 | Environmental Chemistry |
UDP-glucuronic acid is a sugar used in the creation of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid (except in primates and guinea pigs). It also participates in the heme degradation process of human.
It is made from UDP-glucose by UDP-glucose 6-dehydrogenase (EC 1.1.1.22) using NAD+ as a... | 1 | Biochemistry |
The Wong–Sandler mixing rule is a thermodynamic mixing rule used for vapor–liquid equilibrium and liquid-liquid equilibrium calculations.
__TOC__ | 7 | Physical Chemistry |
In organic chemistry, alkyl nitrites are a group of organic compounds based upon the molecular structure , where R represents an alkyl group. Formally they are alkyl esters of nitrous acid. They are distinct from nitro compounds ().
The first few members of the series are volatile liquids; methyl nitrite and ethyl nitr... | 0 | Organic Chemistry |
The modern non-stick pans were made using a coating of Teflon (polytetrafluoroethylene or PTFE). PTFE was invented serendipitously by Roy Plunkett in 1938, while working for a joint venture of the DuPont company. The substance was found to have several unique properties, including very good corrosion-resistance and the... | 7 | Physical Chemistry |
High levels of mixed-function oxidase activity have been studied for their activation effects in human colon carcinoma cell lines, to study the susceptibility to certain cancers. The research has been successful in mice but remains inconclusive in humans. | 1 | Biochemistry |
* An array or slide is a collection of features spatially arranged in a two dimensional grid, arranged in columns and rows.
* Block or subarray: a group of spots, typically made in one print round; several subarrays/ blocks form an array.
* Case/control: an experimental design paradigm especially suited to the two-colo... | 1 | Biochemistry |
Thermal rearrangements of aromatic hydrocarbons have been shown to be important in areas of chemical research and industry including fullerene synthesis, materials applications, and the formation of soot in combustion. Thermal rearrangements of aceanthrylene and acephenanthrylene can yield fluoranthene, an important sp... | 5 | Photochemistry |
Photoacoustic spectroscopy is the measurement of the effect of absorbed electromagnetic energy (particularly of light) on matter by means of acoustic detection. The discovery of the photoacoustic effect dates to 1880 when Alexander Graham Bell showed that thin discs emitted sound when exposed to a beam of sunlight that... | 7 | Physical Chemistry |
The grand potential or Landau potential or Landau free energy is a quantity used in statistical mechanics, especially for irreversible processes in open systems.
The grand potential is the characteristic state function for the grand canonical ensemble. | 7 | Physical Chemistry |
He has been involved in many editorial boards of scientific journals. He was member of the editorial board of the Journal of Applied Electrochemistry (1988-2010), [http://www.scielo.cl/scielo.php?script=sci_serial&pid=0717-9707&lng=es&nrm=iso Journal of the Chilean Chemical Society] (1984-2007) and Electrocatalysis (20... | 7 | Physical Chemistry |
An introduction to Landau theory can be found here.
Based on Ginzburg–Landau theory, the free energy of a ferroelectric material, in the absence of an electric field and applied stress may be written as a Taylor expansion in terms of the order parameter, P. If a sixth order expansion is used (i.e. 8th order and higher... | 7 | Physical Chemistry |
Nearly all cell membranes in animals, plants and fungi maintain a voltage difference between the exterior and interior of the cell, called the membrane potential. A typical voltage across an animal cell membrane is −70 mV. This means that the interior of the cell has a negative voltage relative to the exterior. In most... | 7 | Physical Chemistry |
PELP1 functions as a coactivator of several NRs and regulates genes involved in proliferation and cancer progression. PELP1 enhances transcription functions of ESR1, ESR2, AR, GR, E2F and STAT3. PELP1 participates in activation of ESR1 extra-nuclear actions by coupling ESR1 with Src kinase PI3K STAT3 ILK1 and mTO... | 1 | Biochemistry |
This book is a description of the various types of veins that can be found. There are 30 illustrations of different forms of these veins, forming the majority of Book III. Agricola also describes a compass to determine the direction of veins and mentions that some writers claim that veins lying in certain directions a... | 8 | Metallurgy |
A nitrate test is a chemical test used to determine the presence of nitrate ion in solution. Testing for the presence of nitrate via wet chemistry is generally difficult compared with testing for other anions, as almost all nitrates are soluble in water. In contrast, many common ions give insoluble salts, e.g. halides ... | 3 | Analytical Chemistry |
In 2000, with the help of plant breeders and the Organic Research Centre, the scientist Martin Wolfe crossed 20 varieties of wheat (selected for quality and yield) and crossed them to obtain 190 new crosses. These seeds were not further selected and planted, grown, harvested and reseeded together as a population.
Marti... | 1 | Biochemistry |
A DID is an ion detector which uses a high-voltage electric discharge to produce ions. The detector uses an electrical discharge in helium to
generate high energy UV photons and metastable helium which ionizes all compounds except helium. The ions produce an electric current, which is the signal output of... | 3 | Analytical Chemistry |
Attosecond pump-probe experiments with simple atoms is a fundamental tool to measure the time duration of an attosecond pulse and to explore several quantum proprieties of matter.
This kind of experiments can be easily described within strong field approximation by exploiting the results of Eq. , as discussed below.
A... | 7 | Physical Chemistry |
To measure the IMFP, one well known method is elastic-peak electron spectroscopy (EPES). This method measures the intensity of elastically backscattered electrons with a certain energy from a sample material in a certain direction. Applying a similar technique to materials whose IMFP is known, the measurements are comp... | 7 | Physical Chemistry |
*1972 Paul W. Gast
*1973 Robert M. Garrels
*1974 Hans E. Suess
*1975 Harold C. Urey
*1976 Hans P. Eugster
*1977 Samuel Epstein
*1978 Gerald J. Wasserburg
*1979 Harmon Craig
*1980 Clair C. Patterson
*1981 Robert N. Clayton
*1982 Konrad B. Krauskopf
*1983 Samuel S. Goldich
*1984 Alfred Nier
*1985 James B. Thompson Jr.
*1... | 9 | Geochemistry |
Until 2007, in the United States, Lugol's solution was unregulated and available over the counter as a general reagent, an antiseptic, a preservative, or as a medicament for human or veterinary application.
Since 1 August 2007, the DEA regulates all iodine solutions containing greater than 2.2% elemental iodine as a Li... | 3 | Analytical Chemistry |
A deficiency associated with lysosomal acid lipase deficiency, Wolman disease, and cholesteryl ester storage disease.
Chlorpromazine is an inhibitor of lysosomal lipase.
A genome wide survey suggests that lysosomal lipase A (located at chromosome 10q23.31) is associated with coronary artery disease in humans. | 1 | Biochemistry |
The Fenna–Matthews–Olson (FMO) complex is a water-soluble complex and was the first pigment-protein complex (PPC) to be structure analyzed by x-ray spectroscopy. It appears in green sulfur bacteria and mediates the excitation energy transfer from light-harvesting chlorosomes to the membrane-embedded bacterial reaction ... | 5 | Photochemistry |
Lowering photorespiration may not result in increased growth rates for plants. Photorespiration may be necessary for the assimilation of nitrate from soil. Thus, a lowering in photorespiration by genetic engineering or because of increasing atmospheric carbon dioxide may not benefit plants as has been proposed. Several... | 5 | Photochemistry |
Microcystins covalently bond to and inhibit protein phosphatases PP1 and PP2A and can thus cause pansteatitis. The ADDA residue is key to this functionality: greatly simplified synthetic analogues consisting of ADDA and one additional amino acid can show the same inhibiting function. | 2 | Environmental Chemistry |
The adapters that annealed successfully are extended and synthesized by a DNA polymerase to complete a double-stranded adapter containing complementary tags (Figure 1). | 1 | Biochemistry |
Electrodeionization (EDI) is a water treatment technology that utilizes DC power, ion exchange membranes, and ion exchange resin to deionize water. EDI is typically employed as a polishing treatment following reverse osmosis (RO), and is used in the production of ultrapure water. It differs from other RO polishing meth... | 7 | Physical Chemistry |
Hypothermia therapy for neonatal encephalopathy has been proven to improve outcomes for newborn infants affected by perinatal hypoxia-ischemia, hypoxic ischemic encephalopathy or birth asphyxia. A 2013 Cochrane review found that it is useful in full term babies with encephalopathy. Whole body or selective head cooling ... | 1 | Biochemistry |
Carbomethoxymethylenetriphenylphosphorane can be made via a multistep reaction using bromoacetic acid, dicyclohexylcarbodiimide, and triphenylphosphine. This makes a phosphonium salt, which is converted to the final product by sodium carbonate in water. | 0 | Organic Chemistry |
Imperfect inverted repeats can lead to mutations through intrastrand and interstrand switching. The antithrombin III gene's coding region is an example of an imperfect inverted repeat as shown in the figure on the right.
The stem-loop structure forms with a bump at the bottom because the G and T do not pair up. A stra... | 1 | Biochemistry |
The radial spoke is a multi-unit protein structure found in the axonemes of eukaryotic cilia and flagella. Although experiments have determined the importance of the radial spoke in the proper function of these organelles, its structure and mode of action remain poorly understood. | 1 | Biochemistry |
Rivers and submarine hydrothermal emanations supply 6.1 × 10 g SiO yr to the marine environment. Approximately two-thirds of this silica input is stored in continental margin and deep-sea deposits. Siliceous deep-sea sediments located beneath the Antarctic Convergence (convergence zone) host some 25% of the silica supp... | 1 | Biochemistry |
Vapor diffusion is the most commonly employed method of protein crystallization. In this method, droplets containing purified protein, buffer, and precipitant are allowed to equilibrate with a larger reservoir containing similar buffers and precipitants in higher concentrations. Initially, the droplet of protein soluti... | 3 | Analytical Chemistry |
Bi-metallic coins and medals have been issued for a long time. The Roman Empire issued special-occasion, large medallions with a center of bronze or copper and an outer ring of orichalcum, starting with the reign of Hadrian. Meanwhile, circulating bi-metallic coins are known from the 17th century. English farthings fro... | 8 | Metallurgy |
Bacteria become highly tolerant to antibiotics when nutrients are limited. Starvation contributes to antibiotic tolerance during infection, as nutrients become limited when they are sequestered by host defenses and consumed by proliferating bacteria. One of the most important causes of starvation induced tolerance in v... | 1 | Biochemistry |
In classical Lewis structures, molecular oxygen, O, is depicted as having a double bond between the two oxygen atoms. However, the molecular orbitals of O are actually more complex than Lewis structures seem to suggest. The highest occupied molecular orbital (HOMO) of O is a pair of degenerate antibonding π orbitals, ... | 5 | Photochemistry |
In human digestion, proteins in food are broken down into smaller peptide chains by digestive enzymes such as pepsin, trypsin, chymotrypsin, and elastase, and into amino acids by various enzymes such as carboxypeptidase, aminopeptidase, and dipeptidase. It is necessary to break down proteins into small peptides (tripep... | 1 | Biochemistry |
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