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Variations of the steroid 21-hydroxylase can be found in all vertebrates.
Cyp21 first emerged in chordates before the speciation between basal chordates and vertebrates. The sea lamprey, an early jawless fish species that originated over 500 million years ago, provides valuable insights into the evolution and emergence... | 1 | Biochemistry |
A neurochemical is a small organic molecule or peptide that participates in neural activity. The science of neurochemistry studies the functions of neurochemicals. | 1 | Biochemistry |
Liver of sulfur was once used to counteract poisoning with several metals, including arsenic, copper, lead, and antimony. A lump was dissolved in warm water and the patient was instructed to drink the solution three or four times over the course of an hour. At one time sulfurated potash was used to combat arthritis. ... | 7 | Physical Chemistry |
DNA has a negative charge and so will move to the positive electrode in an electric field. A gel is a molecular mesh, with holes roughly the same size as the diameter of the DNA string. When an electric field is applied, the DNA will begin to move through the gel, at a speed roughly inversely proportional to the length... | 1 | Biochemistry |
The action potential in a normal skeletal muscle cell is similar to the action potential in neurons. Action potentials result from the depolarization of the cell membrane (the sarcolemma), which opens voltage-sensitive sodium channels; these become inactivated and the membrane is repolarized through the outward current... | 7 | Physical Chemistry |
Thyroid hormone increases the number of beta-adrenergic receptors available for epinephrine at the latters target cell, thereby increasing epinephrines effect on that cell. Specially in cardiac cell. Without the thyroid hormone, epinephrine would have only a weak effect.
Cortisol is required for the response of vascula... | 1 | Biochemistry |
As a student, Eötvös started to research surface tension and developed a new method for its determination. The Eötvös rule was first found phenomenologically and published in 1886. In 1893 William Ramsay and Shields showed an improved version considering that the line normally passes the temperature axis 6 K before the... | 7 | Physical Chemistry |
MCT2 transporters within the peroxisome function to transport pyruvate into the peroxisome where it is reduced by peroxisomal LDH (pLDH) to lactate. In turn, NADH is converted to NAD+, regenerating this necessary component for subsequent β-oxidation. Lactate is then shuttled out of the peroxisome via MCT2, where it is... | 1 | Biochemistry |
Two drops of iron(III) chloride are added to a test tube with distilled water. After mixing, it is divided into two parts. Add one millilitre of gastric juice in one test tube and the same volume of distilled water in the other test tube, which is acting as a control. The test tube with the gastric juice turns yellow i... | 3 | Analytical Chemistry |
This type of equipment has an eccentric drive or weights that causes the shaker to travel in an orbital path. The material rolls over the screen and falls with the induction of gravity and directional shifts. Rubber balls and trays provide an additional mechanical means to cause the material to fall through. The bal... | 8 | Metallurgy |
FS 49 C2 acts similarly to an inert gas. It absorbs the heat produced from the combustion process. This mechanism is consistent with the observation that the fire heat release rate does not decrease until sufficient gas is released.
The difference from inert gases and FS 49 C2 is that it takes less gas to suppress a fi... | 2 | Environmental Chemistry |
* 2012 – Pearson Education RACI Centenary of Federation Chemistry Educator of the Year Award
* 2011 – Vice-Chancellor's Award for Outstanding Teaching
* 2011 – Australian Learning and Teaching Council Citation for Teaching Excellence
* 2010 – Vice-Chancellor's Award for Support of the Student Experience
* 2008 – NSW an... | 0 | Organic Chemistry |
There were various iron-making ventures during the 19th Century, and steel was made but only on a very small scale.
The first commercial scale production of steel in Australia was by William Sandford Limited at the Eskbank Ironworks at Lithgow, New South Wales, in 1901. The plant became Australias first integrated iro... | 8 | Metallurgy |
The starting material for this route is a β-(Δ-cyclopentenyl)-ethane derivative with a good leaving group on the terminal carbon of the ethane group. Electron density from the π bond of the alkene moiety is donated into the σ* anti-bond between the terminal carbon and the leaving group (see Figure 8c).
For example, the... | 7 | Physical Chemistry |
Alpine lakes located in the Central Pyrenees region of northeast Spain are unaffected by anthropogenic factors making these oligotrophic lakes ideal indicators for sediment input and environmental change. Dissolved organic matter and nutrients from dust transport can aid bacteria with growth and production in low nutri... | 7 | Physical Chemistry |
Iron can also enter cells via CD44 in complexes bound to hyaluronic acid during epithelial–mesenchymal transition (EMT). In this process, epithelial cells transform into mesenchymal cells with detachment from the basement membrane, to which they’re normally anchored, paving the way for the newly differentiated motile m... | 1 | Biochemistry |
The simplest mathematical model to explain the Vroman Effect is the Langmuir model using the Langmuir isotherm. More complex models include the Fruendlich isotherm and other modifications to the Langmuir model. This model explains the kinetics between reversible adsorption and desorption, assuming the adsorbate behaves... | 7 | Physical Chemistry |
The receptor-based approach is used in exposure science. It starts by looking at different contaminants and concentrations that reach people. An exposure analyst can use direct or indirect measurements to determine if a person has been in contact with a specific contaminant or has been exposed to a specific risk (e.g. ... | 2 | Environmental Chemistry |
In order to combat the potential global warming effects of F-gases, and as part of the EU's Kyoto protocol commitments, in 2006 the European Union passed two pieces of legislation controlling their use: the [http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2006:161:0001:0011:EN:PDF F-gas Regulation (EC) No 84... | 2 | Environmental Chemistry |
Gene therapy encapsulates many forms of adding different nucleic acids to a cell. Gene augmentation adds a new protein coding gene to a cell. One form of gene augmentiation is gene replacement therapy, a treatment for monogenic recessive disorders where a single gene is not functional an additional functional gene is a... | 1 | Biochemistry |
* Antirrhinin (cyanidin-3-rutinoside or 3-C-R), found in black raspberry
* Cyanidin-3-xylosylrutinoside, found in black raspberry
* Cyanidin-3,4′-di-O-β-glucopyranoside, found in red onion
* Cyanidin-4′-O-β-glucoside, found in red onion
* Chrysanthemin (cyanidin-3-O-glucoside), found in blackcurrant pomace
* Ideain (cy... | 3 | Analytical Chemistry |
When sequencing RNA other than mRNA, the library preparation is modified. The cellular RNA is selected based on the desired size range. For small RNA targets, such as miRNA, the RNA is isolated through size selection. This can be performed with a size exclusion gel, through size selection magnetic beads, or with a c... | 1 | Biochemistry |
Post-treatment disinfection provides secondary protection against compromised membranes and downstream problems. Disinfection by means of ultraviolet (UV) lamps (sometimes called germicidal or bactericidal) may be employed to sterilize pathogens that evade the RO process. Chlorination or chloramination (chlorine and am... | 3 | Analytical Chemistry |
Selection favors different traits in captive populations than it does in wild populations, so this may result in adaptations that are beneficial in captivity but are deleterious in the wild. This reduces the success of re-introductions, so it is important to manage captive populations in order to reduce adaptations to ... | 1 | Biochemistry |
Alternatives for normally occupied areas include (PFC-410 or CEA-410), CF (PFC-218 or CEA-308), HCFC Blend A (NAF S-III), HFC-23 (FE 13), HFC-227ea (FM 200), IG-01 (argon), IG-55 (argonite), HFC-125, or HFC-134a. For normally unoccupied areas, the alternatives include carbon dioxide, powdered Aerosol C, CFI, HCFC-22, H... | 2 | Environmental Chemistry |
Impurities usually enter the solder reservoir by dissolving the metals present in the assemblies being soldered. Dissolving of process equipment is not common as the materials are usually chosen to be insoluble in solder.
* Aluminium – little solubility, causes sluggishness of solder and dull gritty appearance due to f... | 8 | Metallurgy |
Ethers feature bent linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp.
Oxygen is more electroneg... | 0 | Organic Chemistry |
A breakthrough curve in adsorption is the course of the effluent adsorptive concentration at the outlet of a fixed bed adsorber. Breakthrough curves are important for adsorptive separation technologies and for the characterization of porous materials. | 7 | Physical Chemistry |
Carbon sequestration is part of the natural carbon cycle by which carbon is exchanged among the biosphere, pedosphere, geosphere, hydrosphere, and atmosphere of Earth.
Carbon dioxide is naturally captured from the atmosphere through biological, chemical or physical processes, and stored in long-term reservoirs.
Forests... | 5 | Photochemistry |
The magnetostriction effect describes a property of ferromagnetic materials which causes them to change their shape when subjected to a magnetic field. Joule first reported observing the change in the length of ferromagnetic rods in 1842. | 7 | Physical Chemistry |
Bacteria can use several different electron donors. When organic matter is the electron source, the donor may be NADH or succinate, in which case electrons enter the electron transport chain via NADH dehydrogenase (similar to Complex I in mitochondria) or succinate dehydrogenase (similar to Complex II). Other dehydroge... | 1 | Biochemistry |
Nagai continued his studies at Tokyo Imperial University and became the first doctor of pharmacy in Japan. He was sent under government sponsorship to Prussia in 1871 to study at the University of Berlin. He was the only civilian in a group of military students sent to study in Great Britain and France, and he traveled... | 0 | Organic Chemistry |
Thiophosphates (or phosphorothioates, PS) are chemical compounds and anions with the general chemical formula (x = 0, 1, 2, or 3) and related derivatives where organic groups are attached to one or more O or S. Thiophosphates feature tetrahedral phosphorus(V) centers. | 0 | Organic Chemistry |
In the absence of an effective enantiomeric environment (precursor, chiral catalyst, or kinetic resolution), separation of a racemic mixture into its enantiomeric components is impossible, although certain racemic mixtures spontaneously crystallize in the form of a racemic conglomerate, in which crystals of the enantio... | 4 | Stereochemistry |
In 2006 Goossen et al. proposed a reaction to synthesize biaryl compounds via catalytic decarboxylative cross coupling.
The mechanism involves two overlapping cycles, one using a copper halide and the other using palladium. The decarboxylation step occurs between the substituted benzoic acid and copper halide to form t... | 0 | Organic Chemistry |
To overcome problems associated with oligonucleotide quality several elaborate strategies have been developed, employing either separately prepared fishing oligonucleotides, mismatch binding enzymes of the mutS family or specific endonucleases from bacteria or phages. Nevertheless, all these strategies increase time an... | 1 | Biochemistry |
Once the function of the mutated protein has been determined it is possible to sequence/purify/clone the regions flanking the insertion by the following methods: | 1 | Biochemistry |
Tailings do not have to be stored in ponds or sent as slurries into oceans, rivers or streams. There is a growing use of the practice of dewatering tailings using vacuum or pressure filters so the tailings can then be stacked. This saves water which potentially reduces the impacts on the environment in terms of a reduc... | 8 | Metallurgy |
Although as a general rule, dietary supplement labeling and marketing are not allowed to make disease prevention or treatment claims, the FDA has for some foods and dietary supplements reviewed the science, concluded that there is significant scientific agreement, and published specifically worded allowed health claims... | 1 | Biochemistry |
The spectral absorption is equal to the emissivity ; this relation is known as Kirchhoff's law of thermal radiation. An object is called a black body if this holds for all frequencies, and the following formula applies:
If objects appear white (reflective in the visual spectrum), they are not necessarily equally reflec... | 7 | Physical Chemistry |
C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system such as sepsis, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythemotosis, psoriasis. The inhibitor of C5a that can block its effects w... | 1 | Biochemistry |
The Toda oscillator is a dynamical system of any origin, which can be described with dependent coordinate and independent coordinate , characterized in that the evolution along independent coordinate can be approximated with equation
where
, and prime denotes the derivative. | 7 | Physical Chemistry |
Using the definition above for and , the first and second derivatives can be expressed in terms of the Faddeeva function as
and
respectively.
Often, one or multiple Voigt profiles and/or their respective derivatives need to be fitted to a measured signal by means of non-linear least squares, e.g., in spectroscopy. The... | 7 | Physical Chemistry |
The 5′ UTR begins at the transcription start site and ends one nucleotide (nt) before the initiation sequence (usually AUG) of the coding region. In prokaryotes, the length of the 5′ UTR tends to be 3–10 nucleotides long, while in eukaryotes it tends to be anywhere from 100 to several thousand nucleotides long. For exa... | 1 | Biochemistry |
Miray Bekbölet is a Turkish environmental chemist researching oxidation techniques, photocatalytic and photolytic reactions, adsorption/bio-oxidation processes in aquatic systems, and drinking water quality. She is a professor of environmental chemistry at the Boğaziçi University Institute of Environmental Sciences. | 5 | Photochemistry |
It has been used to produce smoke screens since it produces a heavy, white smoke that has little tendency to rise. "Tickle" was the standard means of producing on-set smoke effects for motion pictures, before being phased out in the 1980s due to concerns about hydrated HCl's effects on the respiratory system. | 0 | Organic Chemistry |
Nitric acid is the inorganic compound with the formula . It is a highly corrosive mineral acid. The compound is colorless, but samples tend to acquire a yellow cast over time due to decomposition into oxides of nitrogen. Most commercially available nitric acid has a concentration of 68% in water. When the solution cont... | 3 | Analytical Chemistry |
Non-classical ions differ from traditional cations in their electronic structure: though chemical bonds are typically depicted as the sharing of electrons between two atoms, stable non-classical ions can contain three or more atoms that share a single pair of electrons. In 1939, Thomas Nevell and others attempted to el... | 7 | Physical Chemistry |
* King Chandra and the Mehrauli Pillar, M.C. Joshi, S.K. Gupta and Shankar Goyal, Eds., Kusumanjali Publications, Meerut, 1989.
* The Rustless Wonder – A Study of the Iron Pillar at Delhi, T.R. Anantharaman, Vigyan Prasar New Delhi, 1996.
* Delhi Iron Pillar: New Insights. R. Balasubramaniam, Aryan Books International,... | 8 | Metallurgy |
Transferrins are glycoproteins that are often found in biological fluids of vertebrates. When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell, e.g., erythroid precursors in the bone marrow, it binds to it and is transported into the cell in a vesicle by receptor-mediate... | 1 | Biochemistry |
Ethylene binds to it specific transmembrane receptor present on the cell membrane of endoplasmic reticulum. There are different ethylene receptor isoforms. Five isoforms are known in Arabidopsis thaliana which are named ethylene response/receptor 1 (ETR1), ethylene response sensor 1 (ERS1), ETR2, ERS2, and ethylene ins... | 1 | Biochemistry |
Surface bodies of water provide environments able to dry out and be rewetted. Continued wet-dry cycles allow the concentration of prebiotic compounds and condensation reactions to polymerise macromolecules. Moreover, lake and ponds on land allow for detrital input from the weathering of continental rocks which contain ... | 9 | Geochemistry |
In terms of flowering time in long day conditions, all mutants made the observed flowering late, with PRR7 significantly more late in comparison to the other mutants. All double mutants with PRR7 saw much later flowering time than the PRR5/PRR9 mutant. | 1 | Biochemistry |
The first study reporting molecular delivery using ultrasound was a 1987 in vitro study attempting to transfer plasmid DNA to cultured mouse fibroblast cells using sonoporation. This successful plasmid DNA transfection conferring G418 antibiotic resistance ultimately led to further in vitro studies that hinted at the p... | 1 | Biochemistry |
The Thyrotroph Thyroid Hormone Sensitivity Index (abbreviated TTSI, also referred to as Thyrotroph T4 Resistance Index or TT4RI) is a calculated structure parameter of thyroid homeostasis. It was originally developed to deliver a method for fast screening for resistance to thyroid hormone. Today it is also used to get ... | 1 | Biochemistry |
The Governing Board of the Eastern Analytical Symposium presents awards each year for outstanding contributions and achievements in general analytical chemistry and in five specific areas of analysis. The award inscriptions read, "In Recognition of Outstanding Achievements in the Field of -----".
*Analytical Chemistry
... | 7 | Physical Chemistry |
Magnetation is the processing of iron ore tailings, the waste product of iron ore mines, to recover hematite. Crushed mine tailings are mixed with water to create a slurry; the slurry is then pumped through magnetic separation chambers to extract hematite. Commercial interest in this process stems from the possibility... | 8 | Metallurgy |
Experimentation with respiratory oxidase inhibitors (for instance, cyanide) on unicellular algae has revealed interactive pathways to be present between chloroplasts and mitochondria. Metabolic pathways responsible for photosynthesis are present in chloroplasts, whereas respiratory metabolic pathways are present in mit... | 1 | Biochemistry |
One of the drawbacks of using a separating funnel is emulsions can form easily, and can take a long time to separate once formed. They are often formed while liquids are being mixed in the separating funnel. This can occur when small droplets are suspended in an aqueous solution. If an emulsion is formed, one technique... | 3 | Analytical Chemistry |
Certain kinds of IVF have been shown to lead to distortions in the sex ratio at birth. Intracytoplasmic sperm injection (ICSI), which was first applied in 1991, leads to slightly more female births (51.3% female). Blastocyst transfer, which was first applied in 1984, leads to significantly more male births (56.1% male)... | 1 | Biochemistry |
It monitors background radiation in the UK. Workers exposed to radiation include workers in dental radiography and nuclear power stations; exposure to radiation for workers in the UK must be ALARP. It offers 3-day training courses around twice a month, at a national level, for workers exposed to radiation.
It produces ... | 2 | Environmental Chemistry |
A blotting matrix, in molecular biology and genetics, is the substrate onto which macromolecules, such as proteins, are transferred in a blot method. The matrices are generally chemically modified paper filters or microporous membrane filters. In a dot blot, macromolecules are applied directly to the matrix. Macromolec... | 1 | Biochemistry |
Mixed liquor suspended solids (MLSS) is the concentration of suspended solids, in an aeration tank during the activated sludge process, which occurs during the treatment of waste water. The units MLSS is primarily measured in milligram per litre (mg/L), but for activated sludge its mostly measured in gram per litre [g/... | 3 | Analytical Chemistry |
The term "virokine" was coined by National Institutes of Health virologist Bernard Moss. The early 1990s saw several reports of virally encoded proteins with sequence homology to immune proteins, followed by reports of the cowpox and vaccinia viruses directly interfering with key immune regulator IL1B. The first identi... | 1 | Biochemistry |
This family of clusters includes the nido cages . Relatively little work has been devoted to these compounds. Pentaborane[9] reacts with acetylene to give nido-1,2-. Upon treatment with sodium hydride, latter forms the salt [1,2-. | 7 | Physical Chemistry |
pK values of amino acid side chains play an important role in defining the pH-dependent characteristics of a protein. The pH-dependence of the activity displayed by enzymes and the pH-dependence of protein stability, for example, are properties that are determined by the pK values of amino acid side chains.
The pK valu... | 7 | Physical Chemistry |
Molecular Physics is a peer-reviewed scientific journal covering research on the interface between chemistry and physics, in particular chemical physics and physical chemistry. It covers both theoretical and experimental molecular science, including electronic structure, molecular dynamics, spectroscopy, reaction kinet... | 7 | Physical Chemistry |
Later in the 20th century several British pathologists, Mikey Rochman, Francis Camps, Sydney Smith and Keith Simpson pioneered new forensic science methods. Alec Jeffreys pioneered the use of DNA profiling in forensic science in 1984. He realized the scope of DNA fingerprinting, which uses variations in the genetic cod... | 3 | Analytical Chemistry |
The NMDA receptor (NMDAR) does not, in resting or near-resting membrane potential conditions, contribute significant current to the EPSP. Following the presynaptic release of the glutamate that binds to and opens the AMPAR, the NMDAR also binds this glutamate and opens. However, current does not flow through the NMDAR ... | 1 | Biochemistry |
Perilipin expression is elevated in obese animals and humans. Polymorphisms in the human perilipin (PLIN) gene have been associated with variance in body-weight regulation and may be a genetic influence on obesity risk in humans.
This protein can be modified by O-linked acetylglucosamine (O-GlNac) moieties and the enzy... | 1 | Biochemistry |
In the medical field, experiments are done to test for the uses of cell-cell fusogens in axonal nerve repairs and to determine their usefulness with other nerve cells. The current method for nerve repair is suturing the cut ends of nerves. This has a long recovery process, with a low functionality rate for the repaired... | 1 | Biochemistry |
For a system undergoing a reversible reaction described by the general chemical equation
a thermodynamic equilibrium constant, denoted by , is defined to be the value of the reaction quotient Q when forward and reverse reactions occur at the same rate. At chemical equilibrium, the chemical composition of the mixture do... | 7 | Physical Chemistry |
In chemistry, a Zintl phase is a product of a reaction between a group 1 (alkali metal) or group 2 (alkaline earth metal) and main group metal or metalloid (from groups 13, 14, 15, or 16). It is characterized by intermediate metallic/ionic bonding. Zintl phases are a subgroup of brittle, high-melting intermetallic comp... | 7 | Physical Chemistry |
A study of non-medical use potential of eszopiclone found that in persons with a known history of non-medical benzodiazepine use, eszopiclone at doses of 6 and 12 mg produced effects similar to those of diazepam 20 mg. The study found that at these doses which are two or more times greater than the maximum recommended ... | 4 | Stereochemistry |
Transvection is an epigenetic phenomenon that results from an interaction between an allele on one chromosome and the corresponding allele on the homologous chromosome. Transvection can lead to either gene activation or repression. It can also occur between nonallelic regions of the genome as well as regions of the gen... | 1 | Biochemistry |
In 1943, he defended his Ph.D. thesis on “Obtaining Hexamethylenetetramine (urotropine) from Natural Gas”. In 1945, the Synthesis of Additives Laboratory was organized in Azerbaijan Scientific-Research Institute of Oil-Processing. Guliyev headed this laboratory. As a result of experiments by him and his team, lubricati... | 0 | Organic Chemistry |
Ethyltolune describes organic compounds with the formula . Three isomers exist: 1,2- 1,3-, and 1,4-. All are colorless liquids, immiscible in water, with similar boiling points. They are classified are aromatic hydrocarbons. The ring bears two substituents: a methyl group and an ethyl group. | 0 | Organic Chemistry |
Static light scattering measures the product of weight-averaged molar mass and concentration of macromolecules in solution. Given a fixed total concentration of one or more species over the measurement time, the scattering signal is a direct measure of the weight-averaged molar mass of the solution, which will vary as ... | 1 | Biochemistry |
TEs are mutagens and due to the contribution to the formation of new cis-regulatory DNA elements that are connected to many transcription factors that are found in living cells; TEs can undergo many evolutionary mutations and alterations. These are often the causes of genetic disease, and gives the potential lethal eff... | 1 | Biochemistry |
Plants respond and adapt to environmental factors, such as light and mechanical stress from wind. Leaves need to support their own mass and align themselves in such a way as to optimize their exposure to the sun, generally more or less horizontally. However, horizontal alignment maximizes exposure to bending forces and... | 5 | Photochemistry |
Transcriptomics has been characterised by the development of new techniques which have redefined what is possible every decade or so and rendered previous technologies obsolete. The first attempt at capturing a partial human transcriptome was published in 1991 and reported 609 mRNA sequences from the human brain. In 20... | 1 | Biochemistry |
Alfred G. Gilman and Martin Rodbell received the 1994 Nobel Prize in Medicine and Physiology for the discovery of the G Protein System. | 1 | Biochemistry |
The antenna complex is composed of molecules of chlorophyll and carotenoids mounted on two proteins. These pigment molecules transmit the resonance energy from photons when they become photoexcited. Antenna molecules can absorb all wavelengths of light within the visible spectrum. The number of these pigment molecules ... | 5 | Photochemistry |
After the successful operation of the BBOC at BRM, MIM Holdings Limited (“MIM”) decided to license the technology to other smelter and refinery operators. Early adopters included Hindustan Zinc Limited, which by 1995 had two 1 t BBOC plants operating in India, and ASARCO Inc., which was operating a 3 t BBOC furnace at ... | 8 | Metallurgy |
When a synonymous or silent mutation occurs, the change is often assumed to be neutral, meaning that it does not affect the fitness of the individual carrying the new gene to survive and reproduce.
Synonymous changes may not be neutral because certain codons are translated more efficiently (faster and/or more accuratel... | 1 | Biochemistry |
PKR (encoded in humans by the gene EIF2AK2) activation is mainly dependent on the presence of double-stranded RNA during a viral infection. dsRNA causes PKR to form dimers, resulting in autophosphorylation and activation. Once activated, PKR will phosphorylate eIF2α which causes a cascade of events that result in viral... | 1 | Biochemistry |
A point C on the screw axis satisfies the equation:
Solve this equation for C using Cayley's formula for a rotation matrix
where [B] is the skew-symmetric matrix constructed from Rodrigues' vector
such that
Use this form of the rotation A to obtain
which becomes
This equation can be solved for C on the screw axis P(t) ... | 3 | Analytical Chemistry |
A particularly interesting property of many catenanes is the ability of the rings to rotate with respect to one another. This motion can often be detected and measured by NMR spectroscopy, among other methods. When molecular recognition motifs exist in the finished catenane (usually those that were used to synthesize t... | 6 | Supramolecular Chemistry |
Millesimal fineness is a system of denoting the purity of platinum, gold and silver alloys by parts per thousand of pure metal by mass in the alloy. For example, an alloy containing 75% gold is denoted as "750". Many European countries use decimal hallmark stamps (i.e., "585", "750", etc.) rather than "14 k", "18 k", e... | 8 | Metallurgy |
RNF123 was found to be an interacting protein of FAM227B through Affinity Capture – MS. RAB3A was found to be an interacting protein of FAM227B through tandem affinity purification. | 1 | Biochemistry |
The hyperbolic response between photosynthesis and irradiance, depicted by the PI curve, is important for assessing phytoplankton population dynamics, which influence many aspects of the marine environment. | 5 | Photochemistry |
As describes, the vertices of the Laves graph can be defined by selecting one out of every eight points in the three-dimensional integer lattice, and forming their nearest neighbor graph. Specifically, one chooses the points
and all the other points formed by adding multiples of four to these coordinates. The edges of... | 3 | Analytical Chemistry |
Cocaine is a monoamine transporter blocker and, thus, an indirect agonist of dopamine receptors. Cocaine binds the dopamine transporter (DAT), blocking the protein's ability to uptake dopamine from the synaptic cleft and also blocking DAT from terminating dopamine signaling. Blockage of DAT increases the extracellular ... | 1 | Biochemistry |
BSi dissolution is controlled by:
* Thermodynamics of solubility: Temperature (0 to 25 °C - 50x increase).
* Sinking rate: Food web structure—grazers, fecal pellets, discarded feeding structures, Aggregation - rapid transport.
* Bacterial degradation of organic matrix (Bidle and Azam, 1999). | 1 | Biochemistry |
SELDI technology was developed by T. William Hutchens and Tai-Tung Yip at Baylor College of Medicine in 1993. Hutchens and Yip attached single-stranded DNA to agarose beads and used the beads to capture lactoferrin, an iron-binding glycoprotein, from preterm infant urine. The beads were incubated in the sample and then... | 1 | Biochemistry |
Another application for duplex sequencing is in the detection of DNA/RNA copy numbers by estimating the relative frequency of variants. A method for counting PCR template molecules with application to next-generation sequencing is an example. | 1 | Biochemistry |
A variety of reasons for a Phase I study to be performed exist, the most common being:
* Purchase of real property by a person or entity not previously on title.
* Contemplation by a new lender to provide a loan on the subject real estate.
* Partnership buyout or principal redistribution of ownership.
* Application to ... | 2 | Environmental Chemistry |
Isotopic labeling (or isotopic labelling) is a technique used to track the passage of an isotope (an atom with a detectable variation in neutron count) through chemical reaction, metabolic pathway, or a biological cell. The reactant is labeled by replacing one or more specific atoms with their isotopes. The reactant is... | 7 | Physical Chemistry |
Thymidine diphosphate glucose (often abbreviated dTDP-glucose or TDP-glucose) is a nucleotide-linked sugar consisting of deoxythymidine diphosphate linked to glucose. It is the starting compound for the syntheses of many deoxysugars. | 1 | Biochemistry |
Recently, functional experiments have revealed many novel functional roles of RNA modifications. Most of the RNA modifications are found on transfer-RNA and ribosomal-RNA, but also eukaryotic mRNA has been shown to be modified with multiple different modifications. 17 naturally occurring modifications on mRNA have been... | 1 | Biochemistry |
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