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The [https://cran.r-project.org/web/packages/caroline/index.html caroline CRAN R package] contains the only known implementation of an RA plot. However, the meta-transcriptomics [http://bioconductor.org/packages/devel/bioc/html/manta.html "manta" R package] provides a wrapper around this RA plot implementation and is ...
1
Gene expression + Signal Transduction
Nod factors structurally are lipochitooligosaccharides (LCOs) that consist of an N-acetyl--glucosamine chain linked through β-1,4 linkage with a fatty acid of variable identity attached to a non reducing nitrogen in the backbone with various functional group substitutions at the terminal or non-terminal residues. Nod f...
1
Gene expression + Signal Transduction
This gene encodes a member of the tyrosine kinase and, to be more specific, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type ...
1
Gene expression + Signal Transduction
DBT has been shown to physically interact with PER in vitro and in vivo, and to create a stable complex with PER throughout the circadian cycle. PER that has been phosphorylated by DBT is recognized by the Slimb protein. Slimb is a component of the Skp1/Cullin/F-box protein (SCF) ubiquitin ligase complex, which marks p...
1
Gene expression + Signal Transduction
The slip-line theory was co-developed by Hilda Geiringer in the early 1930s. She developed the Geiringer equations, which simplify the process of calculating the deformation.
0
Metallurgy
SH2 domains contain about 100 amino acid residues and exhibit a central antiparallel β-sheet centered between two α-helices. Binding to phosphotyrosine-containing peptides involves a strictly-conserved Arg residue that pairs with the negatively-charged phosphate on the phosphotyrosine, and a surrounding pocket that r...
1
Gene expression + Signal Transduction
While disposal into exhausted open pits is generally a straightforward operation, disposal into underground voids is more complex. A common modern approach is to mix a certain quantity of tailings with waste aggregate and cement, creating a product that can be used to backfill underground voids and stopes. A common ter...
0
Metallurgy
Anti-sigma factors are small proteins that bind to sigma factors and inhibit transcriptional activity in regulating prokaryote gene expression. Anti-sigma factors have both a sigma-binding domain and a sensory/signaling domain; this allows them to respond to signals inside and outside the cell. Anti-sigma factors have ...
1
Gene expression + Signal Transduction
Axe-monies (Spanish: Tajaderos) refer to bronze artifacts found in both western Mesoamerica and the northern Andes. Based on ethnohistorical, archaeological, chemical, and metallurgical analyses, the scholars Hosler, Lechtman and Holm have argued for their use in both regions (which are separated by thousands of miles)...
0
Metallurgy
Impurities usually enter the solder reservoir by dissolving the metals present in the assemblies being soldered. Dissolving of process equipment is not common as the materials are usually chosen to be insoluble in solder. * Aluminium – little solubility, causes sluggishness of solder and dull gritty appearance due to f...
0
Metallurgy
Woodchuck Hepatitis Virus (WHV) Posttranscriptional Regulatory Element (WPRE) is a DNA sequence that, when transcribed, creates a tertiary structure enhancing expression. The sequence is commonly used in molecular biology to increase expression of genes delivered by viral vectors. WPRE is a tripartite regulatory elemen...
1
Gene expression + Signal Transduction
Mechanical alloying is akin to metal powder processing, where metals may be mixed to produce superalloys. Mechanical alloying occurs in three steps. First, the alloy materials are combined in a ball mill and ground to a fine powder. A hot isostatic pressing (HIP) process is then applied to simultaneously compress and s...
0
Metallurgy
Numerous gold artifacts recovered in the Philippines are believed to have ceremonial purposes. Some of these figures indicate the Hindu and Buddhist influence which came to the Philippines through regional trade in maritime southeast asia, while others reflect nature-based religious beliefs. A notable artifact reflect...
0
Metallurgy
Finally, biological and bio-hybrid drug carriers have shown potential for chemotactic applications. In general, these systems are inspired by microorganisms or cells to help design drug delivery systems that mimic their surface, shape, texture, and movement. One phenomenon that has become increasingly popular in improv...
1
Gene expression + Signal Transduction
A metallurgical assay is a compositional analysis of an ore, metal, or alloy, usually performed in order to test for purity or quality. Some assay methods are suitable for raw materials; others are more appropriate for finished goods. Raw precious metals (bullion) are assayed by an assay office. Silver is assayed by ti...
0
Metallurgy
Testing and/or inspection are typically included in component manufacturing lines to verify the product meets some set of standards to ensure the desired performance in the field. Improper testing or inspection would circumvent these quality checks and could allow a part with a defect that would normally disqualify the...
0
Metallurgy
Structurally, rusticles contain channels which allow water to flow through, and they seem to build up in a ring structure similar to the growth rings of a tree. They are very delicate and can easily disintegrate into fine powder on even the slightest touch.
0
Metallurgy
It was the second stop codon mutation to be discovered. Reminiscent of the usual yellow-orange-brown color associated with amber, this second stop codon was given the name of "ochre", an orange-reddish-brown mineral pigment. Ochre mutant viruses had a property similar to amber mutants in that they recovered infectious ...
1
Gene expression + Signal Transduction
*The lac operon consists of 3 structural genes, and a promoter, a terminator, regulator, and an operator. The three structural genes are: lacZ, lacY, and lacA. **lacZ encodes β-galactosidase (LacZ), an intracellular enzyme that cleaves the disaccharide lactose into glucose and galactose. ** lacY encodes Beta-galactosi...
1
Gene expression + Signal Transduction
DIC has largely replaced the older oblique illumination (OI) technique, which was available on reflected light microscopes prior to about 1975. In OI, the vertical illuminator is offset from perpendicular, producing shading effects that reveal height differences. This procedure reduces resolution and yields uneven illu...
0
Metallurgy
Rust is a commonly used metaphor for slow decay due to neglect, since it gradually converts robust iron and steel metal into a soft crumbling powder. A wide section of the industrialized American Midwest and American Northeast, once dominated by steel foundries, the automotive industry, and other manufacturers, has exp...
0
Metallurgy
A metallurgical method employed in the purification of copper which contains copper oxide as an impurity and also in the purification of tin which contains tin oxide (stannic oxide or "SnO") as an impurity. The impure metal, usually in the form of molten blister copper, is placed in an anode furnace for two stages of r...
0
Metallurgy
Depending on the size of the alloying element, a substitutional solid solution or an interstitial solid solution can form. In both cases, atoms are visualised as rigid spheres where the overall crystal structure is essentially unchanged. The rationale of crystal geometry to atom solubility prediction is summarized in t...
0
Metallurgy
NF-Y is a heterotrimeric complex composed of NF-YA, NF-YB, and NF-YC subunits. The key structural feature of the NF-Y/DNA complex is the minor-groove interaction of its DNA binding domain-containing subunit NF-YA, which induces an ~80° bend in the DNA. NF-YB and NF-YC interact with DNA through non-specific histone-fold...
1
Gene expression + Signal Transduction
The evaluated parameters are: * time to specimen failure (e.g., breakage, or from other "failure" criteria) * ductility (by elongation to fracture or the reduction of the area) * ultimate tensile strength (from the maximum load) * area under the elongation - load curve (which represents the fracture energy) * percent ...
0
Metallurgy
STAT4 binds to hundreds of sites in the genome, among others to the promoters of genes for cytokines (IFN-γ, TNF), receptors (IL18R1, IL12rβ2, IL18RAP), and signaling factors (MYD88).
1
Gene expression + Signal Transduction
Proteins are translated by reading tri-nucleotides on the mRNA strand, also known as codons, from one end of the mRNA to the other (from the 5 to the 3 end) starting with the amino acid methionine as the start (initiation) codon AUG. Each codon is translated into a single amino acid. The code itself is considered dege...
1
Gene expression + Signal Transduction
Downs' process is an electrochemical method for the commercial preparation of metallic sodium, in which molten NaCl is electrolyzed in a special apparatus called the Downs cell. The Downs cell was invented in 1923 (patented: 1924) by the American chemist James Cloyd Downs (1885–1957).
0
Metallurgy
In order to see whether p53 re-expression in cancer cells (that have lost p53 expression) has the suppressive effect on the promoter of the survivin gene, a luciferase reporter construct was made. The isolated survivin promoter was placed upstream of the luciferase reporter gene. In a luciferase reporter assay, if the ...
1
Gene expression + Signal Transduction
Some hydrogen sulfide gas diffuses into the headspace environment above the wastewater. Moisture evaporated from warm sewage may condense on unsubmerged walls of sewers, and is likely to hang in partially formed droplets from the horizontal crown of the sewer. As a portion of the hydrogen sulfide gas and oxygen gas f...
0
Metallurgy
Coding regions are composed of codons, which are decoded and translated into proteins by the ribosome; in eukaryotes usually into one and in prokaryotes usually into several. Coding regions begin with the start codon and end with a stop codon. In general, the start codon is an AUG triplet and the stop codon is UAG ("am...
1
Gene expression + Signal Transduction
RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized by RNA polymerase III), a type of RNA that accounts for over 50% of the total RNA synthesized in a cell.
1
Gene expression + Signal Transduction
Several genetic diseases may be the result of splice site mutations. For example, mutations that cause the incorrect splicing of β-globin mRNA are responsible of some cases of β-thalassemia. Another Example is TTP (thrombotic thrombocytopenic purpura). TTP is caused by deficiency of ADAMTS-13. A splice site mutation of...
1
Gene expression + Signal Transduction
Currently the most important application is due to the special magnetic properties of some ferromagnetic metallic glasses. The low magnetization loss is used in high efficiency transformers (amorphous metal transformer) at line frequency and some higher frequency transformers. Amorphous steel is a very brittle material...
0
Metallurgy
Hellenistic and Graeco-Roman forms are more conventional, and the new motives that belong to these periods are mostly floral. Busts and masks are the usual handle-plaques and spouts; heads and limbs of various animals are allotted certain decorative functions, as for instance the spirited mules' heads mentioned by Juve...
0
Metallurgy
In microwave sintering, heat is sometimes generated internally within the material, rather than via surface radiative heat transfer from an external heat source. Some materials fail to couple and others exhibit run-away behavior, so it is restricted in usefulness. A benefit of microwave sintering is faster heating for ...
0
Metallurgy
Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate genes, the proteins are 90% identical at the amino acid level. STAT5 proteins are involved i...
1
Gene expression + Signal Transduction
Scribing is the removal of maskant on the areas to be etched. For decorative applications, this is often done by hand through the use of a scribing knife, etching needle or similar tool; modern industrial applications may involve an operator scribing with the aid of a template or use computer numerical control to autom...
0
Metallurgy
The ability of the immune system to recognize molecules that are broadly shared by pathogens is, in part, due to the presence of immune receptors called toll-like receptors (TLRs) that are expressed on the membranes of leukocytes including dendritic cells, macrophages, natural killer cells, cells of the adaptive immuni...
1
Gene expression + Signal Transduction
Soluble adenylyl cyclase (sAC) is a regulatory cytosolic enzyme present in almost every cell. sAC is a source of cyclic adenosine 3’,5’ monophosphate (cAMP) – a second messenger that mediates cell growth and differentiation in organisms from bacteria to higher eukaryotes. sAC differentiates from the transmembrane adeny...
1
Gene expression + Signal Transduction
Laser peening (LP), or laser shock peening (LSP), is a surface engineering process used to impart beneficial residual stresses in materials. The deep, high-magnitude compressive residual stresses induced by laser peening increase the resistance of materials to surface-related failures, such as fatigue, fretting fatigue...
0
Metallurgy
CK2 typically appears as a tetramer of two α subunits; α being 42 kDa and α’ being 38 kDa, and two β subunits, each weighing in at 28 kDa. The β regulatory domain only has one isoform and therefore within the tetramer will have two β subunits. The catalytic α domains appear as an α or α’ variant and can either be forme...
1
Gene expression + Signal Transduction
Microstructure is the very small scale structure of a material, defined as the structure of a prepared surface of material as revealed by an optical microscope above 25× magnification. The microstructure of a material (such as metals, polymers, ceramics or composites) can strongly influence physical properties such as ...
0
Metallurgy
The Pidgeon process is a practical method for smelting magnesium. The most common method involves the raw material, dolomite being fed into an externally heated reduction tank and then thermally reduced to metallic magnesium using 75% ferrosilicon as a reducing agent in a vacuum. Overall the processes in magnesium smel...
0
Metallurgy
The TFs binding sites are physical DNA sites recognized by transcription factors within a genome, including enhancer, upstream activator (UAS) and operator sites that may bind repressors or activators.
1
Gene expression + Signal Transduction
In the regulation of heating and cooling, thermostats that operate over a wide range of temperatures are used. In these, one end of the bimetallic strip is mechanically fixed and attached to an electrical power source, while the other (moving) end carries an electrical contact. In adjustable thermostats another contact...
0
Metallurgy
The methylation of certain CpG clusters (i.e. DNA areas high in cytosine and guanine) regulate the transcriptional activity of nearby genes. That is, the methylation of a cluster(s) regulates its nearby gene by blocking it from making mRNAs and thereby the proteins encoded by these mRNAs. Studies find that the CMTM5 ge...
1
Gene expression + Signal Transduction
Copper does not require cleaning or maintenance. It is particularly suited for areas that are difficult or dangerous to access after installation.
0
Metallurgy
The CTCF insulator appears to have enhancer blocking activity via its 3D structure and have no direct connection with barrier activity. Vertebrates in particular appear to rely heavily on the CTCF insulator, however there are many different insulator sequences identified. Insulated neighborhoods formed by physical int...
1
Gene expression + Signal Transduction
The basic oxygen process developed outside of traditional "big steel" environment. It was developed and refined by a single man, Swiss engineer Robert Durrer, and commercialized by two small steel companies in allied-occupied Austria, which had not yet recovered from the destruction of World War II. In 1856, Henry Bess...
0
Metallurgy
Of the known types of bronze or brass, not distinguished in classical antiquity and interchangeably known in Latin as aes and in Greek as χαλκός, Corinthian bronze was the most valuable. Statues, vases and vessels, or other objects formed of this metal were priceless, of greater value than if they had been made of silv...
0
Metallurgy
Some invertebrates use calcium compounds for building their exoskeleton (shells and carapaces) or endoskeleton (echinoderm plates and poriferan calcareous spicules).
1
Gene expression + Signal Transduction
Bluing is a technique that can provide limited resistance to rusting for small steel items, such as firearms; for it to be successful, a water-displacing oil is rubbed onto the blued steel and other steel .
0
Metallurgy
A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic steps to modulate cell activity. The nervous system utilizes two types of receptors: metabotropic and ionotropic receptors. While ionotropic receptors form an io...
1
Gene expression + Signal Transduction
In September 2011, three NASA investigators claimed that they identified tin whiskers on the accelerator position sensors of sampled Toyota Camry models that could contribute to the "stuck accelerator" crashes affecting certain Toyota models during 2005–2010. This contradicted an earlier 10-month joint investigation by...
0
Metallurgy
Geometallurgy relates to the practice of combining geology or geostatistics with metallurgy, or, more specifically, extractive metallurgy, to create a spatially or geologically based predictive model for mineral processing plants. It is used in the hard rock mining industry for risk management and mitigation during ...
0
Metallurgy
Many different microscopy techniques are used in metallographic analysis. Prepared specimens should be examined with the unaided eye after etching to detect any visible areas that have responded to the etchant differently from the norm as a guide to where microscopical examination should be employed. Light optical micr...
0
Metallurgy
ASF/SF2 has been shown to have a critical function in heart development, embryogenesis, tissue formation, cell motility, and cell viability in general.
1
Gene expression + Signal Transduction
In metallurgy, a ladle is a bucket-shaped container or vessel used to transport and pour out molten metals. Ladles are often used in foundries and range in size from small hand-carried vessels that resemble a kitchen ladle and hold to large steelmill ladles that hold up to . Many non-ferrous foundries also use ceramic...
0
Metallurgy
Several properties make NiSi an important local contact material in the area of microelectronics, among them a reduced thermal budget, low resistivity of 13–14 μΩ·cm and a reduced Si consumption when compared to alternative compounds.
0
Metallurgy
In nickel-based superalloys, regions of NiAl (called γ' phase) precipitate out of the nickel-rich matrix (called γ phase) to give high strength and creep resistance. Many alloy formulations are available and they usually include other elements, such as chromium, molybdenum, and iron, in order to improve various propert...
0
Metallurgy
Each of the functional regions of TFIIB interacts with different parts of RNA polymerase II. The amino terminal B ribbon is located on dock domain of RNA polymerase II and extends in to the cleft towards the active site. Extending the B ribbon is the B reader that extends via the RNA exit tunnel to the binding site of ...
1
Gene expression + Signal Transduction
Recent studies have shown that decreased TFIIB levels do not affect transcription levels within cells, this is thought to be partially because over 90% of mammalian promoters do not contain a BRE or TATA box. However, it has been shown that TFIIB is vital to the in vitro transcription and regulation of the herpes simpl...
1
Gene expression + Signal Transduction
In 1994, Dunne was appointed as a Postdoctoral research associate in the Department of Mechanical Engineering, University of Manchester (UMIST), before being appointed a Research Fellowship at Hertford College, Oxford and the Department of Engineering Science, University of Oxford from 1996 until 2012. He became the de...
0
Metallurgy
miRBase is considered to be the gold-standard miRNA database—it stores miRNA sequences detected by thousand of experiments. In this database each miRNA is associated with a miRNA precursor and with one or two mature miRNA (-5p and -3p). In the past it had always been said that the same miRNA precursor generates the sam...
1
Gene expression + Signal Transduction
Thomas James Marrow (born 23 November 1966) is a British scientist who is a professor of nuclear materials at the University of Oxford and holds the James Martin Chair in Energy Materials. He specialises in physical metallurgy, micromechanics, and X-ray crystallography of engineering materials, mainly ceramic matrix co...
0
Metallurgy
There are several kinds of Dimetcote, designed for different working environments. * Dimetcote 21-5 * Dimetcote 3a * Dimetcote 9H * Dimetcote 9 * Dimetcote 11 * Dimetcote 302H * Dimetcote 4
0
Metallurgy
The C-terminus of RPB1 is appended to form the C-terminal domain (CTD). The carboxy-terminal domain of RNA polymerase II typically consists of up to 52 repeats of the sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. The domain stretches from the core of the RNAPII enzyme to the exit channel, this placement is effective due to its...
1
Gene expression + Signal Transduction
The New Jersey Zinc Company invented this process in 1930. The process take advantage of the relatively low boiling point of zinc () as compared to the impurities being removed in the first "column": iron and aluminium. Therefore, in the first column the zinc is heated above its boiling point and allowed to rise to a c...
0
Metallurgy
An induction furnace is an electrical furnace in which the heat is applied by induction heating of metal. Induction furnace capacities range from less than one kilogram to one hundred tons, and are used to melt iron and steel, copper, aluminum, and precious metals. The advantage of the induction furnace is a clean, e...
0
Metallurgy
The specific study of the non-ferrous metals used in past. Gold, silver and copper were the first to be used by ancient humans. Gold and copper are both found in their native state in nature, and were thus the first to be exploited as they did not need to be smelted from their ores. They could be hammered into sheets o...
0
Metallurgy
Null mutants die at an early gestational age (embryonic day 11.5). By investigating hypomorphic mutants (which can survive 2 days longer), it was found that placental defects were primarily lethal and that there were also defects in cardiac and hepatic development, but many other organs were normal
1
Gene expression + Signal Transduction
E.coli are shown to be more sensitive to accumulations of guanosine tetraphosphate than guanosine pentaphosphate. A complete absence of (p)ppGpp causes multiple amino acid requirements, poor survival of aged cultures, aberrant cell division, morphology, and immotility, as well as being locked in a growth mode during e...
1
Gene expression + Signal Transduction
Twenty-three out of 25 patients showed high expression of SFRP1 mRNA in leiomyoma than the matched normal myometrium. During the menstrual cycle, the level of SFRP1 mRNA in leiomyoma was highest in the follicular phase. Gonadotropin releasing hormone analogue (GnRHa) decreases estrogen secretion from the ovary. Patie...
1
Gene expression + Signal Transduction
The journal included reviews of research, books, and academic conferences, as well as primary results in the form of brief reports. It also reviewed what it considered to be notable aspects of patents and relevant scientific literature. Occasionally articles on the history, geological occurrences, and exploitation of p...
0
Metallurgy
S. pneumoniae is human pathogenic bacterium in which the process of genetic transformation was first described in the 1930s. In order for a bacterium to take up exogenous DNA from its surroundings, it must become competent. In S. pneumoniae, a number of complex events must occur to achieve a competent state, but it i...
1
Gene expression + Signal Transduction
Acute lymphoblastic leukemia (ALL) is a blood cancer of malignant B lymphocytes (termed B-cell ALL) or T lymphocytes (termed T-cell ALL) that typically occurs in infants and young children. In a three population-representative cohort study, NUTM1 gene rearrangements (i.e. fusion genes) occurred in 0.28 to 0.86% of pedi...
1
Gene expression + Signal Transduction
The IX Brigade, led by Okladnikov, worked in the Greater Balkan region of Turkmenistan, and in the plateau of Krasnovodsk. The finds at the Jebel rock shelter site near the Caspian Sea on the southwestern end of the Uly Balkan massif was a stratigraphic sequence of Mesolithic and Neolithic deposits, considered a model ...
0
Metallurgy
The earliest recorded metal employed by humans appears to be gold, which can be found free or "native". Small amounts of natural gold have been found in Spanish caves dating to the late Paleolithic period, 40,000 BC. Silver, copper, tin and meteoric iron can also be found in native form, allowing a limited amount of me...
0
Metallurgy
Ferroxyl indicator is a solution containing potassium hexacyanoferrate(III) and phenolphthalein. It turns blue in the presence of Fe ions, and pink in the presence of hydroxide ions. It can be used to detect metal oxidation, and is often used to detect rusting in various situations. It can be prepared by dissolving 10g...
0
Metallurgy
Besides the smelters named so far, the BBOC has been licensed to the operators of the Trail smelter in British Columbia, the Belledune smelter in New Brunswick, the Noyelles Godault smelter in France, the Korea Zinc zinc smelter in Onsan, South Korea, and the lead smelter at Chanderiya in India.
0
Metallurgy
Thermocouples ideally should be very simple measurement devices, with each type being characterized by a precise curve, independent of any other details. In reality, thermocouples are affected by issues such as alloy manufacturing uncertainties, aging effects, and circuit design mistakes/misunderstandings.
0
Metallurgy
In addition to treating copper concentrates, ISASMELT furnaces have also been built to treat secondary (scrap) copper materials.
0
Metallurgy
It is known through early Spanish accounts that native Ecuadorians used balsa rafts fitted with sails to travel along the northern Andean coast to trade. Indeed, the first king of Lambayeque, where axe-monies are known to have been manufactured, is said in ethnohistorical accounts to have arrived in the city by raft. T...
0
Metallurgy
The main application of Ellingham diagrams is in the extractive metallurgy industry, where it helps to select the best reducing agent for various ores in the extraction process, purification and grade setting for steel manufacturing. It also helps to guide the purification of metals, especially the removal of trace ele...
0
Metallurgy
Intermetallic compounds are generally brittle at room temperature and have high melting points. Cleavage or intergranular fracture modes are typical of intermetallics due to limited independent slip systems required for plastic deformation. However, there are some examples of intermetallics with ductile fracture modes ...
0
Metallurgy
Compacted oxide layer glaze describes the often shiny, wear-protective layer of oxide formed when two metals (or a metal and ceramic) are slid against each other at high temperature in an oxygen-containing atmosphere. The layer forms on either or both of the surfaces in contact and can protect against wear.
0
Metallurgy
Metals such as aluminum naturally form a passivating oxide layer which provides moderate protection against corrosion. The layer is strongly adherent to the metal surface, and it will regrow quickly if scratched off. In conventional anodizing, this layer of oxide is grown on the surface of the metal by the application...
0
Metallurgy
Often referred to as a bearing heater, the mains frequency unit employs standard transformer principles for its operation. An internal winding is wound around a laminated core similar to a standard mains transformer. The core is then passed through the work-piece and when the primary coil is energised, a magnetic flux ...
0
Metallurgy
Besides the ex vivo approach by the City of Hope National Medical Center discussed above, the Center for Infection and Immunity Amsterdam (CINIMA), the University of Amsterdam, the Netherlands, is extensively researching the composition of multi-cassette DNA constructs to tackle HIV.
1
Gene expression + Signal Transduction
The pillar was installed as a trophy in building the Quwwat-ul-Islam mosque and the Qutb complex by Sultan Iltutmish in the 13th century. Its original location, whether on the site itself or from elsewhere, is debated. According to the inscription of king Chandra, the pillar was erected at Vishnupadagiri (Vishnupada). ...
0
Metallurgy
In aluminium alloys containing magnesium, magnesium oxides (MgO), cuboids (MgAlO-cuboid) and metallurgical spinel (MgAlO-spinel) can form. They result from the reaction between magnesium and oxygen in the melt. More of them will form with time and temperature. Spinel can be highly detrimental because of its big size an...
0
Metallurgy
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin...
1
Gene expression + Signal Transduction
In the arts, silicon carbide is a popular abrasive in modern lapidary due to the durability and low cost of the material. In manufacturing, it is used for its hardness in abrasive machining processes such as grinding, honing, water-jet cutting and sandblasting. SiC provides a much sharper and harder alternative for san...
0
Metallurgy
At low temperatures, some metals can undergo a ductile-brittle transition which makes the material brittle and could lead to catastrophic failure during operation. This temperature is commonly called a ductile-brittle transition temperature or embrittlement temperature. Research has shown that low temperature embrittle...
0
Metallurgy
For the creation of dies for producing jewelry and badges, or blanking and piercing (through use of a pancake die) by the coinage (stamping) process, the positive master may be made from sterling silver, since (with appropriate machine settings) the master is significantly eroded and is used only once. The resultant ne...
0
Metallurgy
Bainite is a plate-like microstructure that forms in steels at temperatures of 125–550 °C (depending on alloy content). First described by E. S. Davenport and Edgar Bain, it is one of the products that may form when austenite (the face-centered cubic crystal structure of iron) is cooled past a temperature where it is n...
0
Metallurgy
Ribosomal frameshifting may be controlled by mechanisms found in the mRNA sequence (cis-acting). This generally refers to a slippery sequence, a RNA secondary structure, or both. A −1 frameshift signal consists of both elements separated by a spacer region typically 5–9 nucleotides long. Frameshifting may also be induc...
1
Gene expression + Signal Transduction
Froth flotation is a process for separating minerals from gangue by exploiting differences in their hydrophobicity. Hydrophobicity differences between valuable minerals and waste gangue are increased through the use of surfactants and wetting agents. The flotation process is used for the separation of a large range of ...
0
Metallurgy
In the late 1950s and early 1960s, the French molecular biologists François Jacob and Jacques Monod became the first to explain enzyme induction, in the context of the lac operon of Escherichia coli. In the absence of lactose, the constitutively expressed lac repressor protein binds to the operator region of the DNA an...
1
Gene expression + Signal Transduction