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The precipitation of a second phase within the lattice of a material creates physical blockades through which a dislocation cannot pass. The result is that the dislocation must bend (which requires greater energy, or a greater stress to be applied) around the precipitates, which inevitably leaves residual dislocation l...
0
Metallurgy
Distribution of STAT4 is restricted to myeloid cells, thymus and testis. In resting human T cells it is expressed at very low levels, but its production is amplified by PHA stimulation.
1
Gene expression + Signal Transduction
Pitting corrosion, or pitting, is extremely localized corrosion that leads to the creation of small holes in the material – nearly always a metal. The failures resulting from this form of corrosion can be catastrophic. With general corrosion it is easier to predict the amount of material that will be lost over time and...
0
Metallurgy
Labourers working in the smelting industry have reported respiratory illnesses inhibiting their ability to perform the physical tasks demanded by their jobs.
0
Metallurgy
Plants for the production of pre-reduced iron ore are known as direct reduction plants. The principle involves exposing iron ore to the reducing action of a high-temperature gas (around 1000 °C). This gas is composed of carbon monoxide and dihydrogen, the proportions of which depend on the production process. Generally...
0
Metallurgy
Bases: adenine (A), cytosine (C), guanine (G) and thymine (T) or uracil (U). Amino acids: Alanine (Ala, A), Arginine (Arg, R), Asparagine (Asn, N), Aspartic acid (Asp, D), Cysteine (Cys, C), Glutamic acid (Glu, E), Glutamine (Gln, Q), Glycine (Gly, G), Histidine (His, H), Isoleucine (Ile, I), Leucine (Leu, L), Lysine (...
1
Gene expression + Signal Transduction
Although the modern electric arc furnace is a highly efficient recycler of steel scrap, operation of an arc furnace shop can have adverse environmental effects. Much of the capital cost of a new installation will be devoted to systems intended to reduce these effects, which include: * Enclosures to reduce high sound l...
0
Metallurgy
These forms of AC have been reported in specific bacteria (Prevotella ruminicola and Rhizobium etli , respectively) and have not been extensively characterized. There are a few extra members (~400 in Pfam) known to be in class VI. Class VI enzymes possess a catalytic core similar to the one in Class III.
1
Gene expression + Signal Transduction
As in the standard code, initiation is most efficient at AUG. In addition, GUG and UUG starts are documented in archaea and bacteria. In Escherichia coli, UUG is estimated to serve as initiator for about 3% of the bacteriums proteins. CUG is known to function as an initiator for one plasmid-encoded protein (RepA) in...
1
Gene expression + Signal Transduction
If a dopant is added to the material (example: Nd in BaTiO) the impurity will tend to stick to the grain boundaries. As the grain boundary tries to move (as atoms jump from the convex to concave surface) the change in concentration of the dopant at the grain boundary will impose a drag on the boundary. The original con...
0
Metallurgy
Nickel titanium, also known as nitinol, is a metal alloy of nickel and titanium, where the two elements are present in roughly equal atomic percentages. Different alloys are named according to the weight percentage of nickel; e.g., nitinol 55 and nitinol 60. Nitinol alloys exhibit two closely related and unique propert...
0
Metallurgy
Tarnish is a thin layer of corrosion that forms over copper, brass, aluminum, magnesium, neodymium and other similar metals as their outermost layer undergoes a chemical reaction. Tarnish does not always result from the sole effects of oxygen in the air. For example, silver needs hydrogen sulfide to tarnish, although i...
0
Metallurgy
The melting point of iron is experimentally well defined for pressures less than 50 GPa. For greater pressures, published data (as of 2007) put the γ-ε-liquid triple point at pressures that differ by tens of gigapascals and 1000 K in the melting point. Generally speaking, molecular dynamics computer simulations of iron...
0
Metallurgy
Corrosion Science is a peer-reviewed scientific journal published by Elsevier in 16 issues per year. Established in 1961, it covers a wide range of topics in the study of pure/applied corrosion and corrosion engineering, including but not limited to oxidation, biochemical corrosion, stress corrosion cracking, and corro...
0
Metallurgy
Several methods for detecting the RB1 gene mutations have been developed including a method that can detect large deletions that correlate with advanced stage retinoblastoma.
1
Gene expression + Signal Transduction
The first two STAT proteins were identified in the interferon system. There are seven mammalian STAT family members that have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6. STAT1 homodimers are involved in type II interferon signalling, and bind to the GAS (Interferon-Gamma Activat...
1
Gene expression + Signal Transduction
The RNAP occasionally stops and starts moving backwards when it encounters a roadblock or some difficult sequences. When this happens, the EC gets stuck because the reactive 3 edge of the RNA is out of the active site. The transcript cleavage factor TFS (a TFIIS homolog) helps resolve this issue by generating a cut so ...
1
Gene expression + Signal Transduction
G protein can refer to two distinct families of proteins. Heterotrimeric G proteins, sometimes referred to as the "large" G proteins, are activated by G protein-coupled receptors and are made up of alpha (α), beta (β), and gamma (γ) subunits. "Small" G proteins (20-25kDa) belong to the Ras superfamily of small GTPases....
1
Gene expression + Signal Transduction
Brass is an alloy composed of copper and zinc, usually for sheet metal, and casting in the proportion of seven parts of the former to three of the latter. Such a combination secures a good, brilliant colour. There are, however, varieties of tone ranging from a pale lemon colour to a deep golden brown, which depends upo...
0
Metallurgy
The process of converting pig iron into wrought iron (also known as bar iron) was at that time carried out in a finery forge, which was fuelled by charcoal. Charcoal was a limited resource, but coal, more widely available, could not be used because the sulphur in coal would adversely affect the quality of the wrought i...
0
Metallurgy
*MRPL9 *MRPL1 *MRPL10 *MRPL11 *MRPL12 *MRPL13 *MRPL14 *MRPL15 *MRPL16 *MRPL17 *MRPL18 *MRPL19 *MRPL2 *MRPL20 *MRPL21 *MRPL22 *MRPL23 *MRPL24 *MRPL27 *MRPL28 *MRPL3 *MRPL30 *MRPL32 *MRPL33 *MRPL35 *MRPL36 *MRPL37 *MRPL38 *MRPL4 *MRPL40 *MRPL41 *MRPL42 *MRPL43 *MRPL44 *MRPL45 *MRPL46 *MRP...
1
Gene expression + Signal Transduction
Above the theoretical shear strength of the material, a type of defect-less flow can still occur, shearing the material. Dislocation motion through glide (any temperature) or dislocation creep (at high temperatures) is a typical mechanism found at high stresses in deformation maps.
0
Metallurgy
Recent excavations in Middle Ganges Valley show iron working in India may have begun as early as 1800 BCE. In the 5th century BCE, the Greek historian Herodotus observed that "Indian and the Persian army used arrows tipped with iron." Ancient Romans used armour and cutlery made of Indian iron. Pliny the Elder also ment...
0
Metallurgy
In sub-Saharan West Africa, there were only two known source of copper that were commercially viable: Dkra near Nioro, Mali and Takedda in Azelik, Niger. Akjoujt was a significant source of copper, but due to the lack of timber it lost its significance in early historic times. The sources for West Africa's copper came ...
0
Metallurgy
After initial sporadic work, archaeometallurgy was more widely institutionalised in the 1960s and 70s, with research groups in Britain (The British Museum, the UCL Institute of Archaeology, the Institute for Archeo-Metallurgical Studies (iams)), Germany (Deutsches Bergbau Museum) and the US (MIT and Harvard). Specialis...
0
Metallurgy
*Terne-plate is a similar product to tinplate, but the bath is not of tin, but of tin and lead mixed, the latter metal constituting from 7.59% of the whole. The name derives from "terne", meaning dull or tarnish. Terne-plates began to be produced in England about the middle of the 19th century, and became widely employ...
0
Metallurgy
In mammals, CPSF is a protein complex, consisting of six subunits: CPSF-160 (CPSF1), CPSF-100 (CPSF2), CPSF-73 (CPSF3), and CPSF-30 (CPSF4) kDa subunits, WDR33 and Fip1 (FIP1L1). The subunits form two components: mammalian polyadenylation specificity factors (mPSF) and mammalian cleavage factor (mCF). The mPSF is made ...
1
Gene expression + Signal Transduction
In metallurgy, the Scheil-Gulliver equation (or Scheil equation) describes solute redistribution during solidification of an alloy.
0
Metallurgy
In molecular genetics, an untranslated region (or UTR) refers to either of two sections, one on each side of a coding sequence on a strand of mRNA. If it is found on the 5 side, it is called the 5 UTR (or leader sequence), or if it is found on the 3 side, it is called the 3 UTR (or trailer sequence). mRNA is RNA that c...
1
Gene expression + Signal Transduction
Demethylases are enzymes that remove methyl (CH) groups from nucleic acids, proteins (particularly histones), and other molecules. Demethylases are important epigenetic proteins, as they are responsible for transcriptional regulation of the genome by controlling the methylation of DNA and histones, and by extension, th...
1
Gene expression + Signal Transduction
Chemokine receptors associate with G-proteins to transmit cell signals following ligand binding. Activation of G proteins, by chemokine receptors, causes the subsequent activation of an enzyme known as phospholipase C (PLC). PLC cleaves a molecule called phosphatidylinositol (4,5)-bisphosphate (PIP2) into two second me...
1
Gene expression + Signal Transduction
miR-324-5p is a reverse strand miRNA, meaning it is produced from the 5' end of the associated RNA, and spans from position 7,223,342 to 7,223,364 on chromosome 17. Its sequence is CGCAUCCCCUAGGGCAUUGGUG. miRNA forms following cleavage of pre-miRNA at the hairpin loop by the enzyme dicer within the cytosol. Interesting...
1
Gene expression + Signal Transduction
The following reactions successively convert hematite (from iron ore) into magnetite, magnetite into ferrous oxide, and ferrous oxide into iron by reduction with carbon monoxide or hydrogen. Carburizing produces cementite (FeC):
0
Metallurgy
*Ensembl: [http://www.ensembl.org/biomart/martview/4e6c01c28faed033db52d0d30e4c21ab] *OmicTools: [https://omictools.com/mtd-3-tool] *Transcriptome Browser: [http://tagc.univ-mrs.fr/tbrowser/] *ArrayExpress: [http://www.ebi.ac.uk/arrayexpress/]
1
Gene expression + Signal Transduction
Quorum quenching is the process of preventing quorum sensing by disrupting signalling. This is achieved by inactivating signalling enzymes, by introducing molecules that mimic signalling molecules and block their receptors, by degrading signalling molecules themselves, or by a modification of the quorum sensing signals...
1
Gene expression + Signal Transduction
The unlinked galR gene encodes the repressor for this system. A tetrameric GalR repressor binds to 2 operators, one located at +55 and one located at -60 relative to the PG1 start site. Looping of the DNA blocks the access of RNA polymerase to promoters and/or inhibits formation of the open complex. This looping requir...
1
Gene expression + Signal Transduction
E. coli has seven main sigma factors, five of which have a specific anti-sigma factor. The anti-sigma factor binding to its sigma factors depends upon environmental cues. This mechanism blocks the transcription of genes that are unnecessary in new conditions. The table below shows five sigma factors, what process it af...
1
Gene expression + Signal Transduction
To identify diverse post-transcriptional modifications of RNA molecules and determine the transcriptome-wide landscape of RNA modifications by means of next generation RNA sequencing, recently many studies have developed conventional or specialised sequencing methods. Examples of specialised methods are MeRIP-seq, m6A-...
1
Gene expression + Signal Transduction
A "refractory" gold ore is an ore that has ultra-fine gold particles disseminated throughout its gold occluded minerals. These ores are naturally resistant to recovery by standard cyanidation and carbon adsorption processes. These refractory ores require pre-treatment in order for cyanidation to be effective in recove...
0
Metallurgy
The Kesternich test is a common name for the corrosion test with sulfur dioxide (SO) under general moisture condensation. This test was developed in 1951 by Wilhelm Kesternich to simulate the damaging effects of acid rain. Acid rain and acidic industrial pollutants are corrosive and can degrade coatings and plated sur...
0
Metallurgy
The site was opened in 1931 by the Lindsay Light and Chemical Company. It processed ores like monazite to produce elements, including thorium and uranium. It also made gaslight mantles, and during World War II, hydrofluoric acid. In 1958, it became owned by American Potash and Chemical Company (AMPOT), which at one poi...
0
Metallurgy
Dynamic recrystallization (DRX) is a type of recrystallization process, found within the fields of metallurgy and geology. In dynamic recrystallization, as opposed to static recrystallization, the nucleation and growth of new grains occurs during deformation rather than afterwards as part of a separate heat treatment. ...
0
Metallurgy
While lists of noble metals can differ, they tend to cluster around the six platinum group metals (ruthenium, rhodium, palladium, osmium, iridium, platinum) plus gold. In addition to this terms function as a compound noun, there are circumstances where noble is used as an adjective for the noun metal'. A galvanic seri...
0
Metallurgy
The GLD-2 protein together with 136 proteins more, is involved in the molecular process of hematopoietic progenitor cell differentiation, in the human proteome. This is the process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a kind of cell types including myeloid p...
1
Gene expression + Signal Transduction
Oligonucleotides are chemically synthesized using building blocks called nucleoside phosphoramidites. These can be normal or modified nucleosides which have protecting groups to prevent their amines, hydroxyl groups and phosphate groups from interacting incorrectly. One phosphoramidite is added at a time, the 5 hydroxy...
1
Gene expression + Signal Transduction
A third group of genes in which mutations lead to a significant susceptibility to cancer is the class of landscaper genes. Products encoded by landscaper genes do not directly affect cellular growth, but when mutated, contribute to the neoplastic growth of cells by fostering stromal environments conducive to unregulat...
1
Gene expression + Signal Transduction
The increase in use of Terfenol-D in transducers required new production techniques that increased production rates and quality because the original methods were unreliable and small scale. There are four methods that are used to produce Terfenol-D, which are free stand zone melting, modified Bridgman, sintered powder ...
0
Metallurgy
According to metallurgist Jack Harris, "Oxidation is usually accompanied by a net expansion so that when it occurs in a confined space stresses are generated in the metal component itself or in any surrounding medium such as stone or cement. So much energy is released by oxidation that the stresses generated are of suf...
0
Metallurgy
Survivin is known to be expressed during fetal development and across most tumour cell types, but is rarely present in normal, non-malignant adult cells. Tamm et al. showed that survivin was expressed in all 60 different human tumour lines used in the National Cancer Institute's cancer drug-screening program, with the ...
1
Gene expression + Signal Transduction
The individual hearths are lined with refractory brick, and the rabble arms are typically a force-cooled metal alloy. The entire structure is enclosed in a cylindrical brick-lined steel shell.
0
Metallurgy
In certain cases, the plane stress model can be used in the analysis of gently curved surfaces. For example, consider a thin-walled cylinder subjected to an axial compressive load uniformly distributed along its rim, and filled with a pressurized fluid. The internal pressure will generate a reactive hoop stress on the...
0
Metallurgy
Thomas Whitwell (24 October 1837 – 5 August 1878) was a British engineer, inventor and metallurgist. Known as Tom, he was the third son of William and Sarah Whitwell of Kendal. Tom was initially educated at home via private tutors he was sent to the Quaker run York School at 10 years old. In 1858, at 16, he travelle...
0
Metallurgy
The working gristmill grinds wheat and corn into flour, which is available for sale during the twice-yearly shows. During the summer months, the museum grows sorghum cane, which is made into molasses for the fall show.
0
Metallurgy
Attenuators may be classified according to the type of molecule which induces the change in RNA structure. It is likely that transcription-attenuation mechanisms developed early, perhaps prior to the archaea/bacteria separation and have since evolved to use a number of different sensing molecules (the tryptophan biosyn...
1
Gene expression + Signal Transduction
The complex changes that the Schwann cell undergoes during the process of myelination of peripheral nerve fibers have been observed and studied by many. The initial envelopment of the axon occurs without interruption along the entire extent of the Schwann cell. This process is sequenced by the in-folding of the Schwa...
1
Gene expression + Signal Transduction
In most cases, splicing removes introns as single units from precursor mRNA transcripts. However, in some cases, especially in mRNAs with very long introns, splicing happens in steps, with part of an intron removed and then the remaining intron is spliced out in a following step. This has been found first in the Ultrab...
1
Gene expression + Signal Transduction
Mercury has been smelted from cinnabar for thousands of years. Mercury dissolves many metals, such as gold, silver, and tin, to form amalgams (an alloy in a soft paste or liquid form at ambient temperature). Amalgams have been used since 200 BC in China for gilding objects such as armor and mirrors with precious metals...
0
Metallurgy
In 1831, the East India Company officer William Elliott made a facsimile of the inscription. Based on this facsimile, in 1834, James Prinsep published a lithograph in the Journal of the Royal Asiatic Society of Great Britain and Ireland. However, this lithograph did not represent every single word of the inscription co...
0
Metallurgy
Pioneer factors can function passively, by acting as a bookmark for the cell to recruit other transcription factors to specific genes in condensed chromatin. This can be important for priming the cell for a rapid response as the enhancer is already bound by a pioneer transcription factor giving it a head start towards...
1
Gene expression + Signal Transduction
As of December 20, 2006, ORegAnno contained 4220 regulatory sequences (excluding deprecated records) for 2190 transcription factor binding sites, 1853 regulatory regions (enhancers, promoters, etc.), 170 regulatory polymorphisms, and 7 regulatory haplotypes for 17 different organisms (predominantly Drosophila melanogas...
1
Gene expression + Signal Transduction
The signal that starts the MAPK/ERK pathway is the binding of extracellular mitogen to a cell surface receptor. This allows a Ras protein (a Small GTPase) to swap a GDP molecule for a GTP molecule, flipping the "on/off switch" of the pathway. The Ras protein can then activate MAP3K (e.g., Raf), which activates MAP2K, w...
1
Gene expression + Signal Transduction
At atmospheric pressure, three allotropic forms of iron exist, depending on temperature: alpha iron (α-Fe, ferrite), gamma iron (γ-Fe, austenite), and delta iron (δ-Fe). At very high pressure, a fourth form exists, epsilon iron (ε-Fe, hexaferrum). Some controversial experimental evidence suggests the existence of a fif...
0
Metallurgy
Sintering and hot isostatic pressing are processing techniques used to densify materials from a loosely packed "green body" into a solid object with physically merged grains. Sintering occurs below the melting point, and causes adjacent particles to merge at their boundaries, creating a strong bond between them. In hot...
0
Metallurgy
Many alloys of industrial significance have some volume fraction of second phase particles, either as a result of impurities or from deliberate alloying additions. Depending on their size and distribution such particles may act to either encourage or retard recrystallization.
0
Metallurgy
The characteristics capable of supporting Type 1 pits were determined empirically by Lucey after examining the compositions of waters in which the pitting behaviour was known. They should be cold, less than 30°C, hard or moderately hard, 170 to 300 mg/L carbonate hardness, and organically pure. Organically pure waters ...
0
Metallurgy
# Excitatory synapse: Enhances the probability of depolarization in postsynaptic neurons and the initiation of an action potential. # Inhibitory Synapse: Diminishes the probability of depolarization in postsynaptic neurons and the initiation of an action potential. An influx of Na+ driven by excitatory neurotransmitter...
1
Gene expression + Signal Transduction
Pertussis toxin (PT) is a protein-based AB-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. Research suggests PT may have a therapeutic role in treating a number of common human ailm...
1
Gene expression + Signal Transduction
The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. EpoR is a 52kDa peptide with a single carbohydrate chain resulting in an approximately 56-57 kDa protein found on the surface of EPO responding cells. It is a member of the cytokine receptor family. EpoR pre-exists as dimers. T...
1
Gene expression + Signal Transduction
During quiescence, the DREAM complex represses G1/S and G2/M gene expression. In mammalian systems, chromatin-immunoprecipitation (ChIP) studies have revealed that DREAM components are found together at promoters of genes that peak in G1/S or G2/M phase. Abrogation of the DREAM complex on the other hand, led to increas...
1
Gene expression + Signal Transduction
The Museum of the History of Donetsk Metallurgical Plant was created in 1955, and it is located in the Technology House. The idea for its creation came from the director of the DMZ, Pavel Vasilyevich Andreev. The museum consists of more than 3000 exhibits. In 1971 the museum was awarded the title of national museum. Am...
0
Metallurgy
Pelletizing of animal feeds can result in pellets from (shrimp feeds), through to (poultry feeds) up to (stock feeds). The pelletizing of stock feed is done with the pellet mill machinery, which is done in a feed mill.
0
Metallurgy
Battens – the horizontal elements on "board and batten" shutters. Strap hinges usually mount centered on the battens. This is the standard construction approach for most barn doors. Butt mounted – hinges that mortise into the sides of the hinges – only the barrel of the hinge is visible when the shutter is in the close...
0
Metallurgy
Numerous destructive and non-destructive evaluation (NDE) methods exist for characterizing coatings. The most common destructive method is microscopy of a mounted cross-section of the coating and its substrate. The most common non-destructive techniques include ultrasonic thickness measurement, X-ray fluorescence (XRF)...
0
Metallurgy
Myristoylation is a lipidation modification where a myristoyl group, derived from myristic acid, is covalently attached by an amide bond to the alpha-amino group of an N-terminal glycine residue. Myristic acid is a 14-carbon saturated fatty acid (14:0) with the systematic name of n-tetradecanoic acid. This modificat...
1
Gene expression + Signal Transduction
There are two primary mTOR inhibitors used in the treatment of human cancers, temsirolimus and everolimus. mTOR inhibitors have found use in the treatment of a variety of malignancies, including renal cell carcinoma (temsirolimus) and pancreatic cancer, breast cancer, and renal cell carcinoma (everolimus). The complete...
1
Gene expression + Signal Transduction
In genetics and molecular biology, a corepressor is a molecule that represses the expression of genes. In prokaryotes, corepressors are small molecules whereas in eukaryotes, corepressors are proteins. A corepressor does not directly bind to DNA, but instead indirectly regulates gene expression by binding to repressors...
1
Gene expression + Signal Transduction
Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1. It has a crucial role in angiogenesis, therefore, making it an important protein for tumor growth, survival and metastasis ...
1
Gene expression + Signal Transduction
Gain of function mutation was first discovered in patients with chronic mucocutaneous candidiasis (CMC). This disease is characteristic with its symptoms as persistent infections of the skin, mucosae - oral or genital and nails infections caused by Candida, mostly Candida albicans. CMC may very often result from primar...
1
Gene expression + Signal Transduction
De la Pirotechnia is considered to be one of the first printed books on metallurgy to have been published in Europe. It was written in Italian and first published in Venice in 1540. The author was Vannoccio Biringuccio, a citizen of Siena, Italy, who died before it was published. Further editions were published in ...
0
Metallurgy
Wastewater pollutants discharged by iron and steel mills includes gasification products such as benzene, naphthalene, anthracene, cyanide, ammonia, phenols and cresols, together with a range of more complex organic compounds known collectively as polycyclic aromatic hydrocarbons (PAH). Treatment technologies include re...
0
Metallurgy
These techniques employ electric currents to drive or enhance sintering. English engineer A. G. Bloxam registered in 1906 the first patent on sintering powders using direct current in vacuum. The primary purpose of his inventions was the industrial scale production of filaments for incandescent lamps by compacting tung...
0
Metallurgy
RNA polymerase III appears to be essential for homologous recombinational repair of DNA double-strand breaks. RNA polymerase III catalyzes the formation of a transient RNA-DNA hybrid at double strand breaks, an essential intermediate step in homologous recombination mediated double-strand break repair. This step protec...
1
Gene expression + Signal Transduction
Atomic hydrogen diffusing through metals may collect at internal defects like inclusions and laminations and form molecular hydrogen. High pressures may be built up at such locations due to continued absorption of hydrogen leading to blister formation, growth and eventual bursting of the blister. Such hydrogen induced ...
0
Metallurgy
A nonstop mutation, also called a stop-loss variant, is a point mutation that occurs within a stop codon. Nonstop mutations cause the continued translation of an mRNA strand into what should be an untranslated region. Most polypeptides resulting from a gene with a nonstop mutation lose their function due to their extre...
1
Gene expression + Signal Transduction
This effect is significantly less common in ceramics which are typically more resilient to chemical attack. Although phase changes are common in ceramics under stress these usually result in toughening rather than failure (see Zirconium dioxide). Recent studies have shown that the same driving force for this toughening...
0
Metallurgy
Crevice corrosion refers to corrosion occurring in occluded spaces such as interstices in which a stagnant solution is trapped and not renewed. These spaces are generally called crevices. Examples of crevices are gaps and contact areas between parts, under gaskets or seals, inside cracks and seams, spaces filled with ...
0
Metallurgy
The limitations of currently available rapalogs have led to new approaches to mTOR targeting. Studies suggest that mTOR inhibitors may have anticancer activity in many cancer types, such as RCC, neuroendocrine tumors, breast cancer, hepatocellular carcinoma, sarcoma, and large B-cell lymphoma. One major limitation for ...
1
Gene expression + Signal Transduction
Carbon in pulp (CIP) is an extraction technique for recovery of gold which has been liberated into a cyanide solution as part of the gold cyanidation process. Introduced in the early 1980s, Carbon in Pulp is regarded as a simple and cheap process. As such it is used in most industrial applications where the presence o...
0
Metallurgy
While the Superstack lowered the ground-level pollution in the city, it has dispersed sulphur dioxide, and nitrogen dioxide gases over a much larger area. Though not the single source of lake acidification, it appears even the heavily industrialized Ohio Valley has contributed to the ecological problem of lakes as far ...
0
Metallurgy
By the early 19th century the puddling process was widespread. Until technological advances made it possible to work at higher heats, slag impurities could not be removed entirely, but the reverberatory furnace made it possible to heat iron without placing it directly in the fire, offering some degree of protection fro...
0
Metallurgy
A typical thermal spray system consists of the following: *Spray torch (or spray gun) – the core device performing the melting and acceleration of the particles to be deposited *Feeder – for supplying the powder, wire or liquid to the torch through tubes. *Media supply – gases or liquids for the generation of the flame...
0
Metallurgy
Ethylene signaling pathway is a signal transduction in plant cells to regulate important growth and developmental processes. Acting as a plant hormone, the gas ethylene is responsible for promoting the germination of seeds, ripening of fruits, the opening of flowers, the abscission (or shedding) of leaves and stress re...
1
Gene expression + Signal Transduction
New mTOR-specific inhibitors came forth from screening and drug discovery efforts. These compounds block activity of both mTOR complexes and are called mTORC1/mTORC2 dual inhibitors. Compounds with this characteristics such as sapanisertib (codenamed INK128), AZD8055, and AZD2014 have entered clinical trials. A series ...
1
Gene expression + Signal Transduction
Gold, copper and tumbaga objects started being produced in Panama and Costa Rica between 300–500 CE. Open-molded casting with oxidation gilding and cast filigrees were in use. By 700–800 CE, small metal sculptures were common and an extensive range of gold and tumbaga ornaments constituted the usual regalia of pe...
0
Metallurgy
In the process of smelting, inorganic chlorides, fluorides (see fluorite), limestone and other materials are designated as "fluxes" when added to the contents of a smelting furnace or a cupola for the purpose of purging the metal of chemical impurities such as phosphorus, and of rendering slag more liquid at the smelti...
0
Metallurgy
A mechanism involving arbitrium has recently been described in bacteriophages infecting several Bacillus species. The viruses communicate with each other to ascertain their own density compared to potential hosts. They use this information to decide whether to enter a lytic or lysogenic life-cycle.This decision is cruc...
1
Gene expression + Signal Transduction
Copper tubes have been used to distribute potable water within building for many years and hundreds of miles are installed throughout Europe every year. The long life of copper when exposed to natural waters is a result of its thermodynamic stability, its high resistance to reacting with the environment, and the format...
0
Metallurgy
The possibility has been proposed and studied, both theoretically and experimentally, of implementing an orthogonal system inside cells independent of the cellular genetic material in order to make a completely safe system, with the possible increase in encoding potentials. Several groups have focused on different aspe...
1
Gene expression + Signal Transduction
The first computational model of dendritic solidification was published by Kobayashi, who used a phase-field model to solve two coupled partial differential equations describing the evolution of the phase-field, (with in the liquid phase and in the solid phase), and the temperature field, , for a pure material in tw...
0
Metallurgy
A prill is a small aggregate or globule of a material, most often a dry sphere, formed from a melted liquid through spray crystallization. Prilled is a term used in mining and manufacturing to refer to a product that has been pelletized. ANFO explosive typically comprises ammonium nitrate prills mixed with #2 fuel oil....
0
Metallurgy