query stringclasses 190 values | positive listlengths 1 5 | negative listlengths 4 4 | system stringlengths 69 2.19k |
|---|---|---|---|
What is the biomedical concept corresponding to 'staphylococcus aureus'? | [
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus col (staphylococcus aureus subsp. aureus col)",
"staphylococcus sp. s"
] | Given the context 'A novel DNA-binding protein modulating methicillin resistance in Staphylococcus aureus
Abstract
Background
Methicillin resistance in Staphylococcus aureus is conferred by the mecA-encoded penicillin-binding protein PBP2a.', answer the user's query. |
What is the biomedical concept corresponding to 'staphylococcus aureus'? | [
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus col (staphylococcus aureus subsp. aureus col)",
"staphylococcus sp. s"
] | Given the context 'A novel DNA-binding protein modulating methicillin resistance in Staphylococcus aureus
Abstract
Background
Methicillin resistance in Staphylococcus aureus is conferred by the mecA-encoded penicillin-binding protein PBP2a.', answer the user's query. |
What is the biomedical concept corresponding to 's. aureus'? | [
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)",
"staphylococcus aureus subsp. anaerobius (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus col (staphylococcus aureus subsp. aureus col)",
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus faecalis ('staphylococcus faecalis')"
] | Given the context 'Nonpolar deletion of SA1665, in heterogeneously methicillin resistant S. aureus (MRSA) of different genetic backgrounds, increased methicillin resistance levels in a strain dependent manner.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Nonpolar deletion of SA1665, in heterogeneously methicillin resistant S. aureus (MRSA) of different genetic backgrounds, increased methicillin resistance levels in a strain dependent manner.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Conclusion
SA1665 is a new chromosomal factor which influences methicillin resistance in MRSA.', answer the user's query. |
What is the biomedical concept corresponding to 's. aureus'? | [
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)",
"staphylococcus aureus subsp. anaerobius (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus col (staphylococcus aureus subsp. aureus col)",
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus faecalis ('staphylococcus faecalis')"
] | Given the context 'Background
Methicillin resistant S. aureus (MRSA) are an ever increasing threat, both in clinical settings and more recently as an emerging community acquired pathogen.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Background
Methicillin resistant S. aureus (MRSA) are an ever increasing threat, both in clinical settings and more recently as an emerging community acquired pathogen.', answer the user's query. |
What is the biomedical concept corresponding to 's. aureus'? | [
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)",
"staphylococcus aureus subsp. anaerobius (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus col (staphylococcus aureus subsp. aureus col)",
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus faecalis ('staphylococcus faecalis')"
] | Given the context 'In S. aureus, methicillin resistance is conferred by an acquired, β-lactam-insensitive penicillin-binding protein (PBP), PBP2a', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Heterogeneously resistant MRSA, when exposed to β-lactam antibiotics, segregate highly resistant subpopulations, which are much more resistant than the majority of the cells [10].', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'The vast MIC differences between MRSA strains, the population heterogeneity within single strains and the dependence of resistance levels on external factors are reflected in these many structural genes and global regulators, which can influence resistance levels.
', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'While typically considered nosocomial pathogens, new faster growing and apparently more virulent MRSA have begun spreading in the community.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Interestingly, these emerging strains often express very low methicillin resistance, e.g. the MRSA clone spreading amongst intravenous drug users in the Zurich area, which has an in vitro doubling time of 25 min, but oxacillin MICs of only 0.5 to 4 μg/ml', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'To identify potential factors involved in mecA regulation or methicillin resistance levels in such an extremely low level resistant MRSA, we performed DNA-binding protein purification assays, using the mecA operator region as bait.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Results
Identification of SA1665
MRSA strain CHE482 is the type strain for the so-called "drug clone" spreading amongst intravenous drug users in the Zurich area', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'However, like most other low-level resistant MRSA, it can segregate a small proportion of higher resistant subclones in the presence of β-lactams.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'We hypothesized that regulation of methicillin resistance in such low-level resistant clonal lineages may differ qualitatively from classical heterogeneously- or highly-resistant MRSA.
', answer the user's query. |
What is the biomedical concept corresponding to 's. aureus'? | [
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)",
"staphylococcus aureus subsp. anaerobius (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus col (staphylococcus aureus subsp. aureus col)",
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus faecalis ('staphylococcus faecalis')"
] | Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', answer the user's query. |
What is the biomedical concept corresponding to 's. haemolyticus'? | [
"staphylococcus haemolyticus"
] | [
"streptococcus hemolyticus (streptococcus pyogenes)",
"actinobacillus equuli subsp. haemolyticus (actinobacillus equuli-like)",
"rodentibacter haemolyticus",
"haemophilus parahaemolyticus"
] | Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', answer the user's query. |
What is the biomedical concept corresponding to 's. epidermidis'? | [
"micrococcus epidermidis (staphylococcus epidermidis)",
"albococcus epidermidis (staphylococcus epidermidis)",
"staphylococcus epidermidis (staphylococcus epidermidis albus)",
"staphylococcus epidermidis albus (staphylococcus epidermidis)"
] | [
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus simulans staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus)",
"staphylococcus sp. s"
] | Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', answer the user's query. |
What is the biomedical concept corresponding to 's. saprophyticus'? | [
"staphylococcus saprophyticus (staphylococcus saprophyticus subsp. bovis)",
"staphylococcus saprophyticus subsp. bovis (staphylococcus saprophyticus)"
] | [
"streptomyces saprophyticus",
"staphylococcus hominis",
"roussoella saprophytica",
"pleurotheciella saprophytica"
] | Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', answer the user's query. |
What is the biomedical concept corresponding to 'bacillus licheniformis'? | [
"bacillus licheniformis (denitrobacillus licheniformis)",
"clostridium licheniforme (bacillus licheniformis)",
"denitrobacillus licheniformis (bacillus licheniformis)"
] | [
"bacillus licheniformis dsm 13 (bacillus licheniformis dsm 13 = atcc 14580)",
"bacillus licheniformis f1-1",
"bacillus licheniformis g-1 (bacillus paralicheniformis g-1)",
"bacillus licheniformis atcc 14580 (bacillus licheniformis dsm 13 = atcc 14580)"
] | Given the context 'Conversely, there were no orfs highly similar to SA1665 found in other bacterial species, with the most similar sequences found in Bacillus licheniformis DSM13 and Desulfitobacterium hafniense Y51, which shared only 64% and 59% similarity, respectively.
', answer the user's query. |
What is the biomedical concept corresponding to 'desulfitobacterium hafniense y51'? | [
"desulfitobacterium hafniense y51 (desulfitobacterium hafniense strain y51)",
"desulfitobacterium sp. y51 (desulfitobacterium hafniense y51)",
"desulfitobacterium hafniense strain y51 (desulfitobacterium hafniense y51)",
"desulfitobacterium hafniense str. y51 (desulfitobacterium hafniense y51)"
] | [
"desulfitobacterium hafniense (desulfitobacterium frappieri)",
"desulfitobacterium frappieri (desulfitobacterium hafniense)",
"desulfitobacterium dehalogenans dsm 9161 (desulfitobacterium dehalogenans atcc 51507)",
"desulfitobacterium hafniense dsm 10664 (desulfitobacterium hafniense dcb-2)"
] | Given the context 'Conversely, there were no orfs highly similar to SA1665 found in other bacterial species, with the most similar sequences found in Bacillus licheniformis DSM13 and Desulfitobacterium hafniense Y51, which shared only 64% and 59% similarity, respectively.
', answer the user's query. |
What is the biomedical concept corresponding to 'e. coli strain bl21'? | [
"escherichia coli strain bl21 (escherichia coli bl21)",
"escherichia coli bl21 (escherichia coli strain bl21)",
"escherichia coli str. bl21 (escherichia coli bl21)"
] | [
"escherichia coli strain bl21(de3) (escherichia coli bl21(de3))",
"escherichia coli bl21(de3) (escherichia coli strain bl21(de3))",
"escherichia coli str. bl21(de3) (escherichia coli bl21(de3))",
"escherichia coli strain bl21-gold(de3)plyss ag (escherichia coli 'bl21-gold(de3)plyss ag')"
] | Given the context 'Crude protein extracts of E. coli strain BL21, carrying the empty plasmid (pET28nHis6) or pME20 (pET28nHis6-SA1665) which expressed nHis6-SA1665 upon induction with IPTG, were incubated with the 161-bp biotinylated-DNA fragment previously used as bait in the DNA-binding protein assay.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Effect of SA1665 deletion on β-lactam resistance
To analyse the effect of SA1665 inactivation on methicillin resistance, nonpolar markerless deletions of SA1665 (Figure 1B) were constructed in a selection of clinical MRSA isolates, which varied in their genetic background, SCCmec type, and mecA regulation [24].', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Discussion
Methicillin resistance in MRSA is primarily dependent on the presence of the mecA gene, however, resistance levels are generally governed by strain-specific factors including mecA regulatory elements and other chromosomal fem/aux factors which either enhance or repress the expression of resistance.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'The impact of deleting SA1665 in MRSA was extremely strain specific, underlining the importance of the genetic background in governing the final methicillin resistance levels of MRSA, and demonstrating the large genomic variability between different strain lineages.
', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'The impact of deleting SA1665 in MRSA was extremely strain specific, underlining the importance of the genetic background in governing the final methicillin resistance levels of MRSA, and demonstrating the large genomic variability between different strain lineages.
', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'Conclusion
SA1665 is a previously uncharacterised DNA-binding protein that has a negative effect on β-lactam resistance in MRSA.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'However, while nonpolar deletion of SA1665 was shown to increase oxacillin resistance levels in several heterogeneously resistant MRSA, its deletion had no effect on mecA transcription or PBP2a production.', answer the user's query. |
What is the biomedical concept corresponding to 'e. coli bl21'? | [
"escherichia coli strain bl21 (escherichia coli bl21)",
"escherichia coli bl21 (escherichia coli strain bl21)",
"escherichia coli str. bl21 (escherichia coli bl21)"
] | [
"escherichia coli strain bl21(de3) (escherichia coli bl21(de3))",
"escherichia coli bl21(de3) (escherichia coli strain bl21(de3))",
"escherichia coli str. bl21(de3) (escherichia coli bl21(de3))",
"escherichia coli strain bl21-gold(de3)plyss ag (escherichia coli 'bl21-gold(de3)plyss ag')"
] | Given the context 'The resulting plasmid, pME20, was transformed into E. coli BL21 for expression of recombinant nHis6-SA1665 protein.', answer the user's query. |
What is the biomedical concept corresponding to 'yeast'? | [
"saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883)",
"saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (saccharomyces cerevisiae)",
"baker's yeast (saccharomyces cerevisiae)",
"mycoderma cerevisiae (saccharomyces cerevisiae)",
"brewer's yeast (saccharomyces ce... | [
"true yeasts (saccharomycotina)",
"saccharomyces cerevisiae or paradoxus (saccharomyces cf. cerevisiae/paradoxus)",
"saccharomyces lactis (kluyveromyces lactis)",
"saccharomyces albicans (candida albicans)"
] | Given the context 'To maximise the abundance of soluble protein produced, cultures were grown in osmotic shock medium at 37°C (1 g/l NaCl, 16 g/l tryptone, 10 g/l yeast, 1 M sorbitol, 10 mM betaine, modified from [33]) to an OD600 nm of 0.5, cooled briefly on ice, then induced by adding 100 μM IPTG and growing overnight at 22°C.', answer the user's query. |
What is the biomedical concept corresponding to 'e. coli'? | [
"e. coli (escherichia coli)",
"bacterium coli (escherichia coli)",
"bacillus coli (escherichia coli)",
"escherichia coli (escherichia/shigella coli)",
"enterococcus coli (escherichia coli)"
] | [
"escherichia",
"escherichia faecalis ('escherichia faecalis')",
"enterobacteria (enterobacteriaceae)",
"'escherichia faecalis' (escherichia faecalis)"
] | Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 and pBUS1 [37], creating the complementing plasmids pME26 and pME27, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 's. aureus'? | [
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)",
"staphylococcus aureus subsp. anaerobius (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus col (staphylococcus aureus subsp. aureus col)",
"staphylococcus staphylolyticus (staphylococcus simulans bv. staphylolyticus)",
"staphylococcus faecalis ('staphylococcus faecalis')"
] | Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 and pBUS1 [37], creating the complementing plasmids pME26 and pME27, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'mrsa'? | [
"micrococcus aureus (staphylococcus aureus)",
"staphylococcus pyogenes aureus (staphylococcus aureus)",
"staphylococcus aureus (staphylococcus aureus subsp. anaerobius)",
"micrococcus pyogenes (staphylococcus aureus)"
] | [
"staphylococcus aureus subsp. aureus col (staphylococcus aureus col)",
"staphylococcus aureus str. pa (staphylococcus aureus pa)",
"staphylococcus aureus m1",
"staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300)"
] | Given the context 'PBP2a detection was performed using monoclonal PBP2a antibody (1:20000) from the MRSA-screen kit (Denka Seiken).
', answer the user's query. |
What is the biomedical concept corresponding to 'caenorhabditis elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"caenorhabditis",
"drosophila elegans",
"caenorhabditis sp.",
"elegans subgroup (in: flies)"
] | Given the context 'The Caenorhabditis elegans genome contains monomorphic minisatellites and simple sequences.
', answer the user's query. |
What is the biomedical concept corresponding to 'caenorhabditis elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"caenorhabditis",
"drosophila elegans",
"caenorhabditis sp.",
"elegans subgroup (in: flies)"
] | Given the context 'Here we demonstrate the presence of sequences in the genome of the nematode Caenorhabditis elegans which are homologous to two sets of short sequence DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'caenorhabds elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"enyo elegans (zodarion elegans)",
"uronema elegans",
"caenorhabditis sp.",
"zodarion elegans (enyo elegans)"
] | Given the context 'Images
Volume 17 Number 23 1989 Nucleic Acids Research
The Caenorhabds elegans genome contains monomorphic minisatellites and simple sequences Andrd G.Uitterlinden, P.Eline Slagboom, Thomas E.Johnsonl and Jan Vijg
Department of Molecular Biology, TNO Institute for Experimental Gerontology, PO Box 5815, 2280 HV Rijswijk, The Netherlands and lInstitute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
Received October 27, 1989; Accepted November 3, 1989
ABSTRACT
Many species have been shown to contain tandemly repeated short sequence DNA kinown as minisatellites and simple sequence motifs.', answer the user's query. |
What is the biomedical concept corresponding to 'caenorhabditis elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"caenorhabditis",
"drosophila elegans",
"caenorhabditis sp.",
"elegans subgroup (in: flies)"
] | Given the context 'Here we demonstrate the presence of sequences in the genome of the nematode Caenorhabditis elegans which are homologous to two sets of short sequence DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'caenorhabditis elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"caenorhabditis",
"drosophila elegans",
"caenorhabditis sp.",
"elegans subgroup (in: flies)"
] | Given the context 'Here we demonstrate that the genome of the nematode Caenorhabditis elegans contains sequences that are homologous to the minisatellite core sequence 33.6 (1) and to the simple sequence motif (AGC)n.', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'Surprisingly, these sequences did not display polymorphism when two independent C. elegans strains, Bristol and Bergerac, were compared.
', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'Nucleic Acids Research
C. elegans
N 0$ 8
_ _
: , s , ..e :*. ,~ :::::
.', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'I and Eco RI digested genomic DNA isolated from the two C. elegans strains Bristol (N) and Bergerac (B).', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'In Figure 1 the hybridization patterns are shown of C. elegans genomic DNA digested with Hae II, Rsa I and Eco RI, and subsequently hybridized to minisatellite core probe 33.6, the simple sequence probe (AGC)n and Tcl.', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'However, identical hybridization patterns for the two strains with the three enzymes tested indicated that in C. elegans these sequences are monomorphic (Fig. 1).', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'Based on the number of hybridizing bands we estimate the C. elegans genome to contain about 30 33.6 homologous loci and about 20 (AGC)n homologous loci.
', answer the user's query. |
What is the biomedical concept corresponding to 'humans'? | [
"human (homo sapiens)",
"homo sapiens (human)"
] | [
"humans (homo)",
"homo (humans)",
"primate (primates)",
"macrobiotus sapiens"
] | Given the context 'It should be noted, however, that at least in humans, a substantial part of the minisatellites detected by core probes also displays high levels of monomorphism as analysed by cloning (1) or by two-dimensional DNA fingerprinting (5).
', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'Indeed, Eide and Anderson (7) showed that tandemly repeated duplications in the unc-54 gene of C. elegans revert at high frequencies.', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'A more likely explanation for the monomorphic nature of the sequences detected with 33.6 and (AGC)n in C. elegans is selection against sequence variants at these loci.', answer the user's query. |
What is the biomedical concept corresponding to 'c. elegans'? | [
"caenorhabditis elegans (rhabditis elegans)",
"rhabditis elegans (caenorhabditis elegans)"
] | [
"elegans subgroup (in: flies)",
"caenorhabditis",
"drosophila elegans",
"elegans subgroup (in: mosquitos)"
] | Given the context 'An important step in understanding this phenomenon will therefore be the isolation and analysis of individual homologous minisatellite and simple sequence loci from a genomic library of C. elegans.
', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In the second study, adult (3–6 m) BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', answer the user's query. |
What is the biomedical concept corresponding to 'escherichia coli'? | [
"e. coli (escherichia coli)",
"bacterium coli (escherichia coli)",
"bacillus coli (escherichia coli)",
"escherichia coli (escherichia/shigella coli)",
"enterococcus coli (escherichia coli)"
] | [
"escherichia",
"escherichia faecalis ('escherichia faecalis')",
"enterobacteria (enterobacteriaceae)",
"escherichia sp."
] | Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In the final study, adult and aged BALB/c mice were treated with the same minocycline and LPS injection regimen and markers of neuroinflammation were determined.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Moreover, minocycline facilitated the recovery from sickness behavior (i.e., anorexia, weight loss, and social withdrawal) and prevented anhedonia in adult mice challenged with LPS.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Finally, in aged mice, where exaggerated neuroinflammation was elicited by LPS, minocycline pretreatment was still effective in markedly reducing mRNA levels of IL-1β, TLR2 and IDO in the hippocampus.
', answer the user's query. |
What is the biomedical concept corresponding to 'rats'? | [
"rats (rattus norvegicus) (rattus norvegicus)",
"rattus norvegicus (rats (rattus norvegicus))",
"rat (rattus norvegicus) (rattus norvegicus)",
"norway rat (rattus norvegicus)",
"brown rat (rattus norvegicus)"
] | [
"rats (rattus) (rattus)",
"rat (rattus) (rattus)",
"house rat (rattus rattus)",
"rattus (rats (rattus))"
] | Given the context 'Moreover, in the brain of rats, minocycline abrogates microglial expression of CD11b and MHC II through a protein kinase-c dependent mechanism [45].', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Moreover, our data show that minocycline pretreatment attenuated LPS-induced weight loss, social withdrawal, and anhedonia in adult mice.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'The attenuation of sickness behavior was paralleled with minocycline dependent decrease in markers of neuroinflammation (IL-1β, TLR2, and IDO) in adult and aged mice.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Methods
Animals
Male BALB/c mice, adults (3 month old) and juvenile (3–4 week old) were purchased from Harlan (Indianapolis, IN).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'For age comparisons, male BALB/c mice (3–4 and 20–22 month old) were purchased from the National Institute on Aging specific pathogen free colony.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Upon arrival, mice were individually housed in polypropylene cages and maintained at 21°C under a 12 h light: 12 h dark cycle with ad libitum access to water and rodent chow.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'At the end of each study, mice were examined postmortem for gross signs of disease (e.g., splenomeglia or tumors).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Data from mice determined to be unhealthy were excluded from analysis (< 5%).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Mice were euthanized by CO2 asphyxiation and whole brains were collected.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Sucrose preference
To assess sucrose preference, mice were provided two solutions, water or water supplemented with 2% sucrose, in 50 ml conical tubes with stoppers fitted with ball-type sipper tubes.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Prior to testing conditions, all mice were acclimated to the two bottle test choice.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'All mice drank both the water and the 2% sucrose solution, but preferred drinking the sucrose over the water (data not shown).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'On the day of testing, mice were fluid and food deprived for 2 h prior to testing [50].', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In brief, mice were euthanized by CO2 asphyxiation and blood was collected by cardiac puncture into EDTA coated syringes.', answer the user's query. |
What is the biomedical concept corresponding to 'mouse'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mouse (mus <genus>)",
"mice (mus <genus>) (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'For all mouse studies, minocycline (Sigma, St. Louis, MO) was dissolved in sterile water and sonicated to ensure complete solubilization.', answer the user's query. |
What is the biomedical concept corresponding to 'mouse'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mouse (mus <genus>)",
"mice (mus <genus>) (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', answer the user's query. |
What is the biomedical concept corresponding to 'escherichia coli'? | [
"e. coli (escherichia coli)",
"bacterium coli (escherichia coli)",
"bacillus coli (escherichia coli)",
"escherichia coli (escherichia/shigella coli)",
"enterococcus coli (escherichia coli)"
] | [
"escherichia",
"escherichia faecalis ('escherichia faecalis')",
"enterobacteria (enterobacteriaceae)",
"escherichia sp."
] | Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'The LPS dosage was selected because it elicits a proinflammatory cytokine response in the brain resulting in mild transient sickness behavior in adult mice [13,53].', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In the second study, adult male BALB/c mice received an i.p. injection with vehicle or minocycline for three consecutive days.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In a related, but separate study, adult mice were treated with minocycline and LPS as described and anhedonia was assessed 24–39 h following i.p. injection of saline or LPS (0.33 mg/kg) (n = 15).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In the third study, adult BALB/c mice were treated with minocycline and then LPS as described.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Mice were euthanized by CO2 asphyxiation 4 later.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In a final study, adult (3–4 month old) or aged (20–22 month old) male BALB/c mice were treated with minocycline and LPS as described and euthanized 4 h later.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'LPS-induced TLR2 surface expression on microglia is reduced by minocycline
Because minocycline attenuated LPS-induced cytokine secretion and TLR2 mRNA expression in BV-2 cells we next sought to determine if minocycline suppresses markers of microglial activation in the brain of mice.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Mice were injected i.p.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In this experiment, adult mice were treated with minocycline and LPS as described.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'For example, at 8 h post LPS, social exploration was reduced by 35% in minocycline pretreated mice given LPS compared to a 67% reduction in vehicle pretreated mice given LPS (P < 0.001).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'For example, at 8 h post LPS, social exploration was reduced by 35% in minocycline pretreated mice given LPS compared to a 67% reduction in vehicle pretreated mice given LPS (P < 0.001).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'While minocycline administration alone reduced food intake and body weight in control mice (P < 0.05, for each), it also protected against LPS-associated anorexia (Mino × LPS interaction, F(1, 60)', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In this experiment, mice were subjected to the same minocycline injection regimen and LPS challenge as above and sucrose preference was assessed 24–39 h post LPS injection.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'By 24 h post LPS injection, food and water intake returned to baseline and LPS treated mice still exhibited a marked reduction in sucrose preference from 24–39 h (F(1,59) = 14.3, P < 0.003).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'For example, minocycline pretreated mice injected with LPS maintained the same strong preference for sucrose as saline and minocycline controls (i.e., approximately 85% preference).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In this experiment, mice were subjected to the minocycline injection regimen and LPS challenge as above and cytokine mRNA levels were determined in the cortex and hippocampus 4 h after LPS injection.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In mice pretreated with vehicle, LPS markedly increased IL-1β mRNA levels in the hippocampus (F(1,31)', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'The LPS-induced IL-1β mRNA expression was reduced in both brain regions in mice receiving minocycline prior to LPS injection: (hippocampus, F(1,31)', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'It is important to note that IDO mRNA was undetected in saline treated mice.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Therefore, the fold IDO change was relative to the IDO mRNA levels in mice receiving minocycline prior to LPS.
', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Minocycline attenuates LPS-induced exaggerated neuroinflammation in aged mice
Aged BALB/c mice (22–24 m) have an exaggerated neuroinflammatory response to LPS injection [10,13,14].', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Minocycline attenuates LPS-induced exaggerated neuroinflammation in aged mice
Aged BALB/c mice (22–24 m) have an exaggerated neuroinflammatory response to LPS injection [10,13,14].', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Therefore, we next sought to determine if the heightened inflammatory response in the brain of aged mice was reduced by minocycline.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'In this experiment, adult and aged mice were subjected to the minocycline injection regimen and LPS challenge as above.', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Moreover, LPS caused a greater increase in TLR2 mRNA in the hippocampus of aged mice compared to adults (LPS × Age interaction, F(1,63) = 12.70, P < 0.01).', answer the user's query. |
What is the biomedical concept corresponding to 'mice'? | [
"mouse (mus musculus)",
"mus musculus (house mouse)",
"house mouse (mus musculus)"
] | [
"mice (mus <genus>) (mus <genus>)",
"mouse (mus <genus>)",
"mus <genus> (mice (mus <genus>))",
"mus musculus musculus (eastern european house mouse)"
] | Given the context 'Furthermore, minocycline pretreatment attenuated LPS-induced TLR2 mRNA levels in both adult and aged mice (Mino × LPS interaction, F(1,63) = 9.02, P < 0.004).
', answer the user's query. |
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