id stringlengths 7 10 | title stringlengths 8 354 | content stringlengths 91 4.1k | contents stringlengths 164 4.24k | embedding listlengths 384 384 |
|---|---|---|---|---|
PMID:21849 | Opsonic requirements for phagocytosis of Streptococcus pneumoniae types VI, XVIII, XXIII, and XXV. | An assay system employing radiolabeled, heat-killed Streptococcus pneumoniae and human polymorphonuclear leukocytes was utilized to study serum pneumococcal opsonic requirements. Comparing the kinetics of phagocytosis in normal serum, heat-inactivated serum, immunoglobulin G (IgG)-deficient serum, C2-deficient serum, a... | Opsonic requirements for phagocytosis of Streptococcus pneumoniae types VI, XVIII, XXIII, and XXV. An assay system employing radiolabeled, heat-killed Streptococcus pneumoniae and human polymorphonuclear leukocytes was utilized to study serum pneumococcal opsonic requirements. Comparing the kinetics of phagocytosis in ... | [
-0.05509427562355995,
-0.00355360796675086,
-0.047772206366062164,
-0.03283281996846199,
0.008942889980971813,
0.012579252012073994,
0.044813282787799835,
0.07679922878742218,
-0.05946570262312889,
0.017748938873410225,
0.02236478216946125,
-0.09894466400146484,
-0.0031645642593503,
0.0079... |
PMID:21850 | Rabbit intestinal fluid stimulation by an enterotoxigenic factor of Staphylococcus aureus. | An exoprotein of Staphylococcus aureus 100 that elicited a positive ileal loop response in the rabbit model was investigated in this study. The protein, as it occurred in the culture supernatant fluid, could be detected initially in the late log phase of growth under aerobic and anaerobic conditions. It was stable unde... | Rabbit intestinal fluid stimulation by an enterotoxigenic factor of Staphylococcus aureus. An exoprotein of Staphylococcus aureus 100 that elicited a positive ileal loop response in the rabbit model was investigated in this study. The protein, as it occurred in the culture supernatant fluid, could be detected initially... | [
-0.07318134605884552,
-0.025763042271137238,
0.006423612590879202,
-0.024792324751615524,
0.055633705109357834,
-0.05195189267396927,
0.044697534292936325,
0.0630514994263649,
-0.04412855952978134,
0.021992001682519913,
-0.013219960033893585,
-0.06616752594709396,
0.006862352602183819,
0.0... |
PMID:21851 | Factors affecting germination of Trichophyton mentagrophytes arthrospores. | Nutritional and environmental factors affecting germination of Trichophyton mentagrophytes arthrospores were investigated. Germination of dormant arthrospores occurred only in rich complex media such as Sabouraud dextrose broth or vitamin-free Casamino Acids. However, once activated, arthrospores were able to germinate... | Factors affecting germination of Trichophyton mentagrophytes arthrospores. Nutritional and environmental factors affecting germination of Trichophyton mentagrophytes arthrospores were investigated. Germination of dormant arthrospores occurred only in rich complex media such as Sabouraud dextrose broth or vitamin-free C... | [
0.02284899912774563,
0.0037923045456409454,
0.007026515901088715,
0.0240927767008543,
0.05072836950421333,
-0.04510911554098129,
-0.0176906306296587,
0.014995355159044266,
-0.12920889258384705,
-0.03311919793486595,
0.022237280383706093,
-0.08717460185289383,
0.023644015192985535,
0.004681... |
PMID:21852 | International aspects of oral microbiology. | It appears that the bacteria of the mouth are remarkably similar throughout the world. There are differences, but they are mostly of a quantitative rather than a qualitative nature. Although much is yet to be learned on the regulation of the oral ecosystems, these quantitative fluctuations to a large extent seem to be ... | International aspects of oral microbiology. It appears that the bacteria of the mouth are remarkably similar throughout the world. There are differences, but they are mostly of a quantitative rather than a qualitative nature. Although much is yet to be learned on the regulation of the oral ecosystems, these quantitativ... | [
0.015456468798220158,
-0.015056617558002472,
-0.003531428286805749,
0.001262022415176034,
0.04190139099955559,
-0.03887635096907616,
0.00528015336021781,
0.025820162147283554,
-0.00007738242857158184,
-0.022141721099615097,
-0.035911597311496735,
-0.11354652047157288,
0.038717083632946014,
... |
PMID:21853 | Classification and determination of cerebral biovailability of psychotropic drugs by quantitative "pharmaco-EEG" and psychometric investigations (studies with AX-A411-BS). | Utilizing computerized quantitative analysis of the human scalp recorded electroencephalogram (EEG), it is possible to classify psychotropic drugs. While neuroleptic compounds produce an increase of slow and decrease of fast activities, anxiolytic substances induce an augmentation of fast waves, decrease of alpha waves... | Classification and determination of cerebral biovailability of psychotropic drugs by quantitative "pharmaco-EEG" and psychometric investigations (studies with AX-A411-BS). Utilizing computerized quantitative analysis of the human scalp recorded electroencephalogram (EEG), it is possible to classify psychotropic drugs. ... | [
-0.04545389488339424,
0.01957148313522339,
-0.012981249019503593,
-0.022437917068600655,
-0.013516753911972046,
0.03747925907373428,
0.08625001460313797,
-0.013849974609911442,
-0.0028362625744193792,
-0.042230214923620224,
0.006363962311297655,
0.014504938386380672,
-0.018351612612605095,
... |
PMID:21854 | On the distribution of drugs in saliva and blood plasma. | The equilibration of drug concentrations between blood plasma (unbound part) and saliva was studied for selected drugs with different physicochemical properties: Quinidine, sulfamerazine, paracetamol, diazepam and ethanol. From these and other experimental results it is suggested: 1. The concentration ratio between sal... | On the distribution of drugs in saliva and blood plasma. The equilibration of drug concentrations between blood plasma (unbound part) and saliva was studied for selected drugs with different physicochemical properties: Quinidine, sulfamerazine, paracetamol, diazepam and ethanol. From these and other experimental result... | [
-0.0328265056014061,
0.010874313302338123,
0.022724177688360214,
-0.018142251297831535,
-0.018761446699500084,
0.01369556039571762,
0.09351415932178497,
0.03795301914215088,
-0.02552475407719612,
-0.028015458956360817,
-0.03889122232794762,
-0.023697666823863983,
0.0035597800742834806,
0.0... |
PMID:21866 | Consumer survey: an approach to teaching consumer participation in community health. | This consumer survey conducted by senior baccalaureate students in a family and community nursing course developed as a result of student recognition of the need for direct consumer input in identification of community health needs. The format was developed, pretested and revised by faculty. The door-to-door survey was... | Consumer survey: an approach to teaching consumer participation in community health. This consumer survey conducted by senior baccalaureate students in a family and community nursing course developed as a result of student recognition of the need for direct consumer input in identification of community health needs. Th... | [
0.02673848532140255,
0.015234713442623615,
0.004103288520127535,
-0.030415337532758713,
0.023905787616968155,
0.007177911698818207,
0.016986072063446045,
0.06832560896873474,
-0.05786146596074104,
-0.013682344928383827,
-0.02529599703848362,
-0.026166385039687157,
-0.024210242554545403,
-0... |
PMID:21867 | An evalutive study of a nursing center for community health nursing student experiences. | The findings from the evaluation study indicated that nursing students were able to accomplish the community health nursing course objectives through a non-traditional entry point. The study also demonstrated that a School of Nursing can successfully initiate and carry out health care (the service program was also eval... | An evalutive study of a nursing center for community health nursing student experiences. The findings from the evaluation study indicated that nursing students were able to accomplish the community health nursing course objectives through a non-traditional entry point. The study also demonstrated that a School of Nursi... | [
-0.0005716172163374722,
-0.024694327265024185,
0.026601796969771385,
0.007473825477063656,
0.00620997091755271,
-0.019440820440649986,
0.003309966064989567,
0.06155577301979065,
-0.05128420889377594,
-0.03833255544304848,
-0.011766104958951473,
0.014317423105239868,
-0.0020117308013141155,
... |
PMID:21868 | Physiologic measures of nonhuman primates during physical restraint and chemical immobilization. | The arterial acid-base balance and other selected physiologic measures of physically restrained and chemically immobilized nonhuman primates from the families Callithricidae, Cebidae, Cercopithecidae, and Pongidae were compared. The physically restrained primates had significantly lower pH, pCO2, and base excess values... | Physiologic measures of nonhuman primates during physical restraint and chemical immobilization. The arterial acid-base balance and other selected physiologic measures of physically restrained and chemically immobilized nonhuman primates from the families Callithricidae, Cebidae, Cercopithecidae, and Pongidae were comp... | [
-0.020637573674321175,
0.06156795844435692,
0.03337946534156799,
0.03179691731929779,
0.040539465844631195,
-0.01042223908007145,
0.09170498698949814,
0.025032488629221916,
-0.01768448017537594,
0.013380874879658222,
0.03879765793681145,
-0.07718007266521454,
-0.020996160805225372,
0.02323... |
PMID:21872 | Isolation and preliminary characterization of two forms of ribulose 1,5-bisphosphate carboxylase from Rhodopseudomonas capsulata. | The presence of two distinct forms of ribulose 1,5-bisphosphate carboxylase has been demonstrated in extracts of Rhodopseudomonas capsulata, similar to the form I (peak I) and form II (peak II) carboxylases previously described from R. sphaeroides (J. Gibson and F. R. Tabita, J. Biol. Chem 252:943-949, 1977). The two a... | Isolation and preliminary characterization of two forms of ribulose 1,5-bisphosphate carboxylase from Rhodopseudomonas capsulata. The presence of two distinct forms of ribulose 1,5-bisphosphate carboxylase has been demonstrated in extracts of Rhodopseudomonas capsulata, similar to the form I (peak I) and form II (peak ... | [
-0.07661697268486023,
-0.07423733919858932,
0.008406521752476692,
0.0026765456423163414,
-0.011067519895732403,
-0.044151365756988525,
0.04864651709794998,
0.07827180624008179,
-0.11512498557567596,
-0.031743310391902924,
0.059858448803424835,
-0.03027014620602131,
0.014156682416796684,
0.... |
PMID:21873 | Thermodynamics of the electrochemical proton gradient in bovine heart submitochondrial particles. | The electrical and chemical components of the electrochemical proton gradient of submitochondrial particles can be monitored simultaneously by continuously recording optical signals from the probes oxonol-VI and 9-aminoacridine. Either respiration or ATP hydrolysis causes a red shift in the absorption spectrum of oxono... | Thermodynamics of the electrochemical proton gradient in bovine heart submitochondrial particles. The electrical and chemical components of the electrochemical proton gradient of submitochondrial particles can be monitored simultaneously by continuously recording optical signals from the probes oxonol-VI and 9-aminoacr... | [
-0.08491107821464539,
0.01794300228357315,
-0.018106264993548393,
0.07066141068935394,
0.02240023761987686,
-0.044214289635419846,
0.05035337805747986,
-0.01665963977575302,
-0.013862253166735172,
0.019176281988620758,
0.03593556210398674,
-0.10039395093917847,
-0.02510937862098217,
0.0310... |
PMID:21874 | Singlet oxygen as a mediator in the hematoporphyrin-catalyzed photooxidation of NADPH to NADP+ in deuterium oxide. | The oxygen-dependent photooxidation of NADPH in the presence of hematoporphyrin in D2O results in the production of enzymatically active NADP+. The reaction is not inhibited by benzoate, mannitol, superoxide dismutase, or catalase. Moreover, addition of either potassium superoxide or H2O2 does not potentiate the reacti... | Singlet oxygen as a mediator in the hematoporphyrin-catalyzed photooxidation of NADPH to NADP+ in deuterium oxide. The oxygen-dependent photooxidation of NADPH in the presence of hematoporphyrin in D2O results in the production of enzymatically active NADP+. The reaction is not inhibited by benzoate, mannitol, superoxi... | [
-0.09214519709348679,
0.057317644357681274,
-0.04555743560194969,
0.02268112823367119,
0.05069174990057945,
-0.005057310685515404,
0.06625773757696152,
0.030845312401652336,
-0.1019580289721489,
-0.03357673063874245,
0.04259860888123512,
0.0032856250181794167,
0.022801149636507034,
-0.0011... |
PMID:21875 | Metabolism of dog gastric mucosa. Levels of glycolytic, citric acid cycle and other intermediates. | Several metabolites, including those of glycolysis, the citric acid cycle, the hexose monophosphate shunt, glutamate, aspartate, and Coenzyme A were measured in defined parietal cell-enriched freeze-dried sections of dog gastric biopsies derived from nonsecreting and secreting tissue. In addition, NH3, ribulose 5-phosp... | Metabolism of dog gastric mucosa. Levels of glycolytic, citric acid cycle and other intermediates. Several metabolites, including those of glycolysis, the citric acid cycle, the hexose monophosphate shunt, glutamate, aspartate, and Coenzyme A were measured in defined parietal cell-enriched freeze-dried sections of dog ... | [
-0.028759531676769257,
-0.043116431683301926,
0.026689628139138222,
0.04578394442796707,
0.02222689613699913,
-0.018045393750071526,
0.030459970235824585,
-0.021675312891602516,
-0.007997269742190838,
-0.024340033531188965,
0.02018721029162407,
-0.13737107813358307,
-0.0326012559235096,
0.... |
PMID:21877 | Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae. | An enzyme that hydrolyzes the O-glycosidic linkage between alpha-N-acetyl-D-galactosamine and serine or threonine in mucins and mucin-type glycoproteins was purified by chromatography on an Affi-Gel 202 column or isoelectric focusing from filtrates of Diplococcus pneumoniae cultures. The final preparations were free of... | Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae. An enzyme that hydrolyzes the O-glycosidic linkage between alpha-N-acetyl-D-galactosamine and serine or threonine in mucins and mucin-type glycoproteins was purified by chromatography on an Affi-Gel 202 column or isoe... | [
-0.06801532208919525,
-0.042317088693380356,
-0.02480703592300415,
-0.015628354623913765,
0.024007923901081085,
-0.06115535646677017,
0.006852826103568077,
-0.011729616671800613,
-0.04916101694107056,
-0.053685326129198074,
0.0652075931429863,
-0.11278319358825684,
-0.038413211703300476,
0... |
PMID:21881 | Characterization of human thyroxine-binding globulin. Evidence for a single polypeptide chain. | Thyroxine-binding globulin (TBG) was purified from fresh human plasma by affinity, anion exchange, and gel filtration chromatography. The protein gave a single band in overloaded analytical disc gel electrophoresis. The molecular weight was 54,000 and E1%/1 cm at 280 nm, corrected for thyroxine (T4) absorbance, was 6.1... | Characterization of human thyroxine-binding globulin. Evidence for a single polypeptide chain. Thyroxine-binding globulin (TBG) was purified from fresh human plasma by affinity, anion exchange, and gel filtration chromatography. The protein gave a single band in overloaded analytical disc gel electrophoresis. The molec... | [
-0.07376142591238022,
0.0061878785490989685,
-0.03404320031404495,
-0.03770650923252106,
0.04138529673218727,
0.0060527753084897995,
0.08936876058578491,
-0.010130316950380802,
-0.08537794649600983,
-0.006636525504291058,
0.003216379089280963,
-0.09413937479257584,
0.010135812684893608,
0.... |
PMID:21882 | Structure and stability of human thyroxine-binding globulin. | The secondary and tertiary structure of human plasma thyroxine-binding globulin (TBG) was investigated by circular dichroism and fluorescence properties. The relaxation time of TBG indicated that it is a compact, symmetric molecule. It was calculated from the far ultraviolet CD spectrum that about one-half of the pepti... | Structure and stability of human thyroxine-binding globulin. The secondary and tertiary structure of human plasma thyroxine-binding globulin (TBG) was investigated by circular dichroism and fluorescence properties. The relaxation time of TBG indicated that it is a compact, symmetric molecule. It was calculated from the... | [
-0.08636222779750824,
0.03215101361274719,
0.011465804651379585,
-0.026007210835814476,
0.07203970104455948,
0.03374398499727249,
0.06889370828866959,
-0.007074801251292229,
-0.08580078184604645,
-0.023238608613610268,
0.01009276695549488,
-0.06060584634542465,
0.010779389180243015,
0.0294... |
PMID:21883 | Neurospora crassa glutamine synthetase. Role of enzyme synthesis and degradation on the regulation of enzyme concentration during exponential growth. | The specific activity of Neurospora crassa glutamine synthetase varies according to the nitrogen source in which the organism is grown. In a poor nitrogen source such as glutamate, the specific activity of the enzyme is higher than that found in good nitrogen sources such as ammonium or glutamine. These differences in ... | Neurospora crassa glutamine synthetase. Role of enzyme synthesis and degradation on the regulation of enzyme concentration during exponential growth. The specific activity of Neurospora crassa glutamine synthetase varies according to the nitrogen source in which the organism is grown. In a poor nitrogen source such as ... | [
0.030060525983572006,
0.012648371048271656,
-0.005786677356809378,
0.005410137120634317,
0.003340798430144787,
0.018400954082608223,
0.016277918592095375,
-0.013581227511167526,
-0.06406684219837189,
0.019065309315919876,
-0.010986553505063057,
-0.06276194006204605,
-0.007452281191945076,
... |
PMID:21887 | Studies of the human testis. VIII. Product activation of 17beta-hydroxysteroid oxidoreductase for testosterone. | Cell-free homogenates prepared from human testis tissue were incubated with either 1.3 x 10(-5)M[4-14C]testosterone and 2 x 10(-4)M NADP or 1.3 x 10(-5) [4-14C]nadrostenedione and 2 x 10(-4)M NADPH. Addition of non-radioactive androstenedione and testosterone to the incubation medium increased the formation of [14C]and... | Studies of the human testis. VIII. Product activation of 17beta-hydroxysteroid oxidoreductase for testosterone. Cell-free homogenates prepared from human testis tissue were incubated with either 1.3 x 10(-5)M[4-14C]testosterone and 2 x 10(-4)M NADP or 1.3 x 10(-5) [4-14C]nadrostenedione and 2 x 10(-4)M NADPH. Addition ... | [
-0.0011766571551561356,
0.054475683718919754,
-0.008639827370643616,
-0.013785295188426971,
0.027139244601130486,
0.011632579378783703,
0.020243946462869644,
0.021116048097610474,
-0.02502259612083435,
-0.06503045558929443,
0.033030759543180466,
-0.07917407900094986,
0.035082731395959854,
... |
PMID:21888 | Rapid measurement of an index of testosterone binding to serum binding globulin using ion exchange columns. | DEAE cellulose "mini" columns at pH 7.4 retain testosterone (T) bound to testosterone binding globulin (TeBG), which can be eluted at pH 2. Small 1:2 diluted serum or plasma samples are incubated with a tracer dose of tritiated T in pH 7.4 Tris buffer at 37 C then chilled and placed on columns at 4 C. Free and albumin ... | Rapid measurement of an index of testosterone binding to serum binding globulin using ion exchange columns. DEAE cellulose "mini" columns at pH 7.4 retain testosterone (T) bound to testosterone binding globulin (TeBG), which can be eluted at pH 2. Small 1:2 diluted serum or plasma samples are incubated with a tracer do... | [
-0.040935613214969635,
0.09319497644901276,
0.02092927135527134,
-0.030440451577305794,
0.02643340267241001,
-0.013742279261350632,
0.0916537269949913,
0.03709644079208374,
-0.02987516112625599,
-0.012706735171377659,
0.01224259939044714,
-0.10075871646404266,
0.023978445678949356,
0.05060... |
PMID:21889 | Identification of Neisseria by electron capture gas-liquid chromatography of metabolites in a chemically defined growth medium. | A dual-purpose study was carried out in an attempt to develop a rapid, sensitive method to identify Neisseria species by gas chromatography and to learn more about the metabolism of these organisms. Sixty-nine isolates of Neisseria were grown in a chemically defined fluid medium; the spent medium was extracted sequenti... | Identification of Neisseria by electron capture gas-liquid chromatography of metabolites in a chemically defined growth medium. A dual-purpose study was carried out in an attempt to develop a rapid, sensitive method to identify Neisseria species by gas chromatography and to learn more about the metabolism of these orga... | [
-0.02714049629867077,
0.07001590728759766,
-0.0219078678637743,
0.031015219166874886,
0.05026404187083244,
0.0026873284950852394,
-0.007037500850856304,
-0.014902177266776562,
-0.08908472955226898,
-0.001090059638954699,
0.02334982343018055,
-0.08533740043640137,
-0.009361221455037594,
0.0... |
PMID:21890 | Auditory word discrimination in male children diagnosed as having minimal brain dysfunction. | Investigated auditory word discrimination skill in children diagnosed as having minimal brain dysfunction (MBD), a heretofore unexplored topic in the study of MBD. A lack of auditory discrimination skill seems relevant to learning deficiency in language acquisition, a typical sign of MBD. The present study tested the h... | Auditory word discrimination in male children diagnosed as having minimal brain dysfunction. Investigated auditory word discrimination skill in children diagnosed as having minimal brain dysfunction (MBD), a heretofore unexplored topic in the study of MBD. A lack of auditory discrimination skill seems relevant to learn... | [
0.0035496556665748358,
-0.006663263309746981,
-0.009427524171769619,
-0.011028978042304516,
-0.014608610421419144,
0.045313842594623566,
0.05446069687604904,
0.026731472462415695,
-0.028973408043384552,
-0.01977301388978958,
0.02550363726913929,
-0.047864675521850586,
0.03793839365243912,
... |
PMID:21891 | Patient characteristics and expectancy measures as factors that influence the expectancy-improvement relationship. | A recent study found factored measures of patient's expectancies for therapeutic gain significantly correlated with 1 of 15 objective measures of treatment outcome for the hospitalized patients. A subsequent study of the same relationship that used unfactored expectancy measured with a diagnostically homogenous sample ... | Patient characteristics and expectancy measures as factors that influence the expectancy-improvement relationship. A recent study found factored measures of patient's expectancies for therapeutic gain significantly correlated with 1 of 15 objective measures of treatment outcome for the hospitalized patients. A subseque... | [
0.017713919281959534,
0.019257351756095886,
0.05586518719792366,
0.005747989285737276,
-0.000813826103694737,
-0.030015312135219574,
0.047907184809446335,
0.060766492038965225,
0.025568433105945587,
-0.013423270545899868,
0.021651634946465492,
0.006834149826318026,
0.025188636034727097,
0.... |
PMID:21892 | An application of actuarial methods in psychiatric diagnosis. | An actuarial program for psychiatric diagnosis is evaluated for agreement with final clinical diagnosis in a series of 288 patients. The acturial program provides a probability differential diagnosis based on an analysis of history and background data, symptom rating profiles, and MMPI clinical scale profiles. The obse... | An application of actuarial methods in psychiatric diagnosis. An actuarial program for psychiatric diagnosis is evaluated for agreement with final clinical diagnosis in a series of 288 patients. The acturial program provides a probability differential diagnosis based on an analysis of history and background data, sympt... | [
-0.06183725222945213,
0.02657351829111576,
0.050606466829776764,
-0.007011878304183483,
0.03590018302202225,
0.0635727122426033,
0.05099763348698616,
0.03560741990804672,
0.003873350564390421,
-0.04233661666512489,
0.031054722145199776,
0.030480554327368736,
-0.017095474526286125,
-0.02473... |
PMID:21893 | Pretty patient - healthy patient? A study of physical attractiveness and psychopathology. | Recent research has shown that physically attractive persons are viewed by others, and by themselves, as "better" in many ways than less attractive persons. The trend in research findings is pervasive, and a stereotype has been proposed: "what is beautiful is good." This study explored the relationship between physical... | Pretty patient - healthy patient? A study of physical attractiveness and psychopathology. Recent research has shown that physically attractive persons are viewed by others, and by themselves, as "better" in many ways than less attractive persons. The trend in research findings is pervasive, and a stereotype has been pr... | [
-0.003389838384464383,
0.0035624627489596605,
0.039134345948696136,
0.02732911892235279,
0.011752324178814888,
0.0046571590937674046,
0.08164320141077042,
0.017426328733563423,
-0.006422071252018213,
-0.021924631670117378,
0.04323134943842888,
-0.020885635167360306,
-0.0076614245772361755,
... |
PMID:21898 | Chronic eosinophilic pneumonia followed by polyarteritis nodosa complicating the course of bronchial asthma. Report of a case. | The syndrome of pulmonary infiltrates with eosinophilia (PIE) occurs rarely in the asthmatic patient. An unusual case is presented in which progressive bronchoconstriction and exaggerated blood eosinophilia preceded the recognition of two seemingly unrelated diseases, each of which can independently result in hypereosi... | Chronic eosinophilic pneumonia followed by polyarteritis nodosa complicating the course of bronchial asthma. Report of a case. The syndrome of pulmonary infiltrates with eosinophilia (PIE) occurs rarely in the asthmatic patient. An unusual case is presented in which progressive bronchoconstriction and exaggerated blood... | [
-0.01661754585802555,
0.002651410410180688,
0.03352592512965202,
0.0458795465528965,
-0.06920471042394638,
-0.028994880616664886,
0.07456503063440323,
0.026284657418727875,
-0.03324073553085327,
-0.001054469496011734,
-0.013616452924907207,
-0.018989579752087593,
0.038012485951185226,
0.00... |
PMID:21899 | Tardive dyskinesia in psychogeriatric patients: a five-year follow-up. | The neurologic side effects of antipsychotic drugs in the treatment of major psychiatric disorders are causing great concern. The status of tardive dyskinesia in 13 elderly psychiatric patients at the 5-year follow-up point, is reported. In 11 of the 13, tardive dyskinesia persisted. tamong these 11 patients, the sever... | Tardive dyskinesia in psychogeriatric patients: a five-year follow-up. The neurologic side effects of antipsychotic drugs in the treatment of major psychiatric disorders are causing great concern. The status of tardive dyskinesia in 13 elderly psychiatric patients at the 5-year follow-up point, is reported. In 11 of th... | [
-0.03753175958991051,
0.018453890457749367,
0.026224961504340172,
0.025267472490668297,
-0.0531461276113987,
0.04910840839147568,
0.050524115562438965,
0.020124781876802444,
-0.036375742405653,
-0.05173874273896217,
-0.0010883513605222106,
0.00950184091925621,
0.00947166234254837,
0.061119... |
PMID:21931 | A prospective analysis interstitial pneumonia and opportunistic viral infection among recipients of allogeneic bone marrow grafts. | A prospective study of 80 bone marrow transplant recipients with acute leukemia and aplastic anemia employed serial viral cultures, determination of complement-fixing antibody to cytomegalovirus (CMV), and study of material obtained from open lung biopsy and autopsy. There were 43 episodes of interstitial pneumonia, 28... | A prospective analysis interstitial pneumonia and opportunistic viral infection among recipients of allogeneic bone marrow grafts. A prospective study of 80 bone marrow transplant recipients with acute leukemia and aplastic anemia employed serial viral cultures, determination of complement-fixing antibody to cytomegalo... | [
-0.02803707867860794,
0.040585462003946304,
-0.04144890978932381,
0.018000677227973938,
0.015713907778263092,
-0.01812109537422657,
0.0440836176276207,
0.07716881483793259,
-0.025704683735966682,
0.012271310202777386,
0.02228565141558647,
-0.038690630346536636,
-0.04645627364516258,
-0.044... |
PMID:21932 | pH as an indicator of free fatty acid release from adipocytes. | A convenient method of measuring initial rates of free fatty acid efflux from isolated adipocytes during triglyceride breakdown by hormone-sensitive lipase is described. The procedure is based on the dissociation of protons from carboxyl groups of free fatty acids. A recording pH meter is used to monitor H+ concentrati... | pH as an indicator of free fatty acid release from adipocytes. A convenient method of measuring initial rates of free fatty acid efflux from isolated adipocytes during triglyceride breakdown by hormone-sensitive lipase is described. The procedure is based on the dissociation of protons from carboxyl groups of free fatt... | [
-0.020848611369729042,
0.018488816916942596,
0.007418069057166576,
0.04907715320587158,
0.006838119123131037,
-0.04858420044183731,
0.022144095972180367,
0.04764100909233093,
-0.035131651908159256,
-0.022189687937498093,
0.07012473791837692,
-0.07944013178348541,
-0.013711812905967236,
0.0... |
PMID:21933 | Type I Escherichia coli pili: characterization of binding to monkey kidney cells. | We have demonstrated binding of purified pili from a strain of Escherichia coli to Vero cell monolayers as a model of prokaryotic-eukaryotic cell adherence. Pili bound to the tissue culture in a rapid reaction that did not require enzymatic activation. Attachment occurred optimally at pH 4-5 and could be inhibited by a... | Type I Escherichia coli pili: characterization of binding to monkey kidney cells. We have demonstrated binding of purified pili from a strain of Escherichia coli to Vero cell monolayers as a model of prokaryotic-eukaryotic cell adherence. Pili bound to the tissue culture in a rapid reaction that did not require enzymat... | [
-0.08480601012706757,
-0.03176860511302948,
-0.006317416206002235,
-0.03295355290174484,
0.021064234897494316,
-0.048602472990751266,
0.09784483909606934,
0.06479845196008682,
-0.023267677053809166,
0.023478815332055092,
0.003983729984611273,
-0.04196634516119957,
0.02652822621166706,
0.01... |
PMID:21934 | Isolation of pH-optima and apparent Michaelis constants of highly purified enzymes from human and animal sources. Comparison of enzymes of human and animal origin, I. | Enzymes from animal sources are frequently used for quality control of enzyme activity determination in clinical chemistry. For this purpose they should be very similar to human enzymes. It is shown that preparations of enzymes of diagnostic interest from human and porcine organs, purified in exactly the same way, have... | Isolation of pH-optima and apparent Michaelis constants of highly purified enzymes from human and animal sources. Comparison of enzymes of human and animal origin, I. Enzymes from animal sources are frequently used for quality control of enzyme activity determination in clinical chemistry. For this purpose they should ... | [
-0.03990193456411362,
0.003756977152079344,
-0.02093883417546749,
0.056335363537073135,
0.005768916569650173,
-0.04826413840055466,
0.08762440085411072,
0.07457232475280762,
0.01611533761024475,
0.02383260242640972,
0.014816842041909695,
-0.05569291487336159,
-0.04655221849679947,
0.035015... |
PMID:21935 | A nurse practitioner in a family practice residency: role description and impact on continuity of the practitioner-patient relationship. | The nurse practitioner and physician's assistant are new health practitioners providing primary health care. When teamed with family physicians, these new health practitioners can extend patient services. Family physicians should be trained to work with new health practitioners effectively. Presented is a model where a... | A nurse practitioner in a family practice residency: role description and impact on continuity of the practitioner-patient relationship. The nurse practitioner and physician's assistant are new health practitioners providing primary health care. When teamed with family physicians, these new health practitioners can ext... | [
-0.03311554715037346,
0.012196015566587448,
0.01497156172990799,
-0.020178107544779778,
0.021365230903029442,
0.007672121748328209,
0.05739136040210724,
-0.007867906242609024,
-0.04218815267086029,
-0.05744566768407822,
0.02389766089618206,
0.01225205883383751,
-0.018465910106897354,
-0.00... |
PMID:21936 | Regulation of the bacterial microflora of the vagina in cyclic female rats. | The bacterial microflora was examined in the vagina of cyclic female rats kept under normal laboratory conditions. Large variations occurred during the cycle with high numbers of bacteria (10(5)-10(8) per vagina) during proestrus and estrus and low numbers (10(1)-10(4) per vagina) during the diestrus period. Histologic... | Regulation of the bacterial microflora of the vagina in cyclic female rats. The bacterial microflora was examined in the vagina of cyclic female rats kept under normal laboratory conditions. Large variations occurred during the cycle with high numbers of bacteria (10(5)-10(8) per vagina) during proestrus and estrus and... | [
0.024066762998700142,
-0.015419511124491692,
0.014997538179159164,
0.03178810328245163,
0.038602400571107864,
-0.01275111548602581,
0.017494792118668556,
0.05190254747867584,
0.0023593450896441936,
-0.019391726702451706,
-0.011485103517770767,
-0.0773724615573883,
0.03130214661359787,
0.01... |
PMID:21937 | Effects of neurotransmitters upon the discharge of secretory product from the cutaneous glands of the red-spotted newt. | The effects of sympathetic and parasympathetic agonists and antagonists on discharge of secretory product by the granular and mucous glands were examined in the red-spotted newt, Notopthalmus viridescens viridescens. Observations were made also on the South African clawed toad. Xenopus laevis, the grass frog, Rana pipi... | Effects of neurotransmitters upon the discharge of secretory product from the cutaneous glands of the red-spotted newt. The effects of sympathetic and parasympathetic agonists and antagonists on discharge of secretory product by the granular and mucous glands were examined in the red-spotted newt, Notopthalmus viridesc... | [
-0.00954829715192318,
-0.016856957226991653,
0.033788688480854034,
0.04689627140760422,
-0.03497045859694481,
-0.01709415577352047,
0.0994730144739151,
0.028932753950357437,
-0.023755522444844246,
-0.0168038047850132,
-0.013282859697937965,
-0.04844586178660393,
0.027862414717674255,
0.048... |
PMID:21938 | Glutamate dehydrogenases from tissues of the ribbed mussel Modiolus demissus: ADP activation and possible physiological significance. | Glutamate dehydrogenase (E.C. 14.1.3) was localized in the mitochondria from heart, gill, mantle and hepatopancreas of this euryhaline bivalve mollusc. Activity levels were low (0.1-0.4 mumoles/min/g wet weight) in all tissues when assayed in the glutamate forming direction. Partially purified gill mitochondrial GDH wa... | Glutamate dehydrogenases from tissues of the ribbed mussel Modiolus demissus: ADP activation and possible physiological significance. Glutamate dehydrogenase (E.C. 14.1.3) was localized in the mitochondria from heart, gill, mantle and hepatopancreas of this euryhaline bivalve mollusc. Activity levels were low (0.1-0.4 ... | [
0.002648771507665515,
-0.028640244156122208,
-0.0118044288828969,
0.0037954305298626423,
0.016860369592905045,
-0.008080531843006611,
0.02110554650425911,
0.014331938698887825,
-0.04469037055969238,
-0.027816712856292725,
0.057567011564970016,
-0.1333046853542328,
0.0013595265336334705,
0.... |
PMID:21939 | On the induction of zoosporogenesis in the rumen phycomycetes Neocallimastix frontalis, Piromonas communis and Sphaeromonas communis. | The plant components inducing zoosporogenesis in the rumen phycomycetes Neocallimastix frontalis, Sphaeromonas communis and Piromonas communis were widely distributed in the plant kingdom with no apparent taxonomic relationship. In Lolium perenne L. (perennial rye-grass) and Hordeum distichon (barley), the components w... | On the induction of zoosporogenesis in the rumen phycomycetes Neocallimastix frontalis, Piromonas communis and Sphaeromonas communis. The plant components inducing zoosporogenesis in the rumen phycomycetes Neocallimastix frontalis, Sphaeromonas communis and Piromonas communis were widely distributed in the plant kingdo... | [
0.020623547956347466,
0.003632519394159317,
0.05419810861349106,
0.022642601281404495,
0.0938870832324028,
-0.04611640423536301,
-0.031472645699977875,
0.04494503512978554,
-0.006563747767359018,
0.005987623240798712,
-0.010120127350091934,
-0.0925358310341835,
0.0012596264714375138,
0.003... |
PMID:21940 | Studies on the mechanism of action of oxygen-labile haemolysins. | The sensitivities of the binding step and the lytic step of haemolysis by pneumolysin to the action of various inhibitors and to variations in the assay conditions were studied. Binding was inhibited by HgCl2 and N-ethylmaleimide. Lysis by previously fixed lysin was insensitive to HgCl2 and only slightly sensitive to N... | Studies on the mechanism of action of oxygen-labile haemolysins. The sensitivities of the binding step and the lytic step of haemolysis by pneumolysin to the action of various inhibitors and to variations in the assay conditions were studied. Binding was inhibited by HgCl2 and N-ethylmaleimide. Lysis by previously fixe... | [
-0.08040020614862442,
0.025376807898283005,
-0.08289913833141327,
-0.0048421588726341724,
0.022719591856002808,
-0.019935639575123787,
0.038903653621673584,
-0.0035220582503825426,
-0.02829340472817421,
0.011093758046627045,
-0.012949435971677303,
-0.03216642886400223,
-0.008252514526247978,... |
PMID:21941 | The enzymic interconversion of acetate and acetyl-coenzyme A in Escherichia coli. | Mutants of Escherichia coli K12 have been isolated that grow on media containing pyruvate of proline as sole carbon sources despite the presence of 10 or 50 mM-sodium fluoroacetate. Such mutants lack either acetate kinase [ATP: acetate phosphotransferase; EC 2.7.2.1] or phosphotransacetylase [acetyl-CoA: orthophosphate... | The enzymic interconversion of acetate and acetyl-coenzyme A in Escherichia coli. Mutants of Escherichia coli K12 have been isolated that grow on media containing pyruvate of proline as sole carbon sources despite the presence of 10 or 50 mM-sodium fluoroacetate. Such mutants lack either acetate kinase [ATP: acetate ph... | [
-0.05315360799431801,
-0.005557880736887455,
-0.07793290913105011,
0.04483306407928467,
-0.007218223996460438,
-0.04447363689541817,
-0.0009567030938342214,
-0.0006538981688208878,
-0.058587536215782166,
0.011240433901548386,
0.052460938692092896,
-0.11606068164110184,
0.02288227528333664,
... |
PMID:21942 | Adsorption of a phage tail-like bacteriocin to isolated lipopolysaccharide of Rhizobium. | Purified lipopolysaccharide (LPS) from the bacteriocin sensitive strain Rhizobium lupini i6-2 was shown to neutralize the killing activity of the bacteriocin. In the electron microscopical preparation the phage tail-like bacteriocin appears to be adsorbed to the LPS; the tail sheath is contracted and the fibres are ori... | Adsorption of a phage tail-like bacteriocin to isolated lipopolysaccharide of Rhizobium. Purified lipopolysaccharide (LPS) from the bacteriocin sensitive strain Rhizobium lupini i6-2 was shown to neutralize the killing activity of the bacteriocin. In the electron microscopical preparation the phage tail-like bacterioci... | [
-0.08420803397893906,
0.0065132430754601955,
-0.08862458914518356,
0.027596935629844666,
0.006824185140430927,
-0.06574112176895142,
0.03878696635365486,
0.034372515976428986,
-0.02488364651799202,
-0.045651163905858994,
0.043984875082969666,
-0.061026860028505325,
0.06707590818405151,
-0.... |
PMID:21943 | Alertness and clear thinking as characteristics of high naturally occurring autonomic nervous system arousal. | Studies of the effect of induced mood on the autonomic nervous system (ANS) suggested that naturally occurring mood might also covary with the ANS. Ss were 13 men and women aged 20 to 70. Fatigue, confusion, and depression were measured on the Profile of Mood States, while barometric pressure and the ANS indices of hea... | Alertness and clear thinking as characteristics of high naturally occurring autonomic nervous system arousal. Studies of the effect of induced mood on the autonomic nervous system (ANS) suggested that naturally occurring mood might also covary with the ANS. Ss were 13 men and women aged 20 to 70. Fatigue, confusion, an... | [
0.013606532476842403,
0.04412471130490303,
0.010872592218220234,
0.05118400231003761,
-0.005094993859529495,
0.027754098176956177,
0.09705615043640137,
-0.0008128625340759754,
0.02030227705836296,
-0.06679408997297287,
-0.03315972536802292,
-0.022582609206438065,
0.017076149582862854,
0.08... |
PMID:21944 | Effects of denervation on the neuraminidase activity of slow and fast muscles of rabbits. | The presence in skeletal muscles of rabbits of neuraminidase activity on sialyl lactose was demonstrated. By comparing the specific activity of this enzyme in different control muscles, it was shown that it was 2.3 times higher in the slow than in the fast muscles. Seven days after denervation, we observed a significan... | Effects of denervation on the neuraminidase activity of slow and fast muscles of rabbits. The presence in skeletal muscles of rabbits of neuraminidase activity on sialyl lactose was demonstrated. By comparing the specific activity of this enzyme in different control muscles, it was shown that it was 2.3 times higher in... | [
-0.05196505784988403,
-0.055931005626916885,
0.03037935681641102,
0.021060343831777573,
0.027935242280364037,
-0.021928302943706512,
0.06676485389471054,
0.040692657232284546,
0.011956539005041122,
-0.05390278995037079,
-0.01497107744216919,
-0.05358506739139557,
0.00852268934249878,
0.058... |
PMID:21945 | Influence of zinc deficiency on retinal reductase and oxidase activities in rat liver and testes. | The influence of zinc deficiency on vitamin A metabolism in rats was investigated by assessing two specific enzymes involved in its metabolism viz retinal reductase and retinal oxidase in the liver as well as in the testes. The activity of retinal reductase in the liver was not altered in zinc deficiency. Retinal oxida... | Influence of zinc deficiency on retinal reductase and oxidase activities in rat liver and testes. The influence of zinc deficiency on vitamin A metabolism in rats was investigated by assessing two specific enzymes involved in its metabolism viz retinal reductase and retinal oxidase in the liver as well as in the testes... | [
-0.0019702960271388292,
0.06276769936084747,
-0.01684851385653019,
0.03782762214541435,
0.01994323916733265,
-0.0025134808383882046,
0.023734597489237785,
0.06801652908325195,
-0.07356201857328415,
-0.008634365163743496,
0.02254898101091385,
-0.0665065199136734,
0.03572229668498039,
0.0373... |
PMID:21948 | Oxidation kinetics of phenothiazine and 10-methylphenothiazine in acidic medium. | The rate of phenothiazine degradation in an acidic oxygen-saturated medium was studied. 3H-Phenothiazine-3-one and phenothiazine 5-oxide are produced by parallel reactions, and 7-(10'-phenothiazinyl)-3H-phenothiazine-3-one is produced in a more complex manner. The overall phenothiazine degradation rate appears to be pH... | Oxidation kinetics of phenothiazine and 10-methylphenothiazine in acidic medium. The rate of phenothiazine degradation in an acidic oxygen-saturated medium was studied. 3H-Phenothiazine-3-one and phenothiazine 5-oxide are produced by parallel reactions, and 7-(10'-phenothiazinyl)-3H-phenothiazine-3-one is produced in a... | [
-0.10653514415025711,
0.06620348244905472,
-0.04593167081475258,
0.025066686794161797,
-0.02853659726679325,
0.01708899810910225,
0.020809542387723923,
-0.010708336718380451,
-0.02120278775691986,
-0.020725684240460396,
0.021101584658026695,
-0.038291506469249725,
0.07767854630947113,
0.06... |
PMID:21949 | Mechanism for phenothiazine oxidation. | The mechanism of phenothiazine degradation was studied by following the degradation of 3,10'-diphenothiazine in ethanol-water mixtures as well as the electrochemical oxidation of phenothiazine. A mechanism, including the formation of an oxidized dimer and some polymers, is suggested. | Mechanism for phenothiazine oxidation. The mechanism of phenothiazine degradation was studied by following the degradation of 3,10'-diphenothiazine in ethanol-water mixtures as well as the electrochemical oxidation of phenothiazine. A mechanism, including the formation of an oxidized dimer and some polymers, is suggest... | [
-0.09309177845716476,
0.06005246937274933,
-0.049582116305828094,
0.027125278487801552,
-0.020076662302017212,
-0.016384391114115715,
0.038492292165756226,
0.01399924699217081,
-0.030235782265663147,
-0.023707935586571693,
0.01053920853883028,
-0.005170817021280527,
0.05760626867413521,
0.... |
PMID:21950 | Synthesis, physicochemical properties, and antitumor activities of analogs of 1-phenyl-3-benzyl-3-methyltriazenes. | To study the effect of substituents on the antitumor activities of analogs of 1-phenyl-3-benzyl-3-methyltriazenes, a series of compounds was designed and synthesized in which the substituent on the 1-phenyl was an electron-withdrawing group and the substituent on the 3-benzyl had a broad range of physicochemical proper... | Synthesis, physicochemical properties, and antitumor activities of analogs of 1-phenyl-3-benzyl-3-methyltriazenes. To study the effect of substituents on the antitumor activities of analogs of 1-phenyl-3-benzyl-3-methyltriazenes, a series of compounds was designed and synthesized in which the substituent on the 1-pheny... | [
-0.04798201099038124,
-0.050120338797569275,
-0.05730046331882477,
0.0031728369649499655,
0.012383134104311466,
-0.01726086251437664,
0.022990213707089424,
-0.009076764807105064,
-0.05126723274588585,
-0.02831941656768322,
-0.002929634414613247,
-0.02233564294874668,
0.052861589938402176,
... |
PMID:21951 | Biopharmaceutic factors that influence effects of anticholinergic drugs: comparison of propantheline, hexocyclium, and isopropamide. | The antisecretory (determined from salivary flow rates) and antimotility (determined from riboflavin absorption) effects of usually recommended doses of propantheline, hexocyclium, and isopropamide were compared in four adult volunteers. Both propantheline and hexocyclium significantly decreased salivary flow and incre... | Biopharmaceutic factors that influence effects of anticholinergic drugs: comparison of propantheline, hexocyclium, and isopropamide. The antisecretory (determined from salivary flow rates) and antimotility (determined from riboflavin absorption) effects of usually recommended doses of propantheline, hexocyclium, and is... | [
-0.03470532223582268,
0.0032022781670093536,
0.01805647648870945,
0.0065941885113716125,
0.011684412136673927,
0.01199541799724102,
0.05611515790224075,
0.07756619900465012,
-0.09011771529912949,
-0.07075642794370651,
0.01176061388105154,
0.019575046375393867,
0.02259235829114914,
-0.02109... |
PMID:21952 | Nature of acid-induced fluorescence of 17alpha-methyltestosterone. | The fluorescence of the 17alpha-methyltestosterone-trichloroacetic acid reaction product, 1,2,10,15,16,17-hexahydro-10,17,17-trimethylcyclopenta[alpha]phenanthren-3-one, in strong acid was investigated. Structural requirements for fluorescence were derived from absorption and fluorescence studies of related phenanthren... | Nature of acid-induced fluorescence of 17alpha-methyltestosterone. The fluorescence of the 17alpha-methyltestosterone-trichloroacetic acid reaction product, 1,2,10,15,16,17-hexahydro-10,17,17-trimethylcyclopenta[alpha]phenanthren-3-one, in strong acid was investigated. Structural requirements for fluorescence were deri... | [
-0.008692135103046894,
0.02746223844587803,
-0.02557944692671299,
0.022503536194562912,
0.04601085186004639,
-0.023553013801574707,
0.016266169026494026,
0.024715078994631767,
-0.011729755438864231,
-0.07177545130252838,
0.012959975749254227,
-0.098142609000206,
0.023111537098884583,
-0.00... |
PMID:21953 | Indolizine derivativatives with biological activity III: 3-(3-Aminopropyl)-2-methylindolizine, 3-(3-Aminopropyl)-2-methyl-5,6,7,8-tetrahydroindolizine, and their N -alkyl derivatives. | The syntheses and a preliminary pharmacological evaluation of some aminopropylindolizines and aminopropyltetrahydroindolizines are reported. All compounds showed anti-5-hydroxytryptamine, anti-histamine, and antiacetylcholine activities. Some also exhibited weak CNS activity. | Indolizine derivativatives with biological activity III: 3-(3-Aminopropyl)-2-methylindolizine, 3-(3-Aminopropyl)-2-methyl-5,6,7,8-tetrahydroindolizine, and their N -alkyl derivatives. The syntheses and a preliminary pharmacological evaluation of some aminopropylindolizines and aminopropyltetrahydroindolizines are repor... | [
-0.05705961212515831,
-0.01054021529853344,
-0.022943051531910896,
0.00012546198558993638,
-0.04548681527376175,
-0.007954873144626617,
0.05927134305238724,
0.029117971658706665,
-0.033195219933986664,
-0.02695298381149769,
0.04353608563542366,
0.011948780156672001,
0.003743339329957962,
-... |
PMID:21954 | Fluorescence properties of glafenine. | The fluorescence properties of glafenine are partly caused by the anthranilic acid nucleus of the molecule. Correlations are made between fluorescence capacities and UV absorbance. Analytical determinations can be carried out in different solvents, e.g., ether, benzene, and ethanol. Linearity of the emission intensity ... | Fluorescence properties of glafenine. The fluorescence properties of glafenine are partly caused by the anthranilic acid nucleus of the molecule. Correlations are made between fluorescence capacities and UV absorbance. Analytical determinations can be carried out in different solvents, e.g., ether, benzene, and ethanol... | [
0.027905592694878578,
-0.0016429118113592267,
-0.017934195697307587,
0.007551803719252348,
0.029754795134067535,
-0.022092299535870552,
0.07401418685913086,
0.03161946311593056,
-0.07182095944881439,
-0.07029355317354202,
0.0009297492215409875,
-0.027659384533762932,
0.002395111136138439,
... |
PMID:21957 | Effects of 4-aminopyridine at the frog neuromuscular junction. | Micromolar concentrations of 4-aminopyridine (4-AP) were able to increase the amplitude of the end-plate current in frog neuromuscular junction blocked either by d-tubocurarine or by low Ca++ high Mg++ medium. The end-plate potential was also increased. These effects were reversible. The changes in the end-plate curren... | Effects of 4-aminopyridine at the frog neuromuscular junction. Micromolar concentrations of 4-aminopyridine (4-AP) were able to increase the amplitude of the end-plate current in frog neuromuscular junction blocked either by d-tubocurarine or by low Ca++ high Mg++ medium. The end-plate potential was also increased. The... | [
-0.06621900200843811,
-0.01598891243338585,
0.05053940787911415,
0.03626898303627968,
-0.04509342089295387,
0.007084827870130539,
0.049438636749982834,
0.03317489102482796,
-0.019556522369384766,
-0.052191440016031265,
0.024074893444776535,
-0.027635205537080765,
0.01296477671712637,
0.055... |
PMID:21958 | Pharmacologic studies on W10,294A, a new bronchodilator. | W10,294A (1,2,3,4-tetrahydro-8,9-dimethoxy-3(2-piperidinoethyl)-5H-[1] benzopyrano [3,4-c] pyridin-5-one dihydrochloride) is a potent antagonist of the bronchoconstriction induced by histamine, methacholine or acetylcholine. In vitro evaluation on guinea pig trachea indicated that W10,294A had both direct smooth muscle... | Pharmacologic studies on W10,294A, a new bronchodilator. W10,294A (1,2,3,4-tetrahydro-8,9-dimethoxy-3(2-piperidinoethyl)-5H-[1] benzopyrano [3,4-c] pyridin-5-one dihydrochloride) is a potent antagonist of the bronchoconstriction induced by histamine, methacholine or acetylcholine. In vitro evaluation on guinea pig trac... | [
-0.053028590977191925,
-0.018739543855190277,
-0.030507542192935944,
0.001995943021029234,
-0.008989972062408924,
-0.008945941925048828,
0.027641864493489265,
0.05264349281787872,
-0.06493675708770752,
-0.023537566885352135,
-0.016721894964575768,
-0.02991841360926628,
-0.05263971909880638,
... |
PMID:21962 | Combining therapeutic approaches. | It would seem on the surface that psychotherapeutic approaches as different as psychoanalysis and behavioral therapy have little in common. In fact, they seem to be similar in terms of expectation of help, nonconfirming experiences, informational learning, changes in self-concept, reinforcement/influence, paradox, and ... | Combining therapeutic approaches. It would seem on the surface that psychotherapeutic approaches as different as psychoanalysis and behavioral therapy have little in common. In fact, they seem to be similar in terms of expectation of help, nonconfirming experiences, informational learning, changes in self-concept, rein... | [
-0.008503810502588749,
0.05003105103969574,
0.023775417357683182,
0.02768130414187908,
-0.02489733137190342,
-0.009594368748366833,
0.0573754608631134,
0.020228397101163864,
0.03064829111099243,
-0.10640145093202591,
0.07675741612911224,
-0.013116404414176941,
0.008958944119513035,
0.04811... |
PMID:21963 | Orally active esters of cephalosporin antibiotics. Synthesis and biological properties of acyloxymethyl esters of 7-(D-2-amino-2-phenylacetamido)-3-[5-methyl-(1,3,4-thiadiazol-2-yl)thiomethyl]-3-cephem-4-carboxylic acid. | The synthesis of the acetoxymethyl (AOM), pivaloloxymethyl (POM), and phthalidyl (PHTH) esters of 7-[D-(-)-2-amino-2-phenylacetamido]-3-[5-methyl-(1,3,4-thiadiazol-2-yl)thiomethyl]-3-cephem-4-carboxylic acid (1a), a broad-spectrum semisynthetic cephalosporin antibiotic, is described. These esters were examined as poten... | Orally active esters of cephalosporin antibiotics. Synthesis and biological properties of acyloxymethyl esters of 7-(D-2-amino-2-phenylacetamido)-3-[5-methyl-(1,3,4-thiadiazol-2-yl)thiomethyl]-3-cephem-4-carboxylic acid. The synthesis of the acetoxymethyl (AOM), pivaloloxymethyl (POM), and phthalidyl (PHTH) esters of 7... | [
-0.04903533309698105,
0.002003683475777507,
-0.00239375326782465,
0.03075810708105564,
0.03109772689640522,
0.012929121032357216,
-0.011918351985514164,
0.06366664171218872,
-0.08438126742839813,
-0.015620690770447254,
0.024750707671046257,
-0.03324032202363014,
0.0632716566324234,
-0.0504... |
PMID:21964 | Some practical results of the London Medical Group conference on iatrogenic disease. | Although many conferences stimulate a great deal of discussion and practical interest at the time, not so many are followed up to try and estimate what, if any, practical results followed the meeting. This the authors of this study have done. (In Britain the 'medical groups' are voluntary groupings of students at medic... | Some practical results of the London Medical Group conference on iatrogenic disease. Although many conferences stimulate a great deal of discussion and practical interest at the time, not so many are followed up to try and estimate what, if any, practical results followed the meeting. This the authors of this study hav... | [
-0.01616223342716694,
0.036791786551475525,
0.012919511646032333,
-0.015512155368924141,
0.058506499975919724,
-0.010891309939324856,
0.024837804958224297,
0.03436668589711189,
-0.02385600283741951,
-0.03050634264945984,
0.011364874430000782,
-0.02058376371860504,
0.021619655191898346,
-0.... |
PMID:21966 | Glucose-6-phosphate dehydrogenase (G6PD) activity of human sperm. | Sperm from normal human donors and a G6PD-A- individual were examined for x-linked glucose-6-phosphate dehydrogenase activity and autosomally linked 6-phosphogluconate dehydrogenase activity. With the use of fluorescence microscopy, we divised a procedure to visualise in individual sperm cells the fluorescence of reduc... | Glucose-6-phosphate dehydrogenase (G6PD) activity of human sperm. Sperm from normal human donors and a G6PD-A- individual were examined for x-linked glucose-6-phosphate dehydrogenase activity and autosomally linked 6-phosphogluconate dehydrogenase activity. With the use of fluorescence microscopy, we divised a procedur... | [
0.027656706050038338,
0.047734010964632034,
0.0017025943379849195,
-0.029858412221074104,
0.0066113825887441635,
0.03210442513227463,
0.04075467959046364,
0.02550445683300495,
-0.023089779540896416,
-0.024015258997678757,
0.03371983394026756,
-0.047892868518829346,
-0.042890820652246475,
-... |
PMID:21967 | Primary care education trends in U.S. medical schools and teaching hospitals. | In 1973 Schroeder and colleagues conducted a survey of U.S. Medical schools in order to ascertain the nature of change in primary care education which had occurred by that date. In 1976 the authors of the present paper utilized the same survey instrument to document trend data over the three-year period. While conclusi... | Primary care education trends in U.S. medical schools and teaching hospitals. In 1973 Schroeder and colleagues conducted a survey of U.S. Medical schools in order to ascertain the nature of change in primary care education which had occurred by that date. In 1976 the authors of the present paper utilized the same surve... | [
0.00920427031815052,
0.03973275050520897,
-0.03729156404733658,
-0.0026054377667605877,
0.038754742592573166,
0.05601142346858978,
-0.05598665773868561,
0.009538957849144936,
-0.05655129626393318,
-0.0035862992517650127,
0.07831605523824692,
0.03919126093387604,
-0.028734130784869194,
-0.0... |
PMID:21968 | Orientation effects on microwave-induced hyperthermia and neurochemical correlates. | This paper describes the effect of field orientation on the hyperthermia produced by microwave irradiation. Rats exposed in the E-orientation (long-axis of animal parallel to E-field) to 1600 tmhz radiation become significantly hotter than those exposed in the H-field at the same power density. Norepinephrine and dopam... | Orientation effects on microwave-induced hyperthermia and neurochemical correlates. This paper describes the effect of field orientation on the hyperthermia produced by microwave irradiation. Rats exposed in the E-orientation (long-axis of animal parallel to E-field) to 1600 tmhz radiation become significantly hotter t... | [
0.006299846339970827,
0.0611044317483902,
0.03490833938121796,
0.0345262847840786,
0.04620080068707466,
0.03805169835686684,
0.05870668962597847,
0.02773156203329563,
-0.020485393702983856,
-0.08326095342636108,
-0.004282432608306408,
0.005982354748994112,
-0.0011256692232564092,
0.0400757... |
PMID:21970 | An electron microscopic study of early developmental stages, myogenesis, oogenesis and cnidogenesis in the anthomedusa, Podocoryne carnea M. Sars. | This descriptive electron microscopic study of the blastogenetic medusa development of Podocoryne carnea focuses on the earliest stages of primordium formation, myogenesis, oogenesis and cnidogenesis. The events which take place at the cellular level prior to the formation of stage 1 (Frey, '68), which are characterize... | An electron microscopic study of early developmental stages, myogenesis, oogenesis and cnidogenesis in the anthomedusa, Podocoryne carnea M. Sars. This descriptive electron microscopic study of the blastogenetic medusa development of Podocoryne carnea focuses on the earliest stages of primordium formation, myogenesis, ... | [
-0.03446969762444496,
-0.06695118546485901,
0.01772356778383255,
-0.003521902719512582,
-0.023704947903752327,
-0.004559779539704323,
-0.0005057277157902718,
0.012569915503263474,
-0.020859375596046448,
0.004982316866517067,
0.040146443992853165,
-0.08109183609485626,
0.041605789214372635,
... |
PMID:21972 | Hormonal regulation of testicular descent: experimental and clinical observations. | Hormonal regulation of testicular descent has been investigated. Based on experimental studies using the rat and on a review of clinical material it has been determined that testicular descent is an androgen-mediated event directly under the regulation of pituitary gonadotropin. Furthermore, the active androgenic metab... | Hormonal regulation of testicular descent: experimental and clinical observations. Hormonal regulation of testicular descent has been investigated. Based on experimental studies using the rat and on a review of clinical material it has been determined that testicular descent is an androgen-mediated event directly under... | [
0.018900945782661438,
0.01937020942568779,
-0.016917353495955467,
-0.013957254588603973,
0.009883707389235497,
0.03060242533683777,
0.014573398046195507,
0.04349619150161743,
-0.047119464725255966,
-0.018457919359207153,
-0.012032462283968925,
-0.06227037310600281,
0.05463235080242157,
0.0... |
PMID:21973 | Protective efficacy of pneumococcal polysaccharide vaccines. | Clinical studies of 6- and 12-valent pneumococcal capsular polysaccharide vaccines were carried out in controlled studies among novice gold miners in South Africa. In the studies 1,523 persons received pneumococcal vaccine, and 3,171 were included as controls. In the great majority of subjects given pneumococcal vaccin... | Protective efficacy of pneumococcal polysaccharide vaccines. Clinical studies of 6- and 12-valent pneumococcal capsular polysaccharide vaccines were carried out in controlled studies among novice gold miners in South Africa. In the studies 1,523 persons received pneumococcal vaccine, and 3,171 were included as controls... | [
-0.013351036235690117,
0.034923799335956573,
-0.04351619631052017,
-0.027622856199741364,
0.020631419494748116,
0.025144975632429123,
0.00479859858751297,
0.04986082762479782,
-0.06981703639030457,
0.028240429237484932,
0.012658106163144112,
-0.0941939502954483,
0.007274777628481388,
-0.04... |
PMID:21974 | Management of diabetic patients with low blood pH. | In metabolic acidosis, where blood pH is less than 7.20, loss of respiratory centre response to lowered carbon dioxide content and increased hydrogen ion concentration may result. The use of sodium bicarbonate for management of diabetic ketosis and lactic acidosis has been controversial (Kaye 1975) in the past, but it ... | Management of diabetic patients with low blood pH. In metabolic acidosis, where blood pH is less than 7.20, loss of respiratory centre response to lowered carbon dioxide content and increased hydrogen ion concentration may result. The use of sodium bicarbonate for management of diabetic ketosis and lactic acidosis has ... | [
-0.04906262829899788,
0.05589097738265991,
0.0169990137219429,
0.025554735213518143,
-0.061006829142570496,
0.004562779795378447,
0.05538875609636307,
0.05347795784473419,
-0.0684165358543396,
0.015751371160149574,
0.01310510840266943,
-0.09151464700698853,
-0.040325142443180084,
0.1043009... |
PMID:21981 | Cause of decrease of ethylmorphine N-demethylase activity of lipid peroxidation in microsomes from the rat, guinea pig and rabbit. | There were marked differences among animal species between NADPH-dependent and ascorbic acid-Fe++-dependent lipid peroxidation. In NADPH-dependent lipid peroxidation, this activity occurred to the greatest extent in rats followed by guinea pigs and rabbits and such was much lower in rabbits than in guinea pigs. On the ... | Cause of decrease of ethylmorphine N-demethylase activity of lipid peroxidation in microsomes from the rat, guinea pig and rabbit. There were marked differences among animal species between NADPH-dependent and ascorbic acid-Fe++-dependent lipid peroxidation. In NADPH-dependent lipid peroxidation, this activity occurred... | [
-0.028599372133612633,
0.00328086712397635,
-0.018086453899741173,
0.08819680660963058,
0.020286161452531815,
-0.021238213405013084,
0.007948016747832298,
0.0673188865184784,
-0.03949383273720741,
-0.03193194419145584,
0.02808920107781887,
-0.011837434023618698,
-0.0021212624851614237,
-0.... |
PMID:21982 | Dualist or pseudo-dualist interactions of mepyramine, diphenhydramine and eprozinol with histamine at H1-receptors. | The types of interaction of mepyramine (M), diphenhydramin: (D) and eprozinol (E), with histamine H1-receptors of guinea pig ileal and tracheal smooth muscle, were comparatively studied in vitro. According to the concentrations used, all three substances showed an apparent dualist mechanism of action on both preparatio... | Dualist or pseudo-dualist interactions of mepyramine, diphenhydramine and eprozinol with histamine at H1-receptors. The types of interaction of mepyramine (M), diphenhydramin: (D) and eprozinol (E), with histamine H1-receptors of guinea pig ileal and tracheal smooth muscle, were comparatively studied in vitro. Accordin... | [
-0.06862958520650864,
0.00558006064966321,
-0.000484065298223868,
0.055103179067373276,
-0.032407499849796295,
-0.028562096878886223,
0.09229601174592972,
0.016147460788488388,
-0.06566952168941498,
-0.029534578323364258,
-0.058671411126852036,
-0.053294405341148376,
-0.003969790413975716,
... |
PMID:21983 | Norepinephrine-synthesizing enzymes in brain, adrenals and peripheral sympathetic nerves of spontaneously hypertensive rats. | Dopamine-beta-hydroxylase (DBH) activity in serum, DBH and tyrosine hydroxylase (TH) activities in mesenteric vessels, and DBH and TH activities in locus coeruleus and hypothalamus of brain did not differ significantly between spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKR) at 16 weeks of... | Norepinephrine-synthesizing enzymes in brain, adrenals and peripheral sympathetic nerves of spontaneously hypertensive rats. Dopamine-beta-hydroxylase (DBH) activity in serum, DBH and tyrosine hydroxylase (TH) activities in mesenteric vessels, and DBH and TH activities in locus coeruleus and hypothalamus of brain did n... | [
-0.02673966996371746,
-0.01847958378493786,
-0.030715005472302437,
0.017485573887825012,
-0.025248993188142776,
-0.009503532201051712,
0.06353140622377396,
-0.017633143812417984,
-0.053167928010225296,
-0.07787356525659561,
0.009992585517466068,
-0.025481797754764557,
-0.007966629229485989,
... |
PMID:21992 | The action of antacids on serum gastrin concentrations in man. | The effects of two doses of NaCl and NaHCO3 as well as of Al(OH3) and AlCl3 respectively, on serum gastrin concentrations and intragastric pH were compared in duodenal ulcer patients. Also the effect of one dose of an AlPO4 containing commercial antacid on serum gastrin concentration and intragastric pH was studied in ... | The action of antacids on serum gastrin concentrations in man. The effects of two doses of NaCl and NaHCO3 as well as of Al(OH3) and AlCl3 respectively, on serum gastrin concentrations and intragastric pH were compared in duodenal ulcer patients. Also the effect of one dose of an AlPO4 containing commercial antacid on ... | [
-0.005208464339375496,
0.01675797998905182,
0.009214993566274643,
0.03156743198633194,
0.04650919511914253,
0.009269137866795063,
0.025435075163841248,
0.045981280505657196,
-0.07912266254425049,
-0.09661220014095306,
-0.012918706983327866,
-0.08913830667734146,
-0.009335992857813835,
0.01... |
PMID:21999 | Pleural effusions. | Many different conditions result in the accumulation of pleural fluid. A diagnostic thoracentesis should be performed on all patients with pleural effusion from whom pleural fluid can be easily obtained. Empirically we have found that when the pleural effusion is more than 10 mm thick on the lateral decubitus roentgeno... | Pleural effusions. Many different conditions result in the accumulation of pleural fluid. A diagnostic thoracentesis should be performed on all patients with pleural effusion from whom pleural fluid can be easily obtained. Empirically we have found that when the pleural effusion is more than 10 mm thick on the lateral ... | [
0.02650091052055359,
-0.00397885125130415,
0.06120777502655983,
-0.0349150188267231,
0.02854352444410324,
-0.02606942132115364,
0.03283560276031494,
0.016568847000598907,
-0.015239432454109192,
0.07141102105379105,
-0.021617498248815536,
-0.08762862533330917,
-0.05930516868829727,
-0.00242... |
PMID:21998 | Alterations in tyrosine aminotransferase isoenzymes of liver of rats as a function of age. | The specific activities (units/mg protein) of tyrosine aminotransferase (TAT) and its isoenzymes, cytoplasmic (c-), mitochondrial (m-) and nuclear (n-TAT), of the liver of 6-, 35- and 76-week old male albino rats were determined. The activities of all the isoenzymes are highest at 6 weeks and are significantly lower at... | Alterations in tyrosine aminotransferase isoenzymes of liver of rats as a function of age. The specific activities (units/mg protein) of tyrosine aminotransferase (TAT) and its isoenzymes, cytoplasmic (c-), mitochondrial (m-) and nuclear (n-TAT), of the liver of 6-, 35- and 76-week old male albino rats were determined.... | [
-0.018690839409828186,
0.029608959332108498,
-0.04379573464393616,
-0.004799120593816042,
-0.0011351782595738769,
0.012537174858152866,
0.09556599706411362,
0.02795056626200676,
-0.05424618721008301,
0.004148031584918499,
0.0611792616546154,
-0.05511397868394852,
0.0023880964145064354,
0.0... |
PMID:22033 | Effectors of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase of rat liver. | The lower Vmax of 6PGDH with respect to G6PDH and its higher sensitivity to inhibition by NADPH, suggest the existence of an imbalance between the two dehydrogenases of the pentose phosphate pathway in rat liver. Possible modulators of these activities, particularly in relation with the inhibition by NADPH in physiolog... | Effectors of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase of rat liver. The lower Vmax of 6PGDH with respect to G6PDH and its higher sensitivity to inhibition by NADPH, suggest the existence of an imbalance between the two dehydrogenases of the pentose phosphate pathway in rat liver. Possible ... | [
-0.01783093810081482,
0.003793146926909685,
-0.00010911042045336217,
-0.019660746678709984,
0.031462423503398895,
-0.011090872809290886,
0.06672985851764679,
0.011382881551980972,
-0.10608023405075073,
-0.02895149029791355,
0.0514526441693306,
-0.014966917224228382,
-0.01941523887217045,
0... |
PMID:22034 | Isocitrate dehydrogenase of Tetrahymena pyriformis. | We have studied the isocitrate dehydrogenase of Tetrahymena pyriformis. This enzyme is able to utilize both NAD and NADP, but kinetic studies suggest that the enzymatic activity with NAD is not of physiological signifance. Some of the factors that might regualte the NADP-dependent isocitrate dehydrogenase were also stu... | Isocitrate dehydrogenase of Tetrahymena pyriformis. We have studied the isocitrate dehydrogenase of Tetrahymena pyriformis. This enzyme is able to utilize both NAD and NADP, but kinetic studies suggest that the enzymatic activity with NAD is not of physiological signifance. Some of the factors that might regualte the N... | [
-0.06500840932130814,
0.02239135652780533,
-0.032044488936662674,
0.01968088001012802,
0.03540327027440071,
-0.00848187692463398,
0.04470663517713547,
0.015153287909924984,
-0.09705459326505661,
-0.015765568241477013,
0.03980189189314842,
-0.05249246954917908,
0.026091475039720535,
0.02240... |
PMID:22035 | [The legal status of medical students during practical training in hospitals (author's transl)]. | The most important change in the qualification regulations in force at the present time is the provision for the practical training of medical students, which occurs not only in university hospitals but also in "teaching hospitals" outside the university. The realization of the practical year is problematic according t... | [The legal status of medical students during practical training in hospitals (author's transl)]. The most important change in the qualification regulations in force at the present time is the provision for the practical training of medical students, which occurs not only in university hospitals but also in "teaching ho... | [
-0.02038952149450779,
0.010608476586639881,
-0.035860806703567505,
-0.013141111470758915,
0.06395646929740906,
-0.03935479372739792,
0.016626480966806412,
0.014993849210441113,
-0.02447318099439144,
0.00924189854413271,
0.012370668351650238,
-0.004252969287335873,
-0.069760262966156,
-0.01... |
PMID:22036 | [Hyperergic collagenoses. Clinical aspects, differential diagnosis and therapy (author's transl)]. | On the basis of inpatient and outpatient observations of the longterm course in 44 patients with erythematodes disseminatus, 8 with periarteritis nodosa, 4 with Wegener's granulomatosis, 5 with dermatomyositis, 3 with giant cell arteritis and 9 with scleroderma the pathogenesis, differential diagnosis and therapy of th... | [Hyperergic collagenoses. Clinical aspects, differential diagnosis and therapy (author's transl)]. On the basis of inpatient and outpatient observations of the longterm course in 44 patients with erythematodes disseminatus, 8 with periarteritis nodosa, 4 with Wegener's granulomatosis, 5 with dermatomyositis, 3 with gia... | [
-0.030648482963442802,
-0.012138043530285358,
0.04216351360082626,
0.05498173087835312,
0.009339568205177784,
-0.0707610622048378,
0.014528874307870865,
0.04488104581832886,
-0.00968092679977417,
-0.042833853513002396,
0.028890183195471764,
-0.03644464537501335,
-0.027836136519908905,
0.02... |
PMID:22042 | Factors influencing germ tube production in Candida albicans. | The capacity of Candida albicans to produce germ tubes in a simple medium is analysed as a function of the pH variation, the bacterial supernatant and the addition of differing concentrations of various species of bacteria. | Factors influencing germ tube production in Candida albicans. The capacity of Candida albicans to produce germ tubes in a simple medium is analysed as a function of the pH variation, the bacterial supernatant and the addition of differing concentrations of various species of bacteria. | [
0.056719403713941574,
0.06015472859144211,
0.008723442442715168,
-0.04246639832854271,
-0.00027065808535553515,
0.002928556641563773,
0.0143192820250988,
0.09590969979763031,
-0.07955537736415863,
0.04911685362458229,
-0.06319159269332886,
-0.0820842906832695,
0.027187656611204147,
-0.0100... |
PMID:22043 | Determinations of pH, moisture, carbohydrates and ash of Egyptian buffalo meat. | A total of 128 samples of Egyptian buffalo meat was analysed for its pH value, moisture, carbohydrates and ash contents. Statistical analysis of the data obtained shows significant difference at 0.01 level for moisture in relation to sex and cut (abdomen and thigh, respectively). There is also significant difference at... | Determinations of pH, moisture, carbohydrates and ash of Egyptian buffalo meat. A total of 128 samples of Egyptian buffalo meat was analysed for its pH value, moisture, carbohydrates and ash contents. Statistical analysis of the data obtained shows significant difference at 0.01 level for moisture in relation to sex an... | [
-0.0036965261679142714,
0.09045116603374481,
0.061612240970134735,
0.013837486505508423,
0.030762504786252975,
-0.03989063575863838,
0.07362018525600433,
0.0047035240568220615,
-0.027032427489757538,
0.003436882048845291,
-0.0057623605243861675,
-0.11131506413221359,
-0.02303464710712433,
... |
PMID:22044 | [Alkali treatment of proteins. I. Behavior of sulfhydryl and disulfide groups in alkali-treated beta-lactoglobulin and alpha-lactalbumin]. | The alkali treatment of beta-lactoglobulin and alpha-lactalbumin results in the splitting of disulphide bonds in the protein molecules. When a 0.8-10(4) M beta-lactoglobulin solution in a 0.022 N sodium hydroxide solution (pH = 12) is heated at 90 degrees C for 30 min, 0-4 M disulphide groups, 2.2 M sulfhydryl groups a... | [Alkali treatment of proteins. I. Behavior of sulfhydryl and disulfide groups in alkali-treated beta-lactoglobulin and alpha-lactalbumin]. The alkali treatment of beta-lactoglobulin and alpha-lactalbumin results in the splitting of disulphide bonds in the protein molecules. When a 0.8-10(4) M beta-lactoglobulin solutio... | [
-0.06931865215301514,
0.030665826052427292,
-0.02828565053641796,
-0.005049253813922405,
0.023541325703263283,
-0.052309658378362656,
0.04464039206504822,
-0.004445317666977644,
-0.045543160289525986,
-0.020808080211281776,
-0.01133894082158804,
-0.11416341364383698,
0.02695060521364212,
0... |
PMID:22049 | Neurotransmitter synthesis and uptake by isolated sympathetic neurones in microcultures. | Assays of isolated single sympathetic neurones show that their transmitter functions can be either adrenergic or cholinergic depending on growth conditions. The data suggest that the number of transmitters made by most mature individual neurones is restricted. | Neurotransmitter synthesis and uptake by isolated sympathetic neurones in microcultures. Assays of isolated single sympathetic neurones show that their transmitter functions can be either adrenergic or cholinergic depending on growth conditions. The data suggest that the number of transmitters made by most mature indiv... | [
-0.009448288008570671,
-0.04802742600440979,
-0.0006732288748025894,
0.025159241631627083,
-0.0398588702082634,
-0.0069155823439359665,
0.12246252596378326,
-0.017432404682040215,
-0.03492268919944763,
-0.016282426193356514,
0.012624843046069145,
-0.024824747815728188,
0.01494518294930458,
... |
PMID:22051 | The influence of pH on the excision of UV-photoproducts from HeLa cells. | Excision of pyrimidine dimers with pH decreasing in UV irradiated HeLa cells can be depressed. This depression is independent of the UV dose within the investigated range. The excision capacity of HeLa repair system from absolute amount of excised dimers is shown. | The influence of pH on the excision of UV-photoproducts from HeLa cells. Excision of pyrimidine dimers with pH decreasing in UV irradiated HeLa cells can be depressed. This depression is independent of the UV dose within the investigated range. The excision capacity of HeLa repair system from absolute amount of excised... | [
-0.08908103406429291,
0.04244392365217209,
0.08035846799612045,
0.037233203649520874,
-0.01674719527363777,
0.006025303155183792,
0.03696172311902046,
0.02883635275065899,
-0.03815691918134689,
0.015475026331841946,
0.01038280688226223,
-0.03949300944805145,
-0.0019720352720469236,
0.07474... |
PMID:22053 | Local glucose utilization in acute focal cerebral ischemia: local dysmetabolism and diaschisis. | By means of an autoradiographic technique employing 14C-2-deoxyglucose, abnormalities of local brain glucose utilization were studied 90 minutes following occlusion of the left middle cerebral and common carotid arteries in a series of pentobarbital-anesthetized cats. Sham-insulted control animals exhibited a normal pa... | Local glucose utilization in acute focal cerebral ischemia: local dysmetabolism and diaschisis. By means of an autoradiographic technique employing 14C-2-deoxyglucose, abnormalities of local brain glucose utilization were studied 90 minutes following occlusion of the left middle cerebral and common carotid arteries in ... | [
-0.0224095918238163,
-0.001839292119257152,
-0.04958878457546234,
0.0644073635339737,
-0.009370374493300915,
0.02527683973312378,
0.07150095701217651,
0.04765160009264946,
0.013859671540558338,
-0.025575701147317886,
0.006837373599410057,
-0.0823129266500473,
-0.05014169216156006,
0.058549... |
PMID:22057 | Significance of oscillation frequency in intrapartum fetal monitoring. | Until now, no statistical data have been available on the significance of the frequency of FHR oscillations. In order to evaluate the relation between oscillation frequency and neonatal outcome, the last 30 minutes of 812 FHR records were analyzed with respect to the number of 812 FHR records were analyzed with respect... | Significance of oscillation frequency in intrapartum fetal monitoring. Until now, no statistical data have been available on the significance of the frequency of FHR oscillations. In order to evaluate the relation between oscillation frequency and neonatal outcome, the last 30 minutes of 812 FHR records were analyzed w... | [
0.003978571854531765,
-0.00789608433842659,
-0.03348575904965401,
0.003489913884550333,
0.02473890781402588,
0.013779786415398121,
0.025494515895843506,
0.04469309002161026,
0.021387364715337753,
-0.006191787775605917,
-0.014050894416868687,
-0.05118487775325775,
-0.018300941213965416,
0.0... |
PMID:22058 | Hyaline membrane disease and acidosis at birth in twins. | To test the hypothesis that the increased incidence of hyaline membrane disease in second-born twins is related to acidosis at birth, umbilical arterial [H+] was measured in 26 sets of premature twins. Although overall Twin B had a lower Apgar score than Twin A, there was no difference in their [H+]. If the delivery in... | Hyaline membrane disease and acidosis at birth in twins. To test the hypothesis that the increased incidence of hyaline membrane disease in second-born twins is related to acidosis at birth, umbilical arterial [H+] was measured in 26 sets of premature twins. Although overall Twin B had a lower Apgar score than Twin A, ... | [
-0.030529139563441277,
-0.006525085773319006,
0.002955798525363207,
0.019497182220220566,
-0.04060874134302139,
0.00978665892034769,
0.04221360385417938,
0.05117453634738922,
-0.001935605308972299,
-0.0135060278698802,
0.022173389792442322,
-0.11074161529541016,
0.03071856126189232,
0.0195... |
PMID:22060 | Serotonin-containing neurons: their possible role in pain and analgesia. | Experimental evidence is reviewed showing that brain and spinal cord serotonergic neurons are involved in nociceptive responses, as well as in the analgesic effects of opiate narcotics. This evidence, based on studies employing pharmacological, surgical, electrophysiological, and dietary manipulations of central nervou... | Serotonin-containing neurons: their possible role in pain and analgesia. Experimental evidence is reviewed showing that brain and spinal cord serotonergic neurons are involved in nociceptive responses, as well as in the analgesic effects of opiate narcotics. This evidence, based on studies employing pharmacological, su... | [
0.016787124797701836,
-0.0031237348448485136,
-0.011371858417987823,
-0.009578672237694263,
0.010749534703791142,
0.024297522380948067,
0.10136765986680984,
0.09580988436937332,
0.0075865620747208595,
-0.048414744436740875,
-0.00429659616202116,
-0.0006554856663569808,
-0.0012809897307306528... |
PMID:22063 | Bicarbonate-induced phosphaturia: Dependence upon the magnitude of phosphate reabsorption. | The acute effect of bicarbonate infusion on inorganic phsophate (Pi) reabsorption was determined in thyroparathyroidectomized (TPTX) rats stabilized on a high phsophorus diet. In the normophosphatemic state, bicarbonate did not affect Pi reabsorption significantly. On the other hand, after hyperphosphatemia was induced... | Bicarbonate-induced phosphaturia: Dependence upon the magnitude of phosphate reabsorption. The acute effect of bicarbonate infusion on inorganic phsophate (Pi) reabsorption was determined in thyroparathyroidectomized (TPTX) rats stabilized on a high phsophorus diet. In the normophosphatemic state, bicarbonate did not a... | [
-0.026434866711497307,
-0.00844806432723999,
0.02461664006114006,
0.014101251028478146,
-0.03099486604332924,
-0.06316682696342468,
0.07649707049131393,
0.04147426038980484,
-0.08351187407970428,
-0.03584735468029976,
0.024149812757968903,
-0.11192485690116882,
0.05120735242962837,
0.06529... |
PMID:22069 | Reversible lactic acidosis associated with repeated intravenous infusions of sorbitol and ethanol. | Infusions of fructose or sorbitol are used commonly in parenteral nutrition and may cause lactic acidosis. A case is reported in whom blood lactate concentration was monitored frequently over a 5-day period during intravenous feeding with a sorbitol-ethanol-amino acid mixture. During the first five infusions blood lact... | Reversible lactic acidosis associated with repeated intravenous infusions of sorbitol and ethanol. Infusions of fructose or sorbitol are used commonly in parenteral nutrition and may cause lactic acidosis. A case is reported in whom blood lactate concentration was monitored frequently over a 5-day period during intrave... | [
-0.0010612106416374445,
-0.039231035858392715,
0.030842524021863937,
0.022296657785773277,
-0.01663448102772236,
-0.029336651787161827,
0.05321746692061424,
0.03673463314771652,
-0.06574759632349014,
-0.036829087883234024,
0.007138657383620739,
-0.06437566876411438,
-0.028114138171076775,
... |
PMID:22075 | Unfolding and refolding occur much faster for a proline-free proteins than for most proline-containing proteins. | The kinetics for unfolding and refolding of a parvalbumin (band 5) have been examined as a function of pH near the transition region, using stopped-flow techniques. This protein is rather unusual in that it has no proline residues, and therefore serves as a good example to test the hypothesis that the rate-limiting ste... | Unfolding and refolding occur much faster for a proline-free proteins than for most proline-containing proteins. The kinetics for unfolding and refolding of a parvalbumin (band 5) have been examined as a function of pH near the transition region, using stopped-flow techniques. This protein is rather unusual in that it ... | [
-0.13102124631404877,
-0.027862029150128365,
-0.04604222998023033,
0.00041467093979008496,
0.015519487671554089,
0.01103104930371046,
-0.002238887595012784,
0.014253919012844563,
-0.028002070263028145,
0.007860017009079456,
0.045108258724212646,
-0.0658983513712883,
0.016956457868218422,
0... |
PMID:22076 | Dopaminergic stimulation of cyclic AMP accumulation and parathyroid hormone release from dispersed bovine parathyroid cells. | The effects of dopaminergic agonists and antagonists have been studied in dispersed bovine parathyroid cells. Dopaminergic agonists caused a transient 20- to 40-fold increase in cellular cyclic AMP and a 2- to 3-fold increase in parathyroid hormone release. Dose-response relationships were similar for cyclic AMP accumu... | Dopaminergic stimulation of cyclic AMP accumulation and parathyroid hormone release from dispersed bovine parathyroid cells. The effects of dopaminergic agonists and antagonists have been studied in dispersed bovine parathyroid cells. Dopaminergic agonists caused a transient 20- to 40-fold increase in cellular cyclic A... | [
-0.0001909223065013066,
-0.0023934575729072094,
-0.00955806951969862,
0.0842861458659172,
-0.04971905052661896,
-0.008136782795190811,
0.0344100184738636,
0.05837932601571083,
-0.01375182531774044,
-0.03994709998369217,
0.05167005583643913,
-0.047194868326187134,
0.015932796522974968,
0.06... |
PMID:22074 | [Comparative evaluation of the effect of serotonin, melatonin and methoxytryptamine on the content of biogenic amines in the hypothalamus and gonadotropic hormones in the pituitary gland depending on the periodicity of phases of the estrous cycle in rats]. | This work is experimental and devoted to the study of functional activity of the pineal gland. The influence of the main biologically active substances (serotonin, melatonin, mexamin) produced by the epiphysis, on the hypothalamo-hypophysial structures was studied; results pointed to the significant role played by the ... | [Comparative evaluation of the effect of serotonin, melatonin and methoxytryptamine on the content of biogenic amines in the hypothalamus and gonadotropic hormones in the pituitary gland depending on the periodicity of phases of the estrous cycle in rats]. This work is experimental and devoted to the study of functiona... | [
0.04838983342051506,
0.023793842643499374,
0.0314721055328846,
-0.005819523707032204,
0.029050258919596672,
0.02983124554157257,
0.07989111542701721,
0.0449492521584034,
0.023509666323661804,
-0.02998681180179119,
-0.051550980657339096,
-0.02754104882478714,
0.008119947277009487,
0.0753095... |
PMID:22077 | Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation. | Partially purified soluble rat liver guanylate cyclase [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] was activated by superoxide dismutase (superoxide: superoxide oxidoreductase, EC 1.15.1.1). This activation was prevented with KCN or glutathione, inhibitors of superoxide dismutase. Guanylate cyclase preparations f... | Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation. Partially purified soluble rat liver guanylate cyclase [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] was activated by superoxide dismutase (superoxide: superoxide oxido... | [
-0.036505650728940964,
0.006788841914385557,
-0.04499314725399017,
0.02459201030433178,
0.05532722920179367,
-0.01806124486029148,
-0.014014829881489277,
0.03407447412610054,
-0.03208377957344055,
0.005276442971080542,
0.003802589839324355,
-0.036021627485752106,
0.01394224725663662,
0.028... |
PMID:22078 | Precursor role of arachidonic acid in release of slow reacting substance from rat basophilic leukemia cells. | The release of slow reacting substance (SRS) from rat basophilic leukemia cells (RBL-1) by the ionophore A23187 (5-10 mug/ml) was stimulated 5-fold by arachidonate and inhibited 78% by 5,8,11,14-eicosatetraynoate (an inhibitor of both fatty acid cyclooxygenase and lipoxygenase). Linoleic acid and linolenic acid both in... | Precursor role of arachidonic acid in release of slow reacting substance from rat basophilic leukemia cells. The release of slow reacting substance (SRS) from rat basophilic leukemia cells (RBL-1) by the ionophore A23187 (5-10 mug/ml) was stimulated 5-fold by arachidonate and inhibited 78% by 5,8,11,14-eicosatetraynoat... | [
-0.06420744955539703,
0.008195111528038979,
-0.026165548712015152,
-0.019483022391796112,
-0.020602412521839142,
0.007763515692204237,
0.014995078556239605,
-0.006640291307121515,
-0.0401393324136734,
-0.012328922748565674,
0.07357469201087952,
-0.024865807965397835,
0.06603284180164337,
-... |
PMID:22079 | Human leukocytic pyrogen: purification and development of a radioimmunoassay. | Leukocytic pyrogen is a small endogenous protein that mediates fever. Because of the limitations of bioassays, circulating leukocytic pyrogen has not been demonstrated during fever in humans. The pyrogen was produced in vitro after phagocytosis of staphylococci by blood monocytes. Antibody against the pyrogen was obtai... | Human leukocytic pyrogen: purification and development of a radioimmunoassay. Leukocytic pyrogen is a small endogenous protein that mediates fever. Because of the limitations of bioassays, circulating leukocytic pyrogen has not been demonstrated during fever in humans. The pyrogen was produced in vitro after phagocytos... | [
-0.02219889499247074,
0.0444231815636158,
-0.025590471923351288,
-0.014601124450564384,
0.07822874188423157,
-0.06968121230602264,
0.097606360912323,
0.024838706478476524,
-0.05763625726103783,
0.010707428678870201,
0.0024715005420148373,
-0.0405634269118309,
-0.041428010910749435,
0.03028... |
PMID:22080 | Oxygen intermediates and mixed valence states of cytochrome oxidase: infrared absorption difference spectra of compounds A, B, and C of cytochrome oxidase and oxygen. | A study of the near-infrared absorption spectra of three oxygen compounds of membrane-bound cytochrome oxidase (ferrocytochrome c:oxygen oxidoreductase; EC 1.9.3.1) shows that the formation of compound A (oxycytochrome oxidase) causes no significant infrared absorbance changes at -103 degrees. At -64 degrees, the forma... | Oxygen intermediates and mixed valence states of cytochrome oxidase: infrared absorption difference spectra of compounds A, B, and C of cytochrome oxidase and oxygen. A study of the near-infrared absorption spectra of three oxygen compounds of membrane-bound cytochrome oxidase (ferrocytochrome c:oxygen oxidoreductase; ... | [
-0.07498542219400406,
0.045675601810216904,
-0.03992879390716553,
0.04683622717857361,
0.0344124510884285,
-0.012635554186999798,
0.04407201334834099,
0.017458397895097733,
0.002129307482391596,
-0.00865207053720951,
0.028416426852345467,
-0.038219377398490906,
0.025966722518205643,
0.0322... |
PMID:22084 | Regulation of release from isolated adrenergic secretory vesicles by ATP-mediated changes in transmembrane potential and anion permeability. | Isolated chromaffin granules release their contents when exposed to calcium, magnesium, ATP, and high levels of chloride ions. The mechanism of release is not well-understood, but changes in anion permeability may be involved. We found that another anion, thiocyanate (SCN-), also activated release in a fashion similar ... | Regulation of release from isolated adrenergic secretory vesicles by ATP-mediated changes in transmembrane potential and anion permeability. Isolated chromaffin granules release their contents when exposed to calcium, magnesium, ATP, and high levels of chloride ions. The mechanism of release is not well-understood, but... | [
-0.05495387315750122,
-0.045723963528871536,
0.02307279221713543,
0.018495170399546623,
-0.00611071428284049,
0.010884608142077923,
0.061657581478357315,
-0.012442110106348991,
-0.0460328571498394,
-0.029077136889100075,
0.03645734116435051,
-0.05311098322272301,
-0.007832367904484272,
0.0... |
PMID:22085 | Regulation of the growth and development of sympathetic neurons in vivo. | The superior cervical ganglion (SCG) in the neonatal mouse and rat has been employed as a model system to study the regulation of ontogeny of presynaptic cholinergic nerves and postsynaptic adrenergic neurons. During postnatal development presynaptic choline acetyltransferase (ChAc) activity increases 30- to 40-fold, w... | Regulation of the growth and development of sympathetic neurons in vivo. The superior cervical ganglion (SCG) in the neonatal mouse and rat has been employed as a model system to study the regulation of ontogeny of presynaptic cholinergic nerves and postsynaptic adrenergic neurons. During postnatal development presynap... | [
0.000783877563662827,
-0.014299039728939533,
-0.022891530767083168,
-0.00453545106574893,
-0.04052957892417908,
0.0019534677267074585,
0.06749698519706726,
-0.02326950803399086,
-0.044036515057086945,
-0.053817279636859894,
0.012620889581739902,
-0.07088235765695572,
0.02448943443596363,
0... |
PMID:22086 | Intramembrane particle aggregation in erythrocyte membranes and band 3-lipid recombinants. | The low pH-induced aggregation of intramembrane particles in human erythrocyte membranes was studied in native membranes and in a reconstituted model system. A significant difference in such aggregation was found when samples of freshly prepared ghosts were compared to ghosts receiving pretreatments that removed most o... | Intramembrane particle aggregation in erythrocyte membranes and band 3-lipid recombinants. The low pH-induced aggregation of intramembrane particles in human erythrocyte membranes was studied in native membranes and in a reconstituted model system. A significant difference in such aggregation was found when samples of ... | [
-0.04796161130070686,
-0.0544082447886467,
-0.032957274466753006,
-0.017384672537446022,
0.029192956164479256,
-0.013631210662424564,
0.06160396337509155,
0.03513306379318237,
-0.010682342574000359,
0.0029999467078596354,
-0.000591744901612401,
-0.09059654921293259,
0.01186192873865366,
0.... |
PMID:22087 | The contractile basis of amoeboid movement III. Structure and dynamics of motile extracts and membrane fragments from Dictyostelium discoideum and Amoeba proteus. | Motile extracts from D, discoideum and A. proteus have been characterized in order to compare the structural dynamics and chemical regulation of movement in 2 different types of amoeboid cells. The structural dynamics of both extracts involve the formation of a nonmotile cytoskeleton followed by the contraction of acti... | The contractile basis of amoeboid movement III. Structure and dynamics of motile extracts and membrane fragments from Dictyostelium discoideum and Amoeba proteus. Motile extracts from D, discoideum and A. proteus have been characterized in order to compare the structural dynamics and chemical regulation of movement in ... | [
-0.09353474527597427,
-0.06456965953111649,
0.02693699486553669,
-0.021608848124742508,
-0.017474010586738586,
-0.031589679419994354,
0.04186881333589554,
-0.008537002839148045,
-0.008139370940625668,
0.0024583900813013315,
0.028279270976781845,
-0.08324399590492249,
-0.03828594461083412,
... |
PMID:22091 | Factors affecting the urinary excretion of endogenously formed dimethyltryptamine in normal human subjects. | The hallucinogenic substance N',N'-dimethyltryptamine and its precursor N-methyltryptamine were found in 24-h specimens of urine from 19 normal human subjects; the mean excretion rates were 386 ng 24 h(-1) and 856 ng 24 h(-1) respectively. The urinary excretion of both compounds was unrelated to age, sex, urinary volum... | Factors affecting the urinary excretion of endogenously formed dimethyltryptamine in normal human subjects. The hallucinogenic substance N',N'-dimethyltryptamine and its precursor N-methyltryptamine were found in 24-h specimens of urine from 19 normal human subjects; the mean excretion rates were 386 ng 24 h(-1) and 85... | [
-0.00801798701286316,
0.03497365117073059,
0.033949874341487885,
0.030721934512257576,
-0.00419018417596817,
0.044625647366046906,
0.08583656698465347,
0.021539460867643356,
-0.00644549960270524,
-0.057418759912252426,
-0.012707190588116646,
-0.07015407830476761,
0.019410710781812668,
0.05... |
PMID:22105 | Properties of four temperate bacteriophages active on Clostridium perfringens type A. | Four temperature bacteriophages (designated as PF1, PF2, PF3 and PF4) were isolated from lysogenic strains of Clostridium perfringens type A. On the basis of plaque morphology, pH stability, DNase and RNase resistance, buoyant density, one-step growth parameters and electron microscope phage dimensions, it seems that t... | Properties of four temperate bacteriophages active on Clostridium perfringens type A. Four temperature bacteriophages (designated as PF1, PF2, PF3 and PF4) were isolated from lysogenic strains of Clostridium perfringens type A. On the basis of plaque morphology, pH stability, DNase and RNase resistance, buoyant density... | [
-0.046883441507816315,
-0.019688572734594345,
-0.04766615852713585,
0.04615332931280136,
0.06453455984592438,
-0.041211843490600586,
0.011678013019263744,
0.010428935289382935,
-0.05554962158203125,
-0.017675179988145828,
0.002394935814663768,
-0.12886373698711395,
0.015875913202762604,
-0... |
PMID:22110 | Hemolytic activity of a lipid material obtained from peroxidized microsomes. | Lipid peroxidation was induced in rat liver microsomes by the addition of NADPH. When mixed with red cells in the presence of EDTA, these peroxidized microsomes caused hemolysis. All of the hemolytic activity of peroxidized microsomes could be extracted with lipid solvents and recovered as an aqueous lipid emulsion. | Hemolytic activity of a lipid material obtained from peroxidized microsomes. Lipid peroxidation was induced in rat liver microsomes by the addition of NADPH. When mixed with red cells in the presence of EDTA, these peroxidized microsomes caused hemolysis. All of the hemolytic activity of peroxidized microsomes could be... | [
-0.06476034969091415,
0.02756284736096859,
-0.015595155768096447,
0.012986348010599613,
-0.03968430310487747,
-0.07930280268192291,
0.04161888360977173,
0.02903759852051735,
-0.0453423447906971,
-0.02499043010175228,
-0.004831966478377581,
-0.010809889994561672,
-0.05684652924537659,
0.005... |
PMID:22111 | Fungal proteases and the mammalian kinin system: I. Brinolase-catalyzed kinin formation and S2160 hydrolysis. | Brinolase, a fungal protease advocated for thrombolytic therapy, released kinin peptides from semi-purified kininogens of the human, rabbit, guinea pig, and mouse, and moreover cleaved an arginyl bond of the chromogenic peptide S2160. Its kinetics demonstrated marked differences from the mammalian protease trypsin. Whe... | Fungal proteases and the mammalian kinin system: I. Brinolase-catalyzed kinin formation and S2160 hydrolysis. Brinolase, a fungal protease advocated for thrombolytic therapy, released kinin peptides from semi-purified kininogens of the human, rabbit, guinea pig, and mouse, and moreover cleaved an arginyl bond of the ch... | [
-0.1118851900100708,
-0.03653685003519058,
-0.044172272086143494,
0.02630770578980446,
-0.004351673182100058,
0.0014608604833483696,
0.0012775635113939643,
0.07142334431409836,
0.0036762256640940905,
0.00019666166917886585,
-0.016281038522720337,
-0.0633787289261818,
-0.06852399557828903,
... |
PMID:22112 | III. Covalent coupling of rat liver phenylalanine hydroxylase. | Optimal conditions have been determined for the coupling of rat liver phenylalanine hydroxylase (PheH) to activated CH-Sepharose-4B. When 12 mg of ligand was reacted with 100 mg of matrix, 20% of the initial enzyme activity was covalently bound along with 55% of the protein. The coupled enzyme showed greater thermal s... | III. Covalent coupling of rat liver phenylalanine hydroxylase. Optimal conditions have been determined for the coupling of rat liver phenylalanine hydroxylase (PheH) to activated CH-Sepharose-4B. When 12 mg of ligand was reacted with 100 mg of matrix, 20% of the initial enzyme activity was covalently bound along with ... | [
-0.09131011366844177,
-0.010384056717157364,
-0.06647585332393646,
0.026710428297519684,
-0.012129677459597588,
-0.05783979222178459,
0.030735600739717484,
-0.008335445076227188,
-0.05077540874481201,
-0.014626516960561275,
0.0032914450857788324,
-0.028409911319613457,
-0.0044195763766765594... |
PMID:22113 | [An experimental study on the pathogenesis of the acute pulmonary insufficiency (author's transl)]. | Parameters of the lungs as Compliance PaCO2, PaO2, have been measured in connection with experimental, pathophysiological insults like hematoma, bone marrow intravasation and hemorrhage, in rabbits. Concerning the compliance quotient, a statistically proved decrease was found within the groups, which have had a hematom... | [An experimental study on the pathogenesis of the acute pulmonary insufficiency (author's transl)]. Parameters of the lungs as Compliance PaCO2, PaO2, have been measured in connection with experimental, pathophysiological insults like hematoma, bone marrow intravasation and hemorrhage, in rabbits. Concerning the compli... | [
-0.08291247487068176,
-0.007645911071449518,
-0.036982569843530655,
0.017813997343182564,
0.019438575953245163,
-0.005549951456487179,
0.11288785934448242,
0.035378992557525635,
-0.057271163910627365,
0.01956620067358017,
-0.016394782811403275,
-0.08820462226867676,
-0.010761400684714317,
... |
PMID:22114 | [Calculation of the pH profile in the intercapillary regions of tumour tissues before and after long-term glucose infusion into the blood stream (author's transl)]. | The pH profile in the intercapillary region of tumor tissue is calculated for normal (Case I) and enhanced glucose concentration in blood (Case II) which was increased by a factor of 4 for an extended period of time. The statement used, which takes into account the reduced lactic acid formation in the unsaturated regio... | [Calculation of the pH profile in the intercapillary regions of tumour tissues before and after long-term glucose infusion into the blood stream (author's transl)]. The pH profile in the intercapillary region of tumor tissue is calculated for normal (Case I) and enhanced glucose concentration in blood (Case II) which w... | [
-0.05812283232808113,
-0.044512148946523666,
0.018078243359923363,
0.009229088202118874,
-0.0011972348438575864,
-0.04032442718744278,
0.1064881831407547,
0.016950499266386032,
0.007375250570476055,
-0.025315191596746445,
0.06549037247896194,
-0.09688745439052582,
-0.02309296280145645,
0.0... |
PMID:22115 | Phenylalanine inhibited p-nitrophenyl phosphatase activity in the serum as an indication of intestinal cellular disruption in the horse. | Examination of tissues obtained from thoroughbred horses showed that the 'intestinal' phosphatase activity could be differentiated from other phosphatases by analysis at a pH of 9-5 and inhibition with 15 mM L-phenylalanine. A simple method for the measurement of 'intestinal' phosphatase in heparinised plasma or serum ... | Phenylalanine inhibited p-nitrophenyl phosphatase activity in the serum as an indication of intestinal cellular disruption in the horse. Examination of tissues obtained from thoroughbred horses showed that the 'intestinal' phosphatase activity could be differentiated from other phosphatases by analysis at a pH of 9-5 a... | [
-0.03841540962457657,
0.007231638301163912,
0.028420807793736458,
0.054065655916929245,
-0.021641124039888382,
-0.04845127835869789,
0.08773168176412582,
0.0793427899479866,
-0.007787779904901981,
-0.03684014081954956,
0.026218008249998093,
-0.08561618626117706,
0.02165304869413376,
0.0236... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.