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PMID:22116 | Effects of intraruminal administration of zinc on gastric acid secretion in sheep. | Intraruminal administration of zinc sulphate at 100 and 200 mg Zn/kg bodyweight resulted in central and peripheral effects in sheep. Feed intake was reduced, pH of the duodenal contents elevated and the secretion of acid from isolated pouches of the abomasum doubled. Suggested explanations include a local inhibitory ef... | Effects of intraruminal administration of zinc on gastric acid secretion in sheep. Intraruminal administration of zinc sulphate at 100 and 200 mg Zn/kg bodyweight resulted in central and peripheral effects in sheep. Feed intake was reduced, pH of the duodenal contents elevated and the secretion of acid from isolated po... | [
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PMID:22117 | Blood acid-base state at a variable temperature. A graphical representation. | When blood temperature is changed in closed system ('anaerobic') conditions, plasma pH and PCO2 vary but no titration by external CO2, acid or alkaline equivalents takes place. It is therefore assumed that the overall acid-base state undergoes no fundamental change. This is further justified by the constancy of osmotic... | Blood acid-base state at a variable temperature. A graphical representation. When blood temperature is changed in closed system ('anaerobic') conditions, plasma pH and PCO2 vary but no titration by external CO2, acid or alkaline equivalents takes place. It is therefore assumed that the overall acid-base state undergoes... | [
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PMID:22123 | Hemodynamic effects of two cardioselective beta-adrenoceptive antagonists, metoprolol and H 87/07, in coronary insufficiency. | Nineteen patients with ischemic heart disease were randomized into two groups and received either metoprolol or H 87/07. Heart catheterization was performed, and the groups were studied at rest and during exercise--before and after intravenous drug administration. During work metoprolol gave a statistically significant... | Hemodynamic effects of two cardioselective beta-adrenoceptive antagonists, metoprolol and H 87/07, in coronary insufficiency. Nineteen patients with ischemic heart disease were randomized into two groups and received either metoprolol or H 87/07. Heart catheterization was performed, and the groups were studied at rest ... | [
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PMID:22124 | Diagnosis of symptomatic gastroesophageal reflux by prolonged monitoring of lower esophageal pH. | Lower esophageal pH was continuously monitored for 15 hours in 10 asymptomatic subjects and 27 patients with symptoms of gastroesophageal reflux, and the pH measurements in symptomatic patients were compared with the results of other esophageal investigations. Symptomatic patients had significantly longer periods of re... | Diagnosis of symptomatic gastroesophageal reflux by prolonged monitoring of lower esophageal pH. Lower esophageal pH was continuously monitored for 15 hours in 10 asymptomatic subjects and 27 patients with symptoms of gastroesophageal reflux, and the pH measurements in symptomatic patients were compared with the result... | [
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PMID:22126 | Cigarette smoke activates guanylate cyclase and increases guanosine 3',5'-monophosphate in tissues. | The gaseous phase of cigarette smoke induced a 2- to 36-fold increase in the activity of guanylate cyclase in supernatant and particulate fractions from various rat and bovine tissues over basal activity. The characteristics of this phenomenon paralleled those of the activation of guanylate cyclase by nitric oxide, whi... | Cigarette smoke activates guanylate cyclase and increases guanosine 3',5'-monophosphate in tissues. The gaseous phase of cigarette smoke induced a 2- to 36-fold increase in the activity of guanylate cyclase in supernatant and particulate fractions from various rat and bovine tissues over basal activity. The characteris... | [
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PMID:22127 | Cytidine 3',5'-monophosphate (cyclic CMP) formation in mammalian tissues. | Mammalian tissues possess the capacity to synthesize cytidine 3',5'-monopHosphate (cyclic CMP) via the enzymatic conversion of cytidine 5'-triphosphate to cyclic CMP by cytidylate cyclase. Cyclic CMP formation occurs best in the presence of manganese or iron, at neutral pH, at 37 degrees C, in the absence of detergents... | Cytidine 3',5'-monophosphate (cyclic CMP) formation in mammalian tissues. Mammalian tissues possess the capacity to synthesize cytidine 3',5'-monopHosphate (cyclic CMP) via the enzymatic conversion of cytidine 5'-triphosphate to cyclic CMP by cytidylate cyclase. Cyclic CMP formation occurs best in the presence of manga... | [
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PMID:22128 | [Follow-up study of non-neoplastic Cushing's syndrome followed by paraneoplastic Cushing's syndrome after removal of a malignant pulmonary tumor. Role of the diffuse endocrine system and APUD (amine precursor uptake decarboxylase) cells]. | A 27 year old woman had in 1965, a paraneoplastic Cushing's syndrome was cured by removal of a pulmonary tumour. The case was published in June 1968. After a normal pregnancy, a recurrence of the Cushing's syndrome in 1969 led in 1970 to bilateral total adrenalectomy in two stages. Pathology showed hyperplastic adrenal... | [Follow-up study of non-neoplastic Cushing's syndrome followed by paraneoplastic Cushing's syndrome after removal of a malignant pulmonary tumor. Role of the diffuse endocrine system and APUD (amine precursor uptake decarboxylase) cells]. A 27 year old woman had in 1965, a paraneoplastic Cushing's syndrome was cured by... | [
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PMID:22136 | Quantitative characteristics of the Feyrter (APUD) cells of the neonatal rabbit lung in normoxia and chronic hypoxia. | Our studies show that the apparent number of Feyrter cells in the lung declines during the neonatal period in normoxic rabbits, and that in hypoxic animals a uniformly and significantly lower number of cells occurs as compared with the normoxic rabbits. There is some indication of degranulation of cells in the hypoxic ... | Quantitative characteristics of the Feyrter (APUD) cells of the neonatal rabbit lung in normoxia and chronic hypoxia. Our studies show that the apparent number of Feyrter cells in the lung declines during the neonatal period in normoxic rabbits, and that in hypoxic animals a uniformly and significantly lower number of ... | [
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PMID:22139 | [Local contractility and acidosis in the ischemic myocardium of the dog (author's transl)]. | In open chest dogs up to 8 side branches of the R, circumflexus and descendens were embraced and could selectively be occluded. With a new developed method local myocardial length changes in the ischemic areas, and with H+-sensitive minielectrodes the interstitial H+-activities were measured. All changes which were obs... | [Local contractility and acidosis in the ischemic myocardium of the dog (author's transl)]. In open chest dogs up to 8 side branches of the R, circumflexus and descendens were embraced and could selectively be occluded. With a new developed method local myocardial length changes in the ischemic areas, and with H+-sensi... | [
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PMID:22143 | Teratological study of etoperidone in the rat and rabbit. | Etoperidone was administered to pregnant rats and rabbits during the period of organogenesis. The oral doses were 100 and 300 mg/kg in the rat and 5, 25 and 50 mg/kg in the rabbit. In the rat the dose of 300 mg/kg produced toxic effects on the mother, consisting mainly of behavioural changes and death in some cases; a ... | Teratological study of etoperidone in the rat and rabbit. Etoperidone was administered to pregnant rats and rabbits during the period of organogenesis. The oral doses were 100 and 300 mg/kg in the rat and 5, 25 and 50 mg/kg in the rabbit. In the rat the dose of 300 mg/kg produced toxic effects on the mother, consisting... | [
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PMID:22146 | In vitro biosynthesis of radioactive estradiol-17 beta, 17-glucosiduronate by rhesus monkey liver. | A method for the preparation of radioactive estradiol-17 beta, 17-glucosiduronate by incubating 3H-estradiol with rhesus monkey liver microsomal preparation in the presence of uridine diphosphoglucuronic acid is described. Small but significant amounts of the conjugate were also obtained from the 150,00 pellet and cyto... | In vitro biosynthesis of radioactive estradiol-17 beta, 17-glucosiduronate by rhesus monkey liver. A method for the preparation of radioactive estradiol-17 beta, 17-glucosiduronate by incubating 3H-estradiol with rhesus monkey liver microsomal preparation in the presence of uridine diphosphoglucuronic acid is described... | [
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PMID:22148 | [Content of nicotinamide coenzymes in rat liver under conditions of nicotinamide administration]. | The content of NAD+, NADH, NADP+, NADPH in the liver of normal, fasting rats, those on the low-carbohydrate diet and suffering from alloxan diabetes was studied as affected by nictotinamide. Changes in the NAD+ content, sum of nicotinamide coenzymes, the [NAD+] + [NADP+]/[NADH] +/- [NADPH] and [NAD+] + [NADH] (sum of n... | [Content of nicotinamide coenzymes in rat liver under conditions of nicotinamide administration]. The content of NAD+, NADH, NADP+, NADPH in the liver of normal, fasting rats, those on the low-carbohydrate diet and suffering from alloxan diabetes was studied as affected by nictotinamide. Changes in the NAD+ content, su... | [
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PMID:22149 | [Equilibrium system consisting of soluble forms of fibrin and the specific anticoagulant D fragment of the firbinogen molecule]. | According to the authors' observations, mixtures of fibrin monomer and fibrinogen-derived D fragment are gradually transformed into an equilibrium system when fibrin exists partly in a solid clot form and partly as a soluble material made unclottable by the influence of fragment D. The amount of such a soluble fibrin p... | [Equilibrium system consisting of soluble forms of fibrin and the specific anticoagulant D fragment of the firbinogen molecule]. According to the authors' observations, mixtures of fibrin monomer and fibrinogen-derived D fragment are gradually transformed into an equilibrium system when fibrin exists partly in a solid ... | [
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PMID:22155 | The sedation and anaesthesia of birds and reptiles. | Demand for veterinary care of birds and reptiles is increasing and with it a knowledge of the current methods of restraint and sedation of these classes. Some of the safer and more practical methods are reviewed and commented on in the light of recent results from the Zoological Society of London's veterinary departmen... | The sedation and anaesthesia of birds and reptiles. Demand for veterinary care of birds and reptiles is increasing and with it a knowledge of the current methods of restraint and sedation of these classes. Some of the safer and more practical methods are reviewed and commented on in the light of recent results from the... | [
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PMID:22157 | [Cholinesterase activity of sperm from rams infected with Brucella ovis]. | Studied were the indices of cholinesterase activity of semen taken from 23 normal rams and 23 rams infected with Brucella ovis, the latter being positive by the complement-fixation test and showing a varying deterioration of the semen production. The results obtained were processed biometrically. Established were depen... | [Cholinesterase activity of sperm from rams infected with Brucella ovis]. Studied were the indices of cholinesterase activity of semen taken from 23 normal rams and 23 rams infected with Brucella ovis, the latter being positive by the complement-fixation test and showing a varying deterioration of the semen production.... | [
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PMID:22159 | Development of hemagglutination assays I. Attachment of anti-HBs antibody to stabilized erythrocytes. | Conditions favoring the coupling of antibody to human erythrocytes stabilized by a variety of reagents were studied with the use of antibody to hepatitis B surface antigen. Functional anti-HBs bound to erythrocytes was measured by radioimmune assay using 125 I-HBsAg. The attachment of anti-HBs to aldehyde-stabilized ce... | Development of hemagglutination assays I. Attachment of anti-HBs antibody to stabilized erythrocytes. Conditions favoring the coupling of antibody to human erythrocytes stabilized by a variety of reagents were studied with the use of antibody to hepatitis B surface antigen. Functional anti-HBs bound to erythrocytes was... | [
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PMID:22164 | Lysis of intact yeast cells and isolated cell walls by an inducible enzyme system of Arthrobacter GJM-1. | Bacterium Arthrobacter GJM-1 known in the literature as a good producer of alpha-mannanase was found to accumulate in the culture fluid lytic activities against viable yeast cells during growth on isolated cell walls or beta-glucan fractions of yeast. The accumulation of the lytic activities showed an inducible charact... | Lysis of intact yeast cells and isolated cell walls by an inducible enzyme system of Arthrobacter GJM-1. Bacterium Arthrobacter GJM-1 known in the literature as a good producer of alpha-mannanase was found to accumulate in the culture fluid lytic activities against viable yeast cells during growth on isolated cell wall... | [
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PMID:22167 | [On the problem of dimethylnitrosamine formation from tetracycline-derivatives by nitrosation reaction in acidic medium (author's transl)]. | The hydrochlorides from tetracycline and six tetracycline derivatives -- 7-dimethylamino-6-des-methyl-6-desoxytetracycline [minocycline], 7-chlorotetracycline [chlorotetracycline], 7-chloro-anhydrotetracycline [anhydrochlorotetracycline, 7-chloro-6-desmethyltetracycline [demethylchlorotetracycline], 5-hydroxytetracycli... | [On the problem of dimethylnitrosamine formation from tetracycline-derivatives by nitrosation reaction in acidic medium (author's transl)]. The hydrochlorides from tetracycline and six tetracycline derivatives -- 7-dimethylamino-6-des-methyl-6-desoxytetracycline [minocycline], 7-chlorotetracycline [chlorotetracycline],... | [
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PMID:22168 | On the mechanism of inactivation and ATP-dependent reactivation of rat liver tyrosine aminotransferase. | The mechanism of in vitro inactivation and ATP-dependent rapid reactivation of rat liver tyrosine aminotransferase by a membrane-bound system from rat liver and kidney cortex and the nucleotide specificity of this process was investigated using partially purified tyrosine amino-transferase as a substrate. Adenosine 5'-... | On the mechanism of inactivation and ATP-dependent reactivation of rat liver tyrosine aminotransferase. The mechanism of in vitro inactivation and ATP-dependent rapid reactivation of rat liver tyrosine aminotransferase by a membrane-bound system from rat liver and kidney cortex and the nucleotide specificity of this pr... | [
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PMID:22171 | [Thioacylamides and thioacylureas as inhibitors of photosystem II (author's transl)]. | Thioacylureas and thioacylamides were found to inhibit photosynthetic O2-evolution (Hill-reactions) of "broken chloroplasts", some derivatives approaching an I50 of 10(-5) M. The inhibition site is near photosystem II. The inhibitory effects of the tested derivatives vary in theri pH-dependency between pH 5 and 8. | [Thioacylamides and thioacylureas as inhibitors of photosystem II (author's transl)]. Thioacylureas and thioacylamides were found to inhibit photosynthetic O2-evolution (Hill-reactions) of "broken chloroplasts", some derivatives approaching an I50 of 10(-5) M. The inhibition site is near photosystem II. The inhibitory ... | [
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PMID:22208 | [Researches to the conversion of sorbit into sorbose by Acetobacter suboxydans (author's transl)]. | The production of sorbose by Acetobacter suboxydans (4) is closely related to the concentration of sorbit in the medium. An increasing concentration of sorbit gives rise to the inhibition of cell reproduction; followed by a decrease of sorbose content in the culture medium. The decrease of sorbose yield in concentratio... | [Researches to the conversion of sorbit into sorbose by Acetobacter suboxydans (author's transl)]. The production of sorbose by Acetobacter suboxydans (4) is closely related to the concentration of sorbit in the medium. An increasing concentration of sorbit gives rise to the inhibition of cell reproduction; followed by... | [
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PMID:22209 | Studies on phosphate-solubilizing bacteria in soil and rhizosphere of different plants. I. Occurrence of bacteria, acid producers, and phosphate dissolvers. | Occurrence of bacteria (total), acid producing and phosphate dissolving micro-organisms in soil, rhizosphere, and rizoplane of Egyptian cotton, peas, or maize during their different growth phases was studied. The rhizosphere effects were generally positive and differed according to type of plant, growth phase of each s... | Studies on phosphate-solubilizing bacteria in soil and rhizosphere of different plants. I. Occurrence of bacteria, acid producers, and phosphate dissolvers. Occurrence of bacteria (total), acid producing and phosphate dissolving micro-organisms in soil, rhizosphere, and rizoplane of Egyptian cotton, peas, or maize duri... | [
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PMID:22210 | Studies on phosphate-solubilizing bacteria in soil and rhizosphere of different plants. II. Selection of the most efficient phosphate-dissolvers and their morphological grouping. | Two hundred colonies which showed positive reaction on the plates prepared for the phosphate-dissolving bacteria from control soil rhizosphere soils and rhizoplane samples of maize, peas, or cotton were isolated at random. Fifty isolates were selected as the most efficient isolates according to their capability for inc... | Studies on phosphate-solubilizing bacteria in soil and rhizosphere of different plants. II. Selection of the most efficient phosphate-dissolvers and their morphological grouping. Two hundred colonies which showed positive reaction on the plates prepared for the phosphate-dissolving bacteria from control soil rhizospher... | [
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PMID:22212 | The N4-hydroxycytidine reduction system in toluenized cells of Salmonella typhimurium. | 1. Enzymatic reduction of N4-hydroxycytidine to cytidine in Salmonella typhimurium is highly specific. The reaction occurs only at the nucleoside level. Free base or its 1-methyl analogue is not reduced. 2. The pH optimum shows a broad plateau with a maximum at pH 7.0. The apparent Km value, estimated in the toluene-tr... | The N4-hydroxycytidine reduction system in toluenized cells of Salmonella typhimurium. 1. Enzymatic reduction of N4-hydroxycytidine to cytidine in Salmonella typhimurium is highly specific. The reaction occurs only at the nucleoside level. Free base or its 1-methyl analogue is not reduced. 2. The pH optimum shows a bro... | [
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PMID:22213 | Intrauterine hypoxia -- a phenomenon peculiar to the second twin. | During a 5-year period twin births occurring at the university hospital were investigated for the presence of clinical and biochemical symptoms of intrauterine hypoxia. It appears that intrauterine hypoxia, when detectable, is limited to the second twin. Some factors which may influence the oxygenation of the second tw... | Intrauterine hypoxia -- a phenomenon peculiar to the second twin. During a 5-year period twin births occurring at the university hospital were investigated for the presence of clinical and biochemical symptoms of intrauterine hypoxia. It appears that intrauterine hypoxia, when detectable, is limited to the second twin.... | [
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PMID:22214 | Clinical trial with lorazepam in pre-operative anxiety. | An important part of the pre-operative preparation of a patient consists in the treatment of his anxiety. One hundred eighty-two patients (varying in age from 17 to 80 years) were sedated for surgery with lorazepam. The evening before intervention, each patient received 1 tablet of lorazepam (2.5 mg) and on the day of ... | Clinical trial with lorazepam in pre-operative anxiety. An important part of the pre-operative preparation of a patient consists in the treatment of his anxiety. One hundred eighty-two patients (varying in age from 17 to 80 years) were sedated for surgery with lorazepam. The evening before intervention, each patient re... | [
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PMID:22215 | Enzyme histochemical study on hepatoma--the relation between enzyme activity and histological type. | The activities of gamma-glutamyl transpeptidase (gamma-GTP), alkaline phosphatase (A-p), and leucine aminopeptidase (LAP) were examined in 18 cases of hepatomas. The activity of gamma-GTP was most remarkable in the hepatoma consisting of small to medium-sized tumor cells showing the least atypism. The enzyme activity f... | Enzyme histochemical study on hepatoma--the relation between enzyme activity and histological type. The activities of gamma-glutamyl transpeptidase (gamma-GTP), alkaline phosphatase (A-p), and leucine aminopeptidase (LAP) were examined in 18 cases of hepatomas. The activity of gamma-GTP was most remarkable in the hepat... | [
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PMID:22217 | An improved direct colorimetric method for the quantitative analysis of urinary hippuric acid as an index of toluene exposure. | An improved direct colorimetric method for determining the concentration of urinary hippuric acid as an index of toluene exposure was described. One tenth ml of urine was diluted with 0.4 ml 0.01 M phosphate buffer H 6.9 and mixed with 0.5 ml pyridine. The mixture was layered on 0.2 ml benzenesulfonyl chloride. The rea... | An improved direct colorimetric method for the quantitative analysis of urinary hippuric acid as an index of toluene exposure. An improved direct colorimetric method for determining the concentration of urinary hippuric acid as an index of toluene exposure was described. One tenth ml of urine was diluted with 0.4 ml 0.... | [
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PMID:22219 | Antibacterial effect, plasmid curing activity and chemical structure of some tricyclic compounds. | Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 microgram/ml. The antibacterial compounds deleted at 40-70% frequency the F'lac plasmid of Escherichia coli K12 LE-140. | Antibacterial effect, plasmid curing activity and chemical structure of some tricyclic compounds. Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 microgram/ml. The antibacterial compound... | [
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PMID:22226 | Inhibition of transmitter release from isolated rabbit kidney by bradykinin. | The effect of kallikrein on the release of norepinephrine has been studied in the isolated perfused rabbit kidney. Kallikrein in the perfusion medium caused an inhibition in the rise of the perfusion pressure induced by periarterial stimulation and in the contraction of rabbit aorta superfused by the venous outflow of ... | Inhibition of transmitter release from isolated rabbit kidney by bradykinin. The effect of kallikrein on the release of norepinephrine has been studied in the isolated perfused rabbit kidney. Kallikrein in the perfusion medium caused an inhibition in the rise of the perfusion pressure induced by periarterial stimulatio... | [
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PMID:22228 | Translation by bacterial cells of messenger RNA for interferon of animal origin. | Escherichia coli, strain AB 1157, cells are capable of translating human, mouse, and chicken messenter RNA for interferon with production of interferon of the corresponding specifity. This translation occurs in the presence of serum. The activity of the resulting interferon decreased in parallel to dilution of the orig... | Translation by bacterial cells of messenger RNA for interferon of animal origin. Escherichia coli, strain AB 1157, cells are capable of translating human, mouse, and chicken messenter RNA for interferon with production of interferon of the corresponding specifity. This translation occurs in the presence of serum. The a... | [
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PMID:22229 | Physico-chemical properties of interferon produced by a mixed leukocyte suspension. | Physico-chemical properties of partially purified interferon produced by a mixed culture of human peripheral blood leukocytes following induction with double-stranded RNA extracted from f2 phage infected Escherichia coli were studied. Molecular heterogeneity of the interferon preparation was demonstrated by gel chromat... | Physico-chemical properties of interferon produced by a mixed leukocyte suspension. Physico-chemical properties of partially purified interferon produced by a mixed culture of human peripheral blood leukocytes following induction with double-stranded RNA extracted from f2 phage infected Escherichia coli were studied. M... | [
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PMID:22230 | Effect of amino acid replacement on the stability of the tobacco mosaic virus protein structure. | A comparative polarographic study on the alkaline degradation of tobacco mosaic virus (TMV) strain vulgare and its mutant TMV 483, having histidine instead of glutamine at position 9 in the polypeptide chain, was performed. In the course of alkaline degradation and subsequent incubation in the supporting electrolyte at... | Effect of amino acid replacement on the stability of the tobacco mosaic virus protein structure. A comparative polarographic study on the alkaline degradation of tobacco mosaic virus (TMV) strain vulgare and its mutant TMV 483, having histidine instead of glutamine at position 9 in the polypeptide chain, was performed.... | [
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PMID:22231 | Ultrastructural studies of cell-virus interaction in reptilian cell lines. IV. Effects of chloramphenicol and ethidium bromide on VSW cell mitochondria and associated virions. | Structural effects of chloramphenicol (CAP) and ethidium bromide (EB) on VSW cell mitochondria and intramitochondrial virions (IMV) have been studied on a comparative basis by thin-section electron microscopy. CAP-treated cells show a wide variety of mitochondrial alterations, frequently involving swelling of the organ... | Ultrastructural studies of cell-virus interaction in reptilian cell lines. IV. Effects of chloramphenicol and ethidium bromide on VSW cell mitochondria and associated virions. Structural effects of chloramphenicol (CAP) and ethidium bromide (EB) on VSW cell mitochondria and intramitochondrial virions (IMV) have been st... | [
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PMID:22232 | Genetic characteristics of clones derived from measles virus strain L-16. | The L-16 vaccine strain of measles virus produced in L-41 cell cultures of various size (0.5-0.2 mm in diameter), with clear or opaque centers, thus being genetically heterogeneous by the S and P markes. The clones derived from the L-16 strain differed from it and from each other in a number of genetic properties. Clon... | Genetic characteristics of clones derived from measles virus strain L-16. The L-16 vaccine strain of measles virus produced in L-41 cell cultures of various size (0.5-0.2 mm in diameter), with clear or opaque centers, thus being genetically heterogeneous by the S and P markes. The clones derived from the L-16 strain di... | [
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PMID:22233 | Influenza virus antigens in human leukocytes after oral administration of live tissue culture influenza A monovaccine. | Influenza A virus antigens were detected in leukocytes by immunofluorescence. After intravenous inoculation of the A/Moscow/16/65 (H2N2) vaccine strain to chickens, cytoplasmic antigens of the virus were observed in mononuclear leukocytes from 24 to 72 hours post inoculation (p.i.). The course of antigen detectability ... | Influenza virus antigens in human leukocytes after oral administration of live tissue culture influenza A monovaccine. Influenza A virus antigens were detected in leukocytes by immunofluorescence. After intravenous inoculation of the A/Moscow/16/65 (H2N2) vaccine strain to chickens, cytoplasmic antigens of the virus we... | [
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PMID:22234 | Isolation and preliminary characterization of temperature-sensitive mutants of pseudorabies virus. | Nine ts mutants of pseudorabies virus (PRV) strain BUK were isolated following bromodeoxyuridine (BUdR) or NaNO2 mutagenesis by a selection technique based on a shiftdown from nonpermissive to permissive temperature. This technique is described and its advantages are discussed. The nine ts mutants have been assigned to... | Isolation and preliminary characterization of temperature-sensitive mutants of pseudorabies virus. Nine ts mutants of pseudorabies virus (PRV) strain BUK were isolated following bromodeoxyuridine (BUdR) or NaNO2 mutagenesis by a selection technique based on a shiftdown from nonpermissive to permissive temperature. This... | [
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PMID:22235 | Measurement of antibodies to herpesvirus types 1 and 2 in human sera by microradioimmunoassay. | The binding of 125I-labelled anti-human antibodies against the fc IgG fragment to unlabelled antiviral immunoglobulins in the surface of infected cells was used to quantitate antibodies against herpes simplex virus type (HSV-1) and type 2 (HSV-2) in sera from patients with cervix carcinoma. The microradioimmunoassay te... | Measurement of antibodies to herpesvirus types 1 and 2 in human sera by microradioimmunoassay. The binding of 125I-labelled anti-human antibodies against the fc IgG fragment to unlabelled antiviral immunoglobulins in the surface of infected cells was used to quantitate antibodies against herpes simplex virus type (HSV-... | [
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PMID:22236 | Infectivity of DNA recovered from cells persistently infected with SV5 paramyxovirus. | Infectivity of DNA isolated from L cells chronically infected with SV5 paramyxovirus was demonstrated by inoculation of continuous RH and HEp-2 cells. Infectivity of the DNA was completely abolished by treatment with deoxyribonuclease or by alkaline hydrolysis but did not change after treatment with ribonuclease and sp... | Infectivity of DNA recovered from cells persistently infected with SV5 paramyxovirus. Infectivity of DNA isolated from L cells chronically infected with SV5 paramyxovirus was demonstrated by inoculation of continuous RH and HEp-2 cells. Infectivity of the DNA was completely abolished by treatment with deoxyribonuclease... | [
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PMID:22237 | Mononuclear cells in Japanese encephalitis virus infection: changes in cells counts and specific fluorescence. | Progressive reduction in blood cell counts was observed in mice inoculated intracerebrally (ic) with Japanese encephalitis (JE) virus. No changes were observed in the blood cell counts of mice inoculated intraperitoneally (ip). Reduction in cell counts after a transient rise was noticed in lymph nodes of mice inoculate... | Mononuclear cells in Japanese encephalitis virus infection: changes in cells counts and specific fluorescence. Progressive reduction in blood cell counts was observed in mice inoculated intracerebrally (ic) with Japanese encephalitis (JE) virus. No changes were observed in the blood cell counts of mice inoculated intra... | [
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PMID:22238 | Search for correlates of resistance to virulent challenge in mice immunized with Coxiella burnetii. | Mice immunized with live phase I or phase II Coxiella burnetii, with killed phase I or phase II organisms or with trichloroacetic acid (TCAE) or phenol (PE) extracts were resistant to intraperitoneal infection with phase I C. burnetii irrespective of whether or not they displayed phase I antibody response at the time o... | Search for correlates of resistance to virulent challenge in mice immunized with Coxiella burnetii. Mice immunized with live phase I or phase II Coxiella burnetii, with killed phase I or phase II organisms or with trichloroacetic acid (TCAE) or phenol (PE) extracts were resistant to intraperitoneal infection with phase... | [
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PMID:22239 | Massive occurrence of rickettsiae of the spotted fever group in fowl tampan, Argas persicus, in the Armenian S.S.R. | Fowl tampans (Argas persicus) collected in Oktemberyan in the Armenian S.S.R. in 1974 were found to be massively infected with rickettsiae of the spotted fever (SF) group. One isolated rickettsial strain, designated Armenia 9, is antigenically related to, and probably identical with, strain Armenia 11 and strain B of R... | Massive occurrence of rickettsiae of the spotted fever group in fowl tampan, Argas persicus, in the Armenian S.S.R. Fowl tampans (Argas persicus) collected in Oktemberyan in the Armenian S.S.R. in 1974 were found to be massively infected with rickettsiae of the spotted fever (SF) group. One isolated rickettsial strain,... | [
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PMID:22240 | Some biological properties of an endotoxic lipopolysaccharide from the typhus group rickettsiae. | A lipophilic thermostable lipopolysaccharide (LPS) complex was isolated by phenol extraction from purified suspensions of the typhus group rickettsiae. The LPS complex is antigenic and possesses some endotoxic properties such as toxicity for actinomycin D-treated mice, pyrogenicity for rabbits and guinea pigs, ability ... | Some biological properties of an endotoxic lipopolysaccharide from the typhus group rickettsiae. A lipophilic thermostable lipopolysaccharide (LPS) complex was isolated by phenol extraction from purified suspensions of the typhus group rickettsiae. The LPS complex is antigenic and possesses some endotoxic properties su... | [
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PMID:22243 | Effects of ethanol on electrical parameters of the in vivo rat stomach. | The gastric transmural electrical potential difference (PD) and direct-current resistance were measured in the rat in vivo under conditions in which the luminal pH was controlled over the pH range 1.0 to 12.0. Raising the pH above 11.0 caused a reduction in both PD and resistance. This is consistent with basic groups l... | Effects of ethanol on electrical parameters of the in vivo rat stomach. The gastric transmural electrical potential difference (PD) and direct-current resistance were measured in the rat in vivo under conditions in which the luminal pH was controlled over the pH range 1.0 to 12.0. Raising the pH above 11.0 caused a red... | [
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PMID:22244 | Gastric mucosal damage by taurine and glycine conjugates of chenodeoxycholic acid. | Bile damage to gastric mucosa may be demonstrated by means of changes in the transmucosal movement of H+ and Na+ ions. In the present study pure 10 mM solutions of taurine and glycine conjugates of chenodeoxycholic acid were instilled into canine Heidenhain pouches. Solutions were prepared at pH 2, 4, and 8, as previou... | Gastric mucosal damage by taurine and glycine conjugates of chenodeoxycholic acid. Bile damage to gastric mucosa may be demonstrated by means of changes in the transmucosal movement of H+ and Na+ ions. In the present study pure 10 mM solutions of taurine and glycine conjugates of chenodeoxycholic acid were instilled in... | [
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PMID:22246 | Endocrine cells of bronchial and bronchiolar epithelium. | Among the epithelial elements of the pulmonary airways are cells with features suggestive of endocrine function. Although these cells share a number of properties with the intestinal endocrine (argentaffine) cells, peptide hormones analogous to the multitude of those present in the gastrointestinal tract have yet to be... | Endocrine cells of bronchial and bronchiolar epithelium. Among the epithelial elements of the pulmonary airways are cells with features suggestive of endocrine function. Although these cells share a number of properties with the intestinal endocrine (argentaffine) cells, peptide hormones analogous to the multitude of t... | [
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PMID:22247 | Fetal reacting bradycardia. | Acute and abrupt fetal bradycardia are considered to be vagal in origin. In addition to head compression and funis compression bradycardias, we will report on those acute fetal bradycardias occurring during maternal seizures and maternal voiding, during aortocaval compression, during terminal labor, and during the imme... | Fetal reacting bradycardia. Acute and abrupt fetal bradycardia are considered to be vagal in origin. In addition to head compression and funis compression bradycardias, we will report on those acute fetal bradycardias occurring during maternal seizures and maternal voiding, during aortocaval compression, during termina... | [
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PMID:22248 | Intrapartum fetal asphyxia: clinical characteristics, diagnosis, and significance in relation to pattern of development. | The clinical and fetal heart rates and acid-base characteristics and their sequelae have been reviewed in 587 patients. The relevant clinical factors in the asphyxia group were the preterm fetus, the intrauterine growth retarded fetus, maternal toxemia, and midforceps delivery. The duration of the developing metabolic ... | Intrapartum fetal asphyxia: clinical characteristics, diagnosis, and significance in relation to pattern of development. The clinical and fetal heart rates and acid-base characteristics and their sequelae have been reviewed in 587 patients. The relevant clinical factors in the asphyxia group were the preterm fetus, the... | [
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PMID:22252 | The rodent as an experimental tool in gerontological research. | Advances in basic gerontology has has brought along numerous methodological questions among which the growth-persistency as a function of ageing of the rodents, particularly the rat, plays an intriguing role. The fact that, the rat's growth may proceed for more than half of the lifetime was confirmed by many authors. W... | The rodent as an experimental tool in gerontological research. Advances in basic gerontology has has brought along numerous methodological questions among which the growth-persistency as a function of ageing of the rodents, particularly the rat, plays an intriguing role. The fact that, the rat's growth may proceed for ... | [
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PMID:22253 | [Polyploidisation - a phenomenon of aging? (author's transl)]. | By means of cytophotometric determination of DNA in different cellular systems an increase in polyploidisation correlated to age could be demonstrated. The latter is well demonstrable if compensatory hyperplasia or hypertrophy occurs. It is discussed that cellular systems of older individuals can increase their DNA - c... | [Polyploidisation - a phenomenon of aging? (author's transl)]. By means of cytophotometric determination of DNA in different cellular systems an increase in polyploidisation correlated to age could be demonstrated. The latter is well demonstrable if compensatory hyperplasia or hypertrophy occurs. It is discussed that c... | [
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PMID:22254 | [Tensibility measurements on the rats aorta (author's transl)]. | II. Elasticity Parameters in Various Ages Power-extension diagrams of longitudinal and transversal stripes of the Aorta thoracica were recorded by means of an elctro-mechanical measuring instrument. The samples were taken from 108 male Sprague-Dawley rats aged 9, 15 and 24 months. The following parameters describing ag... | [Tensibility measurements on the rats aorta (author's transl)]. II. Elasticity Parameters in Various Ages Power-extension diagrams of longitudinal and transversal stripes of the Aorta thoracica were recorded by means of an elctro-mechanical measuring instrument. The samples were taken from 108 male Sprague-Dawley rats ... | [
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PMID:22255 | Long-term tryptophan restriction and aging in the rat. | Growth-retarded rats fed a tryptophan deficient diet at 21 days for periods of 6-22 months were shown to reach normal body weight when subsequently fed Purina Rat Chow. They demonstrated an increased ability over similar aged controls to recover from hypothermia induced by 3-minute whole-body ice water immersion, were ... | Long-term tryptophan restriction and aging in the rat. Growth-retarded rats fed a tryptophan deficient diet at 21 days for periods of 6-22 months were shown to reach normal body weight when subsequently fed Purina Rat Chow. They demonstrated an increased ability over similar aged controls to recover from hypothermia in... | [
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PMID:22256 | The age dependence of bile acid metabolism in rats. | The age dependence of bile acid metabolism in rats was investigated and the following results were obtained. 1) Synthesis rate, pool size and total secretion decreased in old rats (24 month) significantly compared to young rats (6 weeks). 2) The quotient of taurine to glycine conjugates is is significant lower in old r... | The age dependence of bile acid metabolism in rats. The age dependence of bile acid metabolism in rats was investigated and the following results were obtained. 1) Synthesis rate, pool size and total secretion decreased in old rats (24 month) significantly compared to young rats (6 weeks). 2) The quotient of taurine to... | [
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PMID:22257 | Age-dependent changes of the protein synthetic machinery of liver cell cytoplasm as revealed by electron microscopic morphometry. | Complete electron microscopic morphometric explorations of the liver were carry out in groups of 5 each young, adult and old female Wistar rats. In addition, livers were studied 1, 5, 10, 20 days after 2/3 hepatectomy in old rats. Characteristic age-dependent change: Decrease of the surface density of total endoplasmic... | Age-dependent changes of the protein synthetic machinery of liver cell cytoplasm as revealed by electron microscopic morphometry. Complete electron microscopic morphometric explorations of the liver were carry out in groups of 5 each young, adult and old female Wistar rats. In addition, livers were studied 1, 5, 10, 20... | [
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PMID:22258 | [Age-dependent metabolism and polymerisation of collagen (author's transl)]. | Investigations of collagen metabolism on the one side and of crosslinking of fibres on the other side speak for the assumption that the decrease of synthesis of collagen correlates with an increase of its crosslinking. This process can be seen in the skin of aging rats. The increase of steady crosslinks bonds represent... | [Age-dependent metabolism and polymerisation of collagen (author's transl)]. Investigations of collagen metabolism on the one side and of crosslinking of fibres on the other side speak for the assumption that the decrease of synthesis of collagen correlates with an increase of its crosslinking. This process can be seen... | [
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PMID:22259 | [Degenerative changes in the central region of aging human rib cartilage, as influenced by growing cross section diameter (author's transl)]. | In the centre of aged human rib cartilage, a yellowing degenerative zone is seen, while in a circular peripheral region the tissue remains unchanged. The cartilage of the 12th rib shows decrease in diameter towards its free end. It therefore was used as a model to find out wether there is a critical diameter of the dif... | [Degenerative changes in the central region of aging human rib cartilage, as influenced by growing cross section diameter (author's transl)]. In the centre of aged human rib cartilage, a yellowing degenerative zone is seen, while in a circular peripheral region the tissue remains unchanged. The cartilage of the 12th ri... | [
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PMID:22272 | Acute hypocapneic hypokalemia: an latrogenic anesthetic complication. | Hyperventilation of patients during surgical anesthesia is a common practice in the United States. The results obtained in the present study re-emphasize serum potassium concentration is directly proportional to arterial carbon dioxide tension, and that for every 10 torr decrease in PaCO2 there is a concomitant 0.5 mEq... | Acute hypocapneic hypokalemia: an latrogenic anesthetic complication. Hyperventilation of patients during surgical anesthesia is a common practice in the United States. The results obtained in the present study re-emphasize serum potassium concentration is directly proportional to arterial carbon dioxide tension, and t... | [
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PMID:22276 | [Early mortality after ingestion of caustic substances]. | The authors define the management of a patient following emergency admission for the ingestion of a caustic liquid: immediate assessment by fibroscope oesophagoscopy; avoidance of all corticosteroid therapy and of the insertion of a gastric tube; parenteral alimentation. The frequency of early deaths has considerably d... | [Early mortality after ingestion of caustic substances]. The authors define the management of a patient following emergency admission for the ingestion of a caustic liquid: immediate assessment by fibroscope oesophagoscopy; avoidance of all corticosteroid therapy and of the insertion of a gastric tube; parenteral alime... | [
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PMID:22273 | Cerebral surface pH changes during asphyxia, hypotension, and circulatory arrest in the dog. | A technic is described for the measurement of cerebral surface pH in acute experiments in anesthetized dogs. During asphyxia and circulatory arrest, cerebral surface pH fell promptly and more profoundly than arterial blood or muscle surface pH; during hypovolemic hypotension (30 to 50 torr) cerebral surface pH declined... | Cerebral surface pH changes during asphyxia, hypotension, and circulatory arrest in the dog. A technic is described for the measurement of cerebral surface pH in acute experiments in anesthetized dogs. During asphyxia and circulatory arrest, cerebral surface pH fell promptly and more profoundly than arterial blood or m... | [
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PMID:22277 | [Anesthesia for esophageal surgery]. | At the present time, it is rarely necessary to operate after a digestive perforation complicating the ingestion of a caustic fluid. By contrast, cancer surgery progresses. Anaesthesia requires protection with a high degree of analgesia and curarisation. The use of a Carlens tube during oesophagectomy via a thoracic app... | [Anesthesia for esophageal surgery]. At the present time, it is rarely necessary to operate after a digestive perforation complicating the ingestion of a caustic fluid. By contrast, cancer surgery progresses. Anaesthesia requires protection with a high degree of analgesia and curarisation. The use of a Carlens tube dur... | [
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PMID:22278 | [Surgical treatment of caustic esophagogastric stenosis in the chronic phase]. | The authors report the results of 26 oesophagoplasties carried out using the descending colon for oesophageal stenosis as a result of a caustic lesion. Superior: in 5 cases the anastomosis being made to the pharynx. Inferior: 8 associated gastric lesions being treated either by resection or by short circuit. The remain... | [Surgical treatment of caustic esophagogastric stenosis in the chronic phase]. The authors report the results of 26 oesophagoplasties carried out using the descending colon for oesophageal stenosis as a result of a caustic lesion. Superior: in 5 cases the anastomosis being made to the pharynx. Inferior: 8 associated ga... | [
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PMID:22279 | [Intensive care and diet in cases of caustic esophageal stenosis after the first eight days]. | On the basis of 12 cases of caustic burns of the oesophagus, the authors describe the technique of alimentation, once the acute phase of the first eight days has passed. From the 8th to the 15th days, calories and provided parenterally. An upper GI series is carried out on the 15th day: if the stomach is healthy, the a... | [Intensive care and diet in cases of caustic esophageal stenosis after the first eight days]. On the basis of 12 cases of caustic burns of the oesophagus, the authors describe the technique of alimentation, once the acute phase of the first eight days has passed. From the 8th to the 15th days, calories and provided par... | [
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PMID:22280 | [Caustic lesions of the esophagus in the child]. | On the basis of a study involving 21 children treated over a 10 year period, the authors describe a method for the management of a child following the ingestion of a caustic fluid: emergency oesophagoscopy to determine the extent and nature on the lesions, in severe forms, alimentation gastrostomy, which would seem to ... | [Caustic lesions of the esophagus in the child]. On the basis of a study involving 21 children treated over a 10 year period, the authors describe a method for the management of a child following the ingestion of a caustic fluid: emergency oesophagoscopy to determine the extent and nature on the lesions, in severe form... | [
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PMID:22281 | [Perforations of the cervical esophagus in attempted tracheal intubation. A report of 12 cases]. | The authors underline the factors favouring perforation of the oesophagus during intubation in the light of 12 personal cases: difficulty in intubation, use of an introducer, inexperienced operator. Such a perforation may result in mediastinitis and should be treated early with massive polyvalent antibiotics and a surg... | [Perforations of the cervical esophagus in attempted tracheal intubation. A report of 12 cases]. The authors underline the factors favouring perforation of the oesophagus during intubation in the light of 12 personal cases: difficulty in intubation, use of an introducer, inexperienced operator. Such a perforation may r... | [
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PMID:22282 | [Pharyngolaryngeal fistula and hypopharyngeal perforation resulting from difficult tracheal intubation]. | The authors report a case of lesions of the pharyngo-oesophagolaryngeal junction following difficult intubation. On the basis of the small number of cases published in recent years, they attempt to determine those factors which may permit early diagnosis before the development of complications in order that any medical... | [Pharyngolaryngeal fistula and hypopharyngeal perforation resulting from difficult tracheal intubation]. The authors report a case of lesions of the pharyngo-oesophagolaryngeal junction following difficult intubation. On the basis of the small number of cases published in recent years, they attempt to determine those f... | [
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PMID:22283 | [Surgery for carcinoma of the esophagus. Methods and techniques]. | Given the poor prognosis in carcinoma of the oesophagus, and with the aid of advances in anaesthesia and postoperative care, surgery has progressively evolved towards wider excision and a reduction in the number of operative stages. Partial oesophagectomy, with gastrolysis and gastro-oesophageal anastomosis, via a left... | [Surgery for carcinoma of the esophagus. Methods and techniques]. Given the poor prognosis in carcinoma of the oesophagus, and with the aid of advances in anaesthesia and postoperative care, surgery has progressively evolved towards wider excision and a reduction in the number of operative stages. Partial oesophagectom... | [
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PMID:22284 | [Postoperative complications in esophageal surgery]. | Apart from certain complications which may follow any surgical procedure, the authors sought to emphasise in particular the problems posed by fistulae occurring after oesophageal surgery. They draw a clear distinction between cervical fistulae which, draining adequately, do not affect the vital prognosis, merely prolon... | [Postoperative complications in esophageal surgery]. Apart from certain complications which may follow any surgical procedure, the authors sought to emphasise in particular the problems posed by fistulae occurring after oesophageal surgery. They draw a clear distinction between cervical fistulae which, draining adequat... | [
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PMID:22285 | [Preoperative assessment: value and limitations in the preparation for surgery of esophageal or cardia carcinoma]. | Pre-operative assessment of a patient suffering from a carcinoma of the oesophagus demonstrates numerous pathological features and marked malnutrition. The authors give details of their method of nutritional preparation: operation is scheduled only when the patients are restored to a state of anabolism, i.e. when daily... | [Preoperative assessment: value and limitations in the preparation for surgery of esophageal or cardia carcinoma]. Pre-operative assessment of a patient suffering from a carcinoma of the oesophagus demonstrates numerous pathological features and marked malnutrition. The authors give details of their method of nutrition... | [
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PMID:22286 | [Practical problems and results of parenteral alimentation in 60 patients undergoing surgery for neoplasms of the esophagus]. | Sixty patients suffering from a neoplasm of the oesophagus underwent surgery. All received parenteral alimentation in an intensive care unit and its value was studied, in particular in the immediate postoperative period. Describing the technique used, together with the qualitative and quantitative nature of the product... | [Practical problems and results of parenteral alimentation in 60 patients undergoing surgery for neoplasms of the esophagus]. Sixty patients suffering from a neoplasm of the oesophagus underwent surgery. All received parenteral alimentation in an intensive care unit and its value was studied, in particular in the immed... | [
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PMID:22287 | [Tracheo-bronchial intubation for surgery of the esophagus via a thoracic approach]. | Tracheo-bronchial intubation using a double-lumen Carlens tube provides the surgeon with a mediastinal operating field free of any obstruction by the lung and provides greater surgical ease than that of an assistant retracting a constantly invasive lung with tracheal intubation. This anaesthetic technique involving the... | [Tracheo-bronchial intubation for surgery of the esophagus via a thoracic approach]. Tracheo-bronchial intubation using a double-lumen Carlens tube provides the surgeon with a mediastinal operating field free of any obstruction by the lung and provides greater surgical ease than that of an assistant retracting a consta... | [
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PMID:22288 | [The influence of preoperative irradiation on postoperative complications in surgical treatment of carcinoma of the esophagus]. | Over a 15 year period, the authors operated upon 650 patients suffering from carcinoma of the oesophagus. Amongst them, 185 underwent pre-operative irradiation. The latter appears to increase the percentage in whom excision was possible. By contrast, the occurence rate of postoperative complications is essentially the ... | [The influence of preoperative irradiation on postoperative complications in surgical treatment of carcinoma of the esophagus]. Over a 15 year period, the authors operated upon 650 patients suffering from carcinoma of the oesophagus. Amongst them, 185 underwent pre-operative irradiation. The latter appears to increase ... | [
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PMID:22289 | [The value of early routine radiological examination following esophagectomy for carcinoma of the lower third of the esophagus]. | An early upper gastrointestinal series may be carried out on a routine basis after recovery of the postoperative ileus and makes it possible to confirm the good quality of the anastomoses or, by contrast, reveal a benign fistula. Under some circumstances, it may be carried out very early following the development of po... | [The value of early routine radiological examination following esophagectomy for carcinoma of the lower third of the esophagus]. An early upper gastrointestinal series may be carried out on a routine basis after recovery of the postoperative ileus and makes it possible to confirm the good quality of the anastomoses or,... | [
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PMID:22290 | [Postoperative pulmonary complications following surgery for carcinoma of the esophagus]. | Pulmonary complications frequently occur during the postoperative period following surgery for neoplasms of the oesophagus. The aetiology varies according to the time of their onset but the clinical signs and treatment are essentially the same. The problems encountered and related either to anaesthesia, to the surgical... | [Postoperative pulmonary complications following surgery for carcinoma of the esophagus]. Pulmonary complications frequently occur during the postoperative period following surgery for neoplasms of the oesophagus. The aetiology varies according to the time of their onset but the clinical signs and treatment are essenti... | [
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PMID:22291 | [Pulmonary complications of esophagectomy for carcinoma of the middle third of the esophagus]. | The authors studied 20 patients undergoing operation for a carcinoma of the middle third of the oesophagus during the period January 1972 to April 1975. Postoperative pulmonary complications are extremely common in such patients. All the patients had pulmonary function study results which were compatible with this type... | [Pulmonary complications of esophagectomy for carcinoma of the middle third of the esophagus]. The authors studied 20 patients undergoing operation for a carcinoma of the middle third of the oesophagus during the period January 1972 to April 1975. Postoperative pulmonary complications are extremely common in such patie... | [
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PMID:22294 | [Peroperative sinus arrest in a patient with sick sinus syndrome (apropos of a case)]. | A sinus arrest occured during a surgical intervention in a patient suffering from a sinus nodal dysfunction. The Fentanyl acetate used as an analgésic, seems to have played an important role in the genesis of the accident, depressing sinusal and junctional automatisms. Though unusual, this complication leads to a furth... | [Peroperative sinus arrest in a patient with sick sinus syndrome (apropos of a case)]. A sinus arrest occured during a surgical intervention in a patient suffering from a sinus nodal dysfunction. The Fentanyl acetate used as an analgésic, seems to have played an important role in the genesis of the accident, depressing... | [
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PMID:22295 | [Trial droperidol premedication in infants and children]. | Droperidol premedication for children (0.3 to 0.5 mg/kg) was compared with pentobarbital and Dolosal--promethazine). Results are analyzed using criteria proposed by Burken and Nisbet. Droperidol compared very favourably with the order drugs. However a decrease in efficacy was noted with infants and neuw-born children, ... | [Trial droperidol premedication in infants and children]. Droperidol premedication for children (0.3 to 0.5 mg/kg) was compared with pentobarbital and Dolosal--promethazine). Results are analyzed using criteria proposed by Burken and Nisbet. Droperidol compared very favourably with the order drugs. However a decrease i... | [
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PMID:22297 | [Prevention by pindolol of electrocardiographic changes during bronchoscopy performed under local and general anesthesia]. | Sixty patients were studied with respect to ECG modifications during bronchoscopy under local or general anesthesia, using dynamic electrocardiography. The increase in heart rate and incidence of extra-systoles were greater under local than general anesthesia. When pindolol, a beta-blocker with practically no bronchosp... | [Prevention by pindolol of electrocardiographic changes during bronchoscopy performed under local and general anesthesia]. Sixty patients were studied with respect to ECG modifications during bronchoscopy under local or general anesthesia, using dynamic electrocardiography. The increase in heart rate and incidence of e... | [
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PMID:22298 | [Electric burns in the operating room. Apropos of 4 cases]. | Four cases of patients suffering from peroperative skin burns at electrocardioscope electrode sites are reported. They were the result of incorrect function of the cutting diathermy, (error of internal or external connection). Use of the electrocardioscope with a "floating input" protects the patient against this type ... | [Electric burns in the operating room. Apropos of 4 cases]. Four cases of patients suffering from peroperative skin burns at electrocardioscope electrode sites are reported. They were the result of incorrect function of the cutting diathermy, (error of internal or external connection). Use of the electrocardioscope wit... | [
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PMID:22300 | [A case of survival after 65 hours of immersion in the Mediterranean]. | Survical time of a man immerged in sea water at a mean temperature of 20 degrees C was 65 hours. This remarkable tolerance of a professional diver to hypothermia is attributed to his adapted clothing and safety equipment, and to favourable atmospheric conditions. On the light of this accidental immersion, one must reco... | [A case of survival after 65 hours of immersion in the Mediterranean]. Survical time of a man immerged in sea water at a mean temperature of 20 degrees C was 65 hours. This remarkable tolerance of a professional diver to hypothermia is attributed to his adapted clothing and safety equipment, and to favourable atmospher... | [
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PMID:22301 | [Comparative study of nitrogen sparing during parenteral feeding as a function of carbohydrate intake]. | The nitrogen balance of two groups of patients, A and B, was studied during the first four post-operative days. Groups A (31) received a daily intake of one liter of Totamine concentrée glucidique with glucose 10 p. 100 1,5 liter. Groups B received Totamine concentrée glucidique with glucose 30 p. 100 1,5 liter. There ... | [Comparative study of nitrogen sparing during parenteral feeding as a function of carbohydrate intake]. The nitrogen balance of two groups of patients, A and B, was studied during the first four post-operative days. Groups A (31) received a daily intake of one liter of Totamine concentrée glucidique with glucose 10 p. ... | [
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PMID:22302 | [26 cases of tracheal stenosis after prolonged intubation or tracheotomy. Personal retrospective study]. | A retrospective study over a period of 10 years, involving different hospital departments, revealed a total of 26 patients with post-intubation and/or post-prolonged tracheotomy stenosis which required surgical treatment. Predisposing factors included poor general condition, infection, iatrogenic factors related to int... | [26 cases of tracheal stenosis after prolonged intubation or tracheotomy. Personal retrospective study]. A retrospective study over a period of 10 years, involving different hospital departments, revealed a total of 26 patients with post-intubation and/or post-prolonged tracheotomy stenosis which required surgical trea... | [
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PMID:22304 | H2-Histamine receptor blocking agents in the Zollinger-Ellison syndrome. Experience in seven cases and implications for long-term therapy. | H2-Histamine receptor blocking agents metiamide and cimetidine were assessed in seven patients with Zollinger-Ellison syndrome (serum gastrin greater than 300 microgram/ml, basal acid output greater than 15 meq/h, ratio of basal acid output to maximal acid output greater than 0.5). Intravenous or oral administration of... | H2-Histamine receptor blocking agents in the Zollinger-Ellison syndrome. Experience in seven cases and implications for long-term therapy. H2-Histamine receptor blocking agents metiamide and cimetidine were assessed in seven patients with Zollinger-Ellison syndrome (serum gastrin greater than 300 microgram/ml, basal ac... | [
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PMID:22305 | Protective effect of cimetidine on aspirin-induced gastric mucosal damage. | Aspirin alters the gastric mucosal barrier as measured by ionic flux and potential difference. The effect of cimetidine on aspirin-induced alterations in gastric mucosa was studied in five normal male volunteers. Aspirin effects were studied with and without previous treatment with cimetidine. Mean (+/- SEM) basal pote... | Protective effect of cimetidine on aspirin-induced gastric mucosal damage. Aspirin alters the gastric mucosal barrier as measured by ionic flux and potential difference. The effect of cimetidine on aspirin-induced alterations in gastric mucosa was studied in five normal male volunteers. Aspirin effects were studied wit... | [
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PMID:22306 | Sjögren-type syndrome after allogeneic bone-marrow transplantation. | Four patients, treated for hematologic disorders with bone-marrow transplants from HLA-identical siblings, spontaneously complained of dry eyes 8 to 12 months after transplantation. Four allograft recipients and two recipients of autologous bone-marrow transplants were evaluated for xerophthalmia and xerostomia. Three ... | Sjögren-type syndrome after allogeneic bone-marrow transplantation. Four patients, treated for hematologic disorders with bone-marrow transplants from HLA-identical siblings, spontaneously complained of dry eyes 8 to 12 months after transplantation. Four allograft recipients and two recipients of autologous bone-marrow... | [
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PMID:22307 | Scleroderma, Sjögren-like syndrome, and chronic graft-versus-host disease. | A patient with acute myelogenous leukemia treated with an allogeneic bone marrow transplant developed acute graft-versus-host disease manifested by severe diarrhea, hepatitis, and a cutaneous eruption. As the graft-versus-host disease progressed to the chronic phase, the patient developed marked cutaneous sclerosis and... | Scleroderma, Sjögren-like syndrome, and chronic graft-versus-host disease. A patient with acute myelogenous leukemia treated with an allogeneic bone marrow transplant developed acute graft-versus-host disease manifested by severe diarrhea, hepatitis, and a cutaneous eruption. As the graft-versus-host disease progressed... | [
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PMID:22310 | Penicillic acid production in submerged culture. | Twenty known penicillic acid (PA)-producing Aspergillus and Penicillium cultures were grown under various conditions in shaken flasks to determine the highest yielding strains and their requirements for maximum toxin production. Abilities of the cultures to utilize eight different carbon sources in Raulin-Thom medium f... | Penicillic acid production in submerged culture. Twenty known penicillic acid (PA)-producing Aspergillus and Penicillium cultures were grown under various conditions in shaken flasks to determine the highest yielding strains and their requirements for maximum toxin production. Abilities of the cultures to utilize eight... | [
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PMID:22311 | Nitrogen fixation, denitrification, and pleomorphic growth in a highly pigmented Spirillum lipoferum. | A strain of Spirillum lipoferum with intense red pigmentation was isolated from the roots of Cynodon dactylon "Coastal." This isolate vigorously reduced acetylene when grown in N-free, Na-malate, semisolid agar, and it was identical to S. lipoferum strain SP7 by standard taxonomic tests. Both S. lipoferum SP7 and the C... | Nitrogen fixation, denitrification, and pleomorphic growth in a highly pigmented Spirillum lipoferum. A strain of Spirillum lipoferum with intense red pigmentation was isolated from the roots of Cynodon dactylon "Coastal." This isolate vigorously reduced acetylene when grown in N-free, Na-malate, semisolid agar, and it... | [
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PMID:22312 | The distribution of enzymes in the epidermis of the domestic cat. | With the help of enzyme histochemical methods, the distribution and activities of several oxidative and hydrolytic enzymes in the epidermis of the densely-haired domestic cat have been studied. Distinct oxidative enzyme activity could be demonstrated in all epidermal layers except the stratum corneum. Among the hydroly... | The distribution of enzymes in the epidermis of the domestic cat. With the help of enzyme histochemical methods, the distribution and activities of several oxidative and hydrolytic enzymes in the epidermis of the densely-haired domestic cat have been studied. Distinct oxidative enzyme activity could be demonstrated in ... | [
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PMID:22317 | [Acid-base balance immediately after administration of an oral contraceptive (author's transl)]. | An increase in breathing activity has often been described for the secretory phase of the menstrual cycle, for gravidity and after intramuscular application of corpus luteum and follicle hormone. The reason for this has been assumed to be a direct interaction of the hormones in the respiratory center. A shortly publish... | [Acid-base balance immediately after administration of an oral contraceptive (author's transl)]. An increase in breathing activity has often been described for the secretory phase of the menstrual cycle, for gravidity and after intramuscular application of corpus luteum and follicle hormone. The reason for this has bee... | [
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PMID:22318 | Influence of cobra venom (CoF) and pneumococcal S III capsular polysaccharide on immunologic humoral response and visceral distribution of antigens. | The immunologic response to sheep erythrocytes was compared in mice treated with Cobra venom (CoF) and with pneumococcal capsular antigen S III. Suppression of the immunologic response in both cases was attributed to the ability of both tested substances to activate the third component of complement. CoF and S III both... | Influence of cobra venom (CoF) and pneumococcal S III capsular polysaccharide on immunologic humoral response and visceral distribution of antigens. The immunologic response to sheep erythrocytes was compared in mice treated with Cobra venom (CoF) and with pneumococcal capsular antigen S III. Suppression of the immunol... | [
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PMID:22319 | Variation of human intestinal gamma-glutamyl transpeptidase in ontogenetic development. | Activity of gamma-glutamyl transpeptidase in human intestines was measured against alpha-naphthylamide and 12 gamma-glutamyl amino acids and peptides as substrate. Distinctly altered activity was found to accompany ontogenetic development. The ratio of the transpeptidase activity tested against monoglutamyl substrates ... | Variation of human intestinal gamma-glutamyl transpeptidase in ontogenetic development. Activity of gamma-glutamyl transpeptidase in human intestines was measured against alpha-naphthylamide and 12 gamma-glutamyl amino acids and peptides as substrate. Distinctly altered activity was found to accompany ontogenetic devel... | [
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PMID:22320 | Reaction of antibody with gamma-glutamyl transpeptidase. I. Isolation of the human enzyme and inhibition of its activity by antiserum. | Use of a four-step method of purification from human kidneys yielded gamma-glutamyl transpeptidase with specific activity 330 times higher than activity in the homogenate. The enzyme from human liver was also purified, and from urine two fractions of it were separated. From rabbits immunized with the enzyme from human ... | Reaction of antibody with gamma-glutamyl transpeptidase. I. Isolation of the human enzyme and inhibition of its activity by antiserum. Use of a four-step method of purification from human kidneys yielded gamma-glutamyl transpeptidase with specific activity 330 times higher than activity in the homogenate. The enzyme fr... | [
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PMID:22316 | [Heterogenity of the cryptorchid syndrome. Study of the pituitary gonadotropin reserve in 50 prepuberal bodys]. | As compared to a control group, the study of the pituitary reserve of gonadotrophins in 50, not yet puberous, cryptorchid boys, evoked that there is a heterogeneity in cryptorchism. The LH pituitary reserve may be insufficient, normal or increased; the FSH pituitary reserve may be normal or above normal. A longitudinal... | [Heterogenity of the cryptorchid syndrome. Study of the pituitary gonadotropin reserve in 50 prepuberal bodys]. As compared to a control group, the study of the pituitary reserve of gonadotrophins in 50, not yet puberous, cryptorchid boys, evoked that there is a heterogeneity in cryptorchism. The LH pituitary reserve m... | [
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PMID:22321 | Cobalt-activated acylase activity in experimental toxic liver damage. | Co++-activated acylase activity was studied in the blood serum and liver homogenates from rabbits poisoned with CCl4 in doses of 0-5 g/kg body weight intraperitoneally. Activity of this enzyme in serum increased on the first day after poisoning, but the rise was of short duration. Increased serum activity of the enzyme... | Cobalt-activated acylase activity in experimental toxic liver damage. Co++-activated acylase activity was studied in the blood serum and liver homogenates from rabbits poisoned with CCl4 in doses of 0-5 g/kg body weight intraperitoneally. Activity of this enzyme in serum increased on the first day after poisoning, but ... | [
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PMID:22322 | [Pathomorphology of the vessels of the microcirculatory bed of the serous membranes in systemic allergic vasculitis]. | The impregnation method and micropreparation were used to study the morphological changes in vessels of the microcirculatory channel of serous membranes in systemic allergic vasculites. Inflammatory and sclerotic processes in arterioles, precapillaries, capillaries, postcapillaries, and venules were found to be accompa... | [Pathomorphology of the vessels of the microcirculatory bed of the serous membranes in systemic allergic vasculitis]. The impregnation method and micropreparation were used to study the morphological changes in vessels of the microcirculatory channel of serous membranes in systemic allergic vasculites. Inflammatory and... | [
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PMID:22324 | The gold solder, gold alloy interface. | With soldering the physical properties of the basis metal must be maintained and a minimum of molten metal is used. An examination of joints in 17 gauge platinized gold wire is made with 18 k gold solder following quenching immediately after flow and cooling in air; there is a widening of grain boundaries and intergran... | The gold solder, gold alloy interface. With soldering the physical properties of the basis metal must be maintained and a minimum of molten metal is used. An examination of joints in 17 gauge platinized gold wire is made with 18 k gold solder following quenching immediately after flow and cooling in air; there is a wid... | [
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PMID:22325 | Self-association of troponin. | Ox muscle troponin was shown by equilibrium- and velocity-sedimentation studies to undergo concentration-dependent dissociation into its constituent subunits as well as self-association in imidazole buffers, pH 6.9. The extent of troponin association was found to be strongly dependent on ionic strength and also to exhi... | Self-association of troponin. Ox muscle troponin was shown by equilibrium- and velocity-sedimentation studies to undergo concentration-dependent dissociation into its constituent subunits as well as self-association in imidazole buffers, pH 6.9. The extent of troponin association was found to be strongly dependent on i... | [
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PMID:22326 | The state of aggregation of red deer (Cervus elaphus L.) beta-lactoglobulin preparations near neutral pH. | 1. The state of aggregation of four red-deer (Cervus elaphus L.) beta-lactoglobulin preparations and a control ox beta-lactoglobulin A preparation was studied by sedimentation-equilibrium experiments at pH 6.5 and 20 degrees C. 2. Three of the deer preparations and the ox control each behaved as a monomer-dimer system,... | The state of aggregation of red deer (Cervus elaphus L.) beta-lactoglobulin preparations near neutral pH. 1. The state of aggregation of four red-deer (Cervus elaphus L.) beta-lactoglobulin preparations and a control ox beta-lactoglobulin A preparation was studied by sedimentation-equilibrium experiments at pH 6.5 and ... | [
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PMID:22327 | Tritium effect in peroxidation of ehtanol by liver catalase. | 1. Simultaneous determination of the rate of appearance of 3H in water from [(1R)-1-3H1] ethanol and the rate of acetaldehyde formation in the presence of rat or ox liver catalase under conditions of steady-state generation of H2O2 allowed calculation of the 3H isotope effect. The mean value of 2.52 obtained for rat li... | Tritium effect in peroxidation of ehtanol by liver catalase. 1. Simultaneous determination of the rate of appearance of 3H in water from [(1R)-1-3H1] ethanol and the rate of acetaldehyde formation in the presence of rat or ox liver catalase under conditions of steady-state generation of H2O2 allowed calculation of the ... | [
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PMID:22328 | Affinity chromatography of the Neurospora NADP-specific glutamate dehydrogenase, its mutational variants and hybrid hexamers. | The synthesis of an affinity adsorbent, 8-(6-aminohexyl)aminoadenosine 2'-phosphate-Sepharose 4B, is described. The assembly of the 2'-AMP ligand and the hexanediamide spacer arm was synthesized in free solution before its attachment to the Sepharose matrix. This adsorbent retarded the hexameric NADP-specific glutamate... | Affinity chromatography of the Neurospora NADP-specific glutamate dehydrogenase, its mutational variants and hybrid hexamers. The synthesis of an affinity adsorbent, 8-(6-aminohexyl)aminoadenosine 2'-phosphate-Sepharose 4B, is described. The assembly of the 2'-AMP ligand and the hexanediamide spacer arm was synthesized... | [
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