id stringlengths 7 10 | title stringlengths 8 354 | content stringlengths 91 4.1k | contents stringlengths 164 4.24k | embedding listlengths 384 384 |
|---|---|---|---|---|
PMID:10587 | Unwanted effects of long-term medication in schizophrenia and depression. | Medicine is an experimental science which proceeds by trial and error, and with pharmacotherapy doctors must continually review the drugs at their disposal for both effectiveness and adverse effects. These adverse effects must be assessed not only in relation to the therapeutic effect, but also, of course, in relation ... | Unwanted effects of long-term medication in schizophrenia and depression. Medicine is an experimental science which proceeds by trial and error, and with pharmacotherapy doctors must continually review the drugs at their disposal for both effectiveness and adverse effects. These adverse effects must be assessed not onl... | [
0.026775062084197998,
0.04574698209762573,
0.056629303842782974,
0.02725609578192234,
0.0036185497883707285,
-0.017308270558714867,
0.09123881906270981,
0.03875099867582321,
-0.048484161496162415,
-0.0548449270427227,
0.022227168083190918,
-0.006366744637489319,
0.004294214304536581,
0.048... |
PMID:10589 | Malaria of the orang-utan (Pongo pygmaeus) in Borneo. | The primary objective of this project was to study the life cycle and ecology of Plasmodium pitheci, a malaria parasite of the orang-utan. The field work was based on the orang-utan rehabilitation centre in the Sepilok Forest Reserve of eastern Sabah. Two visits were made to Sepilok, the first in February and March, 19... | Malaria of the orang-utan (Pongo pygmaeus) in Borneo. The primary objective of this project was to study the life cycle and ecology of Plasmodium pitheci, a malaria parasite of the orang-utan. The field work was based on the orang-utan rehabilitation centre in the Sepilok Forest Reserve of eastern Sabah. Two visits wer... | [
0.010170984081923962,
0.02840525470674038,
0.02910356968641281,
-0.0327225960791111,
0.06653831899166107,
0.027246512472629547,
0.06909198313951492,
0.04601367190480232,
-0.059791065752506256,
0.01598494127392769,
0.09013207256793976,
-0.06888124346733093,
0.01235870085656643,
-0.033519558... |
PMID:10591 | Different susceptibilities to intracellular proteases of hemoglobin and hemoglobin-haptoglobin complex. | The susceptibilities of hemoglobin and hemoglobin-haptoglobin complex to intracellular proteases differ significantly. Hemoglobin and hemoglobin-haptoglobin complex are degested in the regions of pH 5.5-2.5 and 4.0-2.5 respectively, having pH optima at pH 4.0 and 3.0 respectively, by intracellular proteases from rat an... | Different susceptibilities to intracellular proteases of hemoglobin and hemoglobin-haptoglobin complex. The susceptibilities of hemoglobin and hemoglobin-haptoglobin complex to intracellular proteases differ significantly. Hemoglobin and hemoglobin-haptoglobin complex are degested in the regions of pH 5.5-2.5 and 4.0-2... | [
-0.07786180078983307,
-0.026153024286031723,
-0.04868430644273758,
0.0197711493819952,
0.027063559740781784,
-0.045149583369493484,
0.12492410093545914,
0.028533414006233215,
-0.04828573763370514,
0.03026520647108555,
-0.026705579832196236,
-0.0661613941192627,
-0.03213630989193916,
0.0142... |
PMID:10592 | Mechanoelectrical transduction in hyaluronic acid salt solution is an entropy-driven process. | An electrical potential develops between the ends of a column of hyaluronic salt solution displaced from a resting position by gentle pressure. A previous study demonstrated that such displacement changes the optical rotary dispersion properties of the salt, either increasing the rotation in the direction already shown... | Mechanoelectrical transduction in hyaluronic acid salt solution is an entropy-driven process. An electrical potential develops between the ends of a column of hyaluronic salt solution displaced from a resting position by gentle pressure. A previous study demonstrated that such displacement changes the optical rotary di... | [
-0.05552850663661957,
-0.017998864874243736,
0.05209476128220558,
0.003849445143714547,
-0.04531406983733177,
0.032969847321510315,
0.050726257264614105,
0.008987890556454659,
-0.03431432321667671,
0.0035302159376442432,
0.023146988824009895,
-0.05365562066435814,
0.011994007043540478,
-0.... |
PMID:10599 | Necroqizing enterocolitis with pneumatosis intestinalis in systemic lupus erythematosus and polyarteritis. | Pneumatosis intestinalis was encountered in association with fatal necrotizing enterocolitis in systemic lupus erythematosus (SLE) and polyarteritis nodosa. The radiologic identification of mottled, bubbly, and linear collections of intramural intestinal gas distinguish this ominous complication from benign pneumatosis... | Necroqizing enterocolitis with pneumatosis intestinalis in systemic lupus erythematosus and polyarteritis. Pneumatosis intestinalis was encountered in association with fatal necrotizing enterocolitis in systemic lupus erythematosus (SLE) and polyarteritis nodosa. The radiologic identification of mottled, bubbly, and li... | [
-0.02879182994365692,
-0.01958000473678112,
0.0360177606344223,
0.013447138480842113,
0.007017138414084911,
-0.07042905688285828,
0.01736912876367569,
0.05931047722697258,
-0.04035793989896774,
-0.04080519080162048,
-0.02881736494600773,
-0.0691022053360939,
0.0048429518938064575,
0.039572... |
PMID:10602 | Biochemical properties of the prostaglandin/thromboxane synthetase of human blood platelets and comparison with the synthetase of bovine seminal vesicles. | The enzyme system which synthesizes prostaglandins and thromboxanes in extracts of washed human platelets has been characterized with respect to kinetic parameters, pH and cofactor dependence, and inhibitor potencies. Arachidonate and dihomo-gamma-linolenate were shown to be mutually competitive substrates, thus provi... | Biochemical properties of the prostaglandin/thromboxane synthetase of human blood platelets and comparison with the synthetase of bovine seminal vesicles. The enzyme system which synthesizes prostaglandins and thromboxanes in extracts of washed human platelets has been characterized with respect to kinetic parameters,... | [
-0.08521005511283875,
-0.015216946601867676,
-0.05526712164282799,
0.00571866612881422,
0.004741441458463669,
0.004976095166057348,
0.05306275188922882,
0.018826913088560104,
-0.04155765473842621,
-0.031302377581596375,
0.05537889152765274,
-0.05323042720556259,
-0.0019386515486985445,
-0.... |
PMID:10603 | Tardive dyskinesia and depressive illness. | Tardive dyskinesia has been regarded as a long-term complication of neuroleptic administration to patients with the diagnosis of schizophrenia. However, nine of the first fourteen patients evaluated for an investigation of tardive dyskinesia met diagnostic criteria for depression. Neuroleptics produce blockade of post-... | Tardive dyskinesia and depressive illness. Tardive dyskinesia has been regarded as a long-term complication of neuroleptic administration to patients with the diagnosis of schizophrenia. However, nine of the first fourteen patients evaluated for an investigation of tardive dyskinesia met diagnostic criteria for depress... | [
-0.035820744931697845,
0.030867183580994606,
0.03218553587794304,
0.03831574693322182,
-0.06173966825008392,
0.015051816590130329,
0.08138342946767807,
-0.020435426384210587,
0.0019979719072580338,
-0.06049228087067604,
0.026196300983428955,
0.0026985707227140665,
0.0476967878639698,
0.059... |
PMID:10604 | Weight-bearing deficiency of the 1st metatarsal ray. | The authors have analysed a special disturbance of the statics and dynamics of the forefoot - deficient weight-bearing on the first metatarsal ray whilst walking. From the clinical point of view, the condition resulted in the development of a dorsal bunion and metatarsalgia. Forty-nine cases were treated and seven caus... | Weight-bearing deficiency of the 1st metatarsal ray. The authors have analysed a special disturbance of the statics and dynamics of the forefoot - deficient weight-bearing on the first metatarsal ray whilst walking. From the clinical point of view, the condition resulted in the development of a dorsal bunion and metata... | [
-0.030566757544875145,
-0.07047372311353683,
0.0466574989259243,
-0.00796542875468731,
-0.04062274843454361,
0.031357575207948685,
0.023906512185931206,
0.04829752445220947,
-0.048006411641836166,
-0.01962185837328434,
0.001431408105418086,
-0.06423730403184891,
-0.005022762343287468,
0.02... |
PMID:10605 | Measurement of glycolytic rates in cell suspensions using a recording pH meter. | A method for measuring continuously glycolytic rates in cell suspensions, using a recording pH meter, is described. Under the described conditions the method is very exact, sensitive and reproducible. The method can be applied to different cells and different conditions of assay calibrating in each case the pH range, c... | Measurement of glycolytic rates in cell suspensions using a recording pH meter. A method for measuring continuously glycolytic rates in cell suspensions, using a recording pH meter, is described. Under the described conditions the method is very exact, sensitive and reproducible. The method can be applied to different ... | [
-0.031350959092378616,
0.01664654351770878,
0.031531915068626404,
0.008177458308637142,
-0.002786165801808238,
-0.02357453852891922,
0.07498852908611298,
-0.006723280996084213,
-0.00647031981498003,
0.012213939800858498,
0.03496110811829567,
-0.10810893774032593,
-0.0011186759220436215,
0.... |
PMID:10606 | Characterization and induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase in rabbit bone marrow. | Benzo(a)pyrene hydroxylase activity was found in the bone marrow of control and 3MC-induced New Zealand white rabbits. This activity was localized in the microsomal fraction, was NADPH dependent and CO sensitive. The reaction was inhibited by 7,8-benzoflavone indicating that it was mediated by the 3MC-inducible form of... | Characterization and induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase in rabbit bone marrow. Benzo(a)pyrene hydroxylase activity was found in the bone marrow of control and 3MC-induced New Zealand white rabbits. This activity was localized in the microsomal fraction, was NADPH dependent and CO sensitive. The ... | [
-0.06030138209462166,
0.011511357501149178,
-0.05650195851922035,
0.0419585220515728,
0.018204620108008385,
-0.0065283747389912605,
-0.0010835898574441671,
0.04212623089551926,
-0.051128387451171875,
-0.015403405763208866,
0.03210024908185005,
-0.0748012363910675,
-0.06555573642253876,
0.0... |
PMID:10607 | NADPH dependent lipid peroxidation of calcium bound microsomes. | Rat liver microsomes prepared by a calcium aggregation method have been found capable of readily undergoing NADPH induced lipid peroxidation. Malonic dialdehyde production of calcium bound microsomes is equivalent to that attained by microsomes prepared by ultracentrifugation. In addition these calcium bound microsomes... | NADPH dependent lipid peroxidation of calcium bound microsomes. Rat liver microsomes prepared by a calcium aggregation method have been found capable of readily undergoing NADPH induced lipid peroxidation. Malonic dialdehyde production of calcium bound microsomes is equivalent to that attained by microsomes prepared by... | [
-0.03928911313414574,
0.020782683044672012,
-0.008267642930150032,
-0.009093614295125008,
-0.015215511433780193,
-0.0370199978351593,
0.009558037854731083,
0.026841148734092712,
-0.04681762680411339,
-0.016925543546676636,
-0.007927962578833103,
-0.024858472868800163,
0.010642976500093937,
... |
PMID:10608 | Molecular complexes of cocaine, its active metabolites and some other stimulants with thiamine. | Cocaine, its pharmacologically active metabolites, norcocaine benzoylnorecgonine, benzoylecgonine and other central nervous system stimulants e.g. dextrococaine, nicotine, caffeine and p-hydroxy norephedrine formed molecular complexes with thiamine. The possible implications of such an interaction are discussed. | Molecular complexes of cocaine, its active metabolites and some other stimulants with thiamine. Cocaine, its pharmacologically active metabolites, norcocaine benzoylnorecgonine, benzoylecgonine and other central nervous system stimulants e.g. dextrococaine, nicotine, caffeine and p-hydroxy norephedrine formed molecular... | [
-0.05189698934555054,
0.03159523010253906,
-0.020527038723230362,
0.0729016587138176,
0.004410141613334417,
0.018531259149312973,
0.08182687312364578,
-0.008867180906236172,
-0.038145508617162704,
-0.02138766087591648,
-0.028180336579680443,
-0.04319550469517708,
-0.012788773514330387,
0.0... |
PMID:10609 | [Immune status of indefinitely surviving rat renal allograft recipients after short course of ALS-treatment Detection of a serum blocking factor by allorosette formation inhibition test (author's transl)]. | 53 LBNF1 kidneys were grafted into L-rats. 24 untreated recipients served as control and survived 16.1 +/- 1.7 days. 14 recipients were treated with 4 ml alloantiserum (ADS) each, and the other 15 animals with 4 ml ALS each. 9 and 10 of these 14 and 15 animals survived for more than 4 months. We performed GvH-reaction ... | [Immune status of indefinitely surviving rat renal allograft recipients after short course of ALS-treatment Detection of a serum blocking factor by allorosette formation inhibition test (author's transl)]. 53 LBNF1 kidneys were grafted into L-rats. 24 untreated recipients served as control and survived 16.1 +/- 1.7 day... | [
-0.0445682629942894,
0.017092490568757057,
0.010839410126209259,
0.013935606926679611,
0.019227109849452972,
0.007569882087409496,
0.07208826392889023,
0.06690371036529541,
-0.06916376203298569,
0.0027208116371184587,
0.005617708899080753,
-0.018509410321712494,
-0.031755656003952026,
-0.0... |
PMID:10610 | [The Göttinger minipig as a laboratory animal (author's transl)]. | Blood pictures, serumelectrolytes, acid-base- and bloodgas-values of the arterial blood were determined from two juvenile and one adulte collectives of minipigs (Gottingen strain), which were kept under SPF-conditions. The results were compared with the corresponding values of human blood and should be regarded as base... | [The Göttinger minipig as a laboratory animal (author's transl)]. Blood pictures, serumelectrolytes, acid-base- and bloodgas-values of the arterial blood were determined from two juvenile and one adulte collectives of minipigs (Gottingen strain), which were kept under SPF-conditions. The results were compared with the ... | [
-0.004416984505951405,
0.0350550077855587,
0.016860829666256905,
0.00744626484811306,
0.05622632056474686,
0.014568611048161983,
0.06870901584625244,
0.07304341346025467,
-0.05524643510580063,
0.03645973652601242,
0.04388454183936119,
-0.11788500845432281,
0.016307368874549866,
0.054210685... |
PMID:10611 | [Studies on the pH-dependence, inhibition and reactivation of angiotension II-amide splitting enzymes in human erythrocytes (author's transl)]. | Aminopeptidase activity of three fractions of human erythrocytes (membranes free of hemoglobin; hemolysate free of membranes; enzyme protein fraction made free of hemoglobin by DEAE-cellulose) was measured by a NADH dependent optical test using asparaginyl1-angiotension II-amide as substrate. 1. From the enzyme protein... | [Studies on the pH-dependence, inhibition and reactivation of angiotension II-amide splitting enzymes in human erythrocytes (author's transl)]. Aminopeptidase activity of three fractions of human erythrocytes (membranes free of hemoglobin; hemolysate free of membranes; enzyme protein fraction made free of hemoglobin by... | [
-0.08821310102939606,
0.005514928605407476,
-0.04026472941040993,
0.025633295997977257,
0.010856217704713345,
-0.060261569917201996,
0.087588369846344,
0.01844593696296215,
-0.0274225901812315,
-0.01015901006758213,
-0.009702486917376518,
-0.05075283721089363,
-0.0003682852548081428,
0.053... |
PMID:10613 | Carbonic anhydrase inhibitor in trout plasma. | A manometric assay has been constructed such that carbonic anhydrase dehydration activity can be determined utilizing intact erythrocytes. It was found that unwashed whole trout blood lacks any dehydration activity quite in contrast to whole rat blood. Removal of the plasma and replacement with physiological saline res... | Carbonic anhydrase inhibitor in trout plasma. A manometric assay has been constructed such that carbonic anhydrase dehydration activity can be determined utilizing intact erythrocytes. It was found that unwashed whole trout blood lacks any dehydration activity quite in contrast to whole rat blood. Removal of the plasma... | [
-0.07886714488267899,
0.0267671849578619,
-0.007720091380178928,
0.05004914849996567,
0.0038597295060753822,
-0.07216576486825943,
0.07241018116474152,
0.047353073954582214,
-0.0736289769411087,
0.019274266436696053,
0.01568838581442833,
-0.08271005004644394,
-0.03957460820674896,
0.051143... |
PMID:10614 | Intracellular pH in cold-blooded vertebrates as a function of body temperature. | Intracellular pH (pHi) was measured in vivo in tissue of frogs (Rana catesbeiana) and turtles (Pseudemys scripta) using the DMO technique. Animals were permitted 3-8 days to come to a new steady-state body temperature (Tb) which ranged 5-32 degrees C. Least squares regression equation for pHi data are: frog blood, 8.18... | Intracellular pH in cold-blooded vertebrates as a function of body temperature. Intracellular pH (pHi) was measured in vivo in tissue of frogs (Rana catesbeiana) and turtles (Pseudemys scripta) using the DMO technique. Animals were permitted 3-8 days to come to a new steady-state body temperature (Tb) which ranged 5-32... | [
-0.0646136999130249,
-0.011035309173166752,
0.05897248536348343,
-0.003437742590904236,
0.05265047773718834,
0.014486903324723244,
0.12059538811445236,
0.027960583567619324,
-0.021797899156808853,
0.03543732315301895,
0.022729989141225815,
-0.11762401461601257,
-0.00193084217607975,
0.0597... |
PMID:10615 | Model studies of intracellular acid-base temperature responses in ectotherms. | Measurements of intracellular pH (pHi) in air-breathing ectotherms have only been made in the steady state; these pHi indicate that protein charge state, measured as alpha imidazole (alphaIM), the fractional dissociation of protein histidine imidazole groups, is preserved when ectotherm tissues change temperature in vi... | Model studies of intracellular acid-base temperature responses in ectotherms. Measurements of intracellular pH (pHi) in air-breathing ectotherms have only been made in the steady state; these pHi indicate that protein charge state, measured as alpha imidazole (alphaIM), the fractional dissociation of protein histidine ... | [
-0.0870787501335144,
-0.008835045620799065,
0.05482479929924011,
0.025708485394716263,
0.03334799036383629,
-0.0038112180773168802,
0.080389104783535,
0.033303920179605484,
0.003353507723659277,
0.02538486197590828,
0.012725620530545712,
-0.09524284303188324,
0.006534795742481947,
0.071885... |
PMID:10616 | Intracellular buffering of heart and skeletal muscles during the onset of hypercapnia. | Changes in the total CO2 content of tissues were determined in order to characterize variations in intracellular acid-base parameters during the onset of hypercapnia. Within two minutes after an increasement in the CO2 tension of the inspired air of rats, there were large increases in the intracellular bicarbonate conc... | Intracellular buffering of heart and skeletal muscles during the onset of hypercapnia. Changes in the total CO2 content of tissues were determined in order to characterize variations in intracellular acid-base parameters during the onset of hypercapnia. Within two minutes after an increasement in the CO2 tension of the... | [
-0.026135766878724098,
-0.034921422600746155,
0.036385003477334976,
0.021575376391410828,
-0.014556421898305416,
-0.019885005429387093,
0.06891749799251556,
-0.007607981562614441,
0.01528098899871111,
-0.022764449939131737,
0.009159722365438938,
-0.11366923153400421,
-0.04440061375498772,
... |
PMID:10618 | The effect of hepatectomy on the energy state and on acid-base variables of the rat brain. | The influence of hepatectomy on cerebral energy metabolism was studied in rats in which an end-to-side portacaval anastomosis had been performed one week earlier. The hepatectomy gave rise to an exaggeration of the increase in tissue ammonia content resulting from the shunt. Three hours after the hepatectomy there was ... | The effect of hepatectomy on the energy state and on acid-base variables of the rat brain. The influence of hepatectomy on cerebral energy metabolism was studied in rats in which an end-to-side portacaval anastomosis had been performed one week earlier. The hepatectomy gave rise to an exaggeration of the increase in ti... | [
0.006319120991975069,
-0.01421874389052391,
0.06579016894102097,
0.023640556260943413,
0.026641463860869408,
0.03404161334037781,
0.06912964582443237,
0.03812399134039879,
-0.06044619157910347,
-0.005735209211707115,
0.05293426662683487,
-0.03371889516711235,
-0.005351743195205927,
0.05350... |
PMID:10619 | Microcalorimetric measurements of heat production in human erythrocytes. Heat effect during methylene blue stimulation. | The metabolic activity in human erythrocytes during stimulation with 10(-4) mol/l methylene blue has been studied by a microcalorimetric method. Simultaneous measurements were performed on cells from the same preparation suspended in different media. Mean values for the ratios between heat effect values were 7.1 +/- 1.... | Microcalorimetric measurements of heat production in human erythrocytes. Heat effect during methylene blue stimulation. The metabolic activity in human erythrocytes during stimulation with 10(-4) mol/l methylene blue has been studied by a microcalorimetric method. Simultaneous measurements were performed on cells from ... | [
-0.02365044318139553,
0.015086116269230843,
0.01983659528195858,
-0.016504153609275818,
0.03098219633102417,
0.00326926214620471,
0.030630216002464294,
0.02415718138217926,
-0.012311946600675583,
-0.015557483769953251,
-0.010588271543383598,
-0.08500567078590393,
-0.014687562361359596,
0.0... |
PMID:10620 | Effect of the histamine H2-receptor antagonist, cimetidine, on gastric secretion and serum gastrin during insulin infusion in Man. | Cimetidine infusion (100 mg h-1) reduced the acid secretory response to insulin infusion (0.03 units Kg-1h-1) when compared to paired control tests in 6 healthy volunteers. There was no significant difference between cimetidine and control tests in terms of pepsin output or serum gastrin concentrations. Cimetidine also... | Effect of the histamine H2-receptor antagonist, cimetidine, on gastric secretion and serum gastrin during insulin infusion in Man. Cimetidine infusion (100 mg h-1) reduced the acid secretory response to insulin infusion (0.03 units Kg-1h-1) when compared to paired control tests in 6 healthy volunteers. There was no sig... | [
0.01970069669187069,
0.00014143412408884615,
-0.0059507801197469234,
0.07333162426948547,
-0.0002802037924993783,
0.0022570781875401735,
0.02989993989467621,
0.04770028591156006,
-0.0371863879263401,
-0.05821210891008377,
-0.003236915683373809,
-0.024969762191176414,
-0.00005333238368621096,... |
PMID:10621 | Effect of gastric hypersecretion on the canine duodenum. | The neutralization of acid introduced into the duodenum has been found to be less intensive in patients with duodenal ulcer than in controls. The present work studied the possibility that chronic gastric hypersecretion injures the duodenal mucosa and thereby influences the neutralization system. Gastric hypersecretion ... | Effect of gastric hypersecretion on the canine duodenum. The neutralization of acid introduced into the duodenum has been found to be less intensive in patients with duodenal ulcer than in controls. The present work studied the possibility that chronic gastric hypersecretion injures the duodenal mucosa and thereby infl... | [
-0.02156052179634571,
-0.003770079929381609,
-0.0005526682361960411,
0.06707415729761124,
0.011150054633617401,
-0.04346057400107384,
0.027198031544685364,
0.043257925659418106,
-0.02548806555569172,
-0.04059871286153793,
-0.017749739810824394,
-0.1227276548743248,
0.023532649502158165,
0.... |
PMID:10625 | Enkephalin-induced depression of single neurons in brain areas with opiate receptors--antagonism by naloxone. | Enkephalin, applied microiontophoretically, depressed spontaneous and glutamate-induced firing of single neurons in frontal cortex, caudate nucleus, and periaqueductal gray matter, where enkephalin and high concentrations of opiate receptors are found. Many of the depressions were blocked by the specific narcotic antag... | Enkephalin-induced depression of single neurons in brain areas with opiate receptors--antagonism by naloxone. Enkephalin, applied microiontophoretically, depressed spontaneous and glutamate-induced firing of single neurons in frontal cortex, caudate nucleus, and periaqueductal gray matter, where enkephalin and high con... | [
0.004950982518494129,
0.0015591845149174333,
-0.02715633623301983,
-0.040112003684043884,
-0.008256745524704456,
0.050435878336429596,
0.06312712281942368,
-0.0013109812280163169,
0.015474826097488403,
-0.04271252453327179,
-0.010591553524136543,
-0.023879026994109154,
0.05066927894949913,
... |
PMID:10622 | Structural studies on des-pentapeptide (B26-30)-insulin. III. State of aggregation, tyrosyl environment, and peptide backbone conformation in solution. | The three-dimensional structure of des-pentapeptide (B26--30)-insulin (DPI) in solution has been studied by several methods in view of the obvious fact that such knowledge would have much to bear on an understanding of the structure of the receptor-binding site of insulin. (1) The molecular weight of DPI has been studi... | Structural studies on des-pentapeptide (B26-30)-insulin. III. State of aggregation, tyrosyl environment, and peptide backbone conformation in solution. The three-dimensional structure of des-pentapeptide (B26--30)-insulin (DPI) in solution has been studied by several methods in view of the obvious fact that such knowle... | [
-0.1051066443324089,
-0.05373961105942726,
-0.022078733891248703,
-0.012494883500039577,
0.010451973415911198,
0.011042504571378231,
0.07417598366737366,
0.044128358364105225,
-0.03271960839629173,
-0.048296455293893814,
0.05161665007472038,
-0.07739968597888947,
0.011881578713655472,
0.04... |
PMID:10626 | beta-Adrenergic receptor involvement in 6-hydroxydopamine-induced supersensitivity in rat cerebral cortex. | The intraventricular administration of 6-hydroxydopamine, a procedure which destroys noradrenergic nerve terminals in the central nervous system, caused an increase in the density of beta-adrenergic receptors in rat cerebral cortex, without affecting their affinity for isoproterenol. The results suggest that changes in... | beta-Adrenergic receptor involvement in 6-hydroxydopamine-induced supersensitivity in rat cerebral cortex. The intraventricular administration of 6-hydroxydopamine, a procedure which destroys noradrenergic nerve terminals in the central nervous system, caused an increase in the density of beta-adrenergic receptors in r... | [
0.013590252958238125,
-0.014792204834520817,
-0.03080638498067856,
-0.0012904003961011767,
-0.029263770207762718,
0.03480858355760574,
0.08835241943597794,
0.007397624664008617,
-0.044506266713142395,
-0.05361298844218254,
0.04078545421361923,
0.015603592619299889,
-0.023708267137408257,
0... |
PMID:10623 | Structural studies on des-pentapeptide (B26-30)-insulin. IV. A preliminary investigation on the hydrophobic region by employing a fluorescence probe, 1-p-toluidinylnaphthalene-8-sulphonate. | The fluorescnece porperties of 1,8-TNS in relation to the polarity and viscosity of the solvents have been studied and found to be just as useful as those of its positional isomer 2,6-TNS in the capacity of being a fluorescent probe. The properties of the hydrophobic region of insulin, des-pentapeptide (B26-30)- insuli... | Structural studies on des-pentapeptide (B26-30)-insulin. IV. A preliminary investigation on the hydrophobic region by employing a fluorescence probe, 1-p-toluidinylnaphthalene-8-sulphonate. The fluorescnece porperties of 1,8-TNS in relation to the polarity and viscosity of the solvents have been studied and found to be... | [
-0.05296482890844345,
-0.06708376109600067,
-0.024967050179839134,
0.006024399772286415,
0.01238621212542057,
-0.015320859849452972,
0.08578423410654068,
0.045160356909036636,
-0.026208575814962387,
-0.03309430554509163,
0.016149282455444336,
-0.05942152813076973,
-0.021320698782801628,
0.... |
PMID:10624 | Structural studies on des-pentapeptide (B26-30)-insulin. V. High resolution NMR studies. | Preliminary studies have been made of the 250 MHz nuclear magnetic resonance spectra of both insulin and DPI. Differences have been found between DPI and insulin spectra, which indicate that the splitting off of the B-chain C-terminal pentapeptide from insulin has brought about local changes in the conformation of the ... | Structural studies on des-pentapeptide (B26-30)-insulin. V. High resolution NMR studies. Preliminary studies have been made of the 250 MHz nuclear magnetic resonance spectra of both insulin and DPI. Differences have been found between DPI and insulin spectra, which indicate that the splitting off of the B-chain C-termi... | [
-0.07930192351341248,
-0.025892097502946854,
-0.018049180507659912,
-0.02011019177734852,
-0.0029186655301600695,
-0.013199717737734318,
0.05409523472189903,
0.03278229013085365,
-0.02388898655772209,
-0.052687954157590866,
0.021400082856416702,
-0.06342650204896927,
0.009454197250306606,
... |
PMID:10628 | Ovum aging and pH imbalance as a cause of chromosomal anomalies in the hamster. | Using female hamsters mated in estrus, we have produced triploid embryos as manifestations of pregnancy wastage by combining delays of 3 to 4 hours in ferilization with exposure of the animals to hypoxia. Among the triploid embryos only XXX and XXY karotypes occurred, indicating derivation from XX-containing ova. These... | Ovum aging and pH imbalance as a cause of chromosomal anomalies in the hamster. Using female hamsters mated in estrus, we have produced triploid embryos as manifestations of pregnancy wastage by combining delays of 3 to 4 hours in ferilization with exposure of the animals to hypoxia. Among the triploid embryos only XXX... | [
-0.04180362820625305,
0.00007538588397437707,
-0.007054643239825964,
-0.004467491526156664,
-0.0050057885237038136,
0.04827417805790901,
0.014487074688076973,
0.030818458646535873,
-0.03818928450345993,
-0.01876135729253292,
0.020480141043663025,
-0.03735515847802162,
-0.01136006135493517,
... |
PMID:10629 | Choline administration: activation of tyrosine hydroxylase in dopaminergic neurons of rat brain. | The administration of choline in doses previously shown to elevate brain acetylcholine concentrations also increases the activity of tyrosine hydroxylase in rat caudate nuclei. This response can be blocked by atropine, a muscarinic antagonist. These findings indicate that choline-induced increases in acetylcholine conc... | Choline administration: activation of tyrosine hydroxylase in dopaminergic neurons of rat brain. The administration of choline in doses previously shown to elevate brain acetylcholine concentrations also increases the activity of tyrosine hydroxylase in rat caudate nuclei. This response can be blocked by atropine, a mu... | [
-0.02572186291217804,
0.02199011854827404,
-0.023584412410855293,
0.035866495221853256,
-0.09915601462125778,
0.01558446791023016,
0.08862128853797913,
0.022948013618588448,
-0.005286310333758593,
-0.04805920645594597,
0.006768980994820595,
-0.04478025436401367,
-0.006957071367651224,
0.04... |
PMID:10630 | [Capillary sample and blood gas analysis. Technic and validity]. | The authors have developed a technique of sampling and analysis of capillary blood which they describe here. Applied to 34 patients, it gives excellent correlations, both for PO2-PCO2 and pH. The advantages of capillary methods and their disadvantages are discussed. | [Capillary sample and blood gas analysis. Technic and validity]. The authors have developed a technique of sampling and analysis of capillary blood which they describe here. Applied to 34 patients, it gives excellent correlations, both for PO2-PCO2 and pH. The advantages of capillary methods and their disadvantages are... | [
-0.01540917158126831,
0.05999426916241646,
-0.0012193643487989902,
-0.0005564906750805676,
-0.011888393200933933,
-0.007721815258264542,
0.11489962041378021,
0.03592461347579956,
-0.040136225521564484,
0.0006882391171529889,
-0.01376662589609623,
-0.07972362637519836,
-0.022723138332366943,
... |
PMID:10632 | Skin changes in graft-vs-host disease. | In this review of the clinical and histopathologic manifestations of the graft-vs-host reaction, the characteristic changes in the skin are given particular emphasis, since they are among the earliest and most obvious signs of this syndrome. The acute and chronic forms of graft-vs-host disease are distinguished, with n... | Skin changes in graft-vs-host disease. In this review of the clinical and histopathologic manifestations of the graft-vs-host reaction, the characteristic changes in the skin are given particular emphasis, since they are among the earliest and most obvious signs of this syndrome. The acute and chronic forms of graft-vs... | [
-0.03278747946023941,
0.004886180628091097,
0.06384239345788956,
0.09237085282802582,
0.03399508446455002,
0.0025636807549744844,
0.07193020731210709,
0.07089067250490189,
-0.042266421020030975,
-0.0018693070160225034,
0.011924968101084232,
-0.03201519697904587,
0.010472072288393974,
-0.01... |
PMID:10633 | The introduction of SI units and the standardisation of laboratory reports: recommendations of the South African Association of Clinical Biochemists. | The change of SI units in laboratory reporting is occurring in South Africa. To assist this process and to ensure uniformity among laboratories, the Recommendations of the South African Association of Clinical Biochemists are presented. Controversial points are discussed and subunits selected. A standardised format of ... | The introduction of SI units and the standardisation of laboratory reports: recommendations of the South African Association of Clinical Biochemists. The change of SI units in laboratory reporting is occurring in South Africa. To assist this process and to ensure uniformity among laboratories, the Recommendations of th... | [
0.00815087091177702,
0.06828922778367996,
0.04433812201023102,
0.007087121717631817,
0.03715071454644203,
-0.01277107372879982,
0.04079054296016693,
0.034862786531448364,
0.004549331031739712,
0.0407063327729702,
0.05829232931137085,
-0.048630859702825546,
-0.03884032741189003,
0.021357003... |
PMID:10634 | The effect of microaggregates in stored blood on canine pulmonary vascular resistance. | Microaggregates have been implicated as a contributory cause of respiratory distress syndrome. Blood flow and resistance changes are compared between the right and left lungs following the selective administration of stored autologous heparinized blood into the left pulmonary artery. Eight dogs were bled 1,160 +/- 47 c... | The effect of microaggregates in stored blood on canine pulmonary vascular resistance. Microaggregates have been implicated as a contributory cause of respiratory distress syndrome. Blood flow and resistance changes are compared between the right and left lungs following the selective administration of stored autologou... | [
-0.0720277652144432,
0.00107553880661726,
-0.019768601283431053,
0.04260089248418808,
0.03949623182415962,
0.034751664847135544,
0.03656656667590141,
0.02807622216641903,
-0.025902535766363144,
0.05065997317433357,
-0.04295344650745392,
-0.06615079939365387,
-0.014743261970579624,
0.033449... |
PMID:10636 | Purification and properties of human factor IXa. | Human factor IXa was purified 5,000-fold from serum by ion exchange chromatography. The preparation was free from other clotting factors. Both pH sensitivity and heat stability of purified factor IXa appeared to be different from those of factor IX in the plasma. The molecular weight of human factor IXa is 80,000 as es... | Purification and properties of human factor IXa. Human factor IXa was purified 5,000-fold from serum by ion exchange chromatography. The preparation was free from other clotting factors. Both pH sensitivity and heat stability of purified factor IXa appeared to be different from those of factor IX in the plasma. The mol... | [
-0.09204500913619995,
-0.004150068387389183,
-0.032698530703783035,
0.014046608470380306,
-0.0009289099252782762,
-0.01600988768041134,
0.0698840469121933,
0.012899122200906277,
-0.03797568753361702,
-0.006452083121985197,
-0.009741261601448059,
-0.09249049425125122,
0.0132296746596694,
0.... |
PMID:10637 | Reactivity of fibrinogen crosslinking sites in the absence of thrombin. | The reactivity of fibrinogen crosslinking sites with thrombin-free, preactivated factor XIII (F. XIIIa) was investigated under different conditions such as increased ionic strength, presence of urea, protamine sulfate (PS) or of varying concentrations of monodansylcadaverine (MDC). Crosslinking and incorporation of MDC... | Reactivity of fibrinogen crosslinking sites in the absence of thrombin. The reactivity of fibrinogen crosslinking sites with thrombin-free, preactivated factor XIII (F. XIIIa) was investigated under different conditions such as increased ionic strength, presence of urea, protamine sulfate (PS) or of varying concentrati... | [
-0.1067492812871933,
-0.02903636172413826,
-0.0206789281219244,
0.039574045687913895,
0.04321619123220444,
-0.006662181578576565,
0.0265378188341856,
0.041385915130376816,
-0.056509364396333694,
-0.01156922522932291,
0.021098263561725616,
-0.05414929613471031,
-0.00766343716531992,
0.02987... |
PMID:10638 | Aggregation of platelets and inert particles induced by thrombin. | Thrombin-induced platelet aggregation and release were investigated in washed platelet suspensions and in suspensions of inert particles in order to evaluate the role of fibrinogen-fibrin transformation in aggregometer tracings. Thrombin (0.25-2.0 U/ml) produced two waves of light transmission increase (LTI) in both pl... | Aggregation of platelets and inert particles induced by thrombin. Thrombin-induced platelet aggregation and release were investigated in washed platelet suspensions and in suspensions of inert particles in order to evaluate the role of fibrinogen-fibrin transformation in aggregometer tracings. Thrombin (0.25-2.0 U/ml) ... | [
-0.06189412251114845,
-0.0149363549426198,
-0.013834366574883461,
0.0095006562769413,
0.014904206618666649,
0.009446765296161175,
0.04412924498319626,
0.05134139955043793,
-0.015487493947148323,
0.004598482511937618,
0.026273807510733604,
-0.06642799824476242,
-0.01069112028926611,
0.04786... |
PMID:10643 | Human immunity to rat antigens. II. Immune responses in dialysis patients. | The immune status of 35 patients with renal failure was studied shortly after they had commenced treatment by chronic haemodialysis to see if a group with poor immunological responses could be identified. Of 27 patients who were unimmunised to start with, only two developed lymphocytoxic antibodies after a year of trea... | Human immunity to rat antigens. II. Immune responses in dialysis patients. The immune status of 35 patients with renal failure was studied shortly after they had commenced treatment by chronic haemodialysis to see if a group with poor immunological responses could be identified. Of 27 patients who were unimmunised to s... | [
-0.06423909962177277,
0.02325732260942459,
-0.004684654995799065,
0.0457821786403656,
-0.0673895850777626,
-0.06592778861522675,
0.12295926362276077,
0.06905528903007507,
-0.06500303745269775,
0.009536147117614746,
0.01105803158134222,
-0.056266214698553085,
-0.002657458418980241,
-0.01007... |
PMID:10644 | Studies on a systemic xenogeneic graft-versus-host reaction model in newborn mice. | A xenogeneic graft-versus-host reaction model is described, evoked in neonatal mice by injection of rat spleen cells, and registered as splenomegaly at day 7. The following arguments are given as support for the idea that the reaction is indeed a graft-versus-host reaction: only living rat cells can give the reaction; ... | Studies on a systemic xenogeneic graft-versus-host reaction model in newborn mice. A xenogeneic graft-versus-host reaction model is described, evoked in neonatal mice by injection of rat spleen cells, and registered as splenomegaly at day 7. The following arguments are given as support for the idea that the reaction is... | [
-0.051896873861551285,
0.001742505352012813,
0.0038445082027465105,
0.02495606057345867,
0.0052316500805318356,
-0.009795610792934895,
0.04138711094856262,
0.08387593179941177,
-0.07341217249631882,
0.011701456271111965,
0.023453082889318466,
-0.031617406755685806,
-0.02661762572824955,
0.... |
PMID:10648 | Correlation of graft-versus-host mortality and positive CML assay in the mouse. | GVH mortality was encountered in each of six parental-F1 hybrid combinations with antigenic disparity sufficient to cause strong positive CML. Mortality was encountered in only one of nine combinations in which CML is negative (or weak). The CML assay may thus be useful, but is not perfect, in prediction of GVH mortali... | Correlation of graft-versus-host mortality and positive CML assay in the mouse. GVH mortality was encountered in each of six parental-F1 hybrid combinations with antigenic disparity sufficient to cause strong positive CML. Mortality was encountered in only one of nine combinations in which CML is negative (or weak). Th... | [
-0.040993399918079376,
0.007555754389613867,
-0.052154283970594406,
0.020338624715805054,
-0.010755408555269241,
0.02144736610352993,
0.04235045239329338,
0.08103982359170914,
-0.027315547689795494,
-0.017236696556210518,
-0.021619148552417755,
-0.05608799681067467,
0.028399676084518433,
-... |
PMID:10655 | Properties of 3',5'-cyclic-AMP phosphodiesterase from Paragonimus africanus metacercariae. | 3',5'-Cyclic-AMP 5'-nucleotidohydrolase (cAMP phosphodiesterase, EC 3.1.4.17) was partial purified from metacercariae of Paragonimus africanus. The enzyme activity absolutely depends on Mg2 or Mn2+. The pH-optimum of the cAMP phosphidiesterase was found at pH 8.0. The Michaelis constant for cAMP was determined to be 5 ... | Properties of 3',5'-cyclic-AMP phosphodiesterase from Paragonimus africanus metacercariae. 3',5'-Cyclic-AMP 5'-nucleotidohydrolase (cAMP phosphodiesterase, EC 3.1.4.17) was partial purified from metacercariae of Paragonimus africanus. The enzyme activity absolutely depends on Mg2 or Mn2+. The pH-optimum of the cAMP pho... | [
-0.013870827853679657,
0.0014265910722315311,
-0.03068031370639801,
0.03961683064699173,
0.0205210130661726,
-0.016773641109466553,
0.033869095146656036,
0.07108083367347717,
-0.07940644770860672,
-0.010799621231853962,
0.06407163292169571,
-0.031078925356268883,
-0.01845470815896988,
-0.0... |
PMID:10657 | [Hydrogen ion activity in the cell]. | Literature data and results of our experiments evidence for a heterogenous hydrogen distribution in cells. Intracellular pH should be regarded as a mean activity of hydrogen ions which is the sum of activities in different phases of a cell. Intracellular pH value does not depend on the transmembrane action potential di... | [Hydrogen ion activity in the cell]. Literature data and results of our experiments evidence for a heterogenous hydrogen distribution in cells. Intracellular pH should be regarded as a mean activity of hydrogen ions which is the sum of activities in different phases of a cell. Intracellular pH value does not depend on ... | [
0.0013684642035514116,
-0.04568861052393913,
0.007388692814856768,
-0.001378242508508265,
0.028553856536746025,
-0.01658845692873001,
0.0719401016831398,
0.04698963835835457,
0.004930722527205944,
0.0088752256706357,
0.021368229761719704,
-0.10822272300720215,
0.025767695158720016,
0.03933... |
PMID:10664 | In situ dissolution of ureteral calculus. | An obstructing uric acid calculus was successfully managed by dissolution in situ. The methods used are described in detail. Perhaps not applicable in all cases, the ease of the procedure makes it worth considering especially in patients at high risk for open operative intervention. | In situ dissolution of ureteral calculus. An obstructing uric acid calculus was successfully managed by dissolution in situ. The methods used are described in detail. Perhaps not applicable in all cases, the ease of the procedure makes it worth considering especially in patients at high risk for open operative interven... | [
0.018623635172843933,
-0.007902954705059528,
0.043834514915943146,
0.02567296288907528,
-0.04990485683083534,
-0.017923735082149506,
0.019914519041776657,
0.07330326735973358,
-0.014223537407815456,
-0.0030231091659516096,
-0.00017342441424261779,
-0.08680301904678345,
0.034166641533374786,
... |
PMID:10665 | [Activity and variability of aminopeptidases and gamma-glutamyl transpeptidase of the cutaneous mucous membrane in the cow's rumen]. | The authors studied the activity, chromatographic and electrophoretic distribution of leucylarylamidase, cystinamino peptidase, and gamma-glutamyl transpeptidase of the cytoplasmatic fraction of cow's rumen mucous membrane homogenate. The results of comparative analysis draw attention to the existence of a certain numb... | [Activity and variability of aminopeptidases and gamma-glutamyl transpeptidase of the cutaneous mucous membrane in the cow's rumen]. The authors studied the activity, chromatographic and electrophoretic distribution of leucylarylamidase, cystinamino peptidase, and gamma-glutamyl transpeptidase of the cytoplasmatic frac... | [
-0.016442855820059776,
-0.05096656456589699,
-0.006318506319075823,
0.03521266579627991,
0.018420100212097168,
-0.08207419514656067,
0.06768929958343506,
0.030048297718167305,
-0.04561779275536537,
-0.006489950697869062,
0.007459372282028198,
-0.058826323598623276,
0.010379793122410774,
0.... |
PMID:10666 | [Effectiveness of various barbiturates in chickens of different ages]. | Phenobarbital, allobarbital, and pentobarbital in the doses of 40 and 80 mg per 1 kg body mass were applied intramuscularly to groups of the cockerels of the WL breed at the age of two days, one, two, and six weeks (each group had ten birds) and to eight-week-old WL cockerels in groups of five birds. The methods of cli... | [Effectiveness of various barbiturates in chickens of different ages]. Phenobarbital, allobarbital, and pentobarbital in the doses of 40 and 80 mg per 1 kg body mass were applied intramuscularly to groups of the cockerels of the WL breed at the age of two days, one, two, and six weeks (each group had ten birds) and to ... | [
-0.016356077045202255,
-0.0036793400067836046,
0.019508006051182747,
0.019439956173300743,
0.0007087491103447974,
0.057563282549381256,
0.03308725357055664,
0.03187457472085953,
-0.000531274126842618,
0.0020516770891845226,
-0.02643119916319847,
-0.059320881962776184,
-0.009786607697606087,
... |
PMID:10684 | Microsomal styrene mono-oxygenase and styrene epoxide hydrase activities in rats. | 1. Styrene epoxide formation and styrene epoxide hydration have been studied in liver, lung, kidney, heart, spleen and brain of female and male rats. 2. Styrene epoxide formation is NADPH-dependent although it is enhanced when NADH is added together with NADP. This enzymic activity is inhibited by metyrapone and SKF 52... | Microsomal styrene mono-oxygenase and styrene epoxide hydrase activities in rats. 1. Styrene epoxide formation and styrene epoxide hydration have been studied in liver, lung, kidney, heart, spleen and brain of female and male rats. 2. Styrene epoxide formation is NADPH-dependent although it is enhanced when NADH is add... | [
-0.019580580294132233,
0.011737302877008915,
0.027795616537332535,
0.01841036044061184,
0.026587260887026787,
0.0022826045751571655,
0.033054422587156296,
0.027347233146429062,
-0.034880734980106354,
-0.009175618179142475,
-0.005593788344413042,
-0.005076689645648003,
-0.04277956113219261,
... |
PMID:10685 | [Absorption, distribution and excretion of (quinuclidinyl-3 methyl)-10-phenothiazine (LM 209), a new antihistamine]. | 1. The absorption, distribution and elimination of 10-(3-quinuclidinylmethyl)-phenothiazine (LM 209) were studied in the rat and dog after oral or intravenous administration of the 35S-labelled molecule. 2. Determinations of radioactivity in the rat and dog confirmed absorption and showed that the blood levels increase... | [Absorption, distribution and excretion of (quinuclidinyl-3 methyl)-10-phenothiazine (LM 209), a new antihistamine]. 1. The absorption, distribution and elimination of 10-(3-quinuclidinylmethyl)-phenothiazine (LM 209) were studied in the rat and dog after oral or intravenous administration of the 35S-labelled molecule.... | [
-0.031357526779174805,
0.0053788707591593266,
-0.034626755863428116,
0.03670801967382431,
0.02973046898841858,
-0.02300901524722576,
0.08200955390930176,
0.0726848617196083,
-0.040991898626089096,
-0.01509393285959959,
0.04823485016822815,
-0.04799985885620117,
0.03290040045976639,
0.06582... |
PMID:10686 | Metronidazole (Flagyl): degradation by the intestinal flora. | 1. Metronidazole (Flagyl) is reduced exponentially by the contents of the rat caecum in the absence of oxygen. The rate of removal is highest at pH 7 and 37 degrees. 2. Reduction of the drug is inhibited by boiling of the caecal contents, CHCl3, Cu2+, Ag+, azodicarboxylic acid bis-dimethylamide, p-chloromercuric benzoa... | Metronidazole (Flagyl): degradation by the intestinal flora. 1. Metronidazole (Flagyl) is reduced exponentially by the contents of the rat caecum in the absence of oxygen. The rate of removal is highest at pH 7 and 37 degrees. 2. Reduction of the drug is inhibited by boiling of the caecal contents, CHCl3, Cu2+, Ag+, az... | [
-0.00819691363722086,
0.05641629919409752,
0.018000412732362747,
0.024791866540908813,
0.03964934125542641,
-0.016456283628940582,
0.038278136402368546,
0.07895104587078094,
-0.029879270121455193,
-0.031697552651166916,
0.013510691933333874,
-0.026708003133535385,
0.05543224886059761,
0.01... |
PMID:10687 | Mechanism of 2-naphthylamine oxidation catalysed by pig liver microsomes. | 1. In pig liver microsomes 2-naphthylamine-dependent NADPH oxidation, oxygen reduction, and hydroxylamine formation are linear with time for several minutes. A sharp increase in NADPH oxidation and oxygen uptake then coincides with an abrupt loss of hydroxylamine from the medium. 2. The initial rate of 2-naphthylamine ... | Mechanism of 2-naphthylamine oxidation catalysed by pig liver microsomes. 1. In pig liver microsomes 2-naphthylamine-dependent NADPH oxidation, oxygen reduction, and hydroxylamine formation are linear with time for several minutes. A sharp increase in NADPH oxidation and oxygen uptake then coincides with an abrupt loss... | [
-0.07525519281625748,
0.03977559506893158,
-0.09553933143615723,
0.03895527496933937,
0.012337669730186462,
0.03247617185115814,
0.024387886747717857,
0.025942621752619743,
-0.021692192181944847,
0.0054906574077904224,
0.0013582996325567365,
-0.04398590326309204,
0.019411372020840645,
0.00... |
PMID:10688 | Production physiology and properties of a novel fungal fibrinolytic enzyme. | A potent extracellular fibrinolytic enzyme was obtained from cultures of the imperfect fungus Fusarium semitectum under certain growth conditions. Nitrate addition to cultures increased enzyme production. The enzyme showed a versatile proteolytic activity against several protein substrates including casein, gelatin, ha... | Production physiology and properties of a novel fungal fibrinolytic enzyme. A potent extracellular fibrinolytic enzyme was obtained from cultures of the imperfect fungus Fusarium semitectum under certain growth conditions. Nitrate addition to cultures increased enzyme production. The enzyme showed a versatile proteolyt... | [
-0.060735318809747696,
0.00243566557765007,
0.049701400101184845,
-0.001650170423090458,
0.05348294973373413,
-0.013483870774507523,
0.0075500826351344585,
0.0858602374792099,
-0.08426865935325623,
0.004667523317039013,
-0.02167346514761448,
-0.05579853802919388,
-0.042923349887132645,
0.0... |
PMID:10689 | [Cleavage of alpha-L-arabinofuranoside, beta-D-glucopyranoside and beta-cellobioside of 4-nitrophenol by enzymes of various fungi - a contribution to increase the selectivity of tumor therapy]. | To carry out long-term experiments as part of a therapy concept of malignant tumours using inactive transport forms of cancerostatic substances and their specific cleavage in the acidic pH region of the tumours by application of extraneous enzymes, we require enzymes with similar catalytic and pharmacokinetic propertie... | [Cleavage of alpha-L-arabinofuranoside, beta-D-glucopyranoside and beta-cellobioside of 4-nitrophenol by enzymes of various fungi - a contribution to increase the selectivity of tumor therapy]. To carry out long-term experiments as part of a therapy concept of malignant tumours using inactive transport forms of cancero... | [
-0.037565167993307114,
-0.035930611193180084,
-0.008186325430870056,
-0.010506835766136646,
0.046147335320711136,
-0.024160277098417282,
0.015374856069684029,
0.026809200644493103,
-0.019020525738596916,
-0.01978515461087227,
0.07020807266235352,
-0.02729916013777256,
-0.05671250447630882,
... |
PMID:10690 | [On the age dependence of the intracellular proteolysis (author's transl)]. | We report the age dependent changes of the proteolytic capacity of the rat liver at pH 3.0 and pH 6.0. The total proteolytic activity increases during the whole cycle. During the weanling period the specific activity (mug substrate split x min-1 X mg liver protein-1) rises up to values about 30% higher than those of th... | [On the age dependence of the intracellular proteolysis (author's transl)]. We report the age dependent changes of the proteolytic capacity of the rat liver at pH 3.0 and pH 6.0. The total proteolytic activity increases during the whole cycle. During the weanling period the specific activity (mug substrate split x min-... | [
-0.022836433723568916,
-0.022327115759253502,
0.04548057168722153,
-0.029591809958219528,
0.007090831641107798,
-0.010254155844449997,
0.07896360009908676,
0.0256694033741951,
-0.06603951752185822,
-0.0004384621570352465,
0.027219103649258614,
-0.045506659895181656,
-0.04097927734255791,
0... |
PMID:10691 | [Study of resistance to physical stress in pregnant women: influence of standardized work on cardiovascular system, ventilation, gaseous interchange, carbohydrate metabolism and acid-base balance (author's transl)]. | 10 women in the 12th week of pregnancy were tested with 50 and 60 watts on the bicycle ergometer; 16, in the 38th week of pregnancy and 12 weeks after delivery. Heart rate, blood pressure, O2 intake, CO2 elimination, respiration rate, respiratory volume per minute, lactate, pyruvate, glucose, pCO2, base excess and pH w... | [Study of resistance to physical stress in pregnant women: influence of standardized work on cardiovascular system, ventilation, gaseous interchange, carbohydrate metabolism and acid-base balance (author's transl)]. 10 women in the 12th week of pregnancy were tested with 50 and 60 watts on the bicycle ergometer; 16, in... | [
-0.0014981436543166637,
0.017572375014424324,
-0.004092717543244362,
0.10945533215999603,
0.04480280727148056,
0.0468180887401104,
0.07576413452625275,
0.005298597272485495,
-0.03435477986931801,
-0.017197906970977783,
-0.03221829980611801,
-0.04503176733851433,
-0.04366152361035347,
0.044... |
PMID:10697 | [Relationship between thermal treatments of milk and molecular hysteresis of the milk protein system (author's transl)]. | The potentiometric titration curve of milk does not show an equilibrium curve but a hysteresis loop between pH 6.2 und pH 4.8. Hysteresis means thermodynamic metastability and cooperative changes within a structural domain. The structural domain involved in these changes is the casein micelle. Cooperative conformation ... | [Relationship between thermal treatments of milk and molecular hysteresis of the milk protein system (author's transl)]. The potentiometric titration curve of milk does not show an equilibrium curve but a hysteresis loop between pH 6.2 und pH 4.8. Hysteresis means thermodynamic metastability and cooperative changes wit... | [
-0.0518900603055954,
-0.014305655844509602,
0.018256956711411476,
0.03309788927435875,
0.023788947612047195,
-0.027537157759070396,
0.07459187507629395,
0.029930977150797844,
-0.012826525606215,
-0.024423275142908096,
-0.010201293043792248,
-0.08556187897920609,
0.05433301255106926,
-0.000... |
PMID:10693 | [Different deoxyribonuclease-activities in bull seminal plasma (author's transl)]. | By means of the in situ assay of deoxyribonucleases in DNA-containing polyacrylamide gels after separation by micro-disc-electrophoresis different deoxyribonucleases are detectable in bull seminal plasma. There are two groups of acid deoxyribonuclease-activities with a pH optimum at pH 5.0, one with a pH optimum at pH ... | [Different deoxyribonuclease-activities in bull seminal plasma (author's transl)]. By means of the in situ assay of deoxyribonucleases in DNA-containing polyacrylamide gels after separation by micro-disc-electrophoresis different deoxyribonucleases are detectable in bull seminal plasma. There are two groups of acid deo... | [
0.0067032454535365105,
0.011286824941635132,
-0.004118521697819233,
0.0009288863511756063,
0.045745912939310074,
-0.008794913999736309,
0.022852139547467232,
0.06097431108355522,
-0.027533354237675667,
-0.04465444013476372,
0.006909594405442476,
-0.08301036804914474,
0.01832648739218712,
0... |
PMID:10695 | [Effect of pregnancy on the functional state of the upper respiratory tracts]. | The author studied the condition of various components responsible for the protective function of the upper respiratory tract mucous membrane as well as the olfactory sensibility in 439 pregnant women. She found certain regularities in the change of the motor, absorbing and secretory activity of the mucous membrane and... | [Effect of pregnancy on the functional state of the upper respiratory tracts]. The author studied the condition of various components responsible for the protective function of the upper respiratory tract mucous membrane as well as the olfactory sensibility in 439 pregnant women. She found certain regularities in the c... | [
0.028750507161021233,
-0.03524637967348099,
0.03386561945080757,
0.03404000774025917,
0.030043676495552063,
0.003097180277109146,
0.14824679493904114,
0.006993480492383242,
-0.037710536271333694,
-0.027700554579496384,
-0.046742767095565796,
-0.03039497509598732,
0.0005310853593982756,
0.0... |
PMID:10696 | [Basic principles of physiotherapy for allergic diseases of the otorhinolaryngologic organs]. | Physiotherapy for allergic diseases of otorhinolaryngeal organs is often practiced without taking into consideration the stage of development of the pathologic process, its form and individual peculiarities of its course. This is partly connected with lack of data on the mechanism of the hyposensibilizing effect of phy... | [Basic principles of physiotherapy for allergic diseases of the otorhinolaryngologic organs]. Physiotherapy for allergic diseases of otorhinolaryngeal organs is often practiced without taking into consideration the stage of development of the pathologic process, its form and individual peculiarities of its course. This... | [
-0.013939020223915577,
0.02607613056898117,
0.008672957308590412,
0.02615094743669033,
-0.05745962634682655,
-0.004622546024620533,
0.08618590980768204,
0.013295087032020092,
-0.08068395406007767,
-0.04480026289820671,
0.006903161760419607,
-0.04378996416926384,
-0.007431745994836092,
0.01... |
PMID:10701 | [Glucose infusions in suspected chronic placental insufficiency caused by gestosis]. | In this study glucose load and its possible therapeutical efficiency in chronic nutritive insufficiency of the placenta is investigated. Following a definite regime glucose infusions were applied to the mother prepartually as well as subpartually in order to substitute the carbohydrate metabolism of hypotrophic fetuses... | [Glucose infusions in suspected chronic placental insufficiency caused by gestosis]. In this study glucose load and its possible therapeutical efficiency in chronic nutritive insufficiency of the placenta is investigated. Following a definite regime glucose infusions were applied to the mother prepartually as well as s... | [
-0.021512195467948914,
0.005145374685525894,
-0.04131422936916351,
0.043350398540496826,
-0.008567335084080696,
-0.003178493119776249,
0.04100256413221359,
0.03277125954627991,
-0.0496039018034935,
0.003909352235496044,
-0.02317659929394722,
-0.06731607764959335,
-0.042225826531648636,
0.0... |
PMID:10702 | Susceptibility of Staphylococcus aureus, Streptococcus pyogenes and Diplococcus pneumoniae to antibiotics. Comparison of patterns in Poland and Federal Republic of Germany. | One hundred and eighty five strains of Gram-positive cocci were tested for susceptibility to 16 antibiotics, including some newer drugs, by agar dilution technique. Of these, 100 strains (50 each isolated in Poland and Germany) were Staphylococcus aureus, 55 Streptococcus pyogenes, and 30 Diplococcus pneumoniae. Previo... | Susceptibility of Staphylococcus aureus, Streptococcus pyogenes and Diplococcus pneumoniae to antibiotics. Comparison of patterns in Poland and Federal Republic of Germany. One hundred and eighty five strains of Gram-positive cocci were tested for susceptibility to 16 antibiotics, including some newer drugs, by agar di... | [
-0.02991630509495735,
0.003763343673199415,
-0.03659297525882721,
0.017313197255134583,
0.05838451161980629,
-0.022091342136263847,
-0.008230430074036121,
0.04746171087026596,
-0.08099343627691269,
-0.02413306199014187,
-0.01037288736552,
-0.05871880054473877,
-0.009158164262771606,
-0.014... |
PMID:10703 | Sport training and some activities of human polymorphonuclear leukocyte lysosomes. | The acid phosphatase and protease, neutral protease, bactericidal and mitogenic activities were determined in the polymorphonuclear leukocyte (PMNL) lysosomes of 16 years old boys. The investigated group consisted of 20 intense sport training persons during the last six years, the control one of the same age boys witho... | Sport training and some activities of human polymorphonuclear leukocyte lysosomes. The acid phosphatase and protease, neutral protease, bactericidal and mitogenic activities were determined in the polymorphonuclear leukocyte (PMNL) lysosomes of 16 years old boys. The investigated group consisted of 20 intense sport tra... | [
-0.03855977952480316,
-0.009232894517481327,
-0.026100151240825653,
-0.014989410527050495,
-0.000619860424194485,
-0.03505927324295044,
0.049504511058330536,
0.06542864441871643,
0.013901074416935444,
-0.024485724046826363,
-0.002270865486934781,
-0.08746132999658585,
-0.025925882160663605,
... |
PMID:10705 | [Enzymatic conversion of tetradecanol in heterogenous phase by yeast-alcohol dehydrogenase]. | Alcohol dehydrogenase from yeast converts long-chain primary alcohols not only in the dissolved state, but also at the surface of undissolved particles. Tetradecanol beads with a defined surface can be produced and employed as model substrate. The reaction rate was determined by the proton release accomplished in the r... | [Enzymatic conversion of tetradecanol in heterogenous phase by yeast-alcohol dehydrogenase]. Alcohol dehydrogenase from yeast converts long-chain primary alcohols not only in the dissolved state, but also at the surface of undissolved particles. Tetradecanol beads with a defined surface can be produced and employed as ... | [
-0.026698511093854904,
-0.0058378735557198524,
0.00516191590577364,
0.007271323353052139,
-0.00564873032271862,
-0.04672040045261383,
-0.03617767244577408,
0.0784638300538063,
0.00043523742351680994,
0.00894530676305294,
0.028485113754868507,
-0.053408049046993256,
-0.021518461406230927,
-... |
PMID:10706 | [Structure-activity relationships of halogenated phenylethanolamine and phenoxypropanolamine]. | 12 compounds from the series of halogenated phenylethanolamines and phenoxypropanolamines were tested at the isolated rabbit jejunum, and the pD2-and pA2-values were determined. All the substances act beta-adrenolytically. Except for 3,4-dichloronoradrenaline, which stimulates the alpha-receptors, all the compounds sti... | [Structure-activity relationships of halogenated phenylethanolamine and phenoxypropanolamine]. 12 compounds from the series of halogenated phenylethanolamines and phenoxypropanolamines were tested at the isolated rabbit jejunum, and the pD2-and pA2-values were determined. All the substances act beta-adrenolytically. Ex... | [
-0.04664549231529236,
-0.0028841954190284014,
-0.025353701785206795,
0.03753851726651192,
0.036616191267967224,
-0.010213911533355713,
0.016820386052131653,
0.0356411337852478,
-0.06854046136140823,
-0.06868482381105423,
0.00454576825723052,
-0.038371335715055466,
-0.03307521715760231,
0.0... |
PMID:10707 | The binding of noradrenaline to human erythrocytes. | When human erythrocytes are incubated in a suspension medium containing noradrenaline, they take up noradrenaline in a reaction proceeding in two phases. In a rapid first reaction noradrenaline is bound by the cells by adsorption at pH-values above 6.0; this reaction follows Freundlich's isotherms. Subsequently, noradr... | The binding of noradrenaline to human erythrocytes. When human erythrocytes are incubated in a suspension medium containing noradrenaline, they take up noradrenaline in a reaction proceeding in two phases. In a rapid first reaction noradrenaline is bound by the cells by adsorption at pH-values above 6.0; this reaction ... | [
-0.05723591893911362,
0.006654229015111923,
-0.057692546397447586,
0.03311213478446007,
0.029287677258253098,
0.0064863478764891624,
0.10379230231046677,
-0.00951201282441616,
0.0012941645691171288,
-0.044578876346349716,
0.004772004205733538,
-0.014437745325267315,
-0.01850316673517227,
0... |
PMID:10708 | [Renal excretion of long term sulfonamides under fluid administration and modification of the urinary pH value]. | The renal excretion of sulfaclomide, sulfamerazine and sulfamethoxypyridazine is delayed by increased fluid application in rats. The simultaneous administration of sulfonamides and ammonium chloride or sodium hydrogen carbonate causes, respectively, retardation and acceleration of renal sulfonamide excretion which is c... | [Renal excretion of long term sulfonamides under fluid administration and modification of the urinary pH value]. The renal excretion of sulfaclomide, sulfamerazine and sulfamethoxypyridazine is delayed by increased fluid application in rats. The simultaneous administration of sulfonamides and ammonium chloride or sodiu... | [
-0.04847382754087448,
0.022686272859573364,
-0.006368651520460844,
0.03850148990750313,
-0.020525960251688957,
0.047813646495342255,
0.022755688056349754,
0.020835183560848236,
-0.06447821855545044,
-0.039925716817379,
0.0005004501435905695,
-0.051850564777851105,
0.047780584543943405,
0.0... |
PMID:10709 | On the behaviour of murine lymphocytes after in vitro treatment with acid mucoproteins from human serum. | Seromucoproteins from human serum were isolated by perchloric acid extraction followed by DEAE-Sephadex A-50 ion exchange chromatography. The in vitro pretreatment of spleen leukocytes with this fraction caused a dose-dependent inhibition of graft-versus-host reaction as well as an increase of their electrophoretic mob... | On the behaviour of murine lymphocytes after in vitro treatment with acid mucoproteins from human serum. Seromucoproteins from human serum were isolated by perchloric acid extraction followed by DEAE-Sephadex A-50 ion exchange chromatography. The in vitro pretreatment of spleen leukocytes with this fraction caused a do... | [
-0.06479483097791672,
0.015953628346323967,
-0.030938567593693733,
0.03397034853696823,
0.02344854548573494,
-0.002412653062492609,
0.10002157092094421,
0.08092464506626129,
-0.009008197113871574,
-0.025104915723204613,
0.030070191249251366,
-0.03548675775527954,
-0.011238913051784039,
0.0... |
PMID:10712 | Immunological mechanisms in aspirin hypersensitivity. Studies on the immunogenicity of free aspirin. | Anti-aspiryl antibodies were produced in rabbits and guinea pigs by inoculation of aspirin incorporated in complete or incomplete Freund's adjuvant. These antibodies were readily detected by passive haemagglutination using rabbit erythrocytes incubated with aspirin at alkaline pH. Aspiryl conjugates with ovalbumin, hum... | Immunological mechanisms in aspirin hypersensitivity. Studies on the immunogenicity of free aspirin. Anti-aspiryl antibodies were produced in rabbits and guinea pigs by inoculation of aspirin incorporated in complete or incomplete Freund's adjuvant. These antibodies were readily detected by passive haemagglutination us... | [
-0.09770342707633972,
0.006074944976717234,
-0.08123741298913956,
0.06362539529800415,
0.0317961648106575,
-0.035230133682489395,
0.08893068879842758,
0.10499125719070435,
-0.08181799948215485,
-0.03331368416547775,
0.050162382423877716,
-0.045966848731040955,
0.027159404009580612,
-0.0010... |
PMID:10714 | High uptake in the erythrocytes and the spleen of the quaternary dipyridylium salt paraquat injected intravenously in hypotonic solutions. | Intravenous injections of the quaternary dipyridlium salt paraquat (14C-labelled) dissolved in solutions of low tonicity result in a high uptake in the erythrocytes and concomitantly also in the spleen (red pulp), the latter being probably due to phagocytosis of paraquat-containing erythrocytes by the reticuloendotheli... | High uptake in the erythrocytes and the spleen of the quaternary dipyridylium salt paraquat injected intravenously in hypotonic solutions. Intravenous injections of the quaternary dipyridlium salt paraquat (14C-labelled) dissolved in solutions of low tonicity result in a high uptake in the erythrocytes and concomitantl... | [
-0.03692246973514557,
-0.03211032226681709,
-0.06791814416646957,
0.017602430656552315,
0.06543298065662384,
-0.013340242207050323,
0.09899632632732391,
0.09732596576213837,
-0.05907021462917328,
-0.0019259904511272907,
-0.008191174827516079,
-0.06102217733860016,
0.04763010889291763,
-0.0... |
PMID:10711 | Morphology and enzyme aktivity in rat small intestinal epithelium 6 and 12 hrs. after an alkylating agent (cyclophosphamide). | Six and twelve hours after a single i.p. dose of cyclophosphamide (100 mg/kg body weight) the activity of different "brush border enzymes" (maltase, sucrase lactase, alkaline phosphatase, gamma-glutamyl transferase) and of a lysosomal enzyme (acid phosphatase) did not change. In vivo absorption of galactose was not dim... | Morphology and enzyme aktivity in rat small intestinal epithelium 6 and 12 hrs. after an alkylating agent (cyclophosphamide). Six and twelve hours after a single i.p. dose of cyclophosphamide (100 mg/kg body weight) the activity of different "brush border enzymes" (maltase, sucrase lactase, alkaline phosphatase, gamma-... | [
-0.017875928431749344,
-0.04003440588712692,
0.017027372494339943,
0.03609450161457062,
-0.00411953404545784,
-0.09303108602762222,
0.0457114614546299,
0.05071297660470009,
-0.03559565544128418,
-0.05590970069169998,
0.06182095408439636,
-0.0681319609284401,
-0.023735420778393745,
0.014830... |
PMID:10715 | Hypertension in end-stage renal disease. The relationship between blood pressure, plasma renin, plasma renin substrate and exchangeable sodium in chronic hemodialysis patients. | Blood pressure (BP), plasma renin concentration (PRC), plasma renin substrate concentration (PRSC) and exchangeable sodium (ES) have been studied in 27 patients undergoing regular hemodialysis because of end-stage renal disease. PRC was significantly higher in the hypertensive than in the normotensive patients. The pat... | Hypertension in end-stage renal disease. The relationship between blood pressure, plasma renin, plasma renin substrate and exchangeable sodium in chronic hemodialysis patients. Blood pressure (BP), plasma renin concentration (PRC), plasma renin substrate concentration (PRSC) and exchangeable sodium (ES) have been studi... | [
-0.03643454611301422,
0.03078525699675083,
0.030375288799405098,
0.011062095873057842,
0.027278626337647438,
-0.05211677774786949,
0.07281384617090225,
0.0274070892482996,
-0.00772055285051465,
-0.03261040896177292,
0.004557231906801462,
-0.07048234343528748,
0.04432964697480202,
0.0363849... |
PMID:10716 | A new pattern of multiple endocrine adenomatosis: chemodectoma, bronchial carcinoid, GH-producing pituitary adenoma, and hyperplasia of the parathyroid glands, and antral and duodenal gastrin cells. | A female patient was found to have a chemodectoma, a GH-producing pituitary tumour and a bronchial carcinoid combined with hyperplasia of the parathyroids and of antral and duodenal gastrin cells. This combination of endocrine tumours and hyperplasias does not fit with the two multiple endocrine adenomatosis syndromes ... | A new pattern of multiple endocrine adenomatosis: chemodectoma, bronchial carcinoid, GH-producing pituitary adenoma, and hyperplasia of the parathyroid glands, and antral and duodenal gastrin cells. A female patient was found to have a chemodectoma, a GH-producing pituitary tumour and a bronchial carcinoid combined wit... | [
0.03154570981860161,
-0.008274611085653305,
0.028712470084428787,
0.015818659216165543,
0.02730271779000759,
0.0025416670832782984,
0.046706631779670715,
0.010284488089382648,
-0.04935837164521217,
-0.04522516950964928,
-0.006047036964446306,
-0.047447722405195236,
0.02220803312957287,
0.0... |
PMID:10717 | Multiple endocrine adenomatosis of mixed type. | A case of multiple endocrine adenomatosis (MEA) of mixed type is presented. The syndrome, observed in a 65 year-old female, consisted of multiple neurofibroadenomatosis, medullary thyroid carcinoma, multiple adenomata of the parathyroids, adrenal cortical adenoma and small cell anaplastic bronchogenic carcinoma. Thus, ... | Multiple endocrine adenomatosis of mixed type. A case of multiple endocrine adenomatosis (MEA) of mixed type is presented. The syndrome, observed in a 65 year-old female, consisted of multiple neurofibroadenomatosis, medullary thyroid carcinoma, multiple adenomata of the parathyroids, adrenal cortical adenoma and small... | [
-0.013794264756143093,
-0.014323828741908073,
0.0070953951217234135,
0.020652111619710922,
-0.043935950845479965,
0.01928871124982834,
0.07783837616443634,
-0.023201901465654373,
-0.043317995965480804,
-0.024994930252432823,
0.02310759946703911,
-0.07295449078083038,
-0.007702657487243414,
... |
PMID:10720 | Current dimensions of the endocrine system. | The basic and clinical sciences have become fused in the investigation of relatively new syndromes and their pathogenesis. The measurement of hormone content in serum and tissues and the elucidation of its biologic effect via the membrane and cytoplasmic receptors leads to diagnostic and prognostic accuracy. New breakt... | Current dimensions of the endocrine system. The basic and clinical sciences have become fused in the investigation of relatively new syndromes and their pathogenesis. The measurement of hormone content in serum and tissues and the elucidation of its biologic effect via the membrane and cytoplasmic receptors leads to di... | [
-0.007263983134180307,
-0.018578292801976204,
0.1138346865773201,
0.04089007154107094,
0.009539823979139328,
-0.012938406318426132,
0.09021753817796707,
0.022176777943968773,
0.015699753537774086,
-0.03518267720937729,
0.05068553239107132,
-0.03145870938897133,
-0.004526367411017418,
0.027... |
PMID:10722 | Present state of alpha- and beta-adrenergic drugs I. The adrenergic receptor. | The cardiovascular alpha adrenergic receptors evoke vasoconstriction, the cardiovascular beta receptors evoke vasodilation and cardiac stimulation. All blood vessels have both alpha and beta receptors. In some areas, for example skin and kidney, the alpha receptors predominate. In some vascular beds, for example the nu... | Present state of alpha- and beta-adrenergic drugs I. The adrenergic receptor. The cardiovascular alpha adrenergic receptors evoke vasoconstriction, the cardiovascular beta receptors evoke vasodilation and cardiac stimulation. All blood vessels have both alpha and beta receptors. In some areas, for example skin and kidn... | [
-0.007959621027112007,
-0.011335344053804874,
0.006928786635398865,
0.03901151940226555,
-0.025044217705726624,
-0.031873345375061035,
0.008964084088802338,
-0.001691275741904974,
-0.022219305858016014,
-0.058795467019081116,
-0.023789752274751663,
-0.03196001052856445,
-0.0677541121840477,
... |
PMID:10724 | Juvenile Sandhoff disease: some properties of the residual hexosaminidase in cultured fibroblasts. | The residual hexosaminidase isoenzymes in juvenile Sandhoff and infantile Sandhoff disease fibroblasts, have been determined by starch gel electrophoresis and column isoelectric focusing. Hex A and hex S are the major residual isozymes in fibroblasts from the juvenile patient, while hex B is barely detectable. Only hex... | Juvenile Sandhoff disease: some properties of the residual hexosaminidase in cultured fibroblasts. The residual hexosaminidase isoenzymes in juvenile Sandhoff and infantile Sandhoff disease fibroblasts, have been determined by starch gel electrophoresis and column isoelectric focusing. Hex A and hex S are the major res... | [
0.004879866726696491,
0.022606201469898224,
0.08684971183538437,
-0.0031967659015208483,
0.01580014079809189,
0.02734277956187725,
0.005302311386913061,
0.08338941633701324,
-0.05922628194093704,
-0.029621321707963943,
0.04373424872756004,
-0.0521729476749897,
0.022473938763141632,
-0.0180... |
PMID:10725 | Effect of sodium depletion on plasma renin concentration before and during adrenergic beta-receptor blockade with propranolol in normotensive man. | Plasma renin levels have been used to discriminate between different forms of hypertension, but how to define the normal range of plasma renin levels has not been agreed upon. Sodium depletion stimulates renin release. Evaluation of plasma renin would, therefore seem possible only in relation to sodium balance. Plasma ... | Effect of sodium depletion on plasma renin concentration before and during adrenergic beta-receptor blockade with propranolol in normotensive man. Plasma renin levels have been used to discriminate between different forms of hypertension, but how to define the normal range of plasma renin levels has not been agreed upo... | [
-0.048520635813474655,
0.03698302060365677,
0.012869962491095066,
0.02180488035082817,
-0.0020389840938150883,
-0.03998953104019165,
0.016831306740641594,
0.015009544789791107,
-0.0066299778409302235,
-0.09002592414617538,
-0.016332579776644707,
-0.04726981371641159,
0.025361603125929832,
... |
PMID:10721 | [Etiopathogenesis of necrotizing arteritis (leukocytoclastic vasculitis)]. | The small vessel's necrotizing angiitis (necrotizing microangiitis (NMA), leucocytoclastic angiitis) form a continuous spectrum from the exclusively cutaneous forms of Gougreot, to those which seriously affect the viscera, as the very acute and fatal cases of Zeek, passing through a series of intermediate phases, in wh... | [Etiopathogenesis of necrotizing arteritis (leukocytoclastic vasculitis)]. The small vessel's necrotizing angiitis (necrotizing microangiitis (NMA), leucocytoclastic angiitis) form a continuous spectrum from the exclusively cutaneous forms of Gougreot, to those which seriously affect the viscera, as the very acute and ... | [
-0.05085263028740883,
-0.0208989679813385,
-0.03754193335771561,
0.00469568744301796,
0.007333701476454735,
-0.009245606139302254,
0.08244847506284714,
0.04921935126185417,
-0.06598624587059021,
-0.049660712480545044,
-0.009783875197172165,
-0.05108402296900749,
-0.0017531861085444689,
0.0... |
PMID:10727 | Methodologic problems in plasma renin activity measurements. | The influence of pH and angiotensinase inhibitors on the in vitro generation of angiotensin I during PRA measurements has been investigated. PRA values obtained at pH 5.7 are higher than those obtained at pH 7.4. At pH 5.7, values obtained using diisopropylfluorophosphate (DRP 9 mM) as an angiotensinase inhibitor are h... | Methodologic problems in plasma renin activity measurements. The influence of pH and angiotensinase inhibitors on the in vitro generation of angiotensin I during PRA measurements has been investigated. PRA values obtained at pH 5.7 are higher than those obtained at pH 7.4. At pH 5.7, values obtained using diisopropylfl... | [
-0.07676557451486588,
0.024946710094809532,
-0.00918928999453783,
0.024418720975518227,
-0.004816260188817978,
-0.07245836406946182,
0.050910357385873795,
0.030611898750066757,
0.011935995891690254,
-0.050227899104356766,
0.027736620977520943,
-0.036048512905836105,
0.03689749538898468,
0.... |
PMID:10728 | Plasma prorenin: cryoactivation and relationship to renin substrate in normal subjects. | We previously demonstrated an inactive form of renin, termed prorenin, in the plasma of normal, hypertensive and anephric patients. Prorenin activity can be determined in plasma from the total renin activity after activation, minus the prior endogenous plasma renin activity. In the present study, conditions for cryoact... | Plasma prorenin: cryoactivation and relationship to renin substrate in normal subjects. We previously demonstrated an inactive form of renin, termed prorenin, in the plasma of normal, hypertensive and anephric patients. Prorenin activity can be determined in plasma from the total renin activity after activation, minus ... | [
-0.05393501743674278,
0.027096685022115707,
0.03737497329711914,
0.027840275317430496,
0.0034744353033602238,
-0.033857833594083786,
0.0534176267683506,
0.025265824049711227,
-0.005482067354023457,
-0.051594968885183334,
0.0008502546115778387,
-0.05273435264825821,
0.008160117082297802,
0.... |
PMID:10729 | Beta-adrenergic receptor blocking drugs in spontaneous hypertension. | Eleven beta-adrenergic receptor blocking agents and derivatives were evaluated for their ability to affect systolic arterial blood pressure and pulse rate in unanesthetized, male spontaneously hypertensive rats (SHRs) and normotensive Wistar Kyoto (WKY) controls. Animals ranged from 7 to 76 weeks of age. The subcutaneo... | Beta-adrenergic receptor blocking drugs in spontaneous hypertension. Eleven beta-adrenergic receptor blocking agents and derivatives were evaluated for their ability to affect systolic arterial blood pressure and pulse rate in unanesthetized, male spontaneously hypertensive rats (SHRs) and normotensive Wistar Kyoto (WK... | [
-0.06029766798019409,
-0.009480081498622894,
0.0014649638906121254,
-0.02207016572356224,
0.0017355935415253043,
-0.018169475719332695,
-0.0019261193228885531,
-0.01027887873351574,
-0.04210395738482475,
-0.08078405261039734,
0.016803935170173645,
0.0008071470074355602,
0.022534476593136787,... |
PMID:10730 | Modern system for treating high blood pressure based on renin profiling and vasoconstriction-volume analysis: a primary role for beta blocking drugs such as propranolol. | A new system is proposed for treating the spectrum of patients with high blood pressure. It is based on studies of the renin axis using renin profiling, pharmacologic probes and our bipolar vasoconstriction-volume hypothesis. The new system does not require renin profiling, pharmacologic testing or a vasoconstriction-v... | Modern system for treating high blood pressure based on renin profiling and vasoconstriction-volume analysis: a primary role for beta blocking drugs such as propranolol. A new system is proposed for treating the spectrum of patients with high blood pressure. It is based on studies of the renin axis using renin profilin... | [
-0.07949371635913849,
0.024379482492804527,
-0.021121852099895477,
0.004727377090603113,
0.008673137985169888,
-0.03811344876885414,
0.0197759959846735,
0.025660807266831398,
-0.005746285896748304,
-0.0831528902053833,
0.03508814051747322,
-0.013748210854828358,
0.00490349717438221,
0.0432... |
PMID:10731 | Controlled trial of fetal intensive care. | A fetal intensive care unit was formed at the Queen Victoria Memorial Hospital in 1972. Because of some doubt concerning the value of fetal intensive care, a controlled clinical trial including all high-risk patients was performed. The trial clearly showed that intensive care is associated with improved neurologic and ... | Controlled trial of fetal intensive care. A fetal intensive care unit was formed at the Queen Victoria Memorial Hospital in 1972. Because of some doubt concerning the value of fetal intensive care, a controlled clinical trial including all high-risk patients was performed. The trial clearly showed that intensive care i... | [
-0.022235257551074028,
0.05212615057826042,
0.0032574126962572336,
0.0901884064078331,
-0.004765053745359182,
0.04603329300880432,
0.018390651792287827,
0.0579431988298893,
-0.025153597816824913,
0.042999424040317535,
-0.004924474749714136,
-0.025944340974092484,
-0.05916862189769745,
0.03... |
PMID:10732 | Other hydrophilic lens environments: pH. | Although hydrophilic contact lenses are specifically designed for compatibility with the eye environment, i.e., the tears, they will, with the exception of continuous wear types, spend a significant fraction of their daily cycle in other solutions. This investigation explores the pH characteristics of certain of those ... | Other hydrophilic lens environments: pH. Although hydrophilic contact lenses are specifically designed for compatibility with the eye environment, i.e., the tears, they will, with the exception of continuous wear types, spend a significant fraction of their daily cycle in other solutions. This investigation explores th... | [
-0.05791077762842178,
0.007036617025732994,
-0.0038591332267969847,
0.07607801258563995,
-0.01752018742263317,
-0.02606119029223919,
0.07793726027011871,
0.031004302203655243,
-0.12145961821079254,
-0.015684479847550392,
-0.020990874618291855,
-0.07019011676311493,
0.015837762504816055,
0.... |
PMID:10733 | Participation of H1 and H2 histamine receptors in physiological vasodilator responses. | Histamine causes vasodilation in the dog by activation of H1 and H2 receptors blocked by mepyramine and metiamide, respectively. Experiments were conducted in anesthetized dogs to determine the participation of H1 and H2 receptors in several forms of physiological dilatation. Mepyramine attenuated both histamine-induce... | Participation of H1 and H2 histamine receptors in physiological vasodilator responses. Histamine causes vasodilation in the dog by activation of H1 and H2 receptors blocked by mepyramine and metiamide, respectively. Experiments were conducted in anesthetized dogs to determine the participation of H1 and H2 receptors in... | [
0.007253999821841717,
0.011245062574744225,
0.01251183357089758,
0.0580630749464035,
-0.05270536616444588,
-0.009756102226674557,
0.09231938421726227,
0.021273110061883926,
0.006758799310773611,
-0.022020159289240837,
0.019444618374109268,
-0.07713795453310013,
0.04491420462727547,
-0.0106... |
PMID:10734 | Maleate-induced bicarbonaturia in the dog: a carbonic anhydrase-independene effect. | Studies were performed to characterize the renal effects of maleate in anesthetized dogs. Following the intravenous administration of maleate or maleic acid (50 mg/kg), mean fractional bicarbonate excretion (CHCO3/GFR) rose to as high as 26%. Na, K, and phosphate excretion also increased markedly, whereas C1 excretion ... | Maleate-induced bicarbonaturia in the dog: a carbonic anhydrase-independene effect. Studies were performed to characterize the renal effects of maleate in anesthetized dogs. Following the intravenous administration of maleate or maleic acid (50 mg/kg), mean fractional bicarbonate excretion (CHCO3/GFR) rose to as high a... | [
-0.0397336520254612,
-0.02189198136329651,
0.011481977067887783,
0.04360656067728996,
0.014018155634403229,
-0.016389142721891403,
0.05995871499180794,
0.053626541048288345,
-0.03893277794122696,
-0.04303227737545967,
0.01816781796514988,
-0.09490932524204254,
0.0076444437727332115,
0.0820... |
PMID:10735 | Tetanic hyperpolarization of single medullated nerve fibers in sodium and lithium. | Repetitive stimulation of a single medullated nerve fiber of Xenopus yields a succession of postspike voltage-time curves which are nearly coincident until attainment of a voltage that corresponds to that of the maximum attained by the normal postspike undershoot. Initially the interspike potential returns toward a res... | Tetanic hyperpolarization of single medullated nerve fibers in sodium and lithium. Repetitive stimulation of a single medullated nerve fiber of Xenopus yields a succession of postspike voltage-time curves which are nearly coincident until attainment of a voltage that corresponds to that of the maximum attained by the n... | [
-0.013873237185180187,
0.01867622695863247,
-0.03903765231370926,
0.025900812819600105,
-0.07549340277910233,
-0.010047429241240025,
0.03352523595094681,
-0.03059786930680275,
0.01234837993979454,
0.027691541239619255,
0.01096576452255249,
-0.050445929169654846,
0.016329055652022362,
0.020... |
PMID:10736 | Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. | Glutamine synthetase (GS) is known to exist in the kidney of the rat, guinea pig, rabbit, and sheep but not in that of the dog, pig, cat, or pigeon. No data is available in man. Assay of histologically normal renal tissue obtained in human subjects during surgery for abdominal vascular disease failed to demonstrate sig... | Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. Glutamine synthetase (GS) is known to exist in the kidney of the rat, guinea pig, rabbit, and sheep but not in that of the dog, pig, cat, or pigeon. No data is available in man. Assay of histologically normal renal tissue obtained in human... | [
0.029000580310821533,
-0.055246178060770035,
0.000807333504781127,
-0.0000648799177724868,
0.024825116619467735,
-0.004119533114135265,
0.08211676776409149,
0.028337489813566208,
-0.03884125500917435,
0.024490660056471825,
-0.02721806988120079,
-0.09701676666736603,
0.040011584758758545,
0... |
PMID:10737 | Calcium uptake by subcellular fractions of human umbilical artery. | Two different mechanisms for the active accumulation of Ca2+ by subcellular fractions of human umbilical artery are described. One, located in the mitochondrial fraction, was induced by exogenous ATP or respiratory substrates (ADP and succinate) and was inhibited by azide. The other, located in the microsomal fraction,... | Calcium uptake by subcellular fractions of human umbilical artery. Two different mechanisms for the active accumulation of Ca2+ by subcellular fractions of human umbilical artery are described. One, located in the mitochondrial fraction, was induced by exogenous ATP or respiratory substrates (ADP and succinate) and was... | [
-0.06248612701892853,
-0.017828505486249924,
-0.016853269189596176,
0.015396631322801113,
-0.018245214596390724,
-0.0058426083996891975,
0.036008503288030624,
0.004180404357612133,
-0.002382562030106783,
-0.005234334152191877,
0.04729684814810753,
-0.1309954673051834,
0.009207798168063164,
... |
PMID:10738 | Intrarenal blood flow distribution in the desert quail following salt loading. | The total-kidney glomerular filtration rate (GFR) falls when birds are salt loaded. This fall in GFR is caused by glomerular intermittency. The nephrons that stop filtering are small, surface nephrons without loops of Henle. Larger nephrons with loops of Henle in the deeper regions of the kidney continue to filter duri... | Intrarenal blood flow distribution in the desert quail following salt loading. The total-kidney glomerular filtration rate (GFR) falls when birds are salt loaded. This fall in GFR is caused by glomerular intermittency. The nephrons that stop filtering are small, surface nephrons without loops of Henle. Larger nephrons ... | [
-0.0022974652238190174,
-0.017943935468792915,
-0.03222978487610817,
0.006573067978024483,
0.03875406086444855,
-0.003212164156138897,
0.03714299201965332,
0.02645142748951912,
-0.013044450432062149,
-0.007502967491745949,
-0.03259517624974251,
-0.08420120179653168,
0.04829341545701027,
0.... |
PMID:10739 | Inhibition of inotropic effect of hyperosmotic mannitol by lactate in vitro. | Isolated, isometrically contracting cat papillary muscles were used to evaluate the inotropic interactions of lactic acidosis, hypercarbic acidosis, and lactate ion with hypertonic mannitol. These studies have documented that both lactic acidosis (pH less than 7.0) and lactate ion at a normal pH inhibit the inotropic e... | Inhibition of inotropic effect of hyperosmotic mannitol by lactate in vitro. Isolated, isometrically contracting cat papillary muscles were used to evaluate the inotropic interactions of lactic acidosis, hypercarbic acidosis, and lactate ion with hypertonic mannitol. These studies have documented that both lactic acido... | [
-0.058324139565229416,
-0.03011420927941799,
0.009185399860143661,
0.0640130490064621,
-0.04307052120566368,
-0.05203606188297272,
0.06597913056612015,
0.045209553092718124,
-0.06181586533784866,
-0.054347481578588486,
0.0405530110001564,
-0.0617704838514328,
0.007926550693809986,
0.063075... |
PMID:10740 | Renal hydrogen ion secretion after release of unilateral ureteral obstruction. | The effect of 24 h of unilateral ureteral obstruction on HCO3 reabsroption and urinary acidification was studied in dogs. The postobstructed kidney (EK) had a significantly lower glomerular filtration rate and renal plasma flow than the contralateral kidney (CK). Urinary pH prior to HCO3 loading was significantly highe... | Renal hydrogen ion secretion after release of unilateral ureteral obstruction. The effect of 24 h of unilateral ureteral obstruction on HCO3 reabsroption and urinary acidification was studied in dogs. The postobstructed kidney (EK) had a significantly lower glomerular filtration rate and renal plasma flow than the cont... | [
-0.01986118033528328,
-0.018335416913032532,
0.012377710081636906,
0.08779587596654892,
-0.007450015749782324,
-0.009714427404105663,
0.05988241732120514,
0.028860101476311684,
-0.004303074907511473,
0.009610331617295742,
-0.012912911362946033,
-0.08776465058326721,
0.041374459862709045,
0... |
PMID:10741 | Effects of increased O2 and CO2 on acid secretion by dogfish gastric mucosa in vitro. | The gastric mucosa of the dogfish (Squalus acanthias), as usually prepared for in vitro chambered experiments, shows a secretory rate (JH) of about 2 mueq/cm2-h, but a potential difference (PD) of zero. Raising PCO2 from 0.05 to 0.1 atm increases JH by 40% and causes the development of a PD of about 2 mV, mucosal surfa... | Effects of increased O2 and CO2 on acid secretion by dogfish gastric mucosa in vitro. The gastric mucosa of the dogfish (Squalus acanthias), as usually prepared for in vitro chambered experiments, shows a secretory rate (JH) of about 2 mueq/cm2-h, but a potential difference (PD) of zero. Raising PCO2 from 0.05 to 0.1 a... | [
-0.04298927262425423,
-0.06875500828027725,
0.026574239134788513,
0.08476334065198898,
-0.004255254287272692,
-0.03653275594115257,
0.023151254281401634,
0.02689831517636776,
-0.045385513454675674,
-0.0035870950669050217,
0.007275241427123547,
-0.14338690042495728,
-0.04944415017962456,
0.... |
PMID:10742 | Depression and the reintegration phase of acute schizophrenia. | The authors found moderate to severe depression in 60% of a group of schizophrenic patients experiencing acute decompensations (N=30). The course of the depression was followed over an 8-week period8,during which patients were treated with depot fluphenazines. There was a statistically significant reduction in depressi... | Depression and the reintegration phase of acute schizophrenia. The authors found moderate to severe depression in 60% of a group of schizophrenic patients experiencing acute decompensations (N=30). The course of the depression was followed over an 8-week period8,during which patients were treated with depot fluphenazin... | [
-0.021541353315114975,
0.0015690301079303026,
-0.003986029420047998,
0.027554983273148537,
-0.0355541817843914,
0.06127012521028519,
0.06287050992250443,
-0.022758344188332558,
-0.020793277770280838,
-0.072441466152668,
0.04495411738753319,
-0.006549533922225237,
0.011541767977178097,
0.03... |
PMID:10743 | Self-induced depersonalization syndrome. | The author reports two cases in which depersonalization occurred during the waking consciousness of individuals who had engaged in meditative techniques designed to alter consciousness. Psychiatrists should be aware of this phenomenon, as the number organizations in the "consciousness movement" is increasing, and shoul... | Self-induced depersonalization syndrome. The author reports two cases in which depersonalization occurred during the waking consciousness of individuals who had engaged in meditative techniques designed to alter consciousness. Psychiatrists should be aware of this phenomenon, as the number organizations in the "conscio... | [
-0.03862278535962105,
0.007867418229579926,
0.017913073301315308,
-0.011834811419248581,
-0.07117735594511032,
0.06900843232870102,
0.1017833724617958,
-0.0013140770606696606,
-0.012836179696023464,
-0.024329334497451782,
0.022194400429725647,
0.02689339406788349,
0.02108321338891983,
0.03... |
PMID:10746 | Generic and trade-name antipsychotic drugs: clinical equivalence. | The clinical inequivalence of generic versus trade-name drugs has been reported for nonpsychiatric drugs but rarely for psychotropic drugs. Recent expiration of patents on some psychotropic drugs has made the evaluation of the clinical equivalence of generic versus trade-name drugs a matter of interest from methodologi... | Generic and trade-name antipsychotic drugs: clinical equivalence. The clinical inequivalence of generic versus trade-name drugs has been reported for nonpsychiatric drugs but rarely for psychotropic drugs. Recent expiration of patents on some psychotropic drugs has made the evaluation of the clinical equivalence of gen... | [
-0.05723311007022858,
-0.02206052467226982,
-0.03331568464636803,
0.017474668100476265,
-0.01385734137147665,
0.04743771627545357,
0.08915363997220993,
0.021679088473320007,
-0.0021497951820492744,
-0.03822583705186844,
0.02387775108218193,
0.03128513693809509,
0.020547736436128616,
0.0133... |
PMID:10747 | Coffee consumption among psychiatric inpatients. | Of 135 patients on an acute psychiatric ward, 34 were "high users" of coffee. The high users tended to be older, single, and have diagnoses of psychosis. They showed significantly more state anxiety than other patients, but there were no differences in trait anxiety or MMPI scores. Further research is suggested to dete... | Coffee consumption among psychiatric inpatients. Of 135 patients on an acute psychiatric ward, 34 were "high users" of coffee. The high users tended to be older, single, and have diagnoses of psychosis. They showed significantly more state anxiety than other patients, but there were no differences in trait anxiety or M... | [
0.01096409372985363,
0.01913675107061863,
-0.028490284457802773,
0.032541487365961075,
0.0032787062227725983,
0.026866532862186432,
0.09321928769350052,
0.04717591032385826,
-0.009790284559130669,
-0.028274187818169594,
0.03299052268266678,
-0.012533440254628658,
-0.03184221312403679,
-0.0... |
PMID:10748 | Catatonialike symptomatology and withdrawal dyskinesias. | The authors describes a patient who presented catatonialike symptoms and dyskinesias associated with glutethimide discontinuance and antihistamine use. He hypothesizes that altered dopamine metabolism may produce some of the unusual neuropsychiatric characteristics of glutethimide withdrawal. Drug-withdrawal catatonia ... | Catatonialike symptomatology and withdrawal dyskinesias. The authors describes a patient who presented catatonialike symptoms and dyskinesias associated with glutethimide discontinuance and antihistamine use. He hypothesizes that altered dopamine metabolism may produce some of the unusual neuropsychiatric characteristi... | [
0.019190365448594093,
0.012293525971472263,
-0.00847690925002098,
0.050985705107450485,
-0.011866546235978603,
-0.008091756142675877,
0.09508545696735382,
0.01930682733654976,
-0.0007468715193681419,
0.0009742813999764621,
-0.03334800526499748,
0.006752920337021351,
0.01388914231210947,
0.... |
PMID:10751 | Formal presentation at a scientific meeting. | The giving of a ten minute scientific communication is an art form peculiar to researchers who frequently fail to research the technology required for the performance. Careful selection of the scientific material to be included, the audio-visual aids to support it, and adequate rehearsal before presentation to a critic... | Formal presentation at a scientific meeting. The giving of a ten minute scientific communication is an art form peculiar to researchers who frequently fail to research the technology required for the performance. Careful selection of the scientific material to be included, the audio-visual aids to support it, and adequ... | [
-0.011414330452680588,
0.0524592287838459,
0.006350165698677301,
-0.015149387530982494,
0.049922194331884384,
0.03500698506832123,
0.0008321510395035148,
0.04836658015847206,
0.03398647904396057,
-0.012046764604747295,
-0.025504646822810173,
-0.0327291339635849,
0.0019102779915556312,
0.00... |
PMID:10752 | Intravenous flunitrazepam as an anesthetic induction agent. | The effects of the fluorinated benzodiazepine compound flunitrazepam were studied in eighty patients. The drug was administered intravenously in a standard dose of 2 mg, 3 mg, or 4 mg to supplement lumbar epidural analgesia. Induction was smooth and pleasant. The sleep onset time was dose related and exceeded one minut... | Intravenous flunitrazepam as an anesthetic induction agent. The effects of the fluorinated benzodiazepine compound flunitrazepam were studied in eighty patients. The drug was administered intravenously in a standard dose of 2 mg, 3 mg, or 4 mg to supplement lumbar epidural analgesia. Induction was smooth and pleasant. ... | [
-0.027447838336229324,
0.007133683189749718,
-0.00011665812780847773,
0.035014960914850235,
0.008520370349287987,
0.030276304110884666,
0.0719560831785202,
0.03777652233839035,
0.0064731622114777565,
-0.026329519227147102,
-0.021493352949619293,
-0.012725841253995895,
0.012748965062201023,
... |
PMID:10757 | In vitro effects of certain neurohumors on ultrastructural change of the chick embryonic thyroid gland. | In vitro effects of certain neurohumors, on ultrastructure of 14 days old chick embryonic thyroid gland, has been studied. When the chick embryonic thyroid gland was cultivated in vitro, in the medium containing neurohumors like acetylcholine, adrenaline and histamine for a definite period in a particular sequence and ... | In vitro effects of certain neurohumors on ultrastructural change of the chick embryonic thyroid gland. In vitro effects of certain neurohumors, on ultrastructure of 14 days old chick embryonic thyroid gland, has been studied. When the chick embryonic thyroid gland was cultivated in vitro, in the medium containing neur... | [
0.039642974734306335,
-0.02181142196059227,
0.039731211960315704,
0.022259421646595,
-0.037427354604005814,
0.0435844324529171,
0.05729588121175766,
0.01071004569530487,
-0.07352723926305771,
-0.019087133929133415,
-0.0068701282143592834,
-0.012548130936920643,
-0.00653774244710803,
0.0548... |
PMID:10758 | Histological response of various endocrine glands after administration of certain neurohumors in chicks. | Histological response of various endocrine glands like pituitary, adrenal, testes and pancreas after administration of certain neurohumors like acetylcholine, adrenaline and histamine in a particular dose and sequence, has been carried out in white leghorn chicks. Result of this study revealed that administration of th... | Histological response of various endocrine glands after administration of certain neurohumors in chicks. Histological response of various endocrine glands like pituitary, adrenal, testes and pancreas after administration of certain neurohumors like acetylcholine, adrenaline and histamine in a particular dose and sequen... | [
0.029006334021687508,
-0.024618200957775116,
0.061052680015563965,
0.04509833827614784,
-0.0172153078019619,
0.04326648637652397,
0.10707665979862213,
-0.009002959355711937,
-0.03514869883656502,
-0.02545052208006382,
-0.02173112891614437,
-0.022260865196585655,
0.003926816396415234,
0.034... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.