id stringlengths 7 10 | title stringlengths 8 354 | content stringlengths 91 4.1k | contents stringlengths 164 4.24k | embedding listlengths 384 384 |
|---|---|---|---|---|
PMID:11096 | The fate of ACTH released from rat anterior pituitary into the incubation medium in vitro: enzymatic degradation and acid activation. | The bioactivity of ACTH released from isolated rat anterior pituitary glands into the incubation medium was determined. After the pituitaries were removed, ACTH activity in the medium decreased exponentially during further incubation at 37degreesC. The loss of ACTH activity was temperature- and pH-dependent and inhibit... | The fate of ACTH released from rat anterior pituitary into the incubation medium in vitro: enzymatic degradation and acid activation. The bioactivity of ACTH released from isolated rat anterior pituitary glands into the incubation medium was determined. After the pituitaries were removed, ACTH activity in the medium de... | [
0.01743450202047825,
-0.005307591054588556,
-0.03939484804868698,
0.014620914123952389,
0.018039645627141,
0.0029417648911476135,
0.07325420528650284,
0.0007542076637037098,
-0.04976261779665947,
-0.01224598940461874,
-0.027728376910090446,
-0.01874115690588951,
0.005131923593580723,
0.075... |
PMID:11097 | Ferredoxin from a red alga, Porphyra umbilicalis. | A plant-algal type ferredoxin was isolated from the red alga, Porphyra umbilicalis. In its oxidised form the ferredoxin had absorption maxima at 277, (281), 323, 420 and 462 nm. Two atoms each of non-haem iron and labile sulphur were present per molecule protein. The midpoint potential of the protein was -400 mV and it... | Ferredoxin from a red alga, Porphyra umbilicalis. A plant-algal type ferredoxin was isolated from the red alga, Porphyra umbilicalis. In its oxidised form the ferredoxin had absorption maxima at 277, (281), 323, 420 and 462 nm. Two atoms each of non-haem iron and labile sulphur were present per molecule protein. The mi... | [
-0.060272302478551865,
-0.007325839251279831,
-0.0731106624007225,
0.033373717218637466,
0.009627939201891422,
-0.003551263129338622,
0.017070364207029343,
0.00032952846959233284,
-0.07533671706914902,
-0.00308770639821887,
0.0011259957682341337,
-0.0914849042892456,
-0.014860574156045914,
... |
PMID:11098 | The antigen-inexperienced thymic suppressor cells: a class of lymphocytes in the young chicken thymus that inhibits antibody production and cell-mediated immune responses. | Transfer of thymus cells from young chickens in combination with a light whole body irradiation (360 R) was found to suppress the rejection of skin grafts across strong histocompatibility (B) differences. On the average, the suppressed animals also showed decreased serum hemagglutinin titers against erythrocytes of the... | The antigen-inexperienced thymic suppressor cells: a class of lymphocytes in the young chicken thymus that inhibits antibody production and cell-mediated immune responses. Transfer of thymus cells from young chickens in combination with a light whole body irradiation (360 R) was found to suppress the rejection of skin ... | [
0.007957474328577518,
0.005810359958559275,
-0.04435267299413681,
0.06001090630888939,
0.02843971736729145,
-0.02521437034010887,
0.08165194094181061,
0.07246381789445877,
-0.023152949288487434,
-0.027892690151929855,
0.006201240234076977,
-0.09705676138401031,
0.02413671649992466,
-0.0329... |
PMID:11099 | Inhibition of T cell activity in vivo: a test model for quantitative evaluation. | A test model is presented which, in comparison with the conventional models of skin transplantation or graft-versus-host (GvH) reaction in mice, permits a more sensitive quantitative evaluation of T cell inhibition in vivo. Prospective donors (type AA) are immunized with prospective recipient material (type AB); the re... | Inhibition of T cell activity in vivo: a test model for quantitative evaluation. A test model is presented which, in comparison with the conventional models of skin transplantation or graft-versus-host (GvH) reaction in mice, permits a more sensitive quantitative evaluation of T cell inhibition in vivo. Prospective don... | [
-0.0546182356774807,
0.046356428414583206,
0.003713633632287383,
0.05834415927529335,
-0.0105320755392313,
-0.008336161263287067,
0.07759170234203339,
0.07611561566591263,
-0.03960524871945381,
-0.010164671577513218,
0.026890339329838753,
-0.04801530763506889,
0.005748780444264412,
0.00756... |
PMID:11100 | Antibody response to phosphorylcholine in vitro. II. Analysis of T-dependent and T-independent responses. | Spleen cells from BALB/c mice primed with keyhole limpet hemocyanin (KLH), were stimulated with heat-killed vaccine of rough Pneumococcus pneumoniae R36A (Pn) and/or phosphorylcholine (PC)-coupled KLH to induce an anti-PC response in vitro. The response to PC-KLH was found to be T-dependent while it is T-independent to... | Antibody response to phosphorylcholine in vitro. II. Analysis of T-dependent and T-independent responses. Spleen cells from BALB/c mice primed with keyhole limpet hemocyanin (KLH), were stimulated with heat-killed vaccine of rough Pneumococcus pneumoniae R36A (Pn) and/or phosphorylcholine (PC)-coupled KLH to induce an ... | [
-0.0766492486000061,
0.038066036999225616,
-0.03240719437599182,
0.04315778985619545,
0.013285323046147823,
-0.03382349759340286,
0.0792350023984909,
0.02233046479523182,
-0.030830074101686478,
-0.014001254923641682,
-0.005608470179140568,
-0.05075304955244064,
0.021328900009393692,
-0.021... |
PMID:11101 | Mechanisms by which hapten conjugates of pneumococcal polysaccharide interfere with the challenge of anti-hapten memory cells. | Incubation of trinitrophenylated hemocyanin (TNP-KLH)-primed spleen cells with microgram amounts of 2,4-dinitrophenyl (DNP) or 2,4,6-trinitrophenyl (TNP) conjugates of pneumococcal polysaccharide type 3 (SIII) for as little as 5 min at 4 degrees C results in a specific "block" of the 19 S and 7 S adoptive memory respon... | Mechanisms by which hapten conjugates of pneumococcal polysaccharide interfere with the challenge of anti-hapten memory cells. Incubation of trinitrophenylated hemocyanin (TNP-KLH)-primed spleen cells with microgram amounts of 2,4-dinitrophenyl (DNP) or 2,4,6-trinitrophenyl (TNP) conjugates of pneumococcal polysacchari... | [
-0.10162685811519623,
0.012194831855595112,
-0.04025410860776901,
0.021795744076371193,
0.024351203814148903,
-0.005798086524009705,
0.060378216207027435,
0.06138448417186737,
-0.04212932288646698,
-0.010863535106182098,
0.02599406987428665,
-0.03411364555358887,
0.0575420968234539,
0.0043... |
PMID:11102 | Suprression of local graft-versus-host reactions by mouse fetal and newborn spleen cells. | Fetal splenic but not thymic lymphocytes significantly reduce the ability of parenteral adult spleen cells to elicit local graft-versus-host reactions in F1 recipients. This suppressive activity wanes early after birth. There is no requirement for histo compatibility between reacting and suppressor cells. | Suprression of local graft-versus-host reactions by mouse fetal and newborn spleen cells. Fetal splenic but not thymic lymphocytes significantly reduce the ability of parenteral adult spleen cells to elicit local graft-versus-host reactions in F1 recipients. This suppressive activity wanes early after birth. There is n... | [
-0.030043961480259895,
0.010422947816550732,
-0.006088340654969215,
0.039599932730197906,
0.0037388382479548454,
-0.011079743504524231,
0.08087030798196793,
0.09902127087116241,
-0.04791511222720146,
-0.003991293255239725,
-0.005380363203585148,
-0.014497822150588036,
-0.014084570109844208,
... |
PMID:11103 | In vitro studies on smooth muscle of the human renal pelvis. | Isolated segments of human renal pelvis were studied by an isometric technique. Increases in tension following the addition of adrenaline, noradrenaline and phenylephrine were shown to be mediated via alpha-adrenoceptors. Similar responses to acetylcholine were demonstrated to be due to muscarinic receptor stimulation.... | In vitro studies on smooth muscle of the human renal pelvis. Isolated segments of human renal pelvis were studied by an isometric technique. Increases in tension following the addition of adrenaline, noradrenaline and phenylephrine were shown to be mediated via alpha-adrenoceptors. Similar responses to acetylcholine we... | [
-0.004311288706958294,
0.002085280604660511,
0.03156222030520439,
0.045328591018915176,
-0.0707128718495369,
-0.01577066071331501,
0.06433125585317612,
0.053518060594797134,
-0.0017194467363879085,
-0.02952476590871811,
-0.004618105944246054,
-0.022119494155049324,
-0.036839768290519714,
0... |
PMID:11104 | Differential response control by isopropamide: a peripherally induced discriminative cue. | The peripherally acting anticholinergic drug isopropamide (0.02 mg/kg s.c.) is shown to produce a discriminative stimulus complex in rats. In rats trained to discriminate isopropamide from saline, dexetimide and methylscopolamine were generalized with isopropamide treatment. The results indicate that drug discriminatio... | Differential response control by isopropamide: a peripherally induced discriminative cue. The peripherally acting anticholinergic drug isopropamide (0.02 mg/kg s.c.) is shown to produce a discriminative stimulus complex in rats. In rats trained to discriminate isopropamide from saline, dexetimide and methylscopolamine ... | [
0.0036342411767691374,
0.020635994151234627,
-0.027421120554208755,
0.03865213319659233,
-0.0033493919763714075,
0.03694998472929001,
0.09381107240915298,
0.05750395730137825,
-0.06074126809835434,
-0.02742564119398594,
0.017106398940086365,
0.04160917177796364,
0.007229789160192013,
0.079... |
PMID:11105 | Antiarrhythmic action of a new beta-adrenergic blocking agent, 6-(2-hydroxy-3-isopropylaminopropyloxy)-benzothiazole succinate (KF-577), compared with that of propranolol. | The antiarrhythmic activity of a new beta-adrenergic blocking agent, 6-(2-hydroxy-3-isopropylaminopropyloxy)-benzothiazole succinate (KF-577), was compared with that of propranolol. KF-577 antagonized ouabain-induced arrhythmias in normal and bilaterally vagotomized guinea pigs; its antagonistic activity was equal to t... | Antiarrhythmic action of a new beta-adrenergic blocking agent, 6-(2-hydroxy-3-isopropylaminopropyloxy)-benzothiazole succinate (KF-577), compared with that of propranolol. The antiarrhythmic activity of a new beta-adrenergic blocking agent, 6-(2-hydroxy-3-isopropylaminopropyloxy)-benzothiazole succinate (KF-577), was c... | [
-0.09393079578876495,
-0.020073145627975464,
-0.05672980844974518,
0.035939157009124756,
0.05406125262379646,
-0.0018108481308445334,
-0.02974461391568184,
0.014634563587605953,
-0.041274115443229675,
-0.042357563972473145,
-0.016896530985832214,
-0.03644997626543045,
-0.0126444511115551,
... |
PMID:11106 | Effects of drugs on the formation of homovanillic acid in the rat retina. | Homovanillic acid (HVA) levels were measured in the eye and the corpus striatum of rats under normal conditions and after different drug treatments. Neuroleptic agents such as clozapine, cis-flupenthixol and haloperidol induced comparable increases in HVA levels, whereas the non-neuroleptic trans-isomer of flupenthixol... | Effects of drugs on the formation of homovanillic acid in the rat retina. Homovanillic acid (HVA) levels were measured in the eye and the corpus striatum of rats under normal conditions and after different drug treatments. Neuroleptic agents such as clozapine, cis-flupenthixol and haloperidol induced comparable increas... | [
-0.007223438937216997,
-0.00890286173671484,
-0.004866475705057383,
0.03100774809718132,
0.006072430405765772,
0.06215885654091835,
0.0631881132721901,
0.056448403745889664,
-0.03324078768491745,
-0.03405363857746124,
0.02401917614042759,
-0.034369174391031265,
-0.004462476819753647,
0.059... |
PMID:11107 | Relationship between the prevention of rat gastric erosions and the inhibition of acid secretion by prostaglandins. | The formation of gastric mucosal erosions induced by indomethacin in the rat was inhibited in a time- and dose-dependent manner by antisecretory prostaglandins, the methyl analogues of PGE2 being 400 times as active as the parent prostaglandin. PGA2, a methyl analogue of PGF2alpha and the H2-receptor antagonist metiami... | Relationship between the prevention of rat gastric erosions and the inhibition of acid secretion by prostaglandins. The formation of gastric mucosal erosions induced by indomethacin in the rat was inhibited in a time- and dose-dependent manner by antisecretory prostaglandins, the methyl analogues of PGE2 being 400 time... | [
-0.025713231414556503,
-0.018464354798197746,
-0.012542125768959522,
0.04697940871119499,
-0.04848818480968475,
0.005325742065906525,
0.05010797828435898,
-0.0007933141314424574,
-0.057594042271375656,
-0.03622196614742279,
-0.008430179208517075,
-0.09921228885650635,
0.03375173360109329,
... |
PMID:11108 | Centrally induced reduction in sympathetic tone-a postsynaptic alpha-adrenoceptor-stimulating action of imidazolines. | Naphazoline or oxymetazoline (both 30 mug/kg) were injected into the cisterna magna of anaesthetized cats and reduced blood pressure, heart rate and the electrical discharge rate of small fibre bundles of the preganglionic sympathetic splanchnic nerve. Cats were depleted of endogenous noradrenaline by pretreatment with... | Centrally induced reduction in sympathetic tone-a postsynaptic alpha-adrenoceptor-stimulating action of imidazolines. Naphazoline or oxymetazoline (both 30 mug/kg) were injected into the cisterna magna of anaesthetized cats and reduced blood pressure, heart rate and the electrical discharge rate of small fibre bundles ... | [
-0.022541631013154984,
0.02574165165424347,
-0.0059157125651836395,
0.032768186181783676,
-0.0040503269992768764,
0.002232530154287815,
0.019384771585464478,
0.07805795222520828,
-0.01890641264617443,
-0.04433164745569229,
-0.0070114582777023315,
-0.028318073600530624,
0.0008862078539095819,... |
PMID:11109 | Contribution of granulocytopenia to endotoxin sensitivity of mice irradiated or undergoing graft-versus-host reaction. | Animals compromised by irradiation or graft-versus-host reaction (GVHR) are highly sensitive to endotoxin (ET). In order to determine the causes of the increased sensitivity of compromised mice, we studied alterations of hepatic (central) and bloodborne (peripheral) ET clearance processes. We observed that increased se... | Contribution of granulocytopenia to endotoxin sensitivity of mice irradiated or undergoing graft-versus-host reaction. Animals compromised by irradiation or graft-versus-host reaction (GVHR) are highly sensitive to endotoxin (ET). In order to determine the causes of the increased sensitivity of compromised mice, we stu... | [
-0.06431104242801666,
-0.003637780202552676,
0.010079941712319851,
0.015140790492296219,
0.05521225929260254,
-0.0387960746884346,
0.09138483554124832,
0.10532090067863464,
-0.06626627594232559,
-0.0029821309726685286,
0.009142618626356125,
-0.023824522271752357,
0.02313896268606186,
0.028... |
PMID:11110 | Mitigation of Graft-versus-host disease in mice with xenogeneic antithymocyte serum and complement. | In vitro treatment of parental C57BL/6 lymphohematopoietic cell grafts with unabsorbed guinea pig anti-mouse thymocyte serum (ATS) and guinea pig complement (GPC), prior to inoculation into lethally irradiated B6D2F hybrid hosts, has proven to be of value in terms of mitigating graft-versus-host disease (GvHD). However... | Mitigation of Graft-versus-host disease in mice with xenogeneic antithymocyte serum and complement. In vitro treatment of parental C57BL/6 lymphohematopoietic cell grafts with unabsorbed guinea pig anti-mouse thymocyte serum (ATS) and guinea pig complement (GPC), prior to inoculation into lethally irradiated B6D2F hybr... | [
-0.028478635475039482,
0.04194009304046631,
0.016304081305861473,
0.00681863259524107,
0.01989147812128067,
0.010492254979908466,
0.046598248183727264,
0.06851712614297867,
-0.07834145426750183,
-0.012051713652908802,
0.01828411966562271,
-0.06024762615561485,
-0.016633031889796257,
-0.026... |
PMID:11111 | Acid mucopolysaccharides in fibroblast cultures. 1. Influence of cell density, pH-value and lactate concentration on the MPS distribution pattern. | From cells and culture media of embryonic rat fibroblasts (1st subculture) the acid mucopolysaccharides were isolated and fractionated. The per cent calculation of the 6 fractions was based on the content of glucuronic acid. The cultures were maintained as follows: 0.5 X 10(6) to 3 X 10(6) cells were examined in Demete... | Acid mucopolysaccharides in fibroblast cultures. 1. Influence of cell density, pH-value and lactate concentration on the MPS distribution pattern. From cells and culture media of embryonic rat fibroblasts (1st subculture) the acid mucopolysaccharides were isolated and fractionated. The per cent calculation of the 6 fra... | [
-0.007154995109885931,
-0.015036330558359623,
0.009104762226343155,
-0.0031867579091340303,
-0.01694120280444622,
-0.004623287357389927,
-0.0018087695352733135,
-0.035275787115097046,
-0.027980338782072067,
-0.02315603196620941,
0.060636505484580994,
-0.07595201581716537,
0.03032383508980274... |
PMID:11112 | Acid mucopolysaccharides in fibroblast cultures. 2. 35S-sulfate incorporation kinetics in dependence on pH-value and cell density. | Cultures of embryonic rat fibroblasts were incubated with 35S-sulfate at pH 6.6 and 7.4 (Eagle basal medium plus HEPES buffer) for 12 to 48 hours. The acid mucopolysaccharides were isolated and fractionated after the method of SVEJCAR and ROBERTSON. Sulfate incorporation was determined by liquid scintillation counting. | Acid mucopolysaccharides in fibroblast cultures. 2. 35S-sulfate incorporation kinetics in dependence on pH-value and cell density. Cultures of embryonic rat fibroblasts were incubated with 35S-sulfate at pH 6.6 and 7.4 (Eagle basal medium plus HEPES buffer) for 12 to 48 hours. The acid mucopolysaccharides were isolated... | [
-0.034833092242479324,
-0.005222537089139223,
-0.025742975994944572,
-0.018628539517521858,
-0.04030383378267288,
0.03251025080680847,
-0.0012748638400807977,
-0.029296789318323135,
-0.03351835906505585,
-0.016273844987154007,
0.07689610868692398,
-0.10535833984613419,
0.003540900768712163,
... |
PMID:11114 | Allantoinase in the marine polychaete Eudistylia vancouveri. | Allantoinase, an enzyme in the purine-urea cycle, was found in Eudistylia vancouveri (Polychaeta). The enzyme had a pH optimum at 7.6. The Km was 0.012 M allantoin, and the Arrhenius energy of activation was 12.6 to 14.6 kcal/mol. | Allantoinase in the marine polychaete Eudistylia vancouveri. Allantoinase, an enzyme in the purine-urea cycle, was found in Eudistylia vancouveri (Polychaeta). The enzyme had a pH optimum at 7.6. The Km was 0.012 M allantoin, and the Arrhenius energy of activation was 12.6 to 14.6 kcal/mol. | [
-0.08914199471473694,
-0.0843103900551796,
-0.032099563628435135,
0.04000616818666458,
-0.013043137267231941,
-0.04072567820549011,
0.035750336945056915,
0.04884094372391701,
-0.0436188280582428,
0.022262483835220337,
0.08697452396154404,
-0.08407887071371078,
-0.008874790742993355,
0.0204... |
PMID:11116 | Influence of the trypsin activity by the side chain of arginine homologues. | The N-alpha-tosyl-p-nitroanilides of homoarginine and of the two shorter arginine homologues were synthesized. These compounds behave as specific, chromogenic substrates for trypsin. | Influence of the trypsin activity by the side chain of arginine homologues. The N-alpha-tosyl-p-nitroanilides of homoarginine and of the two shorter arginine homologues were synthesized. These compounds behave as specific, chromogenic substrates for trypsin. | [
-0.048772551119327545,
0.015810051932930946,
-0.019603973254561424,
-0.02183721959590912,
-0.05152186006307602,
0.0380554124712944,
0.026930304244160652,
0.006347897462546825,
-0.049677833914756775,
-0.023913580924272537,
-0.013314646668732166,
-0.04670652374625206,
-0.013629402033984661,
... |
PMID:11117 | Beta-adrenergic receptors in rat myocardium: direct detection by a new fluorescent beta-blocker. | A new fluorescent beta-blocker, 9-amino-acridin propranolol (9-AAP), was administered i.v. to rats. Multiple fluorescent 9-AAP binding sites were observed on cardiac muscle cells in frozen sections. Intensity and density of cardiac 9-AAP fluorescence were markedly reduced following pretreatment with (+/-)- and (-)-prop... | Beta-adrenergic receptors in rat myocardium: direct detection by a new fluorescent beta-blocker. A new fluorescent beta-blocker, 9-amino-acridin propranolol (9-AAP), was administered i.v. to rats. Multiple fluorescent 9-AAP binding sites were observed on cardiac muscle cells in frozen sections. Intensity and density of... | [
-0.06228775531053543,
-0.014396333135664463,
-0.050852224230766296,
0.00784252304583788,
0.016726354137063026,
0.016585135832428932,
0.04420790448784828,
0.020552651956677437,
-0.03464217111468315,
-0.04383658617734909,
0.024074304848909378,
-0.015482618473470211,
-0.044740527868270874,
0.... |
PMID:11118 | Histamine-induced hypotension modified by H1 and H2 antagonists in the monkey (Macaca mulatta). | Blocking H2 receptors with burimamide in the dose used (20 mg/kg) approximately doubles the amount of histamine needed to produce the same effect as seen when H1 antagonists (chlorpheniramine or mepyramine) are used alone. The Kz ratios for chlorpheniramine-chlorpheniramine plus burimamide are 117-204 and for mepyramin... | Histamine-induced hypotension modified by H1 and H2 antagonists in the monkey (Macaca mulatta). Blocking H2 receptors with burimamide in the dose used (20 mg/kg) approximately doubles the amount of histamine needed to produce the same effect as seen when H1 antagonists (chlorpheniramine or mepyramine) are used alone. T... | [
-0.03884788975119591,
0.018755296245217323,
-0.010691107250750065,
0.01685745269060135,
-0.04548073559999466,
-0.014030929654836655,
0.06943008303642273,
0.05693604052066803,
-0.029296910390257835,
-0.009768270887434483,
-0.028987040743231773,
-0.07230426371097565,
0.005909244064241648,
0.... |
PMID:11119 | The oxygen-linked hydrogen ion binding (the Haldane coefficient) of bovine hemoglobin. | The Haldane coefficient (the amount of the oxygen-linked hydrogen ion binding of hemoglobin) was determined in bovine erythrolysate (Hb concentration equals 13.5 mM) by means of the differential titration method with varying PCO2 from 0 to 74 mm Hg and pH from 6.0 to 8.5 at 37 degrees C. The maximum value of the coeffi... | The oxygen-linked hydrogen ion binding (the Haldane coefficient) of bovine hemoglobin. The Haldane coefficient (the amount of the oxygen-linked hydrogen ion binding of hemoglobin) was determined in bovine erythrolysate (Hb concentration equals 13.5 mM) by means of the differential titration method with varying PCO2 fro... | [
-0.06860839575529099,
0.061994485557079315,
-0.035649824887514114,
-0.021977905184030533,
0.053460244089365005,
-0.059127844870090485,
0.09466113895177841,
0.02760220319032669,
-0.02367187663912773,
0.03334999457001686,
0.016912654042243958,
-0.11929788440465927,
-0.0067094312980771065,
0.... |
PMID:11120 | Activation of sustained sympathetic vasodilatation in dog by spinal cord stimulation. | Electrical stimulation in lateral sites of the upper cervical spinal cord evoked vasodilatation after adrenergic blockade. Sympathetic fibres mediating sustained vasodilatation were shown to be separate from adrenergic sympathetic fibres since the adrenergic vasoconstrictor response in the paw evoked by vasomotor stimu... | Activation of sustained sympathetic vasodilatation in dog by spinal cord stimulation. Electrical stimulation in lateral sites of the upper cervical spinal cord evoked vasodilatation after adrenergic blockade. Sympathetic fibres mediating sustained vasodilatation were shown to be separate from adrenergic sympathetic fib... | [
-0.018790781497955322,
0.014205548912286758,
-0.02277032472193241,
0.05456361919641495,
-0.0029482918325811625,
0.01808403618633747,
0.012321162037551403,
0.015865860506892204,
0.039406668394804,
-0.0402054600417614,
0.008781182579696178,
-0.053585123270750046,
-0.003075086511671543,
0.031... |
PMID:11121 | Effects of morphine administration on cerebellar guanosine 3',5'-monophosphate. | An increase in mouse cerebellar C-GMP levels during acute morphine treatment was observed, which was possibly related to the decrease in C-GMP phosphodiesterase levels also observed in acute treatment. Chronic treatment lowered C-GMP levels as did abrupt withdrawal without naloxone. | Effects of morphine administration on cerebellar guanosine 3',5'-monophosphate. An increase in mouse cerebellar C-GMP levels during acute morphine treatment was observed, which was possibly related to the decrease in C-GMP phosphodiesterase levels also observed in acute treatment. Chronic treatment lowered C-GMP levels... | [
-0.018073128536343575,
0.0063397083431482315,
0.016174079850316048,
-0.000550679222214967,
-0.007631109561771154,
0.041132908314466476,
0.06017497554421425,
0.06942179799079895,
-0.06858059018850327,
-0.026923391968011856,
-0.0007459362968802452,
0.018348341807723045,
-0.02245812863111496,
... |
PMID:11122 | [Effect of liver damage by thioacetamide on microsomal aromatization of testosterone in rats (author's transl)]. | Rat liver microsomes, NADPH-regenerating system, and 1beta, 2beta-3H-testosterone have been incubated in vitro. The loss of tritium from the steroid, associated with aromatization of testosterone, was linear with time for 20 min and required NADPH. Pre-treatment of the rats with thioacetamide raised the liberation of t... | [Effect of liver damage by thioacetamide on microsomal aromatization of testosterone in rats (author's transl)]. Rat liver microsomes, NADPH-regenerating system, and 1beta, 2beta-3H-testosterone have been incubated in vitro. The loss of tritium from the steroid, associated with aromatization of testosterone, was linear... | [
0.014647658914327621,
0.00001077969773177756,
0.0054287295788526535,
-0.021561745554208755,
0.03400199115276337,
0.015227306634187698,
0.06496252119541168,
-0.015653301030397415,
-0.06566209346055984,
-0.05889488384127617,
0.03887983784079552,
-0.05089639872312546,
0.09803856909275055,
-0.... |
PMID:11136 | Reduction of the graft-versus-host reactivity of mouse and rat spleen cells by 5alpha-androstane-3,17-dione. | The local graft-versus-host reaction as evaluated by the popliteal lymph node enlargement was used for studying the immunosuppressive potency of placental steroid 5alpha-androstane-3,17-dione. Spleen cells from virgin female mice and rats injected subcutaneously with this steroid compound produced in appropriate F1 rec... | Reduction of the graft-versus-host reactivity of mouse and rat spleen cells by 5alpha-androstane-3,17-dione. The local graft-versus-host reaction as evaluated by the popliteal lymph node enlargement was used for studying the immunosuppressive potency of placental steroid 5alpha-androstane-3,17-dione. Spleen cells from ... | [
-0.021004825830459595,
0.0109330452978611,
-0.0033289482817053795,
0.006109636276960373,
0.002460279269143939,
-0.018530292436480522,
0.05356643721461296,
0.08299358189105988,
-0.07262113690376282,
-0.05796295776963234,
0.007727761287242174,
-0.03065364621579647,
0.021441303193569183,
-0.0... |
PMID:11137 | The sensitivity of chromatin from thymuses and spleens of irradiated mice to alkaline solutions. | Increasing amounts of DNA and proteins are released from the suspensions of chromatin from thymuses and spleens of irradiated mice (6 hours after 600R whole-body) by the action of alkaline solutions (pH 8-10) at physiological ionic strengths. The suspension of chromatin from normal tissues releases in this pH range onl... | The sensitivity of chromatin from thymuses and spleens of irradiated mice to alkaline solutions. Increasing amounts of DNA and proteins are released from the suspensions of chromatin from thymuses and spleens of irradiated mice (6 hours after 600R whole-body) by the action of alkaline solutions (pH 8-10) at physiologic... | [
-0.031932927668094635,
0.018257809802889824,
0.02188223786652088,
-0.014596416614949703,
-0.009848284535109997,
-0.058797113597393036,
0.07354829460382462,
0.03087753802537918,
-0.02342453971505165,
0.01805739291012287,
-0.00865355134010315,
-0.06579001247882843,
0.0014477170770987868,
0.0... |
PMID:11138 | Some biological properties of mouse spleen cells fractionated by the adherence of Sephadex G 25 and glass bead columns. | The possibilities of separation of haemopoietic cells from lymphocytes capable of eliciting the graft-versus-host reaction through column chromatography were investigated. Strain-A mouse spleen cells were fractionated into the adherent and non-adherent fraction on Sephadex G-25, glass bead columns and glass beads coate... | Some biological properties of mouse spleen cells fractionated by the adherence of Sephadex G 25 and glass bead columns. The possibilities of separation of haemopoietic cells from lymphocytes capable of eliciting the graft-versus-host reaction through column chromatography were investigated. Strain-A mouse spleen cells ... | [
-0.06534836441278458,
0.009472428821027279,
-0.005177776329219341,
-0.030960841104388237,
0.011167880147695541,
-0.03450411930680275,
0.07289247214794159,
0.07267671078443527,
-0.046788278967142105,
0.04420476034283638,
0.009227098897099495,
-0.04904092103242874,
-0.002704810816794634,
0.0... |
PMID:11140 | Dopamine as a possible neurotransmitter in gastric relaxation. | In dogs with gastric fistulas, intragastric pressure was measured with a flaccid ballon containing 500 ml of water. Graded doses of dopamine caused graded decreases in intragastric pressure. The effect was blocked by pimozide or by metoclopramide but was not significantly affected by phenoxybenzamine, propranolol, guan... | Dopamine as a possible neurotransmitter in gastric relaxation. In dogs with gastric fistulas, intragastric pressure was measured with a flaccid ballon containing 500 ml of water. Graded doses of dopamine caused graded decreases in intragastric pressure. The effect was blocked by pimozide or by metoclopramide but was no... | [
-0.02020949311554432,
-0.012801849283277988,
0.03380495682358742,
0.06273054331541061,
-0.043647199869155884,
0.04086485877633095,
0.06285424530506134,
-0.03215468302369118,
-0.00504197645932436,
-0.08075296133756638,
-0.033057209104299545,
-0.06292462348937988,
-0.030544018372893333,
0.08... |
PMID:11141 | Inhibition of intestinal iron absorption by laundry starch. | The pathogenesis of iron deficiency anemia associated with amylophagia is usually attributed to dietary iron lack. However, large quantities of starch may inhibit intestinal iron absorption. Accordingly, studies were carried out to determine the effect of laundry starch on the intestinal absorption of inorganic and hem... | Inhibition of intestinal iron absorption by laundry starch. The pathogenesis of iron deficiency anemia associated with amylophagia is usually attributed to dietary iron lack. However, large quantities of starch may inhibit intestinal iron absorption. Accordingly, studies were carried out to determine the effect of laun... | [
-0.014719822444021702,
0.02153773233294487,
-0.014085635542869568,
0.00975959375500679,
0.01726992055773735,
-0.024647792801260948,
0.09063201397657394,
0.04752030596137047,
-0.09717301279306412,
-0.06382527202367783,
0.057065777480602264,
-0.07458455115556717,
0.019426092505455017,
0.0061... |
PMID:11142 | Effect of serotonin on water and electrolyte transport in the in vivo rabbit small intestine. | The influence of intravenously administered serotonin on water and electrolyte fluxes in the in vivo rabbit jejunum and ileum was examined. Animals were divided into four groups: (1) those receiving saline intravenously while a glucose-free isotonic saline solution perfused the jejunum and ileum; (2) serotonin given in... | Effect of serotonin on water and electrolyte transport in the in vivo rabbit small intestine. The influence of intravenously administered serotonin on water and electrolyte fluxes in the in vivo rabbit jejunum and ileum was examined. Animals were divided into four groups: (1) those receiving saline intravenously while ... | [
-0.013829727657139301,
-0.0552983433008194,
0.003561883931979537,
0.04776209220290184,
0.012706957757472992,
-0.0228154044598341,
0.046360332518815994,
0.03879423439502716,
-0.013839196413755417,
-0.07240723818540573,
-0.01901283487677574,
-0.08985891938209534,
-0.01113001350313425,
0.0195... |
PMID:11144 | Lower esophageal sphincter response to oral administration of cimetidine in normal subjects. | Anithistamines that specifically block the gastric and secretory action of histamine have recently been developed. One of these H2-receptor blockers, metiamide, has been found to increase lower esophageal sphincter (LES) pressure in the opossum. Because of reported agranulocytosis with metiamide, another H2-receptor bl... | Lower esophageal sphincter response to oral administration of cimetidine in normal subjects. Anithistamines that specifically block the gastric and secretory action of histamine have recently been developed. One of these H2-receptor blockers, metiamide, has been found to increase lower esophageal sphincter (LES) pressu... | [
0.0013060476630926132,
-0.02951136603951454,
0.020244350656867027,
0.05002317950129509,
-0.047242097556591034,
-0.026917481794953346,
0.07395334541797638,
0.04118405282497406,
-0.018326634541153908,
-0.030009549111127853,
0.030392305925488472,
-0.022392457351088524,
-0.0014133488293737173,
... |
PMID:11145 | The role of histamine receptors in the pathophysiology of gastric mucosal damage. | In four canine Heidenhain pouches the net fluxes of H+ and Na+ have been examined before, during, and after instillation of sodium taurocholate into the pouch. These experiments were conducted in animals given H1 (mepyramine maleate) and H2 (metiamide) histamine antagonists, alone and in combination. Control experiment... | The role of histamine receptors in the pathophysiology of gastric mucosal damage. In four canine Heidenhain pouches the net fluxes of H+ and Na+ have been examined before, during, and after instillation of sodium taurocholate into the pouch. These experiments were conducted in animals given H1 (mepyramine maleate) and ... | [
-0.019373511895537376,
-0.035407811403274536,
0.01830829679965973,
0.05565657466650009,
-0.02316899783909321,
-0.016032030805945396,
0.07478239387273788,
-0.004165816120803356,
-0.04606908559799194,
-0.052869413048028946,
-0.0010994459735229611,
-0.1079065352678299,
0.008176734670996666,
0... |
PMID:11146 | Properties of gastric antrum. III. Selectivity and modification of shunt conductance. | The permselectivity of the paracellular pathway of amphibian (Necturus and bullfrog) antrum was investigated with respect to intracationic selectivity and the K+ and Cl- permeability ratio as a function of mucosal pH. The intracationic selectivity sequence was Rb+ greater than K+ greater than Cs+ greater than Na+ great... | Properties of gastric antrum. III. Selectivity and modification of shunt conductance. The permselectivity of the paracellular pathway of amphibian (Necturus and bullfrog) antrum was investigated with respect to intracationic selectivity and the K+ and Cl- permeability ratio as a function of mucosal pH. The intracationi... | [
-0.03813425451517105,
-0.038675785064697266,
0.0010476902825757861,
0.02022569067776203,
0.007899525575339794,
-0.009408440440893173,
0.0550333671271801,
0.025242073461413383,
-0.03543931618332863,
-0.043737370520830154,
-0.009295542724430561,
-0.11608026921749115,
-0.012638880871236324,
0... |
PMID:11147 | Effect of fundusectomy on serum and antral gastrin levels in rats. | In adult male rats, fundusectomy decreased acid secretion but significantly increased total antral gastrin and both fasting and food-stimulated serum gastrin levels. The rise in fasting serum gastrin could be inhibited by antral acidification, suggesting that decreased acidity caused postfundusectomy hypergastrinemia. ... | Effect of fundusectomy on serum and antral gastrin levels in rats. In adult male rats, fundusectomy decreased acid secretion but significantly increased total antral gastrin and both fasting and food-stimulated serum gastrin levels. The rise in fasting serum gastrin could be inhibited by antral acidification, suggestin... | [
0.036369651556015015,
0.021827002987265587,
0.01250558439642191,
0.050670746713876724,
0.07135648280382156,
0.0002204452466685325,
0.008765646256506443,
0.03485485538840294,
-0.05855429545044899,
-0.09048537909984589,
0.03281790390610695,
-0.05459660291671753,
0.0001654538355069235,
0.0626... |
PMID:11148 | Postprandial gastric, pancreatic, and biliary response to histamine H2-receptor antagonists active duodenal ulcer. | Histamine H2-receptor antagonists are potentially useful agents in duodenal ulcer and knowledge of their effect on postprandial digestive events will contribute to their clinical application. We studied the effect of 200- and 300-mg doses of cimetidine, an H2-receptor antagonist, taken with an ordinary meal, on gastric... | Postprandial gastric, pancreatic, and biliary response to histamine H2-receptor antagonists active duodenal ulcer. Histamine H2-receptor antagonists are potentially useful agents in duodenal ulcer and knowledge of their effect on postprandial digestive events will contribute to their clinical application. We studied th... | [
-0.016221072524785995,
-0.00623809639364481,
0.0035820328630506992,
0.03366149589419365,
-0.03324140980839729,
-0.03331673890352249,
0.04350525513291359,
0.06701996177434921,
-0.04671376943588257,
-0.04681846871972084,
0.012644773349165916,
-0.06925652176141739,
0.013471418060362339,
0.008... |
PMID:11149 | Isolation and characterization of four peptide hydrolases from the cytosol of rat intestinal mucosa. | The high speed supernatant fluid prepared from rat intestinal mucosa was subjected to ion-exchange chromatography on diethlaminoethyl-cellulose eluted with a linear gradient of sodium chloride (0 to 0.27 M). Assay of eluted fractions for Phe-Gly hydrolase activity revealed four distinct peaks of enzyme activity. These ... | Isolation and characterization of four peptide hydrolases from the cytosol of rat intestinal mucosa. The high speed supernatant fluid prepared from rat intestinal mucosa was subjected to ion-exchange chromatography on diethlaminoethyl-cellulose eluted with a linear gradient of sodium chloride (0 to 0.27 M). Assay of el... | [
-0.07847131043672562,
-0.024522850289940834,
-0.016825169324874878,
0.02144111506640911,
-0.0003931119863409549,
-0.09017153829336166,
0.05123427137732506,
0.020350540056824684,
-0.05181290581822395,
-0.0025955233722925186,
0.016892140731215477,
-0.04186050221323967,
-0.031486526131629944,
... |
PMID:11150 | [Characteristics of two new mutant forms of erythrocyte glucose-6-phosphate dehydrogenase: "Kirovograd" G6PD and "Zhitomir" G6PD]. | The paper comprises the description of properties of three mutant forms of glucoso-6-phosphate dehydrogenase characterized according the WHO program. Preparations of the enzymes were isolated from erythrocytes of patients with G6PD deficiency from three unrelated to one another Ashkenasi families coming from the Ukrain... | [Characteristics of two new mutant forms of erythrocyte glucose-6-phosphate dehydrogenase: "Kirovograd" G6PD and "Zhitomir" G6PD]. The paper comprises the description of properties of three mutant forms of glucoso-6-phosphate dehydrogenase characterized according the WHO program. Preparations of the enzymes were isolat... | [
-0.050744373351335526,
0.00325921387411654,
0.0410832017660141,
0.006206211633980274,
0.010921245440840721,
-0.02511495351791382,
0.01831713505089283,
0.0429743155837059,
-0.11666052043437958,
0.011948897503316402,
0.028927821666002274,
-0.026667509227991104,
-0.06576620042324066,
-0.00274... |
PMID:11151 | [Influence of the maternal effect on allogenic inhibition of hematopoietic stem cells]. | Bone marrow cells (0,5-10(6)) of female mice of CBA or C57BL strains were injected intravenously to lethally irradiated CBA, C57BL/6, (femaleCBA X maleC57BL/6)F1 and (femaleC57BL/6 X maleCBA)F1 mice. Spleen of recipients as assayed for colony count on the 9th day after bone marrow transplantation by the method of Till ... | [Influence of the maternal effect on allogenic inhibition of hematopoietic stem cells]. Bone marrow cells (0,5-10(6)) of female mice of CBA or C57BL strains were injected intravenously to lethally irradiated CBA, C57BL/6, (femaleCBA X maleC57BL/6)F1 and (femaleC57BL/6 X maleCBA)F1 mice. Spleen of recipients as assayed ... | [
-0.03934154659509659,
0.03951866924762726,
-0.04686162620782852,
-0.0301524568349123,
-0.04781902953982353,
0.016354721039533615,
0.04018054157495499,
0.07600414752960205,
-0.021892091259360313,
0.004047634545713663,
0.043340664356946945,
-0.06090802326798439,
-0.023293836042284966,
-0.028... |
PMID:11152 | Effect of size of Morris hepatoma 5123D on gamma-glutamyltranspeptidase activity in serum and urine. | Close correlation between the size of Morris hepatoma 5123D implanted in the hind limb of rat and serum gamm-glutamyltranspeptidase activity was found. The tumour implanted in both hind legs of the rat resulted in about twofold increase of the serum enzyme activity. The growth of the hepatoma resulted also in a signifi... | Effect of size of Morris hepatoma 5123D on gamma-glutamyltranspeptidase activity in serum and urine. Close correlation between the size of Morris hepatoma 5123D implanted in the hind limb of rat and serum gamm-glutamyltranspeptidase activity was found. The tumour implanted in both hind legs of the rat resulted in about... | [
-0.015689488500356674,
-0.03114175796508789,
0.035474613308906555,
-0.006361562758684158,
0.020976226776838303,
-0.012435836717486382,
0.07761720567941666,
0.0663880854845047,
-0.035264305770397186,
-0.030514363199472427,
0.0202045738697052,
0.0028632916510105133,
-0.031619131565093994,
0.... |
PMID:11153 | [Experimental anti-arrhythmic effects of a new beta-adrenergic receptor blocking agent, dl-l-(tert. butylamino)-3-[(2-propinyloxy)phenoxy]2-propanol hydrochloride (dl Kö 1400-Cl)]. | Antiarrhythmic property of a new adrenergic beta-blocking agent, dl-1-(tert.butylamino)-3[(2-propinyloxy) phenoxy]-2-propanol hydrochloride (Kö 1400-Cl) was studied, using 1) ouabain-induced arrhythmia in the guinea pig, 2) aconitine-induced arrhythmia in the rat, 3) arrhythmia induced by two-step ligation of coronary ... | [Experimental anti-arrhythmic effects of a new beta-adrenergic receptor blocking agent, dl-l-(tert. butylamino)-3-[(2-propinyloxy)phenoxy]2-propanol hydrochloride (dl Kö 1400-Cl)]. Antiarrhythmic property of a new adrenergic beta-blocking agent, dl-1-(tert.butylamino)-3[(2-propinyloxy) phenoxy]-2-propanol hydrochloride... | [
-0.09510058909654617,
-0.004276833962649107,
-0.03528634458780289,
0.05067234858870506,
0.025486843660473824,
0.018554221838712692,
-0.0030747666023671627,
0.025988735258579254,
-0.015792254358530045,
-0.05606410652399063,
-0.010008919052779675,
-0.01591554284095764,
-0.016460876911878586,
... |
PMID:11154 | Exocellular proteases of Serratia marcescens and their toxicity to larvae of Galleria mellonella. | Out of 18 strains of Serratia marcescens producing exocellular proteases the strain Serratia marcescens CCEB 415 was selected according to preliminary experiments. It could be shown that the train exhibits proteolytic activity reaching up to 10 TU per 1 ml of the culture filtrate in a medium with gelatine and peptone. ... | Exocellular proteases of Serratia marcescens and their toxicity to larvae of Galleria mellonella. Out of 18 strains of Serratia marcescens producing exocellular proteases the strain Serratia marcescens CCEB 415 was selected according to preliminary experiments. It could be shown that the train exhibits proteolytic acti... | [
-0.052796103060245514,
-0.03134346380829811,
0.005763140041381121,
0.022621335461735725,
0.01629808358848095,
-0.07106678187847137,
0.008641921915113926,
0.07273252308368683,
-0.030693136155605316,
-0.00816678162664175,
0.017793314531445503,
-0.044235195964574814,
-0.02681700699031353,
0.0... |
PMID:11158 | [Teratogenic damages of the male genital organs]. | 1. Malformations and functional disturbances of the male genitalia may be caused by teratogens. 2. A short review of the prenatal development points out the possible sites of action. 3. In animals some distinct teratogens produce typical malformation syndromo spermatogenetic cells. Cyproteronacetat, an antiandrogen, su... | [Teratogenic damages of the male genital organs]. 1. Malformations and functional disturbances of the male genitalia may be caused by teratogens. 2. A short review of the prenatal development points out the possible sites of action. 3. In animals some distinct teratogens produce typical malformation syndromo spermatoge... | [
0.032007552683353424,
0.03383921459317207,
-0.01356815081089735,
0.023698318749666214,
0.015141884796321392,
0.01697665825486183,
0.02065178006887436,
0.10067421197891235,
-0.03266065940260887,
0.008799627423286438,
-0.018062923103570938,
-0.06930223107337952,
0.052849285304546356,
0.02517... |
PMID:11162 | [Liver function in undisturbed pregnancy]. | In order to evaluate liver function during pregnancy the enzyme activities of GPT, GOT, GLDH, LDH, AP, LAP, gamma-GT and CHE were determined in 272 healthy pregnant women from the 16th week of gestation up to term. The normal range of GPT, GOT, GLDH, LDH, gamma-GT and CHE did not differ significantly from those in non-... | [Liver function in undisturbed pregnancy]. In order to evaluate liver function during pregnancy the enzyme activities of GPT, GOT, GLDH, LDH, AP, LAP, gamma-GT and CHE were determined in 272 healthy pregnant women from the 16th week of gestation up to term. The normal range of GPT, GOT, GLDH, LDH, gamma-GT and CHE did ... | [
0.07856712490320206,
0.019067829474806786,
0.01652119681239128,
0.07924963533878326,
0.00997792836278677,
0.005267776548862457,
0.10563604533672333,
0.09710883349180222,
-0.025240853428840637,
-0.03646630048751831,
-0.0391426682472229,
-0.023473186418414116,
-0.022254513576626778,
0.046696... |
PMID:11163 | [Beta receptor blocking agents in psychiatry (author's transl)]. | The effects of beta receptor blocking agents in various psychiatric indications have been investigated during the last decade. The results are summarised and discussed. A final judgement of the value of beta blocking agents within the complete psychopharmacological treatment is, at present, not yet possible. They appea... | [Beta receptor blocking agents in psychiatry (author's transl)]. The effects of beta receptor blocking agents in various psychiatric indications have been investigated during the last decade. The results are summarised and discussed. A final judgement of the value of beta blocking agents within the complete psychopharm... | [
-0.001649209181778133,
0.03440887853503227,
0.02085690014064312,
0.02493598684668541,
-0.006250043399631977,
0.05001107603311539,
0.037309903651475906,
0.030237773433327675,
-0.0031395929399877787,
-0.1147264689207077,
0.020665835589170456,
-0.003844009479507804,
0.009358730167150497,
0.06... |
PMID:11164 | [A sensitive fluorometric determination of catechol methyltransferase activity (author's transl)]. | A method for the determination of catechol-methyltransferase activity is described, based on the measurement of fluorometric intensity of 7-hydroxy-6-methoxycoumarin (scopoletin), enzymatically produced by dihydroxycoumarin in the presence of the methyl donor S-adenosylmethionine. | [A sensitive fluorometric determination of catechol methyltransferase activity (author's transl)]. A method for the determination of catechol-methyltransferase activity is described, based on the measurement of fluorometric intensity of 7-hydroxy-6-methoxycoumarin (scopoletin), enzymatically produced by dihydroxycoumar... | [
-0.057993896305561066,
-0.0183268915861845,
-0.04136492684483528,
-0.02226434275507927,
-0.006111373193562031,
0.000622037798166275,
0.058830395340919495,
0.05291496962308884,
-0.007987117394804955,
-0.04386148601770401,
-0.004851309582591057,
-0.05222753435373306,
-0.01649376191198826,
-0... |
PMID:11165 | [Detection of multiple molecular forms of the gamma-glutamyltransferase by concanavalin A affinity chromatography (author's transl)]. | The separation of several forms of gamma-glutamyl-transferase was achieved by using concanavalin A-Sepharose columns. The enzyme of the adult liver was bound totally to the lectin, whereas only 5% of the kidney enzyme and 50% of the pancreas gamma-glutamyltransferase was adsorbed by concanavalin A. Due to a higher cont... | [Detection of multiple molecular forms of the gamma-glutamyltransferase by concanavalin A affinity chromatography (author's transl)]. The separation of several forms of gamma-glutamyl-transferase was achieved by using concanavalin A-Sepharose columns. The enzyme of the adult liver was bound totally to the lectin, where... | [
-0.023827727884054184,
-0.02902773953974247,
-0.04798610135912895,
-0.0071301888674497604,
0.010292204096913338,
0.012730192393064499,
0.07713992148637772,
0.062444329261779785,
-0.07444430887699127,
-0.018083300441503525,
0.04099051281809807,
-0.05333086848258972,
-0.027572985738515854,
0... |
PMID:11166 | [Isoelectric focusing of complex protein mixtures in the nanogram range in microgels (author's transl)]. | A method is described for isolectric focusing of complex protein mixtures in 2, 5 or 10 mul capillaries. For one separation only 15- 50 ng of a protein mixture is needed. Isoelectric focusing is finished after 10 min, staining takes 20 min and destaining approximately 30 min. Using defined mixtures of Servalyt from dif... | [Isoelectric focusing of complex protein mixtures in the nanogram range in microgels (author's transl)]. A method is described for isolectric focusing of complex protein mixtures in 2, 5 or 10 mul capillaries. For one separation only 15- 50 ng of a protein mixture is needed. Isoelectric focusing is finished after 10 mi... | [
-0.05941113829612732,
0.007657979615032673,
-0.02383170835673809,
-0.026187816634774208,
-0.01643168367445469,
-0.0017638636054471135,
0.07820385694503784,
0.013627818785607815,
-0.027663754299283028,
0.010144740343093872,
0.01510874554514885,
-0.08713377267122269,
-0.0009748031152412295,
... |
PMID:11167 | Activation of snail (Helix pomatia) nervous tissue tyrosine monooxygenase by calcium in vitro. | Addition of calcium chloride to soluble preparations of tyrosine monooxygenase from snail brain appears to produce an activation of the enzyme when assayed with subsaturating concentrations of the pteridine cofactor 6 MPH4 (2-amino-4-hydroxy-6-methyltetrahydropteridine). While some increase in the activity occurs with ... | Activation of snail (Helix pomatia) nervous tissue tyrosine monooxygenase by calcium in vitro. Addition of calcium chloride to soluble preparations of tyrosine monooxygenase from snail brain appears to produce an activation of the enzyme when assayed with subsaturating concentrations of the pteridine cofactor 6 MPH4 (2... | [
-0.000979742151685059,
-0.006766038481146097,
-0.0383601039648056,
0.04143629968166351,
-0.0807933509349823,
0.010225658304989338,
0.09530311077833176,
0.034061480313539505,
-0.040432076901197433,
-0.008413937874138355,
0.03679352253675461,
-0.11474629491567612,
0.008477450348436832,
0.043... |
PMID:11168 | Extrinsic signals for monitoring the association reaction of proteins as introduced by fluorescent and non-fluorescent labels. | Two known dansyl labels (I, II) and 5-[2-(iodoacetamido)ethylamino]-1-naphthalene-sulfonic acid (III) and three new azo-dyes (IV - VI) were covalently attached to alpha-chymotrypsin and to basic pancreatic trypsin inhibitor by four different reactive groups. In order to protect the contact region of the proteins the co... | Extrinsic signals for monitoring the association reaction of proteins as introduced by fluorescent and non-fluorescent labels. Two known dansyl labels (I, II) and 5-[2-(iodoacetamido)ethylamino]-1-naphthalene-sulfonic acid (III) and three new azo-dyes (IV - VI) were covalently attached to alpha-chymotrypsin and to basi... | [
-0.06574300676584244,
-0.010178068652749062,
-0.08365996927022934,
0.023041903972625732,
0.03600554168224335,
-0.023106589913368225,
0.07011832296848297,
0.047894299030303955,
-0.020998332649469376,
-0.016462160274386406,
0.03465033322572708,
-0.05985957011580467,
0.012195398099720478,
0.0... |
PMID:11169 | Influence of various fluorescent and non-fluorescent labels on the kinetics of the complex formation of alpha-chymotrypsin with basic pancreatic trypsin inhibitor (Kunitz). | The association of alpha-chymotrypsin with basic pancreatic trypsin inhibitor was studied using extrinsic signals produced by fluorescent and nonfluorescent labels. The reactive dyes were covalently bound to the proteins in the complexed state, in which the binding region was protected. The signals were sufficiently la... | Influence of various fluorescent and non-fluorescent labels on the kinetics of the complex formation of alpha-chymotrypsin with basic pancreatic trypsin inhibitor (Kunitz). The association of alpha-chymotrypsin with basic pancreatic trypsin inhibitor was studied using extrinsic signals produced by fluorescent and nonfl... | [
-0.08391871303319931,
-0.03178873658180237,
-0.06813941895961761,
0.0033756301272660494,
-0.004805882461369038,
0.013805734924972057,
0.05977358669042587,
0.04328146204352379,
-0.022849392145872116,
-0.01183299534022808,
0.026798482984304428,
-0.04533737525343895,
0.009742614813148975,
0.0... |
PMID:11177 | Rat liver cells in culture: effect of storage, long-term culture, and transformation on some enzyme levels. | Aryl hydrocarbon hydroxylase (AHH) and tyrosine aminotransferase (TAT) activities were determined in rat liver cell lines after frozen storage, long-term culture, and transformation in vitro. Levels of AHH activity after 17 months in frozen storage were comparable to levels prior to freezing. During long-term culture t... | Rat liver cells in culture: effect of storage, long-term culture, and transformation on some enzyme levels. Aryl hydrocarbon hydroxylase (AHH) and tyrosine aminotransferase (TAT) activities were determined in rat liver cell lines after frozen storage, long-term culture, and transformation in vitro. Levels of AHH activi... | [
-0.012094738893210888,
0.033253297209739685,
-0.016440149396657944,
0.025638073682785034,
-0.024072255939245224,
-0.000051190774684073403,
0.030807752162218094,
0.018115386366844177,
-0.06609775125980377,
-0.00030870040063746274,
0.012855378910899162,
-0.06645330786705017,
0.0084585407748818... |
PMID:11178 | Synthesis of alpha subunit of human chorionic gonadotrophin by presumptive HeLa cells. | Several cell lines, originally thought to be derived from a human placenta at term but possibly HeLa-contaminated, have been studied. These cells secrete a protein indistinguishable immunochemically from the alpha subunit of chorionic gonadotropin but not the beta subunit of chorionic gonadotropin or placental lactogen... | Synthesis of alpha subunit of human chorionic gonadotrophin by presumptive HeLa cells. Several cell lines, originally thought to be derived from a human placenta at term but possibly HeLa-contaminated, have been studied. These cells secrete a protein indistinguishable immunochemically from the alpha subunit of chorioni... | [
-0.003833112306892872,
-0.009567221626639366,
-0.029435304924845695,
0.024810807779431343,
-0.03240817040205002,
-0.003358917310833931,
0.05715584009885788,
0.01761782355606556,
-0.0027425168082118034,
-0.011874270625412464,
0.0016680537955835462,
-0.09326952695846558,
-0.007755591534078121,... |
PMID:11179 | [Approach to a practical method for screening and identifying microorganism genera from urine (author's transl)]. | In this study the author reported upon a practical new system for screening and identifying the microbial agents causing urinary tract infections. This system is composed of a combination of 3 screening procedures (pH-value + nitrite-test + catalase-test) and 8 selective culture media for the purpose of genus identific... | [Approach to a practical method for screening and identifying microorganism genera from urine (author's transl)]. In this study the author reported upon a practical new system for screening and identifying the microbial agents causing urinary tract infections. This system is composed of a combination of 3 screening pro... | [
0.044754061847925186,
0.04790213331580162,
0.02738252282142639,
0.023614436388015747,
0.0842028558254242,
-0.03460031747817993,
0.026436077430844307,
0.03928520530462265,
0.015202282927930355,
0.05885547772049904,
0.01026057731360197,
-0.04294025897979736,
0.02138085477054119,
-0.005106768... |
PMID:11180 | Slow reacting substance as a preformed mediator from human lung. | Homogenates from human lung contained a preformed slow reacting substance (pSRS). The pattern of contraction on the guinea-pig ileum by pSRS was indistinguishable from that of SRS-A. The activity of pSRS could not be attributed to the presence of K+, Na+, Ca2+ and Mg2+ ions, or any prostaglandin including PGF2 or its 1... | Slow reacting substance as a preformed mediator from human lung. Homogenates from human lung contained a preformed slow reacting substance (pSRS). The pattern of contraction on the guinea-pig ileum by pSRS was indistinguishable from that of SRS-A. The activity of pSRS could not be attributed to the presence of K+, Na+,... | [
-0.06922681629657745,
0.0017846758710220456,
-0.07047314941883087,
-0.004704248160123825,
0.04429998621344566,
-0.028302224352955818,
0.06466788053512573,
0.006179419346153736,
-0.03791569545865059,
0.0034903401974588633,
-0.031781479716300964,
-0.05698021128773689,
0.019184060394763947,
0... |
PMID:11181 | Analysis of immunosuppression generated by the graft-versus-host reaction. II. Characterization of the suppression cell and its mechanism of action. | Spleen cells from (CBA X C57/BL) F1 mice undergoing graft-versus-host (GVH) reaction induced by injection of parental cells 7-14 days previously are capable of suppressing an immune response by normal or primed F1 spleen cells to chicken erythrocytes and levan in vivo and sheep erythrocytes in vitro. The cells in these... | Analysis of immunosuppression generated by the graft-versus-host reaction. II. Characterization of the suppression cell and its mechanism of action. Spleen cells from (CBA X C57/BL) F1 mice undergoing graft-versus-host (GVH) reaction induced by injection of parental cells 7-14 days previously are capable of suppressing... | [
-0.005759886931627989,
0.03699503839015961,
-0.05446678772568703,
0.026014698669314384,
0.024518270045518875,
-0.015794914215803146,
0.06388365477323532,
0.072943776845932,
-0.027810998260974884,
0.03132093325257301,
-0.013675551861524582,
-0.03838495910167694,
0.06271357834339142,
-0.0131... |
PMID:11187 | Large-scale purification and characterization of the exotoxin of Pseudomonas aeruginosa. | The exotoxin (PE) of Pseudomonas aeruginosa was purified from 50-liter cultures by a simple three-step procedure, yielding 135 mg of essentially homogeneous protein. In Ouchterlony gel diffusion, PE produces a single line which does not interact with a diphtheria toxin-antitoxin precipitin line. The protein has a molec... | Large-scale purification and characterization of the exotoxin of Pseudomonas aeruginosa. The exotoxin (PE) of Pseudomonas aeruginosa was purified from 50-liter cultures by a simple three-step procedure, yielding 135 mg of essentially homogeneous protein. In Ouchterlony gel diffusion, PE produces a single line which doe... | [
-0.1195557564496994,
-0.007174740079790354,
-0.057066235691308975,
0.014005365781486034,
-0.011045423336327076,
-0.03582592308521271,
0.06268104910850525,
0.03135359287261963,
-0.038095444440841675,
0.04798012226819992,
-0.012959299609065056,
-0.08615424484014511,
0.026342211291193962,
0.0... |
PMID:11188 | Serum bactericidal activity in the horseshoe crab, Limulus polyphemus. | Serum from the horseshoe crab, Limulus polyphemus, was examined for bactericidal activity against five species of bacteria. Greatest activity was found against Pseudomonas putida and Flavobacterium sp.; with the former, serum dilutions as high as 1:20 were capable of reducing viable counts by 50% within 2 h. Bactericid... | Serum bactericidal activity in the horseshoe crab, Limulus polyphemus. Serum from the horseshoe crab, Limulus polyphemus, was examined for bactericidal activity against five species of bacteria. Greatest activity was found against Pseudomonas putida and Flavobacterium sp.; with the former, serum dilutions as high as 1:... | [
0.00600402383133769,
-0.023746071383357048,
0.04224531725049019,
-0.027622053399682045,
0.03556413948535919,
-0.05012912675738335,
0.0733102411031723,
0.06985526531934738,
-0.06433584541082382,
-0.04245625436306,
0.04731905832886696,
-0.05704387649893761,
-0.014972002245485783,
-0.01322784... |
PMID:11189 | Immunity to Mycobacterium leprae infections in mice stimulated by M. leprae, BCG, and graft-versus-host reactions. | Infections of mice with Mycobacterium leprae in one rear foot pad immunized them against a second infection in the other rear foot pad. Purified bacilli harvested from the first infection also produced immuniy when injection into the foot pads of previously uninfected mice. Injections of BCG afforded similar protection... | Immunity to Mycobacterium leprae infections in mice stimulated by M. leprae, BCG, and graft-versus-host reactions. Infections of mice with Mycobacterium leprae in one rear foot pad immunized them against a second infection in the other rear foot pad. Purified bacilli harvested from the first infection also produced imm... | [
-0.03904447704553604,
0.04035618528723717,
-0.013899770565330982,
0.028326410800218582,
0.05961671844124794,
-0.09029971808195114,
0.051635824143886566,
0.08866765350103378,
-0.06688098609447479,
0.007031765300780535,
0.02916937693953514,
-0.06561925262212753,
0.02308604121208191,
-0.04308... |
PMID:11191 | The distribution of hepatitis B surface antigen in Africa and the tropics: report of a population study in Nigeria. | This preliminary study was designed to examine the distribution of hepatitis B surface antigen (HBsAg) in two contrasting groups in an urban area situated in the tropical forest belt. The sample from the traditional area represents a population of low socio-economic status, living in the central slum areas of the city,... | The distribution of hepatitis B surface antigen in Africa and the tropics: report of a population study in Nigeria. This preliminary study was designed to examine the distribution of hepatitis B surface antigen (HBsAg) in two contrasting groups in an urban area situated in the tropical forest belt. The sample from the ... | [
-0.0007312801317311823,
0.04394226148724556,
-0.023239947855472565,
0.0035877320915460587,
0.07124041765928268,
0.007673528045415878,
0.07793145626783371,
0.05765315890312195,
-0.029750533401966095,
0.009669650346040726,
-0.006302754394710064,
-0.132736474275589,
-0.020199541002511978,
-0.... |
PMID:11192 | Thermal fragmentation of Escherichia coli beta-galactosidase. Isolation and characterization of an alpha-complementing and two non-complementing polypeptide fractions. | Carboxymethylated Escherichia coli beta-galactosidase EC 3.2.1.23 could be broken to polypeptides of fairly uniform size (average molecular weight about 22,000 daltons) by heating for less than or equal to 8 h at 100 degrees C and pH 7.5 IN 8 M-urea. Using phosphocellulose chromatography in NaCl-urea gradients, the res... | Thermal fragmentation of Escherichia coli beta-galactosidase. Isolation and characterization of an alpha-complementing and two non-complementing polypeptide fractions. Carboxymethylated Escherichia coli beta-galactosidase EC 3.2.1.23 could be broken to polypeptides of fairly uniform size (average molecular weight about... | [
-0.11441670358181,
-0.02430441975593567,
0.00283622439019382,
-0.045572277158498764,
0.029555698856711388,
-0.0035748393274843693,
0.02779640071094036,
0.029323583468794823,
-0.025062328204512596,
0.004202475771307945,
0.04852278530597687,
-0.06637300550937653,
-0.03559892997145653,
0.0382... |
PMID:11193 | The effects of hallucinogens on blind monkeys. | Two blind monkeys were studied with an observational profile that was previously shown to distinguish the effects of hallucinogens from those of other classes of drugs. Lysergic acid diethylamide and dimethyltryptamine could be distinguished from saline, chlorpromazine, d-amphetamine sulfate, and bromo-lysergic acid di... | The effects of hallucinogens on blind monkeys. Two blind monkeys were studied with an observational profile that was previously shown to distinguish the effects of hallucinogens from those of other classes of drugs. Lysergic acid diethylamide and dimethyltryptamine could be distinguished from saline, chlorpromazine, d-... | [
-0.010979541577398777,
-0.013495340943336487,
0.026600206270813942,
0.057453665882349014,
0.022443506866693497,
0.047028861939907074,
0.09827972948551178,
0.0009432738879695535,
-0.027014946565032005,
-0.05306321382522583,
0.05885576829314232,
0.032099369913339615,
0.010615822859108448,
0.... |
PMID:11194 | A review of psychotropic medications and the glaucomas. | Four general groups of psychotropic drugs are examined with respect to possible adverse effects upon intraocular pressure. After a brief discussion of the various mechanisms of the glaucomas, both general and specific information is provided and discussed concerning antipsychotic, antidepressant, antiparkinsonian and a... | A review of psychotropic medications and the glaucomas. Four general groups of psychotropic drugs are examined with respect to possible adverse effects upon intraocular pressure. After a brief discussion of the various mechanisms of the glaucomas, both general and specific information is provided and discussed concerni... | [
0.016795657575130463,
-0.013517184183001518,
0.04794509708881378,
-0.021090803667902946,
-0.006662479601800442,
0.03685086593031883,
0.07159776985645294,
0.022068286314606667,
-0.08279039710760117,
-0.04519708827137947,
-0.04809034988284111,
-0.016109228134155273,
0.0052423980087041855,
0.... |
PMID:11197 | [Prolactin in male reproduction]. | Prolactin (PRL), a peptide hormon from the hypophysis, becomes more interesting, since it can be determined by radioimmunassays. The release of prolactin is controlled by two not yet identified factors, the prolactin-releasing-factor and the prolactin-inhibiting-factor. The latter predominantes. Many pharmacological su... | [Prolactin in male reproduction]. Prolactin (PRL), a peptide hormon from the hypophysis, becomes more interesting, since it can be determined by radioimmunassays. The release of prolactin is controlled by two not yet identified factors, the prolactin-releasing-factor and the prolactin-inhibiting-factor. The latter pred... | [
-0.00483977934345603,
0.06896600872278214,
0.019857730716466904,
-0.003421446308493614,
0.022406795993447304,
0.015288949012756348,
0.030171560123562813,
-0.008327656425535679,
-0.021237432956695557,
-0.06035793200135231,
-0.0007014939328655601,
-0.06486673653125763,
0.0052772765047848225,
... |
PMID:11198 | Rapid microspectrofluorometric studies in EL2 cells following intracellular accumulation of dibenzocarbazoles. | Microspectrofluorometric observations were carried out in EL2 ascites cancer cells and dibenzo(a,e)fluoranthene (diB(a,e)F)-grown EL2 cells, following treatment (5 min) with three dibenzocarbazoles (1,2,7,8; 1,2,5,6 and 3,4,5,6). After microinjection of glucose-6-P leading to reduction of NAD(P), a sequence of differen... | Rapid microspectrofluorometric studies in EL2 cells following intracellular accumulation of dibenzocarbazoles. Microspectrofluorometric observations were carried out in EL2 ascites cancer cells and dibenzo(a,e)fluoranthene (diB(a,e)F)-grown EL2 cells, following treatment (5 min) with three dibenzocarbazoles (1,2,7,8; 1... | [
-0.029416963458061218,
0.009740166366100311,
0.016129087656736374,
0.02545403689146042,
0.03931272402405739,
0.028714748099446297,
0.00505472719669342,
0.03458801284432411,
-0.03313693404197693,
-0.015671776607632637,
0.03674079105257988,
-0.07235684990882874,
0.003401203081011772,
-0.0069... |
PMID:11196 | Full-time course studies of bovine liver glutamate dehydrogenase. Simulation of inhibition by pyridoxal-5'-phosphate. | Inhibition of bovine liver glutamate dehydrogenase by pyridoxal-5'-phosphate was studied by measuring the full time course of the oxidation of NADPH. Progress curves were determined before and after incubation of the enzyme with PLP in the presence of saturating concentrations of alpha-ketoglutarate and ammonium ion, a... | Full-time course studies of bovine liver glutamate dehydrogenase. Simulation of inhibition by pyridoxal-5'-phosphate. Inhibition of bovine liver glutamate dehydrogenase by pyridoxal-5'-phosphate was studied by measuring the full time course of the oxidation of NADPH. Progress curves were determined before and after inc... | [
-0.046380676329135895,
0.033895719796419144,
-0.012058212421834469,
0.009128827601671219,
0.029506472870707512,
0.0014420649968087673,
0.039041969925165176,
0.016321973875164986,
-0.02142336592078209,
-0.04251878708600998,
0.05504237115383148,
-0.016805699095129967,
0.06512036174535751,
0.... |
PMID:11199 | Adenosine triphosphate hydrolysis in rat dental tissues. A histochemical study of ion dependencies. | The effect of EDTA-decalcification, reactivating and activating procedures on the hydrolysis of ATP was studied histochemically in developing dental tissues in the rat. The incubation media contained lead citrate at alkaline pH and lead nitrate at neutral pH, and the results with ATP as substrate were compared with tho... | Adenosine triphosphate hydrolysis in rat dental tissues. A histochemical study of ion dependencies. The effect of EDTA-decalcification, reactivating and activating procedures on the hydrolysis of ATP was studied histochemically in developing dental tissues in the rat. The incubation media contained lead citrate at alka... | [
-0.05459116771817207,
-0.002965348307043314,
0.05604052543640137,
-0.013840108178555965,
-0.02534623071551323,
-0.048874229192733765,
0.03802815079689026,
0.04880745708942413,
-0.020015541464090347,
-0.011126742698252201,
0.05495813861489296,
-0.0637943223118782,
-0.0500999353826046,
-0.00... |
PMID:11200 | [An improved histofluorescence procedure for freeze-dried paraffin-embedded tissue based on combined formaldehyde-glyoxylic acid perfusion with high magnesium content and acid pH]. | A technique is described for highly sensitive and precise visualization of central catecholamine systems in paraffin sections of freeze-dried tissue. The procedure is based on perfusion of the animal with a solution containing formaldehyde and/or glyoxylic acid, in the presence of a very high magnesium content (40 g Mg... | [An improved histofluorescence procedure for freeze-dried paraffin-embedded tissue based on combined formaldehyde-glyoxylic acid perfusion with high magnesium content and acid pH]. A technique is described for highly sensitive and precise visualization of central catecholamine systems in paraffin sections of freeze-dri... | [
-0.01141152624040842,
0.007740046828985214,
0.0009624919621273875,
0.0376986600458622,
0.01888687163591385,
0.021930506452918053,
0.05677776411175728,
0.033342961221933365,
-0.026334501802921295,
-0.017491508275270462,
0.012207480147480965,
-0.04376227781176567,
0.044771187007427216,
0.064... |
PMID:11201 | [Pharmacologic aspects in the management of inner ear disease (author's transl)]. | Our knowledge of the effects of drugs on the inner ear is extremely insufficient when compared to their effects on other organs. The role of drugs commonly recommended for therapy of inner ear disorders (such as, procaine, antihistaminics, diuretics, osmotics, corticoids and substances changing blood viscosity) has yet... | [Pharmacologic aspects in the management of inner ear disease (author's transl)]. Our knowledge of the effects of drugs on the inner ear is extremely insufficient when compared to their effects on other organs. The role of drugs commonly recommended for therapy of inner ear disorders (such as, procaine, antihistaminics... | [
-0.010258150286972523,
-0.05364477261900902,
0.03040379285812378,
-0.023448606953024864,
-0.057500917464494705,
0.011310487054288387,
0.05548214167356491,
0.035288531333208084,
-0.1029912531375885,
-0.057286765426397324,
0.0221319030970335,
-0.0584607757627964,
-0.016077322885394096,
0.047... |
PMID:11205 | Thin layer chromatographic identification of some sympathomimetic amines. | Thin layer chromatographic behavior of some sympathomimetic amines in the presence of acids in neutral and organic solvent systems is reported. The sympathomimetic amines were dissolved in 0.1N HCl or ethanol and treated with bromocresol green or p-nitrobenzoyl chloride reagents on fiber sheets or precoated glass plate... | Thin layer chromatographic identification of some sympathomimetic amines. Thin layer chromatographic behavior of some sympathomimetic amines in the presence of acids in neutral and organic solvent systems is reported. The sympathomimetic amines were dissolved in 0.1N HCl or ethanol and treated with bromocresol green or... | [
-0.04571587219834328,
0.02233443222939968,
-0.01998858153820038,
-0.005404273979365826,
0.011665042489767075,
0.03716021403670311,
0.04110617935657501,
0.02689039334654808,
-0.04806246981024742,
-0.03691502660512924,
-0.027503682300448418,
-0.02341204322874546,
-0.00009922989556798711,
0.0... |
PMID:11206 | Evidence for a negative membrane potential and for movement of C1- against its electrochemical gradient in the ascomycete Neocosmospora vasinfecta. | The iodides of three lipid-soluble cations (dibenzyldimethylammonium; tribenzylmethylammonium, TBMA+; ethyldimethylbenzylammonium) were synthesized by the reaction of 14C-labeled methyl or 14C-labeled ethyl iodide with the appropriate secondary of tertiary amine and used in an attempt to measure the transmembrane elect... | Evidence for a negative membrane potential and for movement of C1- against its electrochemical gradient in the ascomycete Neocosmospora vasinfecta. The iodides of three lipid-soluble cations (dibenzyldimethylammonium; tribenzylmethylammonium, TBMA+; ethyldimethylbenzylammonium) were synthesized by the reaction of 14C-l... | [
-0.07360214740037918,
-0.03479168564081192,
-0.008414795622229576,
0.005500867031514645,
0.04418594017624855,
-0.02439476177096367,
0.056927308440208435,
0.02806159108877182,
-0.04744953662157059,
0.02777160331606865,
0.04366453364491463,
-0.07647830247879028,
0.015451332554221153,
-0.0332... |
PMID:11207 | Unique aspects of the regulation of the aspartate transcarbamylase of Serratia marcescens. | Aspartate trancarbamylase (ATC ase; EC 2.1.3.2) from Serratia marcescens HY has been purified 134-fold. Its properties are unique. Unlike the ATCase from Escherichia coli and Salmonella typhimurium, the S. marcescens HY enzyme activity is not feedback inhibited by any purine or pyrimidine nucleotide effectors; instead,... | Unique aspects of the regulation of the aspartate transcarbamylase of Serratia marcescens. Aspartate trancarbamylase (ATC ase; EC 2.1.3.2) from Serratia marcescens HY has been purified 134-fold. Its properties are unique. Unlike the ATCase from Escherichia coli and Salmonella typhimurium, the S. marcescens HY enzyme ac... | [
-0.10627984255552292,
0.031427644193172455,
-0.011714593507349491,
0.07829317450523376,
0.002598816528916359,
-0.06752662360668182,
0.0787866860628128,
0.03564285486936569,
-0.05062595009803772,
-0.0063695767894387245,
0.059273846447467804,
-0.04427473619580269,
0.0017362114740535617,
0.02... |
PMID:11208 | Reduced nicotinamide adenine dinucleotide oxidase activity in membranes and cytoplasm of Acholeplasma laidlawii and Mycoplasma mycoides subsp. capri. | The properties of the membrane-bound reduced nicotinamide adenine dinucleotide (NADH) oxidase of Acholeplasma laidlawii were compared with those of the corresponding cytoplasmic activity of Mycoplasma mycoides subsp. capri. The striking differences in pH optima, susceptibility to inhibitors and detergents, and heat ina... | Reduced nicotinamide adenine dinucleotide oxidase activity in membranes and cytoplasm of Acholeplasma laidlawii and Mycoplasma mycoides subsp. capri. The properties of the membrane-bound reduced nicotinamide adenine dinucleotide (NADH) oxidase of Acholeplasma laidlawii were compared with those of the corresponding cyto... | [
-0.050289180129766464,
-0.02568226121366024,
-0.0407862514257431,
0.0210743211209774,
0.04891170561313629,
-0.07531369477510452,
0.06026899814605713,
0.010801049880683422,
-0.0017601895378902555,
-0.03358880430459976,
-0.0015744639094918966,
-0.07945121079683304,
0.041516177356243134,
-0.0... |
PMID:11210 | Calcium transport ATPase of canine cardiac sarcoplasmic reticulum. A comparison with that of rabbit fast skeletal muscle sarcoplasmic reticulum. | To define the mechanism responsible for the slow rate of calcium transport by cardiac sarcoplasmic reticulum, the kinetic properties of the Ca2+-dependent ATPase of canine cardiac microsomes were characterized and compared with those of a comparable preparation from rabbit fast skeletal muscle. A phosphoprotein interme... | Calcium transport ATPase of canine cardiac sarcoplasmic reticulum. A comparison with that of rabbit fast skeletal muscle sarcoplasmic reticulum. To define the mechanism responsible for the slow rate of calcium transport by cardiac sarcoplasmic reticulum, the kinetic properties of the Ca2+-dependent ATPase of canine car... | [
-0.07497821003198624,
-0.03764226287603378,
-0.020290281623601913,
0.002227397868409753,
-0.019306665286421776,
-0.01949710212647915,
-0.01719120889902115,
0.02439902350306511,
0.03175109997391701,
0.007415775675326586,
0.02315741963684559,
-0.1257796287536621,
-0.0076497700065374374,
0.02... |
PMID:11211 | Purification and characterization of L-asparaginase with anti-lymphoma activity from Vibrio succinogenes. | Homogeneols L-asparaginase with anti-lymphoma activity was prepared from Vibrio succinogenes, an anaerobic bacterium from the bovine rumen. An overall yield of pure L-asparaginase of 40 to 45% and a specific activity of 200 +/- 2 IU per mg of protein was obtained. The pure enzyme can be stored at -20 degrees for at lea... | Purification and characterization of L-asparaginase with anti-lymphoma activity from Vibrio succinogenes. Homogeneols L-asparaginase with anti-lymphoma activity was prepared from Vibrio succinogenes, an anaerobic bacterium from the bovine rumen. An overall yield of pure L-asparaginase of 40 to 45% and a specific activi... | [
-0.03130604326725006,
-0.0032259311992675066,
-0.04103974252939224,
0.04484633728861809,
-0.0027764015831053257,
-0.05536994710564613,
0.03627317398786545,
0.09158942848443985,
-0.03695935755968094,
0.014480653218925,
0.03176604211330414,
-0.05446802079677582,
0.0367375947535038,
0.0469213... |
PMID:11212 | Hydrogen ion interactions of horse spleen ferritin and apoferritin. | The interactions of horse spleen ferritin and its derivative apoferritin with H+ ions were studied by potentiometric and spectrophotometric titration; to aid in data analysis, heats of ionization over a limited pH range and amide content were also determined. Per apoferritin subunit, all tyrosine and cysteine side chai... | Hydrogen ion interactions of horse spleen ferritin and apoferritin. The interactions of horse spleen ferritin and its derivative apoferritin with H+ ions were studied by potentiometric and spectrophotometric titration; to aid in data analysis, heats of ionization over a limited pH range and amide content were also dete... | [
-0.08486168086528778,
0.008295143023133278,
-0.014425652101635933,
0.008650917559862137,
0.009167916141450405,
-0.03175405412912369,
0.08743944764137268,
0.019264845177531242,
-0.049321919679641724,
-0.004679814446717501,
0.03562774881720543,
-0.10353351384401321,
0.014372117817401886,
0.0... |
PMID:11213 | Purification and properties of two aromatic aminotransferases in Bacillus subtilis. | Two enzymes which transaminate tyrosine and phenylalanine in Bacillus subtilis were each purified over 200-fold and partially characterized. One of the enzymes, termed histidinol phosphate aminotransferase, is also active with imidazole acetyl phosphate as the amino group recipient. Previous studies have shown that mut... | Purification and properties of two aromatic aminotransferases in Bacillus subtilis. Two enzymes which transaminate tyrosine and phenylalanine in Bacillus subtilis were each purified over 200-fold and partially characterized. One of the enzymes, termed histidinol phosphate aminotransferase, is also active with imidazole... | [
-0.04830152168869972,
0.009749915450811386,
-0.05264079570770264,
-0.027542822062969208,
-0.029049618169665337,
-0.022628409788012505,
0.056686896830797195,
0.00030637410236522555,
-0.06361077725887299,
-0.026908043771982193,
0.024313457310199738,
-0.11573555320501328,
0.06976644694805145,
... |
PMID:11214 | A new oxygenase, 2-nitropropane dioxygenase of Hansenula mrakii. Enzymologic and spectrophotometric properties. | 2-Nitropropane dioxygenase, purified to homogeneity from Hansenula mrakii (IFO 0895), has a molecular weight of approximately 62,000 and consists of two subunits nonidentical in molecular weight (39,000 and 25,000). Stoichiometrical studies and the results obtained with 18O2 showed that 2 atoms of molecular oxygen are ... | A new oxygenase, 2-nitropropane dioxygenase of Hansenula mrakii. Enzymologic and spectrophotometric properties. 2-Nitropropane dioxygenase, purified to homogeneity from Hansenula mrakii (IFO 0895), has a molecular weight of approximately 62,000 and consists of two subunits nonidentical in molecular weight (39,000 and 2... | [
-0.09686949849128723,
0.034596629440784454,
-0.04029153659939766,
0.01709054782986641,
0.03666160628199577,
-0.034584932029247284,
0.0301827359944582,
0.0672837570309639,
-0.07856930792331696,
-0.023627987131476402,
0.028329623863101006,
-0.06346018612384796,
0.0333188958466053,
0.02633311... |
PMID:11215 | Reconstitution of biological molecular generators of electric current. H+-ATPase. | 1. Generation of a transmembrane electric potential difference by oligomycin-sensitive ATPase complex, incorporated into spherical or planar phospholipid membrane, has been demonstrated. To this end, penetrating anion probe and direct voltmeter measurement of electric potential across phospholipid membrane were used. I... | Reconstitution of biological molecular generators of electric current. H+-ATPase. 1. Generation of a transmembrane electric potential difference by oligomycin-sensitive ATPase complex, incorporated into spherical or planar phospholipid membrane, has been demonstrated. To this end, penetrating anion probe and direct vol... | [
-0.06308276951313019,
0.007510927971452475,
-0.024111386388540268,
0.022323770448565483,
-0.042332153767347336,
-0.06966399401426315,
0.033973973244428635,
0.037953805178403854,
-0.00706052128225565,
-0.011915246024727821,
0.011999365873634815,
-0.05924654379487038,
-0.006333834491670132,
... |
PMID:11216 | Mechanism of intramolecular activation of pepsinogen. Evidence for an intermediate delta and the involvement of the active site of pepsin in the intramolecular activation of pepsinogen. | Intramolecular pepsinogen activation is inhibited either by pepstatin, a potent pepsin inhibitor, or by purified globin from hemoglobin, a good pepsin substrate. Also, pepsinogen at pH 2 can be bound to a pepstatin-Sepharose column and recovered as native zymogen upon elution in pH 8 buffer. Kinetic studies of the glob... | Mechanism of intramolecular activation of pepsinogen. Evidence for an intermediate delta and the involvement of the active site of pepsin in the intramolecular activation of pepsinogen. Intramolecular pepsinogen activation is inhibited either by pepstatin, a potent pepsin inhibitor, or by purified globin from hemoglobi... | [
-0.051082711666822433,
-0.02627450041472912,
-0.04884316399693489,
0.007973331026732922,
0.005232398863881826,
-0.025661109015345573,
0.10621190816164017,
0.02198811247944832,
-0.02657613530755043,
-0.017353974282741547,
0.012505252845585346,
-0.062277790158987045,
0.006341502536088228,
0.... |
PMID:11217 | Temperature dependence of cholesterol binding to cytochrome P-450scc of the rat adrenal. Effect of adrenocorticotropic hormone and cycloheximide. | A type I absorbance change is observed in suspensions of adrenal cortical mitochondria as the temperature is increased from 0-22 degrees. This "heat-generated" type I absorbance change is similar in magnitude to the pregnenolone-induced type II absorbance change of these mitochondria. Studies with inhibitors of cholest... | Temperature dependence of cholesterol binding to cytochrome P-450scc of the rat adrenal. Effect of adrenocorticotropic hormone and cycloheximide. A type I absorbance change is observed in suspensions of adrenal cortical mitochondria as the temperature is increased from 0-22 degrees. This "heat-generated" type I absorba... | [
-0.04299470782279968,
0.028040926903486252,
-0.014056703075766563,
0.03575257211923599,
0.05198449641466141,
-0.0021990560926496983,
0.043648622930049896,
-0.0259254053235054,
-0.015928680077195168,
-0.05536413565278053,
-0.003982183523476124,
-0.03637741133570671,
0.00911787897348404,
0.0... |
PMID:11218 | 6-Phosphogluconate dehydrogenase. Purification and kinetics. | A method is described for the isolation and purification of 6-phosphogluconate dehydrogenase from pig liver. The molecular weight is estimated at 83,000 and that of the subunits is 42,000 as determined by gel electrophoresis. The pH maximum is 8.5 in 50 mM glycine/NaOH buffer and from 7.5 to 10 in 50 mM phosphate buffe... | 6-Phosphogluconate dehydrogenase. Purification and kinetics. A method is described for the isolation and purification of 6-phosphogluconate dehydrogenase from pig liver. The molecular weight is estimated at 83,000 and that of the subunits is 42,000 as determined by gel electrophoresis. The pH maximum is 8.5 in 50 mM gl... | [
-0.02743624337017536,
0.028951086103916168,
-0.02148338034749031,
-0.015068365260958672,
-0.033870358020067215,
-0.03343719244003296,
0.0287152286618948,
0.019448010250926018,
-0.04940202459692955,
0.018437866121530533,
0.05306122079491615,
-0.0706419050693512,
-0.0248581450432539,
0.00645... |
PMID:11219 | Energy-dependent calcium transport in endoplasmic reticulum of adipocytes. | The endoplasmic reticulum from isolated rat adipocytes has the ability to actively accumulate calcium. The calcium uptake was characterized using the 20,000 X g supernatant (S1 fraction) of total cellular homogenate. Endoplasmic reticulum vesicles isolated from the S1 fraction as a 160,000 X g microsomal pellet prior t... | Energy-dependent calcium transport in endoplasmic reticulum of adipocytes. The endoplasmic reticulum from isolated rat adipocytes has the ability to actively accumulate calcium. The calcium uptake was characterized using the 20,000 X g supernatant (S1 fraction) of total cellular homogenate. Endoplasmic reticulum vesicl... | [
-0.04463023319840431,
-0.05086831375956535,
-0.01288268156349659,
-0.0013335651019588113,
-0.006395772099494934,
0.0011660477612167597,
0.04352211207151413,
-0.008371483534574509,
-0.004690725356340408,
0.010760962031781673,
0.06735814362764359,
-0.12370453029870987,
0.021448519080877304,
... |
PMID:11221 | A quantitative description of the extension and retraction of surface protrusions in spreading 3T3 mouse fibroblasts. | We suggest a method of quantitating the motile actions of surface protrusions in spreading animal cells in culture. Its basis is the determination of the percentage of freshly plated cells which produce particle-free areas around them on a gold particle-coated glass cover slip within 50 min. Studying 3T3 cells with thi... | A quantitative description of the extension and retraction of surface protrusions in spreading 3T3 mouse fibroblasts. We suggest a method of quantitating the motile actions of surface protrusions in spreading animal cells in culture. Its basis is the determination of the percentage of freshly plated cells which produce... | [
-0.05914771556854248,
-0.03216613829135895,
0.03313055261969566,
0.059847548604011536,
0.008485348895192146,
-0.004824221599847078,
0.03539063408970833,
0.01774987392127514,
-0.03447047621011734,
0.036204010248184204,
0.061302945017814636,
-0.09729033708572388,
-0.006018424406647682,
0.008... |
PMID:11220 | Long-term results of mammary artery implants. | Eighty out of eighty-six patients (93%) with mammary artery implants were followed postoperatively for an average of three and a half years. The immediate mortality rate was 7% (6 cases), and the late mortality was 6% (5 cases). All had angina preoperatively. Twenty-four had a history of myocardial infarction and thirt... | Long-term results of mammary artery implants. Eighty out of eighty-six patients (93%) with mammary artery implants were followed postoperatively for an average of three and a half years. The immediate mortality rate was 7% (6 cases), and the late mortality was 6% (5 cases). All had angina preoperatively. Twenty-four ha... | [
-0.0009142690105363727,
0.011364515870809555,
0.02445073425769806,
0.06285040080547333,
-0.01524015236645937,
-0.0359969288110733,
0.01239338144659996,
0.05819002166390419,
-0.0077021438628435135,
-0.033057209104299545,
-0.016633816063404083,
-0.04843318834900856,
0.002095787087455392,
-0.... |
PMID:11222 | Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium. | The brush border of intestinal epithelial cells consists of an array of tightly packed microvilli. Within each microvillus is a bundle of 20-30 actin filaments. The basal ends of the filament bundles are embedded in and interconected by a filamentous meshwork, the terminal web, which lies directly beneath the microvill... | Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium. The brush border of intestinal epithelial cells consists of an array of tightly packed microvilli. Within each microvillus is a bundle of 20-30 actin filaments. The basal ends of the filament bundles are ... | [
-0.0626649335026741,
-0.07851677387952805,
0.0406293049454689,
0.06213320791721344,
-0.0045126378536224365,
-0.04741253703832626,
0.033923689275979996,
0.02501429058611393,
0.026250217109918594,
0.017102854326367378,
0.02759184129536152,
-0.11038520187139511,
-0.04733072221279144,
0.012126... |
PMID:11223 | pH-dependent binding of immunoglobulins to intestinal cells of the neonatal rat. | Rat and rabbit IgG immunoglobulins conjugated to horseradiah peroxidase as a histochemical marker bind at 0 degrees C to the luminal surface of absorptive cells in isolated segments of jejunum from 10-12-day old rats. Binding is observed at pH 6.0, near the normal luminal pH of the duodenum and jejunum at this age, but... | pH-dependent binding of immunoglobulins to intestinal cells of the neonatal rat. Rat and rabbit IgG immunoglobulins conjugated to horseradiah peroxidase as a histochemical marker bind at 0 degrees C to the luminal surface of absorptive cells in isolated segments of jejunum from 10-12-day old rats. Binding is observed a... | [
-0.08086910843849182,
-0.020567715167999268,
-0.01926194503903389,
-0.006256545428186655,
-0.00037952567799948156,
-0.047021862119436264,
0.11435665935277939,
0.05824075639247894,
-0.06727635115385056,
-0.00015363041893579066,
-0.014101993292570114,
-0.049233026802539825,
0.01040974538773298... |
PMID:11224 | Dietary phosphate deprivation in women and men: effects on mineral and acid balances, parathyroid hormone and the metabolism of 25-OH-vitamin D. | We evaluated the effects of dietary PO4 restriction on 25-OH-Vitamin D3 metabolism, serum iPTH levels, and mineral balances in healthy women and men. PO4 balances were progressively negative because of fecal losses without sex difference. Turnover of the plasma 25-OH-D pool was increased from 5.8 +/- 0.4 to 12 +/- 1.2 ... | Dietary phosphate deprivation in women and men: effects on mineral and acid balances, parathyroid hormone and the metabolism of 25-OH-vitamin D. We evaluated the effects of dietary PO4 restriction on 25-OH-Vitamin D3 metabolism, serum iPTH levels, and mineral balances in healthy women and men. PO4 balances were progres... | [
0.010638101026415825,
0.021258704364299774,
0.011163328774273396,
0.026107383891940117,
0.02642015367746353,
-0.02904394268989563,
0.02992212027311325,
0.05242398381233215,
-0.038784123957157135,
0.002410690765827894,
0.04966932535171509,
-0.1287325918674469,
0.06995538622140884,
-0.015900... |
PMID:11225 | Size heterogeneity of human serum somatomedin. | Somatomedin (SM) in unextracted human serum was studied by Sephadex chromatography, starch gel electrophoresis, and in vitro SM bioassays. Repeated rechromatography of the various serum fractions revealed SM activity in a variety of indicated molecular size (IMS) areas; greater than 90,000, (very large); 90,000-20,000,... | Size heterogeneity of human serum somatomedin. Somatomedin (SM) in unextracted human serum was studied by Sephadex chromatography, starch gel electrophoresis, and in vitro SM bioassays. Repeated rechromatography of the various serum fractions revealed SM activity in a variety of indicated molecular size (IMS) areas; gr... | [
-0.07827457040548325,
-0.025098539888858795,
-0.003427887801080942,
-0.039114631712436676,
0.037697043269872665,
-0.022270647808909416,
0.024115627631545067,
0.028197182342410088,
-0.028081703931093216,
0.010953602381050587,
0.05379365012049675,
-0.08430859446525574,
0.021531565114855766,
... |
PMID:11226 | Evaluation of enrichment, storage, and age of blood agar medium in relation to its ability to support growth of anaerobic bacteria. | By measuring the colony size of a variety of anaerobic bacteria isolated from clinical specimens, an evaluation was made of the benefits derived from the addition of several enrichments to blood agar medium commonly used for the growth of anaerobes. Similar methods were used to study the effects of various storage cond... | Evaluation of enrichment, storage, and age of blood agar medium in relation to its ability to support growth of anaerobic bacteria. By measuring the colony size of a variety of anaerobic bacteria isolated from clinical specimens, an evaluation was made of the benefits derived from the addition of several enrichments to... | [
-0.011152989231050014,
0.03112894855439663,
-0.01307492982596159,
0.010301735252141953,
0.041617944836616516,
0.0009208026458509266,
-0.03047691099345684,
0.03552502766251564,
-0.03829352185130119,
-0.031118102371692657,
0.03240456432104111,
-0.07915299385786057,
-0.01798066310584545,
0.07... |
PMID:11227 | Mycobactericidal activity of glutaraldehyde solutions. | Aqueous solutions of alkaline glutaraldehyde (buffered at pH 8.5) inactivated a standard suspension of Mycobacterium tuberculosis H37Rv faster than the corresponding acid (pH 3.7 preparation. Quantitative differences in the rate of inactivation of eight other species of Mycobacterium were determined using a 1% solution... | Mycobactericidal activity of glutaraldehyde solutions. Aqueous solutions of alkaline glutaraldehyde (buffered at pH 8.5) inactivated a standard suspension of Mycobacterium tuberculosis H37Rv faster than the corresponding acid (pH 3.7 preparation. Quantitative differences in the rate of inactivation of eight other speci... | [
-0.012694154866039753,
-0.009806509129703045,
0.015576882287859917,
0.006281225010752678,
0.02168603241443634,
-0.10418401658535004,
0.03437168523669243,
0.01125296764075756,
-0.01558761578053236,
0.04903458058834076,
0.012299641035497189,
-0.05227680876851082,
0.061382196843624115,
-0.031... |
PMID:11233 | Coordination of classroom and clinical experience. | Clinical experience, providing opportunity to apply concepts and theories presented in the classroom, is essential in the education of a dietetic practitioner--whether it be as assistant, technician, or professional. Coordination of theory and practice is needed to permit students to acquire the knowledge, attitudes, a... | Coordination of classroom and clinical experience. Clinical experience, providing opportunity to apply concepts and theories presented in the classroom, is essential in the education of a dietetic practitioner--whether it be as assistant, technician, or professional. Coordination of theory and practice is needed to per... | [
0.03210138902068138,
0.0030855112709105015,
0.047182753682136536,
-0.010624303482472897,
-0.057251423597335815,
0.013324703089892864,
0.0532846562564373,
0.06684652715921402,
-0.00484393211081624,
-0.04038938507437706,
0.00975846592336893,
-0.022702103480696678,
-0.010198336094617844,
0.04... |
PMID:11260 | Interaction of erythrocytes with human serum proteins. I. Analysis of the effect of pH and ionic strength of the medium. | The effect of ionic parameters of the medium (pH and ionic strength) on the processes of interaction of tannin-treated erythrocytes and the protein fractions of human serum (macroglobulins, microbulins and albumin) was studied in factorial experiments. Complex effect of these parametres on the processes under investiga... | Interaction of erythrocytes with human serum proteins. I. Analysis of the effect of pH and ionic strength of the medium. The effect of ionic parameters of the medium (pH and ionic strength) on the processes of interaction of tannin-treated erythrocytes and the protein fractions of human serum (macroglobulins, microbuli... | [
-0.07319417595863342,
0.05610156059265137,
-0.033711571246385574,
0.033795066177845,
0.02742040902376175,
-0.04590923339128494,
0.12961065769195557,
0.010754400864243507,
-0.04756446182727814,
0.02066667191684246,
-0.01879756525158882,
-0.062194447964429855,
-0.0017993398942053318,
0.06919... |
PMID:11261 | Tuberculin-sensitized lymphocytes detected by altered electrophorectic mobility distributions after incubation with the antigen PPD. | Lymphocytes from donors who had had tuberculosis (a disease known to provoke a cell-mediated immunity) were incubated with the tuberculin antigen, purified protein derivative (PPD), and their distribution of electrophoretic mobility was determined by laser Doppler spectroscopy. In 75% of the cases, the distribution sho... | Tuberculin-sensitized lymphocytes detected by altered electrophorectic mobility distributions after incubation with the antigen PPD. Lymphocytes from donors who had had tuberculosis (a disease known to provoke a cell-mediated immunity) were incubated with the tuberculin antigen, purified protein derivative (PPD), and t... | [
-0.06039482727646828,
-0.03153132274746895,
-0.015515649691224098,
-0.019346987828612328,
0.010171936824917793,
-0.0010048336116597056,
0.11070578545331955,
0.023078367114067078,
-0.048269517719745636,
0.01043317373842001,
0.04504723846912384,
-0.029094185680150986,
0.020712222903966904,
-... |
PMID:11264 | Acyl specificity in triglyceride synthesis by lactating rat mammary gland. | We have studied the specificity of the acyl-CoA:diglyceride acyltransferase reaction in lactating rat mammary gland to provide a rational explanation at the enzyme level for the nonrandom distribution of fatty acids in milk fat triglycerides. Acyl-CoA:diglyceride acyltransferase activity was measured using various digl... | Acyl specificity in triglyceride synthesis by lactating rat mammary gland. We have studied the specificity of the acyl-CoA:diglyceride acyltransferase reaction in lactating rat mammary gland to provide a rational explanation at the enzyme level for the nonrandom distribution of fatty acids in milk fat triglycerides. Ac... | [
-0.018548855558037758,
-0.04124967008829117,
-0.04538128897547722,
0.0338793620467186,
0.007939479313790798,
-0.02240144833922386,
0.009417164139449596,
0.031352683901786804,
-0.06851527094841003,
-0.05536576732993126,
0.05240073800086975,
-0.09124297648668289,
0.012583708390593529,
-0.027... |
PMID:11265 | The coordinate roles of branchial nerve activity and potassium in the stimulation of ciliary activity in Mytilus edulis: observations with phenoxybenzamine, bromolysergic acid and fluorescence histochemistry. | Potassium concentrations in excess of 30 mM increase the rate of beating of lateral cilia on the gill of Mytilus edulis. Cilioexcitation produced by low frequency (5 beats/s) electrical stimulation was potentiated with potassium but blocked with bromolysergic acid (a serotonergic inhibitor). Cilioinhibition produced by... | The coordinate roles of branchial nerve activity and potassium in the stimulation of ciliary activity in Mytilus edulis: observations with phenoxybenzamine, bromolysergic acid and fluorescence histochemistry. Potassium concentrations in excess of 30 mM increase the rate of beating of lateral cilia on the gill of Mytilu... | [
-0.01700863428413868,
-0.06881635636091232,
0.03559136390686035,
0.06803357601165771,
-0.0298684723675251,
-0.04123770073056221,
0.0573810450732708,
0.02623846009373665,
-0.017743820324540138,
-0.022212665528059006,
0.019335901364684105,
-0.10578971356153488,
-0.013381286524236202,
0.03806... |
PMID:11266 | Proline inhibition of a sea anemone alarm pheromone response. | 1. L-proline, by itself or in animal tissue extracts, inhibits the response of the sea anemone Anthopleura elegantissima to the alarm phermone, anthopeurine. 2. The effect of proline is mediated by a receptor that is specific for the structure and configuration of the part of the L-proline molecule containing the carbo... | Proline inhibition of a sea anemone alarm pheromone response. 1. L-proline, by itself or in animal tissue extracts, inhibits the response of the sea anemone Anthopleura elegantissima to the alarm phermone, anthopeurine. 2. The effect of proline is mediated by a receptor that is specific for the structure and configurat... | [
-0.04684991016983986,
0.00443037087097764,
-0.0255932305008173,
0.0016918383771553636,
-0.011992547661066055,
-0.00449356297031045,
0.05788051337003708,
0.04360431805253029,
-0.043389733880758286,
-0.029198694974184036,
0.0736287534236908,
-0.019300643354654312,
0.04486922547221184,
0.0729... |
PMID:11267 | An electrolytic method for determining oxygen dissociation curves using small blood samples: the effect of temperature on trout and human blood. | 1. A detailed account is given of an electrolytic method for determining the oxygen dissociation curve of fish blood using a single sample of 50-100 mul for the whole curve. The accuracy and some of the problems arising from its uses are discussed. 2. Oxygen dissociation curves have been determined for trout blood and ... | An electrolytic method for determining oxygen dissociation curves using small blood samples: the effect of temperature on trout and human blood. 1. A detailed account is given of an electrolytic method for determining the oxygen dissociation curve of fish blood using a single sample of 50-100 mul for the whole curve. T... | [
-0.061709385365247726,
0.06062909588217735,
0.022686900570988655,
0.015502973459661007,
0.034346699714660645,
-0.006971966940909624,
0.06503573805093765,
0.03848356753587723,
-0.05662745609879494,
-0.009415539912879467,
0.03760342672467232,
-0.11883582919836044,
-0.029203852638602257,
0.03... |
PMID:11268 | Physiology of an ATP receptor in labellar sensilla of the tsetse fly Glossina morsitans morsitans Westw. (Diptera: Glossinidae). | Electrophysiological recordings have been made from cells in the eight large, labellar sensilla of g. morsitans. One of these cells in each sensillum was shown to respond to ATP over a concentration range of 10(-6)-10(-3) M. It was also sensitive to several other adenosine phophates, but much less sensitive to CTP, GTP... | Physiology of an ATP receptor in labellar sensilla of the tsetse fly Glossina morsitans morsitans Westw. (Diptera: Glossinidae). Electrophysiological recordings have been made from cells in the eight large, labellar sensilla of g. morsitans. One of these cells in each sensillum was shown to respond to ATP over a concen... | [
0.01761791855096817,
-0.02633082866668701,
0.021892687305808067,
0.02008230611681938,
-0.020970426499843597,
-0.056400757282972336,
0.11046601831912994,
0.08584253489971161,
-0.04011429846286774,
-0.04709448292851448,
0.015506893396377563,
-0.07946813106536865,
-0.024733133614063263,
0.024... |
PMID:11269 | Nervous control of light responses in the sea anemone, Calamactis praelongus. | 1. The burrowing sea anemone, Calamactis praelongus, responds to light with local, non-nervous contractions of the column. There are also more extensive responses of the column and retractor muscles co-ordinated by nerve net pulses (NNP's) under pacemaker control. 2. NNP's occur in at least two types of bursts and in s... | Nervous control of light responses in the sea anemone, Calamactis praelongus. 1. The burrowing sea anemone, Calamactis praelongus, responds to light with local, non-nervous contractions of the column. There are also more extensive responses of the column and retractor muscles co-ordinated by nerve net pulses (NNP's) un... | [
-0.02145342156291008,
-0.0266770888119936,
0.012098042294383049,
0.03318440169095993,
0.03086988255381584,
-0.0015144256176427007,
0.06596385687589645,
0.022212861105799675,
-0.01812686398625374,
0.02261102944612503,
0.024424433708190918,
-0.018110152333974838,
-0.030512874945998192,
0.044... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.