id stringlengths 7 10 | title stringlengths 8 354 | content stringlengths 91 4.1k | contents stringlengths 164 4.24k | embedding listlengths 384 384 |
|---|---|---|---|---|
PMID:14478 | Myocardial noradrenaline uptake after coronary occlusion in the rat. | Coronary ligation produced a marked increase in labelled noradrenaline uptake by the myocardial tissue of rats. The peri-ischemic zones showed an elevated accumulation of noradrenaline on the 4th day but the intact zone had returned to normal values. At the 14th day of observation, both the ischemic and per-ischemic ti... | Myocardial noradrenaline uptake after coronary occlusion in the rat. Coronary ligation produced a marked increase in labelled noradrenaline uptake by the myocardial tissue of rats. The peri-ischemic zones showed an elevated accumulation of noradrenaline on the 4th day but the intact zone had returned to normal values. ... | [
-0.02040190063416958,
-0.04380416125059128,
-0.018864918500185013,
0.05494358390569687,
0.042624253779649734,
-0.04095354303717613,
0.11062401533126831,
-0.0041892435401678085,
-0.019162729382514954,
-0.030506689101457596,
0.01610785536468029,
-0.07513116300106049,
-0.005449932999908924,
0... |
PMID:14481 | Effects of carbachol and calcium on the cyclic guanosine-3',5'-monophosphate (cyclic GMP) metabolism in intestinal smooth muscle. | In a submaximal concentration carbachol contracted the rabbit colon muscle and increased the cyclic GMP level. The cyclic AMP level was reduced. In a Ca++-depleted muscle carbachol reduced the cyclic GMP level while the effect on the cyclic AMP content of the muscle was unchanged. Carbachol had no effect on the guanyla... | Effects of carbachol and calcium on the cyclic guanosine-3',5'-monophosphate (cyclic GMP) metabolism in intestinal smooth muscle. In a submaximal concentration carbachol contracted the rabbit colon muscle and increased the cyclic GMP level. The cyclic AMP level was reduced. In a Ca++-depleted muscle carbachol reduced t... | [
-0.04133622348308563,
-0.0527675487101078,
0.031786516308784485,
-0.01182403415441513,
-0.014147884212434292,
-0.042044203728437424,
-0.01625644601881504,
0.025638749822974205,
-0.02860189601778984,
-0.0455368310213089,
0.04738251492381096,
-0.0828058198094368,
0.010319529101252556,
0.0333... |
PMID:14483 | The analysis of organic water pollutants by gas chromatography and gas chromatography-mass spectrometry. | Four methods for the analysis of trace levels or organic compounds in water have been discussed: direct aqueous injection, vapor stripping, solvent extraction, and lipophilic adsorption. Table 6 presents a comparison of these techniques. Direct injection is applicable to compounds having a wide range of polarities and ... | The analysis of organic water pollutants by gas chromatography and gas chromatography-mass spectrometry. Four methods for the analysis of trace levels or organic compounds in water have been discussed: direct aqueous injection, vapor stripping, solvent extraction, and lipophilic adsorption. Table 6 presents a compariso... | [
-0.006704016588628292,
0.0239563025534153,
0.012198004871606827,
-0.06600861996412277,
0.04556817561388016,
-0.04363621771335602,
0.0041819047182798386,
-0.0047904131934046745,
-0.04507578909397125,
-0.06754317134618759,
-0.0036313047166913748,
-0.036809321492910385,
-0.01172509603202343,
... |
PMID:14482 | [Comparison of the effects of oxazepam and oxypertine in treatment of anxious depressive neuroses]. | The author has treated with the double blind method 38 neurotic patients, hysterical or obsessionnal type, in a state of anxious depressive relapse. Some patients received oxazepam (3 X 15 mg per day), others received oxypertine (3X 10 mg per day); this chemotherapy was completed with supportive psychotherapy. Patients... | [Comparison of the effects of oxazepam and oxypertine in treatment of anxious depressive neuroses]. The author has treated with the double blind method 38 neurotic patients, hysterical or obsessionnal type, in a state of anxious depressive relapse. Some patients received oxazepam (3 X 15 mg per day), others received ox... | [
-0.035387083888053894,
0.022428415715694427,
0.022306526079773903,
0.031362298876047134,
0.0021144140046089888,
0.03830931335687637,
0.024007301777601242,
-0.032877225428819656,
0.0026603364385664463,
-0.11633940786123276,
-0.03793623670935631,
-0.014507238753139973,
0.03748948127031326,
0... |
PMID:14485 | Renin and age as determinants of a predominantly betablocker-based antihypertensive drug program. | Patients with essential hypertension can be subdivided into groups with low (19%), normal (59%) or high (23%) renin sodium index. The proportion with low renin hypertension increases with age. Patients with high renin fall in two categories: younger patients with fairly mild hypertension and older patients with more se... | Renin and age as determinants of a predominantly betablocker-based antihypertensive drug program. Patients with essential hypertension can be subdivided into groups with low (19%), normal (59%) or high (23%) renin sodium index. The proportion with low renin hypertension increases with age. Patients with high renin fall... | [
-0.052451182156801224,
0.023809993639588356,
-0.014384954236447811,
0.01600528135895729,
-0.007467650342732668,
-0.02325212024152279,
0.039238885045051575,
0.014279193244874477,
-0.016828255727887154,
-0.04544929042458534,
0.006668654270470142,
0.004974203184247017,
0.01522776484489441,
0.... |
PMID:14490 | The importance of bites by the saw-scaled or carpet viper (Echis carinatus): epidemiological studies in Nigeria and a review of the world literature. | The incidence of Echis carinatus (saw-scaled or carpet viper) bite and its mortality have been investigated in the Nigerian savanna region. A geographical area was defined in which the snake was particularly abundant and bites were frequent. Perennial and seasonal fluctuations in incidence and mortality, the circumstan... | The importance of bites by the saw-scaled or carpet viper (Echis carinatus): epidemiological studies in Nigeria and a review of the world literature. The incidence of Echis carinatus (saw-scaled or carpet viper) bite and its mortality have been investigated in the Nigerian savanna region. A geographical area was define... | [
-0.002205792348831892,
-0.020185429602861404,
0.05153154954314232,
0.0571989081799984,
0.03046380914747715,
-0.04082794860005379,
0.0994134172797203,
0.0893922969698906,
-0.042166098952293396,
0.03245377540588379,
0.033511459827423096,
-0.07018207013607025,
-0.008122720755636692,
0.0479971... |
PMID:14491 | Etiological determinants of protein calorie undernutrition in a rural child community. | Two groups of randomly selected underweight and well-nourished preschool children residing in study villages of Punjab, Ludhiana district were examined with respect to their socioeconomic background, birth weights, dietary intakes, quality of received mother care, blood biochemistry, parasite load, psychomotor developm... | Etiological determinants of protein calorie undernutrition in a rural child community. Two groups of randomly selected underweight and well-nourished preschool children residing in study villages of Punjab, Ludhiana district were examined with respect to their socioeconomic background, birth weights, dietary intakes, q... | [
0.012057924643158913,
-0.004116526804864407,
0.004109994508326054,
0.02944757044315338,
0.05316305160522461,
-0.04218301549553871,
0.07241222262382507,
0.052097588777542114,
-0.04800532013177872,
-0.02239575795829296,
0.07264670729637146,
-0.08796296268701553,
0.04456048831343651,
0.007394... |
PMID:14492 | Salivary Secretion in wild Glossina pallidipes Austen. (Diptera, Glossinidae). | The salivation behaviour of wild G. pallidipes obtained from Lambwe Valley and Kbwezi was studied. Salivation was measured by counting the number of salivary drops secreted per minute and measuring the sizes of the stained saliva after drawing them with a camera lucida. The results confirmed observations obtained from ... | Salivary Secretion in wild Glossina pallidipes Austen. (Diptera, Glossinidae). The salivation behaviour of wild G. pallidipes obtained from Lambwe Valley and Kbwezi was studied. Salivation was measured by counting the number of salivary drops secreted per minute and measuring the sizes of the stained saliva after drawi... | [
0.04274449124932289,
-0.009946370497345924,
0.040345896035432816,
-0.012521651573479176,
0.005324847064912319,
-0.03504925221204758,
0.1565598100423813,
0.0671902522444725,
-0.010520712472498417,
-0.023384595289826393,
-0.0737692266702652,
-0.07566796243190765,
0.015254688449203968,
0.0272... |
PMID:14494 | Nuclear coat and viruslike particles in the midgut epithelium of Glossina morsitans sspp. | The ultrastructural aspects of the nuclear coat formation in midgut epithelial cells of pupae and adult flies of G. morsitans sspp. are described. Out of four different species of Glossina examined, this peculiar structure was only found in G. morsitans sspp. Three different types of viruslike particles were found in m... | Nuclear coat and viruslike particles in the midgut epithelium of Glossina morsitans sspp. The ultrastructural aspects of the nuclear coat formation in midgut epithelial cells of pupae and adult flies of G. morsitans sspp. are described. Out of four different species of Glossina examined, this peculiar structure was onl... | [
0.02499624714255333,
-0.0616949237883091,
0.01876198872923851,
-0.02810509316623211,
0.036051973700523376,
-0.016850456595420837,
0.09983092546463013,
0.06658747047185898,
-0.04195333644747734,
-0.014124696142971516,
-0.009787152521312237,
-0.10801278799772263,
0.017374999821186066,
-0.026... |
PMID:14496 | Comparative study of the postoperative flow in the saphenous vein and internal mammary artery bypass grafts. | Postoperative coronary bypass flow was evaluated in two groups of randomly selected patients with grafts to the left anterior descending artery (LAD). Saphenous vein bypass grafts were placed in 27 patients and internal mammary artery grafts in 25 patients. Postoperative flow studies were performed in both groups with ... | Comparative study of the postoperative flow in the saphenous vein and internal mammary artery bypass grafts. Postoperative coronary bypass flow was evaluated in two groups of randomly selected patients with grafts to the left anterior descending artery (LAD). Saphenous vein bypass grafts were placed in 27 patients and ... | [
0.026863237842917442,
-0.022112835198640823,
-0.009346087463200092,
0.029285237193107605,
-0.018119145184755325,
-0.01879521645605564,
0.03700500354170799,
0.11334946006536484,
0.03156288340687752,
0.012798215262591839,
-0.0382566824555397,
-0.0890294536948204,
-0.03686729073524475,
-0.022... |
PMID:14498 | The essential action of propranolol in hypertension. | The unique action of propranolol and other beta blockers in lowering raised arterial pressure is discussed. Although the onset of the antihypertensive effect is not immediate, many trials have confirmed the efficacy of these drugs. Animal experiments have thrown little light on the mechanism of action of beta blockers ... | The essential action of propranolol in hypertension. The unique action of propranolol and other beta blockers in lowering raised arterial pressure is discussed. Although the onset of the antihypertensive effect is not immediate, many trials have confirmed the efficacy of these drugs. Animal experiments have thrown litt... | [
-0.03870900720357895,
-0.0011627632193267345,
0.012289534322917461,
0.009773042052984238,
-0.006470569409430027,
-0.008357313461601734,
0.05035216733813286,
0.03614434599876404,
-0.011182120069861412,
-0.05840316414833069,
0.010366328060626984,
0.014610433019697666,
-0.0061242408119142056,
... |
PMID:14499 | Acute and long-term studies of the mechanisms of action of beta-blocking drugs in lowering blood pressure. | The antihypertensive effect of intravenous (acute) and oral (long-term) beta-adrenergic blockade with propranolol or pindolol was evaluated in 46 male patients with either borderline (group I; 23 patients) or sustained (group II; 23 patients) essential hypertension. Arterial pressure, plasma renin activity and plasma c... | Acute and long-term studies of the mechanisms of action of beta-blocking drugs in lowering blood pressure. The antihypertensive effect of intravenous (acute) and oral (long-term) beta-adrenergic blockade with propranolol or pindolol was evaluated in 46 male patients with either borderline (group I; 23 patients) or sust... | [
-0.053905386477708817,
0.013778536580502987,
0.003120594657957554,
0.0236525796353817,
-0.014922725036740303,
-0.03596200793981552,
0.026492448523640633,
0.003868760773912072,
-0.009701088070869446,
-0.07834579795598984,
-0.015464341267943382,
0.0019636540673673153,
0.021564412862062454,
0... |
PMID:14500 | Renin and aldosterone secretion in pheochromocytoma. Effect of chronic alpha-adrenergic receptor blockade. | Patients suffering from pheochromocytoma characterized by an exclusive or almost exclusive excess of norepinephrine showed no (one patient) or only a moderate increase (two patients) in renin and aldosterone secretion. In those three patients with concomitant distinct hypersecretion of epinephrine, renin release (and a... | Renin and aldosterone secretion in pheochromocytoma. Effect of chronic alpha-adrenergic receptor blockade. Patients suffering from pheochromocytoma characterized by an exclusive or almost exclusive excess of norepinephrine showed no (one patient) or only a moderate increase (two patients) in renin and aldosterone secre... | [
-0.03003857657313347,
-0.004963054787367582,
0.026058144867420197,
0.04856555163860321,
0.006706995889544487,
-0.021915633231401443,
0.0476173460483551,
-0.006288003642112017,
-0.0005717554013244808,
-0.05558311566710472,
-0.030277328565716743,
0.016723090782761574,
0.00007991924212547019,
... |
PMID:14501 | Experience with pindolol, a betareceptor blocker, in the treatment of hypertension. | Ten patients, mean age 48 years, with essential hypertension of stage I and II according to the WHO classification, were studied at rest and during work before and after an average of two and 16 months of oral treatment with the beta-adrenergic blocking agent, pindolol. The pindolol treatment caused a significant decre... | Experience with pindolol, a betareceptor blocker, in the treatment of hypertension. Ten patients, mean age 48 years, with essential hypertension of stage I and II according to the WHO classification, were studied at rest and during work before and after an average of two and 16 months of oral treatment with the beta-ad... | [
-0.04658237472176552,
0.014072089456021786,
0.009236270561814308,
0.018602818250656128,
-0.011473527178168297,
-0.04212714359164238,
0.026424285024404526,
0.00615957286208868,
-0.04267903044819832,
-0.05796053633093834,
0.04365892335772514,
-0.00339435413479805,
-0.015129686333239079,
0.03... |
PMID:14502 | Beta-adrenoreceptor blockade in hypertension. | There is good evidence from many sources that beta-adrenoreceptor blockade is an effective form of therapy in mild, moderate and severe hypertension either alone or in combination with other antihypertensive agents. Although a number os such beta blocking compounds are now available, they appear to have a hypotensive e... | Beta-adrenoreceptor blockade in hypertension. There is good evidence from many sources that beta-adrenoreceptor blockade is an effective form of therapy in mild, moderate and severe hypertension either alone or in combination with other antihypertensive agents. Although a number os such beta blocking compounds are now ... | [
-0.008050612173974514,
0.0063216108828783035,
0.022815383970737457,
0.041803937405347824,
-0.04369708523154259,
-0.006278479937463999,
0.035673853009939194,
0.01609523594379425,
-0.035052426159381866,
-0.07050839811563492,
0.002868285635486245,
0.006450409535318613,
-0.011687496677041054,
... |
PMID:14503 | Rapid identification of patients with essential hypertension sensitive to acebutolol (a new cardioselective beta-blocker). | Acebutolol, a new cardioselective beta-blocking agent, was administered for 48 hours to 44 patients with essential hypertension at a total dosage of 2.0 g (2,000 mg). The slowing down of their pulse rate and the decrease in blood pressure were highly significant, whereas eight subjects treated with placebos had no chan... | Rapid identification of patients with essential hypertension sensitive to acebutolol (a new cardioselective beta-blocker). Acebutolol, a new cardioselective beta-blocking agent, was administered for 48 hours to 44 patients with essential hypertension at a total dosage of 2.0 g (2,000 mg). The slowing down of their puls... | [
-0.05534156411886215,
0.039757777005434036,
-0.005334275308996439,
0.00970495119690895,
0.003927274607121944,
-0.04696274176239967,
0.0075996145606040955,
0.029655523598194122,
-0.018033679574728012,
-0.032666683197021484,
-0.013377716764807701,
0.005087025463581085,
0.01736619882285595,
0... |
PMID:14504 | Different antihypertensive effect of beta-blocking drugs in low and normal-high renin hypertension. | The treatment response to beta-adrenoceptor blocking drugs was compared in two groups of patients with primary (essential) hypertension and different renin levels. Each group consisted of 25 patients and was equally distributed regarding age, severity and stage of hypertension. In the first group (group 1), the mean up... | Different antihypertensive effect of beta-blocking drugs in low and normal-high renin hypertension. The treatment response to beta-adrenoceptor blocking drugs was compared in two groups of patients with primary (essential) hypertension and different renin levels. Each group consisted of 25 patients and was equally dist... | [
-0.06455615162849426,
0.02944714017212391,
0.000986491795629263,
0.017370453104376793,
0.004324049223214388,
-0.02936428412795067,
0.009785044938325882,
0.02606060355901718,
-0.00941995345056057,
-0.06264547258615494,
-0.01245991699397564,
0.0034947700332850218,
0.019815655425190926,
0.047... |
PMID:14505 | Gastric emptying and secretion in the rhesus monkey. | The volume and composition of the gastric contents as well as the rates of gastric emptying and secretion were determined simultaneously in conscious chair-adapted monkeys. These determinations were made during fasting and after a liquid meal, thereby allowing studies of the physiologic variables which regulate gastric... | Gastric emptying and secretion in the rhesus monkey. The volume and composition of the gastric contents as well as the rates of gastric emptying and secretion were determined simultaneously in conscious chair-adapted monkeys. These determinations were made during fasting and after a liquid meal, thereby allowing studie... | [
0.029570259153842926,
-0.005814427509903908,
0.005653491709381342,
0.027851564809679985,
0.010524571873247623,
-0.007268712855875492,
0.046923257410526276,
-0.004601569380611181,
0.02544642984867096,
-0.036842796951532364,
-0.01373404823243618,
-0.10510067641735077,
-0.009746384806931019,
... |
PMID:14506 | Impaired renal H+ secretion and NH3 production in mineralocorticoid-deficient glucocorticoid-replete dogs. | When the administration of exogenous mineralocorticoid hormones was discontinued in adrenalectomized dogs maintained on glucocorticoid, net acid excretion decreased due largely to a reduction in urinary ammonium excretion (UNH4+V), and hyperchloremic hyperkalemic metabolic acidosis occurred and persisted. The reduction... | Impaired renal H+ secretion and NH3 production in mineralocorticoid-deficient glucocorticoid-replete dogs. When the administration of exogenous mineralocorticoid hormones was discontinued in adrenalectomized dogs maintained on glucocorticoid, net acid excretion decreased due largely to a reduction in urinary ammonium e... | [
-0.022969931364059448,
-0.0349159874022007,
0.027659058570861816,
0.10483773797750473,
0.010817144066095352,
-0.04135245084762573,
0.03734232485294342,
0.03079805336892605,
-0.0509394034743309,
0.01264667697250843,
0.006766796112060547,
-0.10076482594013214,
0.054290469735860825,
0.0070962... |
PMID:14507 | Mechanism of intrarenal blood flow redistribution after carotid artery occlusion. | Bilateral carotid artery occlusion results in an increase in mean arterial pressure, an increase in renal sympathetic nerve activity, and a redistribution of renal blood flow from inner to outer cortex. To elucidate the mechanism of the renal blood flow redistribution, carotid artery occlusion was performed in anesthet... | Mechanism of intrarenal blood flow redistribution after carotid artery occlusion. Bilateral carotid artery occlusion results in an increase in mean arterial pressure, an increase in renal sympathetic nerve activity, and a redistribution of renal blood flow from inner to outer cortex. To elucidate the mechanism of the r... | [
-0.04860967770218849,
-0.026432957500219345,
-0.017910288646817207,
0.034028973430395126,
-0.014828206971287727,
-0.01703573763370514,
0.07982577383518219,
0.0259527787566185,
-0.04898194968700409,
0.019632751122117043,
-0.007923443801701069,
-0.04723392799496651,
-0.008356600068509579,
0.... |
PMID:14508 | A smooth muscle active factor isolated from renal cortex of the rabbit. | Homogenates of rabbit renal cortex contained a water-soluble material with striking activity on smooth muscle derived from the rabbit aorta, rat stomach, and guinea pig ileum--but not rat colon or chick rectum. Evidence derived from the spectrum of its pharmacologic activity, the influence of specific competitive antag... | A smooth muscle active factor isolated from renal cortex of the rabbit. Homogenates of rabbit renal cortex contained a water-soluble material with striking activity on smooth muscle derived from the rabbit aorta, rat stomach, and guinea pig ileum--but not rat colon or chick rectum. Evidence derived from the spectrum of... | [
-0.04767300561070442,
-0.012352370657026768,
-0.009843814186751842,
0.02184595726430416,
0.04643385857343674,
-0.004228019155561924,
0.10987598448991776,
0.04499025642871857,
-0.04630277678370476,
-0.017039375379681587,
-0.022999167442321777,
-0.07307487726211548,
0.022009151056408882,
-0.... |
PMID:14509 | Specific desensitization (tachyphylaxis) of the guinea pig ileum to angiotensin II. | Tachyphylaxis to [Ile5]angiotensin II (angiotensin) in the isolated guinea pig ileum was found to be more severe when the Ca2+ concentration or the temperature of the medium were lowered, or when glucose was absent. Incubation with indomethacin or prostaglandin E2 did not affect the onset of tachyphylaxis or recovery f... | Specific desensitization (tachyphylaxis) of the guinea pig ileum to angiotensin II. Tachyphylaxis to [Ile5]angiotensin II (angiotensin) in the isolated guinea pig ileum was found to be more severe when the Ca2+ concentration or the temperature of the medium were lowered, or when glucose was absent. Incubation with indo... | [
-0.06809630990028381,
0.016076844185590744,
-0.004423805512487888,
0.0518493726849556,
0.050490524619817734,
-0.05776795372366905,
0.061197429895401,
0.016548894345760345,
-0.048550594598054886,
-0.03632836043834686,
0.039387643337249756,
-0.09498496353626251,
0.03290099650621414,
0.061536... |
PMID:14510 | Effect of nicotine on gastric acid secretion: evidence of electrogenic pump theory. | In vitro studies on H+ secretion, potential difference (PD), short-circuit current (Isc), and resistance across stripped mucosa of frog stomach in Cl-medium have shown that addition of nicotine in the serum bathing fluid caused a marked inhibition of the H+ secretory rate and an increase of PD and Isc without change of... | Effect of nicotine on gastric acid secretion: evidence of electrogenic pump theory. In vitro studies on H+ secretion, potential difference (PD), short-circuit current (Isc), and resistance across stripped mucosa of frog stomach in Cl-medium have shown that addition of nicotine in the serum bathing fluid caused a marked... | [
-0.043242473155260086,
-0.02042170614004135,
-0.0014414760516956449,
0.07106306403875351,
0.014546839520335197,
0.006708888337016106,
0.04407155141234398,
0.042176831513643265,
-0.020274341106414795,
-0.038378383964300156,
-0.0371825210750103,
-0.08998332172632217,
-0.043210987001657486,
0... |
PMID:14511 | Consequences of ventromedial hypothalamic lesions on metabolism of perfused rat liver. | Metabolism of perfused livers from control and ventromedial hypothalamus (VMH)-lesioned rats has been studied. To eliminate the possibility that observed metabolic abnormalities could be realted to hyperphagia, VMH-lesioned rats were placed on restricted diet matching that of controls. Ten days postoperatively, VMH-les... | Consequences of ventromedial hypothalamic lesions on metabolism of perfused rat liver. Metabolism of perfused livers from control and ventromedial hypothalamus (VMH)-lesioned rats has been studied. To eliminate the possibility that observed metabolic abnormalities could be realted to hyperphagia, VMH-lesioned rats were... | [
0.002726406091824174,
-0.0030695325694978237,
0.04011092334985733,
0.03505779057741165,
0.0011131268693134189,
-0.013646503910422325,
0.03170900419354439,
0.006006337236613035,
-0.03688283637166023,
0.0023118804674595594,
0.003661353839561343,
-0.049000296741724014,
0.02864643558859825,
0.... |
PMID:14512 | Uptake of K+ by frog gastric mucosa from submucosal side and acid secretory rate. | The K+ content in frog gastric mucosa (K+) was measured as a function of the submucosal K+ concentration ([K+sm]) in the absence of K+ on the mucosal side. The (K+) in HCO3- buffer with 95% O2-5% CO2 gas showed that the removal of external K+ induced a 27% K+ loss from the control value of 5 mM K+sm, that there was no... | Uptake of K+ by frog gastric mucosa from submucosal side and acid secretory rate. The K+ content in frog gastric mucosa (K+) was measured as a function of the submucosal K+ concentration ([K+sm]) in the absence of K+ on the mucosal side. The (K+) in HCO3- buffer with 95% O2-5% CO2 gas showed that the removal of externa... | [
-0.04045293480157852,
-0.05372617021203041,
0.045199088752269745,
0.01770339347422123,
0.025499090552330017,
-0.04155484959483147,
0.04074731096625328,
-0.010633844882249832,
-0.03755412623286247,
0.01976531371474266,
-0.010942455381155014,
-0.1361141949892044,
0.004129842389374971,
-0.010... |
PMID:14513 | Intracellular pH in hypoxic smooth muscle. | Hypoxia impairs contractility in canine tracheal smooth muscle (TSM). This is attributed to intracellular lactacidosis. The present studies were undertaken to confirm this. Lactate was found to be significantly increased in hypoxic TSM (65.36 +/- 7.37 mg/100 g wet tissue), compared to normoxic (29.83 +/- 5.05). Intrace... | Intracellular pH in hypoxic smooth muscle. Hypoxia impairs contractility in canine tracheal smooth muscle (TSM). This is attributed to intracellular lactacidosis. The present studies were undertaken to confirm this. Lactate was found to be significantly increased in hypoxic TSM (65.36 +/- 7.37 mg/100 g wet tissue), com... | [
-0.013682589866220951,
-0.045850902795791626,
0.034926366060972214,
0.07338405400514603,
0.01446722261607647,
-0.00618944875895977,
0.06873384863138199,
0.07409913837909698,
-0.015089490450918674,
0.013559184968471527,
-0.010636290535330772,
-0.09222524613142014,
-0.006933496333658695,
0.0... |
PMID:14514 | Neuroleptic drug levels and therapeutic response: preliminary observations with red blood cell bound butaperazine. | The authors studied neuroleptic concentration-therapeutic response curves for butaperazine (BPZ), a piperazine phenothiazine, in 10 schizophrenic patients during the first 12 days of treatment. BPZ bound to red blood cells (RBC) was more strongly correlated with therapeutic response than was plasma BPZ. RBC BPZ concent... | Neuroleptic drug levels and therapeutic response: preliminary observations with red blood cell bound butaperazine. The authors studied neuroleptic concentration-therapeutic response curves for butaperazine (BPZ), a piperazine phenothiazine, in 10 schizophrenic patients during the first 12 days of treatment. BPZ bound t... | [
-0.07902267575263977,
0.03631637245416641,
-0.02556963451206684,
0.02495555952191353,
-0.024718474596738815,
0.024830030277371407,
0.08819462358951569,
0.0519767664372921,
-0.012738524936139584,
-0.06494170427322388,
-0.010792410001158714,
-0.024250661954283714,
-0.014337749220430851,
0.04... |
PMID:14516 | Systemic artery--pulmonary artery communication in Takayasu's arteritis. | Four cases of Takayasu's arteritis in which systemic artery-pulmonary artery communication is demonstrated on thoracic aortography are presented. Pulmonary arterial involvement in Takayasu's arteritis seems to be more frequent than generally appreciated (12% in the present series). Demonstration of the communication in... | Systemic artery--pulmonary artery communication in Takayasu's arteritis. Four cases of Takayasu's arteritis in which systemic artery-pulmonary artery communication is demonstrated on thoracic aortography are presented. Pulmonary arterial involvement in Takayasu's arteritis seems to be more frequent than generally appre... | [
-0.014049052260816097,
-0.0019148699939250946,
-0.019616149365901947,
-0.007664394564926624,
-0.012968326918780804,
-0.014241337776184082,
0.04104792699217796,
0.072871133685112,
-0.02159799076616764,
0.024702832102775574,
-0.037269268184900284,
-0.06589977443218231,
-0.018430013209581375,
... |
PMID:14518 | [Effect of run-training and run-stress on glucose assimilation and insulin release in rats of different age (author's transl)]. | 82 male rats of different age have been investigated after a definitive run-training, after a run-training with subsequent run-stress and after a run-stress without run-training. An intravenous glucose tolerance test has been done measuring glucose and insulin serum levels before and after i.v. glucose application. Dat... | [Effect of run-training and run-stress on glucose assimilation and insulin release in rats of different age (author's transl)]. 82 male rats of different age have been investigated after a definitive run-training, after a run-training with subsequent run-stress and after a run-stress without run-training. An intravenou... | [
-0.003883747849613428,
0.013533192686736584,
0.041531093418598175,
0.033097293227910995,
0.031040724366903305,
0.037792645394802094,
0.008220145478844643,
-0.0301712304353714,
-0.05635610595345497,
-0.07103370130062103,
0.01892968639731407,
-0.061225537210702896,
-0.015454809181392193,
0.0... |
PMID:14519 | [Investigations on LH and FSH serum levels before and after application of synthetic LH-releasing-hormone in healthy men of different age]. | 50 male healthy volunteers of different age had measurements of plasma luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Basal levels of LH and FSH as well as maximal release of both hormones after i.v. application of 25 mug of synthetical LH-releasing hormone have been done. Results demonstrate an incre... | [Investigations on LH and FSH serum levels before and after application of synthetic LH-releasing-hormone in healthy men of different age]. 50 male healthy volunteers of different age had measurements of plasma luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Basal levels of LH and FSH as well as maxima... | [
0.017915690317749977,
0.04084444418549538,
0.015770452097058296,
-0.008151327259838581,
0.016047490760684013,
0.02460882067680359,
0.023581381887197495,
-0.00355894910171628,
-0.07149039953947067,
-0.026767311617732048,
0.017719507217407227,
-0.05625532940030098,
0.015399394556879997,
0.08... |
PMID:14520 | [Sexual hormones in ageing males (author's transl)]. | Alterations of sexual hormones in plasma of ageing males occur between the 50th and 60th year of life with individual variations: 1. Decreased values of testosterone in plasma and a poor response to gonadotrophins demonstrate a diminished synthesizing capacity of the testes in old men. 2. The decreased testosterone pla... | [Sexual hormones in ageing males (author's transl)]. Alterations of sexual hormones in plasma of ageing males occur between the 50th and 60th year of life with individual variations: 1. Decreased values of testosterone in plasma and a poor response to gonadotrophins demonstrate a diminished synthesizing capacity of the... | [
0.05377040058374405,
0.07667448371648788,
-0.012414909899234772,
-0.005323839373886585,
0.027378808706998825,
0.012347367592155933,
0.05562081187963486,
-0.009375465102493763,
-0.07070264220237732,
-0.0401320718228817,
-0.02651812508702278,
-0.04264692962169647,
0.04766026884317398,
0.0715... |
PMID:14521 | [Geriatric change of thyroid function and thyroid diseases (author's transl)]. | The geriatric changes of thyroid function in healthy individuals are relatively low; therefore it is not necessary to take it into consideration for routine diagnostic work. Thyroid diseases show an increase with age and also a change of the clinical picture. Therefore, and because of being superimposed by symptoms of ... | [Geriatric change of thyroid function and thyroid diseases (author's transl)]. The geriatric changes of thyroid function in healthy individuals are relatively low; therefore it is not necessary to take it into consideration for routine diagnostic work. Thyroid diseases show an increase with age and also a change of the... | [
0.027367932721972466,
0.01495271921157837,
0.07852207869291306,
-0.008583049289882183,
0.019123613834381104,
-0.005698989611119032,
0.08682319521903992,
0.05583216995000839,
-0.05954931676387787,
-0.01621832512319088,
0.012769890949130058,
-0.025585386902093887,
-0.037551503628492355,
0.03... |
PMID:14522 | Functional changes of the aging rat retina in relation to the modifications of the ERG components. | the intact eye of Wistar rat was stimulated with continual periodic light signals in the range of 0,001-500 lux and from 0,01 cps. up to the fusionfrequency. Using square-wave light stimuli of the frequency range from 0,01 to 0,1 cps. and intensity diapason of 0,1-1,0 lux the scotopic electroretinogram (ERG) consists o... | Functional changes of the aging rat retina in relation to the modifications of the ERG components. the intact eye of Wistar rat was stimulated with continual periodic light signals in the range of 0,001-500 lux and from 0,01 cps. up to the fusionfrequency. Using square-wave light stimuli of the frequency range from 0,0... | [
-0.033837009221315384,
-0.03097584657371044,
0.007650645449757576,
0.015374809503555298,
0.04274437949061394,
0.05052729323506355,
0.06778395175933838,
0.01814599148929119,
-0.06326156109571457,
0.004996377509087324,
0.028159180656075478,
-0.043747998774051666,
-0.04018303006887436,
0.0310... |
PMID:14523 | [Assessment of the biological age in the animal-experiment (author's transl)]. | Experimental investigations of internal and external factors presumably influencing the aging process require an objective assessment of the biological age or vitality respectively by means of as many age parameters as possible. Using the rat, a valuable test animal in experimental gerontology, whose life expectancy of... | [Assessment of the biological age in the animal-experiment (author's transl)]. Experimental investigations of internal and external factors presumably influencing the aging process require an objective assessment of the biological age or vitality respectively by means of as many age parameters as possible. Using the ra... | [
-0.027947625145316124,
0.014179953373968601,
0.004311460070312023,
-0.02529974840581417,
0.00336813204921782,
0.028878429904580116,
0.05807925760746002,
0.039021383970975876,
-0.07732177525758743,
-0.039169009774923325,
0.031164491549134254,
-0.05485263839364052,
-0.031770817935466766,
0.0... |
PMID:14524 | [Investigation of memory in experimental gerontology (author's transl)]. | The possible transfer of learning performance by proteins and ribonucleic acids was studied. 140 male Sprague-Dawley rats aged 3 months and 68 aged 20 months were used. Proteins and ribonucleic acids were isolated from the brains of trained and untrained rats aged 3 months. The difference in learning performance was te... | [Investigation of memory in experimental gerontology (author's transl)]. The possible transfer of learning performance by proteins and ribonucleic acids was studied. 140 male Sprague-Dawley rats aged 3 months and 68 aged 20 months were used. Proteins and ribonucleic acids were isolated from the brains of trained and un... | [
-0.02245277911424637,
-0.009966804645955563,
-0.00721605634316802,
-0.0009943178156390786,
-0.00207258528098464,
0.02840709313750267,
0.062075067311525345,
-0.005321198143064976,
-0.03969758003950119,
0.01817571371793747,
0.0197931956499815,
-0.0617300383746624,
0.020030682906508446,
0.052... |
PMID:14525 | [Paranoid syndromes in the involution (author's transl)]. | Conditions of outbreak and chronification of paranoid syndromes, including the existence of an "axial syndrome" and behaviour theories are hypothetically summarized. The individual characteristics of patients with the first paranoid symptoms during involution appear to depend mainly on three factors: the theme of the d... | [Paranoid syndromes in the involution (author's transl)]. Conditions of outbreak and chronification of paranoid syndromes, including the existence of an "axial syndrome" and behaviour theories are hypothetically summarized. The individual characteristics of patients with the first paranoid symptoms during involution ap... | [
0.004681360442191362,
0.0264988262206316,
-0.0004540489171631634,
0.035602014511823654,
-0.03340844437479973,
0.04036147519946098,
0.10734636336565018,
0.03299188241362572,
0.039610061794519424,
-0.057045113295316696,
0.047205183655023575,
-0.05400102213025093,
0.006002192851155996,
0.0442... |
PMID:14526 | [Genetic aspects of aging (author's transl)]. | The experimental results indicating a primary genetic cause of aging and some diseases of the old age (cancer, arteriosclerosis, immune deficiency, autoimmune diseases) are summarized under two aspects: 1) The genetic influence is determined during the differentiation and development phase of the organism, whereby the ... | [Genetic aspects of aging (author's transl)]. The experimental results indicating a primary genetic cause of aging and some diseases of the old age (cancer, arteriosclerosis, immune deficiency, autoimmune diseases) are summarized under two aspects: 1) The genetic influence is determined during the differentiation and d... | [
0.013386842794716358,
0.027073651552200317,
-0.0008484041318297386,
-0.018433956429362297,
0.028692880645394325,
0.03742353990674019,
0.046965718269348145,
0.05819326639175415,
-0.09012125432491302,
-0.06637993454933167,
0.0290799792855978,
-0.02395465411245823,
0.0013445590157061815,
0.04... |
PMID:14527 | [Study of age and sex dependance in renal clearances with radioisotopes (author's transl)]. | In 85 patients between 15 and 95 years of age (40 male patients and 45 females) without any signs of renal disease (concentration of serum creatinine below 1,4 mg/100ml, normal diastolic blood pressure and normal urine analysis) a highly significant negative correlation was found between glomerular filtration rate (GFR... | [Study of age and sex dependance in renal clearances with radioisotopes (author's transl)]. In 85 patients between 15 and 95 years of age (40 male patients and 45 females) without any signs of renal disease (concentration of serum creatinine below 1,4 mg/100ml, normal diastolic blood pressure and normal urine analysis)... | [
0.005582895595580339,
0.012131600640714169,
0.007821796461939812,
-0.0047639827243983746,
0.01199770625680685,
-0.003536418080329895,
0.07388045638799667,
0.056097906082868576,
-0.04311388358473778,
0.003799222642555833,
0.037758927792310715,
-0.06152728199958801,
0.011193674057722092,
0.0... |
PMID:14528 | [The significance of experimental gerontology for clinical geriatrics (author's transl)]. | Aging is a physiological process. The experimental gerontology is substantially a purely theoretical science. In the future, however, it will attain increasingly more significance for many fields of medicine. After presenting a survey covering the most important theories of aging it is shortly entered into the efforts ... | [The significance of experimental gerontology for clinical geriatrics (author's transl)]. Aging is a physiological process. The experimental gerontology is substantially a purely theoretical science. In the future, however, it will attain increasingly more significance for many fields of medicine. After presenting a su... | [
-0.043498918414115906,
0.051658567041158676,
0.014552013948559761,
0.006323962938040495,
0.02786567620933056,
0.010531749576330185,
0.018464429304003716,
0.04353261739015579,
-0.0287290271371603,
-0.034653495997190475,
0.007119651418179274,
-0.04803773760795593,
-0.036765020340681076,
0.07... |
PMID:14530 | [A serogenetic approach to the study of Alzheimer's disease (author's transl)]. | The analysis of 15 hereditary controlled blood characteristics in 57 Alzheimer-patients revealed abnormalities in the distribution of ABO-blood-groups and phenotypes in the third component of complement system. These data indicate that the phenogenesis of the Alzheimer syndrome is multiconditional and is obviously infl... | [A serogenetic approach to the study of Alzheimer's disease (author's transl)]. The analysis of 15 hereditary controlled blood characteristics in 57 Alzheimer-patients revealed abnormalities in the distribution of ABO-blood-groups and phenotypes in the third component of complement system. These data indicate that the ... | [
-0.04386464133858681,
0.05488487705588341,
-0.03176888823509216,
0.012560894712805748,
-0.020439032465219498,
0.019652092829346657,
0.09604394435882568,
0.03380604088306427,
0.0110806068405509,
-0.019578509032726288,
0.011371923610568047,
-0.07085972279310226,
-0.021162355318665504,
0.0263... |
PMID:14531 | [The effect of prednisolone on the development of the galactosamine hepatitis of young and old rats (author's transl)]. | The present work reports on kinetic and morphological studies of one hundred female albino rats after the administration of galactosamine and galactosamine and prednisolone. The results demonstrate a significant higher increase of the serum transaminasess got and gpt in the older than in the younger rats as well as a p... | [The effect of prednisolone on the development of the galactosamine hepatitis of young and old rats (author's transl)]. The present work reports on kinetic and morphological studies of one hundred female albino rats after the administration of galactosamine and galactosamine and prednisolone. The results demonstrate a ... | [
-0.0267783235758543,
-0.004207494668662548,
0.07215248793363571,
-0.0028195087797939777,
0.0073243072256445885,
-0.038204122334718704,
0.03011712059378624,
0.027524754405021667,
-0.09322571754455566,
-0.0744597315788269,
0.02807895466685295,
-0.039535652846097946,
-0.03636180981993675,
0.0... |
PMID:14532 | [Age-dependent changes of hypophysis-thyroid - regulation (author's transl)]. | In health men and women different age total thyroxine, free thyroxine-binding-capacity, total triiodothyronine as well as TSH in serum before and after intravenous application of 500 mcg synthetic thyrothropine-releasing-hormone (TRH) were controlled. The investigations have shown: 1. With increasing age total thyroxin... | [Age-dependent changes of hypophysis-thyroid - regulation (author's transl)]. In health men and women different age total thyroxine, free thyroxine-binding-capacity, total triiodothyronine as well as TSH in serum before and after intravenous application of 500 mcg synthetic thyrothropine-releasing-hormone (TRH) were co... | [
0.009935710579156876,
0.050372347235679626,
0.03987761214375496,
0.04547993093729019,
-0.01566392369568348,
0.030974801629781723,
0.04634788632392883,
-0.015425413846969604,
-0.09945966303348541,
-0.025901390239596367,
-0.0007980321533977985,
-0.060222841799259186,
0.008561241440474987,
0.... |
PMID:14533 | [Problemss of tending to chronicity of diseases in geriatrics (author's transl)]. | The most important alterations of the old age are mentioned. They have a great influence on the behaviour of the elderly in a hospital. Charactersitic behaviour patterns at admission, during hospitalization and at dismission are pointed out. Multimorbidity should not cause a thoughtless and highly technical work-up. Re... | [Problemss of tending to chronicity of diseases in geriatrics (author's transl)]. The most important alterations of the old age are mentioned. They have a great influence on the behaviour of the elderly in a hospital. Charactersitic behaviour patterns at admission, during hospitalization and at dismission are pointed o... | [
-0.03252631798386574,
0.05044640600681305,
0.0321282260119915,
-0.023455452173948288,
-0.002953273244202137,
0.009039160795509815,
0.03394502401351929,
0.02622642181813717,
-0.038169559091329575,
-0.022024985402822495,
-0.02611285261809826,
-0.0038575856015086174,
-0.08687601238489151,
0.0... |
PMID:14534 | [Medical treatment and rehabilitation measures for the elderly--discussion of the financial problems involved (author's transl)]. | The National Pension Insurance and Health Insurance Schemes up to now share the expenses of health insurance for the elderly. The shares to be carried by each body are again and again subject to political discussion. Since nursing home care is up to now not accepted as being an integral part of health care, the social ... | [Medical treatment and rehabilitation measures for the elderly--discussion of the financial problems involved (author's transl)]. The National Pension Insurance and Health Insurance Schemes up to now share the expenses of health insurance for the elderly. The shares to be carried by each body are again and again subjec... | [
-0.057289645075798035,
-0.020480168983340263,
-0.018799103796482086,
-0.019467730075120926,
0.04554251581430435,
0.003017467213794589,
0.01582111045718193,
0.009551815688610077,
-0.03280862420797348,
-0.02596180886030197,
0.03312044218182564,
0.02262653410434723,
-0.03321779891848564,
0.06... |
PMID:14535 | [Clinical use of a thermal method for measuring peripheral blood flow according to A.M. Baptista (author's transl)]. | Measurement of peripheral circulation according to Baptista is discussed and its applicability in clinical work demonstrated. Examples are given showing changes following peroral treatment with inositol niacinate and intra-arterial injection of carbon dioxide. | [Clinical use of a thermal method for measuring peripheral blood flow according to A.M. Baptista (author's transl)]. Measurement of peripheral circulation according to Baptista is discussed and its applicability in clinical work demonstrated. Examples are given showing changes following peroral treatment with inositol ... | [
-0.012924635782837868,
0.03724467009305954,
0.04969785362482071,
-0.0039491914212703705,
-0.011277209967374802,
-0.029654329642653465,
0.0895952433347702,
0.029390107840299606,
0.01075365673750639,
-0.03322989493608475,
-0.0025611603632569313,
-0.06510341167449951,
-0.023936431854963303,
0... |
PMID:14536 | [Peculiarities of unconditioned and conditioned reflex stimuli effects on secretory function of gastric glands in elderly and senile people (author's transl)]. | For understanding age peculiarities of gastric secretory function in aging.tory function in aging.tory function regulation, the investigation of nervous influences on gastric secretion is of importance. With this end in view the unconditioned reflex stimulus- the tube with rubber balloon, containing 10 ml of water and ... | [Peculiarities of unconditioned and conditioned reflex stimuli effects on secretory function of gastric glands in elderly and senile people (author's transl)]. For understanding age peculiarities of gastric secretory function in aging.tory function in aging.tory function regulation, the investigation of nervous influen... | [
0.02045312337577343,
0.0026760592591017485,
0.001491522416472435,
0.05038094148039818,
0.02355286478996277,
0.025611739605665207,
0.09143021702766418,
0.017475418746471405,
-0.05936674028635025,
-0.060540635138750076,
-0.028623003512620926,
-0.05839131399989128,
-0.017548777163028717,
0.04... |
PMID:14537 | [Incorporation of 14-C-Glycine during galactosamine hepatitis of young and old rats (author's transl)a*]. | The present work reports on incorporation of 14-Cglycine in the proteins of three liver fractions after the application of D-Galactosamine and D-Galactosamine + Prednisolone. 164 females albino rats were used in the experiments. The results demonstrate a higher rate of glycine incorporation in thirty months than in six... | [Incorporation of 14-C-Glycine during galactosamine hepatitis of young and old rats (author's transl)a*]. The present work reports on incorporation of 14-Cglycine in the proteins of three liver fractions after the application of D-Galactosamine and D-Galactosamine + Prednisolone. 164 females albino rats were used in th... | [
-0.04721391573548317,
-0.015021341852843761,
0.046371299773454666,
-0.028713464736938477,
-0.039940547198057175,
-0.04332401603460312,
0.024987919256091118,
0.01873030699789524,
-0.07563149929046631,
-0.05185534805059433,
0.033378344029188156,
-0.06300463527441025,
-0.013575250282883644,
0... |
PMID:14538 | [The correlations between aging and drug effects (author's transl)]. | Four examples (Methamphetamine, Testosterone, Caffeine, Cysteamine) have demonstrated that the response of the organism to a drug is primarily dependent upon the functional status of the organ concerned. If this functional status changes with age, then accordingly the reaction to the drug also changes. If, however, one... | [The correlations between aging and drug effects (author's transl)]. Four examples (Methamphetamine, Testosterone, Caffeine, Cysteamine) have demonstrated that the response of the organism to a drug is primarily dependent upon the functional status of the organ concerned. If this functional status changes with age, the... | [
-0.017620151862502098,
0.03947233036160469,
0.020085420459508896,
0.01999920792877674,
0.041809722781181335,
0.025507962331175804,
0.1088329553604126,
0.047704655677080154,
-0.0707102119922638,
-0.035503000020980835,
0.03260073438286781,
0.045857228338718414,
-0.040224749594926834,
0.06322... |
PMID:14539 | [Transitional phases in human development (author's transl)]. | Transitional phases in the course of Human Development which divide the course of development into different steps, have been searched far from the old. These transitional phases are very often seen to be at least initiated by physical resp. biological changes and accompanied by psychological or mental changes. The res... | [Transitional phases in human development (author's transl)]. Transitional phases in the course of Human Development which divide the course of development into different steps, have been searched far from the old. These transitional phases are very often seen to be at least initiated by physical resp. biological chang... | [
-0.0007868636748753488,
0.027288248762488365,
0.041888732463121414,
-0.006389671936631203,
0.00012053028331138194,
0.055013954639434814,
0.03742903470993042,
-0.001645419280976057,
0.013027663342654705,
-0.05338656157255173,
0.07491060346364975,
-0.008701043203473091,
-0.011391903273761272,
... |
PMID:14540 | [Biological oriented research in gerontopsychiatrie (author's transl)]. | Possible biological oriented research in geronto-psychiatry is discussed in relation to dementias. The discrimination between the various forms as well as against normal aging is dealt with. Reference is given to results of studies correlating clinical, neuropathological and neurophysiological date. | [Biological oriented research in gerontopsychiatrie (author's transl)]. Possible biological oriented research in geronto-psychiatry is discussed in relation to dementias. The discrimination between the various forms as well as against normal aging is dealt with. Reference is given to results of studies correlating clin... | [
-0.023907946422696114,
0.07548446953296661,
-0.0033763519022613764,
0.022253939881920815,
0.04928307607769966,
0.045540135353803635,
0.03357614204287529,
-0.004748692270368338,
-0.01338267233222723,
-0.06302200257778168,
0.01952734962105751,
0.01401817798614502,
-0.0628141462802887,
0.0453... |
PMID:14541 | [Multidimensional pharmacopsychiatry in gerontopsychiatry: studies on the therapy with tricyclic antidepressant drugs (author's transl)]. | A Concept for the multidimensional assessment and correlation of serum level and outcome of therapy with psychomopharmaca with chemical, psychological, psychophysiological, electroencephalographical and clinical methods is shown. It is possible by this method to correlate clinical outcome to serum level and effect of t... | [Multidimensional pharmacopsychiatry in gerontopsychiatry: studies on the therapy with tricyclic antidepressant drugs (author's transl)]. A Concept for the multidimensional assessment and correlation of serum level and outcome of therapy with psychomopharmaca with chemical, psychological, psychophysiological, electroen... | [
-0.03840922191739082,
0.03327292203903198,
0.02867160178720951,
0.009750519879162312,
-0.003994823433458805,
-0.006207064725458622,
0.06198786571621895,
0.017976170405745506,
-0.018369734287261963,
-0.07284487783908844,
0.029696568846702576,
-0.023557040840387344,
-0.004388348665088415,
0.... |
PMID:14542 | [Patients and their diseases in a geriatric hospital (author's transl)]. | Report on patients and their problems of a hospital of chronic diseases. Geriatric departments, part of clinics of acute diseases should treat not only patients without real chance for rehabilitation or discharge. Most of the diseases of elder persons are such of the arterial system, especially of the cerebral and coro... | [Patients and their diseases in a geriatric hospital (author's transl)]. Report on patients and their problems of a hospital of chronic diseases. Geriatric departments, part of clinics of acute diseases should treat not only patients without real chance for rehabilitation or discharge. Most of the diseases of elder per... | [
-0.015016556717455387,
0.04098338261246681,
0.00665828725323081,
0.0014365685638040304,
0.020175645127892494,
-0.04609048739075661,
0.07054553180932999,
0.022123022004961967,
-0.03252987191081047,
0.014667186886072159,
0.0012087550712749362,
-0.017057806253433228,
-0.021997451782226562,
0.... |
PMID:14544 | [Indications for orthopedic procedures in old people (author's transl)]. | Advancements in general medicine and anesthesiology have enabled surgical procedures in old people with diminished risks. With reference to special problems the absolute indication for orthopedic procedures particularly for the old can be demonstrated. | [Indications for orthopedic procedures in old people (author's transl)]. Advancements in general medicine and anesthesiology have enabled surgical procedures in old people with diminished risks. With reference to special problems the absolute indication for orthopedic procedures particularly for the old can be demonstr... | [
0.0035114509519189596,
0.004619579296559095,
0.05308448523283005,
-0.030378829687833786,
-0.03646688535809517,
0.058541346341371536,
0.043083254247903824,
0.049571409821510315,
-0.05421154201030731,
-0.01595369167625904,
-0.004728770814836025,
0.041321512311697006,
-0.051520708948373795,
0... |
PMID:14545 | Model systems for studies on cellular basis of organ ageing. | The cellular basis of the age-related decline in the functional capacity of many mammalian organs is still poorly understood. In this paper, the rat liver is presented as a promising model for studying cellular phenomena underlying organ ageing. The recent development of methods for isolation and purification of parenc... | Model systems for studies on cellular basis of organ ageing. The cellular basis of the age-related decline in the functional capacity of many mammalian organs is still poorly understood. In this paper, the rat liver is presented as a promising model for studying cellular phenomena underlying organ ageing. The recent de... | [
-0.01654001884162426,
-0.03883741796016693,
0.0016620587557554245,
-0.011395330540835857,
0.031184179708361626,
-0.025852421298623085,
0.0802035927772522,
0.027822205796837807,
-0.0700027197599411,
-0.00008230999810621142,
0.02499154768884182,
-0.06472006440162659,
-0.007253615651279688,
0... |
PMID:14546 | Age-dependent increase of intranuclear monovalent electrolytes as revealed by quantitative energy dispersive x-ray microanalysis. | The concentration of univalent electrolytes in the cell nucleus and cytoplasm of the big neurons of the brain and in hepatocytes was established in young, mature and old rats by means of microanalysis with X-rays. It was demonstrated that the Na+ and Cl-- content increases with aging in both tissues, while K+ increases... | Age-dependent increase of intranuclear monovalent electrolytes as revealed by quantitative energy dispersive x-ray microanalysis. The concentration of univalent electrolytes in the cell nucleus and cytoplasm of the big neurons of the brain and in hepatocytes was established in young, mature and old rats by means of mic... | [
-0.035232339054346085,
-0.040952011942863464,
0.03976558893918991,
-0.0037560404743999243,
0.03312127664685249,
0.012611954472959042,
0.044551290571689606,
-0.031917814165353775,
-0.04182308167219162,
-0.018386032432317734,
0.04025357961654663,
-0.04498930647969246,
-0.028361337259411812,
... |
PMID:14547 | On the relationship between the perichromatin granules and cellular ageing as well as cell differentiation. | Current hypotheses ascribe the role of pre-RNA storage or transport structures to the perichromatin granules. Their numerical density is directly related to the transcription activity of the nucleus. The perichromatin granules (P.K.) can be demonstrated in ultrathin sections with the stain used by Bernhard (1969) for r... | On the relationship between the perichromatin granules and cellular ageing as well as cell differentiation. Current hypotheses ascribe the role of pre-RNA storage or transport structures to the perichromatin granules. Their numerical density is directly related to the transcription activity of the nucleus. The perichro... | [
-0.014942379668354988,
-0.04491721838712692,
0.011051101610064507,
-0.04925619065761566,
-0.01763327419757843,
0.032976895570755005,
0.022392768412828445,
-0.01283835805952549,
-0.010780679062008858,
-0.01432720199227333,
-0.005708817392587662,
-0.06989444047212601,
0.04165803641080856,
0.... |
PMID:14548 | On the reversibility of some cytological ageing parameters of rat brain cells by phytohemagglutinin. | It has been shown that the thermal stability of DNA in the brain cortical cells increases with the age. At the same time, the number of perichromatin granules being connected in some way to the messenger RNA synthesis and transport of the interphase nuclei, decreases in the same cells. In vivo treatment of the old anim... | On the reversibility of some cytological ageing parameters of rat brain cells by phytohemagglutinin. It has been shown that the thermal stability of DNA in the brain cortical cells increases with the age. At the same time, the number of perichromatin granules being connected in some way to the messenger RNA synthesis a... | [
-0.05025649070739746,
-0.016756800934672356,
0.0013102807570248842,
0.0019660063553601503,
0.002223918680101633,
0.020069852471351624,
0.051647674292325974,
-0.021331192925572395,
-0.0853172019124031,
-0.013296257704496384,
-0.021469248458743095,
-0.038217607885599136,
0.022887814790010452,
... |
PMID:14549 | [Chromosomal investigations in two age groups of human females]. | Chromosomal analysis was performed in cultured lymphocytes from 32 old (ages 76-85, abbr. A) and 31 young (ages 15-20, abbr. J) patients, who were representative for a great part of the "normal" female population of the same age. In regard to culture time (48 and 72 hours) each age group was divided into two halves; 15... | [Chromosomal investigations in two age groups of human females]. Chromosomal analysis was performed in cultured lymphocytes from 32 old (ages 76-85, abbr. A) and 31 young (ages 15-20, abbr. J) patients, who were representative for a great part of the "normal" female population of the same age. In regard to culture time... | [
-0.025886889547109604,
-0.01365252211689949,
0.02890896610915661,
0.012424946762621403,
0.01200277078896761,
0.01722741313278675,
-0.00230349856428802,
0.026044541969895363,
-0.03284255787730217,
-0.065621517598629,
0.04082748293876648,
-0.049169041216373444,
0.018037188798189163,
-0.00925... |
PMID:14550 | Age changes of turnover rates and subfraction composition of rat liver and spleen histones. | Histones from tissues of young and old rats have been compared. Lysine-rich F1 histone was found to be the only one which is tissue specific and whose subfraction pattern changes in old cells. The comparison of turnover rates of different histones from liver and spleen, measured by the level of 3H-leucine incorporation... | Age changes of turnover rates and subfraction composition of rat liver and spleen histones. Histones from tissues of young and old rats have been compared. Lysine-rich F1 histone was found to be the only one which is tissue specific and whose subfraction pattern changes in old cells. The comparison of turnover rates of... | [
-0.0352984219789505,
-0.04172628000378609,
0.026243651285767555,
-0.02933831885457039,
-0.01904563046991825,
0.02007378451526165,
0.04970986768603325,
0.024303622543811798,
-0.02690553292632103,
-0.000025858982553472742,
0.014234394766390324,
-0.06509154289960861,
0.024869544431567192,
0.0... |
PMID:14551 | [On the biophysical interpretation of ageing-factors (author's transl)]. | The ageing-factor is a measure for the rate of ageing. In the model of vitality the error rate mu corresponds to the ageing-factor. The ageing-factors of several physical functions can be determined from the ascent of decrease of these functions. The standardized ageing-factors of the considered physiological functions... | [On the biophysical interpretation of ageing-factors (author's transl)]. The ageing-factor is a measure for the rate of ageing. In the model of vitality the error rate mu corresponds to the ageing-factor. The ageing-factors of several physical functions can be determined from the ascent of decrease of these functions. ... | [
-0.07696500420570374,
0.035493072122335434,
0.0613744780421257,
0.015459691174328327,
0.06632057577371597,
-0.01864480786025524,
0.08460556715726852,
-0.029060645028948784,
-0.03383799269795418,
0.027662428095936775,
0.037430379539728165,
-0.11121770739555359,
0.03942662850022316,
0.035293... |
PMID:14552 | [Free amino-acids of the plasma in atherosclerotic patients (author's transl)]. | 18 free amino-acids have been valuated in a group of patients recovering from myocardial infarction dating more than one year back and in another group of healthy active athlets. In the group of the ill persons the mean values of the following amino-acids were significantly higher: Arginine, asparagine-acid, phenylalan... | [Free amino-acids of the plasma in atherosclerotic patients (author's transl)]. 18 free amino-acids have been valuated in a group of patients recovering from myocardial infarction dating more than one year back and in another group of healthy active athlets. In the group of the ill persons the mean values of the follow... | [
-0.05905172601342201,
0.05470743030309677,
-0.04045768827199936,
0.08430510014295578,
-0.040257446467876434,
0.004500347655266523,
0.055564284324645996,
0.026492061093449593,
-0.012898032553493977,
-0.006865954492241144,
0.05975320190191269,
-0.0923985168337822,
0.019404683262109756,
-0.01... |
PMID:14557 | Halothane depresses baroreflex control of heart rate in man. | Baroreflex control of heart rate was determined during three awake control situations and during two depths of halothane anesthesia in man. Baroreflex function was quantiated by calculating the pressor test slope from the R-R interval change on the ECG produced by a pharmacologically induced pressor response. During th... | Halothane depresses baroreflex control of heart rate in man. Baroreflex control of heart rate was determined during three awake control situations and during two depths of halothane anesthesia in man. Baroreflex function was quantiated by calculating the pressor test slope from the R-R interval change on the ECG produc... | [
-0.021633818745613098,
0.057115599513053894,
0.046598855406045914,
0.05963221937417984,
-0.015904631465673447,
0.05369510501623154,
0.040884025394916534,
0.025825684890151024,
0.013462643139064312,
-0.04655979201197624,
-0.03659510239958763,
-0.029266556724905968,
-0.023613151162862778,
-0... |
PMID:14563 | [Neuroleptics and microsurgery of the ear]. | In the field of research into new methods, we attempted to determine the primary effect, i.e. neuroleptic effects following the intensity of reactions to stimulation in patients undergoing microsurgery of the ear, comparing in particular the quantities of analgesic necessary and used during general anesthetic to ensure... | [Neuroleptics and microsurgery of the ear]. In the field of research into new methods, we attempted to determine the primary effect, i.e. neuroleptic effects following the intensity of reactions to stimulation in patients undergoing microsurgery of the ear, comparing in particular the quantities of analgesic necessary ... | [
0.0021248760167509317,
0.01138413418084383,
0.03403652086853981,
-0.008890535682439804,
-0.01938624680042267,
0.04818088188767433,
0.07807540148496628,
0.050056543201208115,
-0.029512716457247734,
-0.033008843660354614,
0.018754957243800163,
-0.001223669620230794,
-0.022843671962618828,
0.... |
PMID:14564 | [Controlled arterial hypotension produced by nitroprusside combined with neuroleptics]. | Ganglioplegic drugs, including trimetaphan, have been imperfect agents of arterial hypotension, liable to produce tachyphylaxis, and not blocking intercurrent attacks of adrenergic hypertension the dose is inconstant and reversibility sometimes doubtful. The association of neuroleptics, in particulier promazines, permi... | [Controlled arterial hypotension produced by nitroprusside combined with neuroleptics]. Ganglioplegic drugs, including trimetaphan, have been imperfect agents of arterial hypotension, liable to produce tachyphylaxis, and not blocking intercurrent attacks of adrenergic hypertension the dose is inconstant and reversibili... | [
-0.07670111209154129,
0.011543813161551952,
-0.03339266777038574,
0.013439475558698177,
0.0027545427437871695,
-0.0037155316676944494,
0.06055688485503197,
0.015376471914350986,
-0.02112124301493168,
-0.05015788599848747,
0.01806838996708393,
0.00006937197758816183,
0.027181636542081833,
0... |
PMID:14565 | [Neuroleptanalgesia as the anesthesia in pediatric surgery]. | In work carried out over a period of two years in the department of anesthetics and intensive care of the Saint-Etienne University Hospital, the authors report their experience of neuroleptanalgesia using droperidol-dextromoramide in children in 104 cases. The observations may be divided up into 2 groups: - 1 group of ... | [Neuroleptanalgesia as the anesthesia in pediatric surgery]. In work carried out over a period of two years in the department of anesthetics and intensive care of the Saint-Etienne University Hospital, the authors report their experience of neuroleptanalgesia using droperidol-dextromoramide in children in 104 cases. Th... | [
-0.005706372670829296,
-0.043895233422517776,
0.030120300129055977,
-0.006257038097828627,
-0.035528626292943954,
0.003642007941380143,
0.03902336210012436,
0.06910312920808792,
-0.04141650348901749,
-0.011925972998142242,
0.004665438085794449,
0.06216753274202347,
-0.018911542370915413,
0... |
PMID:14566 | [Place of neuroleptics in geriatric anesthesia]. | The elderly show changes in various parenchymas linked to the process of ageing. Pathological abnormalities may be added to this picture leading to physiopathology peculiar to the aged. In relation to special problems raised by this background, the advantages and disadvantages of N.L.A. are discussed. The authors refer... | [Place of neuroleptics in geriatric anesthesia]. The elderly show changes in various parenchymas linked to the process of ageing. Pathological abnormalities may be added to this picture leading to physiopathology peculiar to the aged. In relation to special problems raised by this background, the advantages and disadva... | [
-0.02896406129002571,
0.015396935865283012,
0.008073121309280396,
0.007093789521604776,
0.02412569150328636,
0.039376962929964066,
0.07334791868925095,
0.017518892884254456,
-0.037122879177331924,
-0.03630674630403519,
-0.025949791073799133,
0.07630171626806259,
-0.010180175304412842,
0.08... |
PMID:14567 | [Current place of neuroleptics in cardiac surgery under extracorporeal circulation. Cardiovascular effects of different combinations]. | We have been using narconeuroleptanalgesia for anesthesia in cardiac surgery under extra-corporeal circulation since 1969, and we have carried out about 3,500 anesthetics of this type on the 1st of October 1975. For all these anesthetics, the neuroleptic used was droperidol. The other components were: - in the case of ... | [Current place of neuroleptics in cardiac surgery under extracorporeal circulation. Cardiovascular effects of different combinations]. We have been using narconeuroleptanalgesia for anesthesia in cardiac surgery under extra-corporeal circulation since 1969, and we have carried out about 3,500 anesthetics of this type o... | [
-0.02386830560863018,
-0.024015430361032486,
0.030127663165330887,
0.007623495068401098,
-0.01277543418109417,
0.01713029108941555,
0.03124959208071232,
0.05166669189929962,
0.019467348232865334,
-0.04026080295443535,
-0.02126498892903328,
0.03810857981443405,
-0.04163898527622223,
-0.0065... |
PMID:14569 | [Neuroplegia in cranial and cranio-thoracic injuries]. | During severe head injuries, the reaction to the cerebral lesion is intense and characterised by a disturbance which is automatic, vasomotor and endocrine. Associated with general ventilatory and nutritional resuscitation, neuroplegia occupies in this pathology, aplace of choice. Cranio-thoracic traumas raise more comp... | [Neuroplegia in cranial and cranio-thoracic injuries]. During severe head injuries, the reaction to the cerebral lesion is intense and characterised by a disturbance which is automatic, vasomotor and endocrine. Associated with general ventilatory and nutritional resuscitation, neuroplegia occupies in this pathology, ap... | [
-0.028955278918147087,
-0.002231362508609891,
-0.02618076093494892,
-0.005064202938228846,
-0.008247454650700092,
0.11242080479860306,
0.05421070009469986,
0.061003733426332474,
-0.04377486929297447,
-0.027843408286571503,
-0.017588844522833824,
-0.007626992184668779,
-0.058225542306900024,
... |
PMID:14570 | [Place of neuroleptics in neurosurgical anesthesia-resuscitation]. | The interest of neuroleptics in neurosurgery should be examined in the light of physiopathological and pharmacological data concerning cerebral circulatory autoregulation and intracranial pressure. The fairly favourable conclusions permit one to consider their wide use justified, especially, by the feeble hypnogenic ef... | [Place of neuroleptics in neurosurgical anesthesia-resuscitation]. The interest of neuroleptics in neurosurgery should be examined in the light of physiopathological and pharmacological data concerning cerebral circulatory autoregulation and intracranial pressure. The fairly favourable conclusions permit one to conside... | [
0.000876629026606679,
0.029973801225423813,
0.00398945901542902,
0.007805717643350363,
-0.01381331030279398,
0.09086256474256516,
0.11817839741706848,
0.046695832163095474,
-0.04292645677924156,
-0.04495151340961456,
-0.04684979096055031,
0.019230475649237633,
-0.02475719526410103,
0.05934... |
PMID:14571 | [Very-high-dose droperidol and brain stem injuries]. | Treating four comatose children with severe injuries of the brain stem, suffering from severe autonomic disorders without any indications for neurosurgery, we were led to increase gradually the doses of neuroleptics used as basis of treatment, the main one being Droperidol. The increase in dosage, often reaching very h... | [Very-high-dose droperidol and brain stem injuries]. Treating four comatose children with severe injuries of the brain stem, suffering from severe autonomic disorders without any indications for neurosurgery, we were led to increase gradually the doses of neuroleptics used as basis of treatment, the main one being Drop... | [
-0.04734739288687706,
0.012755639851093292,
0.017747977748513222,
-0.031240329146385193,
-0.009287548251450062,
0.015453668311238289,
0.036468058824539185,
0.043926265090703964,
-0.022741803899407387,
-0.06773011386394501,
0.06839286535978317,
0.015871291980147362,
-0.014181872829794884,
0... |
PMID:14572 | [Neuroleptics and continuous measurement of intracranial pressure]. | Neurosurgical patients, whether injured or not, have benefited in recent years from a new technique of supervision, measurement of thr intracranial pressure (ICP). Thus, measurement of a pressure figure and its course, gives precious information, both diagnostic and therapeutic. Various techniques of measurement are no... | [Neuroleptics and continuous measurement of intracranial pressure]. Neurosurgical patients, whether injured or not, have benefited in recent years from a new technique of supervision, measurement of thr intracranial pressure (ICP). Thus, measurement of a pressure figure and its course, gives precious information, both ... | [
-0.05090178921818733,
0.01697477325797081,
0.04310869798064232,
-0.04051384702324867,
-0.02210923098027706,
0.07361526042222977,
0.1143111139535904,
0.0234353207051754,
0.005190885625779629,
-0.04010557755827904,
-0.0011411627056077123,
-0.04569918289780617,
-0.026500001549720764,
0.035365... |
PMID:14573 | [Note on the comparative effects of benzodiazepines and chlorpromazine on intracranial pressure in the dog]. | The neutrality of the butyrophenones on intracranial pressure has been relatively well shown. That of the phenothiazines and benzodiazepine derivatives has been less well established. The authors studied, by a continuous method, the action of chlorpromazine, acepromazine and three benzodiazepines (diazepam, flunitrazep... | [Note on the comparative effects of benzodiazepines and chlorpromazine on intracranial pressure in the dog]. The neutrality of the butyrophenones on intracranial pressure has been relatively well shown. That of the phenothiazines and benzodiazepine derivatives has been less well established. The authors studied, by a c... | [
-0.07366327196359634,
-0.011374412104487419,
-0.004881585948169231,
0.03899189457297325,
-0.013582166284322739,
0.059020671993494034,
0.06175694242119789,
0.03857872262597084,
-0.010242171585559845,
-0.04854033887386322,
-0.04597710818052292,
-0.012027900665998459,
0.004055347293615341,
0.... |
PMID:14575 | Effect of adrenalectomy in the dog on blood gas tensions and oxygen content. | Arterial and venous blood gas tensions and pH were determined in 8 dogs during a control interval, while adrenal deficient, and following replacement therapy with corticosteroids. Additionally, erythrocyte 2,3-diphosphoglycerate (DPG) values were measured, and oxygen tension (mm of Hg) when hemoglobin is half-saturated... | Effect of adrenalectomy in the dog on blood gas tensions and oxygen content. Arterial and venous blood gas tensions and pH were determined in 8 dogs during a control interval, while adrenal deficient, and following replacement therapy with corticosteroids. Additionally, erythrocyte 2,3-diphosphoglycerate (DPG) values w... | [
-0.054550882428884506,
-0.0030792481265962124,
0.055599797517061234,
0.048438552767038345,
0.002528878627344966,
-0.032145947217941284,
0.054447099566459656,
0.014435029588639736,
-0.07549786567687988,
-0.010892897844314575,
0.001019116141833365,
-0.052863847464323044,
-0.0006520856404677033... |
PMID:14576 | Salicylate pulmonary edema: the mechanism in sheep and review of the clinical literature. | Several clinical reports of salicylate-induced pulmonary edema led us to investigate the mechanism in a chronic unanesthetized sheep preparation. We infused an aspirin-buffer solution intravenously at rates up to 1,200 mg of aspirin per hour and compared effects on lung lymph flow and lymph protein concentration to tho... | Salicylate pulmonary edema: the mechanism in sheep and review of the clinical literature. Several clinical reports of salicylate-induced pulmonary edema led us to investigate the mechanism in a chronic unanesthetized sheep preparation. We infused an aspirin-buffer solution intravenously at rates up to 1,200 mg of aspir... | [
-0.10636758804321289,
-0.03133158013224602,
-0.0496501587331295,
0.025391247123479843,
0.04303155466914177,
-0.014290626160800457,
0.08337055891752243,
0.07473360002040863,
-0.032727278769016266,
-0.013534868136048317,
0.04974394664168358,
-0.03572233393788338,
0.004533623345196247,
0.0451... |
PMID:14577 | Treatment of brain disease with dietary precursors of neurotransmitters. | A growing number of brain diseases are characterized by decreased levels of one or more of the neurotransmitters. Recent experimental evidence indicates that nutritional factors strongly influence the regulation of two of these neurotransmitters, serotonin and acetylcholine. As a result, attempts are now being made to ... | Treatment of brain disease with dietary precursors of neurotransmitters. A growing number of brain diseases are characterized by decreased levels of one or more of the neurotransmitters. Recent experimental evidence indicates that nutritional factors strongly influence the regulation of two of these neurotransmitters, ... | [
-0.023693552240729332,
0.007468073163181543,
0.004375542979687452,
-0.005045935045927763,
-0.05696486309170723,
0.03232046961784363,
0.07923481613397598,
0.014820189215242863,
-0.0017623420571908355,
-0.05897459387779236,
-0.009192091412842274,
-0.07108745723962784,
0.019916396588087082,
0... |
PMID:14578 | [Rabies glycoprotein purification by isoelectric focusing (author's transl)]. | A glycoprotein was extracted with Triton X100 from rabies virus grown in primary foetal bovine kidney cells. This glycoprotein was further purified by iso electro focusing and showed a major peak at pH 7,0 and a smaller peak at pH 4,6. Purified fractions were migrated on polyacrylamide gels and assayed for immunogenici... | [Rabies glycoprotein purification by isoelectric focusing (author's transl)]. A glycoprotein was extracted with Triton X100 from rabies virus grown in primary foetal bovine kidney cells. This glycoprotein was further purified by iso electro focusing and showed a major peak at pH 7,0 and a smaller peak at pH 4,6. Purifi... | [
-0.03248871862888336,
-0.01356839295476675,
-0.03528134897351265,
-0.02135622501373291,
0.016746677458286285,
-0.07020898908376694,
0.06824711710214615,
0.06100044026970863,
-0.05403004586696625,
0.010271439328789711,
0.011706280522048473,
-0.1166456863284111,
0.028340749442577362,
0.02240... |
PMID:14579 | [Studies on the mechanism of interaction of glutaraldehyde with microorganisms (author's transl)]. | The antimicrobial action of glutaraldehyde on Candida lipolytica increases with reagent concentration, pH and duration of contact. The simultaneous study of the size distribution of the particles shows an agglutination of the cells. This result is confirmed by direct observation of the cells by electron microscopy. Cel... | [Studies on the mechanism of interaction of glutaraldehyde with microorganisms (author's transl)]. The antimicrobial action of glutaraldehyde on Candida lipolytica increases with reagent concentration, pH and duration of contact. The simultaneous study of the size distribution of the particles shows an agglutination of... | [
0.022410662844777107,
0.007995623163878918,
-0.009663802571594715,
0.023295892402529716,
0.00012322512338869274,
-0.10262320190668106,
0.04900379851460457,
0.008969628252089024,
-0.02803458273410797,
0.01931673102080822,
-0.010619607754051685,
-0.02921241894364357,
0.02749478816986084,
0.0... |
PMID:14586 | [Familial palmo-plantar keratoderma with epidermolytic hyperkeratosis (author's transl)]. | Three cases of palmo-plantar keratoderma coming from three different families are reported; Clinical features were those of Thost-Unna's disease; histo-pathological and ultrastructural aspects resembled those of the epidermolytic hyperkeratosis. The literature, 13 cases within 7 families with the same clinical and hist... | [Familial palmo-plantar keratoderma with epidermolytic hyperkeratosis (author's transl)]. Three cases of palmo-plantar keratoderma coming from three different families are reported; Clinical features were those of Thost-Unna's disease; histo-pathological and ultrastructural aspects resembled those of the epidermolytic ... | [
0.04236701503396034,
0.0142403244972229,
0.02707117795944214,
0.061952900141477585,
0.004789167549461126,
-0.024131296202540398,
0.03675099462270737,
0.021013032644987106,
-0.0627240315079689,
-0.03636615723371506,
0.011586793698370457,
-0.15421347320079803,
0.0029386680107563734,
-0.01170... |
PMID:14588 | Comparison of thiopentone versus althesin for caesarean section. | Thiopentone and Althesin were compared in 50 patients undergoing general anaesthesia for Caesarean section. The patients were divided into group A (24 mothers) were thiopentone (3.5 mg/kg) was used for induction and group B (26 mothers) where Althesin (80 mu1/kg) was employed. Blood samples for estimating the maternal ... | Comparison of thiopentone versus althesin for caesarean section. Thiopentone and Althesin were compared in 50 patients undergoing general anaesthesia for Caesarean section. The patients were divided into group A (24 mothers) were thiopentone (3.5 mg/kg) was used for induction and group B (26 mothers) where Althesin (80... | [
-0.0675397664308548,
0.006164481397718191,
-0.024098142981529236,
0.018511297181248665,
-0.03681211546063423,
0.0415690615773201,
0.04193546250462532,
0.04316543787717819,
-0.019777128472924232,
-0.005620607174932957,
-0.039608780294656754,
-0.0229368656873703,
-0.01998661272227764,
0.0366... |
PMID:14589 | [Optimization of conditions for determining the activity of amphotericin B]. | The effect of incubation temperature, pH and medium composition on the size of the growth inhibitions zones, clearance of their borders and slope of the dose-response curve in determin ation of the biological activity of amphotericin B by the agar-diffusion method using Candida scotti, Tul-1 as the test-microbe was st... | [Optimization of conditions for determining the activity of amphotericin B]. The effect of incubation temperature, pH and medium composition on the size of the growth inhibitions zones, clearance of their borders and slope of the dose-response curve in determin ation of the biological activity of amphotericin B by the... | [
-0.024612421169877052,
0.0050454349257051945,
-0.0032379585318267345,
-0.016191326081752777,
0.043144043534994125,
0.020362360402941704,
-0.0031852442771196365,
0.0691392719745636,
-0.060399509966373444,
-0.028722921386361122,
0.013081984594464302,
-0.04515403136610985,
0.026765692979097366,... |
PMID:14600 | The phenol oxidases of the ascomycete Podospora anserina. XII. Affinity of laccases II and III to substrates with different substitution patterns. | For the low molecular weight laccases II and III of Podospora anserina the kinetic parameters Michaelis constant (KM) and maximum reaction velocity (V) were determined polarographically under pH optimum conditions for representative substrates of different substitution patterns. Laccase II showed two peaks in its pH op... | The phenol oxidases of the ascomycete Podospora anserina. XII. Affinity of laccases II and III to substrates with different substitution patterns. For the low molecular weight laccases II and III of Podospora anserina the kinetic parameters Michaelis constant (KM) and maximum reaction velocity (V) were determined polar... | [
-0.05798068642616272,
-0.009482505731284618,
-0.031222650781273842,
0.031407322734594345,
0.07836876064538956,
-0.08016052842140198,
0.01293496135622263,
0.007765427231788635,
-0.0323113352060318,
0.035316064953804016,
0.016924861818552017,
-0.05959365889430046,
-0.01954733580350876,
-0.01... |
PMID:14601 | Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and Lactobacillus curvatus. | The stability, pH-dependence and kinetic properties of the Mn2+ and FDP-activated NAD-dependent lactic acid dehydrogenases from Lactobacillus casei ssp. casei (ATCC 393) and L. curvatus (DSM 20010) were studied after the enzymes were purified to homogeneity by affinity chromatography. Both enzymes are virtually unidire... | Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and Lactobacillus curvatus. The stability, pH-dependence and kinetic properties of the Mn2+ and FDP-activated NAD-dependent lactic aci... | [
-0.07214291393756866,
-0.022764137014746666,
-0.04486386105418205,
0.03845616802573204,
0.0391199067234993,
-0.04415229335427284,
0.017440609633922577,
0.07712884247303009,
-0.05164576321840286,
-0.050302185118198395,
0.05395359918475151,
-0.046954747289419174,
0.03388677164912224,
-0.0496... |
PMID:14602 | Therapeutic usefulness of propoxyphene napsylate in narcotic addiction. | The maximum doses of propoxyphene napsylate used to treat heroin addicts produce a degree of morphine-like activity equal to that produced by 20 to 25 mg/day of subcutaneously given morphine or 10 mg/day orally given methadone. This degree of activity wound be sufficient to ameliorate abstinence even in patients depend... | Therapeutic usefulness of propoxyphene napsylate in narcotic addiction. The maximum doses of propoxyphene napsylate used to treat heroin addicts produce a degree of morphine-like activity equal to that produced by 20 to 25 mg/day of subcutaneously given morphine or 10 mg/day orally given methadone. This degree of activ... | [
-0.03286202251911163,
0.020152229815721512,
-0.027538811787962914,
-0.02365201897919178,
-0.01924283802509308,
0.01726091466844082,
0.028363507241010666,
0.04527562856674194,
-0.02026747725903988,
-0.007982522249221802,
0.022038089111447334,
0.0016127927228808403,
0.04207802936434746,
0.03... |
PMID:14603 | Antidepressants and the muscarinic acetylcholine receptor. | Several tricyclic antidepressants have been assessed for their potency in binding to the muscarinic acetylcholine receptor of brain and intestine. Amitriptyline hydrochloride is about ten times as potent as imipramine hydrochloride. Dimethylated drugs are more potent than monomethylated ones. The relative anticholinerg... | Antidepressants and the muscarinic acetylcholine receptor. Several tricyclic antidepressants have been assessed for their potency in binding to the muscarinic acetylcholine receptor of brain and intestine. Amitriptyline hydrochloride is about ten times as potent as imipramine hydrochloride. Dimethylated drugs are more ... | [
-0.042223941534757614,
-0.022169997915625572,
-0.026756778359413147,
0.015566857531666756,
-0.05920083820819855,
-0.01099441759288311,
0.018209075555205345,
0.03293913975358009,
-0.006704601459205151,
-0.05978894978761673,
-0.014377312734723091,
-0.031302355229854584,
0.031262025237083435,
... |
PMID:14599 | [Acute sepsis caused by "Gaffkya tetragena" in adult with hypogammaglobulinemia (author's transl)]. | A case of acute sepsis caused by Gaffkya tetragena in an adult with acquired hypogammaglobulinemia has been described. The Authors pointout the importance that particular conditions of disreactivity and/or of immunodeficiency can play in the acquistion of pathogenicity by Gaffkya tetragena. In the case under discussion... | [Acute sepsis caused by "Gaffkya tetragena" in adult with hypogammaglobulinemia (author's transl)]. A case of acute sepsis caused by Gaffkya tetragena in an adult with acquired hypogammaglobulinemia has been described. The Authors pointout the importance that particular conditions of disreactivity and/or of immunodefic... | [
-0.010089969262480736,
-0.017483042553067207,
-0.012133765034377575,
0.009960467927157879,
0.012544861994683743,
-0.04777141660451889,
0.11172587424516678,
0.07361967116594315,
-0.0957038402557373,
-0.02098095789551735,
-0.08186328411102295,
-0.05272418633103371,
0.01611372083425522,
0.019... |
PMID:14606 | [Clinical trial with barbexaclone in epilepsies]. | A open clinic assay with barbexaclone which is an association of phenobarvital with light stimulant of the central nervous system (tau-l-ciclohexil-2-methil-aminopropane) for the treatment of epileptic disorders is reported. The authors have studied 40 patients aged between 0-12 years of age, of both sexes, all of them... | [Clinical trial with barbexaclone in epilepsies]. A open clinic assay with barbexaclone which is an association of phenobarvital with light stimulant of the central nervous system (tau-l-ciclohexil-2-methil-aminopropane) for the treatment of epileptic disorders is reported. The authors have studied 40 patients aged bet... | [
-0.06470907479524612,
0.036113619804382324,
-0.008587286807596684,
0.03073129989206791,
-0.0021822028793394566,
0.0028269514441490173,
0.0036597605794668198,
0.035807449370622635,
-0.0027790775056928396,
-0.027230829000473022,
0.025711379945278168,
-0.05806145817041397,
0.019283758476376534,... |
PMID:14607 | Simultaneous determination of skeletal muscle fiber, types I, IIA, and IIB by histochemistry. | We describe a simplified technique for the histochemical determination of three fiber types from a single section of skeletal muscle. Preincubation in a solution of formaldehyde, glycine, and calcium followed by routine myofibrillar adenosine triphosphatase (ATPase) incubation clearly differentiates type I, type IIA, a... | Simultaneous determination of skeletal muscle fiber, types I, IIA, and IIB by histochemistry. We describe a simplified technique for the histochemical determination of three fiber types from a single section of skeletal muscle. Preincubation in a solution of formaldehyde, glycine, and calcium followed by routine myofib... | [
-0.04359214007854462,
-0.02664666436612606,
0.012179176323115826,
-0.0009827387984842062,
0.02535562962293625,
-0.04072290286421776,
0.032395996153354645,
-0.018932266160845757,
-0.010262777097523212,
-0.029672494158148766,
0.03289158269762993,
-0.07520431280136108,
-0.03067866899073124,
0... |
PMID:14608 | Variations in the spectrum of desulfoviridin from Desulfovibrio gigas. | Desulfoviridin preparations from D. gigas showed variations in the position of the absorption maximum the beta-peak) in the 580-nm region of the specturm. On treatment with Na2S2O4 a preparation with a beta-peak at 585 nm was affected rapidly, the 585-nm peak shifting to the 596-nm region; this was partially reversed b... | Variations in the spectrum of desulfoviridin from Desulfovibrio gigas. Desulfoviridin preparations from D. gigas showed variations in the position of the absorption maximum the beta-peak) in the 580-nm region of the specturm. On treatment with Na2S2O4 a preparation with a beta-peak at 585 nm was affected rapidly, the 5... | [
-0.06963479518890381,
-0.0233654472976923,
0.029581381008028984,
0.0009318428346887231,
0.05029232054948807,
0.035977691411972046,
0.03167615458369255,
0.014440744183957577,
-0.05420437455177307,
0.013087955303490162,
0.054303526878356934,
-0.05066508427262306,
0.009892929345369339,
0.0202... |
PMID:14609 | An alternative coupling procedure for preparing activated sepharose for affinity chromatography of penicillinase. | Most applications of affinity chromatography employ the cyanogen bromide activation scheme first devised by Axèn et al. (1967). Porath and Sunberg (1972) reported an alternative procedure in which phloroglucinol and divinylsulphone are used in activating reactions. The advantages of this scheme and parameters relevant ... | An alternative coupling procedure for preparing activated sepharose for affinity chromatography of penicillinase. Most applications of affinity chromatography employ the cyanogen bromide activation scheme first devised by Axèn et al. (1967). Porath and Sunberg (1972) reported an alternative procedure in which phloroglu... | [
-0.10317441076040268,
-0.021906476467847824,
-0.06114030256867409,
-0.03766226768493652,
0.016447432339191437,
0.005205257795751095,
0.049709126353263855,
0.05739201232790947,
-0.05827992781996727,
-0.009190976619720459,
-0.008125649765133858,
-0.04293813183903694,
-0.014095809310674667,
0... |
PMID:14610 | Studies on the apoproteins of the major lipoprotein of the yolk of hen's eggs II. The dimer-tetramer transition of apovitellenin I. | Further studies have been made of the physical properties of hen's apovitellenin I, the principal low-molecular-weight protein from the high-lipid low density lipoprotein of the yolk of hen's eggs. The methods used included chromatography, sedimentation, viscosity, optical rotation, and spin labelling; the solvents use... | Studies on the apoproteins of the major lipoprotein of the yolk of hen's eggs II. The dimer-tetramer transition of apovitellenin I. Further studies have been made of the physical properties of hen's apovitellenin I, the principal low-molecular-weight protein from the high-lipid low density lipoprotein of the yolk of he... | [
-0.09703774750232697,
-0.029321137815713882,
-0.03236014395952225,
-0.006126378662884235,
-0.027649879455566406,
0.040033239871263504,
0.05966993421316147,
0.02594873495399952,
-0.019704818725585938,
-0.04375430941581726,
-0.016980484127998352,
-0.09922169148921967,
0.0007108488935045898,
... |
PMID:14611 | Biochemical differences between alcohol dehydrogenases of Drosophila melanogaster. | This paper describes substrate specificities, developmental changes in activity, pH profiles, and heat stabilities of isozymes produced by four Adh genotypes in D. melanogaster. No differences are found in the substrate specificities of isozymes from the different genotypes but studies of the other three properties rev... | Biochemical differences between alcohol dehydrogenases of Drosophila melanogaster. This paper describes substrate specificities, developmental changes in activity, pH profiles, and heat stabilities of isozymes produced by four Adh genotypes in D. melanogaster. No differences are found in the substrate specificities of ... | [
0.020245634019374847,
-0.012686695903539658,
-0.0278780534863472,
0.02951114997267723,
0.060877472162246704,
-0.007268157787621021,
0.011699074879288673,
0.05521159619092941,
-0.08667728304862976,
-0.07102267444133759,
0.036275070160627365,
-0.05086584389209747,
-0.03323594108223915,
0.019... |
PMID:14612 | Ord River arboviruses--the study site and mosquitoes. | The Ord Valey of tropical Western Australia has been studied for arbovirus activity following the development of a man-made lake of considerable size, a diversion dam and an irrigation scheme. Kununurra, the largest town in the valley, is the focus for very large populations of birds and mosquitoes. The irrigation are... | Ord River arboviruses--the study site and mosquitoes. The Ord Valey of tropical Western Australia has been studied for arbovirus activity following the development of a man-made lake of considerable size, a diversion dam and an irrigation scheme. Kununurra, the largest town in the valley, is the focus for very large po... | [
0.01624801941215992,
-0.03357556089758873,
-0.02684551291167736,
0.02613712288439274,
0.08640410006046295,
-0.018513696268200874,
0.04983607307076454,
0.0664038136601448,
-0.07957501709461212,
0.023685893043875694,
0.03275243937969208,
-0.10272382944822311,
0.018320150673389435,
-0.0287286... |
PMID:14613 | Ord River arboviruses--isolations from mosquitoes. | One hundred and thirty presumptive viruses have been isolated from 485 pools made from 23,872 mosquitoes collected in the Ord River area of North-West Australia. One hundred and eleven of the virus isolates isolates came from pools of Culex annulirostis, the dominant mosquito species caught in the vicinity of Kununurra... | Ord River arboviruses--isolations from mosquitoes. One hundred and thirty presumptive viruses have been isolated from 485 pools made from 23,872 mosquitoes collected in the Ord River area of North-West Australia. One hundred and eleven of the virus isolates isolates came from pools of Culex annulirostis, the dominant m... | [
-0.004713929258286953,
-0.035614918917417526,
-0.042001038789749146,
0.013665935024619102,
0.06479497998952866,
-0.027965392917394638,
0.06636583805084229,
0.02044771984219551,
-0.027441902086138725,
0.019562339410185814,
0.017573298886418343,
-0.08584169298410416,
-0.018384592607617378,
-... |
PMID:14614 | Essential hypertension--the starting point for improved drug treatment. | Hypertension is a common disease and plays an important role as a potentially remediable contributor to cardiovascular causes of death in the community. In moderate to severe hypertension recent treatment has improved morbidity and mortality substantially, but it is disappointing that despite this myocardial infarction... | Essential hypertension--the starting point for improved drug treatment. Hypertension is a common disease and plays an important role as a potentially remediable contributor to cardiovascular causes of death in the community. In moderate to severe hypertension recent treatment has improved morbidity and mortality substa... | [
-0.012195971794426441,
-0.01361964549869299,
0.048364877700805664,
-0.011882389895617962,
0.00875054206699133,
-0.012819042429327965,
0.06842367351055145,
0.04152856767177582,
0.012099240906536579,
-0.07901928573846817,
0.03404107689857483,
-0.00012643207446672022,
0.0037198031786829233,
0... |
PMID:14616 | Pharmacodynamic studies on the antihypertensive effectiveness of beta-blocking drugs. | Beta-adrenoceptor antagonists are effective antihypertensive agents in the majority of patients with uncomplicated essential hypertension. Their antipressor activity is greater on systolic than diastolic pressure and greatest during dynamic exertion. Their circulatory effects are maximum within 1-2 hours of ingestion a... | Pharmacodynamic studies on the antihypertensive effectiveness of beta-blocking drugs. Beta-adrenoceptor antagonists are effective antihypertensive agents in the majority of patients with uncomplicated essential hypertension. Their antipressor activity is greater on systolic than diastolic pressure and greatest during d... | [
-0.04563482850790024,
0.01948404498398304,
0.03243035450577736,
0.03192398324608803,
-0.03296332433819771,
-0.014311247505247593,
0.03615548461675644,
0.040733013302087784,
-0.055165845900774,
-0.07432950288057327,
-0.020539546385407448,
0.014867821708321571,
-0.024909915402531624,
0.03633... |
PMID:14617 | Blood pressure variability in patients on beta-blockers. | The direct arterial blood pressure was monitored over 24 hours in unrestricted untreated patients in order to obtain the average pressure and standard deviation over 24 hours. The standard deviation was taken as the index of variability of pressure. In eight subjects the study was repeated three months after commenceme... | Blood pressure variability in patients on beta-blockers. The direct arterial blood pressure was monitored over 24 hours in unrestricted untreated patients in order to obtain the average pressure and standard deviation over 24 hours. The standard deviation was taken as the index of variability of pressure. In eight subj... | [
-0.03834884986281395,
0.009884292259812355,
0.007731955032795668,
0.06288915127515793,
-0.016945624724030495,
0.001660138019360602,
0.0513741672039032,
-0.013113615103065968,
0.002456407528370619,
-0.06862916052341461,
-0.02075997181236744,
0.009880381636321545,
0.03269297629594803,
0.0460... |
PMID:14622 | A beta-blocker-based antihypertensive drug program guided by age and renin. | From analyses of the effectiveness of beta-blocker monotherapy in relation to the patient's age and to pre-treatment renin determinations an antihypertensive drug program is proposed in which beta-blockers form the cornerstone. Patients with essential hypertension can be subdivided into groups with low (19%), normal (5... | A beta-blocker-based antihypertensive drug program guided by age and renin. From analyses of the effectiveness of beta-blocker monotherapy in relation to the patient's age and to pre-treatment renin determinations an antihypertensive drug program is proposed in which beta-blockers form the cornerstone. Patients with es... | [
-0.05271046236157417,
0.009199300780892372,
-0.006291576661169529,
0.004241520538926125,
-0.014241418801248074,
-0.009709062054753304,
0.02178931050002575,
0.009104089811444283,
-0.02272098883986473,
-0.06791047751903534,
-0.0014114509103819728,
0.015971936285495758,
0.018210913985967636,
... |
PMID:14623 | The pharmacokinetic characteristics of beta-receptor antagonists in man--similarities and differences of clinical relevance. | The aliphatic partial structure common to the beta-receptor antagonists leads to similar products of their biotransformation. The main qualitative and quantitative differences of the metabolism of the compounds of this class, however, rest in the nature of their aromatic or heterocyclic substituents. The physico-chemic... | The pharmacokinetic characteristics of beta-receptor antagonists in man--similarities and differences of clinical relevance. The aliphatic partial structure common to the beta-receptor antagonists leads to similar products of their biotransformation. The main qualitative and quantitative differences of the metabolism o... | [
-0.05746264010667801,
0.004149044398218393,
-0.036818668246269226,
-0.007305577397346497,
0.017640870064496994,
-0.017173880711197853,
0.03599563613533974,
0.002897979225963354,
-0.0026214609388262033,
-0.07461061328649521,
-0.013873935677111149,
-0.050249673426151276,
-0.0033381502144038677... |
PMID:14625 | The vasodilator--beta-blocker interaction--some determinants of its clinical success. | A number of structurally dissimilar compounds, sharing the ability to induce vasodilatation have come into clinical usefulness as antihypertensive drugs. Their successful utilisation often depends critically on an appropriate combination with diuretics and beta-blockers. Beta-blockers can specifically inhibit the refle... | The vasodilator--beta-blocker interaction--some determinants of its clinical success. A number of structurally dissimilar compounds, sharing the ability to induce vasodilatation have come into clinical usefulness as antihypertensive drugs. Their successful utilisation often depends critically on an appropriate combinat... | [
-0.057344868779182434,
0.059787604957818985,
-0.013618972152471542,
0.031952206045389175,
-0.032760314643383026,
-0.027089694514870644,
0.034596096724271774,
0.01976115256547928,
-0.005074897315353155,
-0.07639333605766296,
-0.0026283913757652044,
0.0011555561795830727,
0.031905241310596466,... |
PMID:14626 | Additive effect of beta-adrenergic blockers in combination with vasodilators in lowering blood pressure. | Complications of hypertension are by far the greatese preventable public health problem in many of the developed countries of the world. Pharmacologic interventions which primarily involve drug interactions are the generally available and effective means of preventing or delaying these hypertensive complications. Mecha... | Additive effect of beta-adrenergic blockers in combination with vasodilators in lowering blood pressure. Complications of hypertension are by far the greatese preventable public health problem in many of the developed countries of the world. Pharmacologic interventions which primarily involve drug interactions are the ... | [
-0.06875254958868027,
0.014808645471930504,
0.005589934065937996,
0.05994700267910957,
-0.02957824058830738,
-0.060003701597452164,
0.04364717751741409,
0.04804876819252968,
-0.06209215521812439,
-0.06264983117580414,
-0.011971460655331612,
0.027150459587574005,
0.05137057974934578,
0.0402... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.