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PMID:15314 | Continuous oesophageal pH recording and acid-clearing test. A study of reproducibility. | Ten investigations of acid reflux by means of 12-hour continuous pH monitoring at the distal end of the oesophagus, and 10 acid-clearing tests were performed within 6 weeks on the same volunteer with the purpose of examining the reproducibility of the results of these tests. Intragastric pH was studied over 12 hours an... | Continuous oesophageal pH recording and acid-clearing test. A study of reproducibility. Ten investigations of acid reflux by means of 12-hour continuous pH monitoring at the distal end of the oesophagus, and 10 acid-clearing tests were performed within 6 weeks on the same volunteer with the purpose of examining the rep... | [
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PMID:15315 | Theta-bearing cells in the bone marrow of thymus-deprived mice. Numbers and nature. | Theta-bearing cells in lymphomyeloid tissues of thymus-deprived and normal mice have been studied by the use of anti-theta antiserum and cytotoxicity tests in addition to functional tests. In contrast to the findings in peripheral lymphoid tissues, increased percentages and numbers of theta-bearing cells were found in ... | Theta-bearing cells in the bone marrow of thymus-deprived mice. Numbers and nature. Theta-bearing cells in lymphomyeloid tissues of thymus-deprived and normal mice have been studied by the use of anti-theta antiserum and cytotoxicity tests in addition to functional tests. In contrast to the findings in peripheral lymph... | [
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PMID:15317 | Tris buffer attenuates acetylcholine responses in Aplysia neurons. | The commonly used buffering agent tris(hydroxymethyl)methylamine (tris) antagonizes the action of iontophoretically applied acetylcholine on neurons of Aplysia californica. Concentrations of 5 to 10 millimolar tris markedly reduced both excitatory and inhibitory responses. | Tris buffer attenuates acetylcholine responses in Aplysia neurons. The commonly used buffering agent tris(hydroxymethyl)methylamine (tris) antagonizes the action of iontophoretically applied acetylcholine on neurons of Aplysia californica. Concentrations of 5 to 10 millimolar tris markedly reduced both excitatory and i... | [
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PMID:15320 | Injuries from sea urchins. | Injuries from sea urchins result from penetration of the calcareous spines into the skin. Local pain of several days' duration is the most common symptom, but systemic reaction from toxins found in certain species can occur. There is no uniformly accepted successful treatment other than cleansing the wound. Attempts to... | Injuries from sea urchins. Injuries from sea urchins result from penetration of the calcareous spines into the skin. Local pain of several days' duration is the most common symptom, but systemic reaction from toxins found in certain species can occur. There is no uniformly accepted successful treatment other than clean... | [
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PMID:15322 | The effect of a sodium citrate preparation compared with an aluminium-magnesium hydroxide preparation on the urinary pH of normal subjects. | The effects of a sodium citrate preparation in two dosage regimens (4 g 4 times daily and 8 g 4 times daily) and of an aluminium-magnesium hydroxide suspension (15 ml 4 times daily) on the urinary pH of 19 healthy subjects were compared. The sodium citrate preparation in both dosages proved to be superior to the alumin... | The effect of a sodium citrate preparation compared with an aluminium-magnesium hydroxide preparation on the urinary pH of normal subjects. The effects of a sodium citrate preparation in two dosage regimens (4 g 4 times daily and 8 g 4 times daily) and of an aluminium-magnesium hydroxide suspension (15 ml 4 times daily... | [
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PMID:15323 | Medical treatment of hypertension. | The management of hypertension with current hypotensive drugs on the South African pharmaceutical market is reviewed. The advent of the use of beta-adrenergic blocking agents and vasodilators in the treatment of hypertension is promising. | Medical treatment of hypertension. The management of hypertension with current hypotensive drugs on the South African pharmaceutical market is reviewed. The advent of the use of beta-adrenergic blocking agents and vasodilators in the treatment of hypertension is promising. | [
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PMID:15319 | [Endocrine polyadenomatosis with carcinoid tumor]. | The authors review 26 cases of multiple endocrine tumours with presence of a carcinoid tumour. In 44% the carcinoid was localised to the bronchus, in 20% of cases to the small intestine or duodenum. In 76% of cases during multiple endocrine tumours, the carcinoid appeared in embryological derivatives of the anterior pa... | [Endocrine polyadenomatosis with carcinoid tumor]. The authors review 26 cases of multiple endocrine tumours with presence of a carcinoid tumour. In 44% the carcinoid was localised to the bronchus, in 20% of cases to the small intestine or duodenum. In 76% of cases during multiple endocrine tumours, the carcinoid appea... | [
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PMID:15324 | Clothiapine in the management of schizophrenia. | Forty Black men diagnosed as schizophrenic and admitted to Ingutsheni Hospital during a period of 3 months, were allocated alternately to treatment with either clothiapine or chlorpromazine. Six patients were excluded from the trial because of an incorrect diagnosis and 34, 17 in each group, completed the trial. The 2 ... | Clothiapine in the management of schizophrenia. Forty Black men diagnosed as schizophrenic and admitted to Ingutsheni Hospital during a period of 3 months, were allocated alternately to treatment with either clothiapine or chlorpromazine. Six patients were excluded from the trial because of an incorrect diagnosis and 3... | [
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PMID:15325 | Interpretation of alveolar-arterial oxygen tension difference. | In this study, an assessment is given of errors resulting from the use of the alveolar-arterial oxygen difference determined on both room air and 100% oxygen in estimating changes in total shunt fraction of 41 patients hospitalized with long bone fractures. In 113 studies, changes in alveolar-arterial oxygen difference... | Interpretation of alveolar-arterial oxygen tension difference. In this study, an assessment is given of errors resulting from the use of the alveolar-arterial oxygen difference determined on both room air and 100% oxygen in estimating changes in total shunt fraction of 41 patients hospitalized with long bone fractures.... | [
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PMID:15326 | The effect of furosemide on the flow and composition of bile in the dog. | The effect of furosemide, a potent inhibitor of active sodium transport, on the amount and composition of bile was studied in the dog. Ten milligrams per kilogram of body weight of furosemide were injected intravenously to anesthetized dogs with a previously constructed fistula of the common bile duct. In all dogs, a 2... | The effect of furosemide on the flow and composition of bile in the dog. The effect of furosemide, a potent inhibitor of active sodium transport, on the amount and composition of bile was studied in the dog. Ten milligrams per kilogram of body weight of furosemide were injected intravenously to anesthetized dogs with a... | [
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PMID:15327 | Effect of intraduodenal acid on the pre- and postvagotomy basal gastric secretion and gastrin. | Acid instillation into the duodenum inhibits basal and stimulated gastric secretion. In man vagotomy suppresses this secretory inhibition. It is postulated that such inhibition responds to a dual mechanism: an hormonal one (enterogastrone) and a nervous one (vagus nerve). This study showed that preoperative duodenal ac... | Effect of intraduodenal acid on the pre- and postvagotomy basal gastric secretion and gastrin. Acid instillation into the duodenum inhibits basal and stimulated gastric secretion. In man vagotomy suppresses this secretory inhibition. It is postulated that such inhibition responds to a dual mechanism: an hormonal one (e... | [
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PMID:15328 | Relationship between the prolongation of warm ischemia and the maximum available preservation period. | Fifty dog kidneys had hypothermic perfusion for 12 to 72 hours and then were transplanted. Prior to perfusion the kidneys were subjected to 15, 30, 45, and 60 minutes of warm ischemia. Fifteen minutes of warm ischemia was well tolerated (successful 72 hour preservation), but after 30 minutes successful preservation cou... | Relationship between the prolongation of warm ischemia and the maximum available preservation period. Fifty dog kidneys had hypothermic perfusion for 12 to 72 hours and then were transplanted. Prior to perfusion the kidneys were subjected to 15, 30, 45, and 60 minutes of warm ischemia. Fifteen minutes of warm ischemia ... | [
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PMID:15329 | Effect of endotoxin shock on skeletal muscle cell membrane potential. | Transmembrane potential changes were monitored in 21 dogs that were shocked by intravenous injectin of Difco purified endotoxin (055:B5). Corresponding serial measurements of electrolyte concentration in plasma and muscle biopsies were obtained to assess fluid and electrolyte changes. During shock the transmembrane pot... | Effect of endotoxin shock on skeletal muscle cell membrane potential. Transmembrane potential changes were monitored in 21 dogs that were shocked by intravenous injectin of Difco purified endotoxin (055:B5). Corresponding serial measurements of electrolyte concentration in plasma and muscle biopsies were obtained to as... | [
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PMID:15337 | [Effect of thymus cells on the radiosensitivity and differentiation trends of hematopoietic stem cells]. | A stimulating influence of thymus cells on the capability of irradiated (from 100 to 500 r) bone marrow of mice of producing colonies in spleen of syngenous recipient has been proven. The intensification of colony formation involves an increased radioresistance of stem cells. It is supposed that radioresistant thymus c... | [Effect of thymus cells on the radiosensitivity and differentiation trends of hematopoietic stem cells]. A stimulating influence of thymus cells on the capability of irradiated (from 100 to 500 r) bone marrow of mice of producing colonies in spleen of syngenous recipient has been proven. The intensification of colony f... | [
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PMID:15334 | Local mechanism of CO2 action of cat pial arterioles. | The effect of local hypercapnic acidosis or local hypocapnic alkalosis on pial arterioles were studied in anesthetized cats equipped with a cranial window for the direct observation of the pial microcirculation of the parietal cortex. Changes in PCO2 and pH of the extracellular fluid were induced by perfusing the space... | Local mechanism of CO2 action of cat pial arterioles. The effect of local hypercapnic acidosis or local hypocapnic alkalosis on pial arterioles were studied in anesthetized cats equipped with a cranial window for the direct observation of the pial microcirculation of the parietal cortex. Changes in PCO2 and pH of the e... | [
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PMID:15335 | Subclavian steal in Takayasu's arteritis. A hemodynamic study by means of ultrasonic Doppler flowmetry. | Blood flow in the vertebral artery and the upper extremity was studied in five cases of Takayasu's arteritis with subclavian steal by use of ultrasonic Doppler flowmetry and finger plethysmography. The diagnosis of subclavian steal was made by observation of flow reversal in the vertebral artery on the subclavian steal... | Subclavian steal in Takayasu's arteritis. A hemodynamic study by means of ultrasonic Doppler flowmetry. Blood flow in the vertebral artery and the upper extremity was studied in five cases of Takayasu's arteritis with subclavian steal by use of ultrasonic Doppler flowmetry and finger plethysmography. The diagnosis of s... | [
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PMID:15336 | Changes in agglomeration of human red blood cells in liquid storage in CPD media. | A procedure which may distinguish between old and new CPD blood units in liquid state is described. It is based on the observation of increased tendency to reversible agglomeration in old erythrocytes in liquid preservation. Erythrocytes clump together when they are mixed with low ionic strength solutions in pH range o... | Changes in agglomeration of human red blood cells in liquid storage in CPD media. A procedure which may distinguish between old and new CPD blood units in liquid state is described. It is based on the observation of increased tendency to reversible agglomeration in old erythrocytes in liquid preservation. Erythrocytes ... | [
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PMID:15349 | Renal distal tubular secretory mechanisms in healthy Nigerian subjects. | The distal tubular secretory mechanisms of 30 healthy Nigerians were investigated. This entailed the collection of three different 24 hour urine samples; firstly basal values, secondly during the administration of 15 g of NH4Cl and finally when 5 g of KCl was given addition to 15 g NH4Cl. The basal 24 hour urinary volu... | Renal distal tubular secretory mechanisms in healthy Nigerian subjects. The distal tubular secretory mechanisms of 30 healthy Nigerians were investigated. This entailed the collection of three different 24 hour urine samples; firstly basal values, secondly during the administration of 15 g of NH4Cl and finally when 5 g... | [
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PMID:15345 | [Participation of pancreatic ribonuclease in the digestion processes]. | The authors purified the alkaline ribonuclease obtained from the pancreas and the contents of the superior part of the dog's intestine. A comparative examination of physico-chemical properties and specificity of the separated enzymes was effected. The resulting data prove the pancreas to be the source of the alkaline r... | [Participation of pancreatic ribonuclease in the digestion processes]. The authors purified the alkaline ribonuclease obtained from the pancreas and the contents of the superior part of the dog's intestine. A comparative examination of physico-chemical properties and specificity of the separated enzymes was effected. T... | [
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PMID:15352 | [pH measurements in the vascular wall of dogs with electrically induced thrombosis of the femoral artery]. | Electrically induced thrombosis is often used for pathophysiologic and therapeutic experiments. The pH value of the vascular wall was measured to approach the features of this thrombosis. After inducing thrombosis by direct current, pH value of the intima of femoral artery was found decreased. The anode was inserted in... | [pH measurements in the vascular wall of dogs with electrically induced thrombosis of the femoral artery]. Electrically induced thrombosis is often used for pathophysiologic and therapeutic experiments. The pH value of the vascular wall was measured to approach the features of this thrombosis. After inducing thrombosis... | [
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PMID:15353 | [Gas levels and biochemical changes in cerebrospinal fluid after experimental brain injury: its effect on cerebral circulation and cerebral metabolism as well as its management]. | 1. After brain damage experimentally induced by balloon compression, liquor of the cistern shows a metabolic acidosis with significantly increased lactate level and L/P quotient, and statistically distinct decrease of pH, oxygen tension, and bicarbonate level. 2. There is a considerable disproportion between the change... | [Gas levels and biochemical changes in cerebrospinal fluid after experimental brain injury: its effect on cerebral circulation and cerebral metabolism as well as its management]. 1. After brain damage experimentally induced by balloon compression, liquor of the cistern shows a metabolic acidosis with significantly incr... | [
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PMID:15346 | [Glucose transport across the mucosa of the small intestine]. | The rate of glucose absorption in an isolated loop of the small intestine in rats was measured. The maximum rate of absorption was registered with 3 and 5 per cent concentrations, while 1 and 10 per cent solutions are absorbed at a slower rate. The absorption rate of 5 per cent glucose solution did not materially chang... | [Glucose transport across the mucosa of the small intestine]. The rate of glucose absorption in an isolated loop of the small intestine in rats was measured. The maximum rate of absorption was registered with 3 and 5 per cent concentrations, while 1 and 10 per cent solutions are absorbed at a slower rate. The absorptio... | [
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PMID:15354 | [Fetal heart rate, dip area and acid base observations in breech and vertex deliveries (author's transl)]. | Fetal heart rate (FHR), dip area (DA) and the acid base status (AB) were investigated in breech deliveries (BD) (N= 167) and in group of spontaneously delivered vertex presentations (VP) (NFHR, DA=50; NAB=109). 90 minutes prior to delivery fetal heart rate and dip area were in both groups not significantly different. H... | [Fetal heart rate, dip area and acid base observations in breech and vertex deliveries (author's transl)]. Fetal heart rate (FHR), dip area (DA) and the acid base status (AB) were investigated in breech deliveries (BD) (N= 167) and in group of spontaneously delivered vertex presentations (VP) (NFHR, DA=50; NAB=109). 90... | [
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PMID:15347 | [Protein hydrolysis by pepsin and trypsin at a varying pH]. | The continuity of the pepsin and trysin action on the proteinic substrates with different pH was studied. A short-term incubation of protein with pepsin at high pH intensifies the tryptic effect on this protein, the initial rate of the protein hydrolysis then gains momentum and the possibility of its complete hydrolysi... | [Protein hydrolysis by pepsin and trypsin at a varying pH]. The continuity of the pepsin and trysin action on the proteinic substrates with different pH was studied. A short-term incubation of protein with pepsin at high pH intensifies the tryptic effect on this protein, the initial rate of the protein hydrolysis then ... | [
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PMID:15355 | Nanoencapsulated fluorescence indicator molecules measuring pH and pO2 down to submicroscopical regions in the basis of the optode-principle. | To measure pO2 in gases or fluids and pH in solutions the fluorescence indicators pyrene butyric acid and beta-methylumbelliferone, respectively, were nanoencapsulated to obtain nano-probes for measurement in physiological structures of nano-range. For pH the fluorescence changes of beta-methylumbelliferone were monito... | Nanoencapsulated fluorescence indicator molecules measuring pH and pO2 down to submicroscopical regions in the basis of the optode-principle. To measure pO2 in gases or fluids and pH in solutions the fluorescence indicators pyrene butyric acid and beta-methylumbelliferone, respectively, were nanoencapsulated to obtain ... | [
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PMID:15356 | Effects of phospholipids in the action of acetyl-CoA carboxylase from rat liver. | Acetyl-CoA carboxylase (E.C. 6.4.1.2) was isolated from rat liver. The purified enzyme contains phospholipids with a rather large amount of phosphatidylinositol (26%). Incubation of the purified acetyl-CoA carboxylase with phospholipase A2 (E.C. 3.1.1.4) or with phospholipase D (E.C. 3.1.1.4) diminishes the phospholipi... | Effects of phospholipids in the action of acetyl-CoA carboxylase from rat liver. Acetyl-CoA carboxylase (E.C. 6.4.1.2) was isolated from rat liver. The purified enzyme contains phospholipids with a rather large amount of phosphatidylinositol (26%). Incubation of the purified acetyl-CoA carboxylase with phospholipase A2... | [
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PMID:15368 | The effect Escherichia coli lipopolysaccharide (endotoxin) on the graft-versus-host reaction in mice (IV). | Lipopolysaccharide from Escherichia coli (LPS) administered to mice during the graft-versus-host (GvH) reaction in a single dose of 100 mug stimulated the reaction if it was given on the same day as the parental spleen cells, or inhibited it if given four days before injection of the cells. The GvH reaction was intensi... | The effect Escherichia coli lipopolysaccharide (endotoxin) on the graft-versus-host reaction in mice (IV). Lipopolysaccharide from Escherichia coli (LPS) administered to mice during the graft-versus-host (GvH) reaction in a single dose of 100 mug stimulated the reaction if it was given on the same day as the parental s... | [
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PMID:15389 | Age-dependent resistance of chicken of Salmonella in vitro: antibacterial activity of lysed granule fraction of splenic adherent cells. | Lysed granule fraction was prepared from splenic adherent cells from 0-day-old to 2-month-old chickens and was examined antibacterial activity to Salmonella pullorum and Salmonella sentfenberg. The activity of lysed granule fraction from 2-month-old chickens was exhibited at pH 5.0 but not exhibited at pH 6.0 or 7.0 to... | Age-dependent resistance of chicken of Salmonella in vitro: antibacterial activity of lysed granule fraction of splenic adherent cells. Lysed granule fraction was prepared from splenic adherent cells from 0-day-old to 2-month-old chickens and was examined antibacterial activity to Salmonella pullorum and Salmonella sen... | [
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PMID:15390 | [Pigment Formation by Trichophyton rubrum: Differentiation between T. rubrum and T. mentagrophytes on Serum Albumin Agar (author's transl)]. | On serum albumin agar (bovine albumin) with initial pH-values of 5.0-6.0, Trichophyton rubrum showed a yellow pigmentation, and on the same medium with an initial pH-value of 7.0, a red pigmentation. Strains of Trichophyton mentagrophytes have never shown pigmentation until now, The scarce growth (submerged) of T. rubr... | [Pigment Formation by Trichophyton rubrum: Differentiation between T. rubrum and T. mentagrophytes on Serum Albumin Agar (author's transl)]. On serum albumin agar (bovine albumin) with initial pH-values of 5.0-6.0, Trichophyton rubrum showed a yellow pigmentation, and on the same medium with an initial pH-value of 7.0,... | [
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PMID:15392 | [Pathogenic factors in viral diseases of the central nervous system]. | The possible immunological significance of the different kinds of cells participating in the inflammatory reaction in cerebrospinal infections is to be considered. Presence of plasma cells and occasional perivenous microglial seams in early stages of the neurotropic virus diseases must be regarded as immunological mani... | [Pathogenic factors in viral diseases of the central nervous system]. The possible immunological significance of the different kinds of cells participating in the inflammatory reaction in cerebrospinal infections is to be considered. Presence of plasma cells and occasional perivenous microglial seams in early stages of... | [
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PMID:15393 | ATP-ase activity in the odontoblastic layer of rat incisor. Determination with a radiochemical and a colorimetric method. | The ATP-splitting enzyme activity in odontoblasts isolated from rat incisors has been studied by means of a radiochemical and a colorimetric micromethod. The results with the two methods were virtually identical. The reaction was linear with time for at least 45 min. The pH optimum was found to be 9.8 independently of ... | ATP-ase activity in the odontoblastic layer of rat incisor. Determination with a radiochemical and a colorimetric method. The ATP-splitting enzyme activity in odontoblasts isolated from rat incisors has been studied by means of a radiochemical and a colorimetric micromethod. The results with the two methods were virtua... | [
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PMID:15394 | Characterization of kallikrein from human saliva isolated by use of affinity chromatography. | Kallikrein was isolated from paraffin stimulated saliva by use of two steps affinity chromatography. A610-fold purification of the enzyme was achieved by use of Sepharose 4B conjugated with soy bean trypsin inhibitor and pancreatic trypsin inhibitor. The isoelectric point of kallikrein was found to be pH 4.3 and the mo... | Characterization of kallikrein from human saliva isolated by use of affinity chromatography. Kallikrein was isolated from paraffin stimulated saliva by use of two steps affinity chromatography. A610-fold purification of the enzyme was achieved by use of Sepharose 4B conjugated with soy bean trypsin inhibitor and pancre... | [
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PMID:15395 | Characterization of trypsin-like enzymes from human saliva isolated by use of affinity chromatography. | Paraffin-stimulated whole mixed saliva was collected from 6 individuals and pooled. Three trypsin-like enzymes from saliva supernatant and two from the saliva sediment were isolated by use of affinity chromatography on a soybean trypsin inhibitor Sepharose 4 B column. The isoelectric points for these enzymes were pI 8.... | Characterization of trypsin-like enzymes from human saliva isolated by use of affinity chromatography. Paraffin-stimulated whole mixed saliva was collected from 6 individuals and pooled. Three trypsin-like enzymes from saliva supernatant and two from the saliva sediment were isolated by use of affinity chromatography o... | [
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PMID:15396 | Myxofibrosarcoma. A study of 30 cases. | A series of 30 myxofibrosarcomas is described. These malignant soft tissue tumours are characterized by a mucoid and nodular appearance, a coarse plexiform capillary pattern, and they are mostly seen subcutaneously (26 out of 30) in the extremities (24 out of 30) and trunk (4 out of 30) elderly people. Histochemical st... | Myxofibrosarcoma. A study of 30 cases. A series of 30 myxofibrosarcomas is described. These malignant soft tissue tumours are characterized by a mucoid and nodular appearance, a coarse plexiform capillary pattern, and they are mostly seen subcutaneously (26 out of 30) in the extremities (24 out of 30) and trunk (4 out ... | [
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PMID:15399 | Disposition of three benzodiazepines after single oral administration in man. | Three benzodiazepines in equipotent doses: oxazepam 15 mg, dipotassium chlorazepate 10 mg and diazepam 5 mg, were administered in single, oral doses to seven healthy volunteers in a three-way cross-over study. The serum concentrations of oxazepam, N-desmethyldiazepam and diazepam were followed for 72 hours by gas chrom... | Disposition of three benzodiazepines after single oral administration in man. Three benzodiazepines in equipotent doses: oxazepam 15 mg, dipotassium chlorazepate 10 mg and diazepam 5 mg, were administered in single, oral doses to seven healthy volunteers in a three-way cross-over study. The serum concentrations of oxaz... | [
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PMID:15400 | Biological studies on the effects of some therapeutic procedures used in psychiatry. | The glucose, lactate, and pyruvate levels, the lactate/pyruvate ratio and pH were studied in serum and CSF of patients with schizophrenia, reactive psychosis, symptomatic or circular psychosis under the effect of atropine coma, ES and pentetrazole convulsions, tranquilizer treatment and combined therapy. Convulsive the... | Biological studies on the effects of some therapeutic procedures used in psychiatry. The glucose, lactate, and pyruvate levels, the lactate/pyruvate ratio and pH were studied in serum and CSF of patients with schizophrenia, reactive psychosis, symptomatic or circular psychosis under the effect of atropine coma, ES and ... | [
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PMID:15401 | Solubilization of particle-linked urate oxidase by different agents. | Urate oxidase was mostly recovered in a 40 000 g for 20 min subcellular fraction from conventional homogenated. Different agents were able to solubilize the sedimentable enzyme when tested on this crude peroxisomal fraction. The agents increased also total enzyme activity which was recovered in supernatants after centf... | Solubilization of particle-linked urate oxidase by different agents. Urate oxidase was mostly recovered in a 40 000 g for 20 min subcellular fraction from conventional homogenated. Different agents were able to solubilize the sedimentable enzyme when tested on this crude peroxisomal fraction. The agents increased also ... | [
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PMID:15402 | Effects of acetylsalicylate on alkalinization, acid secretion and electrogenic properties in the isolated gastric mucosa. | The effects of acetylsalicylate (ASA) on the in vitro secretory and electrical properties of Necturus and Rana temporaria gastric mucosa have been studied. The gastric antrum alkalinized the luminal surface, while in the fundus it is likely that acidificaiton and alkalinization occur simultaneously and that net secreti... | Effects of acetylsalicylate on alkalinization, acid secretion and electrogenic properties in the isolated gastric mucosa. The effects of acetylsalicylate (ASA) on the in vitro secretory and electrical properties of Necturus and Rana temporaria gastric mucosa have been studied. The gastric antrum alkalinized the luminal... | [
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PMID:15403 | Lower body negative pressure and effects of autonomic heart blockade on cardiovascular responses. | Heart rate, arterial pressure and cardiac output were recorded in eight healthy male volunteers during exposure to 80 mmHg of lower body negative pressure (LBNP) in the supine position before and after beta-adrenergic and combined beta-adrenergic and parasympathetic blockade of the heart as induced by the i.v. administ... | Lower body negative pressure and effects of autonomic heart blockade on cardiovascular responses. Heart rate, arterial pressure and cardiac output were recorded in eight healthy male volunteers during exposure to 80 mmHg of lower body negative pressure (LBNP) in the supine position before and after beta-adrenergic and ... | [
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PMID:15405 | Partial correction of hypertension by angiotensin II blockade in a patient with phaeochromocytoma. | This case report describes a patient with malignant hypertension and phaeochromocytoma in whom blockade of angiotensin II receptors by the competitive antagonist 1-sar-8-ala-angiotensin II (Saralasin) resulted in a partial correction of the elevated BP. Plasma renin activity was high and rose further during the blockad... | Partial correction of hypertension by angiotensin II blockade in a patient with phaeochromocytoma. This case report describes a patient with malignant hypertension and phaeochromocytoma in whom blockade of angiotensin II receptors by the competitive antagonist 1-sar-8-ala-angiotensin II (Saralasin) resulted in a partia... | [
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PMID:15407 | Neurochemical evidence for histamine acting as a transmitter in mammalian brain. | HA, besides its function in immune processes, is probably a neurotransmitter in mammalian brain. It is synthesized by a specific decarboxylase localized in the cytoplasm of nerve endings. It is stored in synaptic vesicles. Its release might depend on nerve-impulse flow; specific receptors to this amine have been eviden... | Neurochemical evidence for histamine acting as a transmitter in mammalian brain. HA, besides its function in immune processes, is probably a neurotransmitter in mammalian brain. It is synthesized by a specific decarboxylase localized in the cytoplasm of nerve endings. It is stored in synaptic vesicles. Its release migh... | [
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PMID:15417 | Purine nucleotides. | The existence of nonadrenergic, noncholinergic nerve components in the autonomic nervous system is now well established. They are strongly represented in the gastrointestinal tract of all vertebrates and have been identified in a variety of other organs, including lung, trachea, bladder, esophagus, eye, seminal vesicle... | Purine nucleotides. The existence of nonadrenergic, noncholinergic nerve components in the autonomic nervous system is now well established. They are strongly represented in the gastrointestinal tract of all vertebrates and have been identified in a variety of other organs, including lung, trachea, bladder, esophagus, ... | [
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PMID:15419 | Glucocorticoid regulation of the serotonergic system of the brain. | Glucorticoids at concentrations above 10(-7) M stimulate the uptake of tryptophan by brain synaptosomes. Furthermore, in both developmental and drug-induced (reserpine and ethanol) increases of brain tryptophan hydroxylase activity, glucocorticoids are required in order for the increases to occur. If de novo enzyme syn... | Glucocorticoid regulation of the serotonergic system of the brain. Glucorticoids at concentrations above 10(-7) M stimulate the uptake of tryptophan by brain synaptosomes. Furthermore, in both developmental and drug-induced (reserpine and ethanol) increases of brain tryptophan hydroxylase activity, glucocorticoids are ... | [
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PMID:15421 | A neurobiological role for a protein activator of cyclic nucleotide phosphodiesterase. | This work supports the idea that PDEA is bound and stored in brain particulate fraction. The release of PDEA into cytosol where the activator-sensitive PDE is located, is the first event in the process of the regulation of cAMP metabolism and inactivation. PDEA is released by cAMP-dependent phosphorylation of the activ... | A neurobiological role for a protein activator of cyclic nucleotide phosphodiesterase. This work supports the idea that PDEA is bound and stored in brain particulate fraction. The release of PDEA into cytosol where the activator-sensitive PDE is located, is the first event in the process of the regulation of cAMP metab... | [
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PMID:15422 | Cellular depolarization and cyclic nucleotide content in central nervous system. | There is ample evidence indicating that cAMP and cGMP content in mamalian brain is markedly influenced by cellular depolarization. The relationships between the two cyclic nucleotides and the complex process of cellular depolarization, which in turn leads to extensive functional and metabolic consequences are incomplet... | Cellular depolarization and cyclic nucleotide content in central nervous system. There is ample evidence indicating that cAMP and cGMP content in mamalian brain is markedly influenced by cellular depolarization. The relationships between the two cyclic nucleotides and the complex process of cellular depolarization, whi... | [
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PMID:15426 | Long-term regulatory mechanisms for tyrosine hydroxylase in sympathetic ganglia and carotid body. | The delayed activation of TH elicited by hypoxia in carotid body indirectly suggests that the release of dopamine is part of the responses elicited by hypoxia. The TH activation appears to be independent from nicotinic receptor stimulation and can be abolished by dopaminergic receptor stimulation. Dexamethasone also in... | Long-term regulatory mechanisms for tyrosine hydroxylase in sympathetic ganglia and carotid body. The delayed activation of TH elicited by hypoxia in carotid body indirectly suggests that the release of dopamine is part of the responses elicited by hypoxia. The TH activation appears to be independent from nicotinic rec... | [
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PMID:15427 | [Sexual development of boys, treated surgically for dystopia of testicles (author's transl)]. | A clinical follow-up examination was made in a group of 208 children and adolescents who had undergone surgical treatment for congenital cryptorchid testis (unilateral or bilateral) between 2 and 10 years before. The puberal growth and maturing process of the primary and secondary sex characteristics of this morbidity ... | [Sexual development of boys, treated surgically for dystopia of testicles (author's transl)]. A clinical follow-up examination was made in a group of 208 children and adolescents who had undergone surgical treatment for congenital cryptorchid testis (unilateral or bilateral) between 2 and 10 years before. The puberal g... | [
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PMID:15432 | Study of the priming effect of interferon in L cells. II. Metabolic requirements for the development of primed state. | Actinomycin D at a concentration inhibitory for nucleolar RNA synthesis did not influence the development of priming. Higher concentrations of the drug and long-term alpha-amanitin or cycloheximide pretreatments, inhibitory for heterogenous nuclear RNA synthesis, prevented the establishment of the primed state. The inh... | Study of the priming effect of interferon in L cells. II. Metabolic requirements for the development of primed state. Actinomycin D at a concentration inhibitory for nucleolar RNA synthesis did not influence the development of priming. Higher concentrations of the drug and long-term alpha-amanitin or cycloheximide pret... | [
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PMID:15433 | Influence of polypeptide molecular and side chain lengths and of side chain steric location on the kinetics of basic polypeptide-induced sensitization of primate cells to transfection. | Kinetics of sensitization of chimpanzee cell sheets to transfection by poliovirus RNA was determined for 5 basic polypeptides. With basic olypeptide hydrobromide at 100 microng/ml, initial sensitization rate was faster for poly-L-ornithine of average molecular weight (AMW) 15500 than of AMW 105000, and much faster for ... | Influence of polypeptide molecular and side chain lengths and of side chain steric location on the kinetics of basic polypeptide-induced sensitization of primate cells to transfection. Kinetics of sensitization of chimpanzee cell sheets to transfection by poliovirus RNA was determined for 5 basic polypeptides. With bas... | [
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PMID:15434 | Susceptibility of various cell lines to virulent an attenuated strains of pseudorabies virus at supraoptimal temperature. | Replication of virulent and attenuated strains of pseudorabies virus (PRV) at supraoptimal temperature was studied in rabbit lung (ZP), pig kidney (PS), and BHK-21 cells adapted and non-adapted to 40 degrees C and L, HeLa and human amniotic (Am) cells non-adapted to 40 degrees C. The temperature of 40 degreeC did not i... | Susceptibility of various cell lines to virulent an attenuated strains of pseudorabies virus at supraoptimal temperature. Replication of virulent and attenuated strains of pseudorabies virus (PRV) at supraoptimal temperature was studied in rabbit lung (ZP), pig kidney (PS), and BHK-21 cells adapted and non-adapted to 4... | [
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PMID:15435 | Effect of streptovirudin on parainfluenza 3 virus multiplication. | Streptovirudin (SV) in a concentration of 100 microng/ml reduced the multiplication of parainfluenza 3 virus by about 3.5 log units. When uninfected WISH cells were treated for 2 and 12 hours with 100 mug/ml of SV, 3H-thymidineincorporation was decreased, but no marked differences were observed in the incorporation of ... | Effect of streptovirudin on parainfluenza 3 virus multiplication. Streptovirudin (SV) in a concentration of 100 microng/ml reduced the multiplication of parainfluenza 3 virus by about 3.5 log units. When uninfected WISH cells were treated for 2 and 12 hours with 100 mug/ml of SV, 3H-thymidineincorporation was decreased... | [
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PMID:15436 | Sunday Canyon virus, a new ungrouped agent from the tick Argas (A.) cooleyi in Texas. | A new arbovirus was isolated from Texas, U.S.A., populations of the Cliff Swallow parasits Argas (Argas) cooleyi Kohls and Hoogstraal, 1960. The virus, named Sunday Canyon, is serological urelated to any of 185 arbovirus strains or 20 other viral agents with which it was compared. Morphologically it resembles Bunyamwer... | Sunday Canyon virus, a new ungrouped agent from the tick Argas (A.) cooleyi in Texas. A new arbovirus was isolated from Texas, U.S.A., populations of the Cliff Swallow parasits Argas (Argas) cooleyi Kohls and Hoogstraal, 1960. The virus, named Sunday Canyon, is serological urelated to any of 185 arbovirus strains or 20... | [
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PMID:15437 | Appearance and some unusual features of Epstein-Barr virus antibody production in infectious mononucleosis and other health disorders. | The indirect immunofluorescence (IF) test and the complement-fixation reaction (CFR) were used in examination of over 1500 sera obtained from patients with infectious mononucleosis (IM) and other health disorders. The evidence obtained supports a direct aetiological relationship between Epstein-Barr virus (EBV) and IM ... | Appearance and some unusual features of Epstein-Barr virus antibody production in infectious mononucleosis and other health disorders. The indirect immunofluorescence (IF) test and the complement-fixation reaction (CFR) were used in examination of over 1500 sera obtained from patients with infectious mononucleosis (IM)... | [
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PMID:15438 | Characteristics of poliovirus type 3 strains after passage through monkey central nervous system. | Cercopithecus aethiops monkeys were inoculated intracerebrally with Sabin's type 3 polivoirus strain, and with strains isolated from subjects vaccinated with Leon 12a1b and from their contacts. Sample of brain, spinal cord, kidneys, lymph nodes, blood and spinal fluid were taken. From these materials, (except of kidney... | Characteristics of poliovirus type 3 strains after passage through monkey central nervous system. Cercopithecus aethiops monkeys were inoculated intracerebrally with Sabin's type 3 polivoirus strain, and with strains isolated from subjects vaccinated with Leon 12a1b and from their contacts. Sample of brain, spinal cord... | [
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PMID:15439 | 6-MFA, an antiviral agent from Aspergillus ochraceus ATCC 28706: influence of body weight and mineral oil administration of the antiviral activity in mice. | Sera obtained from mice treated with 6-MFA, an antiviral agent from Aspergillus ochraceus ATCC 28706 showing high interferon activity, could be transferred to healthy animals to make them resistant to Semliki Forest Virus (SFV) infection. Body weight of mice directly influenced, within limits, the proportion of treated... | 6-MFA, an antiviral agent from Aspergillus ochraceus ATCC 28706: influence of body weight and mineral oil administration of the antiviral activity in mice. Sera obtained from mice treated with 6-MFA, an antiviral agent from Aspergillus ochraceus ATCC 28706 showing high interferon activity, could be transferred to healt... | [
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PMID:15440 | Disintegration of red clover mottle virus virions under different conditions of storage in vitro. | Red clover mottle virus was kept in 0.1 M phosphate buffer, pH 7.0, at 4, --20 and --60 degrees C for 1 and 4 weeks and 3 months. The degree of virion disintegration was the highest at --20 degrees C and the lowest at 4 degrees C. Two cycles of freezing and thawing destroyed the virions. In frozen samples (at both --20... | Disintegration of red clover mottle virus virions under different conditions of storage in vitro. Red clover mottle virus was kept in 0.1 M phosphate buffer, pH 7.0, at 4, --20 and --60 degrees C for 1 and 4 weeks and 3 months. The degree of virion disintegration was the highest at --20 degrees C and the lowest at 4 de... | [
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PMID:15441 | Effect of a proteolytic enzyme inhbitor on influenza virus replication. | N-tosyl-L-phenylalanyl chloromethane patially inhibited the multiplicatiion of fowl plague virus (FPV) in infected cells. The capacity of the inhibitor to suppress the muliplication of FPV depended on the host cell system. | Effect of a proteolytic enzyme inhbitor on influenza virus replication. N-tosyl-L-phenylalanyl chloromethane patially inhibited the multiplicatiion of fowl plague virus (FPV) in infected cells. The capacity of the inhibitor to suppress the muliplication of FPV depended on the host cell system. | [
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PMID:15442 | Structure of inclusion bodies of cabbage black ring virus. | Inclusions in cells of Nicotiana glutinosa infected with a horse-radish strain of cabbage black ring virus (CBRV) were investigated on ultrathin sections. Large amorphous inclusions contained cellular constitutents showing usually no pathological alterations. Lamellar inclusions (bundles, circular inclusions, pinwheels... | Structure of inclusion bodies of cabbage black ring virus. Inclusions in cells of Nicotiana glutinosa infected with a horse-radish strain of cabbage black ring virus (CBRV) were investigated on ultrathin sections. Large amorphous inclusions contained cellular constitutents showing usually no pathological alterations. L... | [
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PMID:15443 | An iridovirus from larvae of Culiseta annulata and Culex territans. | Field-collected 4th instar larvae of Culiseta annulata and Culex territans were found to be infected with mosquito iridescent virus (MIV). Ultrathin sections revealed the presence in infected cells of different types of immature virus particles of an average diameter of 180 and 190 nm respectively. | An iridovirus from larvae of Culiseta annulata and Culex territans. Field-collected 4th instar larvae of Culiseta annulata and Culex territans were found to be infected with mosquito iridescent virus (MIV). Ultrathin sections revealed the presence in infected cells of different types of immature virus particles of an a... | [
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PMID:15447 | Psychological aspects of cardiac arrhythmia. | A review of data from a wide spectrum of research studies suggests that psychological-emotional factors can significantly influence and alter the incidence of cardiac arrhythmia. While the existing data are, in many cases, difficult to interpret because of theoretical and methodological problems, sufficient evidence do... | Psychological aspects of cardiac arrhythmia. A review of data from a wide spectrum of research studies suggests that psychological-emotional factors can significantly influence and alter the incidence of cardiac arrhythmia. While the existing data are, in many cases, difficult to interpret because of theoretical and me... | [
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PMID:15448 | Internal mammary artery graft for ischemic heart disease. Effect of revascularization on clinical status and survival. | Four hundred consecutive patients, 80 percent of whom had multiple vessel obstruction, received a single internal mammary artery graft (121 patients) alone or combined with vein grafts (279 patients) in 1971 and 1972. Four patients died during or within 30 days of the operation. Sixteen patients had intraoperative infa... | Internal mammary artery graft for ischemic heart disease. Effect of revascularization on clinical status and survival. Four hundred consecutive patients, 80 percent of whom had multiple vessel obstruction, received a single internal mammary artery graft (121 patients) alone or combined with vein grafts (279 patients) i... | [
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PMID:15449 | Enkephalin, drug addiction and acupuncture. | From the results of clinical and basic research, there is clear evidence that acupuncture analgesia is closely associated with the nervous system, especially the central nervous system. Stimulation of certain acupuncture loci which have been used for analgesia during operations also can calm the withdrawal symptoms of ... | Enkephalin, drug addiction and acupuncture. From the results of clinical and basic research, there is clear evidence that acupuncture analgesia is closely associated with the nervous system, especially the central nervous system. Stimulation of certain acupuncture loci which have been used for analgesia during operatio... | [
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PMID:15450 | The Silver-Russel syndrome: a case with sexual ambiguity, and a review of literature. | A 38-month-old patient with Silver-Russel syndrome (SRS) and ambiguous genitalia had a 46,XY karyotype on leukocyte and fibroblast cultures. This is the third SRS child with ambiguous genitalia described in the literature. In a review of the findings in 148 reported cases of the syndrome, abnormalities occurring in ove... | The Silver-Russel syndrome: a case with sexual ambiguity, and a review of literature. A 38-month-old patient with Silver-Russel syndrome (SRS) and ambiguous genitalia had a 46,XY karyotype on leukocyte and fibroblast cultures. This is the third SRS child with ambiguous genitalia described in the literature. In a review... | [
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PMID:15451 | Detection of heterozygotes for tyrosinase-negative oculocutaneous albinism by hairbulb tyrosinase assay. | Five heterozygotes for ty-neg OCA had absent or markedly reduced hairbulb tyrosinase activity, when compared to normally pigmented control subjects. Clinically, all five were fully pigmented and could not be distinguished from the normal control subjects. It is proposed that the quantitative hairbulb tyrosinase assay c... | Detection of heterozygotes for tyrosinase-negative oculocutaneous albinism by hairbulb tyrosinase assay. Five heterozygotes for ty-neg OCA had absent or markedly reduced hairbulb tyrosinase activity, when compared to normally pigmented control subjects. Clinically, all five were fully pigmented and could not be disting... | [
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PMID:15452 | Very low arylsulfatase A and cerebroside sulfatase activities in leukocytes of healthy members of metachromatic leukodystrophy family. | Very low levels of arylsulfatase A (ASA) have been found in the leukocytes of healthy members of a metachromatic leukodystrophy (MLD) family. The cerebroside sulfate sulfatase (CSS) activities in the same individuals are about 10% of the control level. Arguments favoring a dominant mutation different from that of class... | Very low arylsulfatase A and cerebroside sulfatase activities in leukocytes of healthy members of metachromatic leukodystrophy family. Very low levels of arylsulfatase A (ASA) have been found in the leukocytes of healthy members of a metachromatic leukodystrophy (MLD) family. The cerebroside sulfate sulfatase (CSS) act... | [
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PMID:15456 | Factors determining human chorion laeve permeability in vitro. | An increased mean diffusion permeability across human chorion laeve in vitro was measured for meperidine (D = 5.26 x 10(-6) cm.2 sec.-1) and diazepam (D = 4.51 X 10(-6) cm.2 sec.-1). These values corresponded to large chloroform-buffer partition coefficients (49 and 29) measured for these two compounds. Diffusion perme... | Factors determining human chorion laeve permeability in vitro. An increased mean diffusion permeability across human chorion laeve in vitro was measured for meperidine (D = 5.26 x 10(-6) cm.2 sec.-1) and diazepam (D = 4.51 X 10(-6) cm.2 sec.-1). These values corresponded to large chloroform-buffer partition coefficient... | [
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PMID:15457 | Effects of calcium on renin and aldosterone in the rat. | CaCl2 suppresses the plasma renin activity (PRA) response to Na+ deprivation in the rat. The purpose of the present study is:1) to determine if the effect of Ca2+ on PRA is modified by the anion delivered with Ca2+, and 2) to evaluate the effect of Ca2+ loading on aldosterone production. PRA and in vitro aldosterone pr... | Effects of calcium on renin and aldosterone in the rat. CaCl2 suppresses the plasma renin activity (PRA) response to Na+ deprivation in the rat. The purpose of the present study is:1) to determine if the effect of Ca2+ on PRA is modified by the anion delivered with Ca2+, and 2) to evaluate the effect of Ca2+ loading on... | [
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PMID:15454 | Immunopathological aspects of hepatitis type B. | Tissue samples from 180 unselected necropsy cases of various forms of hepatitis were examined by histopathology and immunofluorescence. The hepatitis forms studied included acute fulminant hepatitis (28 patients), subacute hepatitis (48 patients), acute fatal hepatitis (24 patients), chronic aggressive hepatitis (26 pa... | Immunopathological aspects of hepatitis type B. Tissue samples from 180 unselected necropsy cases of various forms of hepatitis were examined by histopathology and immunofluorescence. The hepatitis forms studied included acute fulminant hepatitis (28 patients), subacute hepatitis (48 patients), acute fatal hepatitis (2... | [
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PMID:15458 | Metabolic features of isolated rat lung cells. I. Factors controlling glucose utilization. | Isolated rat lung cell suspensions were prepared by collagenase digestion of the lung stroma. These cells were functionally competent as judged, among other criteria, by their constant rates of oxygen uptake and glucose utilization. An important metabolic feature of these cells is that they display very high glycolytic... | Metabolic features of isolated rat lung cells. I. Factors controlling glucose utilization. Isolated rat lung cell suspensions were prepared by collagenase digestion of the lung stroma. These cells were functionally competent as judged, among other criteria, by their constant rates of oxygen uptake and glucose utilizati... | [
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PMID:15459 | Glucose and lactate kinetics in burn shock. | We studied the glucose and lactate kinetics during burn shock by means of the primed constant infusion of [6-3H]glucose and Na-L-(+)-[U-14C]lactate. We found an early postburn hyperglycemia that was due to an increased rate of appearance (Ra) of glucose. Later, the ability of the tissues to extract glucose became impai... | Glucose and lactate kinetics in burn shock. We studied the glucose and lactate kinetics during burn shock by means of the primed constant infusion of [6-3H]glucose and Na-L-(+)-[U-14C]lactate. We found an early postburn hyperglycemia that was due to an increased rate of appearance (Ra) of glucose. Later, the ability of... | [
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PMID:15455 | Treatment of Bacteroides endocarditis with carbenicillin. | A heroin addict developed acute bacterial endocarditis with Streptococcus viridans and Bacteroides melaninogenicus. Although blood cultures became negative during penicillin G and clindamycin therapy there was little clinical response. Prompt clinical improvement was achieved with intravenous carbenicillin in a dose of... | Treatment of Bacteroides endocarditis with carbenicillin. A heroin addict developed acute bacterial endocarditis with Streptococcus viridans and Bacteroides melaninogenicus. Although blood cultures became negative during penicillin G and clindamycin therapy there was little clinical response. Prompt clinical improvemen... | [
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PMID:15460 | pH gradients in the developing teeth of young mice from autoradiography of [14C]DMO. | The distribution of the weak acid [14C]DMO was studied in mice, 10-19 days old, by an autoradiographic technique that does not translocate or remove the compound. Calculations of pH values in areas of the developing teeth of these animals were made by comparing the photometric density of the distribution of [14C]DMO, a... | pH gradients in the developing teeth of young mice from autoradiography of [14C]DMO. The distribution of the weak acid [14C]DMO was studied in mice, 10-19 days old, by an autoradiographic technique that does not translocate or remove the compound. Calculations of pH values in areas of the developing teeth of these anim... | [
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PMID:15461 | Computer simulation of ischemic rat heart purine metabolism. II. Model behavior. | The behavior of a model for the partial depletion of adenine nucleotides in the perfused rat heart has been compared for ischemic and high coronary flow anoxic conditions. The accumulation of noradrenaline in the interstitial fluid greatly activates adenylate cyclase ultimately resulting in the degradation of 11.02 mic... | Computer simulation of ischemic rat heart purine metabolism. II. Model behavior. The behavior of a model for the partial depletion of adenine nucleotides in the perfused rat heart has been compared for ischemic and high coronary flow anoxic conditions. The accumulation of noradrenaline in the interstitial fluid greatly... | [
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PMID:15462 | Psychoneuroendocrinology of affective disorder: an overview. | Neuroendocrine function has been reported by several workers to be abnormal in affective disorder. It has been shown that neurotransmitters (noradrenaline, dopamine, and serotinin) are involved in the regulation of neuroendocrine function. Several biological hypotheses of affective disorder have implicated a defect in ... | Psychoneuroendocrinology of affective disorder: an overview. Neuroendocrine function has been reported by several workers to be abnormal in affective disorder. It has been shown that neurotransmitters (noradrenaline, dopamine, and serotinin) are involved in the regulation of neuroendocrine function. Several biological ... | [
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PMID:15463 | Spinal cord injury: a role for the psychiatrist. | The initial psychiatric evaluation of individuals with spinal cord injuries should focus on the patients' coping strategies; this information is an essential part of the treatment and rehabilitation plan. Psychiatrists can also work effectively with staff members in groups designed to ease the strain of working with se... | Spinal cord injury: a role for the psychiatrist. The initial psychiatric evaluation of individuals with spinal cord injuries should focus on the patients' coping strategies; this information is an essential part of the treatment and rehabilitation plan. Psychiatrists can also work effectively with staff members in grou... | [
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PMID:15464 | Characteristics of release of duodenal gastrin. | Duodenal gastrin release in the dog was studied after mucosal antrectomy with intact duodenal innervation, following which basal gastrin levels fell. Acetylcholine at pH 7 but not at pH 1.5 and insulin hypoglycemia but not 2-deoxyglucose release duodenal gastrin. Glycine (pH7), physiologic saline (pH 7), and balloon di... | Characteristics of release of duodenal gastrin. Duodenal gastrin release in the dog was studied after mucosal antrectomy with intact duodenal innervation, following which basal gastrin levels fell. Acetylcholine at pH 7 but not at pH 1.5 and insulin hypoglycemia but not 2-deoxyglucose release duodenal gastrin. Glycine ... | [
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PMID:15465 | Intestinal brush border enzymes after short-term mesenteric ischemia. | The total activities of sucrase, trehalase, amino-peptidase, and gamma-glutamyltransferase in the isolated brush border of the entire small bowel are reduced to 35, 55, 33, and 21 per cent, respectively, of control values (p less than 0.001) 2 hours after a 45 minute occlusion of the superior mesenteric artery. Since b... | Intestinal brush border enzymes after short-term mesenteric ischemia. The total activities of sucrase, trehalase, amino-peptidase, and gamma-glutamyltransferase in the isolated brush border of the entire small bowel are reduced to 35, 55, 33, and 21 per cent, respectively, of control values (p less than 0.001) 2 hours ... | [
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PMID:15467 | Rapid intubation with fazadinium. A comparison of fazadinium with suxamethonium and alcuronium. | The speed of onset and intubation conditions have been compared for suxamethonium 1 mg/kg, alcuronium 0-32 mg/kg and fazadinium 1 mg/kg and 1-25 mg/kg. Fazadinium 1 mg/kg was not significantly different in times to intubation from suxamethonium although the latter gave a highly significant greater number of patients wi... | Rapid intubation with fazadinium. A comparison of fazadinium with suxamethonium and alcuronium. The speed of onset and intubation conditions have been compared for suxamethonium 1 mg/kg, alcuronium 0-32 mg/kg and fazadinium 1 mg/kg and 1-25 mg/kg. Fazadinium 1 mg/kg was not significantly different in times to intubatio... | [
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PMID:15473 | Depression of phase-transition temperature in a model cell membrane by local anesthetics. | Disordering, fluidizing and dilating effects of anesthetics upon cell membranes are well recognized. The fluidization can be precisely measured with phospholipid membranes. When phospholipids are dispersed in water, they form globules of bilayer structure. These model membranes undergo transition between crystalline (o... | Depression of phase-transition temperature in a model cell membrane by local anesthetics. Disordering, fluidizing and dilating effects of anesthetics upon cell membranes are well recognized. The fluidization can be precisely measured with phospholipid membranes. When phospholipids are dispersed in water, they form glob... | [
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PMID:15474 | Mutagenicity of halogenated ether anesthetics. | An in vitro microbial assay system employing two histidine-dependent strains of Salmonella typhimurium, TA1535 and TA100, was used to test the mutagenicities of enflurane, methoxyflurane, isoflurane and fluroxene. Enflurane, isoflurane and fluroxene in concentrations ranging from 0.01 to 30 per cent and methoxyflurane ... | Mutagenicity of halogenated ether anesthetics. An in vitro microbial assay system employing two histidine-dependent strains of Salmonella typhimurium, TA1535 and TA100, was used to test the mutagenicities of enflurane, methoxyflurane, isoflurane and fluroxene. Enflurane, isoflurane and fluroxene in concentrations rangi... | [
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PMID:15471 | Mechanisms of chronotropic effects of volatile inhalation anesthetics. | The chronotropic effects of all currently available volatile anesthetics were investigated in isolated rat atrial preparations. Anesthetic ethers, diethyl ether, methoxyflurane, and enflurane elicited a dose-dependent positive chronotropic effect. Fluroxene produced a slight depression at low concentrations. The haloge... | Mechanisms of chronotropic effects of volatile inhalation anesthetics. The chronotropic effects of all currently available volatile anesthetics were investigated in isolated rat atrial preparations. Anesthetic ethers, diethyl ether, methoxyflurane, and enflurane elicited a dose-dependent positive chronotropic effect. F... | [
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PMID:15475 | [Study of a new anesthetic agent: Etomidate (R 26490). Unusual electroencephalic aspects]. | Etomidate or R 26490 is a new hypnotic agent produced by JANSSEN and al. in 1971. The first human experimentation was performed in 1972. The authors used Etomidate for 300 anaesthetics given for neuroradiological investigations. Two protocols were used for study: 25 anaesthetics were given with Etomidate as sole anaest... | [Study of a new anesthetic agent: Etomidate (R 26490). Unusual electroencephalic aspects]. Etomidate or R 26490 is a new hypnotic agent produced by JANSSEN and al. in 1971. The first human experimentation was performed in 1972. The authors used Etomidate for 300 anaesthetics given for neuroradiological investigations. ... | [
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PMID:15472 | Arrhythmic doses of epinephrine and dopamine during halothane, enflurane, methoxyflurane, and fluroxene anesthesia in goats. | The cardiac arrhythmicity of epinephrine and dopamine was compared in awake goats and during approximate equivalent levels of halothane, enflurane, methoxyflurane, and fluroxene anesthesia. The arrhythmic threshold dose for epinephrine and dopamine was significantly (p less than 0.05) reduced during halothane anesthesi... | Arrhythmic doses of epinephrine and dopamine during halothane, enflurane, methoxyflurane, and fluroxene anesthesia in goats. The cardiac arrhythmicity of epinephrine and dopamine was compared in awake goats and during approximate equivalent levels of halothane, enflurane, methoxyflurane, and fluroxene anesthesia. The a... | [
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PMID:15476 | [Effects of Etomidate on ventilation and blood gases]. | 17 surgical patients, agent 49 to 87, are studied. Their anaesthetic induction was performed by an intravenous injection of Etomidate on a 0,23 mg/kg body weight basiis. Respiratory frequency and minute ventilation were put on continuous recording, PO2, PCO2 and arterial blood pH were measured 1,3 and 5 minutes after i... | [Effects of Etomidate on ventilation and blood gases]. 17 surgical patients, agent 49 to 87, are studied. Their anaesthetic induction was performed by an intravenous injection of Etomidate on a 0,23 mg/kg body weight basiis. Respiratory frequency and minute ventilation were put on continuous recording, PO2, PCO2 and ar... | [
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PMID:15477 | [Hemodynamic effects of Etomidate]. | Hemodynamic variations due to Etomidate administration were studies in 10 patients submitted to artificial ventilation. Etomidate was given at a 0.37 mg/kg B.W. dosage. Cardiac rate, mean arterial B.P., C.V.P., mean arteial pulmonary pressure, mean pulmonary capillary pressure and cardiac output were investigated. From... | [Hemodynamic effects of Etomidate]. Hemodynamic variations due to Etomidate administration were studies in 10 patients submitted to artificial ventilation. Etomidate was given at a 0.37 mg/kg B.W. dosage. Cardiac rate, mean arterial B.P., C.V.P., mean arteial pulmonary pressure, mean pulmonary capillary pressure and ca... | [
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PMID:15478 | [Use of the diazepam-pentazocine (pentazepam) combination in anesthesiology]. | The authors report on 50 surgical or endoscopic cases in which local or regional anaesthesia was completed with a combination of diazepam and pentazocine (Pentazapam). This "diazanalgesia" was performed either as a routine or as a complement to regional anaesthesia (mostly an epidural) in which restlessness or insuffi... | [Use of the diazepam-pentazocine (pentazepam) combination in anesthesiology]. The authors report on 50 surgical or endoscopic cases in which local or regional anaesthesia was completed with a combination of diazepam and pentazocine (Pentazapam). This "diazanalgesia" was performed either as a routine or as a complement... | [
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PMID:15479 | [Toxico-pharmacologic study of a curarimimetic, AH 8165, in relation to storage time]. | The toxicological and pharmacological study of a non depolarizing curariform drug AH 8165 was performed under various conditions of storage, duration and temperature (duration: 1 month 2 years; temperature: 4 degrees C to 70 degrees C). It shows that this drug ought to be kept a low temperature for storage (in the rang... | [Toxico-pharmacologic study of a curarimimetic, AH 8165, in relation to storage time]. The toxicological and pharmacological study of a non depolarizing curariform drug AH 8165 was performed under various conditions of storage, duration and temperature (duration: 1 month 2 years; temperature: 4 degrees C to 70 degrees ... | [
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PMID:15480 | [Effects of Alfatesine (ct 1341) on cerebral blood flow and metabolism in man. Global and regional changes]. | The effects of Alfatesine on local cerebral blood flow and on cerebral oxygen consumption were studied in 5 normal subjects and in 6 patients suffering from diffuse vascular repercussion of cerebral distress. There is a 75 p. 100 fall in cerebral blood flow in the gray substance and a parallel fall in oxygen consumpt... | [Effects of Alfatesine (ct 1341) on cerebral blood flow and metabolism in man. Global and regional changes]. The effects of Alfatesine on local cerebral blood flow and on cerebral oxygen consumption were studied in 5 normal subjects and in 6 patients suffering from diffuse vascular repercussion of cerebral distress. T... | [
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PMID:15481 | [Correction of the alphamimetic effects of metaraminol by nicergoline]. | In this work, the authors are studying the cardio-vascular effects of nicergoline. To do so, the drug is made to compete with metaraminol whose dominant alphamimetic effects are known. This experimentation was performed in 7 patients in coma stage III or IV and whose vascular receptors were active. Those 7 patients wer... | [Correction of the alphamimetic effects of metaraminol by nicergoline]. In this work, the authors are studying the cardio-vascular effects of nicergoline. To do so, the drug is made to compete with metaraminol whose dominant alphamimetic effects are known. This experimentation was performed in 7 patients in coma stage ... | [
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PMID:15482 | [Continuous measurement of arterial pressure by means of an arterial catheter. Its value in secondary transport]. | It is of no much use to try to assess the cardiovascular condition of patients with impending or confirmed shock by taking the blood pressure with the classical arm cuff, especially if arterfacts such as noise, vibrations, shaking etc... are interfering. Instant continuous measurement of blood pressure by means of arte... | [Continuous measurement of arterial pressure by means of an arterial catheter. Its value in secondary transport]. It is of no much use to try to assess the cardiovascular condition of patients with impending or confirmed shock by taking the blood pressure with the classical arm cuff, especially if arterfacts such as no... | [
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PMID:15484 | [Use of constant perithoracic negative pressure in the transport of newborn infants with severe forms of idiopathic respiratory distress]. | The authors used for transportation of neonates in severe idiopathic respiratory distress the continuous perithoracic negative pressure method suggested by OUTBRIGE and STERN in neonate intensive care. The authors are describing the material used and are presenting their first encouraging results. This technique improv... | [Use of constant perithoracic negative pressure in the transport of newborn infants with severe forms of idiopathic respiratory distress]. The authors used for transportation of neonates in severe idiopathic respiratory distress the continuous perithoracic negative pressure method suggested by OUTBRIGE and STERN in neo... | [
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PMID:15485 | [Do enzyme determinations have any prognostic value in neurotraumatology?]. | In 34 cases of skull traumas and in 14 cases of acute cerebral accidents, CK, GOT, GPT, LDH and its isoenzymes were assessed in the patient's serum and CSF. Results show that the increase of the enzymatic level in the CSF seems due to cerebral tissue damage for the main part, when in the serum the increase is influence... | [Do enzyme determinations have any prognostic value in neurotraumatology?]. In 34 cases of skull traumas and in 14 cases of acute cerebral accidents, CK, GOT, GPT, LDH and its isoenzymes were assessed in the patient's serum and CSF. Results show that the increase of the enzymatic level in the CSF seems due to cerebral ... | [
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PMID:15486 | [Value of cerebral metabolic exploration in post-traumatic coma states in the acute phase]. | The authors report the values of mean hemispheric blood-flow and cerebral arterial consumption they found in 34 neurosurgical comatous cases in acute state. In basal conditions, mean values of mean hemispheric bloodflow and oxygen consumption are lowered. There seems to be a relation between the values found and the co... | [Value of cerebral metabolic exploration in post-traumatic coma states in the acute phase]. The authors report the values of mean hemispheric blood-flow and cerebral arterial consumption they found in 34 neurosurgical comatous cases in acute state. In basal conditions, mean values of mean hemispheric bloodflow and oxyg... | [
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PMID:15487 | Characteristics of two new reticuloendotheliosis virus isolates of turkeys. | Reticuloendotheliosis (RE) virus strains MN81 and MN67 isolated from epiornithics of RE in turkeys were partially characterized. Strains MN81 and MN67 replicated in chicken embryo fibroblast,duck embryo fibroblast and turkey embryo-fibroblast cultures and produced syncytial cytopathic effects in duck embryo fibroblast ... | Characteristics of two new reticuloendotheliosis virus isolates of turkeys. Reticuloendotheliosis (RE) virus strains MN81 and MN67 isolated from epiornithics of RE in turkeys were partially characterized. Strains MN81 and MN67 replicated in chicken embryo fibroblast,duck embryo fibroblast and turkey embryo-fibroblast c... | [
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PMID:15488 | Body position and mode of ventilation influences arterial pH, oxygen, and carbon dioxide tensions in halothane-anesthetized horses. | Effects of body position and type of ventilation were determined on arterial blood gases (PaO2, PaCO2) and pH during and immediately following clinical halothane anesthesia in 36 young, physically conditioned horses. Horses in dorsal recumbency had a lower PaO2 than did similarly breathing horses in a lateral position.... | Body position and mode of ventilation influences arterial pH, oxygen, and carbon dioxide tensions in halothane-anesthetized horses. Effects of body position and type of ventilation were determined on arterial blood gases (PaO2, PaCO2) and pH during and immediately following clinical halothane anesthesia in 36 young, ph... | [
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PMID:15489 | Effects of electroanesthesia and a phenothiazine tranquilizer on thermoregulation in the sheep. | The effects of giving propiopromazine alone and of electroanesthesia-propiopromazine treatment on thermoregulation (body temperature regulation) were studied in 3 sheep at ambient temperatures of 5, 25, and 35 C. Measures of thermoregulation during a 120-minute treatment and 120-treatment recovery period included recta... | Effects of electroanesthesia and a phenothiazine tranquilizer on thermoregulation in the sheep. The effects of giving propiopromazine alone and of electroanesthesia-propiopromazine treatment on thermoregulation (body temperature regulation) were studied in 3 sheep at ambient temperatures of 5, 25, and 35 C. Measures of... | [
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PMID:15490 | Microimmunodiffusion test for detection of antibodies to infectious bovine rhinotracheitis virus in bovine serum. | A microimmunodiffusion test (MIDT) specific for detection of antibodies to infectious bovine rhinotracheitis (IBR) in bovine serum has been developed. The antigen used in the MIDT was prepared from IBR virus-infected Madin-Darby bovine kidney cells grown in tissue culture. The antigen was stable, and relatively high yi... | Microimmunodiffusion test for detection of antibodies to infectious bovine rhinotracheitis virus in bovine serum. A microimmunodiffusion test (MIDT) specific for detection of antibodies to infectious bovine rhinotracheitis (IBR) in bovine serum has been developed. The antigen used in the MIDT was prepared from IBR viru... | [
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PMID:15491 | The syndrome of inappropriate secretion of antidiuretic hormone associated with anaerobic thoracic empyema. | The syndrome of inappropriate secretion of antidiuretic hormone has been associated with many pulmonary diseases, including tuberculosis and bacterial and viral pneumonia: however, it has not been reported with anaerobic infections or empyema in the absence of pneumonia. We report a patient with empyema due to Bacteroi... | The syndrome of inappropriate secretion of antidiuretic hormone associated with anaerobic thoracic empyema. The syndrome of inappropriate secretion of antidiuretic hormone has been associated with many pulmonary diseases, including tuberculosis and bacterial and viral pneumonia: however, it has not been reported with a... | [
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PMID:15492 | [Study on L-malic acid catabolism by "Lactobacillus casei" cells immobilized into polyacrylamide gel lattice (author's transl)]. | Study on L-malic acid catabolism by Lactobacillus casei cells immobilized into polyacrylamide gel lattice has shown that the pH profil of malic acid decarboxylase activity does not differ significantly from that of free cells. The apparent enzymatic constant value as determined by the Warburg manometric method is 5 X 1... | [Study on L-malic acid catabolism by "Lactobacillus casei" cells immobilized into polyacrylamide gel lattice (author's transl)]. Study on L-malic acid catabolism by Lactobacillus casei cells immobilized into polyacrylamide gel lattice has shown that the pH profil of malic acid decarboxylase activity does not differ sig... | [
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PMID:15494 | [Cross reactions of higher type-specific capsular polysaccharides of Klebsiella in antipneumococcal sera]. | Qualitative and quantitative precipitin reactions are given of the polysaccharides K60, K61, K65, K67-69, K70, K71, K73, and K83, also of depyruvylated K1. As expected, the last reacts more strongly in antipneumococcal (anti-Pn) VIII and X than does intact K1. K65 and K67 precipitate much of the same large fraction of ... | [Cross reactions of higher type-specific capsular polysaccharides of Klebsiella in antipneumococcal sera]. Qualitative and quantitative precipitin reactions are given of the polysaccharides K60, K61, K65, K67-69, K70, K71, K73, and K83, also of depyruvylated K1. As expected, the last reacts more strongly in antipneumoc... | [
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0.020668331533670425,
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-... |
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