id int64 225 5.32k | context stringlengths 2.88k 70.8k | question stringlengths 11 194 | answers dict | is_impossible bool 1
class |
|---|---|---|---|---|
3,252 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | How long did it take for patients with positive human adenovirus type 55 (HAdV-55) endotracheal aspirates to develop a measurable viremia? | {
"answer_start": [
10911
],
"text": [
"1 to 10 days"
]
} | false |
3,253 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | Does blood type play a role in the severity of human adenovirus type 55 (HAdV-55) infection? | {
"answer_start": [
12906
],
"text": [
" HAdV-55 may cause severe ARDS in immunocompetent young men with blood type B"
]
} | false |
3,254 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | What are the most common clinical manifestations of severe human adenovirus type 55 (HAdV-55) induced ARDS? | {
"answer_start": [
13068
],
"text": [
"Persistent high fever, dyspnea and rapid progression to respiratory failure within 2 weeks, together with bilateral consolidations and infiltrates at the same time, are the most frequent clinical manifestations"
]
} | false |
3,255 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | What is the mortality rate of severe ARDS from human adenovirus type 55 (HAdV-55)? | {
"answer_start": [
13514
],
"text": [
"HAdV-55-induced severe ARDS has a very high mortality rate (80%) despite appropriate respiratory support."
]
} | false |
3,256 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | What role does T-cell count play in severe human adenovirus type 55 (HAdV-55) infection? | {
"answer_start": [
15873
],
"text": [
"a lower T-cell count may be a risk factor for HAdV-55 infection in young adults"
]
} | false |
3,257 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | How successful are the use of invasive mechanical ventilation (IMV) and non-invasive positive pressure ventilation (NPPV) in the treatment of severe ARDS from human adenovirus type 55 infection? | {
"answer_start": [
16491
],
"text": [
"we found that severe HAdV-55 infection could cause a rapid progression of respiratory failure, with a very high failure rate for NPPV and IMV"
]
} | false |
5,252 | Diagnostic accuracy of C-reactive protein and procalcitonin in suspected community-acquired pneumonia adults visiting emergency department and having a systematic thoracic CT scan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608327/
SHA: f3d150545162ff3cc253c235011a02a91ee676cb
Authors: Le Bel, Josselin; Hausfater,... | How many patients were analyzed in the study? | {
"answer_start": [
1521
],
"text": [
"Two hundred"
]
} | false |
5,253 | Diagnostic accuracy of C-reactive protein and procalcitonin in suspected community-acquired pneumonia adults visiting emergency department and having a systematic thoracic CT scan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608327/
SHA: f3d150545162ff3cc253c235011a02a91ee676cb
Authors: Le Bel, Josselin; Hausfater,... | How many patients with community-acquired pneumonia are hospitalized each year? | {
"answer_start": [
3121
],
"text": [
"600,000"
]
} | false |
5,254 | Diagnostic accuracy of C-reactive protein and procalcitonin in suspected community-acquired pneumonia adults visiting emergency department and having a systematic thoracic CT scan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608327/
SHA: f3d150545162ff3cc253c235011a02a91ee676cb
Authors: Le Bel, Josselin; Hausfater,... | What chest X-ray findings are typically indicative of community-acquired pneumonia? | {
"answer_start": [
3577
],
"text": [
"the presence of new parenchymal infiltrates"
]
} | false |
5,256 | Pandemic Influenza Due to pH1N1/2009 Virus: Estimation of Infection Burden in Reunion Island through a Prospective Serosurvey, Austral Winter 2009
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183080/
SHA: ee6d70a53e3262cea6f85bd8b226f6b4c8b5f64b
Authors: Dellagi, Koussay; Rollot, Olivier; Temmam, Sarah; Salez, Nico... | When did WHO declare a pandemic of pH1N1/2009v influenza? | {
"answer_start": [
2887
],
"text": [
"11 June 2009"
]
} | false |
5,257 | Pandemic Influenza Due to pH1N1/2009 Virus: Estimation of Infection Burden in Reunion Island through a Prospective Serosurvey, Austral Winter 2009
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183080/
SHA: ee6d70a53e3262cea6f85bd8b226f6b4c8b5f64b
Authors: Dellagi, Koussay; Rollot, Olivier; Temmam, Sarah; Salez, Nico... | What is the classical cutoff value for antibody titers? | {
"answer_start": [
22699
],
"text": [
"1/40"
]
} | false |
5,258 | Pandemic Influenza Due to pH1N1/2009 Virus: Estimation of Infection Burden in Reunion Island through a Prospective Serosurvey, Austral Winter 2009
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183080/
SHA: ee6d70a53e3262cea6f85bd8b226f6b4c8b5f64b
Authors: Dellagi, Koussay; Rollot, Olivier; Temmam, Sarah; Salez, Nico... | What is meant by a protective HIA titer? | {
"answer_start": [
22786
],
"text": [
"conferring 50% protection against a viral challenge"
]
} | false |
5,259 | Pandemic Influenza Due to pH1N1/2009 Virus: Estimation of Infection Burden in Reunion Island through a Prospective Serosurvey, Austral Winter 2009
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183080/
SHA: ee6d70a53e3262cea6f85bd8b226f6b4c8b5f64b
Authors: Dellagi, Koussay; Rollot, Olivier; Temmam, Sarah; Salez, Nico... | What are the results of the study? | {
"answer_start": [
24962
],
"text": [
"a substantial proportion of Reunion Island's population had pre-existing immunity to 2009 pandemic influenza virus"
]
} | false |
5,260 | Pandemic Influenza Due to pH1N1/2009 Virus: Estimation of Infection Burden in Reunion Island through a Prospective Serosurvey, Austral Winter 2009
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183080/
SHA: ee6d70a53e3262cea6f85bd8b226f6b4c8b5f64b
Authors: Dellagi, Koussay; Rollot, Olivier; Temmam, Sarah; Salez, Nico... | What was the interpretation for the crossreactive antibodies? | {
"answer_start": [
25486
],
"text": [
"the remote exposure of these individuals to H1N1 viruses circulating before 1957"
]
} | false |
5,261 | Pandemic Influenza Due to pH1N1/2009 Virus: Estimation of Infection Burden in Reunion Island through a Prospective Serosurvey, Austral Winter 2009
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183080/
SHA: ee6d70a53e3262cea6f85bd8b226f6b4c8b5f64b
Authors: Dellagi, Koussay; Rollot, Olivier; Temmam, Sarah; Salez, Nico... | How long did the pH1N1/2009 viral outbreak last? | {
"answer_start": [
28239
],
"text": [
"9 weeks"
]
} | false |
5,262 | High Burden of Non-Influenza Viruses in Influenza-Like Illness in the Early Weeks of H1N1v Epidemic in France
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157400/
SHA: f4c1afe385e9e31eb5678e15a3c280ba97326554
Authors: Schnepf, Nathalie; Resche-Rigon, Matthieu; Chaillon, Antoine; Scemla, Anne; Gras, Guillaume; Semou... | What were the aims of this study? | {
"answer_start": [
1012
],
"text": [
"to investigate the different pathogens involved in ILI and describe the associated symptoms"
]
} | false |
5,263 | High Burden of Non-Influenza Viruses in Influenza-Like Illness in the Early Weeks of H1N1v Epidemic in France
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157400/
SHA: f4c1afe385e9e31eb5678e15a3c280ba97326554
Authors: Schnepf, Nathalie; Resche-Rigon, Matthieu; Chaillon, Antoine; Scemla, Anne; Gras, Guillaume; Semou... | What network of physicians provides real-time clinical data on the spread of influenza in France? | {
"answer_start": [
2654
],
"text": [
"Réseau Sentinelles"
]
} | false |
5,264 | High Burden of Non-Influenza Viruses in Influenza-Like Illness in the Early Weeks of H1N1v Epidemic in France
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157400/
SHA: f4c1afe385e9e31eb5678e15a3c280ba97326554
Authors: Schnepf, Nathalie; Resche-Rigon, Matthieu; Chaillon, Antoine; Scemla, Anne; Gras, Guillaume; Semou... | What are the criteria used to define an influenza-like illness in France? | {
"answer_start": [
2913
],
"text": [
"a sudden fever above 39uC with myalgia and respiratory signs"
]
} | false |
5,265 | High Burden of Non-Influenza Viruses in Influenza-Like Illness in the Early Weeks of H1N1v Epidemic in France
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157400/
SHA: f4c1afe385e9e31eb5678e15a3c280ba97326554
Authors: Schnepf, Nathalie; Resche-Rigon, Matthieu; Chaillon, Antoine; Scemla, Anne; Gras, Guillaume; Semou... | What virus was the most common among the H1N1v negative patients? | {
"answer_start": [
11928
],
"text": [
"rhinovirus"
]
} | false |
5,269 | Livestock Drugs and Disease: The Fatal Combination behind Breeding Failure in Endangered Bearded Vultures
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994777/
SHA: f4f804bac7b32c84ad6572776df684df2a2e5fda
Authors: Blanco, Guillermo; Lemus, Jesús A.
Date: 2010-11-30
DOI: 10.1371/journal.pone.0014163
License: cc-by
... | What was the aim of this study? | {
"answer_start": [
662
],
"text": [
"to elucidate the proximate causes of breeding failure behind the recent decline in productivity in the Spanish Pyrenees"
]
} | false |
5,270 | Livestock Drugs and Disease: The Fatal Combination behind Breeding Failure in Endangered Bearded Vultures
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994777/
SHA: f4f804bac7b32c84ad6572776df684df2a2e5fda
Authors: Blanco, Guillermo; Lemus, Jesús A.
Date: 2010-11-30
DOI: 10.1371/journal.pone.0014163
License: cc-by
... | Where is the bearded vulture (Gypaetus barbatus) commonly found? | {
"answer_start": [
3127
],
"text": [
"the Pyrenees"
]
} | false |
5,277 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What was the focus of this study? | {
"answer_start": [
856
],
"text": [
"the antiproliferative effect of a copper (II) complex on HT-29 colon cancer cells"
]
} | false |
5,278 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What is the third most prevalent cancer in females in the United States? | {
"answer_start": [
2187
],
"text": [
"colorectal cancer"
]
} | false |
5,279 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What is the 1-year survival rate for colorectal cancer patients? | {
"answer_start": [
2537
],
"text": [
"83.2%"
]
} | false |
5,280 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What is the 5-year survival rate for colorectal cancer patients? | {
"answer_start": [
2547
],
"text": [
"64.3%"
]
} | false |
5,281 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | How were nuclear morphological changes in HT-29 cells measured? | {
"answer_start": [
16150
],
"text": [
"detection of nuclear condensation"
]
} | false |
5,282 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What is directly related to nuclear condensation? | {
"answer_start": [
16300
],
"text": [
"apoptotic chromatin changes"
]
} | false |
5,283 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What morphological cell changes are most associated with apoptosis? | {
"answer_start": [
18570
],
"text": [
"membrane permeability, cell shrinkage, disruption of the mitochondrial membrane, and chromatin condensation"
]
} | false |
5,284 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What types of cells are suitable for colon cancer studies? | {
"answer_start": [
19277
],
"text": [
"HT-29 cells"
]
} | false |
5,285 | Multivalent HA DNA Vaccination Protects against Highly Pathogenic H5N1 Avian Influenza Infection in Chickens and Mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657001/
SHA: ef872b80cf38917f64c42bfa52a57beb4399897a
Authors: Rao, Srinivas; Kong, Wing-Pui; Wei, Chih-Jen; Yang, Zhi-Yong; Nason, Martha; Styles, Darre... | What was the goal of this study? | {
"answer_start": [
5812
],
"text": [
"to explore the feasibility of DNA vaccination of poultry"
]
} | false |
5,286 | Multivalent HA DNA Vaccination Protects against Highly Pathogenic H5N1 Avian Influenza Infection in Chickens and Mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657001/
SHA: ef872b80cf38917f64c42bfa52a57beb4399897a
Authors: Rao, Srinivas; Kong, Wing-Pui; Wei, Chih-Jen; Yang, Zhi-Yong; Nason, Martha; Styles, Darre... | What is the conclusion of this study? | {
"answer_start": [
6165
],
"text": [
"it is possible to develop a multivalent DNA vaccine for poultry that can protect against multiple HPAI H5N1 strains and that could keep pace with the continued evolution of avian influenza viruses"
]
} | false |
5,298 | Metabolic engineering of Escherichia coli into a versatile glycosylation platform: production of bio-active quercetin glycosides
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573293/
SHA: f4cd52975e6aa33e8c947082eda9b261952b0f8f
Authors: De Bruyn, Frederik; Van Brempt, Maarten; Maertens, Jo; Van Bellegem, Wouter; Du... | What was the conclusion of this study? | {
"answer_start": [
2016
],
"text": [
"Two E. coli W mutants were engineered that could effectively produce the bio-active flavonol glycosides hyperoside and quercitrin"
]
} | false |
5,299 | Metabolic engineering of Escherichia coli into a versatile glycosylation platform: production of bio-active quercetin glycosides
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573293/
SHA: f4cd52975e6aa33e8c947082eda9b261952b0f8f
Authors: De Bruyn, Frederik; Van Brempt, Maarten; Maertens, Jo; Van Bellegem, Wouter; Du... | What are the implications of the novel fermentation-based glycosylation strategy described in this study? | {
"answer_start": [
2268
],
"text": [
"the economically viable production of various glycosides"
]
} | false |
5,300 | Metabolic engineering of Escherichia coli into a versatile glycosylation platform: production of bio-active quercetin glycosides
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573293/
SHA: f4cd52975e6aa33e8c947082eda9b261952b0f8f
Authors: De Bruyn, Frederik; Van Brempt, Maarten; Maertens, Jo; Van Bellegem, Wouter; Du... | What characteristics does glycosylation have on flavonoids? | {
"answer_start": [
3403
],
"text": [
"solubility, stability and bio-activity"
]
} | false |
5,292 | Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300492/
SHA: f0c2cd2793d71f1ea11a810442a2c06d5013e899
Authors: Yu, Haijing; Liu, Yang; Wang, Hongwu; Wan, Xiaoyang; Huang, ... | What is fibrinogen-like protein 2 (FgI2)? | {
"answer_start": [
748
],
"text": [
"a pro-coagulant protein"
]
} | false |
5,293 | Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300492/
SHA: f0c2cd2793d71f1ea11a810442a2c06d5013e899
Authors: Yu, Haijing; Liu, Yang; Wang, Hongwu; Wan, Xiaoyang; Huang, ... | What represses murine hepatitis virus strain 3 (MHV-3) infection? | {
"answer_start": [
843
],
"text": [
"Fgl2 depletion"
]
} | false |
5,294 | Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300492/
SHA: f0c2cd2793d71f1ea11a810442a2c06d5013e899
Authors: Yu, Haijing; Liu, Yang; Wang, Hongwu; Wan, Xiaoyang; Huang, ... | What was the goal of this study? | {
"answer_start": [
1157
],
"text": [
"to determine the role of CC10 in FH and the regulation of Fgl2 by CC10"
]
} | false |
5,295 | Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300492/
SHA: f0c2cd2793d71f1ea11a810442a2c06d5013e899
Authors: Yu, Haijing; Liu, Yang; Wang, Hongwu; Wan, Xiaoyang; Huang, ... | What is fulminant hepatitis? | {
"answer_start": [
2830
],
"text": [
"a serious life-threatening disease characterized by massive hepatocyte necrosis"
]
} | false |
5,296 | Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300492/
SHA: f0c2cd2793d71f1ea11a810442a2c06d5013e899
Authors: Yu, Haijing; Liu, Yang; Wang, Hongwu; Wan, Xiaoyang; Huang, ... | How does Prothrombinase Fgl2 affect the coagulation process? | {
"answer_start": [
3792
],
"text": [
"transforming prothrombin directly into thrombin,"
]
} | false |
5,297 | Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300492/
SHA: f0c2cd2793d71f1ea11a810442a2c06d5013e899
Authors: Yu, Haijing; Liu, Yang; Wang, Hongwu; Wan, Xiaoyang; Huang, ... | How long after MHV-3 infection were liver samples taken? | {
"answer_start": [
19631
],
"text": [
"72 h"
]
} | false |
585 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the relationship between urbanization and risk of emergence of flu-like diseases? | {
"answer_start": [
1274
],
"text": [
" findings suggest that urbanization spatially combines risk factors to produce particular types of peri-urban landscapes with significantly higher HPAI H5N1 emergence risk."
]
} | false |
586 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What factors and characteristics of semi-urban landscapes promote viral transmission? | {
"answer_start": [
1505
],
"text": [
" higher levels of chicken densities, duck and geese flock size diversities, and fraction of land under rice or aquaculture than rural and urban areas. We also found that land-use diversity, a surrogate measure for potential mixing of host populations and other factor... | false |
587 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the relationship between HIN1 viral transmission and poultry production. | {
"answer_start": [
1877
],
"text": [
" landscapes where intensive and extensive forms of poultry production overlap were found at greater risk"
]
} | false |
588 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the principle behind infection Convergence Model ? | {
"answer_start": [
4614
],
"text": [
"The convergence model can be so adapted by incorporating the dynamics of urban, agricultural, and natural ecosystem transformations proposed with this framework. These associated multifaceted interactions including feedbacks that affect ecological communities, hosts ... | false |
590 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the Boosted Regression Tree method? | {
"answer_start": [
25944
],
"text": [
"BRT utilizes regression trees and boosting algorithms to fit several models and combines them for improving prediction by performing iterative loop throughout the model "
]
} | false |
591 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the advantage of Boosted Regression Tree method? | {
"answer_start": [
26125
],
"text": [
"The advantage of BRT is that it applies stochastic processes that include probabilistic components to improve predictive performance."
]
} | false |
592 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the relationship between land use and emergence of HPAI H5N1? | {
"answer_start": [
34261
],
"text": [
" high land-use diversity landscapes, a variable not previously considered in spatial studies of HPAI H5N1, are at significantly greater risk for HPAI H5N1 outbreaks"
]
} | false |
589 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | Where is the highest risk of HPAI H5N1 like disease emergence? | {
"answer_start": [
5073
],
"text": [
"Emergence risk should be highest in the most rapidly transforming urban areas, peri-urban zones where mixes of urban-rural, modern-traditional land uses and poultry husbandry coincide most intensely."
]
} | false |
594 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | How does land use fragmentation increase the risk of flu-like diseases? | {
"answer_start": [
11013
],
"text": [
"Landscape fragmentation produces ecotones, defined as abrupt edges or transitions zones between different ecological systems, thought to facilitate disease emergence by increasing the intensity and frequency of contact between host species [31] Furthermore, fragment... | false |
596 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the relationship between the outbreak of HPAI H5N1 like diseases and rice cultivation? | {
"answer_start": [
16923
],
"text": [
" extent of rice cultivation is a risk factor, mainly due its association with free ranging ducks acting as scavengers"
]
} | false |
597 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the relationship between aquaculture and spread of H5N1 like diseases? | {
"answer_start": [
17269
],
"text": [
"extent of aquaculture is a known risk factor [10] , possibly because water bodies offer routes for transmission and persistence of the virus"
]
} | false |
598 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the relationship between proximity ofwater bodies to agricultural lands and spread of H5N1 like diseases? | {
"answer_start": [
17475
],
"text": [
"Proximity to water bodies increases the risk of outbreaks [47, [50] [51] [52] , possibly by increasing the chance of contact between wild water birds and domestic poultry."
]
} | false |
599 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is the effect of diversity of chicken flock on H5N1 disease? | {
"answer_start": [
31106
],
"text": [
"diversity of chicken flock-size had a strong association with HPAI H5N1 "
]
} | false |
600 | Evidence for the Convergence Model: The Emergence of Highly Pathogenic Avian Influenza (H5N1) in Viet Nam
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580613/
SHA: ee5b43d20a640664510cb7a540caaae4a8e19933
Authors: Saksena, Sumeet; Fox, Jefferson; Epprecht, Michael; Tran, Chinh C.; Nong, Duong H.; Spencer, James H.;... | What is Compound Topological Index and how is it related to the risk of disease transmission? | {
"answer_start": [
18005
],
"text": [
"Compound Topographical Index (CTI, also known as Topographical Wetness Index) is a measure of the tendency for water to pool. Studies in Thailand and elsewhere [54] have shown that the extent of surface water is a strong risk factor, possibly due to the role of wate... | false |
655 | Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078228/
SHA: 1cf54d1c77b7f0494ab971429d26e0e199952d09
Authors: Liu, Jia; Cao, Ruiyuan; Xu, Mingyue; Wang, Xi; Zhang, Huanyu; Hu, Hengrui; Li, Yufeng; Hu, ... | In vitro comparison of antiviral activity of Chloroquine(CQ) and Hydroxychloroquine(HCQ) against COVID-19? | {
"answer_start": [
4794
],
"text": [
"compare the antiviral activity of CQ versus HCQ, the dose-response curves"
]
} | false |
651 | Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078228/
SHA: 1cf54d1c77b7f0494ab971429d26e0e199952d09
Authors: Liu, Jia; Cao, Ruiyuan; Xu, Mingyue; Wang, Xi; Zhang, Huanyu; Hu, Hengrui; Li, Yufeng; Hu, ... | What will be the drug of choice for treating COVID-19 between Chloroquine and Remdesivir? | {
"answer_start": [
1897
],
"text": [
" two potential drugs, CQ appears to be the drug of choice for large-scale use due to its availability, proven safety record, and a relatively low cost."
]
} | false |
658 | Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078228/
SHA: 1cf54d1c77b7f0494ab971429d26e0e199952d09
Authors: Liu, Jia; Cao, Ruiyuan; Xu, Mingyue; Wang, Xi; Zhang, Huanyu; Hu, Hengrui; Li, Yufeng; Hu, ... | Mechanism of action of Chloroquine(CQ) and Hydroxychloroquine(HCQ) against COVID-19? | {
"answer_start": [
6327
],
"text": [
"CQ and HCQ are weak bases that are known to elevate the pH of acidic intracellular organelles"
]
} | false |
661 | Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078228/
SHA: 1cf54d1c77b7f0494ab971429d26e0e199952d09
Authors: Liu, Jia; Cao, Ruiyuan; Xu, Mingyue; Wang, Xi; Zhang, Huanyu; Hu, Hengrui; Li, Yufeng; Hu, ... | What is the effect of Chloroquine(CQ) and Hydroxychloroquine(HCQ) on endosomal maturation and endocytosis in COVID-19 treatment? | {
"answer_start": [
8734
],
"text": [
"Since acidification is crucial for endosome maturation and function, we surmise that endosome maturation might be blocked at intermediate stages of endocytosis,"
]
} | false |
662 | Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078228/
SHA: 1cf54d1c77b7f0494ab971429d26e0e199952d09
Authors: Liu, Jia; Cao, Ruiyuan; Xu, Mingyue; Wang, Xi; Zhang, Huanyu; Hu, Hengrui; Li, Yufeng; Hu, ... | Evidence of Hydroxychloroquine(HCQ) being anti inflammatory in SARS-CoV-2 critically ill patients with elevated plasma cytokines? | {
"answer_start": [
11799
],
"text": [
" HCQ is a safe and successful anti-inflammatory agent"
]
} | false |
3,459 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What proportion of healthcare workers reported symptoms of depression? | {
"answer_start": [
2058
],
"text": [
"50.4%"
]
} | false |
3,460 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What proportion of healthcare workers reported symptoms of anxiety? | {
"answer_start": [
2080
],
"text": [
"[44.6%"
]
} | false |
3,461 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What proportion of healthcare workers reported symptoms of insomnia? | {
"answer_start": [
2105
],
"text": [
"34.0%"
]
} | false |
3,462 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What proportion reported distress? | {
"answer_start": [
2132
],
"text": [
"[71.5%"
]
} | false |
3,463 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What were the Generalized Anxiety Disorder scale scores? | {
"answer_start": [
2530
],
"text": [
"among men vs women: 2.0 [0-6.0] vs 4.0 [1.0-7.0]; P < .001"
]
} | false |
3,464 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What were the Insomnia Severity Index scores ? | {
"answer_start": [
2634
],
"text": [
"among frontline vs second-line workers: 6.0 [2.0-11.0] vs 4.0 [1.0-8.0]; P < .001"
]
} | false |
3,465 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What were the Impact of Event Scale–Revised scores? | {
"answer_start": [
2844
],
"text": [
" 21.0 [8.5-34.5] vs 18.0 [6.0-28.0] in Hubei outside Wuhan and 15.0 [4.0-26.0] outside Hubei; P < .001)."
]
} | false |
3,466 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What were the results of analysis? | {
"answer_start": [
2999
],
"text": [
"participants from outside Hubei province were associated with lower risk of experiencing symptoms of distress compared with those in Wuhan (odds ratio [OR], 0.62; 95% CI, 0.43-0.88; P = .008)"
]
} | false |
3,467 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What were the results of analysis? | {
"answer_start": [
3192
],
"text": [
"Frontline health care workers engaged in direct diagnosis, treatment, and care of patients with COVID-19 were associated with a higher risk of symptoms of depression (OR, 1.52; 95% CI, 1.11-2.09; P = .01), anxiety (OR, 1.57; 95% CI, 1.22-2.02; P < .001), insomnia (OR... | false |
3,468 | Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090843/
SHA: 0a08fddd9dcee1b1254a05b49113521bbc423ccd
Authors: Lai, Jianbo; Ma, Simeng; Wang, Ying; Cai, Zhongxiang; Hu, Jianbo; Wei, Ning; Wu, Jiang; Du, Hui; Ch... | What are the conclusions of this study? | {
"answer_start": [
3578
],
"text": [
"In this survey of heath care workers in hospitals equipped with fever clinics or wards for patients with COVID-19 in Wuhan and other regions in China, participants reported experiencing psychological burden, especially nurses, women, those in Wuhan, and frontline hea... | false |
924 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What are microtubule severing enzymes? | {
"answer_start": [
2018
],
"text": [
"a family of AAA-ATPase proteins"
]
} | false |
926 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What genetic mutation is associated with hereditary spastic paraplegia? | {
"answer_start": [
2332
],
"text": [
"SPG4"
]
} | false |
927 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What genetic mutation is associated with cerebral malformations? | {
"answer_start": [
2338
],
"text": [
"KATNB1"
]
} | false |
928 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What genetic mutation is associated with autism? | {
"answer_start": [
2349
],
"text": [
"KATNAL2"
]
} | false |
929 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What is KATNAL1? | {
"answer_start": [
2548
],
"text": [
"microtubule severing enzyme"
]
} | false |
930 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What organ is most associated with the KATNAL1 gene? | {
"answer_start": [
3332
],
"text": [
"central nervous system"
]
} | false |
931 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What CNS functions can be measured by studying the movement of mice in a T-maze? | {
"answer_start": [
11976
],
"text": [
"working memory and spatial memory"
]
} | false |
932 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What CNS functions are changed by mutations in the KATNAL1 gene? | {
"answer_start": [
20200
],
"text": [
"circadian rhythms, sleep and behaviour"
]
} | false |
1,220 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | How is Japanese encephalitis transmitted? | {
"answer_start": [
395
],
"text": [
"arthropod"
]
} | false |
1,222 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What element is essential to promoting JEV infection? | {
"answer_start": [
1085
],
"text": [
"calcium"
]
} | false |
1,223 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | Where is Q130 located in the NS4B protein? | {
"answer_start": [
1250
],
"text": [
"transmembrane domain 3"
]
} | false |
1,224 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What is the mechanism of action for manidipine? | {
"answer_start": [
1409
],
"text": [
"voltage-gated Ca(2+) channel (VGCC) inhibitor"
]
} | false |
1,225 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | How many different pathogens are members of the Flaviviridae family of virus? | {
"answer_start": [
2672
],
"text": [
"70"
]
} | false |
1,226 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What is the size of a flavivirus? | {
"answer_start": [
3311
],
"text": [
"11-kb"
]
} | false |
1,227 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | How many open reading frames are in the flavivirus genome? | {
"answer_start": [
3359
],
"text": [
"single"
]
} | false |
1,228 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What are the structural protein elements of a flavivirus? | {
"answer_start": [
3504
],
"text": [
"capsid (C), membrane (premembrane [prM] and membrane [M] ), and envelope (E)"
]
} | false |
1,229 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What is the function of the nonstructural protein elements of the flavivirus? | {
"answer_start": [
3715
],
"text": [
"viral replication, virion assembly, and virus escape from immune surveillance."
]
} | false |
1,230 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What are RVPs? | {
"answer_start": [
4380
],
"text": [
"Recombinant viral particles"
]
} | false |
1,231 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What is HTS? | {
"answer_start": [
4596
],
"text": [
"high-throughput screening"
]
} | false |
1,232 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What is the selective index in high throughput screening? | {
"answer_start": [
5400
],
"text": [
"the 50% cytotoxic concentration"
]
} | false |
1,233 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What is the structure of a recombiant viral particle? | {
"answer_start": [
7484
],
"text": [
"a natural virus-like envelope on the outside and a replicon on the inside"
]
} | false |
1,234 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640845/
SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What measure is used in high-throughput screening to identify potential antiviral compounds? | {
"answer_start": [
812
],
"text": [
"selective index of >10"
]
} | false |
430 | Rotavirus A in wild and domestic animals from areas with environmental degradation in the Brazilian Amazon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298726/
SHA: f3c309c596c20f48f493b77e714ce957d877bdcb
Authors: de Barros, Bruno de Cássio Veloso; Chagas, Elaine Nunes; Bezerra, Luna Wanessa; Ribeiro, Laila Grazie... | How many known species of Rotavirus exist? | {
"answer_start": [
3868
],
"text": [
"nine species"
]
} | false |
431 | Rotavirus A in wild and domestic animals from areas with environmental degradation in the Brazilian Amazon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298726/
SHA: f3c309c596c20f48f493b77e714ce957d877bdcb
Authors: de Barros, Bruno de Cássio Veloso; Chagas, Elaine Nunes; Bezerra, Luna Wanessa; Ribeiro, Laila Grazie... | Is Rotavirus single or double-stranded? | {
"answer_start": [
4111
],
"text": [
"double-stranded ribonucleic acid"
]
} | false |
432 | Rotavirus A in wild and domestic animals from areas with environmental degradation in the Brazilian Amazon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298726/
SHA: f3c309c596c20f48f493b77e714ce957d877bdcb
Authors: de Barros, Bruno de Cássio Veloso; Chagas, Elaine Nunes; Bezerra, Luna Wanessa; Ribeiro, Laila Grazie... | What structural proteins are coded by Rotavirus? | {
"answer_start": [
4217
],
"text": [
"VP1-VP4, VP6 and VP7"
]
} | false |
433 | Rotavirus A in wild and domestic animals from areas with environmental degradation in the Brazilian Amazon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298726/
SHA: f3c309c596c20f48f493b77e714ce957d877bdcb
Authors: de Barros, Bruno de Cássio Veloso; Chagas, Elaine Nunes; Bezerra, Luna Wanessa; Ribeiro, Laila Grazie... | What non-structural proteins are coded by Rotavirus? | {
"answer_start": [
4258
],
"text": [
"NSP1-NSP5/NSP6"
]
} | false |
434 | Rotavirus A in wild and domestic animals from areas with environmental degradation in the Brazilian Amazon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298726/
SHA: f3c309c596c20f48f493b77e714ce957d877bdcb
Authors: de Barros, Bruno de Cássio Veloso; Chagas, Elaine Nunes; Bezerra, Luna Wanessa; Ribeiro, Laila Grazie... | What is qRT-PCR? | {
"answer_start": [
6347
],
"text": [
"qualitative real-time polymerase chain reaction"
]
} | false |
4,255 | Regulation and Maintenance of an Adoptive T-Cell Dependent Memory B Cell Pool
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120830/
SHA: f4a82ad66962355ffb09e4d1b57fde3e94f0ec53
Authors: Anson, Marie; Amado, Inês; Mailhé, Marie-Pierre; Donnadieu, Emmanuel; Garcia, Sylvie; Huetz, François; Freitas, Antonio A.
Date: 2... | What is required to establish a secondary immune response to a viral infection? | {
"answer_start": [
1972
],
"text": [
"the generation of antigen-specific \"memory\" B and T lymphocytes"
]
} | false |
4,256 | Regulation and Maintenance of an Adoptive T-Cell Dependent Memory B Cell Pool
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120830/
SHA: f4a82ad66962355ffb09e4d1b57fde3e94f0ec53
Authors: Anson, Marie; Amado, Inês; Mailhé, Marie-Pierre; Donnadieu, Emmanuel; Garcia, Sylvie; Huetz, François; Freitas, Antonio A.
Date: 2... | What do immunoglobulin isotype recombination and somatic hyper mutation depend on? | {
"answer_start": [
2230
],
"text": [
"expression of AID"
]
} | false |
4,257 | Regulation and Maintenance of an Adoptive T-Cell Dependent Memory B Cell Pool
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120830/
SHA: f4a82ad66962355ffb09e4d1b57fde3e94f0ec53
Authors: Anson, Marie; Amado, Inês; Mailhé, Marie-Pierre; Donnadieu, Emmanuel; Garcia, Sylvie; Huetz, François; Freitas, Antonio A.
Date: 2... | What was used to quantify the amount of IgM secreting cells? | {
"answer_start": [
11251
],
"text": [
"ELISpot technique"
]
} | false |
4,393 | Optimization Method for Forecasting Confirmed Cases of COVID-19 in China
https://doi.org/10.3390/jcm9030674
SHA: 1d7f8850c5244fdc9b387038e7eeae9bcbbde6d2
Authors: Al-Qaness, Mohammed A. A.; Ewees, Ahmed A.; Fan, Hong; Abd El Aziz, Mohamed
Date: 2020
DOI: 10.3390/jcm9030674
License: cc-by
Abstract: In December 2019,... | Where was the coronavirus discovered? | {
"answer_start": [
377
],
"text": [
"Wuhan, China"
]
} | false |
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