LiteFold/GO · Datasets at Hugging Face

GO:0001819

1,819

positive regulation of cytokine production

biological_process

Any process that activates or increases the frequency, rate or extent of production of a cytokine.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of cytokine production", "positive regulation of cytokine biosynthetic process", "positive regulation of cytokine secretion", "stimulation of cytokine production", "up regulation of cytokine production", "up-regulation of cytokine production", "upregulation of cytokine production" ]

[ "NARROW", "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[ "GO:0042108", "GO:0050715" ]

[]

[ "GO:0001817", "GO:0010628", "GO:0051240" ]

[ "positively_regulates GO:0001816" ]

[ "positively_regulates" ]

[ "GO:0001816" ]

[ "GO:0001816", "GO:0001817", "GO:0010628", "GO:0051240" ]

[ "GO:0065007", "positively_regulates GO:0001816" ]

[]

null

false

true

3

GO:0001820

1,820

serotonin secretion

biological_process

The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.

[ "GOC:ef", "ISBN:0198506732", "ISBN:0781735149" ]

null

[ "5-HT secretion", "5-hydroxytryptamine secretion", "serotonin release" ]

[ "EXACT", "EXACT", "RELATED" ]

[]

[ "GO:0006837", "GO:0023061" ]

[]

[ "GO:0006837", "GO:0023061" ]

[]

null

false

true

2

GO:0001821

1,821

histamine secretion

biological_process

The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.

[ "GOC:mah", "ISBN:0198506732", "ISBN:0781735149" ]

null

[]

[ "GO:0046903", "GO:0051608" ]

[]

[ "GO:0046903", "GO:0051608" ]

[]

null

false

true

8

GO:0001822

1,822

kidney development

biological_process

The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.

[ "GOC:dph", "GOC:mtg_kidney_jan10", "ISBN:0124020607", "ISBN:0721662544" ]

null

[ "nephrogenesis" ]

[ "RELATED" ]

[]

[ "Reactome:R-HSA-9830369 \"Kidney development\"", "Wikipedia:Kidney_development" ]

[ "GO:0048513" ]

[ "part_of GO:0072001" ]

[ "part_of" ]

[ "GO:0072001" ]

[ "GO:0048513", "GO:0072001" ]

[]

null

false

true

4

GO:0001823

1,823

mesonephros development

biological_process

The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will for...

[ "GOC:dph", "ISBN:0124020607", "ISBN:0721662544", "PMID:10535314" ]

null

[ "Wolffian body development" ]

[ "EXACT" ]

[]

[ "GO:0001822" ]

[]

[ "GO:0001822" ]

[]

null

false

true

9

GO:0001824

1,824

blastocyst development

biological_process

The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the develop...

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'.

[ "blastula development" ]

[ "RELATED" ]

[]

[ "GO:0048856" ]

[ "part_of GO:0001701" ]

[ "part_of" ]

[ "GO:0001701" ]

[ "GO:0001701", "GO:0048856" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29162\" xsd:anyURI" ]

null

false

true

2

GO:0001825

1,825

blastocyst formation

biological_process

The initial formation of a blastocyst from a solid ball of cells known as a morula.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'.

[ "blastula formation" ]

[ "RELATED" ]

[]

[ "GO:0048646" ]

[ "part_of GO:0001824" ]

[ "part_of" ]

[ "GO:0001824" ]

[ "GO:0001824", "GO:0048646" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29162\" xsd:anyURI" ]

null

false

true

9

GO:0001826

1,826

inner cell mass cell differentiation

biological_process

The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'.

[]

[ "GO:0030154" ]

[ "part_of GO:0001825" ]

[ "part_of" ]

[ "GO:0001825" ]

[ "GO:0001825", "GO:0030154" ]

[]

null

false

true

3

GO:0001827

1,827

inner cell mass cell fate commitment

biological_process

The cell fate commitment of precursor cells that will become inner cell mass cells.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, compacted morula ; EMAP:13' and 'TS4, inner cell mass ; EMAP:14'.

[]

[ "GO:0045165" ]

[ "part_of GO:0001826" ]

[ "part_of" ]

[ "GO:0001826" ]

[ "GO:0001826", "GO:0045165" ]

[]

null

false

true

1

GO:0001828

1,828

inner cell mass cellular morphogenesis

biological_process

The morphogenesis of cells in the inner cell mass.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.

[]

[ "GO:0000902", "GO:0048598" ]

[ "part_of GO:0001826" ]

[ "part_of" ]

[ "GO:0001826" ]

[ "GO:0000902", "GO:0001826", "GO:0048598" ]

[]

null

false

true

1

GO:0001829

1,829

trophectodermal cell differentiation

biological_process

The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.

[ "trophectoderm cell differentiation" ]

[ "EXACT" ]

[]

[ "GO:0030154" ]

[ "part_of GO:0001825" ]

[ "part_of" ]

[ "GO:0001825" ]

[ "GO:0001825", "GO:0030154" ]

[]

null

false

true

2

GO:0001830

1,830

trophectodermal cell fate commitment

biological_process

The cell fate commitment of precursor cells that will become trophectoderm cells.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.

[ "trophectoderm cell fate commitment" ]

[ "EXACT" ]

[]

[ "GO:0045165" ]

[ "part_of GO:0001829" ]

[ "part_of" ]

[ "GO:0001829" ]

[ "GO:0001829", "GO:0045165" ]

[]

null

false

true

1

GO:0001831

1,831

trophectodermal cellular morphogenesis

biological_process

The morphogenesis of trophectoderm cells.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.

[ "trophectoderm cellular morphogenesis" ]

[ "EXACT" ]

[]

[ "GO:0000902", "GO:0048598" ]

[ "part_of GO:0001829" ]

[ "part_of" ]

[ "GO:0001829" ]

[ "GO:0000902", "GO:0001829", "GO:0048598" ]

[]

null

false

true

3

GO:0001832

1,832

blastocyst growth

biological_process

An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'.

[ "blastula growth" ]

[ "RELATED" ]

[]

[ "GO:0048589" ]

[ "part_of GO:0001824" ]

[ "part_of" ]

[ "GO:0001824" ]

[ "GO:0001824", "GO:0048589" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29162\" xsd:anyURI" ]

null

false

true

2

GO:0001833

1,833

inner cell mass cell proliferation

biological_process

The proliferation of cells in the inner cell mass.

[ "GOC:dph", "GOC:isa_complete", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.

[]

[ "GO:0008283" ]

[ "part_of GO:0001832" ]

[ "part_of" ]

[ "GO:0001832" ]

[ "GO:0001832", "GO:0008283" ]

[]

null

false

true

1

GO:0001834

1,834

trophectodermal cell proliferation

biological_process

The proliferation of cells in the trophectoderm.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.

[ "trophectoderm cell proliferation" ]

[ "EXACT" ]

[]

[ "GO:0008283" ]

[ "part_of GO:0001832" ]

[ "part_of" ]

[ "GO:0001832" ]

[ "GO:0001832", "GO:0008283" ]

[]

null

false

true

9

GO:0001835

1,835

blastocyst hatching

biological_process

The hatching of the cellular blastocyst from the zona pellucida.

[ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ]

See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, zona pellucida ; EMAP:22' and 'TS5, embryo ; EMAP:23'.

[ "blastula hatching" ]

[ "RELATED" ]

[]

[ "GO:0035188" ]

[ "part_of GO:0001824" ]

[ "part_of" ]

[ "GO:0001824" ]

[ "GO:0001824", "GO:0035188" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29162\" xsd:anyURI" ]

null

false

true

3

GO:0001836

1,836

release of cytochrome c from mitochondria

biological_process

The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.

[ "GOC:add", "GOC:mah", "GOC:mtg_apoptosis", "ISBN:0721639976", "PMID:12925707", "PMID:9560217" ]

The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should ...

[]

[ "GO:0008637" ]

[ "part_of GO:0097190" ]

[ "part_of" ]

[ "GO:0097190" ]

[ "GO:0008637", "GO:0097190" ]

[]

null

false

true

6

GO:0001837

1,837

epithelial to mesenchymal transition

biological_process

A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.

[ "GOC:dph", "PMID:14701881" ]

null

[ "EMT", "epithelial-mesenchymal transition", "mesenchymal cell differentiation from epithelial cell" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-9758919 \"Epithelial-Mesenchymal Transition (EMT) during gastrulation\"" ]

[ "GO:0048762" ]

[]

[ "GO:0048762" ]

[]

null

false

true

2

GO:0001838

1,838

embryonic epithelial tube formation

biological_process

The morphogenesis of an embryonic epithelium into a tube-shaped structure.

[ "GOC:dph", "ISBN:0824072820" ]

null

[]

[ "GO:0072175" ]

[ "part_of GO:0016331" ]

[ "part_of" ]

[ "GO:0016331" ]

[ "GO:0016331", "GO:0072175" ]

[]

null

false

true

9

GO:0001839

1,839

neural plate morphogenesis

biological_process

The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.

[ "GOC:dph", "ISBN:0878932437" ]

null

[]

[ "GO:0016331" ]

[ "part_of GO:0001840" ]

[ "part_of" ]

[ "GO:0001840" ]

[ "GO:0001840", "GO:0016331" ]

[]

null

false

true

6

GO:0001840

1,840

neural plate development

biological_process

The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural ...

[ "GOC:dph", "GOC:ef", "ISBN:0878932437", "ISBN:0878932585" ]

null

[]

[ "GO:0060429" ]

[ "part_of GO:0043009" ]

[ "part_of" ]

[ "GO:0043009" ]

[ "GO:0043009", "GO:0060429" ]

[]

null

false

true

8

GO:0001841

1,841

neural tube formation

biological_process

The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.

[ "GOC:dph", "ISBN:0878932437" ]

null

[ "neural tube morphogenesis", "neurulation" ]

[ "EXACT", "EXACT" ]

[ "GO:0001679" ]

[]

[ "Wikipedia:Neurulation" ]

[ "GO:0001838" ]

[ "part_of GO:0021915" ]

[ "part_of" ]

[ "GO:0021915" ]

[ "GO:0001838", "GO:0021915" ]

[]

null

false

true

9

GO:0001842

1,842

neural fold formation

biological_process

The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.

[ "GOC:dph", "ISBN:0878932437" ]

null

[ "neural groove formation" ]

[ "RELATED" ]

[]

[ "GO:0016331", "GO:0048646", "GO:0060571" ]

[ "part_of GO:0014020" ]

[ "part_of" ]

[ "GO:0014020" ]

[ "GO:0014020", "GO:0016331", "GO:0048646", "GO:0060571" ]

[]

null

false

true

5

GO:0001843

1,843

neural tube closure

biological_process

The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.

[ "GOC:dph", "ISBN:0878932437" ]

null

[]

[ "GO:0060606" ]

[ "part_of GO:0014020" ]

[ "part_of" ]

[ "GO:0014020" ]

[ "GO:0014020", "GO:0060606" ]

[]

null

false

true

7

GO:0001844

1,844

obsolete protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

biological_process

OBSOLETE. The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.

[ "GOC:add", "GOC:mtg_apoptosis", "PMID:12952892" ]

The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.

[ "insertion of proteins into mitochondrial membranes during the induction of apoptosis", "protein insertion into mitochondrial membrane during induction of apoptosis", "protein insertion into mitochondrial membrane involved in induction of apoptosis", "protein insertion into mitochondrion membrane during induc...

[ "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0051204" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26245\" xsd:anyURI" ]

null

true

2

GO:0001845

1,845

phagolysosome assembly

biological_process

The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "late phagosome biosynthesis", "late phagosome formation", "phagolysosome formation" ]

[ "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:0007040", "GO:0016050", "GO:0070925" ]

[ "part_of GO:0006909", "part_of GO:0090382" ]

[ "part_of", "part_of" ]

[ "GO:0006909", "GO:0090382" ]

[ "GO:0006909", "GO:0007040", "GO:0016050", "GO:0070925", "GO:0090382" ]

[]

null

false

true

3

GO:0001847

1,847

opsonin receptor activity

molecular_function

Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0004888" ]

[ "has_part GO:0001846" ]

[ "has_part" ]

[ "GO:0001846" ]

[ "GO:0001846", "GO:0004888" ]

[]

null

false

true

7

GO:0001848

1,848

complement binding

molecular_function

Binding to a component or product of the complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways.

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

null

false

true

6

GO:0001850

1,850

complement component C3a binding

molecular_function

Binding to a C3a product of the complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0001848" ]

[]

[ "GO:0001848" ]

[]

null

false

true

2

GO:0001851

1,851

complement component C3b binding

molecular_function

Binding to a C3b product of the complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0001846", "GO:0001848" ]

[]

[ "GO:0001846", "GO:0001848" ]

[]

null

false

true

1

GO:0001852

1,852

complement component iC3b binding

molecular_function

Binding to a iC3b product of the complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0001846", "GO:0001848" ]

[]

[ "GO:0001846", "GO:0001848" ]

[]

null

false

true

9

GO:0001853

1,853

complement component C3dg binding

molecular_function

Binding to a C3dg product of the complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0001848" ]

[]

[ "GO:0001848" ]

[]

null

false

true

8

GO:0001854

1,854

complement component C3d binding

molecular_function

Binding to a C3d product of the complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0001848" ]

[]

[ "GO:0001848" ]

[]

null

false

true

7

GO:0001855

1,855

complement component C4b binding

molecular_function

Binding to a C4b product of the classical complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0001846", "GO:0001848" ]

[]

[ "GO:0001846", "GO:0001848" ]

[]

null

false

true

7

GO:0001856

1,856

complement component C5a binding

molecular_function

Binding to a C5a product of the complement cascade.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0001848" ]

[]

[ "GO:0001848" ]

[]

null

false

true

6

GO:0001857

1,857

complement component C1q receptor activity

molecular_function

Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0001847", "GO:0004875" ]

[ "has_part GO:0001849" ]

[ "has_part" ]

[ "GO:0001849" ]

[ "GO:0001847", "GO:0001849", "GO:0004875" ]

[]

null

false

true

7

GO:0001858

1,858

complement component iC3b receptor activity

molecular_function

Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0001847", "GO:0004875" ]

[ "has_part GO:0001852" ]

[ "has_part" ]

[ "GO:0001852" ]

[ "GO:0001847", "GO:0001852", "GO:0004875" ]

[]

null

false

true

7

GO:0001859

1,859

complement component C3dg receptor activity

molecular_function

Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0004875" ]

[ "has_part GO:0001853" ]

[ "has_part" ]

[ "GO:0001853" ]

[ "GO:0001853", "GO:0004875" ]

[]

null

false

true

1

GO:0001860

1,860

complement component C3d receptor activity

molecular_function

Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0004875" ]

[ "has_part GO:0001854" ]

[ "has_part" ]

[ "GO:0001854" ]

[ "GO:0001854", "GO:0004875" ]

[]

null

false

true

8

GO:0001861

1,861

complement component C4b receptor activity

molecular_function

Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0001847", "GO:0004875" ]

[ "has_part GO:0001855" ]

[ "has_part" ]

[ "GO:0001855" ]

[ "GO:0001847", "GO:0001855", "GO:0004875" ]

[]

null

false

true

7

GO:0001862

1,862

collectin binding

molecular_function

Binding to a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.

[ "GOC:add", "ISBN:0781735149" ]

Note that collectins include such proteins as mannose-binding lectins (MBL) and surfactant proteins A and D (SP-A and SP-D).

[]

[ "GO:0001846" ]

[]

[ "GO:0001846" ]

[]

null

false

true

4

GO:0001864

1,864

pentraxin binding

molecular_function

Binding to a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.

[ "GOC:add", "ISBN:0781735149" ]

Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP).

[]

[ "GO:0001846" ]

[]

[ "GO:0001846" ]

[]

null

false

true

6

GO:0001865

1,865

NK T cell differentiation

biological_process

The process in which a precursor cell type acquires the specialized features of a NK T cell.

[ "GOC:add", "ISBN:0781735149", "PMID:10704459" ]

Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergo...

[ "natural killer T cell differentiation", "natural T cell differentiation", "NK T cell development", "NK T lymphocyte differentiation", "NK T-cell differentiation", "NK T-lymphocyte differentiation", "NKT cell differentiation", "NT cell differentiation" ]

[ "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0046632" ]

[]

[ "GO:0046632" ]

[]

null

false

true

9

GO:0001866

1,866

NK T cell proliferation

biological_process

The expansion of a NK T cell population by cell division.

[ "GOC:add", "ISBN:0781735149", "PMID:10704459" ]

Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments.

[ "natural killer T cell proliferation", "natural T cell proliferation", "NK T lymphocyte proliferation", "NK T-cell proliferation", "NK T-lymphocyte proliferation", "NKT cell proliferation", "NT cell proliferation" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0046633", "GO:0051132" ]

[]

[ "GO:0046633", "GO:0051132" ]

[]

null

false

true

1

GO:0001868

1,868

regulation of complement activation, lectin pathway

biological_process

Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "regulation of complement cascade, lectin pathway" ]

[ "EXACT" ]

[]

[ "GO:0030449", "GO:0045088" ]

[ "regulates GO:0001867" ]

[ "regulates" ]

[ "GO:0001867" ]

[ "GO:0001867", "GO:0030449", "GO:0045088" ]

[ "GO:0065007", "regulates GO:0001867" ]

[]

null

false

true

2

GO:0001869

1,869

negative regulation of complement activation, lectin pathway

biological_process

Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "down regulation of complement activation, lectin pathway", "down-regulation of complement activation, lectin pathway", "downregulation of complement activation, lectin pathway", "inhibition of complement activation, lectin pathway", "negative regulation of complement cascade, lectin pathway" ]

[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT" ]

[]

[ "GO:0001868", "GO:0045824", "GO:0045916" ]

[ "negatively_regulates GO:0001867" ]

[ "negatively_regulates" ]

[ "GO:0001867" ]

[ "GO:0001867", "GO:0001868", "GO:0045824", "GO:0045916" ]

[ "GO:0065007", "negatively_regulates GO:0001867" ]

[]

null

false

true

1

GO:0001870

1,870

positive regulation of complement activation, lectin pathway

biological_process

Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of complement activation, lectin pathway", "positive regulation of complement cascade, lectin pathway", "stimulation of complement activation, lectin pathway", "up regulation of complement activation, lectin pathway", "up-regulation of complement activation, lectin pathway", "upregulation of c...

[ "NARROW", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001868", "GO:0045089", "GO:0045917" ]

[ "positively_regulates GO:0001867" ]

[ "positively_regulates" ]

[ "GO:0001867" ]

[ "GO:0001867", "GO:0001868", "GO:0045089", "GO:0045917" ]

[ "GO:0065007", "positively_regulates GO:0001867" ]

[]

null

false

true

8

GO:0001871

1,871

obsolete pattern binding

molecular_function

OBSOLETE. Binding to a repeating or polymeric structure, such as a polysaccharide or peptidoglycan.

[ "PMID:12072369", "PMID:12225919", "PMID:12507420", "PMID:12925128", "PMID:14523544" ]

This term was obsoleted because it was an unnecessary grouping term.

[ "pattern recognition activity" ]

[ "BROAD" ]

[]

null

true

2

GO:0001872

1,872

(1->3)-beta-D-glucan binding

molecular_function

Binding to a (1->3)-beta-D-glucan.

[ "PMID:14707091" ]

null

[ "1,3-beta-D-glucan binding", "callose binding", "zymosan binding" ]

[ "EXACT", "NARROW", "NARROW" ]

[ "GO:0080087" ]

[]

[ "GO:0030247" ]

[]

[ "GO:0030247" ]

[]

null

false

true

5

GO:0001874

1,874

(1->3)-beta-D-glucan immune receptor activity

molecular_function

Combining with (1->3)-beta-D-glucans to initiate an innate immune response.

[ "PMID:14707091" ]

null

[ "(1,3)-beta-D-glucan receptor activity", "(1->3)-beta-D-glucan receptor activity", "1,3-beta-D-glucan receptor activity", "beta-1,3-D-glucan receptor activity", "zymosan receptor activity" ]

[ "EXACT", "BROAD", "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0001873" ]

[ "has_part GO:0001872" ]

[ "has_part" ]

[ "GO:0001872" ]

[ "GO:0001872", "GO:0001873" ]

[]

null

false

true

7

GO:0001875

1,875

lipopolysaccharide immune receptor activity

molecular_function

Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.

[ "PMID:14609719", "PMID:15379975" ]

null

[ "endotoxin receptor activity", "lipopolysaccharide receptor activity", "LPS receptor activity" ]

[ "BROAD", "BROAD", "EXACT" ]

[]

[ "GO:0038187" ]

[ "has_part GO:0001530", "part_of GO:0031663" ]

[ "has_part", "part_of" ]

[ "GO:0001530", "GO:0031663" ]

[ "GO:0001530", "GO:0031663", "GO:0038187" ]

[]

null

false

true

7

GO:0001876

1,876

lipoarabinomannan binding

molecular_function

Binding to lipoarabinomannan.

[ "PMID:10586073" ]

null

[ "LAM binding" ]

[ "EXACT" ]

[]

[ "GO:0034235" ]

[]

[ "GO:0034235" ]

[]

null

false

true

4

GO:0001877

1,877

lipoarabinomannan immune receptor activity

molecular_function

Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response.

[ "PMID:10586073" ]

null

[ "LAM receptor activity", "lipoarabinomannan receptor activity" ]

[ "EXACT", "BROAD" ]

[]

[ "GO:0038187" ]

[ "has_part GO:0001876" ]

[ "has_part" ]

[ "GO:0001876" ]

[ "GO:0001876", "GO:0038187" ]

[]

null

false

true

6

GO:0001878

1,878

response to yeast

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.

[ "PMID:14707091" ]

defined as response to Saccharomycotina (true yeasts). This excludes fission yeast.

[]

[ "GO:0009620" ]

[]

[ "GO:0009620" ]

[]

null

false

true

6

GO:0001879

1,879

detection of yeast

biological_process

The series of events in which a stimulus from a yeast is received and converted into a molecular signal.

[ "PMID:14707091" ]

null

[]

[ "GO:0001878", "GO:0016046" ]

[]

[ "GO:0001878", "GO:0016046" ]

[]

null

false

true

9

GO:0001881

1,881

receptor recycling

biological_process

The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.

[ "GOC:dph" ]

null

[]

[ "GO:0043112" ]

[ "has_part GO:0006897" ]

[ "has_part" ]

[ "GO:0006897" ]

[ "GO:0006897", "GO:0043112" ]

[]

null

false

true

1

GO:0001882

1,882

nucleoside binding

molecular_function

Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.

[ "GOC:hjd" ]

null

[]

[ "goslim_pir" ]

[]

[ "GO:0097367", "GO:1901363" ]

[]

[ "GO:0097367", "GO:1901363" ]

[]

null

false

true

6

GO:0001883

1,883

purine nucleoside binding

molecular_function

Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.

[ "GOC:hjd" ]

null

[]

[ "GO:0001882" ]

[]

[ "GO:0001882" ]

[]

null

false

true

1

GO:0001885

1,885

endothelial cell development

biological_process

The progression of an endothelial cell over time, from its formation to the mature structure.

[ "GOC:dph" ]

null

[]

[ "GO:0002064" ]

[ "part_of GO:0045446" ]

[ "part_of" ]

[ "GO:0045446" ]

[ "GO:0002064", "GO:0045446" ]

[]

null

false

true

8

GO:0001886

1,886

endothelial cell morphogenesis

biological_process

The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.

[ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ]

null

[]

[ "GO:0003382" ]

[ "part_of GO:0001885" ]

[ "part_of" ]

[ "GO:0001885" ]

[ "GO:0001885", "GO:0003382" ]

[]

null

false

true

2

GO:0001887

1,887

selenium compound metabolic process

biological_process

The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.

[ "PMID:12730456" ]

null

[ "selenium compound metabolism", "selenium metabolic process", "selenium metabolism" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-2408499 \"Formation of selenosugars for excretion\"", "Reactome:R-HSA-2408508 \"Metabolism of ingested SeMet, Sec, MeSec into H2Se\"", "Reactome:R-HSA-2408550 \"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se\"", "Reactome:R-HSA-2408552 \"Methylation of MeSeH for excretion\"", "Reactome:R...

[ "GO:0008152" ]

[]

[ "GO:0008152" ]

[]

null

false

true

9

GO:0001888

1,888

glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

molecular_function

Catalysis of the reaction: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H+ + UDP.

[ "EC:2.4.1.223", "RHEA:16221" ]

null

[ "alpha-1,4-N-acetylglucosaminyltransferase activity", "alpha-N-acetylglucosaminyltransferase I activity", "alpha1,4-N-acetylglucosaminyltransferase activity", "glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-...

[ "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "EC:2.4.1.223", "MetaCyc:2.4.1.223-RXN", "Reactome:R-HSA-9953259 \"EXTL3 dimer transfers GlcNAc to the GAG linker\"", "RHEA:16221" ]

[ "GO:0008375" ]

[]

[ "GO:0008375" ]

[]

[ "skos:exactMatch EC:2.4.1.223", "skos:exactMatch RHEA:16221", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28762\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

5

GO:0001889

1,889

liver development

biological_process

The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin ...

[ "GOC:add", "ISBN:068340007X" ]

null

[]

[ "GO:0048732" ]

[ "part_of GO:0061008" ]

[ "part_of" ]

[ "GO:0061008" ]

[ "GO:0048732", "GO:0061008" ]

[]

null

false

true

8

GO:0001890

1,890

placenta development

biological_process

The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.

[ "GOC:add", "ISBN:068340007X" ]

null

[ "placental development", "placentation" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0048513" ]

[]

[ "GO:0048513" ]

[]

null

false

true

1

GO:0001891

1,891

phagocytic cup

cellular_component

An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.

[ "PMID:10358769" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0005886" ]

[ "part_of" ]

[ "GO:0005886" ]

[ "GO:0005886", "GO:0110165" ]

[]

null

false

true

7

GO:0001892

1,892

embryonic placenta development

biological_process

The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.

[ "GOC:add", "ISBN:068340007X" ]

null

[ "fetal placenta development" ]

[ "EXACT" ]

[]

[ "GO:0048568" ]

[ "part_of GO:0001701", "part_of GO:0001890" ]

[ "part_of", "part_of" ]

[ "GO:0001701", "GO:0001890" ]

[ "GO:0001701", "GO:0001890", "GO:0048568" ]

[]

null

false

true

4

GO:0001893

1,893

maternal placenta development

biological_process

Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.

[ "GOC:add", "ISBN:068340007X" ]

null

[ "decidua development" ]

[ "RELATED" ]

[]

[ "GO:0003006", "GO:0048856", "GO:0060135" ]

[ "part_of GO:0001890" ]

[ "part_of" ]

[ "GO:0001890" ]

[ "GO:0001890", "GO:0003006", "GO:0048856", "GO:0060135" ]

[]

null

false

true

7

GO:0001894

1,894

tissue homeostasis

biological_process

A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.

[ "GOC:add", "GOC:isa_complete" ]

null

[ "tissue maintenance" ]

[ "NARROW" ]

[]

[ "GO:0060249" ]

[ "part_of GO:0048871" ]

[ "part_of" ]

[ "GO:0048871" ]

[ "GO:0048871", "GO:0060249" ]

[]

null

false

true

6

GO:0001895

1,895

retina homeostasis

biological_process

A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.

[ "GOC:add", "GOC:dph", "GOC:tb", "PMID:15365173", "PMID:15365178" ]

null

[]

[ "GO:0001894" ]

[]

[ "GO:0001894" ]

[]

null

false

true

7

GO:0001896

1,896

autolysis

biological_process

A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.

[ "GOC:add", "GOC:jh2", "GOC:mtg_apoptosis", "PMID:10974124", "PMID:19286987", "PMID:26811896" ]

null

[]

[ "Wikipedia:Autolysis" ]

[ "GO:0012501" ]

[]

[ "GO:0012501" ]

[]

null

false

true

1

GO:0001897

1,897

symbiont-mediated cytolysis of host cell

biological_process

A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:11423190", "PMID:23748204", "PMID:24204713", "PMID:27405240" ]

null

[ "cytolysis by organism of host cells", "cytolysis by symbiont of host cells", "pathogenesis" ]

[ "EXACT", "EXACT", "RELATED" ]

[]

[ "GO:0001907", "GO:0051715" ]

[]

[ "GO:0001907", "GO:0051715" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26938\" xsd:anyURI" ]

null

false

true

8

GO:0001898

1,898

obsolete regulation of cytolysis by symbiont of host cells

biological_process

OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "GOC:add", "GOC:dph", "GOC:tb" ]

This term was obsoleted because it has been used inconsistently.

[ "regulation by symbiont of cytolysis of host cells" ]

[ "EXACT" ]

[]

[ "GO:0031640" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13041\" xsd:anyURI" ]

null

true

6

GO:0001900

1,900

obsolete positive regulation of cytolysis by symbiont of host cells

biological_process

OBSOLETE. Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "GOC:add", "GOC:dph", "GOC:tb" ]

This term was obsoleted because it has been used inconsistently.

[ "activation by symbiont of cytolysis of host cells", "positive regulation by symbiont of cytolysis of host cells", "stimulation by symbiont of cytolysis of host cells", "up regulation by symbiont of cytolysis of host cells", "up-regulation by symbiont of cytolysis of host cells", "upregulation by symbiont...

[ "NARROW", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001907" ]

[]

null

true

9

GO:0001905

1,905

activation of membrane attack complex

biological_process

The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of MAC", "activation of TCC", "activation of terminal complement complex", "activation of the terminal complement cascade", "MAC assembly", "MAC formation", "membrane attack complex assembly", "membrane attack complex formation" ]

[ "EXACT", "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006956" ]

[]

[ "GO:0006956" ]

[]

null

false

true

4

GO:0001906

1,906

cell killing

biological_process

Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.

[ "GOC:add" ]

null

[ "necrosis" ]

[ "RELATED" ]

[]

[ "goslim_pir" ]

[]

[ "GO:0009987" ]

[]

[ "GO:0009987" ]

[]

[ "GO:0044848" ]

[]

null

false

true

9

GO:0001907

1,907

symbiont-mediated killing of host cell

biological_process

A process mediated by a symbiont that results in the death of a cell in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "GOC:add", "PMID:11123917", "PMID:22992735", "PMID:23230295", "PMID:26633512" ]

null

[ "killing by symbiont of host cells", "pathogenesis" ]

[ "EXACT", "RELATED" ]

[]

[ "goslim_virus" ]

[ "Reactome:R-HSA-9637698 \"Phagocyte cell death caused by cytosolic Mtb\"" ]

[ "GO:0031640", "GO:0051701" ]

[]

[ "GO:0031640", "GO:0051701" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27342\" xsd:anyURI" ]

null

false

true

8

GO:0001909

1,909

leukocyte mediated cytotoxicity

biological_process

The directed killing of a target cell by a leukocyte.

[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149", "PMID:11911826" ]

Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system.

[ "immune cell mediated cell death", "immune cell mediated cell killing", "immune cell mediated cytotoxicity", "leucocyte mediated cytotoxicity" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001906", "GO:0002443" ]

[]

[ "GO:0001906", "GO:0002443" ]

[]

null

false

true

7

GO:0001910

1,910

regulation of leukocyte mediated cytotoxicity

biological_process

Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity.

[ "GOC:add", "ISBN:0781735149", "PMID:11911826" ]

null

[ "regulation of immune cell mediated cell death", "regulation of immune cell mediated cell killing", "regulation of immune cell mediated cytotoxicity", "regulation of leucocyte mediated cytotoxicity" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0002703", "GO:0031341" ]

[ "regulates GO:0001909" ]

[ "regulates" ]

[ "GO:0001909" ]

[ "GO:0001909", "GO:0002703", "GO:0031341" ]

[ "GO:0065007", "regulates GO:0001909" ]

[]

null

false

true

1

GO:0001911

1,911

negative regulation of leukocyte mediated cytotoxicity

biological_process

Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity.

[ "GOC:add", "ISBN:0781735149", "PMID:11911826" ]

null

[ "down regulation of leukocyte mediated cytotoxicity", "down-regulation of leukocyte mediated cytotoxicity", "downregulation of leukocyte mediated cytotoxicity", "inhibition of leukocyte mediated cytotoxicity", "negative regulation of immune cell mediated cytotoxicity", "negative regulation of leucocyte me...

[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT" ]

[]

[ "GO:0001910", "GO:0002704", "GO:0031342" ]

[ "negatively_regulates GO:0001909" ]

[ "negatively_regulates" ]

[ "GO:0001909" ]

[ "GO:0001909", "GO:0001910", "GO:0002704", "GO:0031342" ]

[ "GO:0065007", "negatively_regulates GO:0001909" ]

[]

null

false

true

3

GO:0001912

1,912

positive regulation of leukocyte mediated cytotoxicity

biological_process

Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity.

[ "GOC:add", "ISBN:0781735149", "PMID:11911826" ]

null

[ "activation of leukocyte mediated cytotoxicity", "positive regulation of immune cell mediated cytotoxicity", "positive regulation of leucocyte mediated cytotoxicity", "stimulation of leukocyte mediated cytotoxicity", "up regulation of leukocyte mediated cytotoxicity", "up-regulation of leukocyte mediated ...

[ "NARROW", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001910", "GO:0002705", "GO:0031343" ]

[ "positively_regulates GO:0001909" ]

[ "positively_regulates" ]

[ "GO:0001909" ]

[ "GO:0001909", "GO:0001910", "GO:0002705", "GO:0031343" ]

[ "GO:0065007", "positively_regulates GO:0001909" ]

[]

null

false

true

4

GO:0001913

1,913

T cell mediated cytotoxicity

biological_process

The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

[ "GOC:add", "GOC:pr", "ISBN:0781735149", "PMID:11911826" ]

Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, in...

[ "T cell mediated apoptosis", "T cell mediated cell death", "T cell mediated cell killing", "T cell mediated cytolysis", "T lymphocyte mediated cytotoxicity", "T-cell mediated apoptosis", "T-cell mediated cell death", "T-cell mediated cell killing", "T-cell mediated cytotoxicity", "T-lymphocyte med...

[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001909", "GO:0002456" ]

[]

[ "GO:0001909", "GO:0002456" ]

[]

null

false

true

6

GO:0001914

1,914

regulation of T cell mediated cytotoxicity

biological_process

Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "regulation of T cell mediated apoptosis", "regulation of T cell mediated cell death", "regulation of T cell mediated cell killing", "regulation of T cell mediated cytolysis", "regulation of T lymphocyte mediated cytotoxicity", "regulation of T-cell mediated apoptosis", "regulation of T-cell mediated ce...

[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT" ]

[]

[ "GO:0001910", "GO:0002709" ]

[ "regulates GO:0001913" ]

[ "regulates" ]

[ "GO:0001913" ]

[ "GO:0001910", "GO:0001913", "GO:0002709" ]

[ "GO:0065007", "regulates GO:0001913" ]

[]

null

false

true

3

GO:0001915

1,915

negative regulation of T cell mediated cytotoxicity

biological_process

Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "down regulation of T cell mediated cytotoxicity", "down-regulation of T cell mediated cytotoxicity", "downregulation of T cell mediated cytotoxicity", "inhibition of T cell mediated cytotoxicity", "negative regulation of T cell mediated apoptosis", "negative regulation of T cell mediated cell death", "...

[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT" ]

[]

[ "GO:0001911", "GO:0001914", "GO:0002710" ]

[ "negatively_regulates GO:0001913" ]

[ "negatively_regulates" ]

[ "GO:0001913" ]

[ "GO:0001911", "GO:0001913", "GO:0001914", "GO:0002710" ]

[ "GO:0065007", "negatively_regulates GO:0001913" ]

[]

null

false

true

1

GO:0001916

1,916

positive regulation of T cell mediated cytotoxicity

biological_process

Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of T cell mediated cytotoxicity", "positive regulation of T cell mediated apoptosis", "positive regulation of T cell mediated cell death", "positive regulation of T cell mediated cell killing", "positive regulation of T cell mediated cytolysis", "positive regulation of T lymphocyte mediated cy...

[ "NARROW", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001912", "GO:0001914", "GO:0002711" ]

[ "positively_regulates GO:0001913" ]

[ "positively_regulates" ]

[ "GO:0001913" ]

[ "GO:0001912", "GO:0001913", "GO:0001914", "GO:0002711" ]

[ "GO:0065007", "positively_regulates GO:0001913" ]

[]

null

false

true

5

GO:0001917

1,917

photoreceptor inner segment

cellular_component

The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.

[ "GOC:add", "PMID:12019563" ]

null

[]

[ "goslim_pir" ]

[]

[ "GO:0110165" ]

[]

[ "GO:0110165" ]

[]

null

false

true

7

GO:0001918

1,918

farnesylated protein binding

molecular_function

Binding to a farnesylated protein.

[ "GOC:add", "PMID:14555765" ]

null

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

null

false

true

6

GO:0001919

1,919

regulation of receptor recycling

biological_process

Any process that modulates the frequency, rate, or extent of receptor recycling.

[ "GOC:add" ]

null

[]

[ "GO:0023051", "GO:0060255" ]

[ "regulates GO:0001881" ]

[ "regulates" ]

[ "GO:0001881" ]

[ "GO:0001881", "GO:0023051", "GO:0060255" ]

[ "GO:0065007", "regulates GO:0001881" ]

[]

null

false

true

3

GO:0001920

1,920

negative regulation of receptor recycling

biological_process

Any process that stops, prevents, or reduces the rate of receptor recycling.

[ "GOC:add" ]

null

[ "down regulation of receptor recycling", "down-regulation of receptor recycling", "downregulation of receptor recycling", "inhibition of receptor recycling" ]

[ "EXACT", "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0001919", "GO:0010605", "GO:0023057" ]

[ "negatively_regulates GO:0001881" ]

[ "negatively_regulates" ]

[ "GO:0001881" ]

[ "GO:0001881", "GO:0001919", "GO:0010605", "GO:0023057" ]

[ "GO:0065007", "negatively_regulates GO:0001881" ]

[]

null

false

true

9

GO:0001921

1,921

positive regulation of receptor recycling

biological_process

Any process that activates or increases the frequency, rate or extent of receptor recycling.

[ "GOC:add" ]

null

[ "activation of receptor recycling", "stimulation of receptor recycling", "up regulation of receptor recycling", "up-regulation of receptor recycling", "upregulation of receptor recycling" ]

[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001919", "GO:0010604", "GO:0023056" ]

[ "positively_regulates GO:0001881" ]

[ "positively_regulates" ]

[ "GO:0001881" ]

[ "GO:0001881", "GO:0001919", "GO:0010604", "GO:0023056" ]

[ "GO:0065007", "positively_regulates GO:0001881" ]

[]

null

false

true

5

GO:0001922

1,922

B-1 B cell homeostasis

biological_process

The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found pred...

[ "GOC:add", "ISBN:0781735149" ]

Note that this term represents the return of B-1 B cell levels to stable numbers following an immune response, as well as the proliferation and elimination of B-1 B cells in a organism required to maintain stable numbers in the absence of an outside stimulus.

[ "B-1 B lymphocyte homeostasis", "B-1 B-cell homeostasis", "B-1 B-lymphocyte homeostasis" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001782" ]

[]

[ "GO:0001782" ]

[]

null

false

true

1

GO:0001924

1,924

regulation of B-1 B cell differentiation

biological_process

Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.

[ "GOC:add", "ISBN:0781735149" ]

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

[ "regulation of B-1 B cell development", "regulation of B-1 B lymphocyte differentiation", "regulation of B-1 B-cell differentiation", "regulation of B-1 B-lymphocyte differentiation" ]

[ "RELATED", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0045577" ]

[ "regulates GO:0001923" ]

[ "regulates" ]

[ "GO:0001923" ]

[ "GO:0001923", "GO:0045577" ]

[ "GO:0065007", "regulates GO:0001923" ]

[]

null

false

true

8

GO:0001925

1,925

negative regulation of B-1 B cell differentiation

biological_process

Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.

[ "GOC:add", "ISBN:0781735149" ]

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

[ "down regulation of B-1 B cell differentiation", "down-regulation of B-1 B cell differentiation", "downregulation of B-1 B cell differentiation", "inhibition of B-1 B cell differentiation", "negative regulation of B-1 B cell development", "negative regulation of B-1 B lymphocyte differentiation", "negat...

[ "EXACT", "EXACT", "EXACT", "NARROW", "RELATED", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001924", "GO:0045578" ]

[ "negatively_regulates GO:0001923" ]

[ "negatively_regulates" ]

[ "GO:0001923" ]

[ "GO:0001923", "GO:0001924", "GO:0045578" ]

[ "GO:0065007", "negatively_regulates GO:0001923" ]

[]

null

false

true

3

GO:0001926

1,926

positive regulation of B-1 B cell differentiation

biological_process

Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.

[ "GOC:add", "ISBN:0781735149" ]

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

[ "activation of B-1 B cell differentiation", "positive regulation of B-1 B cell development", "positive regulation of B-1 B lymphocyte differentiation", "positive regulation of B-1 B-cell differentiation", "positive regulation of B-1 B-lymphocyte differentiation", "stimulation of B-1 B cell differentiation...

[ "NARROW", "RELATED", "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001924", "GO:0045579" ]

[ "positively_regulates GO:0001923" ]

[ "positively_regulates" ]

[ "GO:0001923" ]

[ "GO:0001923", "GO:0001924", "GO:0045579" ]

[ "GO:0065007", "positively_regulates GO:0001923" ]

[]

null

false

true

5

GO:0001927

1,927

exocyst assembly

biological_process

The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.

[ "GOC:hjd", "PMID:9700152", "Wikipedia:Exocyst" ]

null

[]

[ "GO:0065003", "GO:0140029" ]

[ "part_of GO:0006904" ]

[ "part_of" ]

[ "GO:0006904" ]

[ "GO:0006904", "GO:0065003", "GO:0140029" ]

[]

null

false

true

5

GO:0001928

1,928

regulation of exocyst assembly

biological_process

Any process that modulates the frequency, rate or extent of exocyst assembly.

[ "GOC:hjd" ]

Note that the assembly is regulated by several small GTPases of the Rab and Rho families.

[]

[ "GO:0043254", "GO:0106020" ]

[ "regulates GO:0001927" ]

[ "regulates" ]

[ "GO:0001927" ]

[ "GO:0001927", "GO:0043254", "GO:0106020" ]

[ "GO:0065007", "regulates GO:0001927" ]

[]

null

false

true

6

GO:0001930

1,930

positive regulation of exocyst assembly

biological_process

Any process that increases the rate or extent of exocyst assembly.

[ "GOC:hjd" ]

null

[ "activation of exocyst assembly", "stimulation of exocyst assembly", "up regulation of exocyst assembly", "up-regulation of exocyst assembly", "upregulation of exocyst assembly" ]

[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001928", "GO:0031334" ]

[ "positively_regulates GO:0001927" ]

[ "positively_regulates" ]

[ "GO:0001927" ]

[ "GO:0001927", "GO:0001928", "GO:0031334" ]

[ "GO:0065007", "positively_regulates GO:0001927" ]

[]

null

false

true

6

GO:0001931

1,931

uropod

cellular_component

A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.

[ "GOC:add", "ISBN:0781735149", "PMID:12714569", "PMID:12787750" ]

null

[ "distal pole complex", "retractile pole", "uropodium" ]

[ "RELATED", "RELATED", "EXACT" ]

[]

[ "GO:0120025" ]

[ "part_of GO:0031254" ]

[ "part_of" ]

[ "GO:0031254" ]

[ "GO:0031254", "GO:0120025" ]

[ "GO:0120025", "part_of GO:0031254" ]

[]

null

false

true

2

GO:0001932

1,932

regulation of protein phosphorylation

biological_process

Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.

[ "GOC:hjd" ]

null

[ "regulation of protein amino acid phosphorylation" ]

[ "EXACT" ]

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0031399", "GO:0042325" ]

[ "regulates GO:0006468" ]

[ "regulates" ]

[ "GO:0006468" ]

[ "GO:0006468", "GO:0031399", "GO:0042325" ]

[ "GO:0065007", "regulates GO:0006468" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28278\" xsd:anyURI" ]

null

false

true

6

GO:0001933

1,933

negative regulation of protein phosphorylation

biological_process

Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.

[ "GOC:hjd" ]

null

[ "down regulation of protein amino acid phosphorylation", "down-regulation of protein amino acid phosphorylation", "downregulation of protein amino acid phosphorylation", "inhibition of protein amino acid phosphorylation", "negative regulation of protein amino acid phosphorylation" ]

[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT" ]

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0001932", "GO:0031400", "GO:0042326" ]

[ "negatively_regulates GO:0006468" ]

[ "negatively_regulates" ]

[ "GO:0006468" ]

[ "GO:0001932", "GO:0006468", "GO:0031400", "GO:0042326" ]

[ "GO:0065007", "negatively_regulates GO:0006468" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28278\" xsd:anyURI" ]

null

false

true

9