go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0001565
1,565
phorbol ester receptor activity
molecular_function
Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity.
[ "GOC:ai", "GOC:signaling", "PMID:10506570" ]
null
[]
[]
[]
[]
[]
[ "GO:0038023" ]
[]
[]
[]
[ "GO:0038023" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001566
1,566
non-kinase phorbol ester receptor activity
molecular_function
Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity.
[ "PMID:10506570" ]
null
[]
[]
[]
[]
[]
[ "GO:0001565" ]
[]
[]
[]
[ "GO:0001565" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001567
1,567
cholesterol 25-hydroxylase activity
molecular_function
Catalysis of the reaction: AH2 + cholesterol + O2 = 25-hydroxycholesterol + A + H2O.
[ "RHEA:21104" ]
null
[ "cholesterol 25-monooxygenase activity", "cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity" ]
[ "RELATED", "RELATED" ]
[]
[]
[ "EC:1.14.99.38", "KEGG_REACTION:R07218", "MetaCyc:1.14.99.38-RXN", "RHEA:21104", "RHEA:46132" ]
[ "GO:0008395", "GO:0016705" ]
[]
[]
[]
[ "GO:0008395", "GO:0016705" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.14.99.38", "skos:exactMatch RHEA:21104", "skos:narrowMatch RHEA:46132" ]
null
null
false
true
7
GO:0001568
1,568
blood vessel development
biological_process
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
[ "GOC:hjd", "UBERON:0001981" ]
null
[]
[]
[]
[]
[]
[ "GO:0048856" ]
[ "part_of GO:0001944" ]
[ "part_of" ]
[ "GO:0001944" ]
[ "GO:0001944", "GO:0048856" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001569
1,569
branching involved in blood vessel morphogenesis
biological_process
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
[ "GOC:dph" ]
null
[ "patterning of blood vessels" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0048754" ]
[ "part_of GO:0001525" ]
[ "part_of" ]
[ "GO:0001525" ]
[ "GO:0001525", "GO:0048754" ]
[ "GO:0048754", "part_of GO:0048514" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001570
1,570
vasculogenesis
biological_process
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
[ "PMID:8999798" ]
null
[ "vascular morphogenesis" ]
[ "EXACT" ]
[]
[]
[ "Wikipedia:Vasculogenesis" ]
[ "GO:0030154" ]
[ "part_of GO:0048514" ]
[ "part_of" ]
[ "GO:0048514" ]
[ "GO:0030154", "GO:0048514" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001571
1,571
non-tyrosine kinase fibroblast growth factor receptor activity
molecular_function
Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity.
[ "GOC:signaling", "PMID:11418238" ]
null
[ "non-tyrosine kinase FGF receptor activity", "non-tyrosine kinase FGFR activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004888" ]
[]
[]
[]
[ "GO:0004888" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001572
1,572
lactosylceramide biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of lactosylceramides that begins with the synthesis of a disaccharide core 4-Gal-beta-1,4-Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units and is also the precursor for the synthesis of gangliosides...
[ "PMID:35536927" ]
null
[ "lacto-series glycosphingolipid biosynthesis", "lactosylceramide anabolism", "lactosylceramide biosynthesis", "lactosylceramide formation", "lactosylceramide synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-7839" ]
[ "GO:0006688", "GO:0046513" ]
[]
[]
[]
[ "GO:0006688", "GO:0046513" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30616\" xsd:anyURI" ]
null
null
false
true
1
GO:0001573
1,573
ganglioside metabolic process
biological_process
The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
[ "ISBN:0198506732" ]
null
[ "ganglioside metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006672", "GO:0006687" ]
[]
[]
[]
[ "GO:0006672", "GO:0006687" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001575
1,575
globoside metabolic process
biological_process
The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.
[ "ISBN:0198506732" ]
null
[ "globoside metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006687" ]
[]
[]
[]
[ "GO:0006687" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001576
1,576
globoside biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of gobliosides that begins with the synthesis of a tetrasaccharide core GalNAc-beta-1,3-Gal-alpha-1,4-Gal-beta-1,4-Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units.
[ "PMID:35536927" ]
null
[ "globo-series glycosphingolipid biosynthesis", "globoside anabolism", "globoside biosynthesis", "globoside formation", "globoside synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-7838" ]
[ "GO:0001575", "GO:0006688" ]
[]
[]
[]
[ "GO:0001575", "GO:0006688" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29130\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30616\" xsd:anyURI" ]
null
null
false
true
7
GO:0001577
1,577
obsolete galectin
molecular_function
OBSOLETE. A lectin that exhibits calcium independent binding of beta-galactoside sugars.
[ "PMID:9786891" ]
This term was made obsolete because it refers to a class of gene products.
[ "galectin", "S-type lectin" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0007157", "GO:0016936" ]
[]
null
null
true
true
3
GO:0001578
1,578
microtubule bundle formation
biological_process
A process that results in a parallel arrangement of microtubules.
[ "GOC:dph" ]
null
[ "microtubule bundling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000226" ]
[]
[]
[]
[ "GO:0000226" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001579
1,579
medium-chain fatty acid transport
biological_process
The directed movement of a medium-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
[ "GOC:ai" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[]
[]
[]
[]
[]
[ "GO:0015908" ]
[]
[]
[]
[ "GO:0015908" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26445\" xsd:anyURI" ]
null
null
false
true
9
GO:0001580
1,580
detection of chemical stimulus involved in sensory perception of bitter taste
biological_process
The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.
[ "GOC:curators" ]
null
[ "bitter taste detection", "perception of bitter taste, detection of chemical stimulus", "perception of bitter taste, sensory transduction of chemical stimulus", "sensory detection of bitter taste", "sensory detection of chemical stimulus during perception of bitter taste", "sensory transduction of bitter ...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0050912" ]
[ "part_of GO:0050913" ]
[ "part_of" ]
[ "GO:0050913" ]
[ "GO:0050912", "GO:0050913" ]
[ "GO:0009593", "part_of GO:0050913" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001581
1,581
detection of chemical stimulus involved in sensory perception of sour taste
biological_process
The series of events required for a sour taste stimulus to be received and converted to a molecular signal.
[ "GOC:curators" ]
null
[ "perception of sour taste, detection of chemical stimulus", "perception of sour taste, sensory transduction of chemical stimulus", "sensory detection of chemical stimulus during perception of sour taste", "sensory detection of sour taste", "sensory transduction of chemical stimulus during perception of sour...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0050912" ]
[ "part_of GO:0050915" ]
[ "part_of" ]
[ "GO:0050915" ]
[ "GO:0050912", "GO:0050915" ]
[ "GO:0009593", "part_of GO:0050915" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001582
1,582
detection of chemical stimulus involved in sensory perception of sweet taste
biological_process
The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.
[ "GOC:curators" ]
null
[ "perception of sweet taste, detection of chemical stimulus", "perception of sweet taste, sensory transduction of chemical stimulus", "sensory detection of chemical stimulus during perception of sweet taste", "sensory detection of sweet taste", "sensory transduction of chemical stimulus during perception of ...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0050912" ]
[ "part_of GO:0050916" ]
[ "part_of" ]
[ "GO:0050916" ]
[ "GO:0050912", "GO:0050916" ]
[ "GO:0009593", "part_of GO:0050916" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001583
1,583
obsolete detection of chemical stimulus involved in sensory perception of salty taste
biological_process
OBSOLETE. The series of events required for a salty taste stimulus to be received and converted to a molecular signal.
[ "GOC:curators" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "perception of salty taste, detection of chemical stimulus", "perception of salty taste, sensory transduction of chemical stimulus", "salty taste detection", "sensory detection of chemical stimulus during perception of salty taste", "sensory detection of salty taste", "sensory transduction of chemical sti...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0009593", "GO:0050914" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
6
GO:0001584
1,584
obsolete rhodopsin-like receptor activity
molecular_function
OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor.
[ "GOC:dph", "GOC:mah", "GOC:tb", "IUPHAR_GPCR:1505" ]
This term was made obsolete because it represents a gene product and is named based on protein features.
[ "Class A G protein coupled receptor", "Class A G-protein coupled receptor", "Class A GPCR", "class A orphan receptor activity", "rhodopsin-like receptor activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0001620" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
6
GO:0001586
1,586
Gi/o-coupled serotonin receptor activity
molecular_function
Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.
[ "GOC:mah", "PMID:18571247" ]
null
[ "5-HT1 receptor activity", "serotonin receptor activity, coupled via Gi/o" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004993" ]
[]
[]
[]
[ "GO:0004993" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001587
1,587
Gq/11-coupled serotonin receptor activity
molecular_function
Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
[ "GOC:bf", "GOC:mah", "PMID:18571247", "PMID:18703043" ]
null
[ "5-HT2 receptor activity", "serotonin receptor activity, coupled via Gq/11" ]
[ "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0004993" ]
[]
[]
[]
[ "GO:0004993" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001588
1,588
dopamine neurotransmitter receptor activity, coupled via Gs
molecular_function
Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.
[ "GOC:mah", "ISBN:0953351033", "IUPHAR_RECEPTOR:2252", "IUPHAR_RECEPTOR:2260" ]
null
[ "dopamine D1 receptor activity", "dopamine D5 receptor activity" ]
[ "NARROW", "NARROW" ]
[ "GO:0001589", "GO:0001590" ]
[]
[]
[ "GO:0004952" ]
[]
[]
[]
[ "GO:0004952" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001591
1,591
dopamine neurotransmitter receptor activity, coupled via Gi/Go
molecular_function
Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity.
[ "GOC:mah", "ISBN:0953351033", "IUPHAR_RECEPTOR:2254", "IUPHAR_RECEPTOR:2256", "IUPHAR_RECEPTOR:2258" ]
null
[ "dopamine D2 receptor activity", "dopamine D3 receptor activity", "dopamine D4 receptor activity" ]
[ "NARROW", "NARROW", "NARROW" ]
[ "GO:0001592", "GO:0001593", "GO:0001670" ]
[]
[]
[ "GO:0004952" ]
[]
[]
[]
[ "GO:0004952" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001594
1,594
trace-amine receptor activity
molecular_function
Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.
[ "GOC:mah", "PMID:19325074" ]
null
[]
[]
[]
[]
[]
[ "GO:0008227" ]
[]
[]
[]
[ "GO:0008227" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001596
1,596
angiotensin type I receptor activity
molecular_function
An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.
[ "GOC:mah", "PMID:10977869" ]
null
[ "PLC-activating angiotensin receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001595" ]
[ "part_of GO:0086097" ]
[ "part_of" ]
[ "GO:0086097" ]
[ "GO:0001595", "GO:0086097" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001597
1,597
obsolete apelin-like receptor
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because the function it represents does not exist.
[ "apelin-like receptor", "APJ-like receptor" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0031704" ]
[]
null
null
true
true
9
GO:0001598
1,598
obsolete chemokine receptor-like receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.
[ "chemokine receptor-like receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
4
GO:0001601
1,601
peptide YY receptor activity
molecular_function
Combining with gut peptide YY to initiate a change in cell activity.
[ "PMID:9315606" ]
null
[]
[]
[]
[]
[]
[ "GO:0004983" ]
[]
[]
[]
[ "GO:0004983" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001602
1,602
pancreatic polypeptide receptor activity
molecular_function
Combining with pancreatic polypeptide PP to initiate a change in cell activity.
[ "PMID:9315606" ]
null
[]
[]
[]
[]
[]
[ "GO:0004983" ]
[]
[]
[]
[ "GO:0004983" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001603
1,603
obsolete vasopressin-like receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:curators" ]
null
[ "vasopressin-like receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
2
GO:0001604
1,604
urotensin II receptor activity
molecular_function
Combining with urotensin II to initiate a change in cell activity.
[ "GOC:mah", "PMID:15102493" ]
null
[]
[]
[]
[]
[]
[ "GO:0008528" ]
[]
[]
[]
[ "GO:0008528" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001605
1,605
adrenomedullin receptor activity
molecular_function
Combining with adrenomedullin to initiate a change in cell activity.
[ "GOC:ai" ]
null
[ "G10D receptor" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0097642" ]
[]
[]
[]
[ "GO:0097642" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001606
1,606
obsolete GPR37/endothelin B-like receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.
[ "GPR37/endothelin B-like receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
3
GO:0001608
1,608
G protein-coupled nucleotide receptor activity
molecular_function
Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
[ "GOC:bf", "GOC:dph", "IUPHAR_GPCR:1294" ]
null
[ "G protein coupled nucleotide receptor activity", "G-protein coupled nucleotide receptor activity", "nucleotide receptor activity, G protein coupled", "nucleotide receptor activity, G-protein coupled" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001609
1,609
G protein-coupled adenosine receptor activity
molecular_function
Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
[ "GOC:bf", "GOC:mah", "PMID:9755289" ]
null
[ "A1 adenosine receptor activity, G protein coupled", "A1 adenosine receptor activity, G-protein coupled", "A2A adenosine receptor activity, G protein coupled", "A2A adenosine receptor activity, G-protein coupled", "A2B adenosine receptor activity, G protein coupled", "A2B adenosine receptor activity, G-pr...
[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "BROAD", "EXACT", "EXACT", "NARROW", "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "NARROW", "NARROW", "NARROW", "NARROW", "EXACT" ]
[ "GO:0001610", "GO:0001611", "GO:0001612", "GO:0001613", "GO:0008501" ]
[]
[]
[ "GO:0004930" ]
[ "part_of GO:0001973" ]
[ "part_of" ]
[ "GO:0001973" ]
[ "GO:0001973", "GO:0004930" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001616
1,616
growth hormone secretagogue receptor activity
molecular_function
Combining with ghrelin to initiate a change in cell activity.
[ "GOC:mah", "PMID:17983853" ]
null
[ "ghrelin receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001617
1,617
obsolete growth hormone secretagogue-like receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.
[ "growth hormone secretagogue-like receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
8
GO:0001618
1,618
virus receptor activity
molecular_function
Combining with a virus component and mediating entry of the virus into the cell.
[ "GOC:bf", "GOC:dph", "PMID:7621403", "UniProtKB-KW:KW-1183" ]
null
[ "viral receptor activity" ]
[ "EXACT" ]
[]
[ "goslim_chembl", "goslim_generic" ]
[ "Reactome:R-HSA-9922480 \"Dengue virion gets internalized\"" ]
[ "GO:0140272" ]
[ "part_of GO:0046718" ]
[ "part_of" ]
[ "GO:0046718" ]
[ "GO:0046718", "GO:0140272" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001619
1,619
obsolete lysosphingolipid and lysophosphatidic acid receptor activity
molecular_function
OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity.
[ "GOC:dph" ]
null
[ "lysosphingolipid and lysophosphatidic acid receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0038036", "GO:0070915" ]
[]
null
null
true
true
2
GO:0001621
1,621
G protein-coupled ADP receptor activity
molecular_function
Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
[ "GOC:mah", "GOC:signaling", "PMID:11196645" ]
null
[ "ADP receptor activity", "ADP-activated adenosine receptor activity", "ADP-activated nucleotide receptor activity", "K101 receptor", "platelet ADP receptor activity" ]
[ "BROAD", "RELATED", "BROAD", "NARROW", "NARROW" ]
[ "GO:0045032" ]
[]
[]
[ "GO:0045028" ]
[ "has_part GO:0043531" ]
[ "has_part" ]
[ "GO:0043531" ]
[ "GO:0043531", "GO:0045028" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001626
1,626
nociceptin receptor activity
molecular_function
Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.
[ "GOC:bf", "GOC:mah", "PMID:18670432" ]
null
[ "nociceptin/orphanin-FQ receptor activity", "OFQ receptor activity", "ORPH receptor", "orphanin-FQ receptor activity", "X-opioid receptor activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0004985", "GO:0008528" ]
[]
[]
[]
[ "GO:0004985", "GO:0008528" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23197\" xsd:anyURI" ]
null
null
false
true
4
GO:0001627
1,627
obsolete leucine-rich G-protein receptor-like receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.
[ "leucine-rich G protein receptor-like receptor activity", "leucine-rich G-protein receptor-like receptor activity", "LGR-like receptor" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
7
GO:0001628
1,628
obsolete gastropyloric receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because the gastropyloric receptor is a type of neuron.
[ "gastropyloric receptor activity", "GPR receptor" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
8
GO:0001629
1,629
obsolete G-protein receptor 45-like receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.
[ "G protein receptor 45-like receptor activity", "G-protein receptor 45-like receptor activity", "GPR45-like receptor" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
9
GO:0001631
1,631
cysteinyl leukotriene receptor activity
molecular_function
Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine.
[ "GOC:ai", "ISBN:0198506732" ]
null
[ "CysLT receptor" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0004974" ]
[]
[]
[]
[ "GO:0004974" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001632
1,632
leukotriene B4 receptor activity
molecular_function
Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate.
[ "GOC:ai", "ISBN:0198506732" ]
null
[ "BLT receptor" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0004974" ]
[]
[]
[]
[ "GO:0004974" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001634
1,634
pituitary adenylate cyclase-activating polypeptide receptor activity
molecular_function
A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.
[ "GOC:dph", "GOC:tb" ]
null
[ "PACAP receptor", "pituitary adenylate cyclase activating polypeptide receptor", "pituitary adenylate cyclase activating protein receptor activity", "pituitary adenylate cyclase-activating peptide receptor activity", "pituitary adenylyl cyclase activating protein receptor activity" ]
[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT" ]
[ "GO:0016522" ]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001635
1,635
calcitonin gene-related peptide receptor activity
molecular_function
Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity.
[ "GOC:mah", "PMID:12037140" ]
null
[ "calcitonin gene-related polypeptide receptor activity", "CGRP receptor" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "Wikipedia:CALCRL" ]
[ "GO:0097642" ]
[]
[]
[]
[ "GO:0097642" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001636
1,636
obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity
molecular_function
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.
[ "corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
8
GO:0001637
1,637
G protein-coupled chemoattractant receptor activity
molecular_function
Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
[ "GOC:bf", "GOC:mah" ]
null
[ "G protein chemoattractant receptor activity", "G-protein chemoattractant receptor activity", "G-protein coupled chemoattractant receptor activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001639
1,639
PLC activating G protein-coupled glutamate receptor activity
molecular_function
A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system.
[ "PMID:9016303" ]
null
[ "Group I metabotropic glutamate receptor", "group I metabotropic glutamate receptor activity", "phospholipase C activating metabotropic glutamate receptor activity", "PLC activating G-protein coupled glutamate receptor activity", "PLC activating metabotropic glutamate receptor activity" ]
[ "RELATED", "RELATED", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0098988" ]
[ "part_of GO:0007206" ]
[ "part_of" ]
[ "GO:0007206" ]
[ "GO:0007206", "GO:0098988" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001640
1,640
adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
molecular_function
Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
[ "GOC:bf", "GOC:dph" ]
null
[ "adenylate cyclase inhibiting metabotropic glutamate receptor activity", "adenylyl cyclase inhibiting metabotropic glutamate receptor activity" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0098988" ]
[ "part_of GO:0007196" ]
[ "part_of" ]
[ "GO:0007196" ]
[ "GO:0007196", "GO:0098988" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001641
1,641
group II metabotropic glutamate receptor activity
molecular_function
A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.
[ "GOC:dph" ]
null
[]
[]
[]
[]
[]
[ "GO:0001640" ]
[]
[]
[]
[ "GO:0001640" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001642
1,642
group III metabotropic glutamate receptor activity
molecular_function
A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.
[ "PMID:9016303" ]
null
[]
[]
[]
[]
[]
[ "GO:0001640" ]
[]
[]
[]
[ "GO:0001640" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001646
1,646
cAMP receptor activity
molecular_function
Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
[ "GOC:pg" ]
null
[ "3',5' cAMP receptor activity", "3',5'-cAMP receptor activity", "adenosine 3',5'-cyclophosphate receptor activity", "class E G protein coupled receptor", "class E G-protein coupled receptor", "class E GPCR", "cyclic AMP receptor activity" ]
[ "EXACT", "EXACT", "EXACT", "BROAD", "BROAD", "BROAD", "EXACT" ]
[ "GO:0001644" ]
[]
[]
[ "GO:0045028" ]
[ "has_part GO:0030552" ]
[ "has_part" ]
[ "GO:0030552" ]
[ "GO:0030552", "GO:0045028" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001647
1,647
G protein-coupled cytokinin receptor activity
molecular_function
Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
[ "GOC:bf", "GOC:dph" ]
null
[ "cytokinin receptor activity, G-protein coupled", "G protein coupled cytokinin receptor activity", "G-protein coupled cytokinin receptor activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004930", "GO:0009884" ]
[]
[]
[]
[ "GO:0004930", "GO:0009884" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001649
1,649
osteoblast differentiation
biological_process
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
[ "CL:0000062", "GO_REF:0000034", "GOC:jid" ]
null
[ "osteoblast cell differentiation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030154" ]
[ "part_of GO:0001503" ]
[ "part_of" ]
[ "GO:0001503" ]
[ "GO:0001503", "GO:0030154" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001650
1,650
fibrillar center
cellular_component
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
[ "PMID:10754561" ]
null
[ "fibrillar centre" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005730" ]
[ "part_of" ]
[ "GO:0005730" ]
[ "GO:0005730", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001651
1,651
dense fibrillar component
cellular_component
A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins.
[ "PMID:10754561" ]
null
[ "pars fibrosa" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:sao1841764412" ]
[ "GO:0110165" ]
[ "part_of GO:0005730" ]
[ "part_of" ]
[ "GO:0005730" ]
[ "GO:0005730", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001652
1,652
granular component
cellular_component
A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.
[ "PMID:10754561" ]
null
[ "pars granulosa" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:sao1217793903" ]
[ "GO:0110165" ]
[ "part_of GO:0005730" ]
[ "part_of" ]
[ "GO:0005730" ]
[ "GO:0005730", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001653
1,653
peptide receptor activity
molecular_function
Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
[ "GOC:jl" ]
null
[ "endogenous peptide receptor activity", "exogenous peptide receptor activity" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0038023" ]
[ "has_part GO:0042277" ]
[ "has_part" ]
[ "GO:0042277" ]
[ "GO:0038023", "GO:0042277" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001654
1,654
eye development
biological_process
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
[ "GOC:jid", "GOC:jl" ]
null
[]
[]
[ "GO:0042460" ]
[]
[ "Wikipedia:Eye_development" ]
[ "GO:0007423" ]
[ "part_of GO:0150063" ]
[ "part_of" ]
[ "GO:0150063" ]
[ "GO:0007423", "GO:0150063" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001655
1,655
urogenital system development
biological_process
The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0048731" ]
[ "has_part GO:0072001" ]
[ "has_part" ]
[ "GO:0072001" ]
[ "GO:0048731", "GO:0072001" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22178\" xsd:anyURI" ]
null
null
false
true
9
GO:0001656
1,656
metanephros development
biological_process
The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocr...
[ "GOC:bf", "ISBN:0192800752" ]
null
[]
[]
[]
[]
[]
[ "GO:0001822" ]
[]
[]
[]
[ "GO:0001822" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001657
1,657
ureteric bud development
biological_process
The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0072164" ]
[]
[]
[]
[ "GO:0072164" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001659
1,659
temperature homeostasis
biological_process
A homeostatic process in which an organism modulates its internal body temperature.
[ "GOC:jl" ]
null
[ "thermoregulation" ]
[ "EXACT" ]
[]
[]
[ "Wikipedia:Thermoregulation" ]
[ "GO:0048871" ]
[]
[]
[]
[ "GO:0048871" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001660
1,660
fever generation
biological_process
The heat generation process that results in a rise in body temperature above the normal, often as a response to infection.
[ "GOC:dph", "GOC:jl" ]
null
[ "pyrexia" ]
[ "BROAD" ]
[]
[]
[ "Wikipedia:Fever" ]
[ "GO:0006953", "GO:0031649" ]
[]
[]
[]
[ "GO:0006953", "GO:0031649" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001661
1,661
conditioned taste aversion
biological_process
A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.
[ "GOC:dph", "PMID:9920659" ]
null
[]
[]
[]
[]
[ "Wikipedia:Conditioned_taste_aversion", "Wikipedia:Taste_aversion" ]
[ "GO:0007631", "GO:0008306" ]
[]
[]
[]
[ "GO:0007631", "GO:0008306" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001662
1,662
behavioral fear response
biological_process
An acute behavioral change resulting from a perceived external threat.
[ "GOC:dph", "PMID:9920659" ]
null
[ "behavioural fear response" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002209", "GO:0042596" ]
[]
[]
[]
[ "GO:0002209", "GO:0042596" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31407\" xsd:anyURI" ]
null
null
false
true
2
GO:0001664
1,664
G protein-coupled receptor binding
molecular_function
Binding to a G protein-coupled receptor.
[ "GOC:ceb", "GOC:dph" ]
null
[ "G protein coupled receptor binding", "G protein coupled receptor ligand", "G-protein coupled receptor binding", "G-protein-coupled receptor ligand" ]
[ "EXACT", "NARROW", "EXACT", "NARROW" ]
[]
[]
[ "Reactome:R-HSA-500717 \"Activation of GRIK3 homomer\"" ]
[ "GO:0005102" ]
[]
[]
[]
[ "GO:0005102" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001665
1,665
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
molecular_function
Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.
[ "EC:2.4.3.3" ]
null
[ "GalNAc alpha-2,6-sialyltransferase I activity" ]
[ "RELATED" ]
[]
[]
[ "EC:2.4.3.3", "MetaCyc:2.4.99.3-RXN", "Reactome:R-HSA-4084980 \"ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)\"", "Reactome:R-HSA-9603991 \"ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG\"", "Reactome:R-HSA-9846305 \"ST6GALNAC5,6 transfer Neu5Ac to GM1b\"", "RHEA:11136",...
[ "GO:0008373" ]
[]
[]
[]
[ "GO:0008373" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.3.3", "skos:exactMatch RHEA:11136", "skos:narrowMatch RHEA:81651", "skos:narrowMatch RHEA:81655", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
null
null
false
true
5
GO:0001666
1,666
response to hypoxia
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabo...
[ "GOC:hjd" ]
Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
[ "response to hypoxic stress", "response to intermittent hypoxia", "response to lowered oxygen tension", "response to sustained hypoxia" ]
[ "EXACT", "NARROW", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0006950", "GO:0036293" ]
[]
[]
[]
[ "GO:0006950", "GO:0036293" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001667
1,667
ameboidal-type cell migration
biological_process
Cell migration that is accomplished by extension and retraction of a pseudopodium.
[ "GOC:dph" ]
Note that this term refers to a mode of migration rather than to any particular cell type.
[ "ameboid cell migration", "amoeboid cell migration", "amoeboidal cell migration" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016477" ]
[]
[]
[]
[ "GO:0016477" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001669
1,669
acrosomal vesicle
cellular_component
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
[ "ISBN:0124325653", "ISBN:0198506732" ]
null
[ "acrosomal granule", "acrosome" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "Wikipedia:Acrosome" ]
[ "GO:0030141" ]
[]
[]
[]
[ "GO:0030141" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001671
1,671
ATPase activator activity
molecular_function
Binds to and increases the activity of an ATP hydrolysis activity.
[ "GOC:ajp" ]
null
[ "ATPase stimulator activity" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-5251955 \"HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm\"", "Reactome:R-HSA-5251959 \"HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol\"" ]
[ "GO:0140677" ]
[ "positively_regulates GO:0140657" ]
[ "positively_regulates" ]
[ "GO:0140657" ]
[ "GO:0140657", "GO:0140677" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20955\" xsd:anyURI" ]
null
null
false
true
3
GO:0001673
1,673
male germ cell nucleus
cellular_component
The nucleus of a male germ cell, a reproductive cell in males.
[ "CL:0000015", "GOC:hjd", "GOC:mtg_sensu" ]
null
[ "male germ-cell nucleus" ]
[ "EXACT" ]
[ "GO:0043081" ]
[]
[]
[ "GO:0043073" ]
[]
[]
[]
[ "GO:0043073" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001674
1,674
female germ cell nucleus
cellular_component
The nucleus of the female germ cell, a reproductive cell in females.
[ "CL:0000021", "GOC:hjd" ]
null
[ "female germ-cell nucleus" ]
[ "EXACT" ]
[ "GO:0043080" ]
[]
[]
[ "GO:0043073" ]
[]
[]
[]
[ "GO:0043073" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001675
1,675
acrosome assembly
biological_process
The formation of the acrosome from the spermatid Golgi.
[ "GOC:dph", "GOC:hjd", "GOC:tb" ]
null
[ "acrosome formation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0003006", "GO:0010927", "GO:0022412", "GO:0033363", "GO:0070925" ]
[ "part_of GO:0007286" ]
[ "part_of" ]
[ "GO:0007286" ]
[ "GO:0003006", "GO:0007286", "GO:0010927", "GO:0022412", "GO:0033363", "GO:0070925" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001676
1,676
long-chain fatty acid metabolic process
biological_process
The chemical reactions and pathways involving a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
[ "GOC:ajp" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[ "long-chain fatty acid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006631" ]
[]
[]
[]
[ "GO:0006631" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26445\" xsd:anyURI" ]
null
null
false
true
3
GO:0001677
1,677
formation of translation initiation ternary complex
biological_process
Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
[ "GOC:hjd" ]
null
[ "translation initiation ternary complex assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0022618" ]
[ "part_of GO:0006413" ]
[ "part_of" ]
[ "GO:0006413" ]
[ "GO:0006413", "GO:0022618" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001678
1,678
intracellular glucose homeostasis
biological_process
A homeostatic process involved in the maintenance of a steady state level of glucose within a cell.
[ "GOC:curators", "GOC:dph", "GOC:tb" ]
null
[ "cell glucose homeostasis", "cellular glucose homeostasis" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0042593", "GO:0055082" ]
[]
[]
[]
[ "GO:0042593", "GO:0055082" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001680
1,680
tRNA 3'-terminal CCA addition
biological_process
Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.
[ "GOC:curators", "PMID:2247609" ]
null
[]
[]
[]
[]
[]
[ "GO:0042780" ]
[ "has_part GO:0004810", "has_part GO:0052927", "has_part GO:0052929" ]
[ "has_part", "has_part", "has_part" ]
[ "GO:0004810", "GO:0052927", "GO:0052929" ]
[ "GO:0004810", "GO:0042780", "GO:0052927", "GO:0052929" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19854\" xsd:anyURI" ]
null
null
false
true
3
GO:0001681
1,681
sialate O-acetylesterase activity
molecular_function
Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.
[ "EC:3.1.1.53", "PMID:1991039" ]
null
[ "N-acetylneuraminate acetyltransferase activity" ]
[ "RELATED" ]
[]
[]
[ "EC:3.1.1.53" ]
[ "GO:0008126" ]
[]
[]
[]
[ "GO:0008126" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.1.1.53", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26015\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28526\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
null
null
false
true
2
GO:0001682
1,682
tRNA 5'-leader removal
biological_process
Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
[ "PMID:11592395" ]
null
[ "tRNA 5' leader removal" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0099116" ]
[]
[]
[]
[ "GO:0099116" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001683
1,683
obsolete axonemal dynein heavy chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "axonemal dynein heavy chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005858" ]
[]
[]
null
null
true
true
4
GO:0001684
1,684
obsolete axonemal dynein intermediate chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "axonemal dynein intermediate chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005858" ]
[]
[]
null
null
true
true
3
GO:0001685
1,685
obsolete axonemal dynein intermediate light chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "axonemal dynein intermediate light chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005858" ]
[]
[]
null
null
true
true
8
GO:0001686
1,686
obsolete axonemal dynein light chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "axonemal dynein light chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005858" ]
[]
[]
null
null
true
true
8
GO:0001687
1,687
obsolete cytoplasmic dynein heavy chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "cytoplasmic dynein heavy chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005868" ]
[]
[]
null
null
true
true
9
GO:0001688
1,688
obsolete cytoplasmic dynein intermediate chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "cytoplasmic dynein intermediate chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005868" ]
[]
[]
null
null
true
true
9
GO:0001689
1,689
obsolete cytoplasmic dynein intermediate light chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "cytoplasmic dynein intermediate light chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005868" ]
[]
[]
null
null
true
true
8
GO:0001690
1,690
obsolete cytoplasmic dynein light chain
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "cytoplasmic dynein light chain" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005868" ]
[]
[]
null
null
true
true
4
GO:0001691
1,691
pseudophosphatase activity
molecular_function
Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical a...
[ "GOC:ajp" ]
null
[]
[]
[]
[]
[]
[ "GO:0019212" ]
[]
[]
[]
[ "GO:0019212" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001692
1,692
histamine metabolic process
biological_process
The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
[ "GOC:jl", "ISBN:0395825172" ]
null
[ "histamine metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006576", "GO:0052803" ]
[]
[]
[]
[ "GO:0006576", "GO:0052803" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001694
1,694
histamine biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
[ "GOC:jl", "ISBN:0395825172" ]
null
[ "histamine anabolism", "histamine biosynthesis", "histamine formation", "histamine synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0001693" ]
[]
[]
[ "GO:0001692", "GO:0042401" ]
[]
[]
[]
[ "GO:0001692", "GO:0042401" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001695
1,695
histamine catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
[ "GOC:jl", "ISBN:0395825172" ]
null
[ "histamine breakdown", "histamine catabolism", "histamine degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001692", "GO:0042402", "GO:0052805" ]
[]
[]
[]
[ "GO:0001692", "GO:0042402", "GO:0052805" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001696
1,696
gastric acid secretion
biological_process
The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
[ "GOC:hjd" ]
null
[ "hydrochloric acid secretion" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0022600", "GO:0046717" ]
[]
[]
[]
[ "GO:0022600", "GO:0046717" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001697
1,697
histamine-induced gastric acid secretion
biological_process
The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0001696" ]
[]
[]
[]
[ "GO:0001696" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001698
1,698
gastrin-induced gastric acid secretion
biological_process
The regulated release of gastric acid induced by the interaction of gastrin with its receptor.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0001696" ]
[ "has_part GO:0015054" ]
[ "has_part" ]
[ "GO:0015054" ]
[ "GO:0001696", "GO:0015054" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001699
1,699
acetylcholine-induced gastric acid secretion
biological_process
The regulated release of gastric acid by parietal cells in response to acetylcholine.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0001696" ]
[ "has_part GO:0015464", "part_of GO:1905145" ]
[ "has_part", "part_of" ]
[ "GO:0015464", "GO:1905145" ]
[ "GO:0001696", "GO:0015464", "GO:1905145" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8