LiteFold/GO · Datasets at Hugging Face

GO:0001700

1,700

embryonic development via the syncytial blastoderm

biological_process

The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.

[ "GOC:curators", "GOC:mtg_sensu" ]

null

[]

[ "GO:0009792" ]

[]

[ "GO:0009792" ]

[]

null

false

true

3

GO:0001701

1,701

in utero embryonic development

biological_process

The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.

[ "GOC:curators", "GOC:mtg_sensu" ]

null

[]

[ "GO:0043009" ]

[]

[ "GO:0043009" ]

[]

null

false

true

4

GO:0001702

1,702

gastrulation with mouth forming second

biological_process

A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.

[ "GOC:curators", "GOC:mtg_sensu" ]

null

[ "deuterostomic gastrulation" ]

[ "EXACT" ]

[ "GO:0010003", "GO:0048276" ]

[]

[ "GO:0007369" ]

[]

[ "GO:0007369" ]

[]

null

false

true

7

GO:0001703

1,703

gastrulation with mouth forming first

biological_process

A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.

[ "GOC:curators", "GOC:mtg_sensu" ]

null

[ "protostomic gastrulation" ]

[ "NARROW" ]

[]

[ "GO:0007369" ]

[]

[ "GO:0007369" ]

[]

null

false

true

5

GO:0001705

1,705

ectoderm formation

biological_process

The formation of ectoderm during gastrulation.

[ "GOC:curators" ]

null

[]

[ "GO:0001704" ]

[ "part_of GO:0007398" ]

[ "part_of" ]

[ "GO:0007398" ]

[ "GO:0001704", "GO:0007398" ]

[]

null

false

true

7

GO:0001706

1,706

endoderm formation

biological_process

The formation of the endoderm during gastrulation.

[ "GOC:curators" ]

null

[ "endoblast formation" ]

[ "NARROW" ]

[]

[ "Reactome:R-HSA-9823730 \"Formation of definitive endoderm\"" ]

[ "GO:0001704" ]

[ "part_of GO:0007492" ]

[ "part_of" ]

[ "GO:0007492" ]

[ "GO:0001704", "GO:0007492" ]

[]

null

false

true

2

GO:0001707

1,707

mesoderm formation

biological_process

The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.

[ "GOC:curators" ]

null

[]

[ "GO:0001704" ]

[ "part_of GO:0048332" ]

[ "part_of" ]

[ "GO:0048332" ]

[ "GO:0001704", "GO:0048332" ]

[]

null

false

true

1

GO:0001708

1,708

cell fate specification

biological_process

The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.

[ "GOC:curators" ]

null

[]

[ "GO:0048869" ]

[ "part_of GO:0045165" ]

[ "part_of" ]

[ "GO:0045165" ]

[ "GO:0045165", "GO:0048869" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24390\" xsd:anyURI" ]

null

false

true

7

GO:0001710

1,710

mesodermal cell fate commitment

biological_process

The cell differentiation process that results in commitment of a cell to become part of the mesoderm.

[ "GOC:curators", "ISBN:0878932437" ]

null

[ "mesoderm cell fate commitment" ]

[ "EXACT" ]

[]

[ "GO:0060795" ]

[ "part_of GO:0048333" ]

[ "part_of" ]

[ "GO:0048333" ]

[ "GO:0048333", "GO:0060795" ]

[]

null

false

true

3

GO:0001712

1,712

ectodermal cell fate commitment

biological_process

The cell differentiation process that results in commitment of a cell to become part of the ectoderm.

[ "GOC:curators", "ISBN:0878932437" ]

null

[ "ectoderm cell fate commitment" ]

[ "EXACT" ]

[]

[ "GO:0060795" ]

[ "part_of GO:0001705", "part_of GO:0010668" ]

[ "part_of", "part_of" ]

[ "GO:0001705", "GO:0010668" ]

[ "GO:0001705", "GO:0010668", "GO:0060795" ]

[]

null

false

true

3

GO:0001713

1,713

ectodermal cell fate determination

biological_process

The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.

[ "GOC:curators", "ISBN:0878932437" ]

null

[ "ectoderm cell fate determination" ]

[ "EXACT" ]

[]

[ "GO:0001709" ]

[ "part_of GO:0001712" ]

[ "part_of" ]

[ "GO:0001712" ]

[ "GO:0001709", "GO:0001712" ]

[]

null

false

true

2

GO:0001714

1,714

endodermal cell fate specification

biological_process

The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.

[ "GOC:curators" ]

null

[ "endoderm cell fate specification" ]

[ "EXACT" ]

[]

[ "GO:0001708" ]

[ "part_of GO:0001711" ]

[ "part_of" ]

[ "GO:0001711" ]

[ "GO:0001708", "GO:0001711" ]

[]

null

false

true

9

GO:0001715

1,715

ectodermal cell fate specification

biological_process

The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.

[ "GOC:curators" ]

null

[ "ectoderm cell fate specification" ]

[ "EXACT" ]

[]

[ "GO:0001708" ]

[ "part_of GO:0001712" ]

[ "part_of" ]

[ "GO:0001712" ]

[ "GO:0001708", "GO:0001712" ]

[]

null

false

true

1

GO:0001716

1,716

L-amino-acid oxidase activity

molecular_function

Catalysis of the reaction: an L-alpha-amino acid + H2O + O2 = a 2-oxocarboxylate + H2O2 + NH4+.

[ "RHEA:13781" ]

null

[ "L-amino-acid:oxygen oxidoreductase (deaminating)", "ophio-amino-acid oxidase activity" ]

[ "RELATED", "RELATED" ]

[]

[ "EC:1.4.3.2", "MetaCyc:L-AMINO-ACID-OXIDASE-RXN", "Reactome:R-HSA-2160492 \"IL4I1:FAD oxidises L-Phe to kPPV\"", "RHEA:13781", "RHEA:19025", "RHEA:51404", "RHEA:60996", "RHEA:61224", "RHEA:61228", "RHEA:61232", "RHEA:61236", "RHEA:61244", "RHEA:61248", "RHEA:61252", "RHEA:61256", "RHEA...

[ "GO:0008131" ]

[]

[ "GO:0008131" ]

[]

[ "skos:exactMatch EC:1.4.3.2", "skos:exactMatch RHEA:13781", "skos:narrowMatch RHEA:19025", "skos:narrowMatch RHEA:51404", "skos:narrowMatch RHEA:60996", "skos:narrowMatch RHEA:61224", "skos:narrowMatch RHEA:61228", "skos:narrowMatch RHEA:61232", "skos:narrowMatch RHEA:61236", "skos:narrowMatch RHE...

null

false

true

8

GO:0001717

1,717

conversion of seryl-tRNAsec to selenocys-tRNAsec

biological_process

The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.

[ "ISBN:155581073X" ]

null

[]

[ "GO:0019988" ]

[]

[ "GO:0019988" ]

[]

null

false

true

1

GO:0001720

1,720

conversion of lysyl-tRNA to pyrrolysyl-tRNA

biological_process

The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).

[ "PMID:12029131", "PMID:12029132", "PMID:12121639" ]

null

[]

[ "GO:0019988" ]

[]

[ "GO:0019988" ]

[]

null

false

true

3

GO:0001721

1,721

obsolete intermediate filament associated protein

cellular_component

OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks.

[ "GOC:ajp", "PMID:9484600" ]

This term was made obsolete because it represents a single gene product and not a complex.

[ "IFAP", "intermediate filament associated protein" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0005882" ]

[]

null

true

2

GO:0001722

1,722

obsolete type I intermediate filament associated protein

cellular_component

OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates.

[ "GOC:ajp", "PMID:9484600" ]

This term was made obsolete because it represents a single gene product and not a complex.

[ "type I intermediate filament associated protein" ]

[ "EXACT" ]

[]

[ "GO:0005882" ]

[]

null

true

3

GO:0001723

1,723

obsolete type II intermediate filament associated protein

cellular_component

OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks.

[ "GOC:ajp", "PMID:9484600" ]

This term was made obsolete because it represents a single gene product and not a complex.

[ "type II intermediate filament associated protein" ]

[ "EXACT" ]

[]

[ "GO:0005882" ]

[]

null

true

5

GO:0001724

1,724

obsolete type III intermediate filament associated protein

cellular_component

OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane.

[ "GOC:ajp", "PMID:9484600" ]

This term was made obsolete because it represents a single gene product and not a complex.

[ "type III intermediate filament associated protein" ]

[ "EXACT" ]

[]

[ "GO:0045098" ]

[]

null

true

4

GO:0001725

1,725

stress fiber

cellular_component

A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.

[ "PMID:16651381" ]

null

[ "actin cable", "stress fibre" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0042641", "GO:0097517" ]

[]

[ "GO:0042641", "GO:0097517" ]

[]

null

false

true

1

GO:0001729

1,729

ceramide kinase activity

molecular_function

Catalysis of the reaction: an N-acylsphing-4-enine + ATP = ADP + an N-acylsphing-4-enine 1-phosphate + H+.

[ "EC:2.7.1.138" ]

null

[ "acylsphingosine kinase activity", "ATP:ceramide 1-phosphotransferase activity" ]

[ "RELATED", "RELATED" ]

[]

[ "EC:2.7.1.138", "MetaCyc:CERAMIDE-KINASE-RXN", "Reactome:R-HSA-1638845 \"CERK phosphorylates CERA to form C1P\"", "RHEA:17929", "RHEA:43312", "RHEA:46340", "RHEA:47904" ]

[ "GO:0001727" ]

[]

[ "GO:0001727" ]

[]

[ "skos:exactMatch EC:2.7.1.138", "skos:exactMatch RHEA:17929", "skos:narrowMatch RHEA:43312", "skos:narrowMatch RHEA:46340", "skos:narrowMatch RHEA:47904", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

7

GO:0001730

1,730

2'-5'-oligoadenylate synthetase activity

molecular_function

Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.

[ "ISBN:0198506732" ]

null

[ "(2-5')oligo(A) synthetase activity", "2'-5' oligoadenylate synthetase activity", "2-5A synthetase activity", "oligo-2',5'-adenylate synthetase activity" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "EC:2.7.7.84", "MetaCyc:RXN-13648", "Reactome:R-HSA-8983680 \"OAS1 produces oligoadenylates\"", "Reactome:R-HSA-8985091 \"OAS3 produces oligoadenylates\"", "Reactome:R-HSA-8985104 \"OAS2 produces oligoadenylates\"", "RHEA:34407" ]

[ "GO:0070566" ]

[]

[ "GO:0070566" ]

[]

[ "skos:exactMatch EC:2.7.7.84", "skos:exactMatch RHEA:34407", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

5

GO:0001731

1,731

formation of translation preinitiation complex

biological_process

The joining of the small ribosomal subunit, ternary complex, and mRNA.

[ "GOC:hjd" ]

See also the cellular component terms 'eukaryotic 43S preinitiation complex ; GO:0016282', 'eukaryotic 48S initiation complex ; GO:0033290', and their children.

[ "formation of translation pre-initiation complex", "translation preinitiation complex assembly" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0022618" ]

[ "part_of GO:0002183" ]

[ "part_of" ]

[ "GO:0002183" ]

[ "GO:0002183", "GO:0022618" ]

[]

null

false

true

8

GO:0001732

1,732

formation of cytoplasmic translation initiation complex

biological_process

Joining of the large ribosomal subunit with the translation preinitiation complex, with release of IF2/eIF2 and IF3/eIF3 or IF5B/eIF5B. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.

[ "GOC:hjd", "PMID:29735639" ]

null

[ "cytoplasmic translation initiation complex assembly", "formation of translation initiation complex", "translation initiation complex assembly" ]

[ "EXACT", "BROAD", "BROAD" ]

[]

[ "GO:0022618" ]

[ "part_of GO:0002183" ]

[ "part_of" ]

[ "GO:0002183" ]

[ "GO:0002183", "GO:0022618" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11517\" xsd:anyURI" ]

null

false

true

7

GO:0001733

1,733

galactosylceramide sulfotransferase activity

molecular_function

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.

[ "EC:2.8.2.11", "PMID:10727929", "RHEA:20613" ]

null

[ "3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity", "3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity", "cerebroside sulfotransferase activity", "galactocerebroside sulfotransferase activity", "galactolipid sulfotransferase activity", "galactosylceramid...

[ "RELATED", "RELATED", "EXACT", "RELATED", "RELATED", "EXACT", "RELATED", "RELATED", "RELATED" ]

[]

[ "EC:2.8.2.11", "MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN", "Reactome:R-HSA-9844587 \"GAL3ST1 transfers sulfate to GalCer,LacCer\"", "RHEA:20613", "RHEA:41744", "RHEA:43304" ]

[ "GO:0050694" ]

[]

[ "GO:0050694" ]

[]

[ "skos:exactMatch EC:2.8.2.11", "skos:exactMatch RHEA:20613", "skos:narrowMatch RHEA:41744", "skos:narrowMatch RHEA:43304", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

3

GO:0001734

1,734

mRNA m(6)A methyltransferase activity

molecular_function

Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.

[ "EC:2.1.1.348", "GOC:hjd" ]

null

[ "mRNA (N6-adenosine)-methyltransferase activity" ]

[ "EXACT" ]

[]

[ "EC:2.1.1.348", "MetaCyc:RXN-19346", "Reactome:R-HSA-72095 \"Internal Methylation of mRNA\"", "RHEA:55584" ]

[ "GO:0008174" ]

[]

[ "GO:0008174" ]

[]

[ "skos:exactMatch EC:2.1.1.348", "skos:exactMatch RHEA:55584", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

3

GO:0001735

1,735

prenylcysteine oxidase activity

molecular_function

Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.

[ "GOC:hjd", "RHEA:53892" ]

null

[ "prenylcysteine lyase activity", "S-prenyl-L-cysteine:oxygen oxidoreductase activity" ]

[ "RELATED", "RELATED" ]

[]

[ "EC:1.8.3.5", "MetaCyc:RXN-18932", "RHEA:53892", "RHEA:70407" ]

[ "GO:0016670" ]

[]

[ "GO:0016670" ]

[]

[ "skos:exactMatch EC:1.8.3.5", "skos:exactMatch RHEA:53892", "skos:narrowMatch RHEA:70407", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

2

GO:0001736

1,736

establishment of planar polarity

biological_process

Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.

[ "GOC:dph" ]

null

[ "establishment of planar cell polarity" ]

[ "NARROW" ]

[]

[ "GO:0007164" ]

[ "part_of GO:0001738" ]

[ "part_of" ]

[ "GO:0001738" ]

[ "GO:0001738", "GO:0007164" ]

[]

null

false

true

7

GO:0001737

1,737

establishment of imaginal disc-derived wing hair orientation

biological_process

Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.

[ "GOC:ascb_2009", "GOC:dph", "GOC:mtg_sensu", "GOC:tb", "PMID:11239465" ]

null

[ "establishment of wing hair orientation" ]

[ "EXACT" ]

[]

[ "GO:0001736", "GO:0009886" ]

[ "part_of GO:0035317" ]

[ "part_of" ]

[ "GO:0035317" ]

[ "GO:0001736", "GO:0009886", "GO:0035317" ]

[]

null

false

true

4

GO:0001738

1,738

morphogenesis of a polarized epithelium

biological_process

The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.

[ "GOC:dph" ]

null

[ "epithelial polarization" ]

[ "EXACT" ]

[]

[ "GO:0002009" ]

[]

[ "GO:0002009" ]

[]

null

false

true

7

GO:0001739

1,739

sex chromatin

cellular_component

Chromatin that is part of a sex chromosome.

[ "GOC:dos", "ISBN:0198506732" ]

null

[]

[ "GO:0000792" ]

[ "part_of GO:0000803" ]

[ "part_of" ]

[ "GO:0000803" ]

[ "GO:0000792", "GO:0000803" ]

[ "GO:0000792", "part_of GO:0000803" ]

[]

null

false

true

7

GO:0001740

1,740

Barr body

cellular_component

A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.

[ "GOC:hjd", "GOC:mr", "NIF_Subcellular:sao1571698684" ]

null

[]

[ "NIF_Subcellular:sao1571698684", "Wikipedia:Barr_body" ]

[ "GO:0000228", "GO:0000805" ]

[ "has_part GO:0098578" ]

[ "has_part" ]

[ "GO:0098578" ]

[ "GO:0000228", "GO:0000805", "GO:0098578" ]

[]

null

false

true

7

GO:0001741

1,741

XY body

cellular_component

A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.

[ "GOC:hjd", "GOC:mr", "PMID:20622855", "Wikipedia:XY_sex-determination_system" ]

null

[]

[ "GO:0000803" ]

[ "has_part GO:0098578" ]

[ "has_part" ]

[ "GO:0098578" ]

[ "GO:0000803", "GO:0098578" ]

[]

null

false

true

4

GO:0001742

1,742

oenocyte differentiation

biological_process

The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.

[ "GOC:curators" ]

null

[ "oenocyte cell differentiation" ]

[ "EXACT" ]

[]

[ "GO:0030154" ]

[]

[ "GO:0030154" ]

[]

null

false

true

4

GO:0001743

1,743

lens placode formation

biological_process

The initial developmental process that will lead to the formation of an eye.

[ "GOC:dph" ]

null

[ "optic placode formation" ]

[ "RELATED" ]

[]

[ "GO:0060788" ]

[ "part_of GO:0048598" ]

[ "part_of" ]

[ "GO:0048598" ]

[ "GO:0048598", "GO:0060788" ]

[]

null

false

true

5

GO:0001744

1,744

insect visual primordium formation

biological_process

Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.

[ "GOC:mtg_sensu", "PMID:8402833" ]

null

[ "optic lobe and Bolwig's organ precursor formation", "optic lobe placode formation" ]

[ "EXACT", "EXACT" ]

[ "GO:0007457" ]

[]

[ "GO:0060788" ]

[ "part_of GO:0001748" ]

[ "part_of" ]

[ "GO:0001748" ]

[ "GO:0001748", "GO:0060788" ]

[]

null

false

true

4

GO:0001745

1,745

compound eye morphogenesis

biological_process

The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila ...

[ "GOC:dph", "GOC:mtg_sensu" ]

null

[ "insect-type retina morphogenesis" ]

[ "EXACT" ]

[]

[ "GO:0048592" ]

[ "part_of GO:0048749" ]

[ "part_of" ]

[ "GO:0048749" ]

[ "GO:0048592", "GO:0048749" ]

[]

null

false

true

9

GO:0001746

1,746

Bolwig's organ morphogenesis

biological_process

The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to ...

[ "PMID:6185380" ]

null

[]

[ "GO:0048592" ]

[ "part_of GO:0055034" ]

[ "part_of" ]

[ "GO:0055034" ]

[ "GO:0048592", "GO:0055034" ]

[]

null

false

true

7

GO:0001748

1,748

insect visual primordium development

biological_process

The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis...

[ "GOC:mtg_sensu", "PMID:8402833" ]

null

[ "optic lobe and Bolwig's organ precursor development", "optic lobe placode development", "optic placode development" ]

[ "EXACT", "EXACT", "BROAD" ]

[ "GO:0048049" ]

[]

[ "GO:0048856" ]

[]

[ "GO:0048856" ]

[]

null

false

true

8

GO:0001750

1,750

photoreceptor outer segment

cellular_component

The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.

[ "GOC:cilia", "GOC:krc", "GOC:pde", "ISBN:0824072820", "PMID:19501669", "PMID:26574505", "PMID:6771304" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0097733" ]

[ "part_of" ]

[ "GO:0097733" ]

[ "GO:0097733", "GO:0110165" ]

[]

null

false

true

3

GO:0001751

1,751

compound eye photoreceptor cell differentiation

biological_process

The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.

[ "GOC:curators" ]

null

[]

[ "GO:0001754" ]

[ "part_of GO:0001745" ]

[ "part_of" ]

[ "GO:0001745" ]

[ "GO:0001745", "GO:0001754" ]

[]

null

false

true

4

GO:0001752

1,752

compound eye photoreceptor fate commitment

biological_process

The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different ph...

[ "GOC:mtg_sensu" ]

null

[]

[ "GO:0007459" ]

[]

[ "GO:0042706" ]

[ "part_of GO:0001751" ]

[ "part_of" ]

[ "GO:0001751" ]

[ "GO:0001751", "GO:0042706" ]

[]

null

false

true

5

GO:0001753

1,753

obsolete adult eye photoreceptor development (sensu Drosophila)

biological_process

OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye.

[ "GOC:curators" ]

This term was made obsolete because eye photoreceptors have completed their development by the time the adult phase begins.

[ "adult eye photoreceptor development (sensu Drosophila)" ]

[ "EXACT" ]

[]

[ "GO:0042051" ]

[]

null

true

2

GO:0001754

1,754

eye photoreceptor cell differentiation

biological_process

The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.

[ "GOC:curators" ]

null

[]

[ "GO:0046530" ]

[ "part_of GO:0048592" ]

[ "part_of" ]

[ "GO:0048592" ]

[ "GO:0046530", "GO:0048592" ]

[]

null

false

true

7

GO:0001755

1,755

neural crest cell migration

biological_process

The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.

[ "GOC:ascb_2009", "GOC:dph", "GOC:tb", "ISBN:0878932437" ]

null

[]

[ "GO:0090497" ]

[ "part_of GO:0014032" ]

[ "part_of" ]

[ "GO:0014032" ]

[ "GO:0014032", "GO:0090497" ]

[]

null

false

true

9

GO:0001756

1,756

somitogenesis

biological_process

The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.

[ "ISBN:0721662544" ]

null

[ "formation of mesodermal clusters" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-9824272 \"Somitogenesis\"", "Wikipedia:Somitogenesis" ]

[ "GO:0009952", "GO:0035282", "GO:0048646" ]

[ "part_of GO:0043009", "part_of GO:0061053" ]

[ "part_of", "part_of" ]

[ "GO:0043009", "GO:0061053" ]

[ "GO:0009952", "GO:0035282", "GO:0043009", "GO:0048646", "GO:0061053" ]

[]

null

false

true

5

GO:0001757

1,757

somite specification

biological_process

The process in which individual somites establish identity during embryogenesis.

[ "GOC:dph" ]

null

[]

[ "GO:0007379", "GO:0009880" ]

[ "part_of GO:0001756" ]

[ "part_of" ]

[ "GO:0001756" ]

[ "GO:0001756", "GO:0007379", "GO:0009880" ]

[]

null

false

true

8

GO:0001758

1,758

retinal dehydrogenase (NAD+) activity

molecular_function

Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.

[ "EC:1.2.1.36" ]

null

[ "cytosolic retinal dehydrogenase activity", "retinal dehydrogenase activity", "retinal:NAD+ oxidoreductase activity" ]

[ "RELATED", "BROAD", "RELATED" ]

[]

[ "EC:1.2.1.36", "MetaCyc:RETINAL-DEHYDROGENASE-RXN", "Reactome:R-HSA-5362522 \"ALDHs oxidise atRAL to atRA\"", "Reactome:R-HSA-5696101 \"ALDH8A1 oxidises 9cRAL to 9cRA\"", "RHEA:16177", "RHEA:42080", "RHEA:42084", "RHEA:47132", "RHEA:67332" ]

[ "GO:0004029" ]

[]

[ "GO:0004029" ]

[]

[ "skos:exactMatch EC:1.2.1.36", "skos:exactMatch RHEA:16177", "skos:narrowMatch RHEA:42080", "skos:narrowMatch RHEA:42084", "skos:narrowMatch RHEA:47132", "skos:narrowMatch RHEA:67332", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI", "term_tracker_item \"htt...

null

false

true

1

GO:0001759

1,759

organ induction

biological_process

The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.

[ "ISBN:0878932437" ]

null

[ "induction of an organ" ]

[ "EXACT" ]

[]

[ "GO:0003156", "GO:0031128", "GO:0110110" ]

[ "positively_regulates GO:0010092" ]

[ "positively_regulates" ]

[ "GO:0010092" ]

[ "GO:0003156", "GO:0010092", "GO:0031128", "GO:0110110" ]

[]

null

false

true

3

GO:0001760

1,760

aminocarboxymuconate-semialdehyde decarboxylase activity

molecular_function

Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H+ = 2-aminomuconate 6-semialdehyde + CO2.

[ "EC:4.1.1.45", "RHEA:16557" ]

null

[ "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)", "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity", "2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity", "ACMSD activity", "alpha-amino-beta-carboxymuconate-epsilon-se...

[ "RELATED", "RELATED", "RELATED", "EXACT", "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "EC:4.1.1.45", "KEGG_REACTION:R04323", "MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN", "RHEA:16557" ]

[ "GO:0016831" ]

[]

[ "GO:0016831" ]

[]

[ "skos:exactMatch EC:4.1.1.45", "skos:exactMatch RHEA:16557", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

3

GO:0001761

1,761

beta-alanine transmembrane transporter activity

molecular_function

Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.

[ "GOC:hjd" ]

null

[ "beta-alanine transporter activity" ]

[ "BROAD" ]

[]

[ "GO:0015175", "GO:0046943" ]

[ "part_of GO:0001762" ]

[ "part_of" ]

[ "GO:0001762" ]

[ "GO:0001762", "GO:0015175", "GO:0046943" ]

[]

null

false

true

5

GO:0001762

1,762

beta-alanine transport

biological_process

The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

[ "GOC:hjd" ]

null

[]

[ "GO:0015804", "GO:0046942", "GO:0071705" ]

[]

[ "GO:0015804", "GO:0046942", "GO:0071705" ]

[]

null

false

true

2

GO:0001763

1,763

morphogenesis of a branching structure

biological_process

The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.

[ "ISBN:0721662544" ]

null

[ "branching morphogenesis" ]

[ "EXACT" ]

[]

[ "GO:0009653", "GO:0032501" ]

[]

[ "GO:0009653", "GO:0032501" ]

[]

null

false

true

7

GO:0001764

1,764

neuron migration

biological_process

The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.

[ "CL:0000540", "GOC:curators" ]

null

[ "neuron chemotaxis", "neuron guidance", "neuronal migration" ]

[ "EXACT", "RELATED", "EXACT" ]

[]

[ "Wikipedia:Neural_development#Neuron_migration", "Wikipedia:Neuron_migration" ]

[ "GO:0016477" ]

[ "part_of GO:0048699" ]

[ "part_of" ]

[ "GO:0048699" ]

[ "GO:0016477", "GO:0048699" ]

[]

null

false

true

1

GO:0001765

1,765

membrane raft assembly

biological_process

The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.

[ "PMID:12648772", "PMID:12803918", "PMID:16645198" ]

null

[ "lipid raft assembly", "lipid raft formation", "membrane raft formation" ]

[ "EXACT", "RELATED", "RELATED" ]

[]

[ "GO:0031579", "GO:0071709" ]

[]

[ "GO:0031579", "GO:0071709" ]

[]

null

false

true

6

GO:0001766

1,766

membrane raft polarization

biological_process

The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.

[ "PMID:12615889" ]

null

[ "lipid raft polarization", "membrane polarization" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0031580" ]

[]

[ "GO:0031580" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20666\" xsd:anyURI" ]

null

false

true

9

GO:0001767

1,767

establishment of lymphocyte polarity

biological_process

The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.

[ "GOC:mgi_curators", "PMID:11244041", "PMID:12615889" ]

null

[ "lymphocyte polarization" ]

[ "EXACT" ]

[]

[ "GO:0030010" ]

[ "part_of GO:0046649" ]

[ "part_of" ]

[ "GO:0046649" ]

[ "GO:0030010", "GO:0046649" ]

[]

null

false

true

7

GO:0001768

1,768

establishment of T cell polarity

biological_process

The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.

[ "GOC:mgi_curators", "PMID:11244041", "PMID:12615889" ]

null

[ "establishment of T lymphocyte polarity", "establishment of T-cell polarity", "establishment of T-lymphocyte polarity", "T cell polarization", "T lymphocyte polarization", "T-cell polarization" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001767" ]

[ "part_of GO:0042110" ]

[ "part_of" ]

[ "GO:0042110" ]

[ "GO:0001767", "GO:0042110" ]

[]

null

false

true

9

GO:0001769

1,769

establishment of B cell polarity

biological_process

The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.

[ "GOC:mgi_curators", "PMID:12615889", "PMID:9692889" ]

Note that 'antigen displaying cell' in this term encompasses cell types such as follicular dendritic cells which display the unprocessed antigens of a B cell, leading to activation of the B cells and antigen uptake and processing by the B cells.

[ "B cell polarization", "B lymphocyte polarization", "B-cell polarization", "establishment of B lymphocyte polarity", "establishment of B-cell polarity", "establishment of B-lymphocyte polarity" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001767" ]

[ "part_of GO:0042113" ]

[ "part_of" ]

[ "GO:0042113" ]

[ "GO:0001767", "GO:0042113" ]

[]

null

false

true

9

GO:0001770

1,770

establishment of natural killer cell polarity

biological_process

The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.

[ "GOC:mgi_curators", "PMID:12615886", "PMID:9759849" ]

null

[ "establishment of NK cell polarity", "natural killer cell polarization", "NK cell polarization" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001767" ]

[ "part_of GO:0030101" ]

[ "part_of" ]

[ "GO:0030101" ]

[ "GO:0001767", "GO:0030101" ]

[]

null

false

true

5

GO:0001771

1,771

immunological synapse formation

biological_process

The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of ...

[ "GOC:mgi_curators", "PMID:11244041", "PMID:11376330" ]

null

[ "formation of immunological synapse" ]

[ "EXACT" ]

[]

[ "GO:0009988" ]

[ "part_of GO:0046649" ]

[ "part_of" ]

[ "GO:0046649" ]

[ "GO:0009988", "GO:0046649" ]

[]

null

false

true

2

GO:0001774

1,774

microglial cell activation

biological_process

The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.

[ "GOC:mgi_curators", "PMID:10626665", "PMID:10695728", "PMID:12580336", "PMID:9893949" ]

null

[]

[ "GO:0002269", "GO:0042116", "GO:0061900" ]

[]

[ "GO:0002269", "GO:0042116", "GO:0061900" ]

[]

null

false

true

1

GO:0001776

1,776

leukocyte homeostasis

biological_process

The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.

[ "GOC:add", "ISBN:0781735149" ]

Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus.

[ "immune cell homeostasis", "leucocyte homeostasis" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0002376", "GO:0048872" ]

[]

[ "GO:0002376", "GO:0048872" ]

[]

null

false

true

1

GO:0001777

1,777

T cell homeostatic proliferation

biological_process

The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.

[ "GOC:mgi_curators", "ISBN:0781735149" ]

null

[ "resting T cell proliferation", "resting T-cell proliferation", "T lymphocyte homeostatic proliferation", "T-cell homeostatic proliferation", "T-lymphocyte homeostatic proliferation" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0042098" ]

[ "part_of GO:0043029" ]

[ "part_of" ]

[ "GO:0043029" ]

[ "GO:0042098", "GO:0043029" ]

[]

null

false

true

1

GO:0001779

1,779

natural killer cell differentiation

biological_process

The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.

[ "GOC:add", "ISBN:0781735149" ]

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

[ "natural killer cell development", "NK cell differentiation" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0030098", "GO:0030101" ]

[]

[ "GO:0030098", "GO:0030101" ]

[]

null

false

true

5

GO:0001780

1,780

neutrophil homeostasis

biological_process

The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.

[ "GOC:add", "GOC:pr", "PMID:12752675", "PMID:12960266" ]

Note that this term represents the return of neutrophil levels to stable numbers following an immune response as well as the proliferation and elimination of neutrophils required to maintain stable numbers in the absence of an outside stimulus.

[]

[ "GO:0001776", "GO:0002262" ]

[]

[ "GO:0001776", "GO:0002262" ]

[]

null

false

true

9

GO:0001781

1,781

neutrophil apoptotic process

biological_process

Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.

[ "CL:0000775", "GOC:add", "GOC:mtg_apoptosis", "PMID:12752675", "PMID:12960266" ]

null

[ "apoptosis of neutrophils", "neutrophil apoptosis", "neutrophil programmed cell death by apoptosis", "programmed cell death of neutrophils by apoptosis", "programmed cell death, neutrophils" ]

[ "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006925", "GO:0033028", "GO:0071887" ]

[ "part_of GO:0001780" ]

[ "part_of" ]

[ "GO:0001780" ]

[ "GO:0001780", "GO:0006925", "GO:0033028", "GO:0071887" ]

[]

null

false

true

2

GO:0001782

1,782

B cell homeostasis

biological_process

The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

[ "GOC:add", "ISBN:0781735149", "PMID:12956429" ]

Note that this term represents the return of B cell levels to stable numbers following an immune response as well as the proliferation and elimination of B cells required to maintain stable numbers in the absence of an outside stimulus.

[ "B lymphocyte homeostasis", "B-cell homeostasis", "B-lymphocyte homeostasis" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0002260" ]

[]

[ "GO:0002260" ]

[]

null

false

true

5

GO:0001783

1,783

B cell apoptotic process

biological_process

Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.

[ "CL:0000236", "GOC:add", "GOC:mtg_apoptosis", "ISBN:0781735149" ]

null

[ "apoptosis of B cells", "apoptosis of B lymphocytes", "apoptosis of B-cells", "apoptosis of B-lymphocytes", "B cell apoptosis", "B cell programmed cell death by apoptosis", "B lymphocyte apoptosis", "B lymphocyte programmed cell death by apoptosis", "B-cell apoptosis", "B-cell programmed cell deat...

[ "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0070227" ]

[]

[ "GO:0070227" ]

[]

null

false

true

8

GO:0001784

1,784

phosphotyrosine residue binding

molecular_function

Binding to a phosphorylated tyrosine residue within a protein.

[ "PMID:14636584" ]

null

[ "phosphotyrosine binding" ]

[ "RELATED" ]

[]

[ "GO:0045309" ]

[]

[ "GO:0045309" ]

[]

null

false

true

8

GO:0001785

1,785

prostaglandin J receptor activity

molecular_function

Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.

[ "PMID:12878180" ]

null

[ "PGJ receptor activity", "PGJ(2) receptor activity" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0004955" ]

[]

[ "GO:0004955" ]

[]

null

false

true

5

GO:0001786

1,786

phosphatidylserine binding

molecular_function

Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.

[ "ISBN:0198506732", "PMID:12000961" ]

null

[]

[ "GO:0005543", "GO:0043168", "GO:0072341" ]

[]

[ "GO:0005543", "GO:0043168", "GO:0072341" ]

[]

null

false

true

1

GO:0001787

1,787

natural killer cell proliferation

biological_process

The expansion of a natural killer cell population by cell division.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "NK cell proliferation" ]

[ "EXACT" ]

[]

[ "GO:0030101", "GO:0046651" ]

[]

[ "GO:0030101", "GO:0046651" ]

[]

null

false

true

6

GO:0001788

1,788

antibody-dependent cellular cytotoxicity

biological_process

Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.

[ "GOC:pr", "ISBN:0781735149", "PMID:11677095", "PMID:9581795" ]

null

[ "ADCC", "antibody dependent cell death", "antibody dependent cell killing", "antibody-dependent cell death", "antibody-dependent cell killing", "type VI hypersensitivity" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity", "Wikipedia:Antibody-dependent_cellular_cytotoxicity" ]

[ "GO:0001794", "GO:0001909" ]

[]

[ "GO:0001794", "GO:0001909" ]

[]

null

false

true

2

GO:0001790

1,790

polymeric immunoglobulin binding

molecular_function

Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0019865" ]

[]

[ "GO:0019865" ]

[]

null

false

true

6

GO:0001791

1,791

IgM binding

molecular_function

Binding to an immunoglobulin of the IgM isotype.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0019865" ]

[]

[ "GO:0019865" ]

[]

null

false

true

2

GO:0001792

1,792

polymeric immunoglobulin receptor activity

molecular_function

Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0019763" ]

[ "has_part GO:0001790" ]

[ "has_part" ]

[ "GO:0001790" ]

[ "GO:0001790", "GO:0019763" ]

[]

null

false

true

3

GO:0001793

1,793

IgM receptor activity

molecular_function

Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling", "ISBN:0781735149" ]

null

[]

[ "GO:0019763" ]

[ "has_part GO:0001791" ]

[ "has_part" ]

[ "GO:0001791" ]

[ "GO:0001791", "GO:0019763" ]

[]

null

false

true

1

GO:0001794

1,794

type IIa hypersensitivity

biological_process

An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.

[ "GOC:add", "ISBN:0781735149" ]

Note that some type IIb hypersensitivity responses (GO:0001795) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIa hypersensitivity.

[]

[ "GO:0002445" ]

[]

[ "GO:0002445" ]

[]

null

false

true

9

GO:0001795

1,795

type IIb hypersensitivity

biological_process

An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors.

[ "GOC:add", "ISBN:0781735149" ]

Note that some type IIa hypersensitivity response (GO:0001794) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIb hypersensitivity.

[ "type V hypersensitivity" ]

[ "EXACT" ]

[]

[ "GO:0002445" ]

[]

[ "GO:0002445" ]

[]

null

false

true

1

GO:0001797

1,797

negative regulation of type IIa hypersensitivity

biological_process

Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "down regulation of type IIa hypersensitivity", "down-regulation of type IIa hypersensitivity", "downregulation of type IIa hypersensitivity", "inhibition of type IIa hypersensitivity" ]

[ "EXACT", "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0001796", "GO:0002893" ]

[ "negatively_regulates GO:0001794" ]

[ "negatively_regulates" ]

[ "GO:0001794" ]

[ "GO:0001794", "GO:0001796", "GO:0002893" ]

[ "GO:0065007", "negatively_regulates GO:0001794" ]

[]

null

false

true

3

GO:0001798

1,798

positive regulation of type IIa hypersensitivity

biological_process

Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of type IIa hypersensitivity", "stimulation of type IIa hypersensitivity", "up regulation of type IIa hypersensitivity", "up-regulation of type IIa hypersensitivity", "upregulation of type IIa hypersensitivity" ]

[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001796", "GO:0002894" ]

[ "positively_regulates GO:0001794" ]

[ "positively_regulates" ]

[ "GO:0001794" ]

[ "GO:0001794", "GO:0001796", "GO:0002894" ]

[ "GO:0065007", "positively_regulates GO:0001794" ]

[]

null

false

true

5

GO:0001799

1,799

regulation of type IIb hypersensitivity

biological_process

Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0002892" ]

[ "regulates GO:0001795" ]

[ "regulates" ]

[ "GO:0001795" ]

[ "GO:0001795", "GO:0002892" ]

[ "GO:0065007", "regulates GO:0001795" ]

[]

null

false

true

6

GO:0001800

1,800

negative regulation of type IIb hypersensitivity

biological_process

Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "down regulation of type IIb hypersensitivity", "down-regulation of type IIb hypersensitivity", "downregulation of type IIb hypersensitivity", "inhibition of type IIb hypersensitivity" ]

[ "EXACT", "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0001799", "GO:0002893" ]

[ "negatively_regulates GO:0001795" ]

[ "negatively_regulates" ]

[ "GO:0001795" ]

[ "GO:0001795", "GO:0001799", "GO:0002893" ]

[ "GO:0065007", "negatively_regulates GO:0001795" ]

[]

null

false

true

3

GO:0001801

1,801

positive regulation of type IIb hypersensitivity

biological_process

Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of type IIb hypersensitivity", "stimulation of type IIb hypersensitivity", "up regulation of type IIb hypersensitivity", "up-regulation of type IIb hypersensitivity", "upregulation of type IIb hypersensitivity" ]

[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001799", "GO:0002894" ]

[ "positively_regulates GO:0001795" ]

[ "positively_regulates" ]

[ "GO:0001795" ]

[ "GO:0001795", "GO:0001799", "GO:0002894" ]

[ "GO:0065007", "positively_regulates GO:0001795" ]

[]

null

false

true

7

GO:0001802

1,802

type III hypersensitivity

biological_process

An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.

[ "GOC:add", "ISBN:0781735149" ]

Note that the Arthus reaction is an example of type III hypersensitivity.

[]

[ "Wikipedia:Type_III_hypersensitivity" ]

[ "GO:0002444", "GO:0002524", "GO:0016064" ]

[]

[ "GO:0002444", "GO:0002524", "GO:0016064" ]

[]

null

false

true

5

GO:0001803

1,803

regulation of type III hypersensitivity

biological_process

Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0002883", "GO:0002886", "GO:0002889" ]

[ "regulates GO:0001802" ]

[ "regulates" ]

[ "GO:0001802" ]

[ "GO:0001802", "GO:0002883", "GO:0002886", "GO:0002889" ]

[ "GO:0065007", "regulates GO:0001802" ]

[]

null

false

true

1

GO:0001804

1,804

negative regulation of type III hypersensitivity

biological_process

Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "down regulation of type III hypersensitivity", "down-regulation of type III hypersensitivity", "downregulation of type III hypersensitivity", "inhibition of type III hypersensitivity" ]

[ "EXACT", "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0001803", "GO:0002884", "GO:0002887", "GO:0002890" ]

[ "negatively_regulates GO:0001802" ]

[ "negatively_regulates" ]

[ "GO:0001802" ]

[ "GO:0001802", "GO:0001803", "GO:0002884", "GO:0002887", "GO:0002890" ]

[ "GO:0065007", "negatively_regulates GO:0001802" ]

[]

null

false

true

2

GO:0001805

1,805

positive regulation of type III hypersensitivity

biological_process

Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of type III hypersensitivity", "stimulation of type III hypersensitivity", "up regulation of type III hypersensitivity", "up-regulation of type III hypersensitivity", "upregulation of type III hypersensitivity" ]

[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001803", "GO:0002885", "GO:0002888", "GO:0002891" ]

[ "positively_regulates GO:0001802" ]

[ "positively_regulates" ]

[ "GO:0001802" ]

[ "GO:0001802", "GO:0001803", "GO:0002885", "GO:0002888", "GO:0002891" ]

[ "GO:0065007", "positively_regulates GO:0001802" ]

[]

null

false

true

2

GO:0001806

1,806

type IV hypersensitivity

biological_process

An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "delayed hypersensitivity response", "delayed-type hypersensitivity" ]

[ "EXACT", "EXACT" ]

[ "GO:0016069" ]

[]

[ "Wikipedia:Type_IV_hypersensitivity" ]

[ "GO:0002456", "GO:0002524" ]

[]

[ "GO:0002456", "GO:0002524" ]

[]

null

false

true

7

GO:0001807

1,807

regulation of type IV hypersensitivity

biological_process

Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[]

[ "GO:0002709", "GO:0002883" ]

[ "regulates GO:0001806" ]

[ "regulates" ]

[ "GO:0001806" ]

[ "GO:0001806", "GO:0002709", "GO:0002883" ]

[ "GO:0065007", "regulates GO:0001806" ]

[]

null

false

true

2

GO:0001808

1,808

negative regulation of type IV hypersensitivity

biological_process

Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "down regulation of type IV hypersensitivity", "down-regulation of type IV hypersensitivity", "downregulation of type IV hypersensitivity", "inhibition of type IV hypersensitivity" ]

[ "EXACT", "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0001807", "GO:0002710", "GO:0002884" ]

[ "negatively_regulates GO:0001806" ]

[ "negatively_regulates" ]

[ "GO:0001806" ]

[ "GO:0001806", "GO:0001807", "GO:0002710", "GO:0002884" ]

[ "GO:0065007", "negatively_regulates GO:0001806" ]

[]

null

false

true

1

GO:0001809

1,809

positive regulation of type IV hypersensitivity

biological_process

Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of type IV hypersensitivity", "stimulation of type IV hypersensitivity", "up regulation of type IV hypersensitivity", "up-regulation of type IV hypersensitivity", "upregulation of type IV hypersensitivity" ]

[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001807", "GO:0002711", "GO:0002885" ]

[ "positively_regulates GO:0001806" ]

[ "positively_regulates" ]

[ "GO:0001806" ]

[ "GO:0001806", "GO:0001807", "GO:0002711", "GO:0002885" ]

[ "GO:0065007", "positively_regulates GO:0001806" ]

[]

null

false

true

9

GO:0001810

1,810

regulation of type I hypersensitivity

biological_process

Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response.

[ "ISBN:0781735149" ]

null

[]

[ "GO:0002883", "GO:0002889" ]

[ "regulates GO:0016068" ]

[ "regulates" ]

[ "GO:0016068" ]

[ "GO:0002883", "GO:0002889", "GO:0016068" ]

[ "GO:0065007", "regulates GO:0016068" ]

[]

null

false

true

9

GO:0001812

1,812

positive regulation of type I hypersensitivity

biological_process

Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of type I hypersensitivity", "stimulation of type I hypersensitivity", "up regulation of type I hypersensitivity", "up-regulation of type I hypersensitivity", "upregulation of type I hypersensitivity" ]

[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001810", "GO:0002885", "GO:0002891" ]

[ "positively_regulates GO:0016068" ]

[ "positively_regulates" ]

[ "GO:0016068" ]

[ "GO:0001810", "GO:0002885", "GO:0002891", "GO:0016068" ]

[ "GO:0065007", "positively_regulates GO:0016068" ]

[]

null

false

true

9

GO:0001813

1,813

regulation of antibody-dependent cellular cytotoxicity

biological_process

Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "regulation of antibody dependent cell death", "regulation of antibody dependent cell killing", "regulation of antibody-dependent cell death", "regulation of antibody-dependent cell killing" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001796", "GO:0001910" ]

[ "regulates GO:0001788" ]

[ "regulates" ]

[ "GO:0001788" ]

[ "GO:0001788", "GO:0001796", "GO:0001910" ]

[ "GO:0065007", "regulates GO:0001788" ]

[]

null

false

true

6

GO:0001814

1,814

negative regulation of antibody-dependent cellular cytotoxicity

biological_process

Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "down regulation of antibody-dependent cellular cytotoxicity", "down-regulation of antibody-dependent cellular cytotoxicity", "downregulation of antibody-dependent cellular cytotoxicity", "inhibition of antibody-dependent cellular cytotoxicity", "negative regulation of antibody dependent cell death", "neg...

[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001797", "GO:0001813", "GO:0001911" ]

[ "negatively_regulates GO:0001788" ]

[ "negatively_regulates" ]

[ "GO:0001788" ]

[ "GO:0001788", "GO:0001797", "GO:0001813", "GO:0001911" ]

[ "GO:0065007", "negatively_regulates GO:0001788" ]

[]

null

false

true

4

GO:0001815

1,815

positive regulation of antibody-dependent cellular cytotoxicity

biological_process

Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "activation of antibody-dependent cellular cytotoxicity", "positive regulation of antibody dependent cell death", "positive regulation of antibody dependent cell killing", "positive regulation of antibody-dependent cell death", "positive regulation of antibody-dependent cell killing", "stimulation of anti...

[ "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0001798", "GO:0001813", "GO:0001912" ]

[ "positively_regulates GO:0001788" ]

[ "positively_regulates" ]

[ "GO:0001788" ]

[ "GO:0001788", "GO:0001798", "GO:0001813", "GO:0001912" ]

[ "GO:0065007", "positively_regulates GO:0001788" ]

[]

null

false

true

8

GO:0001817

1,817

regulation of cytokine production

biological_process

Any process that modulates the frequency, rate, or extent of production of a cytokine.

[ "GOC:add", "ISBN:0781735149" ]

null

[ "regulation of cytokine anabolism", "regulation of cytokine biosynthesis", "regulation of cytokine biosynthetic process", "regulation of cytokine formation", "regulation of cytokine secretion", "regulation of cytokine synthesis" ]

[ "EXACT", "EXACT", "NARROW", "EXACT", "NARROW", "EXACT" ]

[ "GO:0042035", "GO:0050707" ]

[]

[ "GO:0010468", "GO:0051239" ]

[ "regulates GO:0001816" ]

[ "regulates" ]

[ "GO:0001816" ]

[ "GO:0001816", "GO:0010468", "GO:0051239" ]

[ "GO:0065007", "regulates GO:0001816" ]

[]

null

false

true

3