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GO

Dataset card Data Studio Files
xet
 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0001934
1,934
positive regulation of protein phosphorylation
biological_process
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
[ "GOC:hjd" ]
null
[ "activation of protein amino acid phosphorylation", "positive regulation of protein amino acid phosphorylation", "stimulation of protein amino acid phosphorylation", "up regulation of protein amino acid phosphorylation", "up-regulation of protein amino acid phosphorylation", "upregulation of protein amino...
[ "NARROW", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[ "gocheck_obsoletion_candidate" ]
[]
[ "GO:0001932", "GO:0031401", "GO:0042327" ]
[ "positively_regulates GO:0006468" ]
[ "positively_regulates" ]
[ "GO:0006468" ]
[ "GO:0001932", "GO:0006468", "GO:0031401", "GO:0042327" ]
[ "GO:0065007", "positively_regulates GO:0006468" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27189\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28278\" xsd:anyURI" ]
null
null
false
true
2
GO:0001935
1,935
endothelial cell proliferation
biological_process
The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
[ "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0050673" ]
[]
[]
[]
[ "GO:0050673" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001937
1,937
negative regulation of endothelial cell proliferation
biological_process
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
[ "GOC:add" ]
null
[ "down regulation of endothelial cell proliferation", "down-regulation of endothelial cell proliferation", "downregulation of endothelial cell proliferation", "inhibition of endothelial cell proliferation" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0001936", "GO:0050680" ]
[ "negatively_regulates GO:0001935" ]
[ "negatively_regulates" ]
[ "GO:0001935" ]
[ "GO:0001935", "GO:0001936", "GO:0050680" ]
[ "GO:0065007", "negatively_regulates GO:0001935" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001938
1,938
positive regulation of endothelial cell proliferation
biological_process
Any process that activates or increases the rate or extent of endothelial cell proliferation.
[ "GOC:add" ]
null
[ "activation of endothelial cell proliferation", "stimulation of endothelial cell proliferation", "up regulation of endothelial cell proliferation", "up-regulation of endothelial cell proliferation", "upregulation of endothelial cell proliferation" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001936", "GO:0050679" ]
[ "positively_regulates GO:0001935" ]
[ "positively_regulates" ]
[ "GO:0001935" ]
[ "GO:0001935", "GO:0001936", "GO:0050679" ]
[ "GO:0065007", "positively_regulates GO:0001935" ]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001940
1,940
male pronucleus
cellular_component
The pronucleus originating from the spermatozoa that was involved in fertilization.
[ "GOC:hjd", "ISBN:0198506732" ]
null
[]
[]
[]
[]
[]
[ "GO:0045120" ]
[]
[]
[]
[ "GO:0045120" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001941
1,941
postsynaptic membrane organization
biological_process
A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
[ "GOC:dph", "GOC:pr" ]
null
[ "post-synaptic membrane organization", "postsynaptic membrane organisation" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0061024" ]
[ "part_of GO:0099173" ]
[ "part_of" ]
[ "GO:0099173" ]
[ "GO:0061024", "GO:0099173" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001942
1,942
hair follicle development
biological_process
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
[ "GOC:dph", "UBERON:0002073" ]
null
[]
[]
[ "GO:0001943" ]
[]
[]
[ "GO:0022405", "GO:0048856" ]
[ "part_of GO:0098773" ]
[ "part_of" ]
[ "GO:0098773" ]
[ "GO:0022405", "GO:0048856", "GO:0098773" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001944
1,944
vasculature development
biological_process
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
[ "GOC:dph", "UBERON:0002409" ]
null
[ "vascular system development" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0048731" ]
[ "part_of GO:0072359" ]
[ "part_of" ]
[ "GO:0072359" ]
[ "GO:0048731", "GO:0072359" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001945
1,945
lymph vessel development
biological_process
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
[ "GOC:dph", "UBERON:0001473" ]
null
[]
[]
[]
[]
[]
[ "GO:0048856" ]
[ "part_of GO:0001944" ]
[ "part_of" ]
[ "GO:0001944" ]
[ "GO:0001944", "GO:0048856" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001946
1,946
lymphangiogenesis
biological_process
Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.
[ "GOC:dph", "PMID:11596157" ]
null
[ "lymph vessel formation" ]
[ "EXACT" ]
[]
[]
[ "Wikipedia:Lymphangiogenesis" ]
[ "GO:0009653", "GO:0048646" ]
[ "part_of GO:0036303" ]
[ "part_of" ]
[ "GO:0036303" ]
[ "GO:0009653", "GO:0036303", "GO:0048646" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001947
1,947
heart looping
biological_process
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great a...
[ "GOC:dph", "PMID:12094232" ]
null
[ "cardiac looping" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0003143" ]
[ "part_of GO:0061371" ]
[ "part_of" ]
[ "GO:0061371" ]
[ "GO:0003143", "GO:0061371" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001949
1,949
sebaceous gland cell differentiation
biological_process
The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.
[ "GOC:mgi_curators", "PMID:15737203" ]
null
[ "sebocytes differentiation" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0009913" ]
[ "part_of GO:0048733" ]
[ "part_of" ]
[ "GO:0048733" ]
[ "GO:0009913", "GO:0048733" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001950
1,950
obsolete plasma membrane enriched fraction
cellular_component
OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes.
[ "GOC:mgi_curators", "PMID:11562363", "PMID:15601832" ]
This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.
[ "plasma membrane enriched fraction", "PME fraction" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005886" ]
[]
null
null
true
true
1
GO:0001951
1,951
intestinal D-glucose absorption
biological_process
Uptake of D-glucose into the blood by absorption from the small intestine.
[ "GOC:mgi_curators", "PMID:5601832" ]
null
[]
[]
[]
[]
[]
[ "GO:0106001" ]
[]
[]
[]
[ "GO:0106001" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001953
1,953
negative regulation of cell-matrix adhesion
biological_process
Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.
[ "GOC:hjd" ]
null
[ "down regulation of cell-matrix adhesion", "down-regulation of cell-matrix adhesion", "downregulation of cell-matrix adhesion", "inhibition of cell-matrix adhesion" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0001952", "GO:0010812" ]
[ "negatively_regulates GO:0007160" ]
[ "negatively_regulates" ]
[ "GO:0007160" ]
[ "GO:0001952", "GO:0007160", "GO:0010812" ]
[ "GO:0065007", "negatively_regulates GO:0007160" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001954
1,954
positive regulation of cell-matrix adhesion
biological_process
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
[ "GOC:hjd" ]
null
[ "activation of cell-matrix adhesion", "stimulation of cell-matrix adhesion", "up regulation of cell-matrix adhesion", "up-regulation of cell-matrix adhesion", "upregulation of cell-matrix adhesion" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001952", "GO:0010811" ]
[ "positively_regulates GO:0007160" ]
[ "positively_regulates" ]
[ "GO:0007160" ]
[ "GO:0001952", "GO:0007160", "GO:0010811" ]
[ "GO:0065007", "positively_regulates GO:0007160" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001955
1,955
blood vessel maturation
biological_process
A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.
[ "GOC:dph" ]
null
[]
[]
[]
[]
[]
[ "GO:0071695" ]
[ "part_of GO:0001568" ]
[ "part_of" ]
[ "GO:0001568" ]
[ "GO:0001568", "GO:0071695" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001956
1,956
positive regulation of neurotransmitter secretion
biological_process
Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.
[ "GOC:hjd" ]
null
[ "activation of neurotransmitter secretion", "stimulation of neurotransmitter secretion", "up regulation of neurotransmitter secretion", "up-regulation of neurotransmitter secretion", "upregulation of neurotransmitter secretion" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046928", "GO:0050806", "GO:0051590", "GO:1903532" ]
[ "positively_regulates GO:0007269" ]
[ "positively_regulates" ]
[ "GO:0007269" ]
[ "GO:0007269", "GO:0046928", "GO:0050806", "GO:0051590", "GO:1903532" ]
[ "GO:0065007", "positively_regulates GO:0007269" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001957
1,957
intramembranous ossification
biological_process
Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.
[ "ISBN:0878932437" ]
An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.
[ "dermal ossification", "intramembranous bone ossification" ]
[ "NARROW", "RELATED" ]
[]
[]
[ "Wikipedia:Intramembranous_ossification" ]
[ "GO:0036072" ]
[]
[]
[]
[ "GO:0036072" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001959
1,959
regulation of cytokine-mediated signaling pathway
biological_process
Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.
[ "GOC:hjd" ]
null
[ "regulation of cytokine and chemokine mediated signaling pathway", "regulation of cytokine mediated signaling pathway", "regulation of cytokine mediated signalling pathway" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-8939247 \"RUNX1 regulates transcription of genes involved in interleukin signaling\"" ]
[ "GO:0009966", "GO:0060759" ]
[ "regulates GO:0019221" ]
[ "regulates" ]
[ "GO:0019221" ]
[ "GO:0009966", "GO:0019221", "GO:0060759" ]
[ "GO:0065007", "regulates GO:0019221" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001960
1,960
negative regulation of cytokine-mediated signaling pathway
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.
[ "GOC:hjd" ]
null
[ "down regulation of cytokine mediated signaling pathway", "down-regulation of cytokine mediated signaling pathway", "downregulation of cytokine mediated signaling pathway", "inhibition of cytokine mediated signaling pathway", "negative regulation of cytokine and chemokine mediated signaling pathway", "neg...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001959", "GO:0009968", "GO:0060761" ]
[ "negatively_regulates GO:0019221" ]
[ "negatively_regulates" ]
[ "GO:0019221" ]
[ "GO:0001959", "GO:0009968", "GO:0019221", "GO:0060761" ]
[ "GO:0065007", "negatively_regulates GO:0019221" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001961
1,961
positive regulation of cytokine-mediated signaling pathway
biological_process
Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
[ "GOC:hjd" ]
null
[ "activation of cytokine mediated signaling pathway", "positive regulation of cytokine and chemokine mediated signaling pathway", "positive regulation of cytokine mediated signaling pathway", "positive regulation of cytokine mediated signalling pathway", "stimulation of cytokine mediated signaling pathway", ...
[ "NARROW", "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001959", "GO:0009967", "GO:0060760" ]
[ "positively_regulates GO:0019221" ]
[ "positively_regulates" ]
[ "GO:0019221" ]
[ "GO:0001959", "GO:0009967", "GO:0019221", "GO:0060760" ]
[ "GO:0065007", "positively_regulates GO:0019221" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001962
1,962
alpha-1,3-galactosyltransferase activity
molecular_function
Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.
[ "GOC:hjd", "PMID:10854427" ]
null
[ "isoglobotriaosylceramide synthase" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0008378" ]
[]
[]
[]
[ "GO:0008378" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001963
1,963
synaptic transmission, dopaminergic
biological_process
The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cyt...
[ "GOC:dos", "GOC:dph" ]
null
[ "dopaminergic synaptic transmission" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007268" ]
[]
[]
[]
[ "GO:0007268" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001965
1,965
G-protein alpha-subunit binding
molecular_function
Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
[ "GOC:hjd" ]
null
[ "G-alpha protein subunit binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001966
1,966
thigmotaxis
biological_process
The directed movement of an organism along a spatial gradient of mechanical contact with solid surfaces, typically manifested as a preference for maintaining proximity to walls, edges, or boundaries.
[ "PMID:22197677", "PMID:35992075", "PMID:7913324" ]
In behavioral neuroscience, thigmotaxis commonly refers to the tendency of animals to remain close to walls or edges when placed in an open arena, often used as an index of anxiety-related behavior. This is observed across taxa including rodents, fish, insects, and nematodes. The behavior is mediated by mechanosensory ...
[ "taxis in response to mechanical stimulus", "taxis in response to touch stimulus", "thigmotactic behavior", "wall-following behavior" ]
[ "BROAD", "EXACT", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0007610" ]
[]
[]
[]
[ "GO:0007610" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31328\" xsd:anyURI" ]
null
null
false
true
3
GO:0001967
1,967
suckling behavior
biological_process
Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
[ "GOC:dph", "GOC:pr" ]
null
[ "nursing behavior" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007631" ]
[]
[]
[]
[ "GO:0007631" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001970
1,970
positive regulation of activation of membrane attack complex
biological_process
Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
[ "GOC:hjd" ]
null
[ "activation of activation of membrane attack complex", "positive regulation of activation of MAC", "positive regulation of activation of TCC", "positive regulation of activation of terminal complement complex", "positive regulation of activation of the terminal complement cascade", "positive regulation of...
[ "NARROW", "EXACT", "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001969", "GO:0045917" ]
[ "positively_regulates GO:0001905" ]
[ "positively_regulates" ]
[ "GO:0001905" ]
[ "GO:0001905", "GO:0001969", "GO:0045917" ]
[ "GO:0065007", "positively_regulates GO:0001905" ]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001971
1,971
negative regulation of activation of membrane attack complex
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
[ "GOC:hjd" ]
null
[ "down regulation of activation of membrane attack complex", "down-regulation of activation of membrane attack complex", "downregulation of activation of membrane attack complex", "inhibition of activation of membrane attack complex", "negative regulation of activation of MAC", "negative regulation of acti...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001969", "GO:0045916" ]
[ "negatively_regulates GO:0001905" ]
[ "negatively_regulates" ]
[ "GO:0001905" ]
[ "GO:0001905", "GO:0001969", "GO:0045916" ]
[ "GO:0065007", "negatively_regulates GO:0001905" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001972
1,972
retinoic acid binding
molecular_function
Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0005501", "GO:0033293" ]
[]
[]
[]
[ "GO:0005501", "GO:0033293" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001973
1,973
G protein-coupled adenosine receptor signaling pathway
biological_process
The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
[ "GOC:dph" ]
null
[ "adenosine receptor signaling pathway", "adenosine receptor signaling pathway, G-protein coupled", "adenosine receptor signalling pathway", "P1 receptor signaling pathway" ]
[ "RELATED", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0035588" ]
[]
[]
[]
[ "GO:0035588" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001974
1,974
blood vessel remodeling
biological_process
The reorganization or renovation of existing blood vessels.
[ "GOC:hjd" ]
null
[ "blood vessel remodelling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0048771" ]
[]
[]
[]
[ "GO:0048771" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001975
1,975
response to amphetamine
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
[ "GOC:dph", "GOC:ef" ]
null
[]
[]
[]
[]
[]
[ "GO:0014075" ]
[]
[]
[]
[ "GO:0014075" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0001976
1,976
nervous system process involved in regulation of systemic arterial blood pressure
biological_process
The regulation of blood pressure mediated by detection of stimuli and a neurological response.
[ "GOC:mtg_cardio", "ISBN:0721643949" ]
null
[ "blood pressure regulation by neurological process", "fast control of arterial pressure", "neurological process involved in regulation of systemic arterial blood pressure", "neurological system process involved in regulation of systemic arterial blood pressure" ]
[ "EXACT", "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0050877" ]
[ "part_of GO:0003073" ]
[ "part_of" ]
[ "GO:0003073" ]
[ "GO:0003073", "GO:0050877" ]
[ "GO:0050877", "part_of GO:0003073" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001977
1,977
obsolete renal system process involved in regulation of blood volume
biological_process
OBSOLETE. A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.
[ "GOC:dph", "GOC:tb", "ISBN:0721643949" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "renal blood volume control of blood pressure", "renal regulation of blood volume" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
null
null
true
true
2
GO:0001978
1,978
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback
biological_process
The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.
[ "GOC:dph", "GOC:tb", "ISBN:0721643949" ]
null
[ "baroreceptor feedback control of blood pressure", "baroreceptor pressure buffer system", "carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure" ]
[ "RELATED", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0001976" ]
[ "part_of GO:0003025" ]
[ "part_of" ]
[ "GO:0003025" ]
[ "GO:0001976", "GO:0003025" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001979
1,979
regulation of systemic arterial blood pressure by chemoreceptor signaling
biological_process
The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
[ "GOC:dph", "GOC:tb", "ISBN:0721643949" ]
null
[ "chemoreceptor control of blood pressure", "chemoreceptor regulation of systemic arterial blood pressure", "regulation of systemic arterial blood pressure by chemoreceptor signalling" ]
[ "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001976" ]
[]
[]
[]
[ "GO:0001976" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001981
1,981
baroreceptor detection of arterial stretch
biological_process
The series of events by which the change in diameter of an artery is detected and converted to a molecular signal.
[ "GOC:mtg_cardio", "ISBN:0721643949" ]
null
[]
[]
[]
[]
[]
[ "GO:0003018", "GO:0050982" ]
[ "part_of GO:0001978" ]
[ "part_of" ]
[ "GO:0001978" ]
[ "GO:0001978", "GO:0003018", "GO:0050982" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001982
1,982
baroreceptor response to decreased systemic arterial blood pressure
biological_process
The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels.
[ "GOC:dph", "GOC:mtg_cardio", "ISBN:0323031951", "ISBN:0721643949" ]
null
[]
[]
[]
[]
[]
[ "GO:0001978", "GO:0003084" ]
[]
[]
[]
[ "GO:0001978", "GO:0003084" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001983
1,983
baroreceptor response to increased systemic arterial blood pressure
biological_process
The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels.
[ "GOC:mtg_cardio", "ISBN:0323031951", "ISBN:0721643949" ]
null
[]
[]
[]
[]
[]
[ "GO:0001978", "GO:0003085" ]
[]
[]
[]
[ "GO:0001978", "GO:0003085" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001984
1,984
artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
biological_process
An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.
[ "ISBN:0721643949" ]
null
[ "vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0042311" ]
[ "part_of GO:0001983" ]
[ "part_of" ]
[ "GO:0001983" ]
[ "GO:0001983", "GO:0042311" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001985
1,985
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.
[ "ISBN:0721643949" ]
null
[ "down regulation of heart contraction rate in baroreceptor response to increased blood pressure", "down-regulation of heart contraction rate in baroreceptor response to increased blood pressure", "downregulation of heart contraction rate in baroreceptor response to increased blood pressure", "inhibition of he...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0010459" ]
[ "part_of GO:0001983" ]
[ "part_of" ]
[ "GO:0001983" ]
[ "GO:0001983", "GO:0010459" ]
[ "GO:0010459", "part_of GO:0001983" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0001986
1,986
negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure
biological_process
Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.
[ "GOC:mtg_cardio", "ISBN:0721643949" ]
null
[ "decreased force of heart contraction during baroreceptor response to increased systemic arterial blood pressure", "decreased strength of cardiac contraction during baroreceptor response to increased blood pressure" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0045822" ]
[ "part_of GO:0001983" ]
[ "part_of" ]
[ "GO:0001983" ]
[ "GO:0001983", "GO:0045822" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0001987
1,987
vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure
biological_process
A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure.
[ "ISBN:0721643949" ]
null
[]
[]
[]
[]
[]
[ "GO:0042310" ]
[ "part_of GO:0001982" ]
[ "part_of" ]
[ "GO:0001982" ]
[ "GO:0001982", "GO:0042310" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0001988
1,988
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
biological_process
Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.
[ "ISBN:0721643949" ]
null
[ "activation of heart contraction rate in baroreceptor response to decreased blood pressure", "positive control of heart contraction rate in baroreceptor response to decreased blood pressure", "positive regulation of cardiac contraction rate in baroreceptor response to decreased blood pressure", "positive regu...
[ "NARROW", "EXACT", "EXACT", "RELATED", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010460" ]
[ "part_of GO:0001982" ]
[ "part_of" ]
[ "GO:0001982" ]
[ "GO:0001982", "GO:0010460" ]
[ "GO:0010460", "part_of GO:0001982" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0001989
1,989
obsolete positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure
biological_process
OBSOLETE. Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure.
[ "ISBN:0721643949" ]
This term was obsoleted because it represents a GO-CAM model.
[ "increased force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure", "increased strength of cardiac contraction during baroreceptor response to decreased blood pressure", "positive regulation of the force of heart contraction during baroreceptor response to decrease...
[ "RELATED", "RELATED", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25766\" xsd:anyURI" ]
null
null
true
true
2
GO:0001990
1,990
regulation of systemic arterial blood pressure by hormone
biological_process
The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, ...
[ "GOC:mtg_cardio", "ISBN:0721643949" ]
null
[ "blood pressure regulation by hormone", "hormonal control of blood pressure", "hormonal regulation of blood pressure" ]
[ "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0003044", "GO:0050886" ]
[]
[]
[]
[ "GO:0003044", "GO:0050886" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0001991
1,991
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
biological_process
The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.
[ "ISBN:0721643949" ]
null
[ "circulatory renin-angiotensin blood pressure regulation", "circulatory renin-angiotensin control of blood pressure", "circulatory renin-angiotensin regulation of blood pressure", "control of blood pressure by circulatory renin-angiotensin", "renin-angiotensin blood pressure control" ]
[ "EXACT", "RELATED", "EXACT", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0003081" ]
[]
[]
[]
[ "GO:0003081" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001992
1,992
regulation of systemic arterial blood pressure by vasopressin
biological_process
The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.
[ "GOC:mtg_cardio", "ISBN:0721643949" ]
null
[ "blood pressure regulation by vasopressin", "vasopressin control of blood pressure" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0001990" ]
[]
[]
[]
[ "GO:0001990" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0001993
1,993
regulation of systemic arterial blood pressure by norepinephrine-epinephrine
biological_process
The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system.
[ "ISBN:0721643949" ]
null
[ "noradrenaline-adrenaline regulation of blood pressure", "norepinephrine-epinephrine blood pressure control", "norepinephrine-epinephrine blood pressure regulation" ]
[ "RELATED", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0003044" ]
[]
[]
[]
[ "GO:0003044" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001994
1,994
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
biological_process
A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure.
[ "GOC:mtg_cardio", "ISBN:0721643949" ]
null
[ "noradrenaline-adrenaline vasoconstriction involved in regulation of blood pressure", "norepinephrine-epinephrine vasoconstriction during blood pressure control", "norepinephrine-epinephrine vasoconstriction during blood pressure regulation", "norepinephrine-epinephrine vasoconstriction during control of bloo...
[ "EXACT", "RELATED", "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0042310" ]
[ "part_of GO:0003321" ]
[ "part_of" ]
[ "GO:0003321" ]
[ "GO:0003321", "GO:0042310" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001995
1,995
norepinephrine-epinephrine catabolic process in blood stream
biological_process
The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.
[ "GOC:hjd" ]
null
[ "noradrenaline-adrenalin catabolic process in blood stream" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0042419" ]
[ "part_of GO:0001993" ]
[ "part_of" ]
[ "GO:0001993" ]
[ "GO:0001993", "GO:0042419" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001996
1,996
positive regulation of heart rate by epinephrine-norepinephrine
biological_process
The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction.
[ "GOC:dph" ]
null
[ "activation of heart contraction rate by epinephrine-norepinephrine", "increased chronotropy by epinephrine-norepinephrine", "positive control of heart contraction rate by epinephrine-norepinephrine", "positive regulation of cardiac contraction rate by epinephrine-norepinephrine", "positive regulation of he...
[ "NARROW", "RELATED", "RELATED", "EXACT", "EXACT", "RELATED", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010460" ]
[ "part_of GO:0003321" ]
[ "part_of" ]
[ "GO:0003321" ]
[ "GO:0003321", "GO:0010460" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0001998
1,998
angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
biological_process
The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.
[ "GOC:mtg_cardio", "GOC:pr", "ISBN:0721643949" ]
null
[ "angiotensin mediated vasoconstriction during blood pressure control", "angiotensin mediated vasoconstriction during blood pressure regulation", "angiotensin mediated vasoconstriction during control of blood pressure", "angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pr...
[ "RELATED", "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0003084", "GO:0042310" ]
[ "part_of GO:0002034" ]
[ "part_of" ]
[ "GO:0002034" ]
[ "GO:0002034", "GO:0003084", "GO:0042310" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0001999
1,999
renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
biological_process
The physiological response of the kidneys to a decrease in blood flow.
[ "GOC:dph" ]
null
[ "renal response to blood flow during renin-angiotensin control of blood pressure" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0003071" ]
[ "part_of GO:0001991" ]
[ "part_of" ]
[ "GO:0001991" ]
[ "GO:0001991", "GO:0003071" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002000
2,000
detection of renal blood flow
biological_process
The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal.
[ "ISBN:0721643949" ]
null
[]
[]
[]
[]
[]
[ "GO:0050982" ]
[ "part_of GO:0001999" ]
[ "part_of" ]
[ "GO:0001999" ]
[ "GO:0001999", "GO:0050982" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002001
2,001
renin secretion into blood stream
biological_process
The regulated release of renin into the blood stream by juxtoglomerular cells.
[ "ISBN:0721643949" ]
null
[ "renin release into blood stream" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0009306", "GO:0023061" ]
[ "part_of GO:0001999" ]
[ "part_of" ]
[ "GO:0001999" ]
[ "GO:0001999", "GO:0009306", "GO:0023061" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002002
2,002
regulation of angiotensin levels in blood
biological_process
The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal...
[ "GOC:rl", "PMID:21951628", "Wikipedia:Angiotensin" ]
null
[ "control of angiotensin levels in blood", "control of blood angiotensin level", "regulation of blood angiotensin level" ]
[ "RELATED", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0010817" ]
[ "part_of GO:0001991" ]
[ "part_of" ]
[ "GO:0001991" ]
[ "GO:0001991", "GO:0010817" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15424\" xsd:anyURI" ]
null
null
false
true
4
GO:0002003
2,003
angiotensin maturation
biological_process
The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood.
[ "ISBN:0721643949" ]
null
[ "angiotensin catabolic process in blood" ]
[ "NARROW" ]
[ "GO:0002005" ]
[]
[ "Reactome:R-HSA-2022377 \"Metabolism of Angiotensinogen to Angiotensins\"" ]
[ "GO:0016486" ]
[ "part_of GO:0002002" ]
[ "part_of" ]
[ "GO:0002002" ]
[ "GO:0002002", "GO:0016486" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002006
2,006
obsolete vasoconstriction by vasopressin involved in systemic arterial blood pressure control
biological_process
OBSOLETE. The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream.
[ "GOC:dph", "GOC:mtg_cardio", "GOC:tb", "ISBN:0721643949" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0003084" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
1
GO:0002007
2,007
detection of hypoxic conditions in blood by chemoreceptor signaling
biological_process
The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
[ "GOC:dph" ]
null
[ "detection of hypoxic conditions in blood by chemoreceptor signalling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0009593" ]
[ "has_part GO:0003022", "part_of GO:0001979", "part_of GO:0070887" ]
[ "has_part", "part_of", "part_of" ]
[ "GO:0003022", "GO:0001979", "GO:0070887" ]
[ "GO:0001979", "GO:0003022", "GO:0009593", "GO:0070887" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002008
2,008
excitation of vasomotor center by chemoreceptor signaling
biological_process
The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
[ "GOC:dph" ]
null
[ "excitation of vasomotor center by chemoreceptor signalling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001976" ]
[ "part_of GO:0001979", "part_of GO:0003084" ]
[ "part_of", "part_of" ]
[ "GO:0001979", "GO:0003084" ]
[ "GO:0001976", "GO:0001979", "GO:0003084" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002009
2,009
morphogenesis of an epithelium
biological_process
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
[ "GOC:dph", "GOC:jl", "GOC:tb", "ISBN:0198506732" ]
null
[ "epithelium morphogenesis" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0048729" ]
[ "part_of GO:0060429" ]
[ "part_of" ]
[ "GO:0060429" ]
[ "GO:0048729", "GO:0060429" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002010
2,010
excitation of vasomotor center by baroreceptor signaling
biological_process
The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.
[ "GOC:dph" ]
null
[ "excitation of vasomotor center by baroreceptor signalling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001976" ]
[ "part_of GO:0001982" ]
[ "part_of" ]
[ "GO:0001982" ]
[ "GO:0001976", "GO:0001982" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002012
2,012
obsolete vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure
biological_process
OBSOLETE. A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
[ "GOC:dph", "GOC:mtg_cardio" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
null
null
true
true
9
GO:0002013
2,013
detection of carbon dioxide by vasomotor center
biological_process
The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.
[ "ISBN:0721643949" ]
null
[]
[]
[]
[]
[]
[ "GO:0003031" ]
[ "part_of GO:0001980" ]
[ "part_of" ]
[ "GO:0001980" ]
[ "GO:0001980", "GO:0003031" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002014
2,014
vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
biological_process
The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system.
[ "GOC:mtg_cardio", "ISBN:0721643949" ]
null
[]
[]
[]
[]
[]
[ "GO:0003084", "GO:0042310" ]
[ "part_of GO:0001980" ]
[ "part_of" ]
[ "GO:0001980" ]
[ "GO:0001980", "GO:0003084", "GO:0042310" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002015
2,015
regulation of systemic arterial blood pressure by atrial baroreceptor feedback
biological_process
A process that controls blood pressure by sensing the amount of stretch occurring in the atria.
[ "GOC:dph", "GOC:tb" ]
null
[ "atrial baroreceptor regulation of systemic arterial blood pressure", "atrial control of blood pressure", "atrial low pressure baroreceptor regulation of blood pressure", "atrial reflex" ]
[ "EXACT", "RELATED", "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0003015" ]
[ "part_of GO:0003025" ]
[ "part_of" ]
[ "GO:0003025" ]
[ "GO:0003015", "GO:0003025" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002016
2,016
regulation of blood volume by renin-angiotensin
biological_process
The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.
[ "GOC:dph", "GOC:mtg_cardio", "GOC:tb", "ISBN:0721643949" ]
null
[ "renin-angiotensin control of body fluid levels", "renin-angiotensin regulation of blood volume" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0003081" ]
[]
[]
[]
[ "GO:0003081" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002017
2,017
regulation of blood volume by renal aldosterone
biological_process
The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.
[ "GOC:dph", "GOC:tb", "ISBN:0721643949" ]
null
[ "aldosterone mediated control of body fluids", "aldosterone mediated regulation of blood volume", "renal regulation of blood volume by aldosterone" ]
[ "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001990", "GO:0003084" ]
[]
[]
[]
[ "GO:0001990", "GO:0003084" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002018
2,018
renin-angiotensin regulation of aldosterone production
biological_process
The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.
[ "ISBN:0721643949" ]
null
[ "renin-angiotensin control of aldosterone production" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0003071", "GO:2000858" ]
[ "part_of GO:0002016" ]
[ "part_of" ]
[ "GO:0002016" ]
[ "GO:0002016", "GO:0003071", "GO:2000858" ]
[ "GO:0003014", "part_of GO:0002016", "regulates GO:0035932" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002019
2,019
regulation of renal output by angiotensin
biological_process
The process in which angiotensin directly modulates the rate of urine output by the kidney.
[ "GOC:dph", "GOC:mtg_cardio", "GOC:tb", "ISBN:0721643949" ]
null
[ "angiotensin mediated control of renal output", "angiotensin mediated regulation of renal output", "angiotensin-mediated regulation of renal output" ]
[ "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002016" ]
[]
[]
[]
[ "GO:0002016" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002020
2,020
protease binding
molecular_function
Binding to a protease or a peptidase.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-1297354 \"Acrosin Cleavage\"" ]
[ "GO:0019899" ]
[]
[]
[]
[ "GO:0019899" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002022
2,022
detection of dietary excess
biological_process
The neurological process in which the brain senses excessive caloric intake.
[ "PMID:12161655" ]
null
[]
[]
[]
[]
[]
[ "GO:0050877" ]
[ "part_of GO:0002021" ]
[ "part_of" ]
[ "GO:0002021" ]
[ "GO:0002021", "GO:0050877" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002023
2,023
reduction of food intake in response to dietary excess
biological_process
An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients.
[ "GOC:pg", "GOC:pr", "PMID:12161655", "PMID:12840200" ]
null
[]
[]
[]
[]
[]
[ "GO:0042755" ]
[ "part_of GO:0002021" ]
[ "part_of" ]
[ "GO:0002021" ]
[ "GO:0002021", "GO:0042755" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002024
2,024
diet induced thermogenesis
biological_process
The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signaling in the sympathetic nervous system.
[ "PMID:12161655" ]
null
[]
[]
[]
[]
[]
[ "GO:1990845" ]
[ "part_of GO:0002021" ]
[ "part_of" ]
[ "GO:0002021" ]
[ "GO:0002021", "GO:1990845" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002025
2,025
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
biological_process
A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.
[ "GOC:mtg_cardio", "PMID:10358008" ]
null
[ "noradrenaline-adrenaline vasodilation involved in regulation of blood pressure", "norepinephrine-epinephrine vasodilation during blood pressure regulation", "vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0003085", "GO:0042311" ]
[ "part_of GO:0001993" ]
[ "part_of" ]
[ "GO:0001993" ]
[ "GO:0001993", "GO:0003085", "GO:0042311" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002026
2,026
regulation of the force of heart contraction
biological_process
Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
[ "GOC:dph", "GOC:tb", "PMID:10358008" ]
null
[ "cardiac inotropy", "heart inotropy" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008016", "GO:0065008" ]
[]
[]
[]
[ "GO:0008016", "GO:0065008" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002027
2,027
regulation of heart rate
biological_process
Any process that modulates the frequency or rate of heart contraction.
[ "GOC:dph", "GOC:tb", "PMID:10358008" ]
null
[ "cardiac chronotropy", "regulation of heart contraction rate", "regulation of rate of heart contraction" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008016", "GO:0065008" ]
[]
[]
[]
[ "GO:0008016", "GO:0065008" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002028
2,028
regulation of sodium ion transport
biological_process
Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
[ "GOC:dph" ]
null
[ "regulation of Na+ transport", "regulation of sodium transport" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010959" ]
[ "regulates GO:0006814" ]
[ "regulates" ]
[ "GO:0006814" ]
[ "GO:0006814", "GO:0010959" ]
[ "GO:0065007", "regulates GO:0006814" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002029
2,029
desensitization of G protein-coupled receptor signaling pathway
biological_process
The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway.
[ "PMID:8396717" ]
null
[ "desensitisation of G-protein coupled receptor protein signalling pathway", "desensitization of G-protein coupled receptor protein signaling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0022401", "GO:0045744" ]
[]
[]
[]
[ "GO:0022401", "GO:0045744" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002030
2,030
inhibitory G protein-coupled receptor phosphorylation
biological_process
The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site.
[ "PMID:8396717" ]
null
[ "inhibitory G-protein coupled receptor phosphorylation" ]
[ "EXACT" ]
[]
[ "gocheck_obsoletion_candidate" ]
[]
[ "GO:0006468" ]
[ "part_of GO:0002029" ]
[ "part_of" ]
[ "GO:0002029" ]
[ "GO:0002029", "GO:0006468" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002032
2,032
obsolete desensitization of G protein-coupled receptor signaling pathway by arrestin
biological_process
OBSOLETE. The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.
[ "GOC:dph", "GOC:tb", "PMID:8396717" ]
The reason for obsoletion is that this term represents a gene product arrestin.
[ "arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway", "arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway", "arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway", "desensitization of G-protein ...
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0002029" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27983\" xsd:anyURI" ]
null
null
true
true
7
GO:0002033
2,033
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure
biological_process
The process that increases the diameter of a blood vessel via the renin-angiotensin system.
[ "GOC:pr", "ISBN:0323031951", "PMID:10425188" ]
null
[ "vasodilation by angiotensin involved in regulation of systemic arterial blood pressure" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0003085", "GO:0042311" ]
[ "part_of GO:0002034" ]
[ "part_of" ]
[ "GO:0002034" ]
[ "GO:0002034", "GO:0003085", "GO:0042311" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002034
2,034
maintenance of blood vessel diameter homeostasis by renin-angiotensin
biological_process
The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.
[ "GOC:dph", "GOC:pr", "GOC:tb" ]
null
[ "regulation of blood vessel diameter by renin-angiotensin", "regulation of blood vessel size by renin-angiotensin", "renin-angiotensin regulation of blood vessel size" ]
[ "EXACT", "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0003081", "GO:0097746" ]
[]
[]
[]
[ "GO:0003081", "GO:0097746" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12253\" xsd:anyURI" ]
null
null
false
true
2
GO:0002035
2,035
brain renin-angiotensin system
biological_process
The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.
[ "PMID:2909574" ]
null
[]
[]
[]
[]
[]
[ "GO:0001976", "GO:0002016" ]
[]
[]
[]
[ "GO:0001976", "GO:0002016" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002037
2,037
negative regulation of L-glutamate import across plasma membrane
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.
[ "GOC:TermGenie" ]
null
[ "down regulation of L-glutamate import", "down regulation of L-glutamate transport", "down regulation of L-glutamate uptake", "down-regulation of L-glutamate import", "down-regulation of L-glutamate transport", "down-regulation of L-glutamate uptake", "downregulation of L-glutamate import", "downregul...
[ "EXACT", "BROAD", "RELATED", "EXACT", "BROAD", "RELATED", "EXACT", "BROAD", "RELATED", "NARROW", "NARROW", "NARROW", "BROAD", "BROAD", "RELATED", "BROAD" ]
[ "GO:1900921" ]
[]
[]
[ "GO:0002036", "GO:0032891", "GO:0034763", "GO:0051956" ]
[ "negatively_regulates GO:0098712" ]
[ "negatively_regulates" ]
[ "GO:0098712" ]
[ "GO:0002036", "GO:0032891", "GO:0034763", "GO:0051956", "GO:0098712" ]
[ "GO:0065007", "negatively_regulates GO:0098712" ]
[]
[]
[]
[]
[]
al
2012-06-13T07:34:30Z
false
true
4
GO:0002038
2,038
positive regulation of L-glutamate import across plasma membrane
biological_process
Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.
[ "GOC:TermGenie" ]
null
[ "activation of L-glutamate import", "activation of L-glutamate transport", "activation of L-glutamate uptake", "positive regulation of L-glutamate import", "positive regulation of L-glutamate transport", "positive regulation of L-glutamate uptake", "stimulation of L-glutamate transport", "up regulatio...
[ "NARROW", "NARROW", "NARROW", "BROAD", "BROAD", "RELATED", "NARROW", "EXACT", "BROAD", "RELATED", "EXACT", "EXACT", "RELATED", "EXACT", "BROAD", "RELATED" ]
[ "GO:1900922" ]
[]
[]
[ "GO:0002036", "GO:0032892", "GO:0034764", "GO:0051957" ]
[ "positively_regulates GO:0098712" ]
[ "positively_regulates" ]
[ "GO:0098712" ]
[ "GO:0002036", "GO:0032892", "GO:0034764", "GO:0051957", "GO:0098712" ]
[ "GO:0065007", "positively_regulates GO:0098712" ]
[]
[]
[]
[]
[]
al
2012-06-13T07:34:38Z
false
true
7
GO:0002039
2,039
p53 binding
molecular_function
Binding to one of the p53 family of proteins.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002040
2,040
sprouting angiogenesis
biological_process
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
[ "PMID:16391003", "PMID:23031691" ]
null
[]
[]
[]
[]
[]
[ "GO:0001525" ]
[]
[]
[]
[ "GO:0001525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002041
2,041
intussusceptive angiogenesis
biological_process
The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars.
[ "PMID:16391003" ]
null
[]
[]
[]
[]
[]
[ "GO:0001525" ]
[]
[]
[]
[ "GO:0001525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002042
2,042
cell migration involved in sprouting angiogenesis
biological_process
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
[ "PMID:16391003" ]
null
[]
[]
[]
[]
[]
[ "GO:0043534" ]
[ "part_of GO:0002040" ]
[ "part_of" ]
[ "GO:0002040" ]
[ "GO:0002040", "GO:0043534" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002043
2,043
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
biological_process
The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis.
[ "GOC:dph", "GOC:tb", "PMID:16391003" ]
null
[ "blood vessel endothelial cell proliferation during sprouting angiogenesis" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0001935" ]
[ "part_of GO:0002040" ]
[ "part_of" ]
[ "GO:0002040" ]
[ "GO:0001935", "GO:0002040" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002044
2,044
blood vessel endothelial cell migration involved in intussusceptive angiogenesis
biological_process
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.
[ "PMID:16391003" ]
null
[]
[]
[]
[]
[]
[ "GO:0043534" ]
[ "part_of GO:0002041" ]
[ "part_of" ]
[ "GO:0002041" ]
[ "GO:0002041", "GO:0043534" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002045
2,045
obsolete regulation of cell adhesion involved in intussusceptive angiogenesis
biological_process
OBSOLETE. The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis.
[ "PMID:16391003" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0002041", "GO:0030155" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
6
GO:0002046
2,046
opsin binding
molecular_function
Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
[ "GOC:hjd" ]
null
[ "metarhodopsin binding" ]
[ "NARROW" ]
[ "GO:0016030" ]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002047
2,047
phenazine biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.
[ "GOC:dph" ]
null
[ "acridizine biosynthesis", "acridizine biosynthetic process", "azophenylene biosynthesis", "azophenylene biosynthetic process", "dibenzo-p-diazine biosynthesis", "dibenzo-p-diazine biosynthetic process", "dibenzopyrazine biosynthesis", "dibenzopyrazine biosynthetic process" ]
[ "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0017000" ]
[]
[]
[]
[ "GO:0017000" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002049
2,049
pyoverdine biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
[ "PMID:15317763" ]
null
[]
[]
[]
[]
[]
[ "GO:0019290" ]
[]
[]
[]
[ "GO:0019290" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002052
2,052
positive regulation of neuroblast proliferation
biological_process
Any process that activates or increases the rate of neuroblast proliferation.
[ "GOC:dph" ]
null
[ "activation of neuroblast proliferation", "stimulation of neuroblast proliferation", "up regulation of neuroblast proliferation", "up-regulation of neuroblast proliferation", "upregulation of neuroblast proliferation" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0050769", "GO:1902692", "GO:2000179" ]
[ "positively_regulates GO:0007405" ]
[ "positively_regulates" ]
[ "GO:0007405" ]
[ "GO:0007405", "GO:0050769", "GO:1902692", "GO:2000179" ]
[ "GO:0065007", "positively_regulates GO:0007405" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002053
2,053
positive regulation of mesenchymal cell proliferation
biological_process
The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.
[ "GOC:dph" ]
null
[ "activation of mesenchymal cell proliferation", "stimulation of mesenchymal cell proliferation", "up regulation of mesenchymal cell proliferation", "up-regulation of mesenchymal cell proliferation", "upregulation of mesenchymal cell proliferation" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008284", "GO:0010464" ]
[ "positively_regulates GO:0010463" ]
[ "positively_regulates" ]
[ "GO:0010463" ]
[ "GO:0008284", "GO:0010463", "GO:0010464" ]
[ "GO:0065007", "positively_regulates GO:0010463" ]
[]
[]
[]
[]
[]
null
null
false
true
6