LiteFold/GO · Datasets at Hugging Face

GO:0002054

2,054

nucleobase binding

molecular_function

Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.

[ "GOC:hjd" ]

null

[]

[ "goslim_pir" ]

[]

[ "GO:1901363" ]

[]

[ "GO:1901363" ]

[]

null

false

true

7

GO:0002055

2,055

adenine binding

molecular_function

Binding to adenine, a purine base.

[ "GOC:hjd" ]

null

[ "6-aminopurine binding" ]

[ "EXACT" ]

[]

[ "GO:0002060" ]

[]

[ "GO:0002060" ]

[]

null

false

true

7

GO:0002056

2,056

cytosine binding

molecular_function

Binding to cytosine.

[ "GOC:hjd", "GOC:vw" ]

null

[]

[ "GO:0002061" ]

[]

[ "GO:0002061" ]

[]

null

false

true

6

GO:0002057

2,057

guanine binding

molecular_function

Binding to guanine.

[ "GOC:hjd" ]

null

[]

[ "GO:0002060" ]

[]

[ "GO:0002060" ]

[]

null

false

true

6

GO:0002058

2,058

uracil binding

molecular_function

Binding to uracil.

[ "GOC:hjd" ]

null

[]

[ "GO:0002061" ]

[]

[ "GO:0002061" ]

[]

null

false

true

6

GO:0002059

2,059

thymine binding

molecular_function

Binding to thymine.

[ "GOC:hjd" ]

null

[]

[ "GO:0002061" ]

[]

[ "GO:0002061" ]

[]

null

false

true

1

GO:0002060

2,060

purine nucleobase binding

molecular_function

Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.

[ "GOC:hjd" ]

null

[ "purine base binding", "purine binding" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0002054" ]

[]

[ "GO:0002054" ]

[]

null

false

true

6

GO:0002061

2,061

pyrimidine nucleobase binding

molecular_function

Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.

[ "GOC:hjd" ]

null

[ "1,3-diazine binding", "pyrimidine base binding", "pyrimidine binding" ]

[ "NARROW", "EXACT", "RELATED" ]

[]

[ "GO:0002054" ]

[]

[ "GO:0002054" ]

[]

null

false

true

3

GO:0002062

2,062

chondrocyte differentiation

biological_process

The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.

[ "GOC:dph" ]

null

[]

[ "GO:0030154" ]

[ "part_of GO:0051216" ]

[ "part_of" ]

[ "GO:0051216" ]

[ "GO:0030154", "GO:0051216" ]

[]

null

false

true

9

GO:0002064

2,064

epithelial cell development

biological_process

The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.

[ "GOC:dph" ]

null

[]

[ "GO:0048468" ]

[ "part_of GO:0030855" ]

[ "part_of" ]

[ "GO:0030855" ]

[ "GO:0030855", "GO:0048468" ]

[]

null

false

true

6

GO:0002065

2,065

columnar/cuboidal epithelial cell differentiation

biological_process

The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.

[ "GOC:dph" ]

null

[]

[ "GO:0030855" ]

[]

[ "GO:0030855" ]

[]

null

false

true

6

GO:0002066

2,066

columnar/cuboidal epithelial cell development

biological_process

The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column...

[ "GOC:dph" ]

null

[]

[ "GO:0002064" ]

[ "part_of GO:0002065" ]

[ "part_of" ]

[ "GO:0002065" ]

[ "GO:0002064", "GO:0002065" ]

[]

null

false

true

1

GO:0002067

2,067

glandular epithelial cell differentiation

biological_process

The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.

[ "GOC:dph" ]

null

[]

[ "GO:0002065" ]

[]

[ "GO:0002065" ]

[]

null

false

true

4

GO:0002068

2,068

glandular epithelial cell development

biological_process

The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.

[ "GOC:dph" ]

null

[]

[ "GO:0002066" ]

[ "part_of GO:0002067" ]

[ "part_of" ]

[ "GO:0002067" ]

[ "GO:0002066", "GO:0002067" ]

[]

null

false

true

6

GO:0002069

2,069

columnar/cuboidal epithelial cell maturation

biological_process

The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the...

[ "GOC:dph" ]

null

[]

[ "GO:0002070" ]

[ "part_of GO:0002066" ]

[ "part_of" ]

[ "GO:0002066" ]

[ "GO:0002066", "GO:0002070" ]

[]

null

false

true

1

GO:0002070

2,070

epithelial cell maturation

biological_process

The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.

[ "GOC:dph" ]

null

[]

[ "GO:0048469" ]

[ "part_of GO:0002064" ]

[ "part_of" ]

[ "GO:0002064" ]

[ "GO:0002064", "GO:0048469" ]

[]

null

false

true

9

GO:0002071

2,071

glandular epithelial cell maturation

biological_process

The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland...

[ "GOC:dph" ]

null

[]

[ "GO:0002069" ]

[ "part_of GO:0002068" ]

[ "part_of" ]

[ "GO:0002068" ]

[ "GO:0002068", "GO:0002069" ]

[]

null

false

true

4

GO:0002072

2,072

optic cup morphogenesis involved in camera-type eye development

biological_process

The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the ...

[ "GOC:dph", "GOC:mtg_sensu", "GOC:sdb_2009", "GOC:tb", "ISBN:0878932437" ]

null

[ "optic cup morphogenesis involved in camera-style eye development" ]

[ "EXACT" ]

[]

[ "GO:0016331" ]

[ "part_of GO:0060900" ]

[ "part_of" ]

[ "GO:0060900" ]

[ "GO:0016331", "GO:0060900" ]

[]

null

false

true

6

GO:0002074

2,074

extraocular skeletal muscle development

biological_process

The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with...

[ "GOC:dph", "GOC:mtg_muscle", "GOC:mtg_sensu", "MA:0001271", "PMID:16638982" ]

null

[]

[ "GO:0007519", "GO:0060538" ]

[ "part_of GO:0043010" ]

[ "part_of" ]

[ "GO:0043010" ]

[ "GO:0007519", "GO:0043010", "GO:0060538" ]

[]

null

false

true

5

GO:0002075

2,075

somitomeric trunk muscle development

biological_process

The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. ...

[ "GOC:dph", "PMID:16638982" ]

null

[]

[ "GO:0060538" ]

[]

[ "GO:0060538" ]

[]

null

false

true

3

GO:0002077

2,077

acrosome matrix dispersal

biological_process

The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosom...

[ "GOC:dph", "PMID:3886029" ]

null

[]

[ "GO:0030163" ]

[ "part_of GO:0007340" ]

[ "part_of" ]

[ "GO:0007340" ]

[ "GO:0007340", "GO:0030163" ]

[]

null

false

true

4

GO:0002078

2,078

membrane fusion involved in acrosome reaction

biological_process

The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.

[ "GOC:dph", "PMID:3886029" ]

null

[ "membrane fusion involved in the acrosomal reaction" ]

[ "EXACT" ]

[]

[ "GO:0022412", "GO:0061025" ]

[ "part_of GO:0007340" ]

[ "part_of" ]

[ "GO:0007340" ]

[ "GO:0007340", "GO:0022412", "GO:0061025" ]

[ "GO:0061025", "part_of GO:0007340" ]

[]

null

false

true

3

GO:0002079

2,079

inner acrosomal membrane

cellular_component

The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.

[ "GOC:dph", "PMID:3899643", "PMID:8936405" ]

Note that this term is not a descendant of 'organelle inner membrane ; GO:0019866' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.

[]

[ "GO:0030659" ]

[ "part_of GO:0002080" ]

[ "part_of" ]

[ "GO:0002080" ]

[ "GO:0002080", "GO:0030659" ]

[]

null

false

true

1

GO:0002080

2,080

acrosomal membrane

cellular_component

The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.

[ "GOC:dph" ]

null

[]

[ "GO:0030667" ]

[ "part_of GO:0001669" ]

[ "part_of" ]

[ "GO:0001669" ]

[ "GO:0001669", "GO:0030667" ]

[]

null

false

true

8

GO:0002081

2,081

outer acrosomal membrane

cellular_component

The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.

[ "GOC:dph", "PMID:8936405" ]

Note that this term is not a descendant of 'organelle outer membrane ; GO:0031968' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.

[]

[ "GO:0030659" ]

[ "part_of GO:0002080" ]

[ "part_of" ]

[ "GO:0002080" ]

[ "GO:0002080", "GO:0030659" ]

[]

null

false

true

6

GO:0002082

2,082

regulation of oxidative phosphorylation

biological_process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providin...

[ "GOC:dph" ]

null

[ "OXPHOS" ]

[ "EXACT" ]

[]

[ "GO:1903715" ]

[ "regulates GO:0006119" ]

[ "regulates" ]

[ "GO:0006119" ]

[ "GO:0006119", "GO:1903715" ]

[ "GO:0065007", "regulates GO:0006119" ]

[]

null

false

true

1

GO:0002083

2,083

obsolete 4-hydroxybenzoate decaprenyltransferase activity

molecular_function

OBSOLETE. Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.

[ "GOC:curators" ]

This term was obsoleted because it represents a specific substrate of 4-hydroxybenzoate polyprenyltransferase activity ; GO:0008412.

[]

[ "GO:0008412" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26830\" xsd:anyURI" ]

null

true

7

GO:0002084

2,084

protein depalmitoylation

biological_process

The removal of palymitoyl groups from a lipoprotein.

[ "GOC:hjd" ]

null

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0035601", "GO:0042159", "GO:0098734" ]

[]

[ "GO:0035601", "GO:0042159", "GO:0098734" ]

[]

null

false

true

8

GO:0002085

2,085

inhibition of neuroepithelial cell differentiation

biological_process

Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.

[ "GOC:dph", "PMID:16678814" ]

null

[ "negative regulation of neural plate formation", "repression of premature neural plate formation" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0022603", "GO:0030857", "GO:0045995", "GO:0048505" ]

[ "negatively_regulates GO:0060563" ]

[ "negatively_regulates" ]

[ "GO:0060563" ]

[ "GO:0022603", "GO:0030857", "GO:0045995", "GO:0048505", "GO:0060563" ]

[ "GO:0065007", "negatively_regulates GO:0060563" ]

[]

null

false

true

3

GO:0002086

2,086

diaphragm contraction

biological_process

A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP...

[ "GOC:dph", "GOC:mtg_muscle", "PMID:12458206" ]

null

[]

[ "GO:0003011", "GO:0003016" ]

[]

[ "GO:0003011", "GO:0003016" ]

[]

null

false

true

3

GO:0002087

2,087

regulation of respiratory gaseous exchange by nervous system process

biological_process

A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.

[ "GOC:dph", "GOC:tb", "PMID:12458206" ]

null

[ "neurological control of breathing", "regulation of respiratory gaseous exchange by neurological system process" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0044065", "GO:0050877" ]

[]

[ "GO:0044065", "GO:0050877" ]

[ "GO:0050877", "regulates GO:0007585" ]

[]

null

false

true

8

GO:0002088

2,088

lens development in camera-type eye

biological_process

The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.

[ "GOC:dph", "ISBN:0582064333" ]

null

[ "lens development", "lens development in camera-style eye" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0048856" ]

[ "part_of GO:0043010" ]

[ "part_of" ]

[ "GO:0043010" ]

[ "GO:0043010", "GO:0048856" ]

[]

null

false

true

1

GO:0002089

2,089

lens morphogenesis in camera-type eye

biological_process

The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.

[ "GOC:dph", "GOC:mtg_sensu" ]

null

[ "lens morphogenesis", "lens morphogenesis in camera-style eye" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0009653" ]

[ "part_of GO:0002088", "part_of GO:0048593" ]

[ "part_of", "part_of" ]

[ "GO:0002088", "GO:0048593" ]

[ "GO:0002088", "GO:0009653", "GO:0048593" ]

[]

null

false

true

5

GO:0002091

2,091

negative regulation of receptor internalization

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.

[ "GOC:hjd" ]

null

[ "down regulation of receptor internalization", "down-regulation of receptor internalization", "downregulation of receptor internalization", "inhibition of receptor internalization" ]

[ "EXACT", "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0002090", "GO:0048261" ]

[ "negatively_regulates GO:0031623" ]

[ "negatively_regulates" ]

[ "GO:0031623" ]

[ "GO:0002090", "GO:0031623", "GO:0048261" ]

[ "GO:0065007", "negatively_regulates GO:0031623" ]

[]

null

false

true

6

GO:0002093

2,093

auditory receptor cell morphogenesis

biological_process

Any process that alters the size or shape of an auditory receptor cell.

[ "GOC:dph", "GOC:tb" ]

null

[ "hair cell morphogenesis" ]

[ "BROAD" ]

[]

[ "GO:0048598", "GO:0048667" ]

[ "part_of GO:0042472", "part_of GO:0060117" ]

[ "part_of", "part_of" ]

[ "GO:0042472", "GO:0060117" ]

[ "GO:0042472", "GO:0048598", "GO:0048667", "GO:0060117" ]

[]

null

false

true

9

GO:0002094

2,094

obsolete polyprenyltransferase activity

molecular_function

OBSOLETE. Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).

[ "GOC:hjd" ]

The reason for obsoletion is that this term was an unnecessary grouping term.

[]

[ "GO:0004659" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29428\" xsd:anyURI" ]

null

true

3

GO:0002095

2,095

caveolar macromolecular signaling complex

cellular_component

A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).

[ "PMID:16648270" ]

null

[ "caveolar macromolecular signalling complex" ]

[ "EXACT" ]

[]

[ "GO:0098797" ]

[ "part_of GO:0005901" ]

[ "part_of" ]

[ "GO:0005901" ]

[ "GO:0005901", "GO:0098797" ]

[]

null

false

true

8

GO:0002096

2,096

polkadots

cellular_component

A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.

[ "PMID:14724296", "PMID:16495340" ]

Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.

[]

[ "GO:0032991" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0032991" ]

[]

null

false

true

5

GO:0002097

2,097

tRNA wobble base modification

biological_process

The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence (position 34) corresponds to the first position of the anticodon.

[ "PMID:28812932" ]

null

[]

[ "GO:0006400" ]

[]

[ "GO:0006400" ]

[]

null

false

true

4

GO:0002098

2,098

tRNA wobble uridine modification

biological_process

The process in which a uridine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence (position 34) corresponds to the first position of the anticodon.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0002097" ]

[]

[ "GO:0002097" ]

[]

null

false

true

9

GO:0002099

2,099

tRNA wobble guanine modification

biological_process

The process in which a guanine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence (position 34) corresponds to the first position of the anticodon.

[ "GOC:hjd", "PMID:39600051" ]

null

[]

[ "GO:0002097" ]

[]

[ "GO:0002097" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30774\" xsd:anyURI" ]

null

false

true

9

GO:0002100

2,100

tRNA wobble adenosine to inosine editing

biological_process

The process in which an adenosine at position 34 of a tRNA is post-transcriptionally converted to inosine. The wobble nucleoside of the tRNA sequence (position 34) corresponds to the first position of the anticodon.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0002097", "GO:0006382" ]

[]

[ "GO:0002097", "GO:0006382" ]

[]

null

false

true

8

GO:0002101

2,101

tRNA wobble cytosine modification

biological_process

The process in which a cytosine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence (position 34) corresponds to the first position of the anticodon.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0002097" ]

[]

[ "GO:0002097" ]

[]

null

false

true

1

GO:0002102

2,102

podosome

cellular_component

An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.

[ "PMID:12837608", "PMID:15890982" ]

Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring ...

[]

[ "Wikipedia:Podosome" ]

[ "GO:0043232" ]

[ "part_of GO:0015629" ]

[ "part_of" ]

[ "GO:0015629" ]

[ "GO:0015629", "GO:0043232" ]

[]

null

false

true

1

GO:0002103

2,103

endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

biological_process

Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this orde...

[ "GOC:curators" ]

null

[]

[ "GO:0006364" ]

[]

[ "GO:0006364" ]

[]

null

false

true

7

GO:0002104

2,104

endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

biological_process

Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the wor...

[ "GOC:curators" ]

null

[]

[ "GO:0002103" ]

[]

[ "GO:0002103" ]

[]

null

false

true

2

GO:0002105

2,105

endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

biological_process

Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the wo...

[ "GOC:curators" ]

null

[]

[ "GO:0002103" ]

[]

[ "GO:0002103" ]

[]

null

false

true

1

GO:0002106

2,106

endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

biological_process

Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tR...

[ "GOC:curators" ]

null

[]

[ "GO:0002103" ]

[]

[ "GO:0002103" ]

[]

null

false

true

9

GO:0002107

2,107

generation of mature 3'-end of 5S rRNA generated by RNA polymerase III

biological_process

The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.

[ "GOC:hjd", "PMID:16387655", "PMID:1748637", "PMID:1902221", "PMID:8389357" ]

null

[]

[ "GO:0000481", "GO:0031125" ]

[]

[ "GO:0000481", "GO:0031125" ]

[]

null

false

true

2

GO:0002108

2,108

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)

biological_process

Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3'...

[ "GOC:curators" ]

null

[]

[ "GO:0000470" ]

[]

[ "GO:0000470" ]

[]

null

false

true

2

GO:0002109

2,109

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)

biological_process

Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3'...

[ "GOC:curators" ]

null

[]

[ "GO:0030490" ]

[]

[ "GO:0030490" ]

[]

null

false

true

2

GO:0002110

2,110

cotranscriptional mitochondrial rRNA nucleotide insertion

biological_process

The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.

[ "GOC:curators", "ISBN:1555811337", "PMID:8306965" ]

null

[]

[ "GO:0000154", "GO:0070705" ]

[]

[ "GO:0000154", "GO:0070705" ]

[]

null

false

true

7

GO:0002111

2,111

BRCA2-BRAF35 complex

cellular_component

A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.

[ "GOC:hjd", "PMID:11207365" ]

null

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

null

false

true

6

GO:0002112

2,112

interleukin-33 receptor binding

molecular_function

Binding to an interleukin-33 receptor.

[ "GOC:hjd" ]

null

[ "IL-33", "interleukin-33 receptor ligand" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0005126" ]

[]

[ "GO:0005126" ]

[]

null

false

true

3

GO:0002113

2,113

interleukin-33 binding

molecular_function

Binding to interleukin-33.

[ "GOC:hjd" ]

null

[ "IL-33 binding" ]

[ "EXACT" ]

[]

[ "GO:0019955" ]

[]

[ "GO:0019955" ]

[]

null

false

true

3

GO:0002114

2,114

interleukin-33 receptor activity

molecular_function

Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:hjd", "GOC:signaling" ]

null

[ "IL-33 receptor activity", "IL-33R" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0004896" ]

[ "has_part GO:0002113", "part_of GO:0038172" ]

[ "has_part", "part_of" ]

[ "GO:0002113", "GO:0038172" ]

[ "GO:0002113", "GO:0004896", "GO:0038172" ]

[]

null

false

true

3

GO:0002115

2,115

store-operated calcium entry

biological_process

A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.

[ "GOC:hjd", "PMID:11120592", "PMID:17956991" ]

SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum.

[ "calcium ion import", "capacitative calcium entry", "SOCE", "store-operated calcium import" ]

[ "BROAD", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006816" ]

[]

[ "GO:0006816" ]

[]

null

false

true

4

GO:0002116

2,116

semaphorin receptor complex

cellular_component

A stable binary complex of a semaphorin and a plexin, together forming a functional semaphorin receptor.

[ "GOC:hjd", "PMID:10934324", "PMID:12367632", "PMID:12613544" ]

null

[ "plexin-neurophilin complex" ]

[ "EXACT" ]

[]

[ "GO:0043235" ]

[]

[ "GO:0043235" ]

[]

null

false

true

4

GO:0002117

2,117

amphibian larval development

biological_process

The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they ...

[ "GOC:bf", "PMID:27143402" ]

null

[]

[ "GO:0002164" ]

[]

[ "GO:0002164" ]

[]

null

false

true

7

GO:0002119

2,119

nematode larval development

biological_process

The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Eac...

[ "GOC:ems", "GOC:kmv" ]

null

[]

[ "GO:0002164" ]

[]

[ "GO:0002164" ]

[]

null

false

true

4

GO:0002120

2,120

obsolete predatory behavior

biological_process

OBSOLETE. Aggressive behavior involving attack on prey by a predator.

[ "GOC:hjd" ]

This term was obsoleted because it is outside the scope of GO.

[ "predatory aggression", "predatory aggressive behavior" ]

[ "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18568\" xsd:anyURI" ]

null

true

9

GO:0002121

2,121

inter-male aggressive behavior

biological_process

Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.

[ "GOC:hjd" ]

null

[ "inter-male aggression" ]

[ "EXACT" ]

[]

[ "GO:0002118" ]

[]

[ "GO:0002118" ]

[]

null

false

true

7

GO:0002122

2,122

fear-induced aggressive behavior

biological_process

Aggressive behavior associated with attempts to flee from a threat.

[ "GOC:hjd" ]

null

[ "fear-induced aggression" ]

[ "EXACT" ]

[]

[ "GO:0002118" ]

[]

[ "GO:0002118" ]

[]

null

false

true

2

GO:0002123

2,123

irritable aggressive behavior

biological_process

Aggressive behavior induced by frustration and directed against an available target.

[ "GOC:hjd" ]

null

[ "irritable aggression" ]

[ "EXACT" ]

[]

[ "GO:0002118" ]

[]

[ "GO:0002118" ]

[]

null

false

true

1

GO:0002124

2,124

territorial aggressive behavior

biological_process

Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.

[ "GOC:hjd" ]

null

[ "territorial aggression" ]

[ "EXACT" ]

[]

[ "GO:0002118" ]

[]

[ "GO:0002118" ]

[]

null

false

true

9

GO:0002125

2,125

maternal aggressive behavior

biological_process

Aggressive behavior of a female to protect her offspring from a threat.

[ "GOC:hjd" ]

Paternal aggression also exists. Serves to protect the offspring from intruders.

[ "maternal aggression" ]

[ "EXACT" ]

[]

[ "GO:0002118" ]

[]

[ "GO:0002118" ]

[]

null

false

true

9

GO:0002126

2,126

instrumental aggressive behavior

biological_process

Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation.

[ "GOC:hjd" ]

null

[ "instrumental aggression" ]

[ "EXACT" ]

[]

[ "GO:0002118" ]

[]

[ "GO:0002118" ]

[]

null

false

true

4

GO:0002127

2,127

tRNA wobble base cytosine methylation

biological_process

The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[ "wobble position m5C biosynthesis" ]

[ "EXACT" ]

[]

[ "GO:0002101", "GO:0002946" ]

[]

[ "GO:0002101", "GO:0002946" ]

[]

null

false

true

6

GO:0002128

2,128

tRNA nucleoside ribose methylation

biological_process

The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0030488" ]

[]

[ "GO:0030488" ]

[]

null

false

true

8

GO:0002129

2,129

wobble position guanine ribose methylation

biological_process

The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0002130", "GO:0002938" ]

[]

[ "GO:0002130", "GO:0002938" ]

[]

null

false

true

1

GO:0002130

2,130

wobble position ribose methylation

biological_process

The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0002128" ]

[]

[ "GO:0002128" ]

[]

null

false

true

6

GO:0002131

2,131

wobble position cytosine ribose methylation

biological_process

The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0002130" ]

[]

[ "GO:0002130" ]

[]

null

false

true

7

GO:0002132

2,132

wobble position uridine ribose methylation

biological_process

The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.

[ "GOC:hjd", "ISBN:155581073X" ]

null

[]

[ "GO:0002130" ]

[]

[ "GO:0002130" ]

[]

null

false

true

4

GO:0002133

2,133

polycystin complex

cellular_component

A stable heterodimeric complex composed of polycystin-1 and polycystin-2.

[ "GOC:hjd", "PMID:11901144" ]

Different forms of the complex differing in type of N-glycosylation of polycystin-1 can exist (endoglycosidase sensitive and endoglycosidase resistant).

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

null

false

true

2

GO:0002134

2,134

UTP binding

molecular_function

Binding to UTP, uridine 5'-triphosphate.

[ "GOC:hjd", "ISBN:0198506732" ]

null

[]

[ "GO:0032557", "GO:0043168" ]

[]

[ "GO:0032557", "GO:0043168" ]

[]

null

false

true

6

GO:0002135

2,135

CTP binding

molecular_function

Binding to CTP, cytidine 5'-triphosphate.

[ "GOC:hjd", "ISBN:0124020607" ]

null

[]

[ "GO:0032557", "GO:0043168" ]

[]

[ "GO:0032557", "GO:0043168" ]

[]

null

false

true

1

GO:0002136

2,136

tRNA wobble base lysidine biosynthesis

biological_process

The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.

[ "PMID:15894617" ]

Exclusively located at the anticodon wobble position (i.e., position 34) of eubacterial and some organellar tRNAIle2. This modification converts the codon specificity from AUG to AUA, and it also converts the aminoacylation specificity of the tRNA from methionine to isoleucine. Requires ATP.

[]

[ "GO:0002101" ]

[]

[ "GO:0002101" ]

[]

null

false

true

8

GO:0002138

2,138

retinoic acid biosynthetic process

biological_process

The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.

[ "GOC:hjd" ]

null

[ "retinoic acid anabolic process", "retinoic acid biosynthesis" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0016102", "GO:0042573", "GO:0072330" ]

[]

[ "GO:0016102", "GO:0042573", "GO:0072330" ]

[]

hjd

2009-05-01T10:53:24Z

false

true

2

GO:0002139

2,139

stereocilia coupling link

cellular_component

A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas an...

[ "PMID:16775142" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0032421" ]

[ "part_of" ]

[ "GO:0032421" ]

[ "GO:0032421", "GO:0110165" ]

[]

hjd

2009-05-06T10:25:38Z

false

true

7

GO:0002141

2,141

stereocilia ankle link

cellular_component

A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia.

[ "PMID:17567809" ]

null

[]

[ "GO:0002139" ]

[]

[ "GO:0002139" ]

[]

hjd

2009-05-06T10:31:56Z

false

true

2

GO:0002142

2,142

stereocilia ankle link complex

cellular_component

A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin.

[ "PMID:16775142" ]

null

[]

[ "GO:0032991" ]

[ "part_of GO:0002141" ]

[ "part_of" ]

[ "GO:0002141" ]

[ "GO:0002141", "GO:0032991" ]

[]

hjd

2009-05-06T10:33:57Z

false

true

8

GO:0002143

2,143

tRNA wobble position uridine thiolation

biological_process

The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.

[ "PMID:16871210" ]

In E. coli, the first step of the reaction is reductive elimination of sulfur from L-cysteine by IscS cysteine desulfurase to form an enzyme-bound cysteine-persulfide intermediate. Then, five essential gene products, TusA, TusB, TusC, TusD and TusE, mediate a sulfur relay that delivers the terminal sulfur of persulfide...

[ "tRNA wobble uridine thiolation", "wobble position s2U biosynthesis" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0002098", "GO:0034227" ]

[]

[ "GO:0002098", "GO:0034227" ]

[]

hjd

2009-05-06T05:05:40Z

false

true

9

GO:0002144

2,144

cytosolic tRNA wobble base thiouridylase complex

cellular_component

A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets.

[ "PMID:17062623", "PMID:18391219" ]

null

[ "Ctu1-Ctu2 complex", "tRNA thiouridylase" ]

[ "NARROW", "BROAD" ]

[]

[ "GO:0140535", "GO:1990228" ]

[]

[ "GO:0140535", "GO:1990228" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27929\" xsd:anyURI" ]

hjd

2009-05-08T02:32:55Z

false

true

2

GO:0002145

2,145

4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity

molecular_function

Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H+.

[ "MetaCyc:RXN0-3543" ]

null

[ "HMP-PP diphosphatase", "HMP-PP pyrophosphatase" ]

[ "EXACT", "EXACT" ]

[]

[ "MetaCyc:RXN0-3543", "RHEA:27914" ]

[ "GO:0016462" ]

[]

[ "GO:0016462" ]

[]

[ "skos:exactMatch RHEA:27914", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

hjd

2009-06-10T11:21:35Z

false

true

8

GO:0002146

2,146

obsolete steroid hormone receptor import into nucleus

biological_process

OBSOLETE. The directed movement of a steroid hormone receptor into the nucleus.

[ "GOC:hjd" ]

The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.

[ "steroid hormone receptor nuclear translocation" ]

[ "NARROW" ]

[]

[ "GO:0006606", "GO:0042306" ]

[]

hjd

2009-07-09T02:34:42Z

true

9

GO:0002147

2,147

obsolete glucocorticoid receptor import into nucleus

biological_process

OBSOLETE. The directed movement of a glucocorticoid receptor into the nucleus.

[ "GOC:hjd" ]

The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.

[ "glucocorticoid receptor nuclear translocation" ]

[ "NARROW" ]

[]

[ "GO:0042306" ]

[]

hjd

2009-07-09T02:36:09Z

true

9

GO:0002148

2,148

obsolete hypochlorous acid metabolic process

biological_process

OBSOLETE. The chemical reactions and pathways involving hypochlorous acid.

[ "GOC:add", "PMID:10085024", "PMID:176150" ]

This term was obsoleted because it is an unnecessary grouping class.

[ "HClO metabolic process", "HOCl metabolic process", "hypochlorite metabolic process", "hypochlorous acid metabolism" ]

[ "EXACT", "EXACT", "RELATED", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]

hjd

2009-10-13T10:27:48Z

true

1

GO:0002149

2,149

hypochlorous acid biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of hypochlorous acid.

[ "GOC:add", "PMID:10085024", "PMID:176150" ]

Note that this reaction is catalyzed by myeloperoxidase in neutrophils.

[ "HClO biosynthetic process", "HOCl biosynthetic process", "hypochlorite biosynthetic process", "hypochlorous acid biosynthesis" ]

[ "EXACT", "EXACT", "RELATED", "EXACT" ]

[]

[ "GO:0043436", "GO:0044283", "GO:1903409" ]

[]

[ "GO:0043436", "GO:0044283", "GO:1903409" ]

[]

hjd

2009-10-13T10:32:35Z

false

true

3

GO:0002150

2,150

hypochlorous acid catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.

[ "GOC:add" ]

null

[ "HClO catabolic process", "HOCl catabolic process", "hypochlorite catabolic process", "hypochlorous acid catabolism" ]

[ "EXACT", "EXACT", "RELATED", "EXACT" ]

[]

[ "GO:0043436", "GO:0044282", "GO:0072593" ]

[]

[ "GO:0043436", "GO:0044282", "GO:0072593" ]

[]

hjd

2009-10-13T10:36:09Z

false

true

6

GO:0002151

2,151

G-quadruplex RNA binding

molecular_function

Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.

[ "PMID:18294969", "PMID:18568163", "PMID:19330720" ]

The structures of RNA and DNA G quartets differ regarding sugar conformation so that a protein binding to the RNA structure might not bind to the DNA structure.

[ "G quadruplex binding", "G quartet binding", "G quartet RNA binding", "G-quartet binding" ]

[ "EXACT", "BROAD", "EXACT", "BROAD" ]

[]

[ "Reactome:R-HSA-9836998 \"GRSF1 unwinds quadruplex G regions in RNA\"" ]

[ "GO:0003723" ]

[]

[ "GO:0003723" ]

[]

hjd

2009-10-22T01:38:02Z

false

true

3

GO:0002152

2,152

bile acid conjugation

biological_process

The process in which bile acids are covalently linked to taurine or glycine.

[ "PMID:1094911", "PMID:708413" ]

The bile acid is first activated using CoA by cholate-CoA ligase activity(GO:0047747), then conjugated to taurine or glycine by glycine N-choloyltransferase activity (GO:0047963; appears to use either glycine or taurine).

[]

[ "GO:0008206" ]

[]

[ "GO:0008206" ]

[]

hjd

2009-10-29T01:41:51Z

false

true

8

GO:0002153

2,153

steroid receptor RNA activator RNA binding

molecular_function

Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.

[ "GOC:vw", "PMID:10199399", "PMID:15180993" ]

Note: there is also evidence that the RNA itself may code a protein (solution structure of mouse steroid receptor RNA activator 1 (SRA1) protein submitted to PDB by Riken).

[ "SRA binding" ]

[ "EXACT" ]

[]

[ "GO:0003727" ]

[]

[ "GO:0003727" ]

[]

hjd

2009-11-16T02:18:55Z

false

true

7

GO:0002154

2,154

thyroid hormone receptor signaling pathway

biological_process

A nuclear receptor-mediated signaling pathway initiated by a thyroid hormone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.

[ "GOC:hjd" ]

null

[ "thyroid hormone mediated signalling pathway" ]

[ "EXACT" ]

[]

[ "GO:0009755", "GO:0141193" ]

[]

[ "GO:0009755", "GO:0141193" ]

[]

hjd

2009-11-19T12:36:29Z

false

true

7

GO:0002156

2,156

negative regulation of thyroid hormone receptor signaling pathway

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.

[ "GOC:hjd" ]

null

[ "negative regulation of thyroid hormone mediated signaling pathway", "negative regulation of thyroid hormone mediated signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0002155", "GO:1902532" ]

[ "negatively_regulates GO:0002154" ]

[ "negatively_regulates" ]

[ "GO:0002154" ]

[ "GO:0002154", "GO:0002155", "GO:1902532" ]

[ "GO:0065007", "negatively_regulates GO:0002154" ]

[]

hjd

2009-11-19T12:41:48Z

false

true

7

GO:0002158

2,158

osteoclast proliferation

biological_process

The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.

[ "CL:0000092", "GOC:hjd" ]

null

[]

[ "GO:0070661" ]

[]

[ "GO:0070661" ]

[]

hjd

2010-02-03T01:50:37Z

false

true

7

GO:0002160

2,160

desmosome maintenance

biological_process

The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.

[ "GOC:hjd", "ISBN:0198506732" ]

Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix.

[]

[ "GO:0002934", "GO:0045217" ]

[]

[ "GO:0002934", "GO:0045217" ]

[]

hjd

2010-02-09T10:50:59Z

false

true

8

GO:0002161

2,161

aminoacyl-tRNA deacylase activity

molecular_function

The hydrolysis of an incorrectly aminoacylated tRNA.

[ "GOC:hjd", "PMID:14663147", "PMID:16087889" ]

null

[ "amino acid proofreading activity", "aminoacyl-tRNA editing activity", "aminoacyl-tRNA hydrolysis activity" ]

[ "RELATED", "EXACT", "RELATED" ]

[]

[ "GO:0052689", "GO:0140101", "GO:0160215" ]

[ "part_of GO:0106074" ]

[ "part_of" ]

[ "GO:0106074" ]

[ "GO:0052689", "GO:0106074", "GO:0140101", "GO:0160215" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29746\" xsd:anyURI" ]

hjd

2010-02-12T03:06:56Z

false

true

3

GO:0002162

2,162

dystroglycan binding

molecular_function

Binding to dystroglycan, a glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).

[ "GOC:hjd" ]

null

[ "alpha-dystroglycan binding", "beta-dystroglycan binding" ]

[ "NARROW", "NARROW" ]

[ "GO:0002163", "GO:0002166" ]

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

hjd

2010-02-22T02:17:58Z

false

true

4

GO:0002164

2,164

larval development

biological_process

The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.

[ "GOC:jid", "ISBN:0877795088" ]

null

[]

[ "GO:0007275", "GO:0009791" ]

[]

[ "GO:0007275", "GO:0009791" ]

[]

null

false

true

2

GO:0002165

2,165

instar larval or pupal development

biological_process

The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster.

[ "GOC:jid", "GOC:mtg_sensu" ]

null

[]

[ "GO:0007275", "GO:0009791" ]

[]

[ "GO:0007275", "GO:0009791" ]

[]

null

false

true

9