Datasets:
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GO

Dataset card Data Studio Files
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 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0140444
140,444
cytoskeleton-nuclear membrane anchor activity
molecular_function
The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane.
[ "PMID:16237665" ]
null
[ "cytoskeletal protein-nuclear membrane adaptor activity", "cytoskeletal protein-nuclear membrane anchor activity", "cytoskeleton nuclear membrane anchor activity", "nuclear membrane-cytoskeleton anchor activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043495" ]
[]
[]
[]
[ "GO:0043495" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18283\" xsd:anyURI" ]
pg
2020-03-24T14:57:59Z
false
true
1
GO:0140445
140,445
chromosome, telomeric repeat region
cellular_component
A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single str...
[ "PMID:11352055", "PMID:30208292" ]
null
[]
[]
[]
[]
[]
[ "GO:0000781" ]
[]
[]
[]
[ "GO:0000781" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19086\" xsd:anyURI" ]
pg
2020-03-27T13:29:16Z
false
true
1
GO:0140446
140,446
fumigermin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus.
[ "PMID:32083553" ]
null
[ "fumigermin anabolism", "fumigermin biosynthesis", "fumigermin formation", "fumigermin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030639", "GO:1901336" ]
[]
[]
[]
[ "GO:0030639", "GO:1901336" ]
[]
[]
[]
[]
[]
[]
pg
2020-03-31T12:02:29Z
false
true
2
GO:0140447
140,447
cytokine precursor processing
biological_process
The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine.
[ "PMID:29247995" ]
null
[ "interleukin maturation", "interleukin processing" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0140448" ]
[ "part_of GO:0001816" ]
[ "part_of" ]
[ "GO:0001816" ]
[ "GO:0001816", "GO:0140448" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19216\" xsd:anyURI" ]
pg
2020-04-03T12:49:29Z
false
true
6
GO:0140448
140,448
signaling receptor ligand precursor processing
biological_process
The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.
[ "PMID:29247995" ]
null
[ "ligand maturation", "signal maturation" ]
[ "NARROW", "RELATED" ]
[ "GO:0035638" ]
[]
[]
[ "GO:0016485" ]
[]
[]
[]
[ "GO:0016485" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19216\" xsd:anyURI" ]
pg
2020-04-03T13:30:04Z
false
true
5
GO:0140449
140,449
centromere-nuclear envelope anchor activity
molecular_function
The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.
[ "PMID:31635174" ]
null
[ "centromere nuclear envelope anchor activity", "centromere nuclear envelope tether activity", "centromere-inner nuclear envelope anchor activity", "centromere-inner nuclear envelope tether activity", "chromosome, centromeric region-nuclear envelope anchor activity", "nuclear envelope-centromere anchor act...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043495" ]
[ "part_of GO:0072766" ]
[ "part_of" ]
[ "GO:0072766" ]
[ "GO:0043495", "GO:0072766" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19227\" xsd:anyURI" ]
pg
2020-04-07T06:27:08Z
false
true
4
GO:0140450
140,450
protein targeting to Golgi apparatus
biological_process
The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).
[ "PMID:18817523" ]
null
[]
[]
[]
[]
[]
[ "GO:0006605", "GO:0072594" ]
[]
[]
[]
[ "GO:0006605", "GO:0072594" ]
[]
[]
[]
[]
[]
[]
pg
2020-04-08T13:10:10Z
false
true
3
GO:0140453
140,453
protein aggregate center
cellular_component
Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.
[ "PMID:32075773" ]
null
[ "PAC", "protein aggregate centre" ]
[ "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0043232" ]
[]
[]
[]
[ "GO:0043232" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19172\" xsd:anyURI" ]
pg
2020-04-20T15:21:55Z
false
true
8
GO:0140454
140,454
protein aggregate center assembly
biological_process
The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.
[ "PMID:32075773" ]
null
[ "PAC assembly", "protein aggregate center formation", "protein aggregate centre assembly" ]
[ "BROAD", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19172\" xsd:anyURI" ]
pg
2020-04-20T15:43:52Z
false
true
8
GO:0140455
140,455
cytoplasm protein quality control
biological_process
The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.
[ "PMID:32075773" ]
null
[]
[]
[]
[]
[]
[ "GO:0006515" ]
[]
[]
[]
[ "GO:0006515" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19172\" xsd:anyURI" ]
pg
2020-04-20T15:46:20Z
false
true
3
GO:0140456
140,456
initial meiotic spindle pole body separation
biological_process
The release of duplicated meiotic spindle pole bodies (SPBs).
[ "PMID:31532702" ]
null
[ "initial spindle pole body separation involved in meiosis I", "meiotic spindle pole body duplication" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0110100", "GO:1903046" ]
[]
[]
[]
[ "GO:0110100", "GO:1903046" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17971\" xsd:anyURI" ]
pg
2020-04-22T19:07:22Z
false
true
6
GO:0140457
140,457
protein demethylase activity
molecular_function
Catalysis of the removal of a methyl group from a protein.
[ "PMID:24498420", "PMID:28360925" ]
null
[]
[]
[]
[]
[]
[ "GO:0032451", "GO:0140096" ]
[]
[]
[]
[ "GO:0032451", "GO:0140096" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19325\" xsd:anyURI" ]
pg
2020-04-23T07:39:14Z
false
true
9
GO:0140459
140,459
response to Gram-positive bacterium
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium.
[ "PMID:23664307" ]
null
[]
[]
[]
[]
[]
[ "GO:0009617" ]
[]
[]
[]
[ "GO:0009617" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19278\" xsd:anyURI" ]
pg
2020-04-30T07:33:34Z
false
true
8
GO:0140460
140,460
response to Gram-negative bacterium
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium.
[ "PMID:23664307" ]
null
[]
[]
[]
[]
[]
[ "GO:0009617" ]
[]
[]
[]
[ "GO:0009617" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19278\" xsd:anyURI" ]
pg
2020-04-30T07:34:38Z
false
true
9
GO:0140462
140,462
obsolete pericentric heterochromatin organization
biological_process
OBSOLETE. The organization of chromatin into heterochromatin at the pericentric region of a chromosome.
[ "PMID:26744419" ]
The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19396\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31331\" xsd:anyURI" ]
pg
2020-05-06T07:47:09Z
true
true
5
GO:0140463
140,463
chromatin-protein adaptor activity
molecular_function
An adaptor activity that brings together a protein and a region of the chromatin, such as a nucleosome, to establish or maintain the chromatin localization of the protein, or the complex to which it belongs.
[ "PMID:32277274" ]
null
[ "chromatin adaptor", "chromatin adaptor activity", "chromatin receptor", "chromatin recruitment", "chromatin-protein adaptor", "protein-chromatin adaptor activity" ]
[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030674" ]
[ "has_part GO:0003682", "part_of GO:0006325" ]
[ "has_part", "part_of" ]
[ "GO:0003682", "GO:0006325" ]
[ "GO:0003682", "GO:0006325", "GO:0030674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17064\" xsd:anyURI" ]
pg
2020-05-08T12:31:39Z
false
true
9
GO:0140464
140,464
subnuclear spatial organization of silent mating-type cassette heterochromatin
biological_process
The localization of silent mating-type cassette heterochromatin at a specific location in the nucleus.
[ "PMID:26744419" ]
null
[ "silent mating-type cassette heterochromatin organization", "silent mating-type cassette heterochromatin spatial organization in the nucleus" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0097240" ]
[]
[]
[]
[ "GO:0097240" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19396\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23785\" xsd:anyURI" ]
pg
2020-05-13T05:13:24Z
false
true
4
GO:0140466
140,466
iron-sulfur cluster export from the mitochondrion
biological_process
The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.
[ "PMID:31040179" ]
null
[]
[]
[]
[]
[]
[ "GO:0010496", "GO:1902497" ]
[]
[]
[]
[ "GO:0010496", "GO:1902497" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19504\" xsd:anyURI" ]
pg
2020-05-22T10:01:36Z
false
true
6
GO:0140467
140,467
integrated stress response signaling
biological_process
The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decr...
[ "PMID:27629041" ]
null
[ "ISR" ]
[ "RELATED" ]
[]
[]
[ "Wikipedia:Integrated_stress_response" ]
[ "GO:0033554", "GO:0141124" ]
[]
[]
[]
[ "GO:0033554", "GO:0141124" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19153\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27550\" xsd:anyURI" ]
pg
2020-05-26T08:04:10Z
false
true
1
GO:0140468
140,468
HRI-mediated signaling
biological_process
A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.
[ "PMID:27629041" ]
null
[ "EIF2AK1-mediated signaling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140467" ]
[]
[]
[]
[ "GO:0140467" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19153\" xsd:anyURI" ]
pg
2020-05-26T08:46:15Z
false
true
4
GO:0140469
140,469
GCN2-mediated signaling
biological_process
A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation.
[ "PMID:27629041" ]
null
[ "EIF2AK4-mediated signaling", "regulation of eIF2 alpha phosphorylation by amino acid starvation" ]
[ "EXACT", "NARROW" ]
[ "GO:0060733" ]
[]
[]
[ "GO:0140467" ]
[]
[]
[]
[ "GO:0140467" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15399\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19153\" xsd:anyURI" ]
pg
2020-05-26T08:47:25Z
false
true
3
GO:0140471
140,471
positive regulation of transepithelial migration of symbiont in host
biological_process
Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host.
[ "PMID:29113016" ]
null
[ "positive regulation of symbiont-mediated migration across host transepithelium", "positive regulation of symbiont-mediated migration through host transepithelium", "positive regulation of transmigration of symbiont in host" ]
[ "EXACT", "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0043903", "GO:0048518" ]
[ "positively_regulates GO:0035756" ]
[ "positively_regulates" ]
[ "GO:0035756" ]
[ "GO:0035756", "GO:0043903", "GO:0048518" ]
[ "GO:0065007", "positively_regulates GO:0035756" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19601\" xsd:anyURI" ]
pg
2020-06-11T15:32:38Z
false
true
9
GO:0140472
140,472
cell cortex of non-growing cell tip
cellular_component
The region directly beneath the plasma membrane at the cell tip at which no growth takes place.
[ "PMID:17895368" ]
null
[]
[]
[]
[]
[]
[ "GO:0051285" ]
[ "part_of GO:0035839" ]
[ "part_of" ]
[ "GO:0035839" ]
[ "GO:0035839", "GO:0051285" ]
[ "GO:0099738", "part_of GO:0035839" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17249\" xsd:anyURI" ]
pg
2020-06-18T13:33:58Z
false
true
3
GO:0140474
140,474
mitochondrion-endoplasmic reticulum membrane tether activity
molecular_function
The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.
[ "PMID:19556461", "PMID:27875684" ]
null
[ "endoplasmic reticulum-mitochondrion membrane adaptor activity", "endoplasmic reticulum-mitochondrion membrane tether activity", "ER-mitochondrion membrane adaptor activity", "ER-mitochondrion membrane tether activity", "mitochondrion-endoplasmic reticulum membrane adaptor activity", "mitochondrion-ER mem...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0170009" ]
[]
[]
[]
[ "GO:0170009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19634\" xsd:anyURI" ]
pg
2020-06-22T07:01:14Z
false
true
8
GO:0140475
140,475
spindle pole body anchor activity
molecular_function
The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.
[ "PMID:19942852" ]
null
[]
[]
[]
[]
[]
[ "GO:0008093" ]
[]
[]
[]
[ "GO:0008093" ]
[]
[]
[]
[]
[]
[]
pg
2020-06-23T15:54:56Z
false
true
6
GO:0140479
140,479
ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase
biological_process
A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide.
[ "PMID:22209968", "PMID:24828577" ]
null
[]
[]
[]
[]
[]
[ "GO:0052699" ]
[]
[]
[]
[ "GO:0052699" ]
[]
[]
[]
[]
[]
[]
pg
2020-06-25T09:58:21Z
false
true
4
GO:0140480
140,480
mitotic spindle pole body insertion into the nuclear envelope
biological_process
A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane.
[ "PMID:19487457", "PMID:24529240" ]
null
[ "establishment of spindle pole body localisation in nuclear envelope", "establishment of spindle pole body localization in nuclear envelope", "establishment of spindle pole body localization to nuclear envelope" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990608" ]
[]
[]
[]
[ "GO:1990608" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14887\" xsd:anyURI" ]
pg
2020-06-25T14:45:40Z
false
true
5
GO:0140481
140,481
ABC-type iron-sulfur cluster transporter activity
molecular_function
Catalysis of the reaction: ATP + H2O + iron-sulfur cluster(in) = ADP + phosphate + iron-sulfur cluster(out).
[ "PMID:31040179" ]
null
[ "ATPase-coupled Fe-S cluster transmembrane transporter activity", "ATPase-coupled iron-sulfur cluster transmembrane transporter activity" ]
[ "EXACT", "RELATED" ]
[]
[]
[ "TC:3.A.1.210.1" ]
[ "GO:0140359" ]
[]
[]
[]
[ "GO:0140359" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19685\" xsd:anyURI" ]
pg
2020-06-25T17:41:01Z
false
true
3
GO:0140482
140,482
iron sensor activity
molecular_function
Binding to and responding, e.g. by conformational change, to changes in the cellular level of iron.
[ "PMID:11956219", "PMID:25806539" ]
null
[]
[]
[]
[]
[]
[ "GO:0140784" ]
[]
[]
[]
[ "GO:0140784" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19433\" xsd:anyURI" ]
pg
2020-06-25T20:58:02Z
false
true
3
GO:0140483
140,483
kinetochore adaptor activity
molecular_function
The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way.
[ "PMID:22521786" ]
null
[ "inner kinetochore adaptor activity", "outer kinetochore adaptor activity" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0030674" ]
[]
[]
[]
[ "GO:0030674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19701\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21091\" xsd:anyURI" ]
pg
2020-06-29T08:53:10Z
false
true
3
GO:0140484
140,484
5-aminolevulinic acid import across plasma membrane
biological_process
The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol.
[ "PMID:31989647" ]
null
[]
[]
[]
[]
[]
[ "GO:0015695", "GO:0015718", "GO:0071705", "GO:0089718", "GO:1905039" ]
[]
[]
[]
[ "GO:0015695", "GO:0015718", "GO:0071705", "GO:0089718", "GO:1905039" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19527\" xsd:anyURI" ]
pg
2020-06-29T08:59:24Z
false
true
2
GO:0140485
140,485
5-aminolevulinic acid transmembrane transporter activity
molecular_function
Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other.
[ "PMID:31989647" ]
null
[]
[]
[]
[]
[]
[ "GO:0008028", "GO:0015171" ]
[]
[]
[]
[ "GO:0008028", "GO:0015171" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19527\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27521\" xsd:anyURI" ]
pg
2020-06-29T09:02:26Z
false
true
8
GO:0140486
140,486
zinc ion sequestering activity
molecular_function
Binding to a zinc ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
[ "PMID:12050156" ]
null
[]
[]
[]
[]
[]
[ "GO:0140487" ]
[ "has_part GO:0008270" ]
[ "has_part" ]
[ "GO:0008270" ]
[ "GO:0008270", "GO:0140487" ]
[ "GO:0140313", "has_part GO:0008270" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19700\" xsd:anyURI" ]
pg
2020-06-29T09:21:42Z
false
true
9
GO:0140487
140,487
metal ion sequestering activity
molecular_function
Binding to a metal ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
[ "PMID:12050156" ]
null
[]
[]
[]
[]
[]
[ "GO:0140313" ]
[ "has_part GO:0046872" ]
[ "has_part" ]
[ "GO:0046872" ]
[ "GO:0046872", "GO:0140313" ]
[ "GO:0140313", "has_part GO:0046872" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19700\" xsd:anyURI" ]
pg
2020-06-29T09:23:47Z
false
true
1
GO:0140488
140,488
heme receptor activity
molecular_function
Binding specifically to heme to deliver it to a transport vesicle.
[ "PMID:28193844", "PMID:32185489" ]
null
[]
[]
[]
[]
[]
[ "GO:0038024" ]
[]
[]
[]
[ "GO:0038024" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19699\" xsd:anyURI" ]
pg
2020-06-29T14:16:16Z
false
true
1
GO:0140489
140,489
molecular template activity
molecular_function
The action of a molecule that provides a shape or a sequence mimicking or complementary to the final product, providing template for copying the original molecule's shape or sequence.
[ "GOC:pg" ]
null
[]
[]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19709\" xsd:anyURI" ]
pg
2020-07-01T08:42:18Z
false
true
1
GO:0140490
140,490
microtubule nucleator activity
molecular_function
The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly.
[ "PMID:20631709", "PMID:21993292" ]
null
[ "microtubule nucleation template activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140489" ]
[]
[]
[]
[ "GO:0140489" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19709\" xsd:anyURI" ]
pg
2020-07-01T08:47:54Z
false
true
7
GO:0140492
140,492
metal-dependent deubiquitinase activity
molecular_function
An metal-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
[ "PMID:19489724" ]
null
[ "metal-dependent ubiquitin-like hydrolase activity", "metal-dependent ubiquitinyl-like hydrolase activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008237", "GO:0101005" ]
[]
[]
[]
[ "GO:0008237", "GO:0101005" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17398\" xsd:anyURI" ]
pg
2020-07-01T13:14:00Z
false
true
5
GO:0140493
140,493
very long-chain fatty acid beta-oxidation
biological_process
A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to ...
[ "GOC:ha", "PMID:17028011", "PMID:32169171" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[]
[]
[]
[]
[]
[ "GO:0033540", "GO:0042760" ]
[]
[]
[]
[ "GO:0033540", "GO:0042760" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19735\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26445\" xsd:anyURI" ]
pg
2020-07-10T08:39:22Z
false
true
1
GO:0140494
140,494
migrasome
cellular_component
A vesicular organelle that forms on retraction fibers behind migrating cells and mediates the release of cytoplasmic contents during cell migration.
[ "PMID:25342562", "PMID:31371827" ]
null
[]
[]
[]
[]
[]
[ "GO:0043231" ]
[]
[]
[]
[ "GO:0043231" ]
[]
[]
[]
[]
[]
[]
pg
2020-07-10T15:09:40Z
false
true
3
GO:0140495
140,495
migracytosis
biological_process
A cell migration-dependent mechanism for releasing cellular contents.
[ "PMID:25342562" ]
null
[]
[]
[]
[]
[]
[ "GO:0140352" ]
[]
[]
[]
[ "GO:0140352" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19760\" xsd:anyURI" ]
pg
2020-07-10T15:13:46Z
false
true
1
GO:0140496
140,496
gamma-tubulin complex binding
molecular_function
Binding to a gamma-tubulin complex.
[ "PMID:30174135" ]
null
[]
[]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19788\" xsd:anyURI" ]
pg
2020-07-17T08:14:32Z
false
true
4
GO:0140497
140,497
mannan polymerase II complex
cellular_component
A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p.
[ "PMID:9430634" ]
null
[]
[]
[]
[]
[]
[ "GO:0000136" ]
[]
[]
[]
[ "GO:0000136" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19817\" xsd:anyURI" ]
pg
2020-07-22T14:33:57Z
false
true
4
GO:0140499
140,499
negative regulation of mitotic spindle assembly checkpoint signaling
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling.
[ "PMID:28017606" ]
null
[]
[]
[]
[]
[]
[ "GO:0010948", "GO:0045842", "GO:0062033", "GO:0090233", "GO:0090266" ]
[ "negatively_regulates GO:0007094" ]
[ "negatively_regulates" ]
[ "GO:0007094" ]
[ "GO:0007094", "GO:0010948", "GO:0045842", "GO:0062033", "GO:0090233", "GO:0090266" ]
[ "GO:0065007", "negatively_regulates GO:0007094" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19818\" xsd:anyURI" ]
pg
2020-07-22T15:44:06Z
false
true
8
GO:0140500
140,500
regulation of reticulophagy
biological_process
Any process that modulates the frequency, rate or extent of reticulophagy.
[ "PMID:32735772" ]
null
[ "regulation of autophagy of the endoplasmic reticulum", "regulation of autophagy of the ER", "regulation of endoplasmic reticulum autophagy", "regulation of endoplasmic reticulum degradation", "regulation of ER autophagy", "regulation of ER degradation", "regulation of ER-phagy" ]
[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0016241" ]
[ "regulates GO:0061709" ]
[ "regulates" ]
[ "GO:0061709" ]
[ "GO:0016241", "GO:0061709" ]
[ "GO:0065007", "regulates GO:0061709" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19860\" xsd:anyURI" ]
pg
2020-08-10T12:01:22Z
false
true
6
GO:0140501
140,501
positive regulation of reticulophagy
biological_process
Any process that increases the frequency, rate or extent of reticulophagy.
[ "PMID:32735772" ]
null
[ "positive regulation of autophagy of the endoplasmic reticulum", "positive regulation of autophagy of the ER", "positive regulation of endoplasmic reticulum autophagy", "positive regulation of endoplasmic reticulum degradation", "positive regulation of ER autophagy", "positive regulation of ER degradation...
[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0016239", "GO:0140500" ]
[ "positively_regulates GO:0061709" ]
[ "positively_regulates" ]
[ "GO:0061709" ]
[ "GO:0016239", "GO:0061709", "GO:0140500" ]
[ "GO:0065007", "positively_regulates GO:0061709" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19860\" xsd:anyURI" ]
pg
2020-08-10T12:01:35Z
false
true
5
GO:0140502
140,502
effector-mediated suppression of host salicylic acid-mediated innate immune signaling
biological_process
A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signaling.
[ "PMID:25438793", "PMID:30651637" ]
null
[ "effector-mediated disruption of host salicylic acid-mediated innate immune signalling", "effector-mediated suppression of host salicylic acid-mediated innate immune signalling" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0052003", "GO:0052029", "GO:0140404" ]
[]
[]
[]
[ "GO:0052003", "GO:0052029", "GO:0140404" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19848\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28790\" xsd:anyURI" ]
pg
2020-08-11T06:16:36Z
false
true
5
GO:0140504
140,504
microlipophagy
biological_process
Degradation of a lipid droplet by microautophagy.
[ "PMID:25070953", "PMID:28394250", "PMID:28838958", "PMID:29293450", "PMID:29601311" ]
null
[ "lipid droplet autophagy" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0016237" ]
[]
[]
[]
[ "GO:0016237" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19869\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25541\" xsd:anyURI" ]
pg
2020-08-14T12:53:43Z
false
true
8
GO:0140505
140,505
regulation of microlipophagy
biological_process
Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion.
[ "PMID:28394250", "PMID:29601311" ]
null
[]
[]
[]
[]
[]
[ "GO:0010506" ]
[ "regulates GO:0140504" ]
[ "regulates" ]
[ "GO:0140504" ]
[ "GO:0010506", "GO:0140504" ]
[ "GO:0065007", "regulates GO:0140504" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19869\" xsd:anyURI" ]
pg
2020-08-14T12:56:29Z
false
true
7
GO:0140506
140,506
endoplasmic reticulum-autophagosome adaptor activity
molecular_function
The binding activity of a molecule that brings together an ER membrane and an autophagosome during reticulophagy.
[ "PMID:32735772" ]
null
[ "autophagosome-endoplasmic reticulum anchor", "autophagosome-ER anchor", "ER- autophagosome anchor" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0160183", "GO:0170009" ]
[]
[]
[]
[ "GO:0160183", "GO:0170009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19873\" xsd:anyURI" ]
pg
2020-08-27T11:04:43Z
false
true
8
GO:0140507
140,507
granzyme-mediated programmed cell death signaling pathway
biological_process
The series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cel...
[ "PMID:32299851" ]
null
[ "granzyme-mediated cell death signaling pathway" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0007165" ]
[ "part_of GO:0012501" ]
[ "part_of" ]
[ "GO:0012501" ]
[ "GO:0007165", "GO:0012501" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"http://wiki.geneontology.org/index.php/Apoptosis_Curation_Manual#Other_children_of_apoptotic_signaling_pathway\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19901\" xsd:anyURI" ]
pg
2020-08-27T13:51:40Z
false
true
3
GO:0140509
140,509
epithelium-like organization
biological_process
The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins.
[ "PMID:21393547", "PMID:22902739" ]
null
[]
[]
[]
[]
[]
[ "GO:0009653" ]
[]
[]
[]
[ "GO:0009653" ]
[]
[]
[]
[]
[]
[]
pg
2020-08-28T07:29:53Z
false
true
9
GO:0140510
140,510
mitotic nuclear bridge
cellular_component
A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei.
[ "PMID:32848252" ]
null
[ "nuclear bridge" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005634" ]
[ "part_of" ]
[ "GO:0005634" ]
[ "GO:0005634", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pg
2020-09-07T09:59:46Z
false
true
4
GO:0140511
140,511
mitotic nuclear bridge stalk
cellular_component
Either of the regions of a mitotic nuclear bridge proximal to the main portion of each daughter nucleus. The nuclear envelope in the stalk regions is depleted of nuclear pore complexes.
[ "PMID:32848252" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0140510" ]
[ "part_of" ]
[ "GO:0140510" ]
[ "GO:0110165", "GO:0140510" ]
[]
[]
[]
[]
[]
[]
pg
2020-09-07T10:06:23Z
false
true
6
GO:0140515
140,515
mitotic nuclear bridge organization
biological_process
A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis.
[ "PMID:32848252" ]
null
[]
[]
[]
[]
[]
[ "GO:0101024" ]
[]
[]
[]
[ "GO:0101024" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19948\" xsd:anyURI" ]
pg
2020-09-09T14:04:33Z
false
true
5
GO:0140516
140,516
mitotic nuclear pore complex disassembly
biological_process
The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis.
[ "PMID:32848252" ]
null
[ "nuclear pore complex disassembly during mitosis" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006999", "GO:0007077", "GO:0032984" ]
[]
[]
[]
[ "GO:0006999", "GO:0007077", "GO:0032984" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19947\" xsd:anyURI" ]
pg
2020-09-09T15:29:01Z
false
true
2
GO:0140522
140,522
fusogenic activity
molecular_function
The activity of joining two lipid bilayers to form a single membrane.
[ "PMID:10332732", "PMID:11493675", "PMID:12600315", "PMID:32100701", "PMID:32641474" ]
null
[]
[]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19942\" xsd:anyURI" ]
pg
2020-09-24T09:45:21Z
false
true
9
GO:0140523
140,523
GTPase-dependent fusogenic activity
molecular_function
A GTPase activity that mediates the joining of two lipid bilayers to form a single membrane.
[ "PMID:29663589" ]
null
[ "membrane fusion GTPase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0003924", "GO:0140522" ]
[ "part_of GO:0061025" ]
[ "part_of" ]
[ "GO:0061025" ]
[ "GO:0003924", "GO:0061025", "GO:0140522" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19942\" xsd:anyURI" ]
pg
2020-09-24T09:49:40Z
false
true
9
GO:0140526
140,526
double membrane vesicle viral factory assembly
biological_process
A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle.
[ "PMID:32555292" ]
null
[]
[]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19943\" xsd:anyURI" ]
pg
2020-09-29T08:26:51Z
false
true
6
GO:0140527
140,527
reciprocal homologous recombination
biological_process
A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules.
[ "PMID:17846636" ]
null
[]
[]
[]
[]
[]
[ "GO:0035825" ]
[]
[]
[]
[ "GO:0035825" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18777\" xsd:anyURI" ]
pg
2020-09-29T15:08:11Z
false
true
1
GO:0140528
140,528
bilobe structure assembly
biological_process
The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).
[ "PMID:18443217", "PMID:32675283" ]
null
[ "bilobe structure biogenesis", "bilobe structure formation", "kinetoplastid flagellar hook complex assembly" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0022607" ]
[ "part_of GO:0007010" ]
[ "part_of" ]
[ "GO:0007010" ]
[ "GO:0007010", "GO:0022607" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20057\" xsd:anyURI" ]
pg
2020-09-30T08:47:39Z
false
true
1
GO:0140530
140,530
MCM complex loading
biological_process
The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-d...
[ "PMID:23603117", "PMID:28191893", "PMID:28191894", "PMID:28501329" ]
null
[ "MCM complex loading at replication origin", "MCM double hexamer formation at replication origin" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0022402", "GO:0065004" ]
[ "part_of GO:1902315" ]
[ "part_of" ]
[ "GO:1902315" ]
[ "GO:0022402", "GO:0065004", "GO:1902315" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16570\" xsd:anyURI" ]
pg
2020-10-12T16:46:23Z
false
true
3
GO:0140531
140,531
obsolete regulation of osmosensory signaling MAPK cascade
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of osmosensory signaling MAPK cascade.
[ "PMID:31911490" ]
This term was obsoleted because it represents the same process as regulation of p38MAPK cascade ; GO:1900744.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:1900744" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20162\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26610\" xsd:anyURI" ]
pg
2020-10-20T15:38:10Z
true
true
9
GO:0140532
140,532
obsolete negative regulation of osmosensory signaling MAPK cascade
biological_process
OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade.
[ "PMID:31911490" ]
This term was obsoleted because it represents the same process as negative regulation of p38MAPK cascade ; GO:1903753.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:1903753" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20162\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26610\" xsd:anyURI" ]
pg
2020-10-20T15:39:24Z
true
true
1
GO:0140533
140,533
symbiont-mediated suppression of host RNAi-mediated antiviral immune response
biological_process
A process by which a symbiont inhibits or disrupts the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
[ "PMID:17693253" ]
null
[ "suppression of host RNAi-mediated antiviral immune response", "suppression of host RNAi-mediated antiviral immunity", "suppression of host RNAi-mediated gene silencing" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0052170" ]
[]
[]
[]
[ "GO:0052170" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19958\" xsd:anyURI" ]
pg
2020-10-28T07:55:27Z
false
true
7
GO:0140534
140,534
endoplasmic reticulum protein-containing complex
cellular_component
A protein complex that is part of an endoplasmic reticulum.
[ "GOC:pg" ]
null
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0005783" ]
[ "part_of" ]
[ "GO:0005783" ]
[ "GO:0005783", "GO:0032991" ]
[ "GO:0032991", "part_of GO:0005783" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19952\" xsd:anyURI" ]
pg
2020-10-28T12:14:12Z
false
true
9
GO:0140536
140,536
obsolete nuclear receptor corepressor activity
molecular_function
OBSOLETE. A transcription corepressor activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Nuclear receptor corepressors often act by altering chromatin structure and modifications. For example, one class of ...
[ "PMID:7566114", "PMID:7566126", "PMID:9238851" ]
The reason for obsoletion is that these activities are not necessarily specific for nuclear receptors subclass of dbTFs, so that distinction leads to misannotations.
[ "nuclear corepressor activity" ]
[ "BROAD" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0003714" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20262\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20464\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29150\" xsd:anyURI" ]
pg
2020-11-03T13:02:08Z
true
true
5
GO:0140537
140,537
transcription regulator activator activity
molecular_function
A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification.
[ "PMID:9597751" ]
Usage guidance: transcription regulator activators bind to a transcription regulator to allow it to reach the chromatin or to contact other transcriptional regulators. This activity does not occur at the promoter. For activities that do occur at the promoter, consider GO:0001216 ; DNA-binding transcription activator ac...
[]
[]
[]
[]
[]
[ "GO:0140677" ]
[ "part_of GO:0010468", "positively_regulates GO:0140110" ]
[ "part_of", "positively_regulates" ]
[ "GO:0010468", "GO:0140110" ]
[ "GO:0010468", "GO:0140110", "GO:0140677" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16132\" xsd:anyURI" ]
pg
2020-11-03T14:04:59Z
false
true
5
GO:0140538
140,538
negative regulation of conjugation with zygote
biological_process
A process that prevents a zygote from fusing an additional cell.
[ "PMID:30089908" ]
null
[]
[]
[]
[]
[]
[ "GO:0031138" ]
[]
[]
[]
[ "GO:0031138" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16329\" xsd:anyURI" ]
pg
2020-11-07T07:50:23Z
false
true
4
GO:0140539
140,539
regulation of melanotic encapsulation of foreign target
biological_process
Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target.
[ "PMID:15749104", "PMID:18457993" ]
null
[]
[]
[]
[]
[]
[ "GO:0002697", "GO:0035007" ]
[ "regulates GO:0035011" ]
[ "regulates" ]
[ "GO:0035011" ]
[ "GO:0002697", "GO:0035007", "GO:0035011" ]
[ "GO:0065007", "regulates GO:0035011" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16749\" xsd:anyURI" ]
pg
2020-11-07T08:16:00Z
false
true
8
GO:0140540
140,540
negative regulation melanotic encapsulation of foreign target
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.
[ "PMID:15749104", "PMID:18457993" ]
null
[]
[]
[]
[]
[]
[ "GO:0002698", "GO:0035009", "GO:0140539" ]
[ "negatively_regulates GO:0035011" ]
[ "negatively_regulates" ]
[ "GO:0035011" ]
[ "GO:0002698", "GO:0035009", "GO:0035011", "GO:0140539" ]
[ "GO:0065007", "negatively_regulates GO:0035011" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16749\" xsd:anyURI" ]
pg
2020-11-07T08:17:40Z
false
true
8
GO:0140541
140,541
piRNA transcription
biological_process
The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
[ "PMID:28847004" ]
null
[ "Piwi-associated RNA transcription", "PIWI-interacting RNA transcription" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006351" ]
[]
[]
[]
[ "GO:0006351" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19530\" xsd:anyURI" ]
pg
2020-11-09T16:53:25Z
false
true
2
GO:0140542
140,542
regulation of piRNA transcription
biological_process
Any process that modulates the frequency, rate or extent of the synthesis of a piRNA.
[ "PMID:28847004" ]
null
[]
[]
[]
[]
[]
[ "GO:0006355" ]
[ "regulates GO:0140541" ]
[ "regulates" ]
[ "GO:0140541" ]
[ "GO:0006355", "GO:0140541" ]
[ "GO:0065007", "regulates GO:0140541" ]
[]
[]
[]
[]
[]
pg
2020-11-09T19:08:15Z
false
true
8
GO:0140543
140,543
positive regulation of piRNA transcription
biological_process
Any process that increases the frequency, rate or extent of the synthesis of piRNA.
[ "PMID:28847004" ]
null
[]
[]
[]
[]
[]
[ "GO:0045893", "GO:0140542" ]
[ "positively_regulates GO:0140541" ]
[ "positively_regulates" ]
[ "GO:0140541" ]
[ "GO:0045893", "GO:0140541", "GO:0140542" ]
[ "GO:0065007", "positively_regulates GO:0140541" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19530\" xsd:anyURI" ]
pg
2020-11-09T19:26:02Z
false
true
4
GO:0140544
140,544
septin collar organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar.
[ "PMID:21736496", "PMID:32386534" ]
null
[ "cellular bud neck septin hourglass organization" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032185" ]
[]
[]
[]
[ "GO:0032185" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19534\" xsd:anyURI" ]
pg
2020-11-10T13:47:48Z
false
true
5
GO:0140545
140,545
ATP-dependent protein disaggregase activity
molecular_function
An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.
[ "PMID:26312418" ]
null
[ "protein disaggregase activity", "protein unfoldase activity" ]
[ "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0140657", "GO:0140776" ]
[ "has_part GO:0005515" ]
[ "has_part" ]
[ "GO:0005515" ]
[ "GO:0005515", "GO:0140657", "GO:0140776" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19173\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23065\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23088\" xsd:anyURI" ]
pg
2020-11-10T16:57:19Z
false
true
9
GO:0140546
140,546
defense response to symbiont
biological_process
Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.
[ "GOC:pg" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-9953170 \"GBP-mediated host defense\"" ]
[ "GO:0098542" ]
[]
[]
[]
[ "GO:0098542" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20261\" xsd:anyURI" ]
pg
2020-11-11T17:19:06Z
false
true
4
GO:0140547
140,547
acquisition of seed longevity
biological_process
The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repai...
[ "PMID:26637538" ]
null
[]
[]
[]
[]
[]
[ "GO:0032501" ]
[ "part_of GO:0048316" ]
[ "part_of" ]
[ "GO:0048316" ]
[ "GO:0032501", "GO:0048316" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19829\" xsd:anyURI" ]
pg
2020-11-11T21:28:55Z
false
true
4
GO:0140548
140,548
obsolete venom-mediated platelet agglutination
biological_process
OBSOLETE. A process in which an organism initiates, promotes, or enhances platelet agglutination in another organism via the action of a venom. This may takes place is via specific proteins binding to cell-surface carbohydrates on the platelet's cell membrane, resulting in calcium-dependent agglutination.
[ "PMID:10484740", "PMID:28435120" ]
This term was obsoleted because it represents the same process as venom-mediated platelet aggregation ; GO:0044478.
[ "envenomation resulting in blood agglutination in another organism", "envenomation resulting in blood agglutination in other organism", "venom-mediated blood agglutination" ]
[ "BROAD", "BROAD", "BROAD" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0044478" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18979\" xsd:anyURI" ]
pg
2020-11-11T21:42:31Z
true
true
7
GO:0140549
140,549
spore inner membrane
cellular_component
The membrane surrounding the spore core (endospore core) that separates it from its external environment.
[ "PMID:23202530" ]
null
[ "spore membrane" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0016020" ]
[]
[]
[]
[ "GO:0016020" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20359\" xsd:anyURI" ]
pg
2020-11-12T10:00:15Z
false
true
2
GO:0140550
140,550
phosphatidylinositol-4,5-bisphosphate sensor activity
molecular_function
Binding to and responding, e.g. by conformational change, to changes in the cellular level of phosphatidylinositol-4,5-bisphosphate.
[ "PMID:33172987" ]
null
[ "phosphatidylinositol-4,5-bisphosphate sensing activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0106254" ]
[]
[]
[]
[ "GO:0106254" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20361\" xsd:anyURI" ]
pg
2020-11-12T13:01:17Z
false
true
3
GO:0140552
140,552
TEAD-YAP complex
cellular_component
A transcription factor complex that is composed of the one DNA binding protein of the TEAD family and the transcriptional coactivator YAP.
[ "GOC:mah", "PMID:11358867" ]
null
[ "TEAD-1-YAP complex", "TEAD-2 multiprotein complex", "TEAD-2-YAP complex", "TEAD-3-YAP complex", "TEAD-4-YAP complex" ]
[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]
[ "GO:0071147", "GO:0071148", "GO:0071149", "GO:0071150", "GO:0071151" ]
[]
[ "CORUM:2870" ]
[ "GO:0090575" ]
[]
[]
[]
[ "GO:0090575" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/9300\" xsd:anyURI" ]
pg
2020-11-17T07:05:23Z
false
true
1
GO:0140560
140,560
xylosyl alpha-1,3-xylosyltransferase activity
molecular_function
Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine = UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis...
[ "PMID:22117070", "PMID:8982869", "RHEA:22820" ]
null
[]
[]
[]
[]
[ "EC:2.4.2.62", "RHEA:22820" ]
[ "GO:0035252" ]
[]
[]
[]
[ "GO:0035252" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.2.62", "skos:exactMatch RHEA:22820", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16869\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2020-11-25T13:45:18Z
false
true
8
GO:0140561
140,561
EGF-domain serine glucosyltransferase activity
molecular_function
Catalysis of the reaction: UDP-alpha-D-glucose + [protein with EGF-like domain]-L-serine = UDP + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine.
[ "RHEA:58116" ]
null
[]
[]
[]
[]
[ "EC:2.4.1.376", "RHEA:58116" ]
[ "GO:0035251" ]
[]
[]
[]
[ "GO:0035251" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.1.376", "skos:exactMatch RHEA:58116", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16869\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2020-11-25T14:19:23Z
false
true
1
GO:0140562
140,562
EGF-domain serine xylosyltransferase activity
molecular_function
Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine = UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine.
[ "RHEA:62016" ]
null
[]
[]
[]
[]
[ "EC:2.4.2.63", "RHEA:62016" ]
[ "GO:0035252" ]
[]
[]
[]
[ "GO:0035252" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.2.63", "skos:exactMatch RHEA:62016", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16869\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2020-11-25T14:30:56Z
false
true
1
GO:0140563
140,563
UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity
molecular_function
Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine = UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.
[ "EC:2.4.2.42", "PMID:30127001", "RHEA:56064" ]
null
[]
[]
[]
[]
[ "EC:2.4.2.42", "RHEA:56064" ]
[ "GO:0035252" ]
[]
[]
[]
[ "GO:0035252" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.2.42", "skos:exactMatch RHEA:56064", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16869\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2020-11-25T16:07:58Z
false
true
6
GO:0140566
140,566
histone reader activity
molecular_function
A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the tra...
[ "PMID:11498575", "PMID:25688442", "PMID:31082667", "PMID:34726351" ]
null
[ "epigenetic reader", "histone reader" ]
[ "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0140463" ]
[ "has_part GO:0042393", "occurs_in GO:0000786" ]
[ "has_part", "occurs_in" ]
[ "GO:0042393", "GO:0000786" ]
[ "GO:0000786", "GO:0042393", "GO:0140463" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20551\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22136\" xsd:anyURI" ]
pg
2020-12-11T13:25:49Z
false
true
6
GO:0140567
140,567
membrane protein dislocase activity
molecular_function
The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. The reaction is driven by ATP hydrolysis.
[ "PMID:24821790", "PMID:28712723", "PMID:32973005" ]
null
[ "transmembrane helix dislocase", "transmembrane protein dislocase activity" ]
[ "RELATED", "RELATED" ]
[]
[]
[ "RHEA:66168" ]
[ "GO:0140597", "GO:0140657" ]
[]
[]
[]
[ "GO:0140597", "GO:0140657" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch RHEA:66168", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20237\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22209\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30369\" xsd:anyURI" ]
pg
2020-12-15T07:13:21Z
false
true
5
GO:0140568
140,568
extraction of mislocalized protein from membrane
biological_process
The removal of a mislocalized protein from a cellular membrane.
[ "PMID:24821790", "PMID:28712723", "PMID:32973005" ]
null
[]
[]
[]
[]
[]
[ "GO:0090150" ]
[]
[]
[]
[ "GO:0090150" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20237\" xsd:anyURI" ]
pg
2020-12-15T07:35:10Z
false
true
7
GO:0140569
140,569
extraction of mislocalized protein from ER membrane
biological_process
The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane.
[ "PMID:32973005" ]
null
[]
[]
[]
[]
[]
[ "GO:0140568" ]
[]
[]
[]
[ "GO:0140568" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20237\" xsd:anyURI" ]
pg
2020-12-15T07:36:46Z
false
true
4
GO:0140571
140,571
transmembrane ascorbate ferrireductase activity
molecular_function
Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.
[ "PMID:16911521", "PMID:24449903", "RHEA:30403" ]
null
[ "ascorbate-cytochrome b5 reductase activity", "L-ascorbate-cytochrome-b5 reductase activity", "L-ascorbate:ferricytochrome-b5 oxidoreductase activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "EC:7.2.1.3", "MetaCyc:RXN-15598", "RHEA:30403" ]
[ "GO:0015453", "GO:0016722" ]
[]
[]
[]
[ "GO:0015453", "GO:0016722" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:7.2.1.3", "skos:exactMatch RHEA:30403", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26941\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2020-12-18T16:25:06Z
false
true
7
GO:0140572
140,572
vacuole fission
biological_process
The division of a vacuole within a cell to form two or more separate vacuoles.
[ "PMID:19643199" ]
null
[]
[]
[]
[]
[]
[ "GO:0048285" ]
[]
[]
[]
[ "GO:0048285" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20639\" xsd:anyURI" ]
pg
2021-01-04T10:17:58Z
false
true
3
GO:0140573
140,573
histone H3-containing nucleosome
cellular_component
A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures.
[ "PMID:33155135" ]
null
[ "histone H3 containing nucleosome" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000786" ]
[]
[]
[]
[ "GO:0000786" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20585\" xsd:anyURI" ]
pg
2021-01-04T16:22:43Z
false
true
7
GO:0140575
140,575
transmembrane monodehydroascorbate reductase activity
molecular_function
Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.
[ "PMID:1623014", "RHEA:66524" ]
null
[]
[]
[]
[]
[ "RHEA:66524" ]
[ "GO:0016491" ]
[]
[]
[]
[ "GO:0016491" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:66524", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20602\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2021-01-07T16:20:04Z
false
true
5
GO:0140576
140,576
ascorbate homeostasis
biological_process
Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell.
[ "PMID:1623014", "PMID:17068337", "PMID:32547589" ]
null
[ "cellular ascorbate homeostasis" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0033500" ]
[]
[]
[]
[ "GO:0033500" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20602\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20672\" xsd:anyURI" ]
pg
2021-01-07T16:50:44Z
false
true
4
GO:0140579
140,579
obsolete oxidoreductase activity, reducing metal ions
molecular_function
OBSOLETE. Catalysis of an oxidation-reduction in which the metal ion is reduced.
[ "PMID:14499595" ]
This term was obsoleted because it is an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0016722" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20675\" xsd:anyURI" ]
pg
2021-01-13T06:55:01Z
true
true
6
GO:0140582
140,582
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
biological_process
An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by extracellular cAMP binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.
[ "PMID:9578623" ]
null
[ "extracellular cAMP signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007189" ]
[]
[]
[]
[ "GO:0007189" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20487\" xsd:anyURI" ]
pg
2021-01-18T19:30:30Z
false
true
1
GO:0140584
140,584
chromatin extrusion motor activity
molecular_function
A DNA translocase activity that folds chromosomal DNA and catalytically extends the newly formed loop, driven by ATP hydrolysis.
[ "PMID:23074191", "PMID:26499245", "PMID:27210764" ]
null
[ "chromatin extrusion activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0015616" ]
[ "part_of GO:0140588" ]
[ "part_of" ]
[ "GO:0140588" ]
[ "GO:0015616", "GO:0140588" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:13065", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20204\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21647\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2021-02-01T13:42:08Z
false
true
7
GO:0140585
140,585
promoter-enhancer loop anchoring activity
molecular_function
Bridging together two cis-regulatory elements, colloquially referred to as promoters and/or enhancers, holding two loop anchors together to maintain a chromatin loop.
[ "PMID:32213323" ]
Note that GO does not separately defines enhancers, since this concept is very close to that of cis-regulatory elements. However the literature refers to 'promoter-enhancer loops' to describe loops that bring together cis-regulatory elements. Note also that while SO defines 'promoter' as the core promoter, here it is u...
[ "enhancer-promoter loop anchoring activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140587" ]
[]
[]
[]
[ "GO:0140587" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20204\" xsd:anyURI" ]
pg
2021-02-04T14:50:04Z
false
true
9
GO:0140586
140,586
promoter-terminator loop anchoring activity
molecular_function
Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop.
[ "PMID:19933151" ]
Note that GO does not separately defines enhancers, since this concept is very close to that of cis-regulatory elements. However the literature refers to 'promoter-enhancer loops' to describe loops that bring together cis-regulatory elements. Note also that while SO defines 'promoter' as the core promoter, here it is u...
[ "terminator-promoter loop anchoring activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140587" ]
[]
[]
[]
[ "GO:0140587" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20204\" xsd:anyURI" ]
pg
2021-02-04T14:51:44Z
false
true
6