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GO

Dataset card Data Studio Files
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 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0140717
140,717
entry into host through the stromata
biological_process
Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.
[ "PMID:16959560", "PMID:17419713", "PMID:29307013" ]
null
[]
[]
[]
[]
[]
[ "GO:0044409" ]
[]
[]
[]
[ "GO:0044409" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22206\" xsd:anyURI" ]
pg
2021-09-27T16:30:08Z
false
true
4
GO:0140718
140,718
facultative heterochromatin formation
biological_process
The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the ...
[ "PMID:17936700" ]
Note that facultative heterochromatin can be reprogrammed, as opposed to constitutive heterochromatin which usually cannot be reprogrammed to a transcriptionally-competent state. Note also that facultative heterochromatin formation does not usually involve DNA methylation, while constitutive heterochromatin formation d...
[ "facultative heterochromatin assembly", "fHC assembly" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0031507" ]
[]
[]
[]
[ "GO:0031507" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22325\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23553\" xsd:anyURI" ]
pg
2021-10-29T13:40:47Z
false
true
1
GO:0140719
140,719
constitutive heterochromatin formation
biological_process
The compaction of chromatin into heterochromatin, a conformation that is refractory to transcription and in that involves the methylation of histone H3K9. Constitutive heterochromatin cannot be converted back to euchromatin, the transcriptionally-active conformation.
[ "PMID:17936700" ]
Note that constitutive heterochromatin usually cannot be reprogrammed to a transcriptionally-competent state, as opposed to facultative heterochromatin, which can be reprogrammed. Note also that constitutive usually involves DNA methylation, while facultative heterochromatin formation does not.
[ "constitutive heterochromatin assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0031507" ]
[]
[]
[]
[ "GO:0031507" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22325\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23553\" xsd:anyURI" ]
pg
2021-10-29T13:41:09Z
false
true
1
GO:0140720
140,720
subtelomeric heterochromatin
cellular_component
Heterochromatin that is located adjacent to the telomere, and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).
[ "PMID:34576871" ]
null
[]
[]
[]
[]
[]
[ "GO:0000792" ]
[ "part_of GO:0099115" ]
[ "part_of" ]
[ "GO:0099115" ]
[ "GO:0000792", "GO:0099115" ]
[ "GO:0000792", "part_of GO:0099115" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22353\" xsd:anyURI" ]
pg
2021-11-05T13:19:40Z
false
true
8
GO:0140721
140,721
nuclease inhibitor activity
molecular_function
Binds to and modulates the activity of a nuclease.
[ "PMID:28785032", "PMID:29554913", "PMID:30046034" ]
null
[]
[]
[]
[]
[]
[ "GO:0004857" ]
[ "negatively_regulates GO:0004518" ]
[ "negatively_regulates" ]
[ "GO:0004518" ]
[ "GO:0004518", "GO:0004857" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16423\" xsd:anyURI" ]
pg
2021-11-16T09:09:45Z
false
true
5
GO:0140722
140,722
mycophenolic acid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of mycophenolic acid (MPA). MPA is the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893.
[ "PMID:21398490", "PMID:26751579", "PMID:31209052" ]
null
[ "MPA anabolism", "MPA biosynthesis", "MPA formation", "MPA synthesis", "mycophenolic acid anabolism", "mycophenolic acid biosynthesis", "mycophenolic acid formation", "mycophenolic acid synthesis" ]
[ "BROAD", "BROAD", "BROAD", "BROAD", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0017000", "GO:0030639", "GO:0043386", "GO:0046189", "GO:0072330", "GO:1901336" ]
[]
[]
[]
[ "GO:0017000", "GO:0030639", "GO:0043386", "GO:0046189", "GO:0072330", "GO:1901336" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22374\" xsd:anyURI" ]
pg
2021-11-18T06:12:47Z
false
true
8
GO:0140723
140,723
patulin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria.
[ "PMID:25120234", "PMID:30680886" ]
null
[ "patulin anabolism", "patulin biosynthesis", "patulin formation", "patulin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030639", "GO:0043386", "GO:0046165", "GO:1901336" ]
[]
[]
[]
[ "GO:0030639", "GO:0043386", "GO:0046165", "GO:1901336" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22373\" xsd:anyURI" ]
pg
2021-11-18T06:25:59Z
false
true
7
GO:0140724
140,724
positive regulation of patulin biosynthetic process
biological_process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of patulin.
[ "PMID:25625822" ]
null
[ "positive regulation of patulin anabolism", "positive regulation of patulin formation", "positive regulation of patulin synthesis" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1900734", "GO:1902932" ]
[ "positively_regulates GO:0140723" ]
[ "positively_regulates" ]
[ "GO:0140723" ]
[ "GO:0140723", "GO:1900734", "GO:1902932" ]
[ "GO:0065007", "positively_regulates GO:0140723" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22373\" xsd:anyURI" ]
pg
2021-11-18T06:32:18Z
false
true
8
GO:0140725
140,725
detoxification of free heme
biological_process
Any process that reduces or removes the toxicity of free heme. These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme.
[ "PMID:26741528", "PMID:32983129" ]
null
[ "free heme detoxification" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0098754" ]
[]
[]
[]
[ "GO:0098754" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21264\" xsd:anyURI" ]
pg
2021-11-18T09:03:32Z
false
true
4
GO:0140727
140,727
siRNA-mediated pericentric heterochromatin formation
biological_process
The formation of pericentric heterochromatin by a process mediated by a small interfering RNA (siRNA).
[ "PMID:15289661" ]
null
[ "RNAi-mediated heterochromatin assembly at centromere", "siRNA dependent pericentric heterochromatin assembly", "siRNA-dependent pericentric heterochromatin assembly", "siRNA-dependent pericentric heterochromatin formation" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0031508", "GO:0141194" ]
[]
[]
[]
[ "GO:0031508", "GO:0141194" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22365\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23553\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23751\" xsd:anyURI", "term_tracker_item \"https://gi...
pg
2021-11-22T08:02:22Z
false
true
3
GO:0140728
140,728
GC-box binding
molecular_function
Binding to a GC-box, a DNA motif with the consensus sequence GGGCGG that is located upstream of the start point of eukaryotic transcription units. The GC-box may occur in multiple copies or in either orientation relative to the transcription start site.
[ "PMID:14701757" ]
null
[ "GC box binding", "GC rich promoter region binding", "GC-rich region binding", "GC_rich_promoter_region binding" ]
[ "EXACT", "BROAD", "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0000978" ]
[]
[]
[]
[ "GO:0000978" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22414\" xsd:anyURI" ]
pg
2021-11-23T08:51:58Z
false
true
5
GO:0140729
140,729
detoxification of endogenously produced metabolite
biological_process
A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme.
[ "PMID:21923907", "PMID:29763292" ]
null
[ "prevention of self-toxicity", "self-resistance to bioactive secondary metabolite", "self-resistance to endogenously produced compound", "self-resistance to endogenously produced metabolite", "self-resistance to endogenously produced toxin" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0098754" ]
[]
[]
[]
[ "GO:0098754" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22413\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31336\" xsd:anyURI" ]
pg
2021-11-24T06:32:14Z
false
true
9
GO:0140730
140,730
amphiregulin production
biological_process
The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a...
[ "PMID:24463227" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "AREG production" ]
[ "BROAD" ]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0001816" ]
[]
[]
[]
[ "GO:0001816" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21878\" xsd:anyURI" ]
pg
2021-11-24T07:09:44Z
false
true
4
GO:0140731
140,731
regulation of amphiregulin production
biological_process
Any process that modulates the frequency, rate, or extent of production of amphiregulin.
[ "PMID:24463227" ]
null
[ "regulation of AREG production" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0001817" ]
[ "regulates GO:0140730" ]
[ "regulates" ]
[ "GO:0140730" ]
[ "GO:0001817", "GO:0140730" ]
[ "GO:0065007", "regulates GO:0140730" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21878\" xsd:anyURI" ]
pg
2021-11-24T07:10:04Z
false
true
6
GO:0140732
140,732
positive regulation of amphiregulin production
biological_process
Any process that activates or increases the frequency, rate or extent of production of amphiregulin.
[ "PMID:24463227" ]
null
[ "positive regulation of AREG production" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0001819", "GO:0140731" ]
[ "positively_regulates GO:0140730" ]
[ "positively_regulates" ]
[ "GO:0140730" ]
[ "GO:0001819", "GO:0140730", "GO:0140731" ]
[ "GO:0065007", "positively_regulates GO:0140730" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21878\" xsd:anyURI" ]
pg
2021-11-24T07:20:02Z
false
true
1
GO:0140733
140,733
tRNA ligase activator activity
molecular_function
Binds to and increases the activity of a tRNA ligase.
[ "PMID:30943413" ]
null
[]
[]
[]
[]
[]
[ "GO:0008047", "GO:0055103" ]
[ "positively_regulates GO:0004812" ]
[ "positively_regulates" ]
[ "GO:0004812" ]
[ "GO:0004812", "GO:0008047", "GO:0055103" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22153\" xsd:anyURI" ]
pg
2021-11-24T09:10:19Z
false
true
9
GO:0140734
140,734
ammonium excretion
biological_process
The elimination of ammonium ions from an excretory cell.
[ "PMID:25740900" ]
null
[ "ammonia excretion" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0007588" ]
[]
[]
[]
[ "GO:0007588" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22368\" xsd:anyURI" ]
pg
2021-11-24T17:55:51Z
false
true
1
GO:0140735
140,735
lovastatin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR).
[ "PMID:10334994", "PMID:10381407" ]
null
[ "lovastatin anabolism", "lovastatin biosynthesis", "lovastatin formation", "lovastatin synthesis", "mevacor anabolism", "mevacor biosynthesis", "mevacor biosynthetic process", "mevacor formation", "mevacor synthesis", "mevinolin anabolism", "mevinolin biosynthesis", "mevinolin biosynthetic pro...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "kegg.module:M00893", "MetaCyc:PWY-7535" ]
[ "GO:0030639", "GO:0043386", "GO:1901336", "GO:1901570" ]
[]
[]
[]
[ "GO:0030639", "GO:0043386", "GO:1901336", "GO:1901570" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22454\" xsd:anyURI" ]
pg
2021-11-26T12:23:06Z
false
true
2
GO:0140736
140,736
positive regulation of lovastatin biosynthetic process
biological_process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of lovastin.
[ "PMID:10334994", "PMID:19781329" ]
null
[ "positive regulation of mevacor biosynthetic process", "positive regulation of mevinolin biosynthetic process", "positive regulation of monacolin K biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046889", "GO:1900734" ]
[ "positively_regulates GO:0140735" ]
[ "positively_regulates" ]
[ "GO:0140735" ]
[ "GO:0046889", "GO:0140735", "GO:1900734" ]
[ "GO:0065007", "positively_regulates GO:0140735" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22454\" xsd:anyURI" ]
pg
2021-11-26T12:33:56Z
false
true
9
GO:0140737
140,737
encapsulin nanocompartment
cellular_component
Intracellular non-membrane bound organelle, consisting of proteinaceous polyhedral shells that encapsulate enzymes, protecting the contents from their surrounding milieu and/or the milieu from reactants in their interior. The self-assembling, 25-42 nm nanocompartment shell, unlike larger bacterial microcompartments, is...
[ "PMID:32918485" ]
null
[ "protein nanocompartment" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0043232" ]
[]
[]
[]
[ "GO:0043232" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22465\" xsd:anyURI" ]
pg
2021-11-29T09:16:25Z
false
true
3
GO:0140738
140,738
NLRP6 inflammasome complex
cellular_component
An inflammasome complex that consists of NLRP6, PYCARD/ASC and caspase-1 or caspase-4/caspase-11.
[ "PMID:30674671", "PMID:34678144" ]
null
[]
[]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22481\" xsd:anyURI" ]
pg
2021-11-30T06:12:14Z
false
true
3
GO:0140740
140,740
ADP-riboxanase activity
molecular_function
Catalysis of the reaction: L-arginyl-[protein] + NAD+ = ADP-riboxanated L-argininyl-[protein] + H+ + NH4+ + nicotinamide.
[ "PMID:34671164", "RHEA:69500" ]
Note that this activity has two steps: a transfer of an ADP-ribose group, followed by the elimination of an ammonia group.
[]
[]
[]
[]
[ "Reactome:R-HSA-9956624 \"OspC3 ADP-riboxanates CASP4\"", "RHEA:69500", "RHEA:75883", "RHEA:75887" ]
[ "GO:0016772", "GO:0016841", "GO:0140096" ]
[]
[]
[]
[ "GO:0016772", "GO:0016841", "GO:0140096" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:69500", "skos:narrowMatch RHEA:75883", "skos:narrowMatch RHEA:75887", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22480\" xsd:anyURI" ]
pg
2021-11-30T08:29:49Z
false
true
6
GO:0140742
140,742
lncRNA transcription
biological_process
The transcription of lncRNAs, non-coding RNAs over 200 nucleotides in length, from a DNA template.
[ "PMID:33767452", "PMID:33913806" ]
null
[]
[]
[]
[]
[]
[ "GO:0006351" ]
[]
[]
[]
[ "GO:0006351" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22534\" xsd:anyURI" ]
pg
2021-12-09T08:40:49Z
false
true
5
GO:0140743
140,743
regulation of lncRNA transcription
biological_process
Any process that modulates the frequency, rate or extent of the synthesis of a lncRNA.
[ "PMID:33767452", "PMID:33913806" ]
null
[]
[]
[]
[]
[]
[ "GO:0006355" ]
[ "regulates GO:0140742" ]
[ "regulates" ]
[ "GO:0140742" ]
[ "GO:0006355", "GO:0140742" ]
[ "GO:0065007", "regulates GO:0140742" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22534\" xsd:anyURI" ]
pg
2021-12-09T08:47:54Z
false
true
8
GO:0140744
140,744
negative regulation of lncRNA transcription
biological_process
Any process that decreases the frequency, rate or extent of the synthesis of a lncRNA.
[ "PMID:33767452", "PMID:33913806" ]
null
[]
[]
[]
[]
[]
[ "GO:0045892", "GO:0140743" ]
[ "negatively_regulates GO:0140742" ]
[ "negatively_regulates" ]
[ "GO:0140742" ]
[ "GO:0045892", "GO:0140742", "GO:0140743" ]
[ "GO:0065007", "negatively_regulates GO:0140742" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22534\" xsd:anyURI" ]
pg
2021-12-09T08:49:57Z
false
true
7
GO:0140745
140,745
siRNA transcription
biological_process
The transcription of a small interfering RNA from an RNA template.
[ "PMID:23001036" ]
null
[]
[]
[]
[]
[]
[ "GO:0001172" ]
[]
[]
[]
[ "GO:0001172" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19303\" xsd:anyURI" ]
pg
2021-12-13T13:08:09Z
false
true
2
GO:0140746
140,746
siRNA catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of small interfering RNA transcripts (siRNAs).
[ "PMID:25928405" ]
null
[]
[]
[]
[]
[]
[ "GO:0006401" ]
[]
[]
[]
[ "GO:0006401" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19303\" xsd:anyURI" ]
pg
2021-12-13T13:11:22Z
false
true
5
GO:0140747
140,747
obsolete regulation of ncRNA transcription
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of a non-protein coding gene from a DNA-template.
[ "GOC:pg" ]
The reason for obsoletion is that this term was added in error.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
pg
2021-12-13T14:14:09Z
true
true
8
GO:0140749
140,749
phlorizin hydrolase activity
molecular_function
Catalysis of the reaction: phlorizin + H2O = beta-D-glucose + phloretin.
[ "PMID:9762914", "RHEA:69639" ]
null
[]
[]
[]
[]
[ "RHEA:69639" ]
[ "GO:0004553" ]
[]
[]
[]
[ "GO:0004553" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:69639", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22611\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28324\" xsd:anyURI" ]
pg
2022-01-11T08:45:32Z
false
true
7
GO:0140750
140,750
nucleosome array spacer activity
molecular_function
A histone octamer slider activity that spaces nucleosomes along chromosomal DNA. This activity is involved in assembling chromatin in uniform nucleosome arrays to regulate transcription by RNA polymerases I, II, and III, as well as DNA replication, recombination and repair.
[ "PMID:11683384", "PMID:16468993" ]
In Drosphila, this is mediated by ISWI, in human, by SMARCA5 and in S. cerevisiae by ISW1 and and ISW2.
[ "nucleosome array spacing activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140751" ]
[]
[]
[]
[ "GO:0140751" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22115\" xsd:anyURI" ]
pg
2022-01-14T13:25:34Z
false
true
7
GO:0140751
140,751
histone octamer slider activity
molecular_function
A chromatin remodeler activity that slides core histone octamers along chromosomal DNA.
[ "PMID:10466730" ]
This activity is mediated by at least three subfamilies of the SNF2 remodellers, namely the bromodomain domain, the chromodomain containing and the imitation switch subfamilies.
[ "histone octamer sliding activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140658" ]
[]
[]
[]
[ "GO:0140658" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22115\" xsd:anyURI" ]
pg
2022-01-14T14:53:02Z
false
true
7
GO:0140752
140,752
branched 1,3-beta-D-glucan synthase activity
molecular_function
Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + a branched [(1->3)-beta-D-glucosyl](n+1).
[ "PMID:34959732" ]
null
[]
[]
[]
[]
[]
[ "GO:0003843" ]
[]
[]
[]
[ "GO:0003843" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22637\" xsd:anyURI" ]
pg
2022-01-18T09:47:40Z
false
true
8
GO:0140753
140,753
linear 1,3-beta-D-glucan synthase activity
molecular_function
Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + a linear [(1->3)-beta-D-glucosyl](n+1).
[ "PMID:34959732" ]
null
[]
[]
[]
[]
[]
[ "GO:0003843" ]
[]
[]
[]
[ "GO:0003843" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22637\" xsd:anyURI" ]
pg
2022-01-18T09:47:51Z
false
true
5
GO:0140754
140,754
reorganization of cellular membranes to establish viral sites of replication
biological_process
A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.
[ "PMID:19376974" ]
null
[]
[]
[]
[]
[]
[ "GO:0141171" ]
[]
[]
[]
[ "GO:0141171" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22686\" xsd:anyURI" ]
pg
2022-01-18T14:25:00Z
false
true
3
GO:0140755
140,755
reorganization of host cellular membranes to establish sites of replication
biological_process
A process in which a virus triggers host intracellular membranes to be reorganized, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.
[ "PMID:34699787", "PMID:4372566" ]
null
[]
[]
[]
[]
[]
[ "GO:0016032", "GO:0141171" ]
[]
[]
[]
[ "GO:0016032", "GO:0141171" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22686\" xsd:anyURI" ]
pg
2022-01-18T17:02:36Z
false
true
7
GO:0140756
140,756
structural constituent of proteasome
molecular_function
The action of a molecule that contributes to the structural integrity of the proteasome.
[ "PMID:10500111", "PMID:28525752", "PMID:28583440", "PMID:29652515" ]
null
[]
[]
[]
[]
[]
[ "GO:0005198" ]
[ "occurs_in GO:0000502" ]
[ "occurs_in" ]
[ "GO:0000502" ]
[ "GO:0000502", "GO:0005198" ]
[ "GO:0005198", "occurs_in GO:0000502" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22694\" xsd:anyURI" ]
pg
2022-01-19T08:45:12Z
false
true
4
GO:0140757
140,757
cysteine-type deNEDDylase activity
molecular_function
An thiol-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.
[ "PMID:25628956" ]
null
[]
[]
[]
[]
[]
[ "GO:0008234", "GO:0019784" ]
[]
[]
[]
[ "GO:0008234", "GO:0019784" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19573\" xsd:anyURI" ]
pg
2022-01-24T12:33:36Z
false
true
5
GO:0140758
140,758
metal-dependent deNEDDylase activity
molecular_function
An metal-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.
[ "PMID:25628956" ]
null
[]
[]
[]
[]
[]
[ "GO:0008237", "GO:0019784" ]
[]
[]
[]
[ "GO:0008237", "GO:0019784" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19573\" xsd:anyURI" ]
pg
2022-01-24T12:45:57Z
false
true
8
GO:0140759
140,759
histone H3K56 methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 56) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 56). This reaction is the addition of a methyl group to the lysine residue at position 56 of the histone H3 protein.
[ "PMID:23451023", "PMID:28743002", "RHEA:85519" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "histone H3K56 methylase activity", "histone lysine N-methyltransferase activity (H3-K56 specific)", "histone methyltransferase activity (H3-K56 specific)", "histone-H3K56 methyltransferase activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "RHEA:85519" ]
[ "GO:0016279", "GO:0140938" ]
[]
[]
[]
[ "GO:0016279", "GO:0140938" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:85519", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22757\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24337\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", ...
pg
2022-01-28T08:39:20Z
false
true
2
GO:0140760
140,760
histone H3K56me2/H3K56me3 demethylase activity
molecular_function
Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 56 of the histone H3 protein.
[ "PMID:23451023", "PMID:28743002" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "histone demethylase activity (H3-K56 specific)", "histone H3-tri/dimethyl-lysine-56 demethylase activity", "histone H3K56me2 demethylase activity", "histone H3K56me3 demethylase activity" ]
[ "RELATED", "EXACT", "RELATED", "RELATED" ]
[]
[]
[ "RHEA:85927", "RHEA:85931" ]
[ "GO:0016706", "GO:0141052" ]
[]
[]
[]
[ "GO:0016706", "GO:0141052" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch RHEA:85927", "skos:narrowMatch RHEA:85931", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22757\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29636\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-onto...
pg
2022-01-28T08:45:09Z
false
true
1
GO:0140761
140,761
calmodulin-activated 3',5'-cyclic-AMP phosphodiesterase activity
molecular_function
Catalysis of the reactions: nucleoside 3',5'-cyclic AMP + H2O = AMP + H+; this activity is activated by binding to calcium-bound calmodulin.
[ "PMID:15901640" ]
null
[ "calcium- and calmodulin-regulated 3',5'-cyclic-AMP phosphodiesterase activity", "calcium- and calmodulin-regulated AMP-specific phosphodiesterase activity", "calcium- and calmodulin-regulated cAMP phosphodiesterase activity", "calcium- and calmodulin-regulated cyclic-AMP phosphodiesterase activity", "calci...
[ "BROAD", "EXACT", "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004115" ]
[]
[]
[]
[ "GO:0004115" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22791\" xsd:anyURI" ]
pg
2022-02-02T09:34:34Z
false
true
2
GO:0140762
140,762
glucose dehydrogenase (FAD, quinone) activity
molecular_function
Catalysis of the reaction: a quinone + D-glucose = a quinol + D-glucono-1,5-lactone.
[ "RHEA:47372" ]
null
[]
[]
[]
[]
[ "EC:1.1.5.9", "MetaCyc:GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN", "RHEA:47372" ]
[ "GO:0004344", "GO:0016901" ]
[]
[]
[]
[ "GO:0004344", "GO:0016901" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.1.5.9", "skos:exactMatch RHEA:47372", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22585\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25441\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontolo...
pg
2022-02-04T08:02:40Z
false
true
5
GO:0140763
140,763
programmed DNA elimination by elimination of internal DNA segments
biological_process
A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates.
[ "PMID:18708581" ]
null
[]
[]
[]
[]
[]
[ "GO:0031049" ]
[]
[]
[]
[ "GO:0031049" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22815\" xsd:anyURI" ]
pg
2022-02-07T09:49:18Z
false
true
7
GO:0140764
140,764
small RNA binding translational repressor activity
molecular_function
A translational repressor activity that binds to a single-stranded small regulatory RNA (either a miRNA or a siRNA) to guide it to its target mRNA.
[ "PMID:27184117", "PMID:34117606" ]
This term is intended for activities such as that mediated by argonaute in the RISC complex, that bring a miRNA or an siRNA to their target mRNA.
[]
[]
[]
[]
[]
[ "GO:0030371" ]
[ "has_part GO:0061980", "part_of GO:0016441" ]
[ "has_part", "part_of" ]
[ "GO:0061980", "GO:0016441" ]
[ "GO:0016441", "GO:0030371", "GO:0061980" ]
[ "GO:0030371", "has_part GO:0061980", "part_of GO:0016441" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22780\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23021\" xsd:anyURI" ]
pg
2022-02-07T13:26:07Z
false
true
4
GO:0140765
140,765
histone H3K56 deacetylase activity, NAD-dependent
molecular_function
Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 56) + NAD+ + H2O = histone H3 L-lysine (position 56) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K56 to NAD, producing nicotinamide.
[ "PMID:23911928", "PMID:30374165" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "NAD-dependent histone deacetylase activity (H3-K56 specific)", "NAD-dependent histone H3-K56 deacetylase activity", "NAD-dependent histone H3K56 deacetylase activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0017136", "GO:0141050" ]
[]
[]
[]
[ "GO:0017136", "GO:0141050" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.3.1.286", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22829\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22836\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ...
pg
2022-02-09T08:00:41Z
false
true
8
GO:0140766
140,766
siRNA-mediated post-transcriptional gene silencing
biological_process
A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into...
[ "PMID:26372022" ]
null
[ "gene silencing by siRNA", "post-transcriptional gene silencing by siRNA", "posttranscriptional gene silencing by siRNA", "siRNA-mediated gene silencing", "siRNA-mediated PTGS" ]
[ "EXACT", "EXACT", "EXACT", "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0035194" ]
[]
[]
[]
[ "GO:0035194" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22860\" xsd:anyURI" ]
pg
2022-02-14T14:01:39Z
false
true
6
GO:0140767
140,767
enzyme-substrate adaptor activity
molecular_function
An adaptor that brings together an enzyme and its substrate. Adaptors recruit the substrate to its enzyme, thus contributing to substrate selection and specificity.
[ "PMID:16250895", "PMID:34358446" ]
null
[ "protein substrate chaperone activity", "protein-substrate adaptor activity" ]
[ "RELATED", "BROAD" ]
[]
[]
[ "Reactome:R-HSA-202137 \"AKT1 binds eNOS complex via HSP90\"", "Reactome:R-HSA-5653886 \"B4GALT1 binds LALBA\"" ]
[ "GO:0030674" ]
[]
[]
[]
[ "GO:0030674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22972\" xsd:anyURI" ]
pg
2022-03-02T08:42:23Z
false
true
8
GO:0140768
140,768
protein ADP-ribosyltransferase-substrate adaptor activity
molecular_function
An enzyme-substrate adaptor that bings together a protein ADP-ribosyl transferase and its substrate.
[ "PMID:32028527" ]
null
[]
[]
[]
[]
[]
[ "GO:0140767" ]
[]
[]
[]
[ "GO:0140767" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI" ]
pg
2022-03-02T08:54:30Z
false
true
6
GO:0140769
140,769
ACP-dependent peptidyl-lysine N6-myristoyltransferase activity
molecular_function
Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-[ACP] = H+ + holo-[ACP] + N(6)-tetradecanoyl-L-lysyl-[protein].
[ "PMID:32461253", "RHEA:70611" ]
null
[]
[]
[]
[]
[ "RHEA:70611" ]
[ "GO:0018030" ]
[]
[]
[]
[ "GO:0018030" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:70611", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22968\" xsd:anyURI" ]
pg
2022-03-02T12:44:18Z
false
true
2
GO:0140770
140,770
CoA-dependent peptidyl-lysine N6-myristoyltransferase activity
molecular_function
Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H+ + N(6)-tetradecanoyl-L-lysyl-[protein].
[ "PMID:1402651", "RHEA:59752" ]
null
[]
[]
[]
[]
[ "RHEA:59752", "RHEA:70671" ]
[ "GO:0018030" ]
[]
[]
[]
[ "GO:0018030" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:59752", "skos:narrowMatch RHEA:70671", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22968\" xsd:anyURI" ]
pg
2022-03-02T12:45:16Z
false
true
5
GO:0140771
140,771
ACP-dependent peptidyl-lysine N6-palmitoyltransferase activity
molecular_function
Catalysis of the reaction: hexadecanoyl-[ACP] + L-lysyl-[protein] = H+ + holo-[ACP] + N(6)-hexadecanoyl-L-lysyl-[protein].
[ "PMID:32461253", "RHEA:70615" ]
null
[]
[]
[]
[]
[ "RHEA:70615" ]
[ "GO:0018031" ]
[]
[]
[]
[ "GO:0018031" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:70615", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22968\" xsd:anyURI" ]
pg
2022-03-02T12:51:53Z
false
true
5
GO:0140772
140,772
CoA-dependent peptidyl-lysine N6-palmitoyltransferase activity
molecular_function
Catalysis of the reaction: L-lysyl-[protein] + hexadecanoyl-CoA = CoA + H+ + N(6)-hexadecanoyl-L-lysyl-[protein].
[ "PMID:30061757" ]
null
[]
[]
[]
[]
[ "RHEA:59768" ]
[ "GO:0018031" ]
[]
[]
[]
[ "GO:0018031" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch RHEA:59768", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22968\" xsd:anyURI" ]
pg
2022-03-02T12:52:22Z
false
true
4
GO:0140773
140,773
NAD-dependent protein demyristoylase activity
molecular_function
Catalysis of the reaction: N6-tetradecanoyl-L-lysyl-[protein] + NAD+ + H2O = tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
[ "PMID:23552949", "RHEA:70567" ]
null
[]
[]
[]
[]
[ "RHEA:70567" ]
[ "GO:0016747" ]
[ "part_of GO:0043687" ]
[ "part_of" ]
[ "GO:0043687" ]
[ "GO:0016747", "GO:0043687" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:70567", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22875\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-03-02T15:21:37Z
false
true
9
GO:0140775
140,775
actin filament debranching activity
molecular_function
Binding to an actin filament and promoting the dissociation of an actin filament branch.
[ "PMID:20362448" ]
null
[ "actin debranching activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140776" ]
[ "has_part GO:0051015", "part_of GO:0030036" ]
[ "has_part", "part_of" ]
[ "GO:0051015", "GO:0030036" ]
[ "GO:0030036", "GO:0051015", "GO:0140776" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18437\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23065\" xsd:anyURI" ]
pg
2022-03-23T07:37:53Z
false
true
8
GO:0140777
140,777
protein-containing complex stabilizing activity
molecular_function
A molecular function that involves direct binding to one of the subunits of a protein-containing complex, thus preventing an interaction with a factor that would promote dissociation of the complex.
[ "PMID:34040253" ]
null
[]
[]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23065\" xsd:anyURI" ]
pg
2022-03-23T12:57:00Z
false
true
3
GO:0140778
140,778
microtubule stabilizing activity
molecular_function
A protein-containing complex stabilizing activity that prevents dissociation of microtubules.
[ "PMID:34970964" ]
null
[]
[]
[]
[]
[]
[ "GO:0140777" ]
[]
[]
[]
[ "GO:0140777" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23014\" xsd:anyURI" ]
pg
2022-03-23T13:20:26Z
false
true
1
GO:0140779
140,779
XCL1 production
biological_process
The appearance of XCL1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "PMID:7973732" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "lymphotactin production" ]
[ "EXACT" ]
[]
[ "gocheck_do_not_annotate" ]
[ "Wikipedia:XCL1" ]
[ "GO:0001816" ]
[]
[]
[]
[ "GO:0001816" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23071\" xsd:anyURI" ]
pg
2022-03-24T07:11:34Z
false
true
8
GO:0140780
140,780
obsolete modulation by symbiont of host system process
biological_process
OBSOLETE. The process in which a symbiont organism effects a change in an anatomical system process of its host organism.
[ "GOC:pg" ]
This term was obsoleted because it is not sufficiently precise.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23627\" xsd:anyURI" ]
pg
2022-03-28T09:54:08Z
true
true
3
GO:0140781
140,781
ilicicolin H biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of ilicicolin H, a 4-hydroxy-2-pyridone alkaloid that has potent and broad antifungal activities by inhibiting the mitochondrial respiration chain.
[ "PMID:30905148", "PMID:31216742", "PMID:34947016" ]
null
[ "ilicicolin H anabolism", "ilicicolin H biosynthesis", "ilicicolin H formation", "ilicicolin H synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009821", "GO:0030639", "GO:0042181", "GO:0043386", "GO:0046189", "GO:0072525" ]
[]
[]
[]
[ "GO:0009821", "GO:0030639", "GO:0042181", "GO:0043386", "GO:0046189", "GO:0072525" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22982\" xsd:anyURI" ]
pg
2022-03-31T11:15:26Z
false
true
4
GO:0140783
140,783
(M)-viriditoxin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of (M)-viriditoxin, a fungal secondary metabolite with antibacterial activity.
[ "PMID:31045362", "PMID:31304040" ]
null
[ "(M)-viriditoxin anabolism", "(M)-viriditoxin biosynthesis", "(M)-viriditoxin formation", "(M)-viriditoxin synthesis", "viriditoxin anabolism", "viriditoxin biosynthesis", "viriditoxin formation", "viriditoxin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "BROAD", "BROAD", "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0030639", "GO:0043386", "GO:0046189", "GO:1901503" ]
[]
[]
[]
[ "GO:0030639", "GO:0043386", "GO:0046189", "GO:1901503" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22448\" xsd:anyURI" ]
pg
2022-03-31T11:41:47Z
false
true
5
GO:0140784
140,784
metal ion sensor activity
molecular_function
Binding to and responding, e.g. by conformational change, to changes in the cellular level of a metal ion.
[ "GOC:pg" ]
null
[]
[]
[]
[]
[]
[ "GO:0140299" ]
[]
[]
[]
[ "GO:0140299" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23126\" xsd:anyURI" ]
pg
2022-04-01T08:40:55Z
false
true
6
GO:0140785
140,785
amino acid sensor activity
molecular_function
Binding to and responding, e.g. by conformational change, to changes in the cellular level of an amino acid.
[ "GOC:pg" ]
null
[ "amino acid sensing activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140299" ]
[]
[]
[]
[ "GO:0140299" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23126\" xsd:anyURI" ]
pg
2022-04-01T08:44:02Z
false
true
5
GO:0140786
140,786
glutamine sensor activity
molecular_function
Binding to and responding, e.g. by conformational change, to changes in the cellular level of glutamine.
[ "PMID:34535752" ]
null
[ "glutamine sensing activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140785" ]
[]
[]
[]
[ "GO:0140785" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23124\" xsd:anyURI" ]
pg
2022-04-01T08:54:10Z
false
true
1
GO:0140787
140,787
phosphate ion uniporter activity
molecular_function
Catalysis of the active transport of a phosphate ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
[ "PMID:29642010" ]
null
[]
[]
[]
[]
[]
[ "GO:0005315", "GO:0022810" ]
[]
[]
[]
[ "GO:0005315", "GO:0022810" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:32823", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23132\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27521\" xsd:anyURI" ]
pg
2022-04-05T07:42:20Z
false
true
3
GO:0140788
140,788
L-glutamate uniporter activity
molecular_function
Catalysis of the active transport of a L-glutamate across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
[ "PMID:27133463", "PMID:29642010" ]
null
[ "glutamate uniporter activity" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0005313", "GO:0022810" ]
[]
[]
[]
[ "GO:0005313", "GO:0022810" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:66336", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23143\" xsd:anyURI" ]
pg
2022-04-06T07:05:14Z
false
true
4
GO:0140789
140,789
histone phosphatase activity
molecular_function
Catalysis of the reaction: a phosphorylated histone + H2O = a protein + phosphate.
[ "PMID:19351884" ]
null
[]
[]
[]
[]
[]
[ "GO:0004721", "GO:0140993" ]
[]
[]
[]
[ "GO:0004721", "GO:0140993" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23148\" xsd:anyURI" ]
pg
2022-04-06T08:08:00Z
false
true
8
GO:0140790
140,790
obsolete histone serine/threonine phosphatase activity
molecular_function
OBSOLETE. Catalysis of the reaction: histone serine phosphate + H2O = histone serine + phosphate, and histone threonine phosphate + H2O = histone threonine + phosphate.
[ "PMID:18614045" ]
This term was obsoleted because it represents an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0140789" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23148\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24397\" xsd:anyURI" ]
pg
2022-04-06T08:16:16Z
true
true
9
GO:0140791
140,791
histone H2AXS139 phosphatase activity
molecular_function
Catalysis of the reaction: histone H2AX serine phosphate (position 139) + H2O = histone H2AX serine (position 139) + phosphate.
[ "PMID:18614045" ]
Note that the residue position corresponds to the canonical human H2AX histone (UniProtKB:P16104); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across diff...
[ "histone H2-S140 serine phosphatase activity", "histone H2S140 phosphatase activity", "histone serine phosphatase activity (H2-S140 specific)" ]
[ "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0140789" ]
[]
[]
[]
[ "GO:0140789" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.3.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23148\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25037\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", ...
pg
2022-04-06T08:16:16Z
false
true
5
GO:0140792
140,792
obsolete histone tyrosine phosphatase activity
molecular_function
OBSOLETE. Catalysis of the reaction: histone tyrosine phosphate + H2O = histone tyrosine + phosphate.
[ "PMID:19234442", "PMID:19351884" ]
This term was obsoleted because it represents an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0140789" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23148\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24397\" xsd:anyURI" ]
pg
2022-04-06T08:20:40Z
true
true
4
GO:0140793
140,793
histone H2AXY142 phosphatase activity
molecular_function
Catalysis of the reaction: histone H2AX tyrosine phosphate (position 142) + H2O = histone H2AX tyrosine (position 142) + phosphate.
[ "PMID:19234442", "PMID:19351884" ]
Note that the residue position corresponds to the canonical human H2AX histone (UniProtKB:P16104); this residue is conserved in mammals, but missing from tetrahymena. This residue is present in Drosophila histone H2AV. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each h...
[ "histone H2-Y142 phosphatase activity", "histone H2Y142 phosphatase activity", "histone tyrosine phosphatase activity (H2-Y142 specific)" ]
[ "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0140789" ]
[]
[]
[]
[ "GO:0140789" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.3.48", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23148\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25037\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", ...
pg
2022-04-06T08:20:40Z
false
true
3
GO:0140794
140,794
histone arginine deiminase activity
molecular_function
Catalysis of the reaction: H2O + histone 3 L-arginyl = histone 3 L-citrullyl + NH4+, resulting in histone citrullination.
[ "PMID:15339660" ]
The substrate for histone deiminase may be methyl-arginine, rather than arginine (see PMID:35197210 and PMID:16567635).
[ "histone citrullination", "histone-arginine deiminase activity" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0004668", "GO:0140993" ]
[]
[]
[]
[ "GO:0004668", "GO:0140993" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23152\" xsd:anyURI" ]
pg
2022-04-06T13:07:02Z
false
true
5
GO:0140795
140,795
histone H3R2 arginine deiminase activity
molecular_function
Catalysis of the reaction: H2O + histone H3 L-arginyl (position 2)= histone H3 L-citrullyl (position 2) + NH4+, resulting in histone H3 citrullination at position 2.
[ "PMID:15339660" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "H3-R2 citrullination", "histone H3-R2 arginine deiminase activity", "histone-arginine deiminase activity (H3-R2 specific)" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141057" ]
[]
[]
[]
[ "GO:0141057" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.5.3.15", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23152\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-04-06T13:10:24Z
false
true
9
GO:0140796
140,796
histone H3R8 arginine deiminase activity
molecular_function
Catalysis of the reaction: H2O + histone H3 L-arginyl (position 8)= histone H3 L-citrullyl (position 8) + NH4+, resulting in histone H3 citrullination at position 8.
[ "PMID:15339660" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "H3-R8 citrullination", "histone H3-R8 arginine deiminase activity", "histone-arginine deiminase activity (H3-R8 specific)" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141057" ]
[]
[]
[]
[ "GO:0141057" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.5.3.15", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23152\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-04-06T13:11:13Z
false
true
3
GO:0140797
140,797
histone H3R17 arginine deiminase activity
molecular_function
Catalysis of the reaction: H2O + histone H3 L-arginyl (position 17)= histone H3 L-citrullyl (position 17) + NH4+, resulting in histone H3 citrullination at position 17.
[ "PMID:15339660" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "H3-R17 citrullination", "histone H3-R17 arginine deiminase activity", "histone-arginine deiminase activity (H3-R17 specific)" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141057" ]
[]
[]
[]
[ "GO:0141057" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.5.3.15", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23152\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-04-06T13:12:15Z
false
true
2
GO:0140799
140,799
glycine:proton antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + H+(in) = glycine(in) + H+(out).
[ "PMID:16701208", "PMID:26912364" ]
null
[]
[]
[]
[]
[]
[ "GO:0015078", "GO:0015187", "GO:0140848" ]
[]
[]
[]
[ "GO:0015078", "GO:0015187", "GO:0140848" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23160\" xsd:anyURI" ]
pg
2022-04-07T16:05:04Z
false
true
4
GO:0140800
140,800
gamma-aminobutyric acid:proton antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4-aminobutanoate(out) + H+(in) = 4-aminobutanoate(in) + H+(out).
[ "PMID:16701208", "PMID:26912364", "PMID:27601664" ]
null
[]
[]
[]
[]
[]
[ "GO:0015078", "GO:0015185", "GO:0015355", "GO:0140848" ]
[]
[]
[]
[ "GO:0015078", "GO:0015185", "GO:0015355", "GO:0140848" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23159\" xsd:anyURI" ]
pg
2022-04-07T16:08:18Z
false
true
3
GO:0140801
140,801
histone H2AXY142 kinase activity
molecular_function
Catalysis of the reaction: histone H2AX-tyrosine (position 142) + ATP = (histone H2AX-phosphotyrosine (position 142) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 142 of histone variant H2AX.
[ "PMID:19092802" ]
Note that the residue position corresponds to the canonical human H2AX histone (UniProtKB:P16104); this residue is conserved in mammals, but missing from tetrahymena. This residue is present in Drosophila histone H2AV. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each h...
[ "gamma-H2AX-S142 kinase activity", "histone H2AX-Y142 kinase activity", "histone H2AY142 kinase activity", "histone kinase activity (H2AX-Y142 specific)" ]
[ "EXACT", "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0004713", "GO:0141003" ]
[]
[]
[]
[ "GO:0004713", "GO:0141003" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:10596", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23170\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-04-08T16:17:40Z
false
true
2
GO:0140802
140,802
NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: [protein]-C-terminal glycine + NAD+ = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide.
[ "PMID:28525742", "RHEA:58268" ]
null
[]
[]
[]
[]
[ "RHEA:58268" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:58268", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-02T06:45:52Z
false
true
3
GO:0140803
140,803
NAD+-protein-cysteine ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: L-cysteinyl-[protein] + NAD+ = H+ + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein].
[ "PMID:25043379", "RHEA:56612" ]
null
[]
[]
[]
[]
[ "RHEA:56612" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:56612", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-02T06:46:09Z
false
true
4
GO:0140804
140,804
NAD+-protein-lysine ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: L-lysyl-[protein] + NAD+ = H+ + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] + nicotinamide.
[ "PMID:25043379", "RHEA:58220" ]
null
[]
[]
[]
[]
[ "RHEA:58220" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:58220", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-02T06:46:22Z
false
true
7
GO:0140805
140,805
NAD+-protein-serine ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: L-seryl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-seryl-[protein].
[ "PMID:32028527", "PMID:33186521", "RHEA:58232" ]
null
[]
[]
[]
[]
[ "RHEA:58232" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:58232", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-02T06:46:35Z
false
true
2
GO:0140806
140,806
NAD+-protein-aspartate ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: L-aspartyl-[protein] + NAD+ = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide.
[ "PMID:19764761", "PMID:25043379", "RHEA:54424" ]
null
[]
[]
[]
[]
[ "RHEA:54424" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:54424", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28324\" xsd:anyURI" ]
pg
2022-05-02T06:46:47Z
false
true
1
GO:0140807
140,807
NAD+-protein-glutamate ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: L-glutamyl-[protein] + NAD+ = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide.
[ "PMID:19764761", "PMID:25043379", "RHEA:58224" ]
null
[]
[]
[]
[]
[ "RHEA:58224" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:58224", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI" ]
pg
2022-05-02T06:47:00Z
false
true
8
GO:0140808
140,808
NAD+-protein-tyrosine ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: L-tyrosyl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein].
[ "PMID:29954836", "PMID:30257210", "RHEA:58236" ]
null
[]
[]
[]
[]
[ "RHEA:58236" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:58236", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-02T06:47:12Z
false
true
1
GO:0140810
140,810
histone H1R54 arginine deiminase activity
molecular_function
Catalysis of the reaction: H2O + histone H1 L-arginyl (position 54)= histone H1 L-citrullyl (position 54) + NH4+, resulting in histone H1 citrullination at position 54.
[ "PMID:24463520" ]
The substrate for histone deiminase may be methyl-arginine, rather than arginine (see PMID:35197210 and PMID:16567635).
[ "H1-R54 citrullination", "histone H1-R54 deiminase activity", "histone-arginine deiminase activity (H1-R54 specific)" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0140794" ]
[]
[]
[]
[ "GO:0140794" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.5.3.15", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23152\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-11T10:11:08Z
false
true
1
GO:0140812
140,812
orotate:monoatomic anion antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: orotate(out) + anion (in) = orotate (in) + anion (out).
[ "PMID:21350910", "PMID:35144162" ]
null
[ "orotate:anion antiporter activity", "orotate:organic anion antiporter activity" ]
[ "BROAD", "NARROW" ]
[]
[]
[]
[ "GO:0008509", "GO:0015297", "GO:0015355" ]
[]
[]
[]
[ "GO:0008509", "GO:0015297", "GO:0015355" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23307\" xsd:anyURI" ]
pg
2022-05-12T05:51:36Z
false
true
6
GO:0140813
140,813
urate:monoatomic anion antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urate(out) + anion (in) = urate (in) + anion (out).
[ "PMID:12024214", "PMID:18411268" ]
null
[ "urate:anion antiporter activity", "urate:organic anion antiporter activity" ]
[ "BROAD", "NARROW" ]
[]
[]
[]
[ "GO:0008509", "GO:0015297" ]
[ "part_of GO:0015747" ]
[ "part_of" ]
[ "GO:0015747" ]
[ "GO:0008509", "GO:0015297", "GO:0015747" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23306\" xsd:anyURI" ]
pg
2022-05-12T05:57:12Z
false
true
6
GO:0140814
140,814
glycine betaine:sodium:chloride symporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + Na+(out) + Cl-(out)= glycine betaine(in) + Na+(in) + Cl-(in).
[ "PMID:10358010" ]
null
[ "sodium/chloride-dependent glycine betaine transporter activity" ]
[ "BROAD" ]
[]
[]
[ "RHEA:71175" ]
[ "GO:0015199", "GO:0015378" ]
[ "part_of GO:0031460" ]
[ "part_of" ]
[ "GO:0031460" ]
[ "GO:0015199", "GO:0015378", "GO:0031460" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:71175", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23298\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-12T06:05:59Z
false
true
7
GO:0140815
140,815
NAD+-protein-histidine ADP-ribosyltransferase activity
molecular_function
Catalysis of the reaction: L-histidyl-[protein] + NAD+ = H+ + Nt-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide.
[ "PMID:35393539", "RHEA:72071" ]
null
[]
[]
[]
[]
[ "RHEA:72071" ]
[ "GO:1990404" ]
[]
[]
[]
[ "GO:1990404" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:72071", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23309\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-12T07:49:41Z
false
true
9
GO:0140816
140,816
NAD+-histone H2BS6 serine ADP-ribosyltransferase activity
molecular_function
Catalysis of the transfer of ADP-ribose groups to the serine-6 or an equivalent residue of the N-terminal tail of histone H2B.
[ "PMID:34874266" ]
Note that the residue position corresponds to the canonical human H2B histone (UniProtKB:P62807); the N-terminus of histone H2B is divergent across eukaryotes; make sure that the paper clearly references the human protein for the position of this modification to use this term. Residue 1 is the first residue following r...
[ "NAD+-histone H2B-S6 serine ADP-ribosyltransferase activity", "NAD+-histone-serine ADP-ribosyltransferase activity (H2B-S6 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0140805" ]
[]
[]
[]
[ "GO:0140805" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:58232", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23309\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-05-12T07:52:48Z
false
true
3
GO:0140817
140,817
NAD+-histone H3S10 serine ADP-ribosyltransferase activity
molecular_function
Catalysis of the transfer of ADP-ribose groups to the serine-10 or an equivalent residue of the N-terminal tail of histone H3.
[ "PMID:34874266" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "NAD+-histone H3-S10 serine ADP-ribosyltransferase activity", "NAD+-histone-serine ADP-ribosyltransferase activity (H3-S10 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0140805" ]
[]
[]
[]
[ "GO:0140805" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:58232", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23309\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-05-12T07:53:59Z
false
true
7
GO:0140818
140,818
mRNA 5'-triphosphate monophosphatase activity
molecular_function
A 5'-end triphospho-[mRNA] + H2O = a 5'-end diphospho-[mRNA] + H+ + phosphate.
[ "PMID:9473487" ]
null
[ "mRNA 5'-phosphatase activity" ]
[ "EXACT" ]
[]
[]
[ "EC:3.6.1.74", "MetaCyc:POLYNUCLEOTIDE-5-PHOSPHATASE-RXN", "RHEA:11008", "RHEA:67004" ]
[ "GO:0016462", "GO:0140098" ]
[]
[]
[]
[ "GO:0016462", "GO:0140098" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.6.1.74", "skos:exactMatch RHEA:67004", "skos:narrowMatch RHEA:11008", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23319\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25810\" xsd:anyURI", "term_tracker_item \"https:/...
pg
2022-05-16T06:01:07Z
false
true
2
GO:0140819
140,819
UDP-beta-L-arabinofuranose transporter activity
molecular_function
Enables the transfer of UDP-beta-L-arabinofuranose from one side of a membrane to the other.
[ "PMID:28373556" ]
null
[]
[]
[]
[]
[]
[ "GO:0015165" ]
[]
[]
[]
[ "GO:0015165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21524\" xsd:anyURI" ]
pg
2022-05-16T06:45:42Z
false
true
1
GO:0140820
140,820
cytosol to Golgi apparatus transport
biological_process
The directed movement of substances from the cytosol into the Golgi apparatus of a cell.
[ "PMID:28373556" ]
null
[]
[]
[]
[]
[]
[ "GO:0010496", "GO:0055085" ]
[]
[]
[]
[ "GO:0010496", "GO:0055085" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21524\" xsd:anyURI" ]
pg
2022-05-16T06:59:22Z
false
true
3
GO:0140821
140,821
UDP-beta-L-arabinofuranose import into Golgi lumen
biological_process
The directed movement of UDP-beta-L-arabinofuranose from the cytosol to the Golgi apparatus of a cell.
[ "PMID:28373556" ]
null
[ "cytosol to Golgi apparatus UDP-beta-L-arabinofuranose transport" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0015711", "GO:0090481", "GO:0140820" ]
[]
[]
[]
[ "GO:0015711", "GO:0090481", "GO:0140820" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21524\" xsd:anyURI" ]
pg
2022-05-16T06:59:22Z
false
true
4
GO:0140822
140,822
NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity
molecular_function
Catalysis of the transfer of ADP-ribose groups to the glutamate-35 residue of the N-terminal tail of histone H2B (or an equivalent residue).
[ "PMID:32822587" ]
Note that the residue position corresponds to the canonical human H2B histone (UniProtKB:P62807); this residue is conserved across all eukaryotes, but seems to be missing from Dictyostelium. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multipl...
[ "NAD+-histone H2B-E35 glutamate ADP-ribosyltransferase activity", "NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E35 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0140807" ]
[]
[]
[]
[ "GO:0140807" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:58224", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23323\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-05-17T13:57:05Z
false
true
8
GO:0140823
140,823
histone H2BS36 kinase activity
molecular_function
Catalysis of the reaction: histone H2B-serine (position 36) + ATP = histone H2B-phosphoserine (position 36) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 36 of histone H2B.
[ "PMID:32822587" ]
Note that the residue position corresponds to the canonical human H2B histone (UniProtKB:P62807); this residue is conserved across all animals, and is replaced by a Thr in plants and fungi, but seems to be missing from Dictyostelium. Residue 1 is the first residue following removal of the initiating Methionine (Met). N...
[ "histone H2B-S36 kinase activity", "histone kinase activity (H2B-S36 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004674", "GO:0140998" ]
[]
[]
[]
[ "GO:0004674", "GO:0140998" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.1", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23323\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-05-17T13:58:11Z
false
true
6
GO:0140824
140,824
thioredoxin-dependent peroxiredoxin activity
molecular_function
Catalysis of the reaction: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O.
[ "PMID:12707274", "PMID:19820102", "RHEA:62620" ]
null
[]
[]
[]
[]
[ "EC:1.11.1.24", "RHEA:62620", "RHEA:63840", "RHEA:63844" ]
[ "GO:0051920" ]
[]
[]
[]
[ "GO:0051920" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.11.1.24", "skos:exactMatch RHEA:62620", "skos:narrowMatch RHEA:63840", "skos:narrowMatch RHEA:63844", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23121\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyUR...
pg
2022-05-18T14:25:09Z
false
true
7
GO:0140825
140,825
lactoperoxidase activity
molecular_function
Catalysis of the reaction: 2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O.
[ "PMID:19339248", "RHEA:56136" ]
null
[ "heme peroxidase activity", "peroxidase activity" ]
[ "RELATED", "BROAD" ]
[]
[]
[ "EC:1.11.1.7", "MetaCyc:PEROXID-RXN", "RHEA:56136" ]
[ "GO:0004601" ]
[]
[]
[]
[ "GO:0004601" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.11.1.7", "skos:exactMatch RHEA:56136", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23121\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25776\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontol...
pg
2022-05-18T14:39:20Z
false
true
2
GO:0140826
140,826
zinc:proton antiporter activity
molecular_function
Enables the transfer of zinc from one side of a membrane to the other according to the reaction: H+(out) + Zn2+(in) = H+(in) + Zn2+(out).
[ "PMID:19366695", "PMID:30893306" ]
Some transporters exchange 1 H+ for a Zn2+ while others are electroneutral and exchange 2 H+.
[]
[]
[]
[]
[ "RHEA:28839", "RHEA:72627" ]
[ "GO:0005385", "GO:0051139" ]
[]
[]
[]
[ "GO:0005385", "GO:0051139" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch RHEA:28839", "skos:narrowMatch RHEA:72627", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23359\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23874\" xsd:anyURI" ]
pg
2022-05-20T05:22:59Z
false
true
4