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GO

Dataset card Data Studio Files
xet
 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0140827
140,827
zinc chaperone activity
molecular_function
Binding to and delivering zinc ions to a target protein.
[ "PMID:35584675" ]
null
[ "zinc carrier activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0016530" ]
[ "has_part GO:0008270" ]
[ "has_part" ]
[ "GO:0008270" ]
[ "GO:0008270", "GO:0016530" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23363\" xsd:anyURI" ]
pg
2022-05-20T06:19:17Z
false
true
8
GO:0140828
140,828
metal cation:monoatomic cation antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(in) = solute(in) + Na+(out).
[ "GOC:pg" ]
null
[ "solute:metal cation antiporter activity" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0015297", "GO:0046873" ]
[]
[]
[]
[ "GO:0015297", "GO:0046873" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24479\" xsd:anyURI" ]
pg
2022-05-23T14:30:46Z
false
true
6
GO:0140829
140,829
bicarbonate:monoatomic anion antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(in) + HCO3-(out) = solute(out) + HCO3-(in).
[ "PMID:12440690" ]
null
[ "bicarbonate:anion antiporter activity", "hydrogencarbonate:monoatomic anion antiporter activity" ]
[ "BROAD", "EXACT" ]
[]
[]
[ "TC:2.A.31.1.1" ]
[ "GO:0008509", "GO:0015106", "GO:0015297" ]
[]
[]
[]
[ "GO:0008509", "GO:0015106", "GO:0015297" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26780\" xsd:anyURI" ]
pg
2022-05-24T12:25:35Z
false
true
2
GO:0140830
140,830
L-glutamine, sodium:proton antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-glutamine(out) + Na+(out) = H+(out) + L-glutamine(in) + Na+(in).
[ "PMID:10619430", "PMID:11742981", "PMID:11850497" ]
null
[]
[]
[]
[]
[ "RHEA:71127" ]
[ "GO:0015186", "GO:0015385", "GO:0140848" ]
[]
[]
[]
[ "GO:0015186", "GO:0015385", "GO:0140848" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:71127", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23382\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-24T12:29:37Z
false
true
6
GO:0140831
140,831
L-asparagine, sodium:proton antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-asparagine(out) + Na+(out) = H+(out) + L-asparagine(in) + Na+(in).
[ "PMID:10619430", "PMID:11742981" ]
null
[]
[]
[]
[]
[ "RHEA:71131" ]
[ "GO:0015182", "GO:0015385", "GO:0140848" ]
[]
[]
[]
[ "GO:0015182", "GO:0015385", "GO:0140848" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:71131", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23383\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-24T12:35:49Z
false
true
2
GO:0140832
140,832
L-histidine, sodium:proton antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-histidine(out) + Na+(out) = H+(out) + L-histidine(in) + Na+(in).
[ "PMID:10619430", "PMID:11742981" ]
null
[]
[]
[]
[]
[ "RHEA:71135" ]
[ "GO:0005290", "GO:0015385", "GO:0045119", "GO:0140848" ]
[]
[]
[]
[ "GO:0005290", "GO:0015385", "GO:0045119", "GO:0140848" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:71135", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23384\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-05-24T12:37:29Z
false
true
9
GO:0140833
140,833
RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
molecular_function
Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphotyrosine (position 1).
[ "PMID:28248323" ]
null
[ "RNA polymerase II C-terminal domain Y1 kinase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.23", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T13:52:02Z
false
true
4
GO:0140834
140,834
RNA polymerase II CTD heptapeptide repeat S2 kinase activity
molecular_function
Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 2).
[ "PMID:28248323" ]
null
[ "RNA polymerase II C-terminal domain S2 kinase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.23", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T13:52:21Z
false
true
3
GO:0140835
140,835
RNA polymerase II CTD heptapeptide repeat T4 kinase activity
molecular_function
Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphothreonine (position 4).
[ "PMID:28248323" ]
null
[ "RNA polymerase II C-terminal domain T4 kinase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.23", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T13:52:52Z
false
true
9
GO:0140836
140,836
RNA polymerase II CTD heptapeptide repeat S5 kinase activity
molecular_function
Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 5).
[ "PMID:28248323" ]
null
[ "RNA polymerase II C-terminal domain S5 kinase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.23", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T13:53:11Z
false
true
6
GO:0140837
140,837
RNA polymerase II CTD heptapeptide repeat S7 kinase activity
molecular_function
Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 7).
[ "PMID:28248323" ]
null
[ "RNA polymerase II C-terminal domain S7 kinase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[ "GO:0008353" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.23", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T13:53:35Z
false
true
5
GO:0140838
140,838
RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) = RNA polymerase II large subunit trans-proline (omega=0).
[ "PMID:28248323" ]
null
[]
[]
[]
[]
[]
[ "GO:0003755", "GO:0140994" ]
[]
[]
[]
[ "GO:0003755", "GO:0140994" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI" ]
pg
2022-05-24T14:17:37Z
false
true
3
GO:0140839
140,839
RNA polymerase II CTD heptapeptide repeat P3 isomerase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 3) = RNA polymerase II large subunit trans-proline (omega=0) (position 3).
[ "PMID:28248323" ]
null
[ "RNA polymerase II C-terminal domain P3 isomerase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140838" ]
[]
[]
[]
[ "GO:0140838" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:5.2.1.8", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T14:18:06Z
false
true
1
GO:0140840
140,840
RNA polymerase II CTD heptapeptide repeat P6 isomerase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 6) = RNA polymerase II large subunit trans-proline (omega=0) (position 6).
[ "PMID:28248323" ]
null
[ "RNA polymerase II C-terminal domain P6 isomerase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140838" ]
[]
[]
[]
[ "GO:0140838" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:5.2.1.8", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T14:18:25Z
false
true
5
GO:0140841
140,841
RNA polymerase II C-terminal domain O-GlcNAc transferase activity
molecular_function
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine.
[ "PMID:22605332" ]
null
[]
[]
[]
[]
[]
[ "GO:0097363" ]
[]
[]
[]
[ "GO:0097363" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI" ]
pg
2022-05-24T14:27:41Z
false
true
8
GO:0140842
140,842
RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity
molecular_function
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 5).
[ "PMID:22605332" ]
null
[]
[]
[]
[]
[]
[ "GO:0140841" ]
[]
[]
[]
[ "GO:0140841" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.4.1.255", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T14:27:57Z
false
true
6
GO:0140843
140,843
RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity
molecular_function
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 7).
[ "PMID:22605332" ]
null
[]
[]
[]
[]
[]
[ "GO:0140841" ]
[]
[]
[]
[ "GO:0140841" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.4.1.255", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23389\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
pg
2022-05-24T14:28:06Z
false
true
7
GO:0140844
140,844
NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity
molecular_function
Catalysis of the transfer of ADP-ribose groups to the glutamate-2 residue of the N-terminal tail of histone H2B (or an equivalent residue).
[ "PMID:27530147" ]
Note that the residue position corresponds to the canonical human H2B histone (UniProtKB:P62807); the N-terminus of histone H2B is divergent across eukaryotes; make sure that the paper clearly references the human protein for the position of this modification to use this term. Corresponds to histone H2BE18 in Dictyost...
[ "NAD+-histone H2B-E2 glutamate ADP-ribosyltransferase activity", "NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E2 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0140807" ]
[]
[]
[]
[ "GO:0140807" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:58224", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23377\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-05-25T07:28:00Z
false
true
3
GO:0140845
140,845
regulation of promoter clearance from RNA polymerase II promoter
biological_process
A process that modulates the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II.
[ "PMID:28248323" ]
null
[]
[]
[]
[]
[]
[ "GO:2001141" ]
[ "regulates GO:0001111" ]
[ "regulates" ]
[ "GO:0001111" ]
[ "GO:0001111", "GO:2001141" ]
[ "GO:0065007", "regulates GO:0001111" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23388\" xsd:anyURI" ]
pg
2022-05-25T07:54:33Z
false
true
3
GO:0140846
140,846
positive regulation of promoter clearance from RNA polymerase II promoter
biological_process
A process that activates or increases the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II.
[ "PMID:28248323" ]
null
[]
[]
[]
[]
[]
[ "GO:0140845", "GO:1902680" ]
[ "positively_regulates GO:0001111" ]
[ "positively_regulates" ]
[ "GO:0001111" ]
[ "GO:0001111", "GO:0140845", "GO:1902680" ]
[ "GO:0065007", "positively_regulates GO:0001111" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23388\" xsd:anyURI" ]
pg
2022-05-25T07:54:33Z
false
true
2
GO:0140847
140,847
negative regulation of promoter clearance from RNA polymerase II promoter
biological_process
A process that stops, prevents or reduces the transition from the initiation to the elongation phases of transcription by RNA polymerase II.
[ "PMID:28248323" ]
null
[]
[]
[]
[]
[]
[ "GO:0140845", "GO:1902679" ]
[ "negatively_regulates GO:0001111" ]
[ "negatively_regulates" ]
[ "GO:0001111" ]
[ "GO:0001111", "GO:0140845", "GO:1902679" ]
[ "GO:0065007", "negatively_regulates GO:0001111" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23388\" xsd:anyURI" ]
pg
2022-05-25T07:54:33Z
false
true
8
GO:0140848
140,848
amino acid:monoatomic cation antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + monoatomic cation(in) = solute(in) + monoatomic cation(out). Monoatomic cations include H+, Mg2+, Ca2+, etc.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0008324", "GO:0015171", "GO:0015297" ]
[]
[]
[]
[ "GO:0008324", "GO:0015171", "GO:0015297" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24479\" xsd:anyURI" ]
pg
2022-05-30T13:15:04Z
false
true
3
GO:0140850
140,850
histone H2B C-terminal K residue ubiquitin ligase activity
molecular_function
Catalysis of the transfer of a ubiquitin molecule to a histone 2B at the conserved C-terminal lysine (K) residue. The last K residue is at position 119 in fission yeast, 123 in budding yeast, and 120 in mammals.
[ "PMID:17363370", "PMID:28624371" ]
null
[ "histone H2B conserved C-terminal lysine ubiquitin ligase activity", "histone H2B-K120 ubiquitin ligase activity", "histone H2BK120 ubiquitin ligase activity", "histone ubiquitin ligase activity (H2B-K120 specific)" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141054" ]
[]
[]
[]
[ "GO:0141054" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24014\" xsd:anyURI" ]
pg
2022-06-13T09:32:28Z
false
true
3
GO:0140851
140,851
histone H3K14 ubiquitin ligase activity
molecular_function
Catalysis of the transfer of a ubiquitin molecule to histone 3 at the lysine-14 residue.
[ "PMID:28624371", "PMID:31468675", "PMID:34010645" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "histone H3-K14 ubiquitin ligase activity", "histone ubiquitin ligase activity (H3-K14 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141055" ]
[]
[]
[]
[ "GO:0141055" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-06-13T10:34:13Z
false
true
3
GO:0140852
140,852
histone ubiquitin ligase activity
molecular_function
Catalysis of the transfer of ubiquitin to a histone substrate.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0061630", "GO:0140993" ]
[]
[]
[]
[ "GO:0061630", "GO:0140993" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI" ]
pg
2022-06-13T10:38:05Z
false
true
1
GO:0140853
140,853
cholesterol-protein transferase activity
molecular_function
Catalysis of the reaction: cholesterol + glycyl-L-cysteinyl-[protein] + H+ = [protein]-C-terminal glycyl cholesterol ester + N-terminal L-cysteinyl-[protein].
[ "PMID:8824192", "RHEA:59504" ]
null
[ "cholesterol transferase activity" ]
[ "BROAD" ]
[]
[]
[ "RHEA:59504" ]
[ "GO:0016740", "GO:0140096" ]
[]
[]
[]
[ "GO:0016740", "GO:0140096" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:59504", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23427\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27191\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-06-13T15:08:54Z
false
true
4
GO:0140854
140,854
interleukin-19-mediated signaling pathway
biological_process
The series of molecular signals initiated by interleukin-19 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
[ "PMID:34052656" ]
null
[ "IL19-mediated signalling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[]
[]
[]
pg
2022-06-16T08:33:15Z
false
true
9
GO:0140855
140,855
histone H3S57 kinase activity
molecular_function
Catalysis of the reaction: histone H3-serine (position 57) + ATP = histone H3-phosphoserine (position 57) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 57 of histone H3.
[ "PMID:24820035" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "histone kinase activity (H3-S57 specific)", "histone serine kinase activity (H3-S57 specific)", "histone-serine kinase activity (H3-S57 specific)" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004674", "GO:0140996" ]
[]
[]
[]
[ "GO:0004674", "GO:0140996" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.1", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23503\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-06-16T11:16:11Z
false
true
6
GO:0140856
140,856
histone H2AK13 ubiquitin ligase activity
molecular_function
Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-13 residue.
[ "PMID:22980979", "PMID:28624371" ]
Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across dif...
[ "histone ubiquitin ligase activity (H2A-K13 specific)" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch KEGG_REACTION:R03876", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:...
pg
2022-06-20T12:45:05Z
false
true
4
GO:0140857
140,857
histone H3T45 kinase activity
molecular_function
Catalysis of the reaction: histone H3-threonine (position 45) + ATP = histone H3-phosphothreonine (position 45) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 45 of histone H3.
[ "PMID:24820035" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "histone kinase activity (H3-T45 specific)", "histone threonine kinase activity (H3-T45 specific)", "histone-threonine kinase activity (H3-T45 specific)" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004674", "GO:0140996" ]
[]
[]
[]
[ "GO:0004674", "GO:0140996" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.1", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23503\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
pg
2022-06-16T11:18:51Z
false
true
9
GO:0140858
140,858
histone H2AK15 ubiquitin ligase activity
molecular_function
Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-15 residue.
[ "PMID:22980979", "PMID:28624371" ]
Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across dif...
[ "histone ubiquitin ligase activity (H2A-K15 specific)" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch KEGG_REACTION:R03876", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:...
pg
2022-06-20T12:45:05Z
false
true
6
GO:0140860
140,860
(3R)-2'-hydroxyisoflavanone reductase (NADP+) activity
molecular_function
Catalysis of the reaction: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP+ = a (3R)-2'-hydroxyisoflavanone + H+ + NADPH.
[ "PMID:7625843", "RHEA:56284" ]
null
[ "vestitone reductase activity" ]
[ "NARROW" ]
[]
[]
[ "EC:1.1.1.348", "MetaCyc:RXN-18747", "RHEA:35403", "RHEA:56284" ]
[ "GO:0016616" ]
[]
[]
[]
[ "GO:0016616" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.1.1.348", "skos:exactMatch MetaCyc:RXN-18747", "skos:exactMatch RHEA:56284", "skos:narrowMatch RHEA:35403", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23521\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28324\" xsd...
pg
2022-06-20T14:44:54Z
false
true
3
GO:0140861
140,861
DNA repair-dependent chromatin remodeling
biological_process
A chromatin remodeling process that allows DNA repair enzyme to access genomic DNA and repair DNA lesions.
[ "PMID:15528408", "PMID:28053344", "PMID:29095668", "PMID:35689883" ]
null
[ "DNA damage-dependent chromatin remodelling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006338" ]
[ "part_of GO:0006974" ]
[ "part_of" ]
[ "GO:0006974" ]
[ "GO:0006338", "GO:0006974" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23518\" xsd:anyURI" ]
pg
2022-06-21T05:58:39Z
false
true
8
GO:0140862
140,862
histone H2AK119 ubiquitin ligase activity
molecular_function
Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-119 residue.
[ "PMID:22844243", "PMID:25470042", "PMID:28624371" ]
Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across dif...
[ "histone H2A-K119 ubiquitin ligase activity", "histone ubiquitin ligase activity (H2A-K119 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch KEGG_REACTION:R03876", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:...
pg
2022-06-20T12:45:05Z
false
true
8
GO:0140863
140,863
histone H2AK127 ubiquitin ligase activity
molecular_function
Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-127 residue.
[ "PMID:28624371" ]
Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is only present in vertebrates. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across differe...
[ "histone H2A-K127 ubiquitin ligase activity", "histone ubiquitin ligase activity (H2A-K127 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch KEGG_REACTION:R03876", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:...
pg
2022-06-20T12:45:05Z
false
true
6
GO:0140864
140,864
histone H2AK129 ubiquitin ligase activity
molecular_function
Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-129 residue.
[ "PMID:28624371" ]
Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is only present in vertebrates. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across differe...
[ "histone H2A-K129 ubiquitin ligase activity", "histone ubiquitin ligase activity (H2A-K129 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[ "GO:0141053" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch KEGG_REACTION:R03876", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:...
pg
2022-06-21T12:12:21Z
false
true
7
GO:0140865
140,865
interleukin-22-mediated signaling pathway
biological_process
The series of molecular signals initiated by interleukin-22 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
[ "PMID:34755534" ]
null
[ "IL-22-mediated signaling pathway", "interleukin-22-mediated signalling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23535\" xsd:anyURI" ]
pg
2022-06-22T11:15:07Z
false
true
1
GO:0140867
140,867
obsolete NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity
molecular_function
OBSOLETE. Catalysis of the transfer of ADP-ribose groups to the glutamate-18 residue of histone H2B (or an equivalent residue).
[ "PMID:28252050" ]
This term was obsoleted because it corresponds to the Dictyostelium position for NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity ; GO:0140844.
[ "NAD+-histone H2B-E18 glutamate ADP-ribosyltransferase activity", "NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E18 specific)" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0140844" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23551\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30583\" xsd:anyURI" ]
pg
2022-06-24T06:06:36Z
true
true
1
GO:0140868
140,868
obsolete 4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
molecular_function
OBSOLETE. Catalysis of the reaction: 3 H+ + 15-cis-4,4'-diapophytoene + 3 FAD = 4,4'-diapolycopene + 3 FADH2. This reaction consists of three successive dehydrogenations that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene...
[ "PMID:15933032" ]
This term was obsoleted because the reaction it represents may not be physiologically relevant.
[ "4,4'-diapophytoene desaturase activity" ]
[ "BROAD" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0102223" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23557\" xsd:anyURI" ]
pg
2022-06-24T13:47:06Z
true
true
8
GO:0140869
140,869
miRNA inhibitor activity via base-pairing
molecular_function
Stops, prevents or reduces the activity of miRNA-mediated gene silencing activity by base-pairing with a target miRNA. An example of this activity is mediated by long non-coding RNAs (lncRNAs).
[ "PMID:34454184" ]
This term is intended for regulatory non-coding RNAs that act by base-pairing with a target microRNA.
[ "base-pairing target-directed microRNA suppressor activity", "base-pairing target-directed miRNA suppressor activity", "miRNA base-pairing repressor activity", "miRNA binding involved in posttranscriptional gene silencing", "miRNA inhibitor activity", "miRNA sponge" ]
[ "RELATED", "RELATED", "NARROW", "EXACT", "BROAD", "NARROW" ]
[]
[]
[]
[ "GO:0035198", "GO:0140678" ]
[]
[]
[]
[ "GO:0035198", "GO:0140678" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23019\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24359\" xsd:anyURI" ]
pg
2022-07-04T12:23:27Z
false
true
2
GO:0140870
140,870
RNA polymerase inhibitor activity
molecular_function
Binds to and stops, prevents or reduces the activity of RNA polymerase.
[ "PMID:15300239", "PMID:18313387", "PMID:31048766" ]
null
[]
[]
[]
[]
[]
[ "GO:0004857" ]
[ "negatively_regulates GO:0097747" ]
[ "negatively_regulates" ]
[ "GO:0097747" ]
[ "GO:0004857", "GO:0097747" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23028\" xsd:anyURI" ]
pg
2022-07-04T14:26:28Z
false
true
9
GO:0140871
140,871
repressor of RNA polymerase inhibitor activity
molecular_function
Binds to and stops, prevents or reduces the activity of an RNA polymerase inhibitor.
[ "PMID:28475895", "PMID:31048766" ]
null
[]
[]
[]
[]
[]
[ "GO:0140678" ]
[ "negatively_regulates GO:0097747", "negatively_regulates GO:0140870" ]
[ "negatively_regulates", "negatively_regulates" ]
[ "GO:0097747", "GO:0140870" ]
[ "GO:0097747", "GO:0140678", "GO:0140870" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23028\" xsd:anyURI" ]
pg
2022-07-04T14:26:28Z
false
true
7
GO:0140873
140,873
paxilline biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of paxilline, a mycotoxin that acts as an inhibitor of mammalian maxi-K channels.
[ "PMID:23949005" ]
null
[ "paxilline anabolism", "paxilline biosynthesis", "paxilline formation", "paxilline synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-7493" ]
[ "GO:0009709", "GO:0016102", "GO:0042181", "GO:0043386", "GO:0120255", "GO:1902645" ]
[]
[]
[]
[ "GO:0009709", "GO:0016102", "GO:0042181", "GO:0043386", "GO:0120255", "GO:1902645" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23590\" xsd:anyURI" ]
pg
2022-07-05T07:12:13Z
false
true
1
GO:0140874
140,874
paraherquonin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture.
[ "PMID:27602587" ]
null
[ "paraherquonin anabolism", "paraherquonin biosynthesis", "paraherquonin formation", "paraherquonin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016114", "GO:0042181", "GO:1901336", "GO:1902645" ]
[]
[]
[]
[ "GO:0016114", "GO:0042181", "GO:1901336", "GO:1902645" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23591\" xsd:anyURI" ]
pg
2022-07-05T10:31:37Z
false
true
3
GO:0140876
140,876
andrastin A biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of andrastin A, a meroterpenoid that exhibits inhibitory activity against ras farnesyltransferase, suggesting that it could have promising antitumor activity.
[ "DOI:10.1016/j.tet.2013.07.029" ]
null
[ "andrastin A anabolism", "andrastin A biosynthesis", "andrastin A formation", "andrastin A synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006694", "GO:0042181", "GO:0043386", "GO:0046184", "GO:0120255" ]
[]
[]
[]
[ "GO:0006694", "GO:0042181", "GO:0043386", "GO:0046184", "GO:0120255" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23594\" xsd:anyURI" ]
pg
2022-07-05T10:42:54Z
false
true
3
GO:0140877
140,877
mevastatin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of mevastatin , also known as compactin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase.
[ "PMID:12172803", "PMID:12242508" ]
null
[ "mevastatin anabolism", "mevastatin biosynthesis", "mevastatin formation", "mevastatin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030639", "GO:0043386", "GO:1901336" ]
[]
[]
[]
[ "GO:0030639", "GO:0043386", "GO:1901336" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23597\" xsd:anyURI" ]
pg
2022-07-05T10:50:15Z
false
true
1
GO:0140878
140,878
griseofulvin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections.
[ "PMID:20534346", "PMID:23978092" ]
null
[ "griseofulvin anabolism", "griseofulvin biosynthesis", "griseofulvin formation", "griseofulvin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-7653" ]
[ "GO:0043386", "GO:0090345" ]
[]
[]
[]
[ "GO:0043386", "GO:0090345" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23598\" xsd:anyURI" ]
pg
2022-07-05T07:12:13Z
false
true
4
GO:0140879
140,879
conidiogenone biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation.
[ "PMID:30343633" ]
null
[ "conidiogenone anabolism", "conidiogenone biosynthesis", "conidiogenone formation", "conidiogenone synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016102", "GO:0042181", "GO:0043386", "GO:1902653" ]
[]
[]
[]
[ "GO:0016102", "GO:0042181", "GO:0043386", "GO:1902653" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23600\" xsd:anyURI" ]
pg
2022-07-05T11:01:27Z
false
true
8
GO:0140880
140,880
terrein biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities.
[ "PMID:24816227" ]
null
[ "terrein anabolism", "terrein biosynthesis", "terrein formation", "terrein synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043386", "GO:0046173" ]
[]
[]
[]
[ "GO:0043386", "GO:0046173" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23601\" xsd:anyURI" ]
pg
2022-07-06T06:27:15Z
false
true
4
GO:0140882
140,882
zinc export across plasma membrane
biological_process
The directed movement of zinc ions from a cell, into the extracellular region.
[ "PMID:17355957" ]
null
[ "zinc ion export from cell" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0071577", "GO:0140115" ]
[]
[]
[]
[ "GO:0071577", "GO:0140115" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23603\" xsd:anyURI" ]
pg
2022-07-08T04:56:15Z
false
true
7
GO:0140883
140,883
symbiont-mediated activation of host reticulophagy
biological_process
A process in which a symbiont initiates, promotes, or enhances the normal execution of host reticulophagy, leading to an increase in the frequency, rate or extent of reticulophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
[ "PMID:35239449" ]
null
[ "activation of host reticulophagy by virus", "induction by virus of host reticulophagy", "positive regulation by virus of host reticulophagy" ]
[ "EXACT", "NARROW", "BROAD" ]
[]
[]
[]
[ "GO:0039520" ]
[]
[]
[]
[ "GO:0039520" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23616\" xsd:anyURI" ]
pg
2022-07-08T05:08:02Z
false
true
1
GO:0140884
140,884
symbiont-mediated suppression of host type II interferon-mediated signaling pathway
biological_process
A process in which a symbiont interferes with, inhibits or disrupts a type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma.
[ "PMID:28901902" ]
null
[ "negative regulation by virus of host type II interferon-mediated signaling pathway", "suppression by virus of host type II IFN-mediated signaling pathway", "suppression by virus of host type II interferon-mediated signaling pathway", "suppression by virus of host type II interferon-mediated signalling pathwa...
[ "EXACT", "EXACT", "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0140886" ]
[]
[]
[]
[ "GO:0140886" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23647\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26686\" xsd:anyURI" ]
pg
2022-07-08T09:18:13Z
false
true
2
GO:0140885
140,885
symbiont-mediated suppression of host type III interferon-mediated signaling pathway
biological_process
A process in which a symbiont interferes with, inhibits or disrupts a type III interferon-mediated signaling in the host organism. Type III interferon is also known as interferon-lambda.
[ "PMID:32464097" ]
null
[ "negative regulation by virus of host type III interferon-mediated signaling pathway", "suppression by virus of host type III IFN-mediated signaling pathway", "suppression by virus of host type III interferon-mediated signaling pathway", "suppression by virus of host type III interferon-mediated signalling pa...
[ "EXACT", "EXACT", "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0140886" ]
[]
[]
[]
[ "GO:0140886" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23647\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26686\" xsd:anyURI" ]
pg
2022-07-08T09:20:57Z
false
true
7
GO:0140886
140,886
symbiont-mediated suppression of host interferon-mediated signaling pathway
biological_process
Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism.
[ "PMID:31266861", "PMID:33097660", "PMID:34305858" ]
null
[ "inhibition of host interferon signaling pathway by symbiont", "negative regulation by virus of host interferon-mediated signaling pathway", "suppression by symbiont of host IFN-mediated signaling pathway", "suppression by symbiont of host interferon-mediated signalling pathway", "suppression by virus of ho...
[ "RELATED", "NARROW", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0052029" ]
[]
[]
[]
[ "GO:0052029" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23647\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26686\" xsd:anyURI" ]
pg
2022-07-08T09:23:17Z
false
true
9
GO:0140887
140,887
positive regulation of nucleosome disassembly
biological_process
Any process that activates or increases the frequency, rate or extent of the controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
[ "PMID:34471130", "PMID:35308047" ]
null
[]
[]
[]
[]
[]
[ "GO:0031334", "GO:1905269" ]
[ "positively_regulates GO:0006334" ]
[ "positively_regulates" ]
[ "GO:0006334" ]
[ "GO:0006334", "GO:0031334", "GO:1905269" ]
[ "GO:0065007", "positively_regulates GO:0006334" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23229\" xsd:anyURI" ]
pg
2022-07-11T16:56:42Z
false
true
6
GO:0140888
140,888
interferon-mediated signaling pathway
biological_process
The series of molecular signals initiated by type II interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type II interferon is also known as interferon-gamma.
[ "GOC:add", "GOC:dph", "GOC:signaling", "PMID:32464097" ]
null
[ "interferon signaling pathway", "interferon-activated signaling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23647\" xsd:anyURI" ]
pg
2022-07-08T09:36:25Z
false
true
2
GO:0140890
140,890
H1 histone chaperone activity
molecular_function
A histone chaperone that carries a H1 histone.
[ "PMID:12509435" ]
null
[ "H1 histone carrier activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140713" ]
[]
[]
[]
[ "GO:0140713" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23679\" xsd:anyURI" ]
pg
2022-07-12T12:24:11Z
false
true
7
GO:0140891
140,891
tRNA-derived regulatory ncRNA processing
biological_process
A process leading to the generation of a functional small regulatory non-coding RNA derived from a tRNA.
[ "PMID:29120263" ]
null
[ "tRNA-derived small RNA processing" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0070918" ]
[]
[]
[]
[ "GO:0070918" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23081\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23735\" xsd:anyURI" ]
pg
2022-07-20T09:42:33Z
false
true
8
GO:0140892
140,892
sodium,bicarbonate:chloride antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction chloride(in) + 2 hydrogencarbonate(out) + Na+(out) = chloride(out) + 2 hydrogencarbonate(in) + Na+(in).
[ "PMID:18577713", "PMID:20389022", "PMID:8189393" ]
null
[ "sodium,hydrogencarbonate:chloride antiporter activity", "sodium-dependent chloride/bicarbonate exchanger activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "TC:2.A.31.2.4" ]
[ "GO:0015081", "GO:0140828", "GO:0140900" ]
[]
[]
[]
[ "GO:0015081", "GO:0140828", "GO:0140900" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23675\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26780\" xsd:anyURI" ]
pg
2022-07-20T11:59:45Z
false
true
6
GO:0140893
140,893
neutral amino acid, sodium:proton antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + amino acid(out) + Na+(out) = H+(out) + amino acid(in) + Na+(in).
[ "PMID:11698233", "PMID:34704597" ]
null
[ "amino acid-coupled Na+/H+ exchanger activity" ]
[ "EXACT" ]
[]
[]
[ "TC:2.A.18.6.8" ]
[ "GO:0015385" ]
[]
[]
[]
[ "GO:0015385" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23663\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24323\" xsd:anyURI" ]
pg
2022-07-20T12:11:12Z
false
true
9
GO:0140894
140,894
endolysosomal toll-like receptor signaling pathway
biological_process
The series of molecular signals initiated by a ligand binding to an endolysosomal pattern recognition receptor (PRR) of the toll-like family. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.
[ "PMID:29679565" ]
null
[ "endolysosomal pattern recognition receptor signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002753" ]
[]
[]
[]
[ "GO:0002753" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17080\" xsd:anyURI" ]
pg
2022-07-22T12:48:12Z
false
true
6
GO:0140895
140,895
cell surface toll-like receptor signaling pathway
biological_process
The series of molecular signals initiated by a ligand binding to a cell surface pattern recognition receptor (PRR) of the toll-like family.
[ "GOC:add", "GOC:ar", "ISBN:0781735149", "PMID:15199967" ]
null
[ "cell surface TLR signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002752" ]
[]
[]
[]
[ "GO:0002752" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18588\" xsd:anyURI" ]
pg
2022-07-22T13:13:17Z
false
true
7
GO:0140896
140,896
cGAS/STING signaling pathway
biological_process
The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING.
[ "PMID:27648547", "PMID:34261127", "PMID:34261128" ]
null
[]
[]
[]
[]
[]
[ "GO:0002753" ]
[]
[]
[]
[ "GO:0002753" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17080\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23981\" xsd:anyURI" ]
pg
2022-07-22T13:43:11Z
false
true
6
GO:0140897
140,897
mechanoreceptor activity
molecular_function
Combining with a mechanical force and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
[ "PMID:23907979", "PMID:34666001" ]
null
[]
[]
[]
[]
[]
[ "GO:0004888" ]
[]
[]
[]
[ "GO:0004888" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18636\" xsd:anyURI" ]
pg
2022-07-22T14:23:45Z
false
true
8
GO:0140898
140,898
CENP-A eviction from euchromatin
biological_process
A chromatin remodeling process in which CENP-A is removed from euchromatin regions to prevent neocentromere formation.
[ "PMID:27666591" ]
null
[]
[]
[]
[]
[]
[ "GO:0006338" ]
[]
[]
[]
[ "GO:0006338" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23606\" xsd:anyURI" ]
pg
2022-07-28T09:33:29Z
false
true
5
GO:0140899
140,899
plastid gene expression
biological_process
The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA i...
[ "PMID:28377785" ]
null
[]
[]
[]
[]
[]
[ "GO:0010467" ]
[ "occurs_in GO:0009536" ]
[ "occurs_in" ]
[ "GO:0009536" ]
[ "GO:0009536", "GO:0010467" ]
[ "GO:0010467", "occurs_in GO:0009536" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23083\" xsd:anyURI" ]
pg
2022-08-17T10:34:35Z
false
true
4
GO:0140900
140,900
chloride:bicarbonate antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(in) + HCO3-(out) = chloride(out) + HCO3-(in).
[ "PMID:10428871", "PMID:16606687", "RHEA:72203" ]
null
[ "bicarbonate:chloride antiporter activity", "chloride:hydrogencarbonate antiporter activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "RHEA:72203", "TC:2.A.53.2.18" ]
[ "GO:0005452", "GO:0015108", "GO:0140829" ]
[]
[]
[]
[ "GO:0005452", "GO:0015108", "GO:0140829" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:72203", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23828\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26780\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-08-17T14:47:35Z
false
true
9
GO:0140901
140,901
L-asparagine:sodium symporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-asparagine(out) + Na+(out) = L-asparagine(in) + Na+(in).
[ "PMID:21511949", "PMID:28416685" ]
null
[ "asparagine:sodium symporter activity", "sodium:asparagine symporter activity", "sodium:L-asparagine symporter activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "RHEA:71383", "TC:2.A.18.6.13" ]
[ "GO:0005295", "GO:0015182", "GO:0015655" ]
[]
[]
[]
[ "GO:0005295", "GO:0015182", "GO:0015655" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:71383", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-08-18T05:58:25Z
false
true
4
GO:0140902
140,902
L-glutamine:sodium symporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamine(out) + Na+(out) = L-glutamine(in) + Na+(in).
[ "PMID:28416685" ]
null
[ "glutamine:sodium symporter activity", "sodium:glutamine symporter activity", "sodium:L-glutamine symporter activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "TC:2.A.18.6.13" ]
[ "GO:0005295", "GO:0015186", "GO:0015655" ]
[]
[]
[]
[ "GO:0005295", "GO:0015186", "GO:0015655" ]
[]
[]
[]
[]
[]
[]
pg
2022-08-18T06:09:17Z
false
true
9
GO:0140903
140,903
histone H3R26 methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 26) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 26). This reaction is the addition of a methyl group to the arginine residue at position 26 of histone H3.
[ "PMID:17882261" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[ "histone H3R26 arginine methyltransferase activity", "histone methylase activity (H3-R26 specific)", "histone methyltransferase activity (H3-R26 specific)", "histone-arginine N-methyltransferase activity (H3-R26 specific)", "histone-H3R26 methyltransferase activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016274", "GO:0140938" ]
[]
[]
[]
[ "GO:0016274", "GO:0140938" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.1.1.319", "skos:broadMatch EC:2.1.1.320", "skos:broadMatch RHEA:48108", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23851\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https...
pg
2022-08-18T13:56:32Z
false
true
9
GO:0140904
140,904
cytoophidium organization
biological_process
A process which results in the assembly, arrangement of constituent parts, or disassembly of a cytoophidium. Cytoophidia are mesoscale, intracellular, filamentous structures that contain metabolic enzymes.
[ "PMID:25223282", "PMID:27362644" ]
null
[]
[]
[]
[]
[]
[ "GO:0097435" ]
[]
[]
[]
[ "GO:0097435" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16583\" xsd:anyURI" ]
pg
2022-08-26T08:55:10Z
false
true
8
GO:0140905
140,905
haloperoxidase activity
molecular_function
Catalysis of the reaction: R-CH + a halogen + H2O2 = R-C-halogen + H2O.
[ "PMID:28466644", "PMID:34368824" ]
null
[]
[]
[]
[]
[]
[ "GO:0004601", "GO:0140906" ]
[]
[]
[]
[ "GO:0004601", "GO:0140906" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23587\" xsd:anyURI" ]
pg
2022-08-26T15:43:50Z
false
true
7
GO:0140906
140,906
halogenase activity
molecular_function
Catalysis of the reaction: R-CH + a halogen + oxygen donor = R-C-halogen +H2O.
[ "PMID:28466644", "PMID:34368824" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-209815 \"Tyrosine is monoiodinated\"", "Reactome:R-HSA-209840 \"Two DITs combine to form thyroxine\"", "Reactome:R-HSA-209925 \"DIT and MIT combine to form triiodothyronine\"", "Reactome:R-HSA-209973 \"Tyrosine is diiodinated\"", "Reactome:R-HSA-350901 \"Iodide is organified\"" ]
[ "GO:0016705" ]
[]
[]
[]
[ "GO:0016705" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23587\" xsd:anyURI" ]
pg
2022-08-29T09:36:00Z
false
true
7
GO:0140907
140,907
flavin-dependent halogenase activity
molecular_function
Catalysis of the reaction: R-CH + a halogen + FADH2 + O2 = R-C-halogen + FAD + H2O.
[ "PMID:28466644", "PMID:34368824" ]
null
[]
[]
[]
[]
[]
[ "GO:0140906" ]
[]
[]
[]
[ "GO:0140906" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23587\" xsd:anyURI" ]
pg
2022-08-29T09:37:39Z
false
true
9
GO:0140909
140,909
kinetoplast DNA replication
biological_process
The process of doubling of the number of maxicircles and minicircles and distribution of the progeny into two daughter networks, which are identical to the parent kinetoplast DNA network.
[ "GOC:ach", "PMID:12455998", "PMID:15967722", "PMID:17462016", "PMID:8045928", "PMID:8561456" ]
null
[ "kDNA replication", "kinetoplast DNA synthesis", "replication of kinetoplast DNA" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006264" ]
[ "occurs_in GO:0020023" ]
[ "occurs_in" ]
[ "GO:0020023" ]
[ "GO:0006264", "GO:0020023" ]
[ "GO:0006260", "occurs_in GO:0020023" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24001\" xsd:anyURI" ]
pg
2022-09-16T12:15:31Z
false
true
3
GO:0140910
140,910
iRhom2/ADAM17 sheddase complex
cellular_component
A complex consisting of ADAM17 in complex with regulatory iRhoms and FERM domain containing proteins.
[ "PMID:29897336" ]
null
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16635\" xsd:anyURI" ]
pg
2022-09-16T13:39:42Z
false
true
7
GO:0140911
140,911
pore-forming activity
molecular_function
An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death.
[ "PMID:1406491", "PMID:25157079", "PMID:34387717" ]
null
[ "canonical holin activity", "holin activity", "pinholin activity", "pore forming activity" ]
[ "NARROW", "NARROW", "NARROW", "EXACT" ]
[ "GO:0034290", "GO:0034291", "GO:0034292" ]
[]
[ "TC:1.C" ]
[ "GO:0003674" ]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24007\" xsd:anyURI" ]
pg
2022-09-19T13:07:10Z
false
true
4
GO:0140912
140,912
membrane destabilizing activity
molecular_function
Binding to a membrane and increasing its permeability. This may lead to cell membrane lysis and cell content release.
[ "PMID:34496967" ]
null
[ "antimicrobial peptide" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[ "GO:0003674" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24026\" xsd:anyURI" ]
pg
2022-09-19T15:00:54Z
false
true
1
GO:0140913
140,913
viral release via disruption of host peptidoglycan cell wall
biological_process
The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.
[ "PMID:24585055", "PMID:26085488", "PMID:29495305" ]
null
[]
[]
[]
[]
[]
[ "GO:0044659" ]
[]
[]
[]
[ "GO:0044659" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24035\" xsd:anyURI" ]
pg
2022-09-21T13:56:06Z
false
true
4
GO:0140914
140,914
zinc ion import into secretory vesicle
biological_process
The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a secretory vesicle.
[ "PMID:19496757" ]
null
[]
[]
[]
[]
[]
[ "GO:0010496", "GO:0062111" ]
[]
[]
[]
[ "GO:0010496", "GO:0062111" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23879\" xsd:anyURI" ]
pg
2022-09-23T06:54:18Z
false
true
1
GO:0140915
140,915
zinc ion import into zymogen granule
biological_process
The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a zymogen granule.
[ "PMID:20133611" ]
null
[]
[]
[]
[]
[]
[ "GO:0140914" ]
[]
[]
[]
[ "GO:0140914" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23908\" xsd:anyURI" ]
pg
2022-09-23T06:57:52Z
false
true
6
GO:0140916
140,916
zinc ion import into lysosome
biological_process
The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a lysosome.
[ "PMID:25808614" ]
null
[]
[]
[]
[]
[]
[ "GO:0007041", "GO:0010496", "GO:0034486", "GO:0062111" ]
[]
[]
[]
[ "GO:0007041", "GO:0010496", "GO:0034486", "GO:0062111" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23907\" xsd:anyURI" ]
pg
2022-09-23T06:58:57Z
false
true
4
GO:0140917
140,917
zinc ion import into mitochondrion
biological_process
The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a mitochondrion.
[ "PMID:21289295" ]
null
[]
[]
[]
[]
[]
[ "GO:0010496", "GO:0062111" ]
[]
[]
[]
[ "GO:0010496", "GO:0062111" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23890\" xsd:anyURI" ]
pg
2022-09-23T07:01:26Z
false
true
8
GO:0140918
140,918
centrosomal core
cellular_component
The core region of the centrosome, a layered structure containing proteins, surrounded by the centrosomal corona. The core duplicates once per cell cycle at the G2/M transition when two outer layers form the mitotic spindle poles.
[ "PMID:28104305", "PMID:30413081" ]
null
[ "centrosome core" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005813" ]
[ "part_of" ]
[ "GO:0005813" ]
[ "GO:0005813", "GO:0110165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23933\" xsd:anyURI" ]
pg
2022-10-05T10:17:08Z
false
true
3
GO:0140919
140,919
thermomorphogenesis
biological_process
The suite of morphological and architectural changes in an organism induced by high ambient temperatures, below the heat-stress range.
[ "PMID:27250752" ]
null
[]
[]
[]
[]
[]
[ "GO:0009266", "GO:0009791" ]
[]
[]
[]
[ "GO:0009266", "GO:0009791" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24192\" xsd:anyURI" ]
pg
2022-10-17T06:30:55Z
false
true
6
GO:0140920
140,920
regulation of thermomorphogenesis
biological_process
Any process that modulates the frequency, rate or extent of thermomorphogenesis.
[ "PMID:27250752" ]
null
[]
[]
[]
[]
[]
[ "GO:0048580", "GO:0048583" ]
[ "regulates GO:0140919" ]
[ "regulates" ]
[ "GO:0140919" ]
[ "GO:0048580", "GO:0048583", "GO:0140919" ]
[ "GO:0065007", "regulates GO:0140919" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24192\" xsd:anyURI" ]
pg
2022-10-18T07:34:53Z
false
true
2
GO:0140921
140,921
negative regulation of thermomorphogenesis
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of thermomorphogenesis.
[ "PMID:27250752" ]
null
[]
[]
[]
[]
[]
[ "GO:0048581", "GO:0048585", "GO:0140920" ]
[ "negatively_regulates GO:0140919" ]
[ "negatively_regulates" ]
[ "GO:0140919" ]
[ "GO:0048581", "GO:0048585", "GO:0140919", "GO:0140920" ]
[ "GO:0065007", "negatively_regulates GO:0140919" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24192\" xsd:anyURI" ]
pg
2022-10-18T07:35:38Z
false
true
7
GO:0140922
140,922
positive regulation of thermomorphogenesis
biological_process
Any process that increases the rate, frequency or extent of thermomorphogenesis.
[ "PMID:27250752" ]
null
[]
[]
[]
[]
[]
[ "GO:0048582", "GO:0048584", "GO:0140920" ]
[ "positively_regulates GO:0140919" ]
[ "positively_regulates" ]
[ "GO:0140919" ]
[ "GO:0048582", "GO:0048584", "GO:0140919", "GO:0140920" ]
[ "GO:0065007", "positively_regulates GO:0140919" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24192\" xsd:anyURI" ]
pg
2022-10-18T07:36:04Z
false
true
9
GO:0140924
140,924
L-kynurenine transmembrane transport
biological_process
The directed movement of L-kynurenine across a membrane.
[ "PMID:35245456" ]
null
[]
[]
[]
[]
[]
[ "GO:1902475" ]
[]
[]
[]
[ "GO:1902475" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24204\" xsd:anyURI" ]
pg
2022-10-18T13:08:26Z
false
true
4
GO:0140925
140,925
L-phenylalanine import across plasma membrane
biological_process
The directed movement of L-phenylalanine from outside of a cell, across the plasma membrane and into the cytosol.
[ "PMID:11069779" ]
null
[]
[]
[]
[]
[]
[ "GO:0015695", "GO:0015801", "GO:0015823", "GO:0089718", "GO:1902475" ]
[]
[]
[]
[ "GO:0015695", "GO:0015801", "GO:0015823", "GO:0089718", "GO:1902475" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24183\" xsd:anyURI" ]
pg
2022-10-18T13:11:20Z
false
true
6
GO:0140926
140,926
L-kynurenine transmembrane transporter activity
molecular_function
Enables the transfer of L-kynurenine from one side of a membrane to the other.
[ "PMID:35245456" ]
null
[]
[]
[]
[]
[]
[ "GO:0015179" ]
[ "part_of GO:0140924" ]
[ "part_of" ]
[ "GO:0140924" ]
[ "GO:0015179", "GO:0140924" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24205\" xsd:anyURI" ]
pg
2022-10-18T13:14:59Z
false
true
4
GO:0140927
140,927
cyclic-di-GMP transmembrane transporter activity
molecular_function
Enables the transfer of cyclic-di-GMP from one side of a membrane to the other.
[ "PMID:34965418" ]
null
[]
[]
[]
[]
[]
[ "GO:0001409", "GO:0005346" ]
[]
[]
[]
[ "GO:0001409", "GO:0005346" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24013\" xsd:anyURI" ]
pg
2022-10-18T13:17:30Z
false
true
5
GO:0140928
140,928
inhibition of non-skeletal tissue mineralization
biological_process
A homeostatic process involved in the maintenance of non-mineral tissue, by preventing mineralization of non-skeletal tissue.
[ "PMID:21490328", "PMID:30030150" ]
null
[ "inhibition of ectopic tissue mineralization" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0001894" ]
[]
[]
[]
[ "GO:0001894" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24228\" xsd:anyURI" ]
pg
2022-10-20T13:05:32Z
false
true
5
GO:0140929
140,929
mannose:sodium symporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-mannose(out) + Na+(out) = D-mannose(in) + Na+(in).
[ "PMID:22212718", "PMID:23451068", "PMID:24573086" ]
null
[]
[]
[]
[]
[]
[ "GO:0005402", "GO:0015370", "GO:0015578" ]
[]
[]
[]
[ "GO:0005402", "GO:0015370", "GO:0015578" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24185\" xsd:anyURI" ]
pg
2022-10-20T14:15:09Z
false
true
6
GO:0140930
140,930
fructose:sodium symporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-fructose(out) + Na+(out) = D-fructose(in) + Na+(in).
[ "PMID:22212718", "PMID:23451068" ]
null
[]
[]
[]
[]
[]
[ "GO:0005353", "GO:0005402", "GO:0015370" ]
[]
[]
[]
[ "GO:0005353", "GO:0005402", "GO:0015370" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24185\" xsd:anyURI" ]
pg
2022-10-20T14:15:18Z
false
true
9
GO:0140931
140,931
neutral L-amino acid:sodium:chloride symporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral L-amino acid(out) + Na+(out) + Cl-(out) = neutral L-amino acid(in) + Na+(in)+ Cl-(in).
[ "PMID:19478081" ]
null
[ "neutral amino acid:sodium:chloride symporter activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0005283", "GO:0015175", "GO:0015378" ]
[]
[]
[]
[ "GO:0005283", "GO:0015175", "GO:0015378" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24162\" xsd:anyURI" ]
pg
2022-10-21T11:40:45Z
false
true
5
GO:0140932
140,932
5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity
molecular_function
Catalysis of the reaction: a 5'-end (N2,N2,N7-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H+ + N7-methyl-GMP. Can also use (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA as a substrate.
[ "PMID:24742626", "PMID:32723815" ]
null
[ "m(7)GpppN m(7)GMP phosphohydrolase activity", "m(7)GpppX diphosphatase activity", "m(7)GpppX pyrophosphatase activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "EC:3.6.1.59", "RHEA:65384", "RHEA:65388" ]
[ "GO:0016462" ]
[]
[]
[]
[ "GO:0016462" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.6.1.59", "skos:narrowMatch RHEA:65384", "skos:narrowMatch RHEA:65388" ]
pg
2022-10-24T15:37:32Z
false
true
3
GO:0140933
140,933
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
molecular_function
Catalysis of the reaction: a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.
[ "PMID:18820299", "PMID:29483298" ]
null
[ "m(7)GpppN-mRNA hydrolase activity" ]
[ "EXACT" ]
[]
[]
[ "EC:3.6.1.62", "RHEA:37371", "RHEA:67484" ]
[ "GO:0016462" ]
[]
[]
[]
[ "GO:0016462" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.6.1.62", "skos:exactMatch RHEA:67484", "skos:narrowMatch RHEA:37371", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23290\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
pg
2022-10-24T15:48:42Z
false
true
5
GO:0140934
140,934
histone deubiquitinase activity
molecular_function
A deubiquitinase that cleaves ubiquitin from a histone protein to which it is conjugated.
[ "PMID:18206972", "PMID:18226187" ]
null
[ "histone deubiquitination" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0101005", "GO:0140993" ]
[]
[]
[]
[ "GO:0101005", "GO:0140993" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22769\" xsd:anyURI" ]
pg
2022-11-01T07:39:52Z
false
true
2
GO:0140935
140,935
histone H2B conserved C-terminal lysine deubiquitinase activity
molecular_function
A histone deubiquitinase that cleaves ubiquitin from the conserved C-terminal lysine residue of a histone H2B protein to which it is conjugated. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, and K120 in mammals.
[ "PMID:15657442" ]
null
[ "histone conserved C-terminal lysine deubiquitination" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0140936" ]
[]
[]
[]
[ "GO:0140936" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22769\" xsd:anyURI" ]
pg
2022-11-01T07:46:50Z
false
true
6