LiteFold/GO · Datasets at Hugging Face

GO:0005461

5,461

UDP-glucuronate transmembrane transporter activity

molecular_function

Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.

[ "GOC:ai", "GOC:mtg_transport", "ISBN:0815340729" ]

null

[ "UDP-glucuronic acid transmembrane transporter activity" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-174368 \"SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen\"", "Reactome:R-HSA-5603297 \"Defective SLC35D1 does not transport UDP-GlcA, UDPGlcNAc\"", "Reactome:R-HSA-9912889 \"SLC35D2 exchanges UDP-GlcA for UMP\"" ]

[ "GO:0015165", "GO:0046943" ]

[ "part_of GO:0015787" ]

[ "part_of" ]

[ "GO:0015787" ]

[ "GO:0015165", "GO:0015787", "GO:0046943" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29382\" xsd:anyURI" ]

null

false

true

9

GO:0005462

5,462

UDP-N-acetylglucosamine transmembrane transporter activity

molecular_function

Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.

[ "GOC:ai", "GOC:mtg_transport", "ISBN:0815340729" ]

null

[]

[ "Reactome:R-HSA-5653622 \"Defective SLC35A3 does not exchange UDP-GlcNAc for UMP\"", "Reactome:R-HSA-741450 \"SLC35A3 exchanges UDP-GlcNAc for UMP\"", "Reactome:R-HSA-742354 \"SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen\"" ]

[ "GO:0015165" ]

[ "part_of GO:1990569" ]

[ "part_of" ]

[ "GO:1990569" ]

[ "GO:0015165", "GO:1990569" ]

[]

null

false

true

8

GO:0005463

5,463

UDP-N-acetylgalactosamine transmembrane transporter activity

molecular_function

Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.

[ "GOC:ai", "GOC:mtg_transport", "ISBN:0815340729" ]

null

[]

[ "GO:0015165" ]

[ "part_of GO:0015789" ]

[ "part_of" ]

[ "GO:0015789" ]

[ "GO:0015165", "GO:0015789" ]

[]

null

false

true

7

GO:0005464

5,464

UDP-xylose transmembrane transporter activity

molecular_function

Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.

[ "GOC:ai" ]

null

[]

[ "Reactome:R-HSA-742373 \"SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen\"" ]

[ "GO:0015165" ]

[ "part_of GO:0015790" ]

[ "part_of" ]

[ "GO:0015790" ]

[ "GO:0015165", "GO:0015790" ]

[]

null

false

true

3

GO:0005468

5,468

obsolete small-molecule carrier or transporter

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because it does not provide a useful functional classification.

[ "small-molecule carrier or transporter" ]

[ "EXACT" ]

[ "GO:0005453", "GO:0005454" ]

[]

[ "GO:0005215" ]

[]

null

true

4

GO:0005469

5,469

succinate:fumarate antiporter activity

molecular_function

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out).

[ "TC:2.A.29.13.1" ]

null

[]

[ "RHEA:29323" ]

[ "GO:0015138", "GO:0015141", "GO:0015297" ]

[]

[ "GO:0015138", "GO:0015141", "GO:0015297" ]

[]

[ "skos:exactMatch RHEA:29323", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27278\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

8

GO:0005471

5,471

ATP:ADP antiporter activity

molecular_function

Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out).

[ "TC:2.A.29.1.1" ]

null

[ "adenine nucleotide translocase", "ADP/ATP carrier protein", "ADP/ATP translocase", "ATP/ADP exchange", "ATP/ADP exchanger" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[ "GO:0005349" ]

[]

[ "RHEA:34999" ]

[ "GO:0005347", "GO:0015217", "GO:0015297" ]

[]

[ "GO:0005347", "GO:0015217", "GO:0015297" ]

[]

[ "skos:exactMatch RHEA:34999", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27278\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

3

GO:0005476

5,476

carnitine:O-acyl-L-carnitine antiporter activity

molecular_function

Catalysis of the reaction: carnitine (mitochondrial) + O-acyl-L-carnitine (cytoplasm) = carnitine (cytoplasm) + O-acyl-L-carnitine (mitochondrial).

[ "PMID:9032458" ]

null

[ "carnitine/acyl carnitine carrier activity", "carnitine:acyl carnitine carrier activity", "fatty acyl carnitine carrier" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-200424 \"Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane\"" ]

[ "GO:0015226", "GO:0015227", "GO:0015297" ]

[]

[ "GO:0015226", "GO:0015227", "GO:0015297" ]

[]

null

false

true

2

GO:0005479

5,479

obsolete vacuolar assembly

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because it represents a biological process and not a molecular function.

[ "vacuolar assembly" ]

[ "EXACT" ]

[]

[ "GO:0007033" ]

[]

null

true

5

GO:0005481

5,481

obsolete vesicle fusion

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because it represents a biological process and not a molecular function.

[ "vesicle fusion" ]

[ "EXACT" ]

[]

[ "GO:0006906", "GO:0016189", "GO:0016192", "GO:0019817" ]

[]

null

true

6

GO:0005482

5,482

obsolete vesicle targeting

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because it represents a biological process and not a molecular function.

[ "vesicle targeting" ]

[ "EXACT" ]

[]

[ "GO:0006903", "GO:0016080" ]

[]

null

true

6

GO:0005483

5,483

soluble NSF attachment protein activity

molecular_function

Binding to both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.

[ "GOC:mah", "PMID:14570579", "PMID:15556857" ]

null

[ "SNAP" ]

[ "EXACT" ]

[]

[ "GO:0030674" ]

[]

[ "GO:0030674" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16807\" xsd:anyURI" ]

null

false

true

4

GO:0005484

5,484

SNAP receptor activity

molecular_function

Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.

[ "GOC:mah", "PMID:14570579" ]

null

[ "Q-SNARE activity", "R-SNARE activity", "SNAP-25", "SNARE", "t-SNARE activity", "v-SNARE activity" ]

[ "NARROW", "NARROW", "NARROW", "EXACT", "NARROW", "NARROW" ]

[ "GO:0005485", "GO:0005486" ]

[ "goslim_chembl" ]

[]

[ "GO:0030674" ]

[ "part_of GO:0061025", "part_of GO:0140522" ]

[ "part_of", "part_of" ]

[ "GO:0061025", "GO:0140522" ]

[ "GO:0030674", "GO:0061025", "GO:0140522" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31564\" xsd:anyURI" ]

null

false

true

8

GO:0005488

5,488

binding

molecular_function

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

[ "GOC:ceb", "GOC:mah", "ISBN:0198506732" ]

null

[ "ligand" ]

[ "NARROW" ]

[]

[ "goslim_pir", "goslim_plant" ]

[ "Wikipedia:Binding_(molecular)" ]

[ "GO:0003674" ]

[]

[ "GO:0003674" ]

[]

null

false

true

5

GO:0005489

5,489

obsolete electron transporter activity

molecular_function

OBSOLETE. Enables the directed movement of electrons into, out of, within or between cells.

[ "GOC:ai" ]

This term was made obsolete because the activity described by the definition does not exist.

[ "class I cytochrome c", "class II cytochrome c", "class IIa cytochrome c", "class IIb cytochrome c", "class III cytochrome c", "class IV cytochrome c", "cytochrome b", "cytochrome b5", "cytochrome c3 (tetraheme)", "cytochrome c554", "cytochrome c7 (triheme)", "cytochrome d", "diheme class I ...

[ "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "EXACT", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:0009055" ]

[]

null

true

1

GO:0005490

5,490

obsolete cytochrome P450

molecular_function

OBSOLETE. A cytochrome b that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes:typically monooxygenases acting on lipophilic substrates.

[ "ISBN:0198547684" ]

This term was made obsolete because its definition was changed and because it represents a gene product.

[ "cytochrome P450" ]

[ "EXACT" ]

[]

null

true

5

GO:0005496

5,496

steroid binding

molecular_function

Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.

[ "GOC:jl", "ISBN:0198506732" ]

null

[]

[ "goslim_pir" ]

[]

[ "GO:0008289" ]

[]

[ "GO:0008289" ]

[]

null

false

true

7

GO:0005497

5,497

androgen binding

molecular_function

Binding to an androgen, a male sex hormone.

[ "GOC:jl" ]

null

[]

[ "GO:0042562" ]

[]

[ "GO:0042562" ]

[]

null

false

true

1

GO:0005499

5,499

vitamin D binding

molecular_function

Binding to vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).

[ "GOC:mah", "ISBN:0471331309" ]

null

[ "calciferol binding", "cholecalciferol binding", "ergocalciferol binding" ]

[ "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0005496", "GO:0019842" ]

[]

[ "GO:0005496", "GO:0019842" ]

[]

null

false

true

1

GO:0005500

5,500

juvenile hormone binding

molecular_function

Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.

[ "GOC:jl", "ISBN:0198506732" ]

null

[]

[ "GO:0019840", "GO:0042562" ]

[]

[ "GO:0019840", "GO:0042562" ]

[]

null

false

true

8

GO:0005501

5,501

retinoid binding

molecular_function

Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.

[ "GOC:jl", "ISBN:0198506732" ]

null

[]

[ "Reactome:R-HSA-2454113 \"RBP3 transports 11cRAL to rod photoreceptor outer segment\"", "Reactome:R-HSA-2464809 \"RBP3 regulates the transport of atROL from ROS to RPE\"", "Reactome:R-HSA-2465934 \"11cROL translocates from Muller cells to cone photoreceptor cells\"", "Reactome:R-HSA-2465938 \"RBP3 regulates a...

[ "GO:0019840" ]

[]

[ "GO:0019840" ]

[]

null

false

true

2

GO:0005502

5,502

11-cis retinal binding

molecular_function

Binding to 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.

[ "PMID:24403072" ]

null

[ "11-cis retinaldehyde binding", "11-cis-retinal binding", "vitamin A binding" ]

[ "EXACT", "NARROW", "BROAD" ]

[]

[ "GO:0016918" ]

[]

[ "GO:0016918" ]

[]

null

false

true

8

GO:0005503

5,503

all-trans retinal binding

molecular_function

Binding to all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.

[ "GOC:curators" ]

null

[ "all-trans retinaldehyde binding", "trans retinal binding", "visual yellow binding", "vitamin A binding", "xanthopsin" ]

[ "EXACT", "EXACT", "EXACT", "BROAD", "RELATED" ]

[]

[ "GO:0016918" ]

[]

[ "GO:0016918" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14750\" xsd:anyURI" ]

null

false

true

1

GO:0005504

5,504

fatty acid binding

molecular_function

Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.

[ "ISBN:0198506732" ]

null

[]

[ "GO:0008289", "GO:0033293" ]

[]

[ "GO:0008289", "GO:0033293" ]

[]

null

false

true

1

GO:0005505

5,505

obsolete heavy metal binding

molecular_function

OBSOLETE. Interacting selectively with a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.

[ "GOC:kd", "GOC:mah" ]

This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).

[ "heavy metal binding" ]

[ "EXACT" ]

[]

[ "GO:0046872" ]

[]

null

true

1

GO:0005507

5,507

copper ion binding

molecular_function

Binding to a copper (Cu) ion.

[ "GOC:ai" ]

null

[ "copper binding", "copper/cadmium binding" ]

[ "EXACT", "BROAD" ]

[]

[ "GO:0046914" ]

[]

[ "GO:0046914" ]

[]

null

false

true

5

GO:0005508

5,508

obsolete copper/cadmium binding

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

This term was made obsolete because it represents a composite function.

[ "copper/cadmium binding" ]

[ "EXACT" ]

[]

[ "GO:0005507", "GO:0046870" ]

[]

null

true

6

GO:0005509

5,509

calcium ion binding

molecular_function

Binding to a calcium ion (Ca2+).

[ "GOC:ai" ]

null

[ "calcium ion storage activity" ]

[ "RELATED" ]

[]

[ "GO:0046872" ]

[]

[ "GO:0046872" ]

[]

null

false

true

8

GO:0005513

5,513

detection of calcium ion

biological_process

The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal.

[ "GOC:pg" ]

null

[ "Ca2+ ion detection", "calcium ion detection", "calcium ion sensing", "detection of Ca2+ ion" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0009593", "GO:0051592" ]

[]

[ "GO:0009593", "GO:0051592" ]

[]

null

false

true

5

GO:0005514

5,514

obsolete calcium ion storage activity

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

This term was made obsolete because it represents a biological process.

[ "calcium ion storage activity" ]

[ "EXACT" ]

[]

[ "GO:0005509" ]

[]

null

true

3

GO:0005515

5,515

protein binding

molecular_function

Binding to a protein.

[ "GOC:curators" ]

null

[ "glycoprotein binding", "protein amino acid binding" ]

[ "NARROW", "EXACT" ]

[ "GO:0001948", "GO:0045308" ]

[ "goslim_candida", "goslim_chembl", "goslim_euk_cellular_processes_ribbon", "goslim_metagenomics", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_prokaryote_ribbon" ]

[ "Reactome:R-HSA-9866132 \"Intermediate II binds CYC1, UQCRC1, UQCRC2, UQCRH\"" ]

[ "GO:0005488" ]

[]

[ "GO:0005488" ]

[]

null

false

true

5

GO:0005516

5,516

calmodulin binding

molecular_function

Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

[ "GOC:krc" ]

null

[]

[ "goslim_chembl" ]

[ "Reactome:R-HSA-202110 \"eNOS:Caveolin-1 complex binds to CaM\"" ]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

null

false

true

5

GO:0005517

5,517

obsolete calmodulin inhibitor activity

molecular_function

OBSOLETE. This term was not defined before being made obsolete.

[ "GOC:tb" ]

This term was made obsolete because it refers to a non-existent molecular function term, 'calmodulin activity'.

[ "calmodulin inhibitor activity" ]

[ "EXACT" ]

[]

[ "GO:0005516" ]

[]

null

true

7

GO:0005518

5,518

collagen binding

molecular_function

Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).

[ "GOC:ai", "ISBN:0198506732" ]

null

[]

[ "GO:0044877" ]

[]

[ "GO:0044877" ]

[]

null

false

true

2

GO:0005519

5,519

cytoskeletal regulatory protein binding

molecular_function

Binding to a protein involved in modulating the reorganization of the cytoskeleton.

[ "GOC:curators", "PMID:15163540" ]

null

[]

[ "GO:0008092" ]

[]

[ "GO:0008092" ]

[]

null

false

true

7

GO:0005521

5,521

lamin binding

molecular_function

Binding to lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.

[ "GOC:jl", "ISBN:0198506732" ]

null

[ "lamin/chromatin binding" ]

[ "BROAD" ]

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

null

false

true

8

GO:0005522

5,522

profilin binding

molecular_function

Binding to profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.

[ "ISBN:0721662544" ]

null

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

null

false

true

1

GO:0005523

5,523

tropomyosin binding

molecular_function

Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.

[ "GOC:curators", "ISBN:0815316194" ]

null

[]

[ "GO:0008092" ]

[]

[ "GO:0008092" ]

[]

null

false

true

2

GO:0005527

5,527

macrolide binding

molecular_function

Binding to a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.

[ "GOC:jl", "ISBN:0198506732" ]

null

[]

[ "GO:0005488" ]

[]

[ "GO:0005488" ]

[]

null

false

true

6

GO:0005528

5,528

FK506 binding

molecular_function

Binding to a 23-membered macrolide lactone FK506.

[ "GOC:jl" ]

null

[ "FK506-sensitive peptidyl-prolyl cis-trans isomerase" ]

[ "RELATED" ]

[]

[ "GO:0005527" ]

[]

[ "GO:0005527" ]

[]

null

false

true

5

GO:0005530

5,530

obsolete lectin

molecular_function

OBSOLETE. Lectins are proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or ot...

[ "GOC:curators" ]

This term was made obsolete because it refers to a class of gene products.

[ "lectin" ]

[ "EXACT" ]

[]

[ "GO:0007157", "GO:0030246" ]

[]

null

true

4

GO:0005531

5,531

obsolete galactose binding lectin

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

This term was made obsolete because it refers to a class of gene products.

[ "galactose binding lectin" ]

[ "EXACT" ]

[]

[ "GO:0005534", "GO:0007157" ]

[]

null

true

8

GO:0005532

5,532

obsolete mannose binding lectin

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

This term was made obsolete because it refers to a class of gene products.

[ "mannose binding lectin", "mannose receptor" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0005537", "GO:0007157" ]

[]

null

true

5

GO:0005533

5,533

obsolete N-acetylgalactosamine lectin

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

This term was made obsolete because it refers to a class of gene products.

[ "N-acetylgalactosamine lectin" ]

[ "EXACT" ]

[]

[ "GO:0007157", "GO:0046871" ]

[]

null

true

9

GO:0005534

5,534

galactose binding

molecular_function

Binding to aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.

[ "GOC:jl", "ISBN:0198506732" ]

null

[ "galactose binding lectin" ]

[ "RELATED" ]

[]

[ "GO:0048029" ]

[]

[ "GO:0048029" ]

[]

null

false

true

9

GO:0005536

5,536

D-glucose binding

molecular_function

Binding to D-enantiomers of glucose.

[ "GOC:jl" ]

null

[ "glucose binding" ]

[ "BROAD" ]

[]

[ "GO:0048029" ]

[]

[ "GO:0048029" ]

[]

null

false

true

5

GO:0005537

5,537

D-mannose binding

molecular_function

Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.

[ "GOC:jl", "ISBN:0192800981" ]

null

[ "mannose binding", "mannose binding lectin" ]

[ "BROAD", "RELATED" ]

[]

[ "goslim_chembl" ]

[ "Reactome:R-HSA-947991 \"Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi\"" ]

[ "GO:0048029" ]

[]

[ "GO:0048029" ]

[]

null

false

true

3

GO:0005539

5,539

glycosaminoglycan binding

molecular_function

Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.

[ "GOC:jl", "ISBN:0198506732" ]

null

[]

[ "goslim_chembl" ]

[]

[ "GO:0097367" ]

[]

[ "GO:0097367" ]

[]

null

false

true

5

GO:0005540

5,540

hyaluronic acid binding

molecular_function

Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.

[ "GOC:jl" ]

null

[ "hyaluronan binding" ]

[ "EXACT" ]

[]

[ "GO:0031406" ]

[]

[ "GO:0031406" ]

[]

null

false

true

7

GO:0005541

5,541

obsolete acyl-CoA or acyl binding

molecular_function

OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid.

[ "GOC:jl", "ISBN:0198506732" ]

This term was made obsolete because it was replaced by more appropriate terms.

[ "acyl-CoA or acyl binding" ]

[ "EXACT" ]

[]

[ "GO:0000035", "GO:0000062" ]

[]

null

true

2

GO:0005542

5,542

folic acid binding

molecular_function

Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.

[ "GOC:jl", "ISBN:0198506732" ]

null

[ "folate binding", "vitamin B9 binding", "vitamin M binding" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0019842", "GO:0031406", "GO:0072341", "GO:1901363" ]

[]

[ "GO:0019842", "GO:0031406", "GO:0072341", "GO:1901363" ]

[]

null

false

true

2

GO:0005543

5,543

phospholipid binding

molecular_function

Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.

[ "ISBN:0198506732" ]

null

[]

[ "GO:0008289" ]

[]

[ "GO:0008289" ]

[]

null

false

true

6

GO:0005544

5,544

calcium-dependent phospholipid binding

molecular_function

Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.

[ "GOC:jl" ]

null

[]

[ "GO:0005543" ]

[]

[ "GO:0005543" ]

[]

null

false

true

4

GO:0005546

5,546

phosphatidylinositol-4,5-bisphosphate binding

molecular_function

Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.

[ "GOC:bf", "GOC:jl" ]

null

[ "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding", "phosphatidylinositol 4,5-bisphosphate binding", "PIP2 binding", "PtdIns(4,5)P2 binding" ]

[ "EXACT", "EXACT", "BROAD", "EXACT" ]

[]

[ "GO:1901981", "GO:1902936" ]

[]

[ "GO:1901981", "GO:1902936" ]

[]

null

false

true

2

GO:0005547

5,547

phosphatidylinositol-3,4,5-trisphosphate binding

molecular_function

Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.

[ "GOC:bf", "GOC:jl" ]

null

[ "PIP3 binding" ]

[ "EXACT" ]

[]

[ "GO:0043168", "GO:1901981" ]

[]

[ "GO:0043168", "GO:1901981" ]

[]

null

false

true

8

GO:0005548

5,548

obsolete phospholipid transporter activity

molecular_function

OBSOLETE. Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.

[ "GOC:ai", "ISBN:0198506732" ]

This term was obsoleted because it refers to the substrate rather than to the transport mechanism as a primary classification.

[]

[ "GO:0008497" ]

[]

[ "Reactome:R-HSA-216757 \"4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane\"", "Reactome:R-HSA-382553 \"ABCA7:Apo1A-mediated phospholipid efflux\"", "Reactome:R-HSA-5678706 \"ABCB4 transports PC from plasma membrane to extracellular region\"", "Reactome:R-HSA-567874...

[]

[ "GO:0120014", "GO:0170055" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31454\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31460\" xsd:anyURI" ]

null

true

6

GO:0005550

5,550

pheromone binding

molecular_function

Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.

[ "GOC:ai" ]

null

[]

[ "GO:0005549" ]

[]

[ "GO:0005549" ]

[]

null

false

true

4

GO:0005551

5,551

obsolete ubiquitin

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because it represents a gene product.

[]

[ "GO:0016567", "GO:0031386" ]

[]

null

true

4

GO:0005553

5,553

obsolete ubiquitin-ribosomal protein fusion protein

molecular_function

OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein.

[ "ISBN:0198506732" ]

This term was made obsolete because it describes a gene product.

[ "ubiquitin-ribosomal protein fusion protein" ]

[ "EXACT" ]

[]

null

true

7

GO:0005555

5,555

obsolete blood group antigen

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.

[ "blood group antigen" ]

[ "EXACT" ]

[]

null

true

7

GO:0005557

5,557

obsolete lymphocyte antigen

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.

[ "lymphocyte antigen" ]

[ "EXACT" ]

[]

null

true

6

GO:0005558

5,558

obsolete minor histocompatibility antigen

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.

[ "minor histocompatibility antigen" ]

[ "EXACT" ]

[]

null

true

6

GO:0005559

5,559

obsolete ribozyme

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "ribozyme" ]

[ "EXACT" ]

[]

null

true

7

GO:0005561

5,561

obsolete nucleic acid

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "nucleic acid" ]

[ "EXACT" ]

[]

null

true

4

GO:0005562

5,562

obsolete RNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "RNA" ]

[ "EXACT" ]

[]

null

true

5

GO:0005563

5,563

obsolete transfer RNA

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a gene product.

[ "transfer RNA" ]

[ "EXACT" ]

[]

[ "GO:0030533" ]

[]

null

true

6

GO:0005564

5,564

obsolete cytosolic tRNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "cytosolic tRNA" ]

[ "EXACT" ]

[]

null

true

3

GO:0005565

5,565

obsolete mitochondrial tRNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "mitochondrial tRNA" ]

[ "EXACT" ]

[]

null

true

4

GO:0005566

5,566

obsolete ribosomal RNA

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a gene product.

[ "ribosomal RNA" ]

[ "EXACT" ]

[]

[ "GO:0003735", "GO:0005840" ]

[]

null

true

4

GO:0005567

5,567

obsolete cytosolic ribosomal RNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "cytosolic ribosomal RNA" ]

[ "EXACT" ]

[]

null

true

3

GO:0005568

5,568

obsolete mitochondrial rRNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "mitochondrial rRNA" ]

[ "EXACT" ]

[]

null

true

6

GO:0005569

5,569

obsolete small nucleolar RNA

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents gene products.

[ "small nucleolar RNA" ]

[ "EXACT" ]

[]

[ "GO:0030555" ]

[]

null

true

9

GO:0005570

5,570

obsolete small nuclear RNA

molecular_function

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents gene products.

[ "small nuclear RNA" ]

[ "EXACT" ]

[]

[ "GO:0000375", "GO:0017069" ]

[]

null

true

7

GO:0005571

5,571

obsolete untranslated RNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "untranslated RNA" ]

[ "EXACT" ]

[]

null

true

1

GO:0005572

5,572

obsolete RNA polymerase II transcribed untranslated RNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "RNA polymerase II transcribed untranslated RNA" ]

[ "EXACT" ]

[]

null

true

8

GO:0005573

5,573

obsolete telomerase RNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:krc" ]

This term was made obsolete because it represents a gene product.

[ "telomerase RNA" ]

[ "EXACT" ]

[]

[ "GO:0000332" ]

[]

null

true

6

GO:0005574

5,574

obsolete DNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.

[ "DNA" ]

[ "EXACT" ]

[]

null

true

7

GO:0005575

5,575

cellular_component

A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-encl...

[ "GOC:pdt" ]

Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotate...

[ "cell or subcellular entity", "cellular component", "subcellular entity" ]

[ "EXACT", "EXACT", "RELATED" ]

[ "GO:0008372" ]

[ "goslim_candida", "goslim_chembl", "goslim_metagenomics", "goslim_pir", "goslim_plant", "goslim_yeast" ]

[ "NIF_Subcellular:sao1337158144" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17729\" xsd:anyURI" ]

null

false

true

8

GO:0005576

5,576

extracellular region

cellular_component

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

[ "GOC:curators" ]

Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular sp...

[ "extracellular" ]

[ "EXACT" ]

[]

[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_flybase_ribbon", "goslim_generic", "goslim_metagenomics", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_prokaryote", "goslim_prokaryote_ribbo...

[ "Wikipedia:Extracellular" ]

[ "GO:0110165" ]

[]

[ "GO:0110165" ]

[]

null

false

true

1

GO:0005577

5,577

fibrinogen complex

cellular_component

A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked togethe...

[ "ISBN:0198547684" ]

null

[ "fibrinogen", "fibrinogen alpha chain", "fibrinogen beta chain", "fibrinogen gamma chain" ]

[ "EXACT", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0140392" ]

[]

[ "GO:0140392" ]

[]

null

false

true

3

GO:0005579

5,579

membrane attack complex

cellular_component

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

[ "GOC:add", "ISBN:0198547684", "ISBN:068340007X", "ISBN:0781735149" ]

null

[ "MAC", "membrane attack complex protein alphaM chain", "membrane attack complex protein beta2 chain", "TCC", "terminal complement complex" ]

[ "EXACT", "NARROW", "NARROW", "EXACT", "EXACT" ]

[]

[ "Wikipedia:Complement_membrane_attack_complex" ]

[ "GO:0046930", "GO:0098797" ]

[]

[ "GO:0046930", "GO:0098797" ]

[]

null

false

true

8

GO:0005581

5,581

collagen trimer

cellular_component

A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.

[ "GOC:dos", "GOC:mah", "PMID:19693541", "PMID:21421911" ]

null

[]

[ "Wikipedia:Collagen" ]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

null

false

true

5

GO:0005582

5,582

collagen type XV trimer

cellular_component

A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils.

[ "PMID:11158616", "PMID:11937714", "PMID:21421911" ]

null

[]

[ "GO:0140156" ]

[]

[ "GO:0140156" ]

[]

null

false

true

1

GO:0005583

5,583

fibrillar collagen trimer

cellular_component

Any triple helical collagen trimer that forms fibrils.

[ "PMID:21421911" ]

null

[]

[ "GO:0005581", "GO:0140392" ]

[ "part_of GO:0098643" ]

[ "part_of" ]

[ "GO:0098643" ]

[ "GO:0005581", "GO:0098643", "GO:0140392" ]

[ "GO:0005581", "part_of GO:0098643" ]

[]

[ "GO:0030936" ]

[]

null

false

true

7

GO:0005585

5,585

collagen type II trimer

cellular_component

A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils.

[ "PMID:21421911" ]

null

[]

[ "Wikipedia:Collagen_type_II" ]

[ "GO:0005583" ]

[]

[ "GO:0005583" ]

[]

null

false

true

1

GO:0005586

5,586

collagen type III trimer

cellular_component

A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.

[ "PMID:21421911" ]

null

[]

[ "GO:0005583" ]

[]

[ "GO:0005583" ]

[]

null

false

true

6

GO:0005587

5,587

collagen type IV trimer

cellular_component

A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.

[ "PMID:19693541", "PMID:21421911" ]

null

[]

[ "Wikipedia:Collagen_type_IV" ]

[ "GO:0098642" ]

[ "part_of GO:0140154" ]

[ "part_of" ]

[ "GO:0140154" ]

[ "GO:0098642", "GO:0140154" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30148\" xsd:anyURI" ]

null

false

true

6

GO:0005588

5,588

collagen type V trimer

cellular_component

A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils.

[ "PMID:21421911" ]

null

[]

[ "GO:0005583" ]

[]

[ "GO:0005583" ]

[]

null

false

true

6

GO:0005589

5,589

collagen type VI trimer

cellular_component

A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils.

[ "PMID:19693541", "PMID:21421911" ]

null

[]

[ "GO:0140158", "GO:0140392" ]

[ "part_of GO:0098647" ]

[ "part_of" ]

[ "GO:0098647" ]

[ "GO:0098647", "GO:0140158", "GO:0140392" ]

[]

null

false

true

1

GO:0005590

5,590

collagen type VII trimer

cellular_component

A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin.

[ "PMID:19693541" ]

null

[]

[ "GO:0140158", "GO:0140392" ]

[ "part_of GO:0098648" ]

[ "part_of" ]

[ "GO:0098648" ]

[ "GO:0098648", "GO:0140158", "GO:0140392" ]

[]

null

false

true

8

GO:0005591

5,591

collagen type VIII trimer

cellular_component

A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.

[ "PMID:21421911" ]

null

[]

[ "GO:0098642" ]

[ "part_of GO:0098646" ]

[ "part_of" ]

[ "GO:0098646" ]

[ "GO:0098642", "GO:0098646" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30148\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31070\" xsd:anyURI" ]

null

false

true

4

GO:0005592

5,592

collagen type XI trimer

cellular_component

A collagen heterotrimer containing type XI and type II alpha chains in alpha1(XI) alpha2(XI) alpha1(II) trimers; type XI collagen triple helices associate to form fibrils.

[ "PMID:7642541" ]

null

[]

[ "GO:0005583" ]

[]

[ "GO:0005583" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30122\" xsd:anyURI" ]

null

false

true

3

GO:0005593

5,593

FACIT collagen trimer

cellular_component

A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences.

[ "PMID:21421911" ]

The acronym FACIT stands for fibril-associated collagen with interrupted triple helix.

[]

[ "Wikipedia:FACIT_collagen" ]

[ "GO:0005581", "GO:0140392" ]

[ "part_of GO:0140153" ]

[ "part_of" ]

[ "GO:0140153" ]

[ "GO:0005581", "GO:0140153", "GO:0140392" ]

[]

null

false

true

7

GO:0005594

5,594

collagen type IX trimer

cellular_component

A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils.

[ "PMID:21421911" ]

null

[]

[ "GO:0005593" ]

[]

[ "GO:0005593" ]

[]

null

false

true

6

GO:0005595

5,595

collagen type XII trimer

cellular_component

A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.

[ "PMID:21421911" ]

null

[]

[ "GO:0005593" ]

[]

[ "GO:0005593" ]

[]

null

false

true

9

GO:0005596

5,596

collagen type XIV trimer

cellular_component

A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.

[ "PMID:21421911" ]

null

[]

[ "GO:0005593" ]

[]

[ "GO:0005593" ]

[]

null

false

true

7

GO:0005597

5,597

collagen type XVI trimer

cellular_component

A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.

[ "PMID:12782140" ]

null

[]

[ "GO:0005593" ]

[]

[ "GO:0005593" ]

[]

null

false

true

8

GO:0005598

5,598

obsolete short-chain collagen trimer

cellular_component

OBSOLETE. Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils.

[ "ISBN:0198599587" ]

This term was obsoleted because it was an unnecessary grouping term.

[]

[ "GO:0005591", "GO:0005599" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29485\" xsd:anyURI" ]

null

true

1

GO:0005599

5,599

collagen type X trimer

cellular_component

A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).

[ "PMID:21421911" ]

Collagen X trimers have been observed to form hexagonal lattices in vitro, but in vivo they have been found in a fibril associated form (PMID:19693541).

[]

[ "GO:0098642" ]

[ "part_of GO:0098646" ]

[ "part_of" ]

[ "GO:0098646" ]

[ "GO:0098642", "GO:0098646" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29415\" xsd:anyURI" ]

null

false

true

8

GO:0005601

5,601

classical-complement-pathway C3/C5 convertase complex

cellular_component

A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.

[ "GOC:mah" ]

null

[]

[ "GO:0140392", "GO:1902494" ]

[]

[ "GO:0140392", "GO:1902494" ]

[]

null

false

true

1