go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0005602
5,602
complement component C1 complex
cellular_component
A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "complement component C1q complex" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0140392" ]
[ "has_part GO:0062167" ]
[ "has_part" ]
[ "GO:0062167" ]
[ "GO:0062167", "GO:0140392" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005603
5,603
obsolete complement component C2 complex
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mah" ]
This term was made obsolete because prior to cleavage, complement component C2 is a single polypeptide rather than a complex, and after cleavage the products do not remain physically associated; there is thus no known biological entity corresponding to "complement C2 complex".
[ "complement component C2 complex" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
8
GO:0005604
5,604
basement membrane
cellular_component
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
[ "PMID:22505934", "PMID:33605520", "PMID:39223427" ]
Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer.
[ "basal lamina", "basement lamina", "lamina densa" ]
[ "RELATED", "RELATED", "RELATED" ]
[ "GO:0005605", "GO:0008003" ]
[]
[ "Wikipedia:Basement_membrane" ]
[ "GO:0031012" ]
[]
[]
[]
[ "GO:0031012" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29267\" xsd:anyURI" ]
null
null
false
true
4
GO:0005606
5,606
laminin-111 trimer
cellular_component
A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]
null
[ "laminin-1 complex", "laminin-111 complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]
null
null
false
true
2
GO:0005607
5,607
laminin-211 trimer
cellular_component
A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.
[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]
null
[ "laminin-2 complex", "laminin-211 complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]
null
null
false
true
6
GO:0005608
5,608
laminin-121 trimer
cellular_component
A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]
null
[ "laminin-121 complex", "laminin-3 complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]
null
null
false
true
4
GO:0005609
5,609
laminin-221 trimer
cellular_component
A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.
[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]
null
[ "laminin-221 complex", "laminin-4 complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]
null
null
false
true
1
GO:0005611
5,611
laminin-311 trimer
cellular_component
A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.
[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]
null
[ "laminin-311 complex", "laminin-6 complex", "laminin-6A complex" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]
null
null
false
true
6
GO:0005612
5,612
laminin-321 trimer
cellular_component
A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.
[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]
null
[ "laminin-321 complex", "laminin-7 complex", "laminin-7A" ]
[ "NARROW", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[ "GO:0043256" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]
null
null
false
true
2
GO:0005613
5,613
obsolete laminin receptor protein
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it is out of date. It seems to be referring to the non-integrin 34/67kDa laminin receptor, which new research has shown to actually be a ribosomal protein of the SP2 family.
[ "laminin receptor protein" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0008305" ]
[]
null
null
true
true
7
GO:0005614
5,614
interstitial matrix
cellular_component
A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
[ "PMID:33605520", "PMID:39223427", "PMID:8450001" ]
null
[]
[]
[]
[]
[]
[ "GO:0031012" ]
[]
[]
[]
[ "GO:0031012" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29267\" xsd:anyURI" ]
null
null
false
true
1
GO:0005615
5,615
obsolete extracellular space
cellular_component
OBSOLETE. That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
[ "ISBN:0198547684" ]
This term was obsoleted because it represents the same concept as extracellular region; GO:0005576.
[ "intercellular space" ]
[ "RELATED" ]
[]
[]
[ "NIF_Subcellular:sao1425028079" ]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005576" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31545\" xsd:anyURI" ]
null
null
true
true
6
GO:0005616
5,616
larval serum protein complex
cellular_component
A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.
[ "GOC:jl", "PMID:6781759" ]
null
[]
[]
[]
[]
[]
[ "GO:0140392" ]
[]
[]
[]
[ "GO:0140392" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005618
5,618
cell wall
cellular_component
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it...
[ "GOC:giardia", "ISBN:0198547684", "PMID:15134259", "Wikipedia:Microbial_cyst" ]
Not to be used for manual annotation. Please choose a more specific term: for bacteria, annotate to GO:0009274; peptidoglycan-based cell wall, for plants: annotate to GO:0009505 ; plant-type cell wall, for fungi: GO:0009277 ; fungal-type cell wall, and for archae, use GO:0030115 S-layer (see PMID:31214995).
[]
[]
[]
[ "gocheck_do_not_annotate", "goslim_candida", "goslim_chembl", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_metagenomics", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_prokaryote", "goslim_prokaryote_ribbon", "goslim_yeast" ]
[ "Wikipedia:Cell_wall" ]
[ "GO:0030312" ]
[]
[]
[]
[ "GO:0030312" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21669\" xsd:anyURI" ]
null
null
false
true
4
GO:0005619
5,619
ascospore wall
cellular_component
The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.
[ "GOC:vw", "PMID:36266346" ]
null
[ "fungal-type spore wall" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0009277", "GO:0031160" ]
[]
[]
[]
[ "GO:0009277", "GO:0031160" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0005621
5,621
cellular bud scar
cellular_component
Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.
[ "GOC:rn", "PMID:14600225", "PMID:2005820" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0009277" ]
[ "part_of" ]
[ "GO:0009277" ]
[ "GO:0009277", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0005622
5,622
intracellular anatomical structure
cellular_component
A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
[ "ISBN:0198506732" ]
null
[ "internal to cell", "intracellular", "nucleocytoplasm", "protoplasm", "protoplast" ]
[ "EXACT", "EXACT", "RELATED", "EXACT", "RELATED" ]
[]
[ "gocheck_do_not_annotate", "goslim_chembl", "goslim_metagenomics", "goslim_plant" ]
[ "Wikipedia:Intracellular" ]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17776\" xsd:anyURI" ]
null
null
false
true
1
GO:0005623
5,623
obsolete cell
cellular_component
OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
[ "GOC:curators" ]
This term was obsoleted because it was redundant with the root class of the cell ontology, CL:0000000.
[]
[]
[]
[]
[ "NIF_Subcellular:sao1813327414", "Wikipedia:Cell_(biology)" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "IAO:0000589 \"cell and encapsulating structures\" xsd:string", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19036\" xsd:anyURI" ]
null
null
true
true
1
GO:0005624
5,624
obsolete membrane fraction
cellular_component
OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.
[ "GOC:ma" ]
This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.
[ "membrane fraction" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0016020" ]
[]
null
null
true
true
7
GO:0005625
5,625
obsolete soluble fraction
cellular_component
OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water.
[ "GOC:ma" ]
This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.
[ "soluble", "soluble fraction" ]
[ "BROAD", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005575" ]
[]
null
null
true
true
9
GO:0005626
5,626
obsolete insoluble fraction
cellular_component
OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water.
[ "GOC:ma" ]
This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.
[ "insoluble fraction", "particle-bound" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005575" ]
[]
null
null
true
true
7
GO:0005627
5,627
obsolete ascus
cellular_component
OBSOLETE. A sac-like fruiting body (ascomycete Fungi); contains ascospores (typically eight in number).
[ "ISBN:0198547684" ]
This term was made obsolete because it is a structure that contains cell (ascospores) rather than a cellular component. To update annotations, consider the external ontology term 'ascus ; FAO:0000014'.
[ "ascus" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
1
GO:0005630
5,630
dityrosine layer of spore wall
cellular_component
The outermost layer of the spore wall, as described in Saccharomyces.
[ "ISBN:0879693568" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005619" ]
[ "part_of" ]
[ "GO:0005619" ]
[ "GO:0005619", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0005631
5,631
chitosan layer of spore wall
cellular_component
The second outermost layer of the spore wall, as described in Saccharomyces.
[ "ISBN:0879693568" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005619" ]
[ "part_of" ]
[ "GO:0005619" ]
[ "GO:0005619", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005632
5,632
inner layer of spore wall
cellular_component
Either of the two innermost layers of the spore wall, as described in Saccharomyces.
[ "ISBN:0879693568" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005619" ]
[ "part_of" ]
[ "GO:0005619" ]
[ "GO:0005619", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0005633
5,633
ascus lipid droplet
cellular_component
Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins.
[ "GOC:mah", "PMID:12702293" ]
null
[ "ascus lipid particle" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0005811" ]
[]
[]
[]
[ "GO:0005811" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0005634
5,634
nucleus
cellular_component
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA repl...
[ "GOC:curators" ]
null
[ "cell nucleus", "horsetail nucleus" ]
[ "EXACT", "NARROW" ]
[]
[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_flybase_ribbon", "goslim_generic", "goslim_metagenomics", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_yeast" ]
[ "NIF_Subcellular:sao1702920020", "Wikipedia:Cell_nucleus" ]
[ "GO:0043231" ]
[]
[]
[]
[ "GO:0043231" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005635
5,635
nuclear envelope
cellular_component
The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore compl...
[ "ISBN:0198547684", "PMID:16164970" ]
null
[]
[]
[ "GO:0005636" ]
[ "goslim_chembl", "goslim_generic", "goslim_plant" ]
[ "Wikipedia:Nuclear_envelope" ]
[ "GO:0031967" ]
[ "part_of GO:0005634", "part_of GO:0012505" ]
[ "part_of", "part_of" ]
[ "GO:0005634", "GO:0012505" ]
[ "GO:0005634", "GO:0012505", "GO:0031967" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29832\" xsd:anyURI" ]
null
null
false
true
5
GO:0005637
5,637
nuclear inner membrane
cellular_component
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
[ "GOC:ma" ]
null
[ "inner envelope", "inner nuclear membrane", "nucleus inner membrane" ]
[ "BROAD", "EXACT", "EXACT" ]
[]
[]
[ "NIF_Subcellular:sao1612527463" ]
[ "GO:0019866", "GO:0031965" ]
[]
[]
[]
[ "GO:0019866", "GO:0031965" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005638
5,638
lamin filament
cellular_component
Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C.
[ "ISBN:0198547684" ]
null
[ "type V intermediate filament" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0005882" ]
[ "part_of GO:0005652" ]
[ "part_of" ]
[ "GO:0005652" ]
[ "GO:0005652", "GO:0005882" ]
[ "GO:0005882", "part_of GO:0005652" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005639
5,639
obsolete integral component of nuclear inner membrane
cellular_component
OBSOLETE. The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
[ "GOC:curators" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "integral to nuclear inner membrane" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005637" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
4
GO:0005640
5,640
nuclear outer membrane
cellular_component
The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.
[ "ISBN:0198547684" ]
null
[ "nucleus outer envelope", "perinuclear membrane" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "NIF_Subcellular:sao1617136075" ]
[ "GO:0031965", "GO:0031968" ]
[ "part_of GO:0042175" ]
[ "part_of" ]
[ "GO:0042175" ]
[ "GO:0031965", "GO:0031968", "GO:0042175" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005641
5,641
nuclear envelope lumen
cellular_component
The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.
[ "GOC:ai" ]
Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'.
[ "nuclear intermembrane space", "nuclear membrane lumen", "perinuclear space" ]
[ "EXACT", "RELATED", "EXACT" ]
[ "GO:0005653" ]
[]
[]
[ "GO:0031970" ]
[ "part_of GO:0005635" ]
[ "part_of" ]
[ "GO:0005635" ]
[ "GO:0005635", "GO:0031970" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0005642
5,642
annulate lamellae
cellular_component
Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER.
[ "PMID:12631728" ]
null
[]
[]
[]
[]
[]
[ "GO:0016020" ]
[ "part_of GO:0042175" ]
[ "part_of" ]
[ "GO:0042175" ]
[ "GO:0016020", "GO:0042175" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005643
5,643
nuclear pore
cellular_component
A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
[ "ISBN:0198547684" ]
null
[ "NPC", "nuclear pore complex", "nuclear pore membrane protein", "nucleopore" ]
[ "EXACT", "EXACT", "NARROW", "EXACT" ]
[ "GO:0005644" ]
[ "goslim_pir" ]
[ "NIF_Subcellular:sao220861693", "Wikipedia:Nuclear_pore" ]
[ "GO:0140513" ]
[ "part_of GO:0005635" ]
[ "part_of" ]
[ "GO:0005635" ]
[ "GO:0005635", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005646
5,646
obsolete importin
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "importin", "karyopherin" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005634", "GO:0005643", "GO:0005737", "GO:0017056" ]
[]
null
null
true
true
7
GO:0005647
5,647
obsolete importin, alpha-subunit
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "importin, alpha-subunit", "karyopherin-alpha" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005634", "GO:0005643", "GO:0005737", "GO:0017056" ]
[]
null
null
true
true
2
GO:0005648
5,648
obsolete importin, beta-subunit
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "importin, beta-subunit", "karyopherin-beta1" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005634", "GO:0005643", "GO:0005737", "GO:0017056" ]
[]
null
null
true
true
5
GO:0005649
5,649
obsolete transportin
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "karyopherin-beta2", "transportin" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005634", "GO:0005643", "GO:0005737" ]
[]
null
null
true
true
3
GO:0005650
5,650
obsolete importin, alpha-subunit transport factor
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "CAS", "importin, alpha-subunit transport factor" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005634", "GO:0005643", "GO:0005737" ]
[]
null
null
true
true
5
GO:0005651
5,651
obsolete exportin
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "exportin" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005634", "GO:0005643", "GO:0005737", "GO:0017056" ]
[]
null
null
true
true
7
GO:0005652
5,652
nuclear lamina
cellular_component
The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C...
[ "ISBN:0198506732", "ISBN:0716731363" ]
null
[]
[]
[]
[]
[ "NIF_Subcellular:sao1455996588", "Wikipedia:Nuclear_lamina" ]
[ "GO:0110165" ]
[ "part_of GO:0005635", "part_of GO:0034399" ]
[ "part_of", "part_of" ]
[ "GO:0005635", "GO:0034399" ]
[ "GO:0005635", "GO:0034399", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005654
5,654
nucleoplasm
cellular_component
That part of the nuclear content other than the chromosomes or the nucleolus.
[ "GOC:ma", "ISBN:0124325653" ]
null
[]
[]
[]
[ "goslim_chembl", "goslim_generic", "goslim_plant" ]
[ "NIF_Subcellular:sao661522542", "Wikipedia:Nucleoplasm" ]
[ "GO:0110165" ]
[ "part_of GO:0031981" ]
[ "part_of" ]
[ "GO:0031981" ]
[ "GO:0031981", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005655
5,655
nucleolar ribonuclease P complex
cellular_component
A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several prote...
[ "GOC:mah", "PMID:12045094" ]
null
[ "nucleolar RNase P complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030681", "GO:0140513" ]
[ "part_of GO:0005730" ]
[ "part_of" ]
[ "GO:0005730" ]
[ "GO:0005730", "GO:0030681", "GO:0140513" ]
[ "GO:0030677", "part_of GO:0005730" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0005656
5,656
nuclear pre-replicative complex
cellular_component
A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
[ "PMID:15222894" ]
null
[ "eukaryotic pre-replicative complex", "pre-RC", "pre-replicative complex" ]
[ "EXACT", "RELATED", "BROAD" ]
[]
[]
[]
[ "GO:0036387", "GO:0140513" ]
[ "has_part GO:0000808", "has_part GO:0042555", "part_of GO:0005654" ]
[ "has_part", "has_part", "part_of" ]
[ "GO:0000808", "GO:0042555", "GO:0005654" ]
[ "GO:0000808", "GO:0005654", "GO:0036387", "GO:0042555", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0005657
5,657
replication fork
cellular_component
The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
[ "GOC:mah", "ISBN:0198547684" ]
null
[ "replication focus" ]
[ "RELATED" ]
[]
[]
[ "Wikipedia:Replication_fork" ]
[ "GO:0110165" ]
[ "part_of GO:0005694" ]
[ "part_of" ]
[ "GO:0005694" ]
[ "GO:0005694", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005658
5,658
alpha DNA polymerase:primase complex
cellular_component
A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a small stretch of DNA. The smaller of the two primase subunits alone...
[ "GOC:mah", "PMID:11395402", "PMID:26975377" ]
null
[ "DNA polymerase alpha:primase complex", "heterotetrameric polymerase alpha holoenzyme", "pol-prim", "primosome" ]
[ "EXACT", "EXACT", "RELATED", "BROAD" ]
[]
[]
[]
[ "GO:0042575", "GO:0055029" ]
[ "part_of GO:0043601" ]
[ "part_of" ]
[ "GO:0043601" ]
[ "GO:0042575", "GO:0043601", "GO:0055029" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005660
5,660
obsolete delta-DNA polymerase cofactor complex
cellular_component
OBSOLETE. A complex of proteins that interacts with delta-DNA polymerase, promoting elongation. In humans it is a heteropentamer of subunits of 140/145, 40, 38, 37 and 36.5 kDa, which form a complex with the proliferating cell nuclear antigen (PCNA) in the presence of ATP.
[ "GOC:jl" ]
This term was made obsolete because it refers to two distinct complexes, PCNA and Replication factor C (RFC), the latter of which is already represented as a separate, unrelated GO term (DNA replication factor C complex ; GO:0005663). In addition, the phrase 'delta-DNA polymerase cofactor' to represent both PCNA and RF...
[ "delta DNA polymerase cofactor complex", "delta-DNA polymerase cofactor complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005663", "GO:0043626" ]
[]
null
null
true
true
6
GO:0005662
5,662
DNA replication factor A complex
cellular_component
A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa...
[ "PMID:9242902" ]
null
[ "replication protein A", "RPA" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "Wikipedia:Replication_protein_A" ]
[ "GO:0140513" ]
[ "part_of GO:0043601" ]
[ "part_of" ]
[ "GO:0043601" ]
[ "GO:0043601", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0005663
5,663
DNA replication factor C complex
cellular_component
A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.
[ "PMID:14614842", "PMID:14646196", "PMID:16172520" ]
null
[ "activator 1 complex", "RFC complex" ]
[ "EXACT", "EXACT" ]
[]
[ "goslim_pir" ]
[]
[ "GO:0032991" ]
[ "part_of GO:0005657" ]
[ "part_of" ]
[ "GO:0005657" ]
[ "GO:0005657", "GO:0032991" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0005664
5,664
nuclear origin of replication recognition complex
cellular_component
A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.
[ "GOC:elh" ]
null
[ "eukaryotic ORC", "nuclear ORC" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0000808", "GO:0140513" ]
[ "part_of GO:0000228" ]
[ "part_of" ]
[ "GO:0000228" ]
[ "GO:0000228", "GO:0000808", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005665
5,665
RNA polymerase II, core complex
cellular_component
RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacter...
[ "GOC:krc", "GOC:mtg_sensu" ]
null
[ "DNA-directed RNA polymerase II, core complex", "RNA polymerase II complex", "RNAP II complex" ]
[ "EXACT", "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0055029" ]
[ "part_of GO:0016591" ]
[ "part_of" ]
[ "GO:0016591" ]
[ "GO:0016591", "GO:0055029" ]
[ "GO:0000428", "part_of GO:0016591" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0005666
5,666
RNA polymerase III complex
cellular_component
RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryoti...
[ "GOC:krc", "GOC:mtg_sensu" ]
null
[ "DNA-directed RNA polymerase III activity", "DNA-directed RNA polymerase III complex" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0000428", "GO:0140513" ]
[]
[]
[]
[ "GO:0000428", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005667
5,667
transcription regulator complex
cellular_component
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
[ "GOC:jl" ]
null
[ "cytoplasmic transcription factor complex", "nuclear transcription factor complex", "transcription factor complex" ]
[ "RELATED", "RELATED", "RELATED" ]
[ "GO:0044797", "GO:0044798" ]
[ "goslim_pir" ]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
jl
2013-08-28T12:11:37Z
false
true
2
GO:0005670
5,670
obsolete transcription-activating factor, 30kD
cellular_component
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it represents a single gene product and not a complex.
[ "transcription-activating factor, 30kD" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005669" ]
[]
[]
null
null
true
true
7
GO:0005671
5,671
obsolete Ada2/Gcn5/Ada3 transcription activator complex
cellular_component
OBSOLETE. A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in o...
[ "PMID:10637607" ]
This term was obsoleted because it was incorrectly annotated. Consider ADA complex ; GO:0140671 or ATAC complex; GO:0140672.
[ "ATAC complex" ]
[ "RELATED" ]
[ "GO:0002928" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0140671", "GO:0140672" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21335\" xsd:anyURI" ]
null
null
true
true
1
GO:0005672
5,672
transcription factor TFIIA complex
cellular_component
A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).
[ "GOC:jl", "PMID:17560669" ]
null
[]
[]
[]
[]
[]
[ "GO:0090575" ]
[ "part_of GO:0016591" ]
[ "part_of" ]
[ "GO:0016591" ]
[ "GO:0016591", "GO:0090575" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29934\" xsd:anyURI" ]
null
null
false
true
7
GO:0005673
5,673
transcription factor TFIIE complex
cellular_component
A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH.
[ "GOC:jl", "PMID:16547462" ]
null
[]
[]
[]
[]
[]
[ "GO:0090575" ]
[ "part_of GO:0016591" ]
[ "part_of" ]
[ "GO:0016591" ]
[ "GO:0016591", "GO:0090575" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29934\" xsd:anyURI" ]
null
null
false
true
2
GO:0005674
5,674
transcription factor TFIIF complex
cellular_component
A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.
[ "GOC:jl", "PMID:7597077" ]
null
[]
[]
[]
[]
[]
[ "GO:0090575" ]
[ "part_of GO:0016591" ]
[ "part_of" ]
[ "GO:0016591" ]
[ "GO:0016591", "GO:0090575" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005675
5,675
transcription factor TFIIH holo complex
cellular_component
A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.
[ "GOC:ew", "GOC:krc", "PMID:14500720", "PMID:22308316", "PMID:22572993", "PMID:7813015" ]
null
[ "CAK complex", "CDK-activating kinase", "cyclin-dependent protein kinase activating kinase holoenzyme complex", "holo TFIIH complex" ]
[ "RELATED", "BROAD", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0019908", "GO:0032806", "GO:0090575" ]
[ "has_part GO:0000439", "part_of GO:0016591" ]
[ "has_part", "part_of" ]
[ "GO:0000439", "GO:0016591" ]
[ "GO:0000439", "GO:0016591", "GO:0019908", "GO:0032806", "GO:0090575" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0005677
5,677
chromatin silencing complex
cellular_component
Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0140513" ]
[]
[]
[]
[ "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005678
5,678
obsolete chromatin assembly complex
cellular_component
OBSOLETE. Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure.
[ "GOC:mah" ]
This term was made obsolete because its definition no longer reflects and cannot be modified to be consistent with the current state of knowledge.
[ "chromatin assembly complex", "nucleosome assembly complex" ]
[ "EXACT", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
4
GO:0005680
5,680
anaphase-promoting complex
cellular_component
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin ...
[ "GOC:jh", "GOC:vw", "PMID:10465783", "PMID:10611969" ]
Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein.
[ "anaphase promoting complex", "APC", "cyclosome" ]
[ "EXACT", "BROAD", "EXACT" ]
[]
[]
[ "Wikipedia:Anaphase-promoting_complex" ]
[ "GO:0000152", "GO:0031461" ]
[]
[]
[]
[ "GO:0000152", "GO:0031461" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0005681
5,681
spliceosomal complex
cellular_component
Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate ...
[ "GOC:editors", "GOC:mah", "ISBN:0198547684", "PMID:19239890" ]
null
[ "spliceosome", "spliceosome complex" ]
[ "BROAD", "EXACT" ]
[]
[ "goslim_pir" ]
[ "Wikipedia:Spliceosome" ]
[ "GO:0140513", "GO:1990904" ]
[]
[]
[]
[ "GO:0140513", "GO:1990904" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0005682
5,682
U5 snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "snRNP U5" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005683
5,683
U7 snRNP
cellular_component
A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs.
[ "PMID:12872004" ]
null
[ "snRNP U7" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030532" ]
[]
[]
[]
[ "GO:0030532" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0005684
5,684
U2-type spliceosomal complex
cellular_component
Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
[ "GOC:krc", "GOC:mah", "PMID:11343900" ]
A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.
[ "GT-AG spliceosome", "major (U2-type) spliceosomal complex", "major spliceosomal complex" ]
[ "NARROW", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0005681" ]
[]
[]
[]
[ "GO:0005681" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005685
5,685
U1 snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "snRNP U1" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0005686
5,686
U2 snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
U2 snRNP refers to the U2 small nuclear RNA and the proteins that associate with it. U2 snRNP is not considered to be a type of spliceosomal complex by itself.
[ "17S U2 snRNP", "snRNP U2" ]
[ "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0005687
5,687
U4 snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U4, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4 snRNP, most of which remain associated with the U4 snRNA both while the U4 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "snRNP U4" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005688
5,688
U6 snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U6, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6 snRNP, most of which remain associated with the U6 snRNA both while the U6 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "snRNP U6" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[ "has_part GO:0120115" ]
[ "has_part" ]
[ "GO:0120115" ]
[ "GO:0097525", "GO:0120115" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005689
5,689
U12-type spliceosomal complex
cellular_component
Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire s...
[ "GOC:krc", "GOC:mah", "PMID:11574683", "PMID:11971955" ]
null
[ "AT-AC spliceosomal complex", "minor (U12-type) spliceosomal complex", "minor spliceosomal complex" ]
[ "NARROW", "EXACT", "EXACT" ]
[]
[]
[ "Wikipedia:Minor_spliceosome" ]
[ "GO:0005681" ]
[]
[]
[]
[ "GO:0005681" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0005690
5,690
U4atac snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of...
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "snRNP U4atac" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005691
5,691
U6atac snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U6atac, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6atac snRNP, most of which remain associated with the U6atac snRNA both while the U6atac snRNP is free or assembled into the U4atac/U6atac snRNP or into a series of...
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "snRNP U6atac" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005692
5,692
U11 snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "12S U11 snRNP", "snRNP U11" ]
[ "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0005693
5,693
U12 snRNP
cellular_component
A ribonucleoprotein complex that contains small nuclear RNA U12, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U12 snRNP, most of which remain associated with the U12 snRNA both while the U12 snRNP is free or assembled into a series of spliceosomal complexes.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "snRNP U12" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[ "GO:0097525" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0005694
5,694
chromosome
cellular_component
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
[ "ISBN:0198547684" ]
Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.
[ "chromatid", "interphase chromosome", "prophase chromosome" ]
[ "RELATED", "NARROW", "NARROW" ]
[]
[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_flybase_ribbon", "goslim_generic", "goslim_metagenomics", "goslim_pir", "goslim_prokaryote", "goslim_prokaryote_ribbon", "goslim_yeast" ]
[ "Wikipedia:Chromosome" ]
[ "GO:0043232" ]
[]
[]
[]
[ "GO:0043232" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0005695
5,695
obsolete chromatid
cellular_component
OBSOLETE. One of the two daughter strands of a duplicated chromosome that become apparent between early prophase and metaphase in mitosis and between diplotene and second metaphase in meiosis.
[ "ISBN:0198506732" ]
This term was made obsolete because it is not a unique subcellular component, i.e. the difference between this term and 'chromosome' is based on temporal and process distinctions.
[ "chromatid" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000793", "GO:0000794", "GO:0005694" ]
[]
null
null
true
true
5
GO:0005697
5,697
telomerase holoenzyme complex
cellular_component
Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.
[ "PMID:11884619" ]
null
[]
[]
[]
[ "goslim_pir" ]
[]
[ "GO:0140513", "GO:1902494", "GO:1990904" ]
[]
[]
[]
[ "GO:0140513", "GO:1902494", "GO:1990904" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0005698
5,698
obsolete centromere
cellular_component
OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromos...
[ "ISBN:0198506732" ]
This term was made obsolete because it is a genetically defined region and not a specific subcellular localization.
[ "centromere" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000775" ]
[]
null
null
true
true
5
GO:0005700
5,700
polytene chromosome
cellular_component
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
[ "ISBN:0198506732" ]
null
[]
[]
[]
[]
[ "Wikipedia:Polytene_chromosome" ]
[ "GO:0005694" ]
[]
[]
[]
[ "GO:0005694" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0005701
5,701
polytene chromosome chromocenter
cellular_component
A region at which the centric regions of polytene chromosomes are joined together.
[ "GOC:bf", "ISBN:0120649012" ]
null
[ "polytene chromosome chromocentre" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0010369" ]
[ "part_of GO:0005700" ]
[ "part_of" ]
[ "GO:0005700" ]
[ "GO:0005700", "GO:0010369" ]
[ "GO:0010369", "part_of GO:0005700" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0005702
5,702
polytene chromosome weak point
cellular_component
A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization.
[ "GOC:bf", "ISBN:0120649012" ]
null
[ "constriction" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005700" ]
[ "part_of" ]
[ "GO:0005700" ]
[ "GO:0005700", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0005703
5,703
polytene chromosome puff
cellular_component
A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
[ "GOC:bf", "ISBN:0120649012" ]
null
[]
[]
[]
[]
[]
[ "GO:0098687" ]
[ "part_of GO:0005700" ]
[ "part_of" ]
[ "GO:0005700" ]
[ "GO:0005700", "GO:0098687" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0005705
5,705
polytene chromosome interband
cellular_component
A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.
[ "GOC:bf", "PMID:11361342" ]
null
[]
[]
[]
[]
[]
[ "GO:0098687" ]
[ "part_of GO:0005700" ]
[ "part_of" ]
[ "GO:0005700" ]
[ "GO:0005700", "GO:0098687" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005707
5,707
obsolete interphase chromosome
cellular_component
OBSOLETE. A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently.
[ "GOC:ai", "ISBN:0815316194" ]
This term was made obsolete because it is based on a temporal division of the cell cycle.
[ "interphase chromosome" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005694" ]
[]
null
null
true
true
3
GO:0005708
5,708
obsolete mitotic chromosome
cellular_component
OBSOLETE. A chromosome involved in the process of mitosis.
[ "GOC:ai" ]
This term was made obsolete because it is based on a process.
[ "mitotic chromosome" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000793", "GO:0000794" ]
[]
null
null
true
true
4
GO:0005709
5,709
obsolete prophase chromosome
cellular_component
OBSOLETE. A chromosome found in the cell during prophase.
[ "GOC:ai" ]
This term was made obsolete because it is based on a temporal division of the cell cycle.
[ "prophase chromosome" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005694" ]
[]
null
null
true
true
1
GO:0005710
5,710
obsolete metaphase chromosome
cellular_component
OBSOLETE. A chromosome found in the cell during metaphase. Typically, sister chromatids are held together at their centromeres and chromosomes are covered with a large number of molecules, including ribonucleoproteins.
[ "GOC:ai" ]
This term was made obsolete because it is based on a temporal division of the cell cycle.
[ "metaphase chromosome" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000793", "GO:0000794" ]
[]
null
null
true
true
2
GO:0005711
5,711
obsolete meiotic chromosome
cellular_component
OBSOLETE. A chromosome involved in the process of meiosis.
[ "GOC:ai" ]
This term was made obsolete because it is based on a process.
[ "meiotic chromosome" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000794" ]
[]
null
null
true
true
7
GO:0005712
5,712
chiasma
cellular_component
A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over.
[ "ISBN:0198506732" ]
null
[]
[]
[]
[]
[ "Wikipedia:Chiasma_(genetics)" ]
[ "GO:0110165" ]
[ "part_of GO:0000794" ]
[ "part_of" ]
[ "GO:0000794" ]
[ "GO:0000794", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0005713
5,713
recombination nodule
cellular_component
An electron dense structure that is associated with meiotic chromosomes.
[ "GOC:elh" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0000794" ]
[ "part_of" ]
[ "GO:0000794" ]
[ "GO:0000794", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005714
5,714
early recombination nodule
cellular_component
An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I.
[ "GOC:elh" ]
null
[]
[]
[]
[]
[]
[ "GO:0005713" ]
[]
[]
[]
[ "GO:0005713" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0005715
5,715
late recombination nodule
cellular_component
An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I.
[ "GOC:elh" ]
null
[]
[]
[]
[]
[]
[ "GO:0005713" ]
[]
[]
[]
[ "GO:0005713" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0005722
5,722
beta-heterochromatin
cellular_component
A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization.
[ "PMID:11404334", "PMID:8878678" ]
null
[]
[]
[]
[]
[]
[ "GO:0005721" ]
[ "part_of GO:0005701" ]
[ "part_of" ]
[ "GO:0005701" ]
[ "GO:0005701", "GO:0005721" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0005723
5,723
alpha-heterochromatin
cellular_component
A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization.
[ "PMID:8878678" ]
null
[]
[]
[]
[]
[]
[ "GO:0005721" ]
[ "part_of GO:0005701" ]
[ "part_of" ]
[ "GO:0005701" ]
[ "GO:0005701", "GO:0005721" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0005724
5,724
obsolete nuclear telomeric heterochromatin
cellular_component
OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus.
[ "GOC:ai" ]
This term was obsoleted because there is no heterochromatin at the telomere and the term had been used inconsistently.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19086\" xsd:anyURI" ]
null
null
true
true
2
GO:0005725
5,725
intercalary heterochromatin
cellular_component
Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes.
[ "PMID:14579245" ]
null
[]
[]
[]
[]
[]
[ "GO:0000792" ]
[]
[]
[]
[ "GO:0000792" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0005726
5,726
perichromatin fibrils
cellular_component
Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts.
[ "PMID:14731598" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0000228", "part_of GO:0000785" ]
[ "part_of", "part_of" ]
[ "GO:0000228", "GO:0000785" ]
[ "GO:0000228", "GO:0000785", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0005727
5,727
extrachromosomal circular DNA
cellular_component
Circular DNA structures that are not part of a chromosome.
[ "GOC:ai" ]
null
[]
[]
[]
[ "goslim_metagenomics" ]
[]
[ "GO:0005622" ]
[ "part_of GO:0046821" ]
[ "part_of" ]
[ "GO:0046821" ]
[ "GO:0005622", "GO:0046821" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7