LiteFold/GO · Datasets at Hugging Face

GO:0005728

5,728

extrachromosomal rDNA circle

cellular_component

Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats.

[ "GOC:mah", "PMID:12044934" ]

null

[ "extrachromosomal ribosomal DNA circle" ]

[ "EXACT" ]

[]

[ "GO:0005727" ]

[]

[ "GO:0005727" ]

[]

null

false

true

4

GO:0005730

5,730

nucleolus

cellular_component

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5....

[ "ISBN:0198506732" ]

null

[]

[ "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_generic", "goslim_pir", "goslim_plant", "goslim_yeast" ]

[ "NIF_Subcellular:sao1820400233", "Wikipedia:Nucleolus" ]

[ "GO:0043232" ]

[ "part_of GO:0031981" ]

[ "part_of" ]

[ "GO:0031981" ]

[ "GO:0031981", "GO:0043232" ]

[]

null

false

true

6

GO:0005731

5,731

nucleolus organizer region

cellular_component

A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed.

[ "PMID:14504406" ]

null

[ "NOR", "nucleolus organiser region", "nucleolus organizer complex" ]

[ "EXACT", "EXACT", "RELATED" ]

[]

[ "Wikipedia:Nucleolus_organizer_region" ]

[ "GO:0030874" ]

[]

[ "GO:0030874" ]

[]

null

false

true

9

GO:0005732

5,732

sno(s)RNA-containing ribonucleoprotein complex

cellular_component

A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or bo...

[ "GOC:krc", "GOC:mah", "ISBN:0879695897", "PMID:17284456" ]

Note that 'nucleolar' in the name acronym 'snoRNA' is part of the RNA family designation 'small nucleolar', and does not reflect the location of the complex. Both box C/D type and box H/ACA RNAs are found in Archaea (where they are referred to as sRNAs) as well as in Eukaryota. In eukaryotes, box H/ACA RNAs are found i...

[ "small nucleolar ribonucleoprotein", "small nucleolar ribonucleoprotein complex", "small ribonucleoprotein", "small ribonucleoprotein protein complex", "snoRNP", "sRNP" ]

[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "goslim_pir" ]

[]

[ "GO:1990904" ]

[]

[ "GO:1990904" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20416\" xsd:anyURI" ]

null

false

true

2

GO:0005733

5,733

obsolete small nucleolar RNA

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a gene product.

[ "small nucleolar RNA", "snoRNA" ]

[ "EXACT", "EXACT" ]

[]

null

true

9

GO:0005735

5,735

obsolete box H + ACA snoRNP protein

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a gene product.

[ "box H + ACA snoRNP protein" ]

[ "EXACT" ]

[]

null

true

4

GO:0005736

5,736

RNA polymerase I complex

cellular_component

RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. ...

[ "GOC:krc", "GOC:mtg_sensu" ]

null

[ "DNA-directed RNA polymerase I activity", "DNA-directed RNA polymerase I complex" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0000428", "GO:0140513" ]

[ "part_of GO:0005730" ]

[ "part_of" ]

[ "GO:0005730" ]

[ "GO:0000428", "GO:0005730", "GO:0140513" ]

[]

null

false

true

2

GO:0005739

5,739

mitochondrion

cellular_component

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

[ "GOC:giardia", "ISBN:0198506732" ]

Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products loc...

[ "mitochondria" ]

[ "EXACT" ]

[]

[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_flybase_ribbon", "goslim_generic", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_yeast" ]

[ "NIF_Subcellular:sao1860313010", "Wikipedia:Mitochondrion" ]

[ "GO:0043231" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0043231" ]

[]

null

false

true

6

GO:0005740

5,740

mitochondrial envelope

cellular_component

The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.

[ "GOC:ai", "GOC:pz" ]

null

[]

[ "goslim_candida", "goslim_yeast" ]

[]

[ "GO:0031967" ]

[ "part_of GO:0005739" ]

[ "part_of" ]

[ "GO:0005739" ]

[ "GO:0005739", "GO:0031967" ]

[]

null

false

true

5

GO:0005741

5,741

mitochondrial outer membrane

cellular_component

The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.

[ "GOC:ai" ]

null

[ "mitochondrion outer membrane", "outer mitochondrial membrane", "outer mitochondrion membrane" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "NIF_Subcellular:sao1289741256", "Wikipedia:Outer_mitochondrial_membrane" ]

[ "GO:0031966", "GO:0031968" ]

[]

[ "GO:0031966", "GO:0031968" ]

[]

null

false

true

3

GO:0005742

5,742

mitochondrial outer membrane translocase complex

cellular_component

A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.

[ "PMID:12581629" ]

null

[ "GIP complex", "mitochondrion outer membrane translocase complex" ]

[ "NARROW", "EXACT" ]

[]

[ "GO:0098799" ]

[]

[ "GO:0098799" ]

[]

null

false

true

1

GO:0005743

5,743

mitochondrial inner membrane

cellular_component

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

[ "GOC:ai" ]

null

[ "inner mitochondrial membrane", "inner mitochondrion membrane", "mitochondrion inner membrane" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "NIF_Subcellular:sao1371347282", "Wikipedia:Inner_mitochondrial_membrane" ]

[ "GO:0019866", "GO:0031966" ]

[]

[ "GO:0019866", "GO:0031966" ]

[]

null

false

true

9

GO:0005744

5,744

TIM23 mitochondrial import inner membrane translocase complex

cellular_component

The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transientl...

[ "PMID:27554484", "PMID:8851659" ]

See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.

[ "mitochondrial inner membrane pre-sequence translocase complex", "mitochondrial inner membrane presequence translocase complex", "mitochondrial inner membrane translocase complex", "Tim23 complex" ]

[ "EXACT", "EXACT", "BROAD", "EXACT" ]

[]

[ "goslim_pir" ]

[]

[ "GO:0098800" ]

[]

[ "GO:0098800" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21246\" xsd:anyURI" ]

null

false

true

5

GO:0005746

5,746

obsolete mitochondrial respirasome

cellular_component

OBSOLETE. The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembra...

[ "GOC:curators", "GOC:ecd", "ISBN:0198547684" ]

The reason for obsoletion is that this term unnecssarily specified a cellular compartment.

[ "mitochondrial electron transport chain", "mitochondrial respiratory chain", "mitochondrial respiratory chain supercomplex", "mitochondrial respiratory supercomplex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[ "GO:0097249" ]

[]

[ "GO:0098803" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12846\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27253\" xsd:anyURI" ]

pr

2012-02-23T05:13:54Z

true

4

GO:0005747

5,747

obsolete mitochondrial respiratory chain complex I

cellular_component

OBSOLETE. A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The i...

[ "GOC:mtg_sensu", "ISBN:0198547684" ]

The reason for obsoletion is that this term unnecssarily specified a cellular compartment.

[]

[ "GO:0005748" ]

[]

[ "GO:0045271" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27253\" xsd:anyURI" ]

null

true

2

GO:0005749

5,749

obsolete mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)

cellular_component

OBSOLETE. A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with ...

[ "GOC:mtg_sensu", "GOC:vw", "ISBN:0198547684" ]

The reason for obsoletion is that this term unnecssarily specified a cellular compartment.

[ "mitochondrial fumarate reductase complex" ]

[ "EXACT" ]

[ "GO:0008136", "GO:0009362", "GO:0019738", "GO:0030390" ]

[]

[ "GO:0045273" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27253\" xsd:anyURI" ]

null

true

4

GO:0005750

5,750

obsolete mitochondrial respiratory chain complex III

cellular_component

OBSOLETE. A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.

[ "GOC:mtg_sensu", "ISBN:0198547684" ]

The reason for obsoletion is that this term unnecssarily specified a cellular compartment.

[ "mitochondrial coenzyme Q-cytochrome c oxidoreductase complex", "mitochondrial coenzyme Q-cytochrome c reductase complex", "mitochondrial complex III", "mitochondrial cytochrome bc(1) complex", "mitochondrial cytochrome bc1 complex", "mitochondrial electron transport complex III", "mitochondrial ubiquin...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "EXACT" ]

[ "GO:0015008" ]

[]

[ "GO:0045275" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27253\" xsd:anyURI" ]

null

true

2

GO:0005753

5,753

obsolete mitochondrial proton-transporting ATP synthase complex

cellular_component

OBSOLETE. A proton-transporting ATP synthase complex found in the mitochondrial membrane.

[ "GOC:mah", "GOC:mtg_sensu" ]

The reason for obsoletion is that this term unnecssarily specified a cellular compartment.

[ "mitochondrial respiratory chain complex V" ]

[ "EXACT" ]

[ "GO:0016470" ]

[]

[ "GO:0045259" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27253\" xsd:anyURI" ]

null

true

9

GO:0005754

5,754

obsolete mitochondrial proton-transporting ATP synthase, catalytic core

cellular_component

OBSOLETE. The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.

[ "GOC:mtg_sensu", "PMID:10838056" ]

The reason for obsoletion is that this term unnecssarily specified a cellular compartment.

[]

[ "GO:0045259" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27253\" xsd:anyURI" ]

null

true

7

GO:0005755

5,755

obsolete hydrogen-transporting ATP synthase, coupling factor CF(0)

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because more specific terms were created.

[ "hydrogen-transporting ATP synthase, coupling factor CF(0)" ]

[ "EXACT" ]

[]

[ "GO:0045259" ]

[]

null

true

9

GO:0005756

5,756

obsolete mitochondrial proton-transporting ATP synthase, central stalk

cellular_component

OBSOLETE. One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.

[ "GOC:mtg_sensu", "PMID:10838056" ]

The reason for obsoletion is that this term unnecssarily specified a cellular compartment.

[]

[ "GO:0045259" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27253\" xsd:anyURI" ]

null

true

6

GO:0005757

5,757

mitochondrial permeability transition pore complex

cellular_component

A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide transloc...

[ "PMID:10393078" ]

null

[ "mitochondrial PT pore complex", "MPTP complex", "PTPC" ]

[ "EXACT", "EXACT", "BROAD" ]

[]

[ "GO:0046930", "GO:0098798" ]

[ "part_of GO:0005740" ]

[ "part_of" ]

[ "GO:0005740" ]

[ "GO:0005740", "GO:0046930", "GO:0098798" ]

[]

null

false

true

9

GO:0005758

5,758

mitochondrial intermembrane space

cellular_component

The region between the inner and outer lipid bilayers of the mitochondrial envelope.

[ "GOC:mah" ]

null

[ "mitochondrial envelope lumen", "mitochondrial membrane lumen" ]

[ "EXACT", "RELATED" ]

[ "GO:0031971" ]

[]

[ "NIF_Subcellular:sao118944228" ]

[ "GO:0031970" ]

[ "part_of GO:0005740" ]

[ "part_of" ]

[ "GO:0005740" ]

[ "GO:0005740", "GO:0031970" ]

[]

null

false

true

8

GO:0005759

5,759

mitochondrial matrix

cellular_component

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

[ "GOC:as", "ISBN:0198506732" ]

null

[ "mitochondrial lumen", "mitochondrial stroma" ]

[ "EXACT", "NARROW" ]

[ "GO:0031980" ]

[]

[ "NIF_Subcellular:sao1804523077", "Wikipedia:Mitochondrial_matrix" ]

[ "GO:0070013" ]

[ "part_of GO:0005739" ]

[ "part_of" ]

[ "GO:0005739" ]

[ "GO:0005739", "GO:0070013" ]

[]

null

false

true

2

GO:0005761

5,761

mitochondrial ribosome

cellular_component

A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.

[ "GOC:mah", "ISBN:0198506732" ]

null

[ "55S ribosome, mitochondrial" ]

[ "NARROW" ]

[]

[ "GO:0000313" ]

[ "part_of GO:0005759" ]

[ "part_of" ]

[ "GO:0005759" ]

[ "GO:0000313", "GO:0005759" ]

[ "GO:0005840", "part_of GO:0005759" ]

[]

null

false

true

7

GO:0005762

5,762

mitochondrial large ribosomal subunit

cellular_component

The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).

[ "GOC:mcc" ]

null

[ "39S ribosomal subunit, mitochondrial" ]

[ "NARROW" ]

[]

[ "GO:0000315", "GO:0098798" ]

[ "part_of GO:0005761" ]

[ "part_of" ]

[ "GO:0005761" ]

[ "GO:0000315", "GO:0005761", "GO:0098798" ]

[ "GO:0015934", "part_of GO:0005761" ]

[]

null

false

true

8

GO:0005763

5,763

mitochondrial small ribosomal subunit

cellular_component

The smaller of the two subunits of a mitochondrial ribosome.

[ "GOC:mcc" ]

null

[ "28S ribosomal subunit, mitochondrial", "mitochondrial ribosomal small subunit complex", "mitochondrial ribosomal SSU complex" ]

[ "NARROW", "EXACT", "EXACT" ]

[]

[ "GO:0000314", "GO:0098798" ]

[ "part_of GO:0005761" ]

[ "part_of" ]

[ "GO:0005761" ]

[ "GO:0000314", "GO:0005761", "GO:0098798" ]

[ "GO:0015935", "part_of GO:0005761" ]

[]

null

false

true

1

GO:0005764

5,764

lysosome

cellular_component

A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysoso...

[ "GOC:mah", "ISBN:0198506732" ]

null

[]

[ "goslim_chembl", "goslim_generic", "goslim_plant" ]

[ "NIF_Subcellular:sao585356902", "Wikipedia:Lysosome" ]

[ "GO:0000323" ]

[]

[ "GO:0000323" ]

[]

null

false

true

6

GO:0005765

5,765

lysosomal membrane

cellular_component

The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.

[ "GOC:ai" ]

null

[ "lysosome membrane" ]

[ "EXACT" ]

[]

[ "GO:0098852" ]

[ "part_of GO:0005764" ]

[ "part_of" ]

[ "GO:0005764" ]

[ "GO:0005764", "GO:0098852" ]

[]

null

false

true

3

GO:0005766

5,766

primary lysosome

cellular_component

A lysosome before it has fused with a vesicle or vacuole.

[ "GOC:jl", "ISBN:0815316194" ]

null

[]

[ "NIF_Subcellular:sao1140587416" ]

[ "GO:0005764" ]

[]

[ "GO:0005764" ]

[]

null

false

true

9

GO:0005767

5,767

secondary lysosome

cellular_component

Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome.

[ "GOC:jl", "ISBN:0815316194" ]

null

[]

[ "NIF_Subcellular:sao1549842807" ]

[ "GO:0005764" ]

[]

[ "GO:0005764" ]

[]

null

false

true

4

GO:0005768

5,768

endosome

cellular_component

A vacuole to which materials ingested by endocytosis are delivered.

[ "ISBN:0198506732", "PMID:19696797" ]

null

[]

[ "goslim_agr", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon" ]

[ "NIF_Subcellular:sao1720343330", "Wikipedia:Endosome" ]

[ "GO:0031410" ]

[ "part_of GO:0012505" ]

[ "part_of" ]

[ "GO:0012505" ]

[ "GO:0012505", "GO:0031410" ]

[]

null

false

true

5

GO:0005769

5,769

early endosome

cellular_component

A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.

[ "GOC:mah", "NIF_Subcellular:nlx_subcell_20090701", "PMID:19696797" ]

null

[]

[ "NIF_Subcellular:nlx_subcell_20090701" ]

[ "GO:0005768" ]

[]

[ "GO:0005768" ]

[]

null

false

true

8

GO:0005770

5,770

late endosome

cellular_component

A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.

[ "NIF_Subcellular:nlx_subcell_20090702", "PMID:11964142", "PMID:2557062" ]

null

[ "prevacuolar compartment", "PVC" ]

[ "EXACT", "BROAD" ]

[]

[ "NIF_Subcellular:nlx_subcell_20090702" ]

[ "GO:0005768" ]

[]

[ "GO:0005768" ]

[]

null

false

true

2

GO:0005771

5,771

multivesicular body

cellular_component

A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.

[ "PMID:11566881", "PMID:16533950" ]

null

[ "multivesicular endosome", "MVB", "MVE" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "NIF_Subcellular:sao2045955158" ]

[ "GO:0005770" ]

[]

[ "GO:0005770" ]

[]

null

false

true

6

GO:0005773

5,773

vacuole

cellular_component

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or wast...

[ "GOC:mtg_sensu", "ISBN:0198506732" ]

null

[ "vacuolar carboxypeptidase Y" ]

[ "RELATED" ]

[]

[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_flybase_ribbon", "goslim_generic", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_yeast" ]

[ "Wikipedia:Vacuole" ]

[ "GO:0043231" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0043231" ]

[]

null

false

true

5

GO:0005774

5,774

vacuolar membrane

cellular_component

The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

[ "GOC:ai" ]

null

[]

[ "GO:0098588" ]

[ "part_of GO:0005773" ]

[ "part_of" ]

[ "GO:0005773" ]

[ "GO:0005773", "GO:0098588" ]

[]

null

false

true

2

GO:0005775

5,775

vacuolar lumen

cellular_component

The volume enclosed within the vacuolar membrane.

[ "ISBN:0198506732" ]

null

[]

[ "GO:0070013" ]

[ "part_of GO:0005773" ]

[ "part_of" ]

[ "GO:0005773" ]

[ "GO:0005773", "GO:0070013" ]

[ "GO:0031974", "part_of GO:0005773" ]

[]

null

false

true

7

GO:0005776

5,776

autophagosome

cellular_component

A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.

[ "GOC:autophagy", "ISBN:0198547684", "PMID:11099404" ]

null

[ "autophagic vacuole", "initial autophagic vacuole" ]

[ "EXACT", "RELATED" ]

[]

[ "NIF_Subcellular:sao8663416959" ]

[ "GO:0005773" ]

[]

[ "GO:0005773" ]

[]

null

false

true

2

GO:0005777

5,777

peroxisome

cellular_component

A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

[ "GOC:pm", "PMID:9302272", "UniProtKB-KW:KW-0576" ]

null

[ "peroxisomal", "peroxisome vesicle" ]

[ "RELATED", "BROAD" ]

[ "GO:0019818" ]

[ "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_plant", "goslim_plant_ribbon", "goslim_yeast" ]

[ "NIF_Subcellular:sao499555322", "Wikipedia:Peroxisome" ]

[ "GO:0042579" ]

[]

[ "GO:0042579" ]

[]

null

false

true

4

GO:0005778

5,778

peroxisomal membrane

cellular_component

The lipid bilayer surrounding a peroxisome.

[ "GOC:mah" ]

null

[ "peroxisome membrane" ]

[ "EXACT" ]

[]

[ "GO:0031903" ]

[ "part_of GO:0005777" ]

[ "part_of" ]

[ "GO:0005777" ]

[ "GO:0005777", "GO:0031903" ]

[]

null

false

true

1

GO:0005779

5,779

obsolete integral component of peroxisomal membrane

cellular_component

OBSOLETE. The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

[ "GOC:mah" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "integral to peroxisomal membrane" ]

[ "NARROW" ]

[]

[ "GO:0005778" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

null

true

5

GO:0005780

5,780

extrinsic component of intraperoxisomal membrane

cellular_component

The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

[ "GOC:dos", "GOC:jl", "GOC:mah" ]

null

[ "extrinsic to intraperoxisomal membrane", "intra-peroxisomal peripheral membrane" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0031312" ]

[ "part_of GO:0005778" ]

[ "part_of" ]

[ "GO:0005778" ]

[ "GO:0005778", "GO:0031312" ]

[ "GO:0019898", "part_of GO:0005778" ]

[]

null

false

true

2

GO:0005781

5,781

obsolete peroxisome targeting signal receptor complex

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:mah" ]

This term was made obsolete because it represents a single polypeptide rather than a complex; all known peroxisome targeting signal receptors are monomeric.

[ "peroxisome targeting signal receptor complex" ]

[ "EXACT" ]

[]

[ "GO:0000268", "GO:0006625" ]

[]

null

true

6

GO:0005782

5,782

peroxisomal matrix

cellular_component

The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.

[ "GOC:curators", "ISBN:0815316194" ]

null

[ "peroxisomal lumen" ]

[ "EXACT" ]

[ "GO:0031909" ]

[]

[ "GO:0031907" ]

[ "part_of GO:0005777" ]

[ "part_of" ]

[ "GO:0005777" ]

[ "GO:0005777", "GO:0031907" ]

[]

null

false

true

3

GO:0005783

5,783

endoplasmic reticulum

cellular_component

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes ad...

[ "ISBN:0198506732" ]

null

[ "ER" ]

[ "EXACT" ]

[]

[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_yeast" ]

[ "NIF_Subcellular:sao1036339110", "Wikipedia:Endoplasmic_reticulum" ]

[ "GO:0043231" ]

[ "part_of GO:0005737", "part_of GO:0012505" ]

[ "part_of", "part_of" ]

[ "GO:0005737", "GO:0012505" ]

[ "GO:0005737", "GO:0012505", "GO:0043231" ]

[]

null

false

true

4

GO:0005784

5,784

Sec61 translocon complex

cellular_component

A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslatio...

[ "GOC:mah", "PMID:18166647", "PMID:32820719", "PMID:33960686" ]

null

[ "Sec61p-Sbh1p-Sss1p complex" ]

[ "NARROW" ]

[]

[ "GO:0071256" ]

[]

[ "GO:0071256" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22000\" xsd:anyURI" ]

null

false

true

4

GO:0005785

5,785

signal recognition particle receptor complex

cellular_component

A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex.

[ "ISBN:0198506732" ]

null

[ "docking protein complex", "SR complex" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0098796", "GO:0140534" ]

[ "part_of GO:0030867" ]

[ "part_of" ]

[ "GO:0030867" ]

[ "GO:0030867", "GO:0098796", "GO:0140534" ]

[]

null

false

true

8

GO:0005786

5,786

signal recognition particle, endoplasmic reticulum targeting

cellular_component

A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding ...

[ "GOC:mtg_sensu", "ISBN:0198506732" ]

null

[ "signal sequence receptor complex", "SRP" ]

[ "EXACT", "EXACT" ]

[ "GO:0005855" ]

[]

[ "Wikipedia:Signal_recognition_particle" ]

[ "GO:0048500" ]

[]

[ "GO:0048500" ]

[]

null

false

true

1

GO:0005787

5,787

signal peptidase complex

cellular_component

A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.

[ "GOC:sgd_curators", "PMID:1846444", "PMID:7615509" ]

null

[]

[ "GO:0098796", "GO:0140534", "GO:1905370" ]

[ "part_of GO:0005789" ]

[ "part_of" ]

[ "GO:0005789" ]

[ "GO:0005789", "GO:0098796", "GO:0140534", "GO:1905370" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27929\" xsd:anyURI" ]

null

false

true

4

GO:0005788

5,788

endoplasmic reticulum lumen

cellular_component

The volume enclosed by the membranes of the endoplasmic reticulum.

[ "ISBN:0198547684" ]

null

[ "cisternal lumen", "endoplasmic reticulum cisterna", "ER cisterna", "ER lumen" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[ "GO:0016022" ]

[]

[ "GO:0070013" ]

[ "part_of GO:0005783" ]

[ "part_of" ]

[ "GO:0005783" ]

[ "GO:0005783", "GO:0070013" ]

[ "GO:0031974", "part_of GO:0005783" ]

[]

null

false

true

9

GO:0005789

5,789

endoplasmic reticulum membrane

cellular_component

The lipid bilayer surrounding the endoplasmic reticulum.

[ "GOC:mah" ]

null

[ "ER membrane" ]

[ "EXACT" ]

[]

[ "GO:0031090" ]

[ "part_of GO:0042175", "part_of GO:0098827" ]

[ "part_of", "part_of" ]

[ "GO:0042175", "GO:0098827" ]

[ "GO:0031090", "GO:0042175", "GO:0098827" ]

[]

null

false

true

1

GO:0005791

5,791

rough endoplasmic reticulum

cellular_component

The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from th...

[ "ISBN:0198506732" ]

null

[ "RER", "rough ER" ]

[ "EXACT", "EXACT" ]

[]

[ "NIF_Subcellular:sao1881364067", "Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum" ]

[ "GO:0005783" ]

[]

[ "GO:0005783" ]

[]

null

false

true

6

GO:0005792

5,792

obsolete microsome

cellular_component

OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g.

[ "ISBN:0198506732" ]

This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.

[ "microsomal membrane", "microsome" ]

[ "RELATED", "EXACT" ]

[]

[ "Wikipedia:Microsome" ]

[]

[ "GO:0043231" ]

[]

null

true

6

GO:0005793

5,793

endoplasmic reticulum-Golgi intermediate compartment

cellular_component

A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.

[ "GOC:pr", "PMID:16723730" ]

null

[ "EGTC", "endoplasmic reticulum-Golgi transport container", "ER-Golgi intermediate compartment", "ER-Golgi transport container", "ERGIC", "pre-Golgi intermediate compartment", "vesicular-tubular cluster", "VTC" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "Wikipedia:Vesicular-tubular_cluster" ]

[ "GO:0043231" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0043231" ]

[]

null

false

true

2

GO:0005794

5,794

Golgi apparatus

cellular_component

A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic p...

[ "ISBN:0198506732", "PMID:9695800" ]

Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, w...

[ "Golgi", "Golgi complex", "Golgi ribbon" ]

[ "BROAD", "EXACT", "NARROW" ]

[]

[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_yeast" ]

[ "NIF_Subcellular:sao451912436", "Wikipedia:Golgi_apparatus" ]

[ "GO:0043231" ]

[ "part_of GO:0005737", "part_of GO:0012505" ]

[ "part_of", "part_of" ]

[ "GO:0005737", "GO:0012505" ]

[ "GO:0005737", "GO:0012505", "GO:0043231" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14798\" xsd:anyURI" ]

null

false

true

7

GO:0005795

5,795

Golgi stack

cellular_component

The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.

[ "GOC:mah", "ISBN:0815316194" ]

null

[ "dictyosome", "Golgi cisternae" ]

[ "NARROW", "EXACT" ]

[ "GO:0016940" ]

[]

[ "GO:0098791" ]

[]

[ "GO:0098791" ]

[]

null

false

true

3

GO:0005796

5,796

Golgi lumen

cellular_component

The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.

[ "GOC:mah" ]

null

[ "Golgi apparatus lumen" ]

[ "EXACT" ]

[]

[ "GO:0070013" ]

[ "part_of GO:0005794" ]

[ "part_of" ]

[ "GO:0005794" ]

[ "GO:0005794", "GO:0070013" ]

[]

null

false

true

3

GO:0005797

5,797

Golgi medial cisterna

cellular_component

The middle Golgi cisterna (or cisternae).

[ "ISBN:0815316194" ]

null

[ "Golgi apparatus medial cisterna" ]

[ "EXACT" ]

[]

[ "GO:0031985" ]

[]

[ "GO:0031985" ]

[]

null

false

true

2

GO:0005800

5,800

obsolete COPII vesicle

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.

[ "COPII vesicle" ]

[ "EXACT" ]

[]

[ "GO:0030134" ]

[]

null

true

2

GO:0005801

5,801

cis-Golgi network

cellular_component

The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.

[ "ISBN:0198506732", "ISBN:0815316194", "PMID:23543640", "PMID:9695800" ]

The CGN is not considered part of the Golgi stack.

[ "cis face", "cis Golgi network", "forming face", "Golgi cis face", "Golgi cis-face" ]

[ "BROAD", "EXACT", "RELATED", "RELATED", "RELATED" ]

[]

[ "NIF_Subcellular:sao632188024" ]

[ "GO:0043231" ]

[ "part_of GO:0005794" ]

[ "part_of" ]

[ "GO:0005794" ]

[ "GO:0005794", "GO:0043231" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14798\" xsd:anyURI" ]

null

false

true

3

GO:0005802

5,802

trans-Golgi network

cellular_component

The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and...

[ "GOC:vw", "ISBN:0815316194", "PMID:9695800" ]

There are different opinions about whether the TGN should be considered part of the Golgi apparatus or not. We follow Alberts et al, 1994 (ISBN:0815316194), who consider it to be a part.

[ "Golgi trans face", "Golgi trans-face", "late Golgi", "maturing face", "TGN", "trans face", "trans Golgi network" ]

[ "RELATED", "RELATED", "RELATED", "RELATED", "EXACT", "BROAD", "EXACT" ]

[]

[ "NIF_Subcellular:sao9456487" ]

[ "GO:0098791" ]

[]

[ "GO:0098791" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14798\" xsd:anyURI" ]

null

false

true

5

GO:0005803

5,803

obsolete secretory vesicle

cellular_component

OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.

[ "ISBN:0198547684" ]

This term was made obsolete because it was being used to describe two different components.

[ "secretory vesicle", "transition vesicle" ]

[ "EXACT", "NARROW" ]

[]

[ "GO:0030133", "GO:0030141" ]

[]

null

true

8

GO:0005804

5,804

obsolete secretory vesicle membrane

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because its parent was made obsolete.

[ "secretory vesicle membrane" ]

[ "EXACT" ]

[]

[ "GO:0030658", "GO:0030667" ]

[]

null

true

8

GO:0005805

5,805

obsolete ER-Golgi transport vesicle

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.

[ "ER-Golgi transport vesicle" ]

[ "EXACT" ]

[]

[ "GO:0030134" ]

[]

null

true

9

GO:0005806

5,806

obsolete Golgi-ER transport vesicle

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.

[ "Golgi-ER transport vesicle" ]

[ "EXACT" ]

[]

[ "GO:0030142" ]

[]

null

true

9

GO:0005808

5,808

obsolete Golgi-plasma membrane transport vesicle

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; a personal communication from John Armstrong indicated that a replacement term was not required, as TGN-Golgi transport is likely to be mediated by tubules rather than vesicles.

[ "Golgi-plasma membrane transport vesicle" ]

[ "EXACT" ]

[]

[ "GO:0030133" ]

[]

null

true

6

GO:0005809

5,809

obsolete Golgi-vacuole transport vesicle

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.

[ "Golgi-vacuole transport vesicle" ]

[ "EXACT" ]

[]

[ "GO:0030133" ]

[]

null

true

6

GO:0005810

5,810

obsolete endocytotic transport vesicle

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.

[ "endocytotic transport vesicle" ]

[ "EXACT" ]

[]

[ "GO:0030139" ]

[]

null

true

9

GO:0005811

5,811

lipid droplet

cellular_component

An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.

[ "GOC:mah", "GOC:tb" ]

Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers.

[ "adiposome", "lipid body", "lipid particle" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "goslim_chembl", "goslim_generic" ]

[]

[ "GO:0043232" ]

[]

[ "GO:0043232" ]

[]

null

false

true

2

GO:0005813

5,813

centrosome

cellular_component

A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continuall...

[ "GOC:mah", "ISBN:0198547684" ]

null

[]

[ "goslim_pir" ]

[ "Wikipedia:Centrosome" ]

[ "GO:0005815" ]

[ "has_part GO:0005814" ]

[ "has_part" ]

[ "GO:0005814" ]

[ "GO:0005814", "GO:0005815" ]

[]

null

false

true

1

GO:0005814

5,814

centriole

cellular_component

A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete mic...

[ "ISBN:0198547684" ]

In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain differ...

[ "daughter centriole", "mother centriole" ]

[ "NARROW", "NARROW" ]

[]

[ "NIF_Subcellular:sao95019936", "Wikipedia:Centriole" ]

[ "GO:0043232" ]

[ "part_of GO:0005815" ]

[ "part_of" ]

[ "GO:0005815" ]

[ "GO:0005815", "GO:0043232" ]

[]

null

false

true

8

GO:0005815

5,815

microtubule organizing center

cellular_component

An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

[ "GOC:vw", "ISBN:0815316194", "PMID:17072892", "PMID:17245416", "Wikipedia:Microtubule_organizing_center" ]

null

[ "microtubule organising centre", "MTOC" ]

[ "EXACT", "EXACT" ]

[]

[ "goslim_candida", "goslim_chembl", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_yeast" ]

[ "Wikipedia:Microtubule_organizing_center" ]

[ "GO:0110165" ]

[ "part_of GO:0015630" ]

[ "part_of" ]

[ "GO:0015630" ]

[ "GO:0015630", "GO:0110165" ]

[]

null

false

true

7

GO:0005816

5,816

spindle pole body

cellular_component

The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.

[ "ISBN:0879693568" ]

null

[ "SPB" ]

[ "EXACT" ]

[]

[ "Wikipedia:Spindle_pole_body" ]

[ "GO:0005815" ]

[]

[ "GO:0005815" ]

[]

null

false

true

4

GO:0005819

5,819

spindle

cellular_component

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

[ "ISBN:0198547684" ]

null

[]

[ "Wikipedia:Spindle_apparatus" ]

[ "GO:0043232" ]

[ "part_of GO:0015630" ]

[ "part_of" ]

[ "GO:0015630" ]

[ "GO:0015630", "GO:0043232" ]

[]

null

false

true

9

GO:0005821

5,821

intermediate layer of spindle pole body

cellular_component

Structure between the central and outer plaques of the spindle pole body.

[ "PMID:9215630" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0005816" ]

[ "part_of" ]

[ "GO:0005816" ]

[ "GO:0005816", "GO:0110165" ]

[]

null

false

true

1

GO:0005822

5,822

inner plaque of spindle pole body

cellular_component

One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus.

[ "ISBN:0879693568" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0005816" ]

[ "part_of" ]

[ "GO:0005816" ]

[ "GO:0005816", "GO:0110165" ]

[]

null

false

true

9

GO:0005823

5,823

central plaque of spindle pole body

cellular_component

One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope.

[ "ISBN:0879693568" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0005816" ]

[ "part_of" ]

[ "GO:0005816" ]

[ "GO:0005816", "GO:0110165" ]

[]

null

false

true

6

GO:0005825

5,825

half bridge of spindle pole body

cellular_component

Structure adjacent to the plaques of the spindle pole body.

[ "ISBN:0879693568" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0005816" ]

[ "part_of" ]

[ "GO:0005816" ]

[ "GO:0005816", "GO:0110165" ]

[]

null

false

true

8

GO:0005826

5,826

actomyosin contractile ring

cellular_component

A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In bud...

[ "GOC:expert_jrp", "GOC:sgd_curators", "GOC:vw", "ISBN:0805319409", "ISBN:0815316194", "PMID:28914606" ]

null

[ "actomyosin ring", "CAR", "constriction ring", "contractile actomyosin ring", "cytokinetic ring" ]

[ "RELATED", "EXACT", "RELATED", "EXACT", "RELATED" ]

[ "GO:0030480" ]

[]

[ "GO:0070938" ]

[ "part_of GO:0030864", "part_of GO:0032153" ]

[ "part_of", "part_of" ]

[ "GO:0030864", "GO:0032153" ]

[ "GO:0030864", "GO:0032153", "GO:0070938" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14337\" xsd:anyURI" ]

null

false

true

3

GO:0005827

5,827

polar microtubule

cellular_component

Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart.

[ "ISBN:0815316194" ]

null

[ "pole-to-pole microtubule" ]

[ "EXACT" ]

[]

[ "GO:0005876" ]

[ "part_of GO:0000922" ]

[ "part_of" ]

[ "GO:0000922" ]

[ "GO:0000922", "GO:0005876" ]

[ "GO:0005876", "part_of GO:0000922" ]

[]

null

false

true

3

GO:0005828

5,828

kinetochore microtubule

cellular_component

Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.

[ "ISBN:0815316194" ]

null

[ "pole-to-kinetochore microtubule" ]

[ "EXACT" ]

[]

[ "GO:0005876" ]

[]

[ "GO:0005876" ]

[]

null

false

true

1

GO:0005829

5,829

cytosol

cellular_component

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

[ "GOC:hjd", "GOC:jl" ]

null

[]

[ "goslim_agr", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_flybase_ribbon", "goslim_generic", "goslim_mouse", "goslim_plant" ]

[ "NIF_Subcellular:sao101633890", "Wikipedia:Cytosol" ]

[ "GO:0110165" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0110165" ]

[]

null

false

true

8

GO:0005831

5,831

steroid hormone aporeceptor complex

cellular_component

A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand.

[ "PMID:7493981" ]

null

[]

[ "GO:0032991" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:0032991" ]

[]

null

false

true

7

GO:0005832

5,832

chaperonin-containing T-complex

cellular_component

A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.

[ "GOC:sgd_curators", "PMID:11580267" ]

null

[ "CCT particle", "TriC" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0101031" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:0101031" ]

[]

null

false

true

6

GO:0005833

5,833

hemoglobin complex

cellular_component

An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group.

[ "GOC:jl", "ISBN:0198506732" ]

null

[ "haemoglobin complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:0032991" ]

[]

null

false

true

7

GO:0005834

5,834

heterotrimeric G-protein complex

cellular_component

Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the b...

[ "ISBN:0198547684" ]

See also the molecular function term 'G protein-coupled receptor activity ; GO:0004930'.

[ "heterotrimeric G-protein GTPase activity", "heterotrimeric G-protein GTPase, alpha-subunit", "heterotrimeric G-protein GTPase, beta-subunit", "heterotrimeric G-protein GTPase, gamma-subunit" ]

[ "RELATED", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0098797", "GO:1905360" ]

[ "part_of GO:0031234" ]

[ "part_of" ]

[ "GO:0031234" ]

[ "GO:0031234", "GO:0098797", "GO:1905360" ]

[]

null

false

true

9

GO:0005835

5,835

fatty acid synthase complex

cellular_component

A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.

[ "GOC:pde", "GOC:sgd_curators", "ISBN:0716746840" ]

null

[ "cytosolic FAS complex", "cytosolic fatty acid synthase complex", "cytosolic type I FAS complex", "cytosolic type I fatty acid synthase complex", "FAS complex", "fatty acid synthetase complex", "holo-[acyl-carrier-protein] synthase complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "RELATED" ]

[ "GO:0031373", "GO:0031374" ]

[ "goslim_pir" ]

[ "Wikipedia:Fatty_acid_synthetase_complex" ]

[ "GO:0140535", "GO:1902494" ]

[]

[ "GO:0140535", "GO:1902494" ]

[]

null

false

true

8

GO:0005836

5,836

fatty-acyl-CoA synthase complex

cellular_component

A protein complex that possesses fatty-acyl-CoA synthase activity.

[ "GOC:mah" ]

Note that fatty acid synthetases of vertebrates and yeast are stable enzyme complexes of multifunctional polypeptide chains, whereas the fatty acid synthetases of plants and E. coli consist of non-associated individual enzymes.

[ "fatty acyl CoA synthase complex" ]

[ "EXACT" ]

[]

[ "GO:1990234" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1990234" ]

[]

null

false

true

8

GO:0005837

5,837

obsolete 26S proteasome

cellular_component

OBSOLETE. A large multisubunit protease found in the cytosol that recognizes, unfolds, and digests protein substrates that have been marked for degradation by the attachment of a ubiquitin group. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: the ATP-dependent 19S caps are...

[ "PMID:10410804" ]

This term was made obsolete because its definition was inaccurate.

[ "26S proteasome" ]

[ "EXACT" ]

[]

[ "GO:0000502" ]

[]

null

true

4

GO:0005838

5,838

proteasome regulatory particle

cellular_component

A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.

[ "GOC:mtg_sensu", "GOC:rb" ]

null

[ "19S regulatory particle", "modulator complex", "PA700 proteasome activator", "PA700-dependent proteasome activator" ]

[ "NARROW", "RELATED", "NARROW", "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0022624" ]

[ "part_of" ]

[ "GO:0022624" ]

[ "GO:0022624", "GO:0032991" ]

[]

null

false

true

5

GO:0005839

5,839

proteasome core complex

cellular_component

A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.

[ "GOC:rb", "PMID:10806206" ]

null

[ "20S core complex", "20S proteasome", "macropain", "PA28gamma-20S proteasome" ]

[ "NARROW", "NARROW", "EXACT", "NARROW" ]

[ "GO:0000503" ]

[ "goslim_metagenomics" ]

[]

[ "GO:0140535", "GO:1902494" ]

[ "part_of GO:0000502" ]

[ "part_of" ]

[ "GO:0000502" ]

[ "GO:0000502", "GO:0140535", "GO:1902494" ]

[]

null

false

true

5

GO:0005840

5,840

ribosome

cellular_component

An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized ...

[ "ISBN:0198506732" ]

null

[ "free ribosome", "membrane bound ribosome", "ribosomal RNA" ]

[ "NARROW", "NARROW", "RELATED" ]

[ "GO:0033279" ]

[ "goslim_candida", "goslim_chembl", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_metagenomics", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_prokaryote", "goslim_prokaryote_ribbon", "goslim_yeast" ]

[ "NIF_Subcellular:sao1429207766", "Wikipedia:Ribosome" ]

[ "GO:0043232" ]

[]

[ "GO:0043232" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17777\" xsd:anyURI" ]

null

false

true

2

GO:0005844

5,844

obsolete polysome

cellular_component

OBSOLETE. A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.

[ "ISBN:0198506732", "NIF_Subcellular:sao1038025871" ]

The reason for obsoletion is that the term is out of scope for GO.

[ "polyribosome" ]

[ "EXACT" ]

[]

[ "NIF_Subcellular:sao1038025871", "Wikipedia:Polysome" ]

[]

[ "GO:0005840" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24651\" xsd:anyURI" ]

null

true

7

GO:0005845

5,845

obsolete mRNA cap binding complex

cellular_component

OBSOLETE. Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.

[ "GOC:jid" ]

The reason for obsoletion is that this term was an unnecessary grouping term.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26347\" xsd:anyURI" ]

null

true

2

GO:0005847

5,847

mRNA cleavage and polyadenylation specificity factor complex

cellular_component

A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.

[ "PMID:14749727" ]

null

[ "CFII complex", "cleavage and polyadenylylation specificity factor activity", "CPF complex", "CPSF complex" ]

[ "RELATED", "RELATED", "NARROW", "NARROW" ]

[]

[ "GO:0005849" ]

[]

[ "GO:0005849" ]

[]

null

false

true

1

GO:0005848

5,848

mRNA cleavage stimulating factor complex

cellular_component

A protein complex required for mRNA cleavage but not for poly(A) addition.

[ "GOC:mah", "PMID:10357856" ]

null

[ "cleavage stimulation factor activity", "CstF complex" ]

[ "RELATED", "NARROW" ]

[]

[ "GO:0005849" ]

[]

[ "GO:0005849" ]

[]

null

false

true

6

GO:0005850

5,850

eukaryotic translation initiation factor 2 complex

cellular_component

Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.

[ "PMID:10216940" ]

null

[ "eIF-2", "eIF2" ]

[ "EXACT", "EXACT" ]

[]

[ "Wikipedia:EIF-2" ]

[ "GO:0032991" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0032991" ]

[]

null

false

true

2

GO:0005852

5,852

eukaryotic translation initiation factor 3 complex

cellular_component

A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex....

[ "PMID:15904532" ]

null

[ "eIF-3", "eIF3" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0032991" ]

[]

null

false

true

6

GO:0005853

5,853

eukaryotic translation elongation factor 1 complex

cellular_component

A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.

[ "GOC:jl", "PMID:10216950" ]

null

[]

[ "GO:0032991" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0032991" ]

[]

null

false

true

7