go_id string | go_numeric_id int64 | name string | namespace string | definition string | definition_xrefs list | comment string | synonyms list | synonym_scopes list | alt_ids list | subsets list | xrefs list | is_a_ids list | relationship_edges list | relationship_types list | relationship_target_ids list | parent_ids list | intersection_of list | union_of list | disjoint_from list | replaced_by list | consider list | property_values list | created_by string | creation_date string | is_obsolete bool | in_go_basic bool | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GO:0006500 | 6,500 | N-terminal protein palmitoylation | biological_process | The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein. | [
"GOC:mah"
] | null | [] | [] | [] | [
"gocheck_obsoletion_candidate"
] | [] | [
"GO:0006498",
"GO:0018345"
] | [] | [] | [] | [
"GO:0006498",
"GO:0018345"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006501 | 6,501 | C-terminal protein lipidation | biological_process | The covalent attachment of a lipid group to the carboxy-terminus of a protein. | [
"GOC:jl"
] | null | [] | [] | [] | [
"gocheck_obsoletion_candidate"
] | [
"Reactome:R-HSA-163125 \"Post-translational modification: synthesis of GPI-anchored proteins\""
] | [
"GO:0006497",
"GO:0018410"
] | [] | [] | [] | [
"GO:0006497",
"GO:0018410"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006502 | 6,502 | obsolete C-terminal protein prenylation | biological_process | OBSOLETE. The covalent or non-covalent attachment of a prenyl group to the carboxy-terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added. | [
"GOC:jl"
] | This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein. | [
"C-terminal protein prenylation"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0018342"
] | [] | [] | null | null | true | true | 6 |
GO:0006503 | 6,503 | obsolete C-terminal protein farnesylation | biological_process | OBSOLETE. The covalent or non-covalent attachment of a farnesyl group to the carboxy terminus of a protein. | [
"GOC:jl"
] | This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein. | [
"C-terminal protein farnesylation"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0018343"
] | [] | [] | null | null | true | true | 6 |
GO:0006504 | 6,504 | obsolete C-terminal protein geranylgeranylation | biological_process | OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy-terminus of a protein. | [
"GOC:jl"
] | This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein. | [
"C-terminal protein geranylgeranylation"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0018344"
] | [] | [] | null | null | true | true | 7 |
GO:0006505 | 6,505 | GPI anchor metabolic process | biological_process | The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain.... | [
"ISBN:0198506732"
] | null | [
"glycosylphosphatidylinositol metabolic process",
"glycosylphosphatidylinositol metabolism",
"GPI anchor metabolism",
"GPI/GSI anchor metabolic process",
"GPI/GSI anchor metabolism"
] | [
"EXACT",
"EXACT",
"EXACT",
"BROAD",
"BROAD"
] | [
"GO:0046472"
] | [] | [] | [
"GO:0006650",
"GO:0006664"
] | [] | [] | [] | [
"GO:0006650",
"GO:0006664"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0006506 | 6,506 | GPI anchor biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked t... | [
"GOC:curators",
"ISBN:0198547684"
] | null | [
"glycosylphosphatidylinositol biosynthesis",
"glycosylphosphatidylinositol biosynthetic process",
"GPI anchor anabolism",
"GPI anchor biosynthesis",
"GPI anchor formation",
"GPI anchor synthesis",
"GPI/GSI anchor biosynthesis",
"GPI/GSI anchor biosynthetic process"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"BROAD",
"BROAD"
] | [
"GO:0015998"
] | [] | [
"MetaCyc:PWY-8600",
"MetaCyc:PWY-8601",
"Reactome:R-HSA-162710 \"Synthesis of glycosylphosphatidylinositol (GPI)\""
] | [
"GO:0006505",
"GO:0009247",
"GO:0046474"
] | [
"part_of GO:0180046"
] | [
"part_of"
] | [
"GO:0180046"
] | [
"GO:0006505",
"GO:0009247",
"GO:0046474",
"GO:0180046"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PWY-8600",
"skos:narrowMatch MetaCyc:PWY-8601",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28227\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30568\" xsd:anyURI"
] | null | null | false | true | 9 |
GO:0006508 | 6,508 | proteolysis | biological_process | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. | [
"GOC:bf",
"GOC:mah"
] | This term was intentionally placed under 'protein metabolic process ; GO:0019538' rather than 'protein catabolic process ; GO:0030163' to cover all processes centered on breaking peptide bonds, including those involved in protein processing. | [
"ATP-dependent proteolysis",
"peptidolysis"
] | [
"NARROW",
"EXACT"
] | [] | [
"goslim_chembl",
"goslim_metagenomics",
"goslim_pir"
] | [
"Wikipedia:Proteolysis"
] | [
"GO:0019538"
] | [] | [] | [] | [
"GO:0019538"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0006509 | 6,509 | membrane protein ectodomain proteolysis | biological_process | The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). | [
"GOC:jl",
"PMID:24227200"
] | null | [
"ectoderm shedding",
"ectodomain cleavage",
"membrane protein solubilization",
"receptor shedding"
] | [
"BROAD",
"EXACT",
"RELATED",
"RELATED"
] | [] | [] | [] | [
"GO:0033619"
] | [] | [] | [] | [
"GO:0033619"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0006510 | 6,510 | obsolete ATP-dependent proteolysis | biological_process | OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein using energy from the hydrolysis of ATP. | [
"GOC:jl"
] | This term was made obsolete because it represents a molecular function. | [
"ATP-dependent peptidolysis",
"ATP-dependent proteolysis"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0006508",
"GO:0016485",
"GO:0030163"
] | [] | null | null | true | true | 7 |
GO:0006511 | 6,511 | ubiquitin-dependent protein catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. | [
"GOC:curators"
] | null | [
"myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown",
"myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process",
"myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism",
"myofibrillar protein ubiquitination during ubiqu... | [
"NARROW",
"NARROW",
"NARROW",
"NARROW",
"BROAD",
"NARROW",
"RELATED",
"NARROW",
"NARROW",
"RELATED",
"NARROW",
"NARROW",
"NARROW",
"NARROW",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [
"GO:0042787",
"GO:0043432"
] | [] | [] | [
"GO:0019941"
] | [
"has_part GO:0016567"
] | [
"has_part"
] | [
"GO:0016567"
] | [
"GO:0016567",
"GO:0019941"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0006512 | 6,512 | obsolete ubiquitin cycle | biological_process | OBSOLETE. The cyclical process by which one or more ubiquitin groups are added to (ubiquitination) and removed from (deubiquitination) a protein. | [
"PMID:11917093"
] | This term was made obsolete because it implies that every protein that is ubiquitinated is also subsequently deubiquinitated, which is not true. Also, the process ontology does not include analogous terms for other small modifiers. | [
"ubiquitin cycle"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | null | null | true | true | 5 |
GO:0006513 | 6,513 | protein monoubiquitination | biological_process | Addition of a single ubiquitin group to a protein. | [
"GOC:ai"
] | null | [
"protein monoubiquitinylation",
"protein monoubiquitylation"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0016567"
] | [] | [] | [] | [
"GO:0016567"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0006516 | 6,516 | glycoprotein catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. | [
"GOC:curators",
"ISBN:0198506732"
] | null | [
"glycoprotein breakdown",
"glycoprotein catabolism",
"glycoprotein degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0009100",
"GO:0030163",
"GO:1901136"
] | [] | [] | [] | [
"GO:0009100",
"GO:0030163",
"GO:1901136"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0006517 | 6,517 | protein deglycosylation | biological_process | The removal of sugar residues from a glycosylated protein. | [
"GOC:mah"
] | null | [
"glycoprotein deglycosylation"
] | [
"EXACT"
] | [] | [
"gocheck_obsoletion_candidate"
] | [] | [
"GO:0009100",
"GO:0036211"
] | [] | [] | [] | [
"GO:0009100",
"GO:0036211"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0006518 | 6,518 | peptide metabolic process | biological_process | The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. | [
"GOC:curators"
] | null | [
"peptide metabolism"
] | [
"EXACT"
] | [] | [
"goslim_pir"
] | [
"Reactome:R-HSA-2980736 \"Peptide hormone metabolism\""
] | [
"GO:0008152"
] | [] | [] | [] | [
"GO:0008152"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0006520 | 6,520 | amino acid metabolic process | biological_process | The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. | [
"ISBN:0198506732"
] | null | [
"amino acid and derivative metabolism",
"cellular amino acid and derivative metabolic process",
"cellular amino acid metabolic process",
"cellular amino acid metabolism"
] | [
"RELATED",
"RELATED",
"EXACT",
"EXACT"
] | [
"GO:0006519"
] | [
"goslim_chembl",
"goslim_drosophila",
"goslim_generic",
"goslim_pir",
"goslim_pombe",
"goslim_prokaryote",
"goslim_prokaryote_ribbon",
"goslim_yeast"
] | [] | [
"GO:0044238"
] | [] | [] | [] | [
"GO:0044238"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17904\" xsd:anyURI"
] | null | null | false | true | 4 |
GO:0006523 | 6,523 | alanine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid. | [
"GOC:curators"
] | null | [
"alanine anabolism",
"alanine biosynthesis",
"alanine formation",
"alanine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:1901607"
] | [] | [] | [] | [
"GO:1901607"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0006524 | 6,524 | obsolete alanine catabolic process | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid. | [
"GOC:curators"
] | The reason for obsoletion is that a more specific term has been created. | [
"alanine breakdown",
"alanine catabolism",
"alanine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0042853"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31068\" xsd:anyURI"
] | null | null | true | true | 9 |
GO:0006525 | 6,525 | arginine metabolic process | biological_process | The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. | [
"GOC:curators"
] | null | [
"arginine metabolism"
] | [
"EXACT"
] | [] | [] | [
"Wikipedia:Arginine"
] | [
"GO:1901605"
] | [] | [] | [] | [
"GO:1901605"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0006526 | 6,526 | L-arginine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. | [
"ISBN:0198506732"
] | null | [
"arginine anabolism",
"arginine biosynthesis",
"arginine formation",
"arginine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:ARGSYN-PWY",
"MetaCyc:ARGSYNBSUB-PWY",
"MetaCyc:PWY-5154",
"MetaCyc:PWY-7400"
] | [
"GO:0006525",
"GO:0009084"
] | [] | [] | [] | [
"GO:0006525",
"GO:0009084"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:ARGSYN-PWY",
"skos:narrowMatch MetaCyc:ARGSYNBSUB-PWY",
"skos:narrowMatch MetaCyc:PWY-5154",
"skos:narrowMatch MetaCyc:PWY-7400",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28527\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-o... | null | null | false | true | 9 |
GO:0006527 | 6,527 | L-arginine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-arginine. | [
"GOC:curators"
] | null | [
"arginine breakdown",
"arginine catabolism",
"arginine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:ARG-GLU-PWY",
"MetaCyc:ARG-PRO-PWY",
"MetaCyc:ARGASEDEG-PWY",
"MetaCyc:ARGDEG-III-PWY",
"MetaCyc:ARGDEG-IV-PWY",
"MetaCyc:ARGDEG-V-PWY",
"MetaCyc:ARGDEGRAD-PWY",
"MetaCyc:AST-PWY",
"MetaCyc:PWY-5024",
"MetaCyc:PWY-5742",
"MetaCyc:PWY-6344",
"MetaCyc:PWY-7523",
"MetaCyc:PWY-8187",
... | [
"GO:0006525",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006525",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:ARG-GLU-PWY",
"skos:narrowMatch MetaCyc:ARG-PRO-PWY",
"skos:narrowMatch MetaCyc:ARGASEDEG-PWY",
"skos:narrowMatch MetaCyc:ARGDEG-III-PWY",
"skos:narrowMatch MetaCyc:ARGDEG-IV-PWY",
"skos:narrowMatch MetaCyc:ARGDEG-V-PWY",
"skos:narrowMatch MetaCyc:ARGDEGRAD-PWY",
"skos:narrow... | null | null | false | true | 5 |
GO:0006528 | 6,528 | asparagine metabolic process | biological_process | The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid. | [
"GOC:curators"
] | null | [
"asparagine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0019752"
] | [] | [] | [] | [
"GO:0019752"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006529 | 6,529 | obsolete asparagine biosynthetic process | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid. | [
"GOC:curators"
] | The reason for obsoletion is that more specific terms were created. | [
"asparagine anabolism",
"asparagine biosynthesis",
"asparagine formation",
"asparagine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0070981"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29444\" xsd:anyURI"
] | null | null | true | true | 8 |
GO:0006531 | 6,531 | aspartate metabolic process | biological_process | The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. | [
"GOC:curators",
"ISBN:0198506732"
] | null | [
"aspartate metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0043648",
"GO:1901605"
] | [] | [] | [] | [
"GO:0043648",
"GO:1901605"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006532 | 6,532 | L-aspartate biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. | [
"GOC:curators",
"ISBN:0198506732",
"MetaCyc:ASPARTATESYN-PWY"
] | null | [
"aspartate anabolism",
"aspartate biosynthesis",
"aspartate formation",
"aspartate synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:ASPARTATESYN-PWY"
] | [
"GO:0006531",
"GO:0009067",
"GO:0043650"
] | [] | [] | [] | [
"GO:0006531",
"GO:0009067",
"GO:0043650"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch MetaCyc:ASPARTATESYN-PWY"
] | null | null | false | true | 3 |
GO:0006534 | 6,534 | obsolete cysteine metabolic process | biological_process | OBSOLETE. The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid. | [
"GOC:curators"
] | This term was obsoleted because it is an unnecessary grouping term. | [
"cysteine metabolism"
] | [
"EXACT"
] | [] | [] | [
"Wikipedia:Cysteine_metabolism"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0019344",
"GO:0019448"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31281\" xsd:anyURI"
] | null | null | true | true | 6 |
GO:0006535 | 6,535 | obsolete L-cysteine biosynthetic process from L-serine | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the formation of cysteine from L- serine. | [
"GOC:curators"
] | This term was obsoleted because it is too specific and is outside the scope of GO. | [
"cysteine anabolism from serine",
"cysteine formation from serine",
"cysteine synthesis from serine"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0019344"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30758\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31281\" xsd:anyURI"
] | null | null | true | true | 8 |
GO:0006536 | 6,536 | glutamate metabolic process | biological_process | The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. | [
"GOC:curators"
] | null | [
"glutamate metabolism",
"glutamic acid metabolic process",
"glutamic acid metabolism"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"Wikipedia:Glutamic_acid"
] | [
"GO:0043648",
"GO:1901605"
] | [] | [] | [] | [
"GO:0043648",
"GO:1901605"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0006537 | 6,537 | obsolete glutamate biosynthetic process | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid. | [
"GOC:curators"
] | This is a duplicate term. | [
"glutamate anabolism",
"glutamate biosynthesis",
"glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)",
"glutamate biosynthesis, using glutamate synthase (NADPH)",
"glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)",
"glutamate biosynthetic process, using glutamate syntha... | [
"EXACT",
"EXACT",
"NARROW",
"NARROW",
"NARROW",
"NARROW",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0097054"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31068\" xsd:anyURI"
] | null | null | true | true | 4 |
GO:0006538 | 6,538 | L-glutamate catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-glutamate. | [
"GOC:curators"
] | null | [
"glutamate breakdown",
"glutamate catabolism",
"glutamate deamidation",
"glutamate degradation",
"glutamic acid catabolic process",
"glutamic acid catabolism"
] | [
"EXACT",
"EXACT",
"RELATED",
"EXACT",
"EXACT",
"EXACT"
] | [
"GO:0019459"
] | [] | [
"MetaCyc:GLUTAMATE-DEG1-PWY",
"MetaCyc:GLUTDEG-PWY",
"MetaCyc:PWY-5766",
"MetaCyc:PWY0-1305"
] | [
"GO:0006536",
"GO:0043649",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006536",
"GO:0043649",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:GLUTAMATE-DEG1-PWY",
"skos:narrowMatch MetaCyc:GLUTDEG-PWY",
"skos:narrowMatch MetaCyc:PWY-5766",
"skos:narrowMatch MetaCyc:PWY0-1305",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontolog... | null | null | false | true | 8 |
GO:0006539 | 6,539 | obsolete glutamate catabolic process via 2-oxoglutarate | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate. | [
"GOC:curators"
] | This term was obsoleted because it represents a specific instance of a pathway that should be captured as a GO-CAM model. | [
"glutamate breakdown via 2-oxoglutarate",
"glutamate catabolic process via 2-ketoglutarate",
"glutamate catabolic process via alpha-ketoglutarate",
"glutamate catabolic process via alpha-oxoglutarate",
"glutamate catabolism via 2-ketoglutarate",
"glutamate catabolism via alpha-ketoglutarate",
"glutamate... | [
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28390\" xsd:anyURI"
] | null | null | true | true | 8 |
GO:0006540 | 6,540 | GABA shunt | biological_process | The chemical reactions and pathways resulting in the formation of succinate from L-glutamate via gamma-aminobutyrate (GABA), bypassing two steps of the TCA cycle. It operates through the sequential conversion of glutamate to GABA by glutamate decarboxylase, transamination of GABA to succinic semialdehyde by GABA transa... | [
"PMID:39703920"
] | null | [
"4-aminobutyrate shunt",
"gamma aminobutyrate shunt",
"gamma-aminobutyrate shunt",
"glutamate decarboxylation to succinate"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:GLUDEG-I-PWY",
"MetaCyc:PWY-8346"
] | [
"GO:0006105",
"GO:0006536",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0006105",
"GO:0006536",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:GLUDEG-I-PWY",
"skos:narrowMatch MetaCyc:PWY-8346",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28355\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28802\" xsd:anyURI",
"term_tracker_item \"https://github.com/gene... | null | null | false | true | 1 |
GO:0006541 | 6,541 | L-glutamine metabolic process | biological_process | The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. | [
"GOC:ai"
] | null | [
"glutamine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0006542 | 6,542 | obsolete glutamine biosynthetic process | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid. | [
"GOC:ai"
] | This is a duplicate term. | [
"glutamine anabolism",
"glutamine biosynthesis",
"glutamine formation",
"glutamine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:PWY-6549"
] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:1901704"
] | [] | [
"skos:narrowMatch MetaCyc:PWY-6549",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31068\" xsd:anyURI"
] | null | null | true | true | 6 |
GO:0006543 | 6,543 | L-glutamine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-glutamine. | [
"GOC:curators"
] | null | [
"glutamine breakdown",
"glutamine catabolism",
"glutamine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:GLUTAMINDEG-PWY",
"MetaCyc:GLUTAMINEFUM-PWY"
] | [
"GO:0006541",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006541",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:GLUTAMINDEG-PWY",
"skos:narrowMatch MetaCyc:GLUTAMINEFUM-PWY",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28154\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tracker_item \"https://gith... | null | null | false | true | 6 |
GO:0006544 | 6,544 | glycine metabolic process | biological_process | The chemical reactions and pathways involving glycine, aminoethanoic acid. | [
"GOC:curators"
] | null | [
"glycine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0170039",
"GO:1901605"
] | [] | [] | [] | [
"GO:0170039",
"GO:1901605"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0006545 | 6,545 | glycine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid. | [
"GOC:curators",
"MetaCyc:GLYCINE-SYN2-PWY"
] | null | [
"glycine anabolism",
"glycine biosynthesis",
"glycine formation",
"glycine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:GLYCINE-SYN2-PWY",
"MetaCyc:GLYSYN-ALA-PWY",
"MetaCyc:GLYSYN-PWY",
"MetaCyc:GLYSYN-THR-PWY",
"MetaCyc:PWY-8551"
] | [
"GO:0006544",
"GO:0009070",
"GO:0170038"
] | [] | [] | [] | [
"GO:0006544",
"GO:0009070",
"GO:0170038"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:GLYCINE-SYN2-PWY",
"skos:narrowMatch MetaCyc:GLYSYN-ALA-PWY",
"skos:narrowMatch MetaCyc:GLYSYN-PWY",
"skos:narrowMatch MetaCyc:GLYSYN-THR-PWY",
"skos:narrowMatch MetaCyc:PWY-8551",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31525\" xsd:anyURI"
] | null | null | false | true | 2 |
GO:0006546 | 6,546 | glycine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of glycine. | [
"GOC:curators"
] | null | [
"glycine breakdown",
"glycine catabolism",
"glycine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:PWY0-1608",
"Reactome:R-HSA-6783984 \"Glycine degradation\""
] | [
"GO:0006544",
"GO:0170040",
"GO:1901606"
] | [] | [] | [] | [
"GO:0006544",
"GO:0170040",
"GO:1901606"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PWY0-1608",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31405\" xsd:anyURI"
] | null | null | false | true | 1 |
GO:0006547 | 6,547 | obsolete L-histidine metabolic process | biological_process | OBSOLETE. The chemical reactions and pathways involving L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. | [
"GOC:curators"
] | This term was obsoleted because it is an unnecessary grouping term. | [
"histidine metabolic process",
"histidine metabolism"
] | [
"BROAD",
"EXACT"
] | [] | [] | [
"Wikipedia:Histidine"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0000105",
"GO:0006548"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31172\" xsd:anyURI"
] | null | null | true | true | 3 |
GO:0006548 | 6,548 | L-histidine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-histidine. | [
"GOC:curators"
] | null | [
"histidine breakdown",
"histidine catabolic process",
"histidine catabolism",
"histidine degradation"
] | [
"EXACT",
"BROAD",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:HISDEG-PWY",
"MetaCyc:HISHP-PWY",
"MetaCyc:HISTDEG-PWY",
"MetaCyc:PWY-5028",
"MetaCyc:PWY-5030",
"MetaCyc:PWY-5031",
"Reactome:R-HSA-70921 \"Histidine catabolism\""
] | [
"GO:0009074",
"GO:0052805",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0009074",
"GO:0052805",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:HISDEG-PWY",
"skos:narrowMatch MetaCyc:HISHP-PWY",
"skos:narrowMatch MetaCyc:HISTDEG-PWY",
"skos:narrowMatch MetaCyc:PWY-5028",
"skos:narrowMatch MetaCyc:PWY-5030",
"skos:narrowMatch MetaCyc:PWY-5031",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/3020... | null | null | false | true | 2 |
GO:0006549 | 6,549 | isoleucine metabolic process | biological_process | The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. | [
"GOC:ai"
] | null | [
"isoleucine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0009081",
"GO:1901605"
] | [] | [] | [] | [
"GO:0009081",
"GO:1901605"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006550 | 6,550 | L-isoleucine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-isoleucine. | [
"GOC:curators"
] | null | [
"isoleucine breakdown",
"isoleucine catabolism",
"isoleucine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:ILEUDEG-PWY",
"MetaCyc:PWY-5078",
"MetaCyx:PWY-8184"
] | [
"GO:0006549",
"GO:0009083",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006549",
"GO:0009083",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:ILEUDEG-PWY",
"skos:narrowMatch MetaCyc:PWY-5078",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30047\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31405\" xsd:anyURI"
] | null | null | false | true | 4 |
GO:0006551 | 6,551 | L-leucine metabolic process | biological_process | The chemical reactions and pathways involving L-leucine, 2-amino-4-methylpentanoic acid. | [
"GOC:ai"
] | null | [
"L-leucine metabolism",
"leucine metabolic process"
] | [
"EXACT",
"BROAD"
] | [] | [] | [] | [
"GO:0009081",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0009081",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0006552 | 6,552 | L-leucine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-leucine. | [
"GOC:curators"
] | null | [
"L-leucine breakdown",
"L-leucine catabolism",
"L-leucine degradation",
"leucine catabolic process"
] | [
"EXACT",
"EXACT",
"EXACT",
"BROAD"
] | [] | [] | [
"MetaCyc:LEU-DEG2-PWY",
"MetaCyc:PWY-5075",
"MetaCyc:PWY-5076",
"MetaCyc:PWY-7767",
"MetaCyc:PWY-8185"
] | [
"GO:0006551",
"GO:0009083",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006551",
"GO:0009083",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:LEU-DEG2-PWY",
"skos:narrowMatch MetaCyc:PWY-5075",
"skos:narrowMatch MetaCyc:PWY-5076",
"skos:narrowMatch MetaCyc:PWY-7767",
"skos:narrowMatch MetaCyc:PWY-8185",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30047\" xsd:anyURI",
"term_tracker_item \"h... | null | null | false | true | 9 |
GO:0006553 | 6,553 | obsolete lysine metabolic process | biological_process | OBSOLETE. The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. | [
"GOC:curators"
] | This term was obsoleted because it is an unnecessary grouping term. | [
"lysine metabolism"
] | [
"EXACT"
] | [] | [] | [
"Wikipedia:Lysine"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0009085",
"GO:0019477"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31172\" xsd:anyURI"
] | null | null | true | true | 7 |
GO:0006554 | 6,554 | obsolete lysine catabolic process | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid. | [
"GOC:curators"
] | The reason for obsoletion is that more specific terms were created. | [
"lysine breakdown",
"lysine catabolism",
"lysine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-71064 \"Lysine catabolism\""
] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0019477"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31068\" xsd:anyURI"
] | null | null | true | true | 8 |
GO:0006555 | 6,555 | L-methionine metabolic process | biological_process | The chemical reactions and pathways involving L-methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. | [
"GOC:jl",
"ISBN:0198506732"
] | null | [
"methionine and threonine metabolic process",
"methionine and threonine metabolism",
"methionine metabolism"
] | [
"BROAD",
"BROAD",
"EXACT"
] | [] | [] | [
"UM-BBD_pathwayID:met"
] | [
"GO:0000096",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0000096",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31318\" xsd:anyURI"
] | null | null | false | true | 9 |
GO:0006556 | 6,556 | S-adenosylmethionine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. | [
"GOC:curators",
"ISBN:0198506732"
] | null | [
"S-adenosyl methionine biosynthesis",
"S-adenosyl methionine biosynthetic process",
"S-adenosylmethionine anabolism",
"S-adenosylmethionine biosynthesis",
"S-adenosylmethionine formation",
"S-adenosylmethionine synthesis",
"SAM biosynthetic process"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:SAM-PWY"
] | [
"GO:0044272",
"GO:0046500"
] | [] | [] | [] | [
"GO:0044272",
"GO:0046500"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006557 | 6,557 | obsolete S-adenosylmethioninamine biosynthetic process | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt. | [
"GOC:mah",
"MetaCyc:S-ADENOSYLMETHIONINAMINE"
] | This term was obsoleted because it represents a molecular function. | [
"S-adenosylmethioninamine anabolism",
"S-adenosylmethioninamine biosynthesis",
"S-adenosylmethioninamine formation",
"S-adenosylmethioninamine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [
"GO:0006745"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0004014"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23295\" xsd:anyURI"
] | null | null | true | true | 8 |
GO:0006558 | 6,558 | L-phenylalanine metabolic process | biological_process | The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid. | [
"GOC:jsg",
"GOC:mah"
] | null | [
"L-phenylalanine metabolism",
"phenylalanine metabolic process",
"phenylalanine metabolism"
] | [
"EXACT",
"BROAD",
"BROAD"
] | [] | [] | [
"Reactome:R-HSA-8964208 \"Phenylalanine metabolism\""
] | [
"GO:0009072",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0009072",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0006559 | 6,559 | L-phenylalanine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-phenylalanine. | [
"GOC:curators"
] | null | [
"L-phenylalanine breakdown",
"L-phenylalanine catabolism",
"L-phenylalanine degradation",
"phenylalanine catabolic process",
"phenylalanine catabolism"
] | [
"EXACT",
"EXACT",
"EXACT",
"BROAD",
"BROAD"
] | [] | [] | [
"MetaCyc:ANAPHENOXI-PWY",
"MetaCyc:PWY-5079",
"MetaCyc:PWY-6318",
"MetaCyc:PWY-7158",
"MetaCyc:PWY-8014"
] | [
"GO:0006558",
"GO:0009074",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006558",
"GO:0009074",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:ANAPHENOXI-PWY",
"skos:narrowMatch MetaCyc:PWY-5079",
"skos:narrowMatch MetaCyc:PWY-6318",
"skos:narrowMatch MetaCyc:PWY-7158",
"skos:narrowMatch MetaCyc:PWY-8014",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tracker_item \... | null | null | false | true | 2 |
GO:0006560 | 6,560 | L-proline metabolic process | biological_process | The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. | [
"GOC:jl",
"ISBN:0198506732"
] | null | [
"proline metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006562 | 6,562 | L-proline catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-proline. | [
"GOC:curators"
] | null | [
"proline breakdown",
"proline catabolism",
"proline degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:PROUT-PWY",
"MetaCyc:PWY-8186",
"Reactome:R-HSA-70688 \"Proline catabolism\""
] | [
"GO:0006560",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006560",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PROUT-PWY",
"skos:narrowMatch MetaCyc:PWY-8186",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31405\" xsd:anyURI"
] | null | null | false | true | 5 |
GO:0006563 | 6,563 | L-serine metabolic process | biological_process | The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. | [
"GOC:ai",
"GOC:jsg"
] | null | [
"L-serine metabolism"
] | [
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-977347 \"Serine metabolism\""
] | [
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0006565 | 6,565 | L-serine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-serine. | [
"GOC:curators"
] | null | [
"L-serine breakdown",
"L-serine catabolism",
"L-serine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:SERDEG-PWY"
] | [
"GO:0006563",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006563",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch MetaCyc:SERDEG-PWY",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30758\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31405\" xsd:anyURI"
] | null | null | false | true | 2 |
GO:0006566 | 6,566 | L-threonine metabolic process | biological_process | The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. | [
"GOC:jl",
"ISBN:0198506732"
] | null | [
"methionine and threonine metabolic process",
"methionine and threonine metabolism",
"threonine metabolism"
] | [
"BROAD",
"BROAD",
"EXACT"
] | [] | [] | [
"UM-BBD_pathwayID:met"
] | [
"GO:0019752"
] | [] | [] | [] | [
"GO:0019752"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0006567 | 6,567 | L-threonine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-threonine. | [
"GOC:curators"
] | null | [
"threonine breakdown",
"threonine catabolism",
"threonine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:PWY-5436",
"MetaCyc:PWY-5437",
"MetaCyc:PWY66-428",
"MetaCyc:THRDLCTCAT-PWY",
"MetaCyc:THREONINE-DEG2-PWY",
"UM-BBD_pathwayID:met"
] | [
"GO:0006566",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006566",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PWY-5436",
"skos:narrowMatch MetaCyc:PWY-5437",
"skos:narrowMatch MetaCyc:PWY66-428",
"skos:narrowMatch MetaCyc:THRDLCTCAT-PWY",
"skos:narrowMatch MetaCyc:THREONINE-DEG2-PWY",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tra... | null | null | false | true | 9 |
GO:0006568 | 6,568 | L-tryptophan metabolic process | biological_process | The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. | [
"ISBN:0198547684"
] | null | [
"tryptophan metabolic process",
"tryptophan metabolism"
] | [
"RELATED",
"RELATED"
] | [] | [] | [
"Wikipedia:Tryptophan"
] | [
"GO:0009072",
"GO:0042430",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0009072",
"GO:0042430",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0006569 | 6,569 | L-tryptophan catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-tryptophan. | [
"GOC:curators"
] | null | [
"tryptophan breakdown",
"tryptophan catabolic process",
"tryptophan catabolic process, using tryptophanase",
"tryptophan catabolism",
"tryptophan catabolism, using tryptophanase",
"tryptophan degradation"
] | [
"EXACT",
"RELATED",
"NARROW",
"EXACT",
"NARROW",
"EXACT"
] | [] | [] | [
"MetaCyc:PWY-3162",
"MetaCyc:PWY-3181",
"MetaCyc:PWY-5081",
"MetaCyc:PWY-5651",
"MetaCyc:PWY-5655",
"MetaCyc:PWY-6307",
"MetaCyc:PWY-6309",
"MetaCyc:PWY-6505",
"MetaCyc:PWY-8017",
"MetaCyc:TRPCAT-PWY",
"MetaCyc:TRPKYNCAT-PWY",
"MetaCyc:TRYPDEG-PWY",
"MetaCyc:TRYPTOPHAN-DEGRADATION-1",
"Rea... | [
"GO:0006568",
"GO:0009074",
"GO:0042436",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006568",
"GO:0009074",
"GO:0042436",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PWY-3162",
"skos:narrowMatch MetaCyc:PWY-3181",
"skos:narrowMatch MetaCyc:PWY-5081",
"skos:narrowMatch MetaCyc:PWY-5651",
"skos:narrowMatch MetaCyc:PWY-5655",
"skos:narrowMatch MetaCyc:PWY-6307",
"skos:narrowMatch MetaCyc:PWY-6309",
"skos:narrowMatch MetaCyc:PWY-6505",
"sko... | null | null | false | true | 5 |
GO:0006570 | 6,570 | tyrosine metabolic process | biological_process | The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. | [
"GOC:curators"
] | null | [
"tyrosine metabolism"
] | [
"EXACT"
] | [] | [] | [
"UM-BBD_pathwayID:tyr",
"Wikipedia:Tyrosine"
] | [
"GO:0009072",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [
"GO:0009072",
"GO:0170033",
"GO:0170039"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006571 | 6,571 | L-tyrosine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. | [
"GOC:sm"
] | null | [
"tyrosine anabolism",
"tyrosine biosynthesis",
"tyrosine formation",
"tyrosine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [
"GO:0019291"
] | [] | [
"MetaCyc:PWY-3461",
"MetaCyc:PWY-6120",
"MetaCyc:PWY-6134",
"MetaCyc:TYRSYN"
] | [
"GO:0006570",
"GO:0009073",
"GO:1902223"
] | [] | [] | [] | [
"GO:0006570",
"GO:0009073",
"GO:1902223"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PWY-3461",
"skos:narrowMatch MetaCyc:PWY-6120",
"skos:narrowMatch MetaCyc:PWY-6134",
"skos:narrowMatch MetaCyc:TYRSYN",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20583\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/is... | null | null | false | true | 6 |
GO:0006572 | 6,572 | L-tyrosine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-tyrosine. | [
"GOC:curators"
] | null | [
"tyrosine breakdown",
"tyrosine catabolism",
"tyrosine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:PWY-5151",
"MetaCyc:PWY-7514",
"MetaCyc:PWY-8016",
"MetaCyc:PWY3O-4108",
"MetaCyc:TYRFUMCAT-PWY",
"Reactome:R-HSA-8963684 \"Tyrosine catabolism\""
] | [
"GO:0006570",
"GO:0009074",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006570",
"GO:0009074",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PWY-5151",
"skos:narrowMatch MetaCyc:PWY-7514",
"skos:narrowMatch MetaCyc:PWY-8016",
"skos:narrowMatch MetaCyc:PWY3O-4108",
"skos:narrowMatch MetaCyc:TYRFUMCAT-PWY",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tracker_item ... | null | null | false | true | 3 |
GO:0006573 | 6,573 | valine metabolic process | biological_process | The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid. | [
"GOC:ai"
] | null | [
"valine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0009081",
"GO:1901605"
] | [] | [] | [] | [
"GO:0009081",
"GO:1901605"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006574 | 6,574 | L-valine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-valine. | [
"GOC:curators"
] | null | [
"valine breakdown",
"valine catabolism",
"valine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [
"GO:1990292"
] | [] | [
"MetaCyc:PWY-5057",
"MetaCyc:PWY-8183",
"MetaCyc:VALDEG-PWY"
] | [
"GO:0006573",
"GO:0009083",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [
"GO:0006573",
"GO:0009083",
"GO:0170035",
"GO:0170040"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:PWY-5057",
"skos:narrowMatch MetaCyc:PWY-8183",
"skos:narrowMatch MetaCyc:VALDEG-PWY",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30047\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31221\" xsd:anyURI",
"term_t... | null | null | false | true | 4 |
GO:0006575 | 6,575 | modified amino acid metabolic process | biological_process | The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. | [
"GOC:ai"
] | null | [
"amino acid derivative metabolic process",
"cellular amino acid derivative metabolic process",
"cellular amino acid derivative metabolism",
"cellular modified amino acid metabolic process",
"cellular modified amino acid metabolism",
"modified amino acid metabolism"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [
"goslim_drosophila",
"goslim_generic",
"goslim_prokaryote"
] | [] | [
"GO:0008152"
] | [] | [] | [] | [
"GO:0008152"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28908\" xsd:anyURI"
] | null | null | false | true | 4 |
GO:0006576 | 6,576 | biogenic amine metabolic process | biological_process | The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. | [
"GOC:jl",
"ISBN:0395825172"
] | null | [
"biogenic amine metabolism",
"cellular biogenic amine metabolic process"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0009308"
] | [] | [] | [] | [
"GO:0009308"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006577 | 6,577 | amino-acid betaine metabolic process | biological_process | The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid. | [
"GOC:mah",
"ISBN:0198506732"
] | null | [
"betaine metabolic process",
"betaine metabolism"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006575"
] | [] | [] | [] | [
"GO:0006575"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0006579 | 6,579 | amino-acid betaine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid. | [
"GOC:mah",
"ISBN:0198506732"
] | null | [
"betaine breakdown",
"betaine catabolic process",
"betaine catabolism",
"betaine degradation"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006577",
"GO:0042219"
] | [] | [] | [] | [
"GO:0006577",
"GO:0042219"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0006580 | 6,580 | ethanolamine metabolic process | biological_process | The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine). | [
"ISBN:0192800981"
] | null | [
"ethanolamine metabolism"
] | [
"EXACT"
] | [
"GO:0006645"
] | [] | [] | [
"GO:0009308",
"GO:0034308"
] | [] | [] | [] | [
"GO:0009308",
"GO:0034308"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0006581 | 6,581 | acetylcholine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline. | [
"GOC:jl",
"ISBN:0192800752"
] | null | [
"acetylcholine breakdown",
"acetylcholine catabolism",
"acetylcholine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0008291",
"GO:0009056"
] | [] | [] | [] | [
"GO:0008291",
"GO:0009056"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0006582 | 6,582 | melanin metabolic process | biological_process | The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. | [
"GOC:curators"
] | null | [
"melanin metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0018958",
"GO:0019748",
"GO:0042440"
] | [] | [] | [] | [
"GO:0018958",
"GO:0019748",
"GO:0042440"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0006583 | 6,583 | melanin biosynthetic process from tyrosine | biological_process | The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine. | [
"GOC:curators"
] | null | [
"melanin anabolism from tyrosine",
"melanin formation from tyrosine",
"melanin synthesis from tyrosine"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006570",
"GO:0042438"
] | [] | [] | [] | [
"GO:0006570",
"GO:0042438"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0006584 | 6,584 | catecholamine metabolic process | biological_process | The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. | [
"GOC:jl",
"ISBN:0198506732"
] | null | [
"catecholamine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0006576",
"GO:0009712"
] | [] | [] | [] | [
"GO:0006576",
"GO:0009712"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0006585 | 6,585 | dopamine biosynthetic process from tyrosine | biological_process | The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine. | [
"GOC:bf",
"GOC:jl",
"ISBN:0198506732"
] | null | [
"dopamine anabolism from tyrosine",
"dopamine formation from tyrosine",
"dopamine synthesis from tyrosine"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006570",
"GO:0042416"
] | [] | [] | [] | [
"GO:0006570",
"GO:0042416"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0006586 | 6,586 | obsolete indolalkylamine metabolic process | biological_process | OBSOLETE. The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. | [
"GOC:curators"
] | This term was obsoleted because it is an unnecessary grouping class. | [
"indolalkylamine metabolism",
"indolamine metabolic process",
"indolamine metabolism"
] | [
"EXACT",
"BROAD",
"BROAD"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI"
] | null | null | true | true | 4 |
GO:0006587 | 6,587 | serotonin biosynthetic process from L-tryptophan | biological_process | The chemical reactions and pathways resulting in the formation from L-tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. | [
"GOC:jl",
"ISBN:0198506732",
"PMID:30901029",
"PMID:35495641"
] | null | [
"serotonin anabolism from tryptophan",
"serotonin formation from tryptophan",
"serotonin synthesis from tryptophan"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006568",
"GO:0042427"
] | [] | [] | [] | [
"GO:0006568",
"GO:0042427"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31021\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31587\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31658\" xsd:anyURI"
] | null | null | false | true | 9 |
GO:0006588 | 6,588 | obsolete activation of tryptophan 5-monooxygenase activity | biological_process | OBSOLETE. The process in which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity. | [
"GOC:dph",
"GOC:tb"
] | This term was obsoleted because it represents a molecular function. | [
"tryptophan hydroxylase activation"
] | [
"RELATED"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI"
] | null | null | true | true | 9 |
GO:0006589 | 6,589 | octopamine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species. | [
"ISBN:0198506732"
] | null | [
"octopamine anabolism",
"octopamine biosynthesis",
"octopamine formation",
"octopamine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0042401",
"GO:0046165",
"GO:0046189",
"GO:0046333"
] | [] | [] | [] | [
"GO:0042401",
"GO:0046165",
"GO:0046189",
"GO:0046333"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0006590 | 6,590 | thyroid hormone generation | biological_process | The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. | [
"GOC:jl",
"ISBN:0716720094"
] | Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because thyroid hormones can only be formed by the proteolysis of a larger molecule (see term definition). The word 'generation' is therefore us... | [] | [] | [] | [] | [
"Reactome:R-HSA-209968 \"Thyroxine biosynthesis\""
] | [
"GO:0042403"
] | [] | [] | [] | [
"GO:0042403"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0006591 | 6,591 | ornithine metabolic process | biological_process | The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. | [
"GOC:jl",
"ISBN:0192801023"
] | null | [
"ornithine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0170041",
"GO:1901605"
] | [] | [] | [] | [
"GO:0170041",
"GO:1901605"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0006592 | 6,592 | ornithine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. | [
"GOC:jl",
"ISBN:0192801023"
] | null | [
"ornithine anabolism",
"ornithine biosynthesis",
"ornithine formation",
"ornithine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:ARGININE-SYN4-PWY",
"MetaCyc:GLUTORN-PWY",
"MetaCyc:PWY-6922"
] | [
"GO:0006591",
"GO:0170043",
"GO:1901607"
] | [] | [] | [] | [
"GO:0006591",
"GO:0170043",
"GO:1901607"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:ARGININE-SYN4-PWY",
"skos:narrowMatch MetaCyc:GLUTORN-PWY",
"skos:narrowMatch MetaCyc:PWY-6922",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28527\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31510\" xsd:anyURI"
... | null | null | false | true | 8 |
GO:0006593 | 6,593 | L-ornithine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of L-ornithine. | [
"GOC:curators"
] | null | [
"ornithine breakdown",
"ornithine catabolism",
"ornithine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006591",
"GO:0170035",
"GO:0170044"
] | [] | [] | [] | [
"GO:0006591",
"GO:0170035",
"GO:0170044"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31405\" xsd:anyURI"
] | null | null | false | true | 2 |
GO:0006595 | 6,595 | polyamine metabolic process | biological_process | The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups. | [
"ISBN:0198506732"
] | null | [
"polyamine metabolism"
] | [
"EXACT"
] | [] | [
"goslim_drosophila",
"goslim_pombe"
] | [
"Reactome:R-HSA-351202 \"Metabolism of polyamines\""
] | [
"GO:0006576"
] | [] | [] | [] | [
"GO:0006576"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0006596 | 6,596 | polyamine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. | [
"ISBN:0198506732"
] | null | [
"polyamine anabolism",
"polyamine biosynthesis",
"polyamine formation",
"polyamine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:POLYAMINSYN3-PWY",
"MetaCyc:POLYAMSYN-PWY",
"Reactome:R-HSA-351200 \"Interconversion of polyamines\""
] | [
"GO:0006595",
"GO:0042401"
] | [] | [] | [] | [
"GO:0006595",
"GO:0042401"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch MetaCyc:POLYAMINSYN3-PWY",
"skos:narrowMatch MetaCyc:POLYAMSYN-PWY",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28527\" xsd:anyURI"
] | null | null | false | true | 2 |
GO:0006597 | 6,597 | spermine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging. | [
"GOC:curators",
"MetaCyc:ARGSPECAT-PWY"
] | null | [
"spermine anabolism",
"spermine biosynthesis",
"spermine formation",
"spermine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:ARGSPECAT-PWY"
] | [
"GO:0006596",
"GO:0008215"
] | [] | [] | [] | [
"GO:0006596",
"GO:0008215"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006599 | 6,599 | obsolete phosphagen metabolic process | biological_process | OBSOLETE. The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. | [
"GOC:jl",
"ISBN:0198506732"
] | This term was obsoleted because it is an unnecessary grouping class. | [
"phosphagen metabolism"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI"
] | null | null | true | true | 7 |
GO:0006600 | 6,600 | creatine metabolic process | biological_process | The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle. | [
"GOC:jl",
"ISBN:0192801023"
] | null | [
"creatine metabolism"
] | [
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-71288 \"Creatine metabolism\""
] | [
"GO:0006575",
"GO:0032787"
] | [] | [] | [] | [
"GO:0006575",
"GO:0032787"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0006601 | 6,601 | creatine biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetat... | [
"GOC:mah",
"MetaCyc:GLYCGREAT-PWY"
] | null | [
"creatine anabolism",
"creatine biosynthesis",
"creatine formation",
"creatine synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"MetaCyc:GLYCGREAT-PWY"
] | [
"GO:0006600",
"GO:0042398",
"GO:0072330"
] | [] | [] | [] | [
"GO:0006600",
"GO:0042398",
"GO:0072330"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28523\" xsd:anyURI"
] | null | null | false | true | 3 |
GO:0006602 | 6,602 | creatinine catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine. | [
"ISBN:0198506732"
] | null | [
"creatinine breakdown",
"creatinine catabolism",
"creatinine degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0046449",
"GO:0072340"
] | [] | [] | [] | [
"GO:0046449",
"GO:0072340"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0006603 | 6,603 | phosphocreatine metabolic process | biological_process | The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle. | [
"PMID:16371597"
] | null | [
"phosphocreatine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0006575",
"GO:0006796",
"GO:0019637"
] | [] | [] | [] | [
"GO:0006575",
"GO:0006796",
"GO:0019637"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0006604 | 6,604 | obsolete phosphoarginine metabolic process | biological_process | OBSOLETE. The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates. | [
"GOC:curators",
"PMID:16371597"
] | This term was obsoleted because it is an unnecessary grouping class. | [
"phosphoarginine metabolism"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI"
] | null | null | true | true | 1 |
GO:0006605 | 6,605 | protein targeting | biological_process | The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. | [
"GOC:ma"
] | null | [
"nascent polypeptide association",
"protein sorting along secretory pathway"
] | [
"RELATED",
"NARROW"
] | [] | [
"goslim_chembl",
"goslim_pombe",
"goslim_yeast"
] | [
"Wikipedia:Protein_targeting"
] | [
"GO:0045184"
] | [] | [] | [] | [
"GO:0045184"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26248\" xsd:anyURI"
] | null | null | false | true | 9 |
GO:0006606 | 6,606 | protein import into nucleus | biological_process | The directed movement of a protein from the cytoplasm to the nucleus. | [
"GOC:jl"
] | null | [
"establishment of protein localization to nucleus",
"protein import into cell nucleus",
"protein nucleus import",
"protein transport from cytoplasm to nucleus"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006886",
"GO:0034504",
"GO:0051170",
"GO:0072594"
] | [] | [] | [] | [
"GO:0006886",
"GO:0034504",
"GO:0051170",
"GO:0072594"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0006607 | 6,607 | NLS-bearing protein import into nucleus | biological_process | The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope. | [
"GOC:ai"
] | null | [
"NLS-bearing substrate import into cell nucleus",
"NLS-bearing substrate import into nucleus",
"NLS-bearing substrate transport from cytoplasm to nucleus",
"NLS-bearing substrate-nucleus import"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006606"
] | [] | [] | [] | [
"GO:0006606"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0006608 | 6,608 | obsolete snRNP protein import into nucleus | biological_process | OBSOLETE. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane. | [
"GOC:ai"
] | The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. | [
"snRNP protein import into cell nucleus",
"snRNP protein transport from cytoplasm to nucleus",
"snRNP protein-nucleus import"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0006606"
] | [] | null | null | true | true | 3 |
GO:0006609 | 6,609 | obsolete mRNA-binding (hnRNP) protein import into nucleus | biological_process | OBSOLETE. The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane. | [
"GOC:mah"
] | The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models. | [
"mRNA-binding (hnRNP) protein import into cell nucleus",
"mRNA-binding (hnRNP) protein transport from cytoplasm to nucleus",
"mRNA-binding (hnRNP) protein-nucleus import"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0006606"
] | [] | null | null | true | true | 2 |
GO:0006610 | 6,610 | ribosomal protein import into nucleus | biological_process | The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus. | [
"GOC:ai",
"PMID:11809816"
] | Ribosomal protein rpl12 uses a different import pathway, which is why it has a separate GO term. | [
"ribosomal protein import into cell nucleus",
"ribosomal protein transport from cytoplasm to nucleus",
"ribosomal protein-nucleus import"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006606"
] | [] | [] | [] | [
"GO:0006606"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13686\" xsd:anyURI"
] | null | null | false | true | 1 |
GO:0006611 | 6,611 | protein export from nucleus | biological_process | The directed movement of a protein from the nucleus into the cytoplasm. | [
"GOC:jl"
] | null | [
"copper-induced protein export from nucleus",
"protein export from cell nucleus",
"protein export out of nucleus",
"protein transport from nucleus to cytoplasm",
"protein-nucleus export"
] | [
"RELATED",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [
"GO:0097349"
] | [] | [] | [
"GO:0006886",
"GO:0051168"
] | [] | [] | [] | [
"GO:0006886",
"GO:0051168"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0006612 | 6,612 | protein targeting to membrane | biological_process | The process of directing proteins towards a membrane, usually using signals contained within the protein. | [
"GOC:curators"
] | null | [
"protein membrane targeting",
"protein-membrane targeting"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006605",
"GO:0090150"
] | [] | [] | [] | [
"GO:0006605",
"GO:0090150"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
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