go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0006613
6,613
cotranslational protein targeting to membrane
biological_process
The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.
[ "ISBN:0716731363", "PMID:10512867", "PMID:16896215" ]
null
[ "cotranslational membrane targeting", "cotranslational protein membrane targeting", "cotranslational protein-membrane targeting" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006612" ]
[]
[]
[]
[ "GO:0006612" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006614
6,614
SRP-dependent cotranslational protein targeting to membrane
biological_process
The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal u...
[ "ISBN:0716731363" ]
null
[ "ER translocation", "SRP-dependent cotranslational membrane targeting", "SRP-dependent cotranslational protein-membrane targeting" ]
[ "BROAD", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1799339 \"SRP-dependent cotranslational protein targeting to membrane\"" ]
[ "GO:0006613", "GO:0045047" ]
[ "has_part GO:0006412" ]
[ "has_part" ]
[ "GO:0006412" ]
[ "GO:0006412", "GO:0006613", "GO:0045047" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0006615
6,615
SRP-dependent cotranslational protein targeting to membrane, docking
biological_process
The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting.
[ "ISBN:0815316194" ]
null
[ "protein docking during SRP-dependent cotranslational protein targeting to membrane", "SRP-dependent cotranslational membrane targeting, docking", "SRP-dependent cotranslational protein-membrane targeting, docking" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0022615" ]
[ "part_of GO:0006614" ]
[ "part_of" ]
[ "GO:0006614" ]
[ "GO:0006614", "GO:0022615" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006616
6,616
SRP-dependent cotranslational protein targeting to membrane, translocation
biological_process
The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called...
[ "ISBN:0716731363" ]
null
[ "ER translocation", "SRP-dependent cotranslational membrane targeting, translocation", "SRP-dependent cotranslational protein-membrane targeting, translocation", "translocation during SRP-dependent cotranslational protein targeting to membrane" ]
[ "BROAD", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0065002" ]
[ "part_of GO:0006614" ]
[ "part_of" ]
[ "GO:0006614" ]
[ "GO:0006614", "GO:0065002" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0006617
6,617
SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
biological_process
The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.
[ "ISBN:0815316194" ]
null
[ "signal sequence recognition during SRP-dependent cotranslational protein targeting to membrane", "SRP-dependent cotranslational membrane targeting, signal sequence recognition", "SRP-dependent cotranslational protein-membrane targeting, signal sequence recognition" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0065003" ]
[ "part_of GO:0006614" ]
[ "part_of" ]
[ "GO:0006614" ]
[ "GO:0006614", "GO:0065003" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006618
6,618
obsolete SRP-dependent cotranslational protein targeting to membrane, signal sequence processing
biological_process
OBSOLETE. The removal of the signal peptide from a nascent protein during cotranslational membrane targeting.
[ "ISBN:0815316194" ]
This term was obsoleted because it reprenset a molecular function, signal peptidase activity ; GO:0009003.
[ "signal sequence processing during SRP-dependent cotranslational protein targeting to membrane", "SRP-dependent cotranslational membrane targeting, signal sequence processing", "SRP-dependent cotranslational protein-membrane targeting, signal sequence processing" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0051604" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30479\" xsd:anyURI" ]
null
null
true
true
6
GO:0006619
6,619
obsolete SRP-independent cotranslational protein-membrane targeting
biological_process
OBSOLETE. The targeting of proteins to a membrane that occurs during translation and is independent of SRP and signal recognition.
[ "GOC:ai", "PMID:11101515" ]
This term was made obsolete because there is no evidence for the existence of this process.
[ "ER translocation", "SRP-independent cotranslational membrane targeting", "SRP-independent cotranslational protein-membrane targeting" ]
[ "BROAD", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
8
GO:0006620
6,620
post-translational protein targeting to endoplasmic reticulum membrane
biological_process
The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones wh...
[ "ISBN:0716731363" ]
null
[ "posttranslational endoplasmic reticulum membrane targeting", "posttranslational endoplasmic reticulum protein-membrane targeting", "posttranslational protein endoplasmic reticulum membrane targeting", "posttranslational protein targeting to endoplasmic reticulum membrane", "posttranslational protein target...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006612", "GO:0045047" ]
[]
[]
[]
[ "GO:0006612", "GO:0045047" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006621
6,621
protein retention in ER lumen
biological_process
The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unasse...
[ "ISBN:0716731363", "PMID:12972550" ]
null
[ "maintenance of protein location in ER lumen" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0035437" ]
[]
[]
[]
[ "GO:0035437" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006622
6,622
protein targeting to lysosome
biological_process
The process of directing proteins towards the lysosome using signals contained within the protein.
[ "GOC:curators" ]
null
[ "protein-lysosome targeting" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006623", "GO:0007041", "GO:0061462" ]
[]
[]
[]
[ "GO:0006623", "GO:0007041", "GO:0061462" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006623
6,623
protein targeting to vacuole
biological_process
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
[ "GOC:curators" ]
null
[ "protein vacuolar targeting", "protein-vacuolar targeting", "protein-vacuole targeting", "vacuolar protein sorting" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006605", "GO:0006886", "GO:0007034", "GO:0072665", "GO:0072666" ]
[]
[]
[]
[ "GO:0006605", "GO:0006886", "GO:0007034", "GO:0072665", "GO:0072666" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006624
6,624
vacuolar protein processing
biological_process
Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.
[ "GOC:mah" ]
null
[ "vacuolar protein maturation", "vacuolar proteolysis" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0016485" ]
[ "occurs_in GO:0005773" ]
[ "occurs_in" ]
[ "GO:0005773" ]
[ "GO:0005773", "GO:0016485" ]
[ "GO:0016485", "occurs_in GO:0005773" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0006625
6,625
protein targeting to peroxisome
biological_process
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
[ "GOC:ai" ]
null
[ "protein-peroxisome targeting" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006605", "GO:0072663" ]
[]
[]
[]
[ "GO:0006605", "GO:0072663" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006626
6,626
obsolete protein targeting to mitochondrion
biological_process
OBSOLETE. The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
[ "GOC:mcc", "ISBN:0716731363" ]
The reason for obsoletion is that this term was added in error.
[ "mitochondrial protein import", "mitochondrial translocation", "protein import into mitochondrion", "protein targeting to mitochondria", "protein-mitochondrial targeting" ]
[ "RELATED", "RELATED", "EXACT", "EXACT", "EXACT" ]
[ "GO:0043681" ]
[]
[ "Reactome:R-HSA-1268020 \"Mitochondrial protein import\"" ]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0070585" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30349\" xsd:anyURI" ]
dragon-ai-agent
null
true
true
6
GO:0006627
6,627
obsolete protein processing involved in protein targeting to mitochondrion
biological_process
OBSOLETE. The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
[ "GOC:mcc", "PMID:12191769" ]
The reason for obsoletion is that this term was added in error.
[ "mitochondrial processing", "mitochondrial protein processing during import" ]
[ "BROAD", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0070585" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30349\" xsd:anyURI" ]
dragon-ai-agent
null
true
true
6
GO:0006628
6,628
obsolete mitochondrial translocation
biological_process
OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import machinery (MOM complex) and the inner membrane import machinery (MIM complex) form translocation contact sites as a part of the membrane preprotein import machinery.
[ "PMID:7600576" ]
This term was made obsolete because its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import ; GO:0030150' while the mitochondrial translocation has a broader meaning; this led to mis-annotation.
[ "mitochondrial translocation" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0070585" ]
[]
null
null
true
true
1
GO:0006629
6,629
lipid metabolic process
biological_process
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and...
[ "GOC:ma" ]
null
[ "lipid metabolism" ]
[ "EXACT" ]
[]
[ "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_euk_cellular_processes_ribbon", "goslim_generic", "goslim_metagenomics", "goslim_mouse", "goslim_pir", "goslim_plant", "goslim_plant_ribbon", "goslim_pombe", "goslim_prokaryote", "goslim_prokaryote_ribbon", "go...
[ "Reactome:R-HSA-556833 \"Metabolism of lipids\"", "Wikipedia:Lipid_metabolism" ]
[ "GO:0044238" ]
[]
[]
[]
[ "GO:0044238" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006630
6,630
obsolete lipid binding
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:curators" ]
This term was made obsolete because it represents a molecular function and not a biological process.
[ "lipid binding" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0008289" ]
[]
null
null
true
true
9
GO:0006631
6,631
fatty acid metabolic process
biological_process
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
[ "ISBN:0198547684" ]
null
[ "fatty acid metabolism" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-211935 \"Fatty acids\"", "Reactome:R-HSA-434313 \"Intracellular metabolism of fatty acids regulates insulin secretion\"", "Reactome:R-HSA-8978868 \"Fatty acid metabolism\"", "Wikipedia:Fatty_acid_metabolism" ]
[ "GO:0006629", "GO:0032787" ]
[]
[]
[]
[ "GO:0006629", "GO:0032787" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28908\" xsd:anyURI" ]
null
null
false
true
2
GO:0006633
6,633
fatty acid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branche...
[ "GOC:mah", "ISBN:0198506732" ]
null
[ "fatty acid anabolism", "fatty acid biosynthesis", "fatty acid formation", "fatty acid synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0000037" ]
[]
[ "MetaCyc:FASYN-INITIAL-PWY", "MetaCyc:PWY-4381", "MetaCyc:PWY-5156", "Wikipedia:Fatty_acid_synthesis" ]
[ "GO:0006631", "GO:0008610", "GO:0072330" ]
[]
[]
[]
[ "GO:0006631", "GO:0008610", "GO:0072330" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch MetaCyc:FASYN-INITIAL-PWY", "skos:narrowMatch MetaCyc:PWY-4381", "skos:narrowMatch MetaCyc:PWY-5156", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28527\" xsd:anyURI" ]
null
null
false
true
4
GO:0006634
6,634
hexadecanal biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde.
[ "https://en.wikipedia.org/wiki/Hexadecanal" ]
null
[ "hexadecanal anabolism", "hexadecanal biosynthesis", "hexadecanal formation", "hexadecanal synthesis", "palmitaldehyde biosynthesis", "palmitaldehyde biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046184", "GO:0046458" ]
[]
[]
[]
[ "GO:0046184", "GO:0046458" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006635
6,635
fatty acid beta-oxidation
biological_process
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coe...
[ "GOC:mah", "ISBN:0198506732" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-77289 \"Mitochondrial Fatty Acid Beta-Oxidation\"" ]
[ "GO:0009062", "GO:0019395" ]
[ "has_part GO:0015645" ]
[ "has_part" ]
[ "GO:0015645" ]
[ "GO:0009062", "GO:0015645", "GO:0019395" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28388\" xsd:anyURI" ]
null
null
false
true
2
GO:0006636
6,636
unsaturated fatty acid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
[ "GOC:mah", "MetaCyc:PWY-762", "MetaCyc:PWY-782" ]
null
[ "fatty acid desaturation", "polyunsaturated fatty acid biosynthesis", "unsaturated fatty acid anabolism", "unsaturated fatty acid biosynthesis", "unsaturated fatty acid formation", "unsaturated fatty acid synthesis" ]
[ "RELATED", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-762", "MetaCyc:PWY-782" ]
[ "GO:0006633", "GO:0033559" ]
[]
[]
[]
[ "GO:0006633", "GO:0033559" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch MetaCyc:PWY-762", "skos:narrowMatch MetaCyc:PWY-782", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28527\" xsd:anyURI" ]
null
null
false
true
3
GO:0006637
6,637
acyl-CoA metabolic process
biological_process
The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
[ "ISBN:0198506732" ]
null
[ "acyl-CoA metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006753", "GO:0006790", "GO:0072521" ]
[]
[]
[]
[ "GO:0006753", "GO:0006790", "GO:0072521" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0006638
6,638
neutral lipid metabolic process
biological_process
The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.
[ "ISBN:0198547684" ]
null
[ "neutral lipid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006629" ]
[]
[]
[]
[ "GO:0006629" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28908\" xsd:anyURI" ]
null
null
false
true
8
GO:0006639
6,639
acylglycerol metabolic process
biological_process
The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
[ "ISBN:0198506732" ]
null
[ "acylglycerol metabolism", "glyceride metabolic process", "glyceride metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006638", "GO:0046486" ]
[]
[]
[]
[ "GO:0006638", "GO:0046486" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0006640
6,640
monoacylglycerol biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
[ "ISBN:0198506732" ]
null
[ "monoacylglycerol anabolism", "monoacylglycerol biosynthesis", "monoacylglycerol formation", "monoacylglycerol synthesis", "monoglyceride biosynthesis", "monoglyceride biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046462", "GO:0046463" ]
[]
[]
[]
[ "GO:0046462", "GO:0046463" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006641
6,641
triglyceride metabolic process
biological_process
The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
[ "ISBN:0198506732" ]
null
[ "triacylglycerol metabolic process", "triacylglycerol metabolism", "triglyceride metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-8979227 \"Triglyceride metabolism\"" ]
[ "GO:0006639" ]
[]
[]
[]
[ "GO:0006639" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006642
6,642
triglyceride mobilization
biological_process
The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism.
[ "GOC:mah", "PMID:11943743", "PMID:15713625" ]
null
[ "triacylglycerol mobilization" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006641" ]
[]
[]
[]
[ "GO:0006641" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006643
6,643
obsolete membrane lipid metabolic process
biological_process
OBSOLETE. The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.
[ "GOC:ai" ]
The reason for obsoletion is that this term groups lipids by their localization rather than by their metabolic function, which is problematic since most lipids can function in multiple locations.
[ "membrane lipid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006629" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26698\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28908\" xsd:anyURI" ]
null
null
true
true
2
GO:0006644
6,644
phospholipid metabolic process
biological_process
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
[ "ISBN:0198506732" ]
null
[ "phospholipid metabolism" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1483115 \"Hydrolysis of LPC\"", "Reactome:R-HSA-1483152 \"Hydrolysis of LPE\"", "Reactome:R-HSA-1483257 \"Phospholipid metabolism\"" ]
[ "GO:0006629", "GO:0006796", "GO:0019637" ]
[]
[]
[]
[ "GO:0006629", "GO:0006796", "GO:0019637" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28908\" xsd:anyURI" ]
null
null
false
true
3
GO:0006646
6,646
phosphatidylethanolamine biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
[ "ISBN:0198506732" ]
null
[ "phosphatidylethanolamine anabolism", "phosphatidylethanolamine biosynthesis", "phosphatidylethanolamine formation", "phosphatidylethanolamine synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1483213 \"Synthesis of PE\"" ]
[ "GO:0046337", "GO:0046474" ]
[]
[]
[]
[ "GO:0046337", "GO:0046474" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006647
6,647
phosphatidyl-N-monomethylethanolamine biosynthetic process
biological_process
The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.
[ "PMID:35071223" ]
null
[ "phosphatidyl-N-monomethylethanolamine anabolism", "phosphatidyl-N-monomethylethanolamine biosynthesis", "phosphatidyl-N-monomethylethanolamine formation", "phosphatidyl-N-monomethylethanolamine synthesis", "PMME biosynthesis", "PMME biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006646" ]
[]
[]
[]
[ "GO:0006646" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006648
6,648
dihydrosphingosine-1-P pathway
biological_process
A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase.
[ "GOC:mah", "PMID:15643073" ]
null
[]
[]
[]
[]
[]
[ "GO:0006646" ]
[]
[]
[]
[ "GO:0006646" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006649
6,649
phospholipid transfer to membrane
biological_process
The transfer of a phospholipid from its site of synthesis to the plasma membrane.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0015914" ]
[ "part_of GO:0061024" ]
[ "part_of" ]
[ "GO:0061024" ]
[ "GO:0015914", "GO:0061024" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006650
6,650
glycerophospholipid metabolic process
biological_process
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
[ "ISBN:0198506732" ]
null
[ "alpha-glycerophosphate pathway", "glycerophospholipid metabolism", "phosphoglyceride metabolic process", "phosphoglyceride metabolism" ]
[ "RELATED", "EXACT", "EXACT", "EXACT" ]
[ "GO:0006652" ]
[]
[]
[ "GO:0006644", "GO:0046486" ]
[]
[]
[]
[ "GO:0006644", "GO:0046486" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0006651
6,651
diacylglycerol biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
[ "GOC:curators" ]
null
[ "diacylglycerol anabolism", "diacylglycerol biosynthesis", "diacylglycerol formation", "diacylglycerol synthesis", "diglyceride biosynthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046339", "GO:0046463" ]
[]
[]
[]
[ "GO:0046339", "GO:0046463" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0006655
6,655
phosphatidylglycerol biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.
[ "ISBN:0198506732" ]
null
[ "phosphatidylglycerol anabolism", "phosphatidylglycerol biosynthesis", "phosphatidylglycerol formation", "phosphatidylglycerol synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1483148 \"Synthesis of PG\"" ]
[ "GO:0046471", "GO:0046474" ]
[]
[]
[]
[ "GO:0046471", "GO:0046474" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006656
6,656
phosphatidylcholine biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
[ "ISBN:0198506732" ]
null
[ "phosphatidylcholine anabolism", "phosphatidylcholine biosynthesis", "phosphatidylcholine formation", "phosphatidylcholine synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1483191 \"Synthesis of PC\"" ]
[ "GO:0046470", "GO:0046474" ]
[]
[]
[]
[ "GO:0046470", "GO:0046474" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006657
6,657
CDP-choline pathway
biological_process
The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.
[ "ISBN:0471331309", "MetaCyc:PWY3O-450" ]
null
[ "Kennedy pathway", "phosphatidylcholine biosynthesis from choline" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY3O-450" ]
[ "GO:0006656" ]
[ "has_part GO:0004103", "has_part GO:0004142" ]
[ "has_part", "has_part" ]
[ "GO:0004103", "GO:0004142" ]
[ "GO:0004103", "GO:0004142", "GO:0006656" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0006658
6,658
phosphatidylserine metabolic process
biological_process
The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.
[ "ISBN:0198506732" ]
null
[ "phosphatidylserine metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006575", "GO:0006650" ]
[]
[]
[]
[ "GO:0006575", "GO:0006650" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006660
6,660
phosphatidylserine catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
[ "ISBN:0198506732" ]
null
[ "phosphatidylserine breakdown", "phosphatidylserine catabolism", "phosphatidylserine degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006658", "GO:0042219", "GO:0046475" ]
[]
[]
[]
[ "GO:0006658", "GO:0042219", "GO:0046475" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0006661
6,661
phosphatidylinositol biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
[ "ISBN:0198506732" ]
null
[ "phosphatidylinositol anabolism", "phosphatidylinositol biosynthesis", "phosphatidylinositol formation", "phosphatidylinositol synthesis", "phosphoinositide biosynthesis", "phosphoinositide biosynthetic process", "PtdIns biosynthesis", "PtdIns biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0046489" ]
[]
[ "Reactome:R-HSA-1483226 \"Synthesis of PI\"", "Reactome:R-HSA-1483248 \"Synthesis of PIPs at the ER membrane\"", "Reactome:R-HSA-1660499 \"Synthesis of PIPs at the plasma membrane\"", "Reactome:R-HSA-1660514 \"Synthesis of PIPs at the Golgi membrane\"", "Reactome:R-HSA-1660516 \"Synthesis of PIPs at the ear...
[ "GO:0009058", "GO:0046488" ]
[]
[]
[]
[ "GO:0009058", "GO:0046488" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27059\" xsd:anyURI" ]
null
null
false
true
4
GO:0006662
6,662
obsolete glycerol ether metabolic process
biological_process
OBSOLETE. The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
[ "GOC:ai", "ISBN:0198506732" ]
This term was obsoleted because it is an unnecessary grouping class.
[ "glycerol ether metabolism" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]
null
null
true
true
8
GO:0006663
6,663
platelet activating factor biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
[ "ISBN:0198547684" ]
null
[ "PAF biosynthesis", "PAF biosynthetic process", "platelet activating factor anabolism", "platelet activating factor biosynthesis", "platelet activating factor formation", "platelet activating factor synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008611", "GO:0046469", "GO:0046474" ]
[]
[]
[]
[ "GO:0008611", "GO:0046469", "GO:0046474" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006664
6,664
glycolipid metabolic process
biological_process
The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the gl...
[ "ISBN:0198547684" ]
null
[ "glycolipid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:1903509" ]
[]
[]
[]
[ "GO:1903509" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006665
6,665
sphingolipid metabolic process
biological_process
The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
[ "GOC:mah", "ISBN:0198506732" ]
null
[ "sphingolipid metabolism" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-428157 \"Sphingolipid metabolism\"" ]
[ "GO:0006629" ]
[]
[]
[]
[ "GO:0006629" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0006666
6,666
3-keto-sphinganine metabolic process
biological_process
The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
[ "GOC:ai" ]
null
[ "3-keto-dihydrosphingosine metabolic process", "3-keto-dihydrosphingosine metabolism", "3-keto-sphinganine metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0006667
6,667
sphinganine metabolic process
biological_process
The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.
[ "PMID:29165427" ]
null
[ "dihydrosphingosine metabolic process", "dihydrosphingosine metabolism", "sphinganine metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0034311", "GO:0046519" ]
[]
[]
[]
[ "GO:0034311", "GO:0046519" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006668
6,668
sphinganine-1-phosphate metabolic process
biological_process
The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
[ "GOC:ai" ]
null
[ "dihydrosphingosine-1-phosphate metabolic process", "dihydrosphingosine-1-phosphate metabolism", "sphinganine-1-phosphate metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006644", "GO:0006665" ]
[]
[]
[]
[ "GO:0006644", "GO:0006665" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006669
6,669
sphinganine-1-phosphate biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
[ "GOC:ai" ]
null
[ "dihydrosphingosine-1-phosphate biosynthesis", "dihydrosphingosine-1-phosphate biosynthetic process", "sphinganine-1-phosphate anabolism", "sphinganine-1-phosphate biosynthesis", "sphinganine-1-phosphate formation", "sphinganine-1-phosphate synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006668", "GO:0008654", "GO:0030148" ]
[]
[]
[]
[ "GO:0006668", "GO:0008654", "GO:0030148" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006673
6,673
inositol phosphoceramide metabolic process
biological_process
The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.
[ "PMID:19726565" ]
null
[ "inositol phosphorylceramide metabolic process", "inositol phosphorylceramide metabolism", "inositolphosphoceramide metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[ "GO:0006674" ]
[]
[]
[ "GO:0006644", "GO:0006665" ]
[]
[]
[]
[ "GO:0006644", "GO:0006665" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006675
6,675
mannosyl-inositol phosphorylceramide metabolic process
biological_process
The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.
[ "GOC:ai" ]
null
[ "mannose inositol phosphoceramide metabolic process", "mannose inositol phosphoceramide metabolism", "mannose-inositol-P-ceramide (MIPC) metabolic process", "mannose-inositol-P-ceramide (MIPC) metabolism", "mannosyl-inositol-phosphorylceramide metabolism", "MIPC metabolic process", "MIPC metabolism" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006673", "GO:0006687" ]
[]
[]
[]
[ "GO:0006673", "GO:0006687" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0006676
6,676
mannosyl diphosphorylinositol ceramide metabolic process
biological_process
The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative.
[ "GOC:ai" ]
null
[ "M(IP)2C metabolic process", "M(IP)2C metabolism", "mannosyl diphosphorylinositol ceramide metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006505", "GO:0006673" ]
[]
[]
[]
[ "GO:0006505", "GO:0006673" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006677
6,677
glycosylceramide metabolic process
biological_process
The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
[ "GOC:ai", "ISBN:0198506732" ]
null
[ "glycosylceramide metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006672", "GO:0006687" ]
[]
[]
[]
[ "GO:0006672", "GO:0006687" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006678
6,678
glucosylceramide metabolic process
biological_process
The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.
[ "ISBN:0198506732" ]
null
[ "glucosylceramide metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006677" ]
[]
[]
[]
[ "GO:0006677" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006679
6,679
glucosylceramide biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound composed of a ceramide backbone covalently linked to a glucose. The glucose can be further elongated with the sequential addition of various carbohydrate units.
[ "PMID:35536927" ]
null
[ "glucosylceramide anabolism", "glucosylceramide biosynthesis", "glucosylceramide formation", "glucosylceramide synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006678", "GO:0006688", "GO:0046513" ]
[]
[]
[]
[ "GO:0006678", "GO:0006688", "GO:0046513" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30616\" xsd:anyURI" ]
null
null
false
true
8
GO:0006680
6,680
glucosylceramide catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
[ "GOC:ai" ]
null
[ "glucosylceramide breakdown", "glucosylceramide catabolism", "glucosylceramide degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006678", "GO:0046477" ]
[]
[]
[]
[ "GO:0006678", "GO:0046477" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0006681
6,681
galactosylceramide metabolic process
biological_process
The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
[ "GOC:ai" ]
null
[ "galactosylceramide metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006677", "GO:0019374" ]
[]
[]
[]
[ "GO:0006677", "GO:0019374" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006683
6,683
galactosylceramide catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
[ "GOC:ai" ]
null
[ "galactosylceramide breakdown", "galactosylceramide catabolism", "galactosylceramide degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006681", "GO:0019376", "GO:0046477" ]
[]
[]
[]
[ "GO:0006681", "GO:0019376", "GO:0046477" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006684
6,684
sphingomyelin metabolic process
biological_process
The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
[ "ISBN:0198506732" ]
null
[ "sphingomyelin metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006644", "GO:0006665" ]
[]
[]
[]
[ "GO:0006644", "GO:0006665" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0006685
6,685
sphingomyelin catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
[ "ISBN:0198506732" ]
null
[ "sphingomyelin breakdown", "sphingomyelin catabolism", "sphingomyelin degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006684", "GO:0009395", "GO:0030149" ]
[]
[]
[]
[ "GO:0006684", "GO:0009395", "GO:0030149" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006686
6,686
sphingomyelin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
[ "ISBN:0198506732" ]
null
[ "sphingomyelin anabolism", "sphingomyelin biosynthesis", "sphingomyelin formation", "sphingomyelin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006684", "GO:0008654", "GO:0030148" ]
[]
[]
[]
[ "GO:0006684", "GO:0008654", "GO:0030148" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006687
6,687
glycosphingolipid metabolic process
biological_process
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
[ "ISBN:0198547684" ]
null
[ "glycosphingolipid metabolism" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1660662 \"Glycosphingolipid metabolism\"" ]
[ "GO:0006664", "GO:0006665" ]
[]
[]
[]
[ "GO:0006664", "GO:0006665" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006688
6,688
glycosphingolipid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of a glycosphingolipid, a compound composed of a ceramide backbone covalently linked to at least one carbohydrate moiety.
[ "PMID:35536927" ]
null
[ "glycosphingolipid anabolism", "glycosphingolipid biosynthesis", "glycosphingolipid formation", "glycosphingolipid synthesis", "glycosylceramide biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-9840309 \"Glycosphingolipid biosynthesis\"" ]
[ "GO:0006687", "GO:0009247", "GO:0030148" ]
[]
[]
[]
[ "GO:0006687", "GO:0009247", "GO:0030148" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30616\" xsd:anyURI" ]
null
null
false
true
2
GO:0006689
6,689
ganglioside catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
[ "ISBN:0198547684" ]
null
[ "ganglioside breakdown", "ganglioside catabolism", "ganglioside degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001573", "GO:0046479", "GO:0046514" ]
[]
[]
[]
[ "GO:0001573", "GO:0046479", "GO:0046514" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006690
6,690
icosanoid metabolic process
biological_process
The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
[ "GOC:ma" ]
null
[ "eicosanoid metabolic process", "eicosanoid metabolism", "icosanoid metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-211979 \"Eicosanoids\"" ]
[ "GO:0019752" ]
[]
[]
[]
[ "GO:0019752" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006691
6,691
leukotriene metabolic process
biological_process
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
[ "GOC:ma" ]
null
[ "leukotriene metabolism" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-2142691 \"Synthesis of Leukotrienes (LT) and Eoxins (EX)\"" ]
[ "GO:0006690" ]
[]
[]
[]
[ "GO:0006690" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0006692
6,692
prostanoid metabolic process
biological_process
The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.
[ "ISBN:0198506732" ]
null
[ "prostanoid metabolism" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-140180 \"COX reactions\"" ]
[ "GO:0006690", "GO:0033559" ]
[]
[]
[]
[ "GO:0006690", "GO:0033559" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006693
6,693
prostaglandin metabolic process
biological_process
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
[ "ISBN:0198506732" ]
null
[ "prostaglandin metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006692" ]
[]
[]
[]
[ "GO:0006692" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006694
6,694
steroid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
[ "GOC:curators" ]
null
[ "steroid anabolism", "steroid biosynthesis", "steroid formation", "steroid synthesis", "steroidogenesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Wikipedia:Steroid_metabolisms#Steroid_biosynthesis" ]
[ "GO:0008202", "GO:0008610" ]
[]
[]
[]
[ "GO:0008202", "GO:0008610" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006695
6,695
cholesterol biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
[ "GOC:ai" ]
null
[ "cholesterol anabolism", "cholesterol biosynthesis", "cholesterol formation", "cholesterol synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-191273 \"Cholesterol biosynthesis\"" ]
[ "GO:0008203", "GO:0016126", "GO:1902653" ]
[]
[]
[]
[ "GO:0008203", "GO:0016126", "GO:1902653" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0006696
6,696
ergosterol biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
[ "ISBN:0198506732" ]
null
[ "ergosterol anabolism", "ergosterol biosynthesis", "ergosterol formation", "ergosterol synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008204", "GO:0016126", "GO:0016129", "GO:1902653" ]
[]
[]
[]
[ "GO:0008204", "GO:0016126", "GO:0016129", "GO:1902653" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28908\" xsd:anyURI" ]
null
null
false
true
2
GO:0006697
6,697
ecdysone biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
[ "ISBN:0198506732" ]
null
[ "ecdysone anabolism", "ecdysone biosynthesis", "ecdysone formation", "ecdysone synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008205", "GO:0016126", "GO:0045456", "GO:1902653" ]
[]
[]
[]
[ "GO:0008205", "GO:0016126", "GO:0045456", "GO:1902653" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006698
6,698
obsolete ecdysone modification
biological_process
OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties.
[ "GOC:jl" ]
This term was made obsolete because it was created to cover the conversion of ecdysone to its active form ecdysterone (20-hydroxyecdysone), but this reaction is carried out in a single step by ecdysone 20-monooxygenase (EC:1.14.99.22) and so is a function rather than a process.
[ "ecdysone modification" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0004501" ]
[]
[]
null
null
true
true
1
GO:0006699
6,699
bile acid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
[ "GOC:curators" ]
null
[ "bile acid anabolism", "bile acid biosynthesis", "bile acid formation", "bile acid synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-192105 \"Synthesis of bile acids and bile salts\"" ]
[ "GO:0008206", "GO:0072330" ]
[]
[]
[]
[ "GO:0008206", "GO:0072330" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006701
6,701
progesterone biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
[ "GOC:jl", "PMID:14613534" ]
null
[ "progesterone anabolism", "progesterone biosynthesis", "progesterone formation", "progesterone synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006700", "GO:0042181", "GO:0042448", "GO:0120255" ]
[]
[]
[]
[ "GO:0006700", "GO:0042181", "GO:0042448", "GO:0120255" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0006702
6,702
androgen biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
[ "ISBN:0198506732" ]
null
[ "androgen anabolism", "androgen biosynthesis", "androgen formation", "androgen synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-193048 \"Androgen biosynthesis\"" ]
[ "GO:0008209", "GO:0042446", "GO:0120178" ]
[]
[]
[]
[ "GO:0008209", "GO:0042446", "GO:0120178" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006703
6,703
estrogen biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
[ "ISBN:0198506732" ]
null
[ "estrogen anabolism", "estrogen biosynthesis", "estrogen formation", "estrogen synthesis", "oestrogen biosynthesis", "oestrogen biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-193144 \"Estrogen biosynthesis\"" ]
[ "GO:0008210", "GO:0042446", "GO:0120178" ]
[]
[]
[]
[ "GO:0008210", "GO:0042446", "GO:0120178" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0006704
6,704
glucocorticoid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
[ "ISBN:0198506732" ]
null
[ "glucocorticoid anabolism", "glucocorticoid biosynthesis", "glucocorticoid formation", "glucocorticoid synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-194002 \"Glucocorticoid biosynthesis\"" ]
[ "GO:0008211", "GO:0120178" ]
[]
[]
[]
[ "GO:0008211", "GO:0120178" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0006705
6,705
mineralocorticoid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
[ "ISBN:0198506732" ]
null
[ "mineralocorticoid anabolism", "mineralocorticoid biosynthesis", "mineralocorticoid formation", "mineralocorticoid synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-193993 \"Mineralocorticoid biosynthesis\"" ]
[ "GO:0008212", "GO:0042446", "GO:0120178" ]
[]
[]
[]
[ "GO:0008212", "GO:0042446", "GO:0120178" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006706
6,706
steroid catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
[ "GOC:curators" ]
null
[ "steroid breakdown", "steroid catabolism", "steroid degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008202", "GO:0016042" ]
[]
[]
[]
[ "GO:0008202", "GO:0016042" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006707
6,707
cholesterol catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
[ "GOC:ai" ]
null
[ "cholesterol breakdown", "cholesterol catabolism", "cholesterol degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008203", "GO:0016127", "GO:0046164" ]
[]
[]
[]
[ "GO:0008203", "GO:0016127", "GO:0046164" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0006708
6,708
ecdysone catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
[ "ISBN:0198506732" ]
null
[ "ecdysone breakdown", "ecdysone catabolism", "ecdysone degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008205", "GO:0016127", "GO:0046164", "GO:0046344" ]
[]
[]
[]
[ "GO:0008205", "GO:0016127", "GO:0046164", "GO:0046344" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006709
6,709
progesterone catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
[ "GOC:jl", "PMID:11392024" ]
null
[ "progesterone breakdown", "progesterone catabolism", "progesterone degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008208", "GO:0042182", "GO:0042448", "GO:0120256" ]
[]
[]
[]
[ "GO:0008208", "GO:0042182", "GO:0042448", "GO:0120256" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006710
6,710
androgen catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
[ "ISBN:0198506732" ]
null
[ "androgen breakdown", "androgen catabolism", "androgen degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006706", "GO:0008209", "GO:0042447" ]
[]
[]
[]
[ "GO:0006706", "GO:0008209", "GO:0042447" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006711
6,711
estrogen catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
[ "ISBN:0198506732" ]
null
[ "estrogen breakdown", "estrogen catabolism", "estrogen degradation", "oestrogen catabolic process", "oestrogen catabolism" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006706", "GO:0008210", "GO:0042447" ]
[]
[]
[]
[ "GO:0006706", "GO:0008210", "GO:0042447" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006712
6,712
mineralocorticoid catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
[ "ISBN:0198506732" ]
null
[ "mineralocorticoid breakdown", "mineralocorticoid catabolism", "mineralocorticoid degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006706", "GO:0008212", "GO:0042447" ]
[]
[]
[]
[ "GO:0006706", "GO:0008212", "GO:0042447" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0006713
6,713
glucocorticoid catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
[ "ISBN:0198506732" ]
null
[ "glucocorticoid breakdown", "glucocorticoid catabolism", "glucocorticoid degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006706", "GO:0008211" ]
[]
[]
[]
[ "GO:0006706", "GO:0008211" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0006714
6,714
sesquiterpenoid metabolic process
biological_process
The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.
[ "ISBN:0198547684" ]
null
[ "sesquiterpenoid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006721" ]
[]
[]
[]
[ "GO:0006721" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0006715
6,715
farnesol biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
[ "ISBN:0198547684" ]
null
[ "farnesol anabolism", "farnesol biosynthesis", "farnesol formation", "farnesol synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016094", "GO:0016106", "GO:0016487", "GO:0034309" ]
[]
[]
[]
[ "GO:0016094", "GO:0016106", "GO:0016487", "GO:0034309" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0006716
6,716
juvenile hormone metabolic process
biological_process
The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
[ "GOC:curators", "ISBN:0198547684" ]
null
[ "juvenile hormone metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006714", "GO:0042445" ]
[]
[]
[]
[ "GO:0006714", "GO:0042445" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0006717
6,717
obsolete juvenile hormone binding
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:curators" ]
This term was made obsolete because it represents a molecular function and not a biological process.
[ "juvenile hormone binding" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0005500" ]
[]
null
null
true
true
4
GO:0006718
6,718
juvenile hormone biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
[ "GOC:curators", "ISBN:0198547684" ]
null
[ "juvenile hormone anabolism", "juvenile hormone biosynthesis", "juvenile hormone formation", "juvenile hormone synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006716", "GO:0016106", "GO:0042446" ]
[]
[]
[]
[ "GO:0006716", "GO:0016106", "GO:0042446" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0006719
6,719
juvenile hormone catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
[ "GOC:curators", "ISBN:0198547684" ]
null
[ "juvenile hormone breakdown", "juvenile hormone catabolism", "juvenile hormone degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006716", "GO:0016107", "GO:0042447" ]
[]
[]
[]
[ "GO:0006716", "GO:0016107", "GO:0042447" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0006720
6,720
isoprenoid metabolic process
biological_process
The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
[ "ISBN:0198547684" ]
null
[ "isoprenoid metabolism", "polyisoprenoid metabolic process", "polyisoprenoid metabolism", "polyterpene metabolic process", "polyterpene metabolism" ]
[ "EXACT", "NARROW", "NARROW", "NARROW", "NARROW" ]
[ "GO:0016096" ]
[]
[]
[ "GO:0006629" ]
[]
[]
[]
[ "GO:0006629" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28908\" xsd:anyURI" ]
null
null
false
true
8
GO:0006721
6,721
terpenoid metabolic process
biological_process
The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.
[ "ISBN:0198506732" ]
null
[ "terpenoid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006720" ]
[]
[]
[]
[ "GO:0006720" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0006723
6,723
cuticle hydrocarbon biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
[ "GOC:ai" ]
null
[ "cuticle hydrocarbon anabolism", "cuticle hydrocarbon biosynthesis", "cuticle hydrocarbon formation", "cuticle hydrocarbon synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0120251" ]
[ "part_of GO:0042335" ]
[ "part_of" ]
[ "GO:0042335" ]
[ "GO:0042335", "GO:0120251" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0006726
6,726
eye pigment biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
[ "GOC:ai" ]
null
[ "eye pigment anabolism", "eye pigment biosynthesis", "eye pigment formation", "eye pigment synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0042441", "GO:0046148" ]
[]
[]
[]
[ "GO:0042441", "GO:0046148" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0006727
6,727
ommochrome biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
[ "ISBN:0198506732" ]
null
[ "ommochrome anabolism", "ommochrome biosynthesis", "ommochrome formation", "ommochrome synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006726", "GO:0008055", "GO:0046152" ]
[]
[]
[]
[ "GO:0006726", "GO:0008055", "GO:0046152" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4