prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of PRC1 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 815 | Knockout | PRC1 | cell proliferation | Colonic Cancer Cell Line | Gene: PRC1 (protein regulator of cytokinesis 1)
Type: protein-coding
Summary: This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. I... |
Does Knockout of HOXD8 in Prostate Cancer Cell Line causally result in cell proliferation? | 0 | 843 | Knockout | HOXD8 | cell proliferation | Prostate Cancer Cell Line | Gene: HOXD8 (homeobox D8)
Type: protein-coding
Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene ... |
Does Knockout of UQCRQ in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | UQCRQ | cell proliferation | Multiple Myeloma Cell Line | Gene: UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII)
Type: protein-coding
Summary: This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the m... |
Does Knockout of DBN1 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,430 | Knockout | DBN1 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: DBN1 (drebrin 1)
Type: protein-coding
Summary: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amoun... |
Does Knockout of ACTB in Glioma Cell Line causally result in protein/peptide accumulation? | 1 | 589 | Knockout | ACTB | protein/peptide accumulation | Glioma Cell Line | Gene: ACTB (actin beta)
Type: protein-coding
Summary: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus... |
Does Knockout of KLHDC10 in Breast Cancer Cell Line causally result in cell proliferation? | 0 | 235 | Knockout | KLHDC10 | cell proliferation | Breast Cancer Cell Line | Gene: KLHDC10 (kelch domain containing 10)
Type: protein-coding
Summary: Enables ubiquitin ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in nucleoplasm. Is active in Cul2-RING ubiquitin ligase complex. [provided by... |
Does Knockout of ZFC3H1 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | ZFC3H1 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: ZFC3H1 (zinc finger C3H1-type containing)
Type: protein-coding
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in RNA processing. Located in nucleus. Part of exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: ... |
Does Knockout of DPH5 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | DPH5 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: DPH5 (diphthamide biosynthesis 5)
Type: protein-coding
Summary: This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is ... |
Does Knockout of BDKRB2 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 1,352 | Knockout | BDKRB2 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: BDKRB2 (bradykinin receptor B2)
Type: protein-coding
Summary: This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic co... |
Does Knockout of TBC1D3F in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | TBC1D3F | cell proliferation | Colorectal Cancer Cell Line | Gene: TBC1D3F (TBC1 domain family member 3F)
Type: protein-coding
Summary: Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, ... |
Does Knockout of C3orf18 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | C3orf18 | cell proliferation | Glioblastoma Cell Line | Gene: C3orf18 (chromosome 3 open reading frame 18)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
UniProt: Q9UK00
Entrez ID: 51161 |
Does Activation of ABHD15 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | ABHD15 | protein/peptide accumulation | T cell | Gene: ABHD15 (abhydrolase domain containing 15)
Type: protein-coding
Summary: Predicted to enable acylglycerol lipase activity and short-chain carboxylesterase activity. Predicted to be involved in cellular lipid metabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022... |
Does Knockout of EIF2B1 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | EIF2B1 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha)
Type: protein-coding
Summary: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis.... |
Does Knockout of PGAM1 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 1,813 | Knockout | PGAM1 | cell proliferation | Medulloblastoma Cell Line | Gene: PGAM1 (phosphoglycerate mutase 1)
Type: protein-coding
Summary: The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been f... |
Does Knockout of OTOP1 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | OTOP1 | cell proliferation | Colorectal Cancer Cell Line | Gene: OTOP1 (otopetrin 1)
Type: protein-coding
Summary: This gene encodes a transmembrane protein which belongs to the otopetrin domain protein family and is required for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals that are required for the detec... |
Does Knockout of TRIM28 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | TRIM28 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: TRIM28 (tripartite motif containing 28)
Type: protein-coding
Summary: The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to assoc... |
Does Knockout of NUF2 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | NUF2 | cell proliferation | Glioblastoma Cell Line | Gene: NUF2 (NUF2 component of NDC80 kinetochore complex)
Type: protein-coding
Summary: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centr... |
Does Knockout of PAK1IP1 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | PAK1IP1 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: PAK1IP1 (PAK1 interacting protein 1)
Type: protein-coding
Summary: Involved in regulation of signal transduction by p53 class mediator and ribosomal large subunit biogenesis. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: cell population prol... |
Does Knockout of HOXD1 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | HOXD1 | cell proliferation | Cancer Cell Line | Gene: HOXD1 (homeobox D1)
Type: protein-coding
Summary: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutatio... |
Does Knockout of TCFL5 in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | TCFL5 | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: TCFL5 (transcription factor like 5)
Type: protein-coding
Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of tra... |
Does Knockout of KRT82 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 0 | 1,978 | Knockout | KRT82 | response to chemicals | Monocytic Leukemia Cell Line | Gene: KRT82 (keratin 82)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chrom... |
Does Knockout of TRAPPC3 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | TRAPPC3 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: TRAPPC3 (trafficking protein particle complex subunit 3)
Type: protein-coding
Summary: This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the end... |
Does Knockout of NFYC in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 897 | Knockout | NFYC | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: NFYC (nuclear transcription factor Y subunit gamma)
Type: protein-coding
Summary: This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subuni... |
Does Knockout of DPPA3 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 897 | Knockout | DPPA3 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: DPPA3 (developmental pluripotency associated 3)
Type: protein-coding
Summary: This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance... |
Does Knockout of DNAJC14 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 1,311 | Knockout | DNAJC14 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: DNAJC14 (DnaJ heat shock protein family (Hsp40) member C14)
Type: protein-coding
Summary: Predicted to be involved in protein transport. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: G protein-coupled receptor binding, dopamine receptor bindi... |
Does Inhibition of MED16 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 1 | 1,184 | Inhibition | MED16 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: MED16 (mediator complex subunit 16)
Type: protein-coding
Summary: Enables thyroid hormone receptor binding activity and transcription coactivator activity. Involved in positive regulation of transcription initiation from RNA polymerase II promoter. Located in membrane. Part of mediator complex. [p... |
Does Knockout of SLFN12 in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | SLFN12 | cell proliferation | T-lymphoma cell line | Gene: SLFN12 (schlafen family member 12)
Type: protein-coding
Summary: Predicted to act upstream of or within negative regulation of cell population proliferation. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: apoptotic signaling pathway, rRNA catabolic process; MF: RN... |
Does Knockout of SERINC2 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | SERINC2 | cell proliferation | Gastric Cancer Cell Line | Gene: SERINC2 (serine incorporator 2)
Type: protein-coding
Summary: Predicted to be involved in several processes, including phosphatidylserine metabolic process; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity; and positive regulation of serine C-palmitoyltransferase... |
Does Knockout of NF2 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | NF2 | cell proliferation | Melanoma Cell Line | Gene: NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor)
Type: protein-coding
Summary: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein ... |
Does Knockout of LDLRAD2 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 1,352 | Knockout | LDLRAD2 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: LDLRAD2 (low density lipoprotein receptor class A domain containing 2)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
UniProt: Q5SZI1
Entrez ID: 401944 |
Does Knockout of GREM2 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 0 | 180 | Knockout | GREM2 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: GREM2 (gremlin 2, DAN family BMP antagonist)
Type: protein-coding
Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP ant... |
Does Knockout of PSMD6 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | PSMD6 | cell proliferation | Colorectal Cancer Cell Line | Gene: PSMD6 (proteasome 26S subunit, non-ATPase 6)
Type: protein-coding
Summary: This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated pr... |
Does Knockout of TAPT1 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | TAPT1 | cell proliferation | Glioblastoma Cell Line | Gene: TAPT1 (transmembrane anterior posterior transformation 1)
Type: protein-coding
Summary: This gene encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in this gene disrupt Golgi morphology and trafficking and normal primary cilium formation and t... |
Does Knockout of GNL2 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | GNL2 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: GNL2 (G protein nucleolar 2)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: GTP binding, GTPase activity, RNA binding, nucleotide bin... |
Does Knockout of DCXR in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 734 | Knockout | DCXR | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: DCXR (dicarbonyl and L-xylulose reductase)
Type: protein-coding
Summary: The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osm... |
Does Knockout of MFSD6L in Melanoma Cell Line causally result in response to chemicals? | 1 | 1,940 | Knockout | MFSD6L | response to chemicals | Melanoma Cell Line | Gene: MFSD6L (major facilitator superfamily domain containing 6 like)
Type: protein-coding
Summary: Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: membrane
Pathways:
U... |
Does Knockout of CXCL17 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 305 | Knockout | CXCL17 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: CXCL17 (C-X-C motif chemokine ligand 17)
Type: protein-coding
Summary: The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this prot... |
Does Knockout of PLA2G6 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | PLA2G6 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: PLA2G6 (phospholipase A2 group VI)
Type: protein-coding
Summary: The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leuko... |
Does Knockout of VIRMA in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | VIRMA | cell proliferation | Medulloblastoma Cell Line | Gene: VIRMA (vir like m6A methyltransferase associated)
Type: protein-coding
Summary: Enables RNA binding activity. Involved in mRNA alternative polyadenylation and mRNA methylation. Located in cytosol and nuclear speck. Colocalizes with RNA N6-methyladenosine methyltransferase complex. [provided by All... |
Does Knockout of NUP133 in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | NUP133 | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: NUP133 (nucleoporin 133)
Type: protein-coding
Summary: The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of mac... |
Does Knockout of RTN4IP1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,789 | Knockout | RTN4IP1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: RTN4IP1 (reticulon 4 interacting protein 1)
Type: protein-coding
Summary: This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neuri... |
Does Knockout of SH3BP1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,459 | Knockout | SH3BP1 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: SH3BP1 (SH3 domain binding protein 1)
Type: protein-coding
Summary: This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein'... |
Does Knockout of TMEM86B in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | TMEM86B | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: TMEM86B (transmembrane protein 86B)
Type: protein-coding
Summary: Enables alkenylglycerophosphocholine hydrolase activity; alkenylglycerophosphoethanolamine hydrolase activity; and identical protein binding activity. Involved in ether lipid metabolic process. Located in cytoplasm and membrane. [pr... |
Does Activation of TRNP1 in Hepatoma Cell Line causally result in response to virus? | 1 | 1,210 | Activation | TRNP1 | response to virus | Hepatoma Cell Line | Gene: TRNP1 (TMF1 regulated nuclear protein 1)
Type: protein-coding
Summary: Predicted to enable DNA binding activity. Predicted to be involved in several processes, including cerebellar cortex morphogenesis; neural precursor cell proliferation; and regulation of cell population proliferation. Predicted... |
Does Knockout of PHYHIPL in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 1,311 | Knockout | PHYHIPL | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)
Type: protein-coding
Summary: Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: cytoplasm
Pathways:
UniProt: Q96FC7
Entrez ID: 84457 |
Does Knockout of PRELID1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | PRELID1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: PRELID1 (PRELI domain containing 1)
Type: protein-coding
Summary: This gene encodes a member of the late embryogenesis abundant motif-containing protein family. The encoded protein is localized to mitochondria and may function as a cytoprotectant by regulating cell death and differentiation. Alter... |
Does Knockout of UBQLN3 in Ovarian Cancer Cell Line causally result in cell proliferation? | 0 | 699 | Knockout | UBQLN3 | cell proliferation | Ovarian Cancer Cell Line | Gene: UBQLN3 (ubiquilin 3)
Type: protein-coding
Summary: This gene encodes a ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They ... |
Does Knockout of DHRS12 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | DHRS12 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: DHRS12 (dehydrogenase/reductase 12)
Type: protein-coding
Summary: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandi... |
Does Knockout of NUCB1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | NUCB1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: NUCB1 (nucleobindin 1)
Type: protein-coding
Summary: This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010].
... |
Does Knockout of C21orf58 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,576 | Knockout | C21orf58 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: C21orf58 (chromosome 21 open reading frame 58)
Type: protein-coding
Summary: chromosome 21 open reading frame 58
Gene Ontology:
Pathways:
UniProt: P58505
Entrez ID: 54058 |
Does Knockout of HUWE1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | HUWE1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1)
Type: protein-coding
Summary: This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquiti... |
Does Knockout of CENPW in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | CENPW | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: CENPW (centromere protein W)
Type: protein-coding
Summary: Predicted to enable DNA binding activity and protein heterodimerization activity. Involved in chromosome segregation; kinetochore assembly; and mitotic cell cycle. Located in kinetochore and nucleoplasm. [provided by Alliance of Genome Res... |
Does Knockout of CEBPZ in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | CEBPZ | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: CEBPZ (CCAAT enhancer binding protein zeta)
Type: protein-coding
Summary: This gene belongs to the CBF/Mak21 family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock... |
Does Knockout of RHOBTB1 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 0 | 180 | Knockout | RHOBTB1 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: RHOBTB1 (Rho related BTB domain containing 1)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a c... |
Does Knockout of MON1A in Colorectal Cancer Cell Line causally result in response to chemicals? | 0 | 1,414 | Knockout | MON1A | response to chemicals | Colorectal Cancer Cell Line | Gene: MON1A (MON1 vesicular trafficking associated A)
Type: protein-coding
Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in protein secretion. Predicted to act upstream of or within cellular iron ion homeostasis and protein transport. Part of Mon1-Ccz1 complex. [p... |
Does Knockout of VDAC3 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 1,813 | Knockout | VDAC3 | cell proliferation | Medulloblastoma Cell Line | Gene: VDAC3 (voltage dependent anion channel 3)
Type: protein-coding
Summary: This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other sm... |
Does Knockout of APH1A in Astrocytoma Cell Line causally result in cell proliferation? | 0 | 904 | Knockout | APH1A | cell proliferation | Astrocytoma Cell Line | Gene: APH1A (aph-1A gamma-secretase subunit)
Type: protein-coding
Summary: This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paral... |
Does Knockout of PRPH in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | PRPH | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: PRPH (peripherin)
Type: protein-coding
Summary: This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that t... |
Does Knockout of TMEM41B in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | TMEM41B | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: TMEM41B (transmembrane protein 41B)
Type: protein-coding
Summary: Involved in autophagosome assembly. Located in endoplasmic reticulum membrane and mitochondria-associated endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: autophagosome... |
Does Knockout of COX15 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | COX15 | cell proliferation | Monocytic Leukemia Cell Line | Gene: COX15 (cytochrome c oxidase assembly factor COX15)
Type: protein-coding
Summary: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 c... |
Does Knockout of UPF2 in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | UPF2 | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: UPF2 (UPF2 regulator of nonsense mediated mRNA decay)
Type: protein-coding
Summary: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading fram... |
Does Knockout of MANSC1 in Cancer Cell Line causally result in cell proliferation? | 0 | 1,308 | Knockout | MANSC1 | cell proliferation | Cancer Cell Line | Gene: MANSC1 (MANSC domain containing 1)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: Golgi apparatus, membrane
Pathways:
UniProt: Q9H8J5
Entrez ID: 54682 |
Does Knockout of MT1A in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | MT1A | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: MT1A (metallothionein 1A)
Type: protein-coding
Summary: This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-... |
Does Activation of ITGA8 in Hepatoma Cell Line causally result in response to virus? | 1 | 1,210 | Activation | ITGA8 | response to virus | Hepatoma Cell Line | Gene: ITGA8 (integrin subunit alpha 8)
Type: protein-coding
Summary: Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and be... |
Does Knockout of ADAM33 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,340 | Knockout | ADAM33 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: ADAM33 (ADAM metallopeptidase domain 33)
Type: protein-coding
Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a var... |
Does Knockout of SRM in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | SRM | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: SRM (spermidine synthase)
Type: protein-coding
Summary: The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of s... |
Does Knockout of ATP7A in Hepatoma Cell Line causally result in cell proliferation? | 0 | 1,206 | Knockout | ATP7A | cell proliferation | Hepatoma Cell Line | Gene: ATP7A (ATPase copper transporting alpha)
Type: protein-coding
Summary: This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secr... |
Does Activation of LOC105377134 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | LOC105377134 | protein/peptide accumulation | T cell | Gene: LOC105377134 (uncharacterized LOC105377134)
Type: ncRNA
Summary: uncharacterized LOC105377134
Gene Ontology:
Pathways:
UniProt:
Entrez ID: 105377134 |
Does Knockout of LAS1L in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 865 | Knockout | LAS1L | cell proliferation | Colonic Cancer Cell Line | Gene: LAS1L (LAS1 like ribosome biogenesis factor)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Located in membrane. Part of MLL1 complex. Implicated in Wilson-Turner syndrome. [provided by Alliance of Genome ... |
Does Knockout of FECH in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | FECH | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: FECH (ferrochelatase)
Type: protein-coding
Summary: The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic proto... |
Does Knockout of SLC9C1 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,430 | Knockout | SLC9C1 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: SLC9C1 (solute carrier family 9 member C1)
Type: protein-coding
Summary: SLC9A10 is a member of the sodium-hydrogen exchanger (NHE) family (see SLC9A1, MIM 107310) and is required for male fertility and sperm motility (Wang et al., 2003 [PubMed 14634667]).[supplied by OMIM, Apr 2009]
Gene... |
Does Knockout of OTUD4 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | OTUD4 | cell proliferation | Colonic Cancer Cell Line | Gene: OTUD4 (OTU deubiquitinase 4)
Type: protein-coding
Summary: Alternatively spliced transcript variants have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV-1 infected cells. [provided by RefSeq, Jul 2010].
Gene Ontology: B... |
Does Knockout of METTL14 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | METTL14 | cell proliferation | Gastric Cancer Cell Line | Gene: METTL14 (methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit)
Type: protein-coding
Summary: Enables mRNA binding activity. Contributes to mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA metabolic process; negative regulation of hematopoietic prog... |
Does Knockout of ENPEP in Hepatoma Cell Line causally result in cell proliferation? | 0 | 1,206 | Knockout | ENPEP | cell proliferation | Hepatoma Cell Line | Gene: ENPEP (glutamyl aminopeptidase)
Type: protein-coding
Summary: The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can ... |
Does Knockout of MTG1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | MTG1 | cell proliferation | Melanoma Cell Line | Gene: MTG1 (mitochondrial ribosome associated GTPase 1)
Type: protein-coding
Summary: Enables GTPase activity. Involved in regulation of mitochondrial translation and regulation of respiratory system process. Located in mitochondrial inner membrane and mitochondrial ribosome. [provided by Alliance of Ge... |
Does Knockout of SDC2 in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | SDC2 | cell proliferation | Colorectal Cancer Cell Line | Gene: SDC2 (syndecan 2)
Type: protein-coding
Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors ar... |
Does Knockout of KAAG1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 865 | Knockout | KAAG1 | cell proliferation | Colonic Cancer Cell Line | Gene: KAAG1 (kidney associated DCDC2 antisense RNA 1)
Type: ncRNA
Summary: Predicted to be involved in immune response. [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontology:
Pathways:
UniProt:
Entrez ID: 353219 |
Does Knockout of NISCH in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | NISCH | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: NISCH (nischarin)
Type: protein-coding
Summary: This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migrati... |
Does Knockout of TVP23A in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | TVP23A | cell proliferation | Colonic Cancer Cell Line | Gene: TVP23A (trans-golgi network vesicle protein 23 homolog A)
Type: protein-coding
Summary: This gene encodes a membrane protein associated with the Golgi apparatus, which plays a crucial role in intracellular vesicular transport. The encoded protein is likely associated with the late (trans) Golgi co... |
Does Knockout of BUB1 in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | BUB1 | cell proliferation | Breast Cancer Cell Line | Gene: BUB1 (BUB1 mitotic checkpoint serine/threonine kinase)
Type: protein-coding
Summary: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindl... |
Does Knockout of RRM1 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | RRM1 | cell proliferation | Colorectal Cancer Cell Line | Gene: RRM1 (ribonucleotide reductase catalytic subunit M1)
Type: protein-coding
Summary: This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is importa... |
Does Knockout of PITRM1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | PITRM1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: PITRM1 (pitrilysin metallopeptidase 1)
Type: protein-coding
Summary: The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible r... |
Does Knockout of GTF2H2C in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | GTF2H2C | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: GTF2H2C (GTF2H2 family member C)
Type: protein-coding
Summary: Predicted to enable zinc ion binding activity. Predicted to be involved in nucleotide-excision repair and regulation of transcription by RNA polymerase II. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of VPS35 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | VPS35 | cell proliferation | Endometrial Cancer Cell Line | Gene: VPS35 (VPS35 retromer complex component)
Type: protein-coding
Summary: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to... |
Does Knockout of CMC2 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | CMC2 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: CMC2 (C-X9-C motif containing 2)
Type: protein-coding
Summary: Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: cytosol, mitochondrion
Pathways: Mitochondrial protein import, Protein localization
UniProt: Q9NRP2
En... |
Does Activation of SLC35B1 in T cell causally result in protein/peptide accumulation? | 0 | 2,425 | Activation | SLC35B1 | protein/peptide accumulation | T cell | Gene: SLC35B1 (solute carrier family 35 member B1)
Type: protein-coding
Summary: This gene encodes a nucleotide sugar transporter which is a member of solute carrier family 35. The transporters in this family are highly conserved hydrophobic proteins with multiple transmembrane domains. Alternative spli... |
Does Knockout of TRIM56 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 1,510 | Knockout | TRIM56 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: TRIM56 (tripartite motif containing 56)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of macromolecule metabolic process; and protein K63-linked ubiquitination. Predicted ... |
Does Knockout of OXA1L in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | OXA1L | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: OXA1L (OXA1L mitochondrial inner membrane insertase)
Type: protein-coding
Summary: This gene encodes an evolutionarily conserved protein that is localized to the inner mitochondrial membrane. The encoded protein is essential for the translocation of the N-terminal tail of subunit 2 of cytochrome c... |
Does Activation of DMAP1 in Hepatoma Cell Line causally result in response to virus? | 0 | 1,210 | Activation | DMAP1 | response to virus | Hepatoma Cell Line | Gene: DMAP1 (DNA methyltransferase 1 associated protein 1)
Type: protein-coding
Summary: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci t... |
Does Knockout of MYO1H in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | MYO1H | cell proliferation | Mammary Gland Tumor Cell Line | Gene: MYO1H (myosin IH)
Type: protein-coding
Summary: Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be part of myosin complex. Predicted to be active i... |
Does Knockout of UROS in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | UROS | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: UROS (uroporphyrinogen III synthase)
Type: protein-coding
Summary: The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease). [provided by RefSeq, Jul 200... |
Does Knockout of INTS5 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | INTS5 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: INTS5 (integrator complex subunit 5)
Type: protein-coding
Summary: The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processi... |
Does Knockout of CCDC185 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | CCDC185 | cell proliferation | Cancer Cell Line | Gene: CCDC185 (coiled-coil domain containing 185)
Type: protein-coding
Summary: coiled-coil domain containing 185
Gene Ontology:
Pathways:
UniProt: Q8N715
Entrez ID: 164127 |
Does Knockout of NEB in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | NEB | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: NEB (nebulin)
Type: protein-coding
Summary: This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein.... |
Does Knockout of USP54 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 1,813 | Knockout | USP54 | cell proliferation | Medulloblastoma Cell Line | Gene: USP54 (ubiquitin specific peptidase 54)
Type: protein-coding
Summary: Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: protein deubiquitination, proteolysis; MF... |
Does Knockout of SLC25A31 in Multiple Myeloma Cell Line causally result in cell proliferation? | 0 | 816 | Knockout | SLC25A31 | cell proliferation | Multiple Myeloma Cell Line | Gene: SLC25A31 (solute carrier family 25 member 31)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apop... |
Does Knockout of GGACT in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | GGACT | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: GGACT (gamma-glutamylamine cyclotransferase)
Type: protein-coding
Summary: The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the en... |
Does Knockout of ZNF497 in Lung Cancer Cell Line causally result in cell proliferation? | 1 | 674 | Knockout | ZNF497 | cell proliferation | Lung Cancer Cell Line | Gene: ZNF497 (zinc finger protein 497)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted t... |
Does Knockout of MAT2A in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 897 | Knockout | MAT2A | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: MAT2A (methionine adenosyltransferase 2A)
Type: protein-coding
Summary: The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011].
Gene Ontology: ... |
Does Knockout of NOL6 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | NOL6 | cell proliferation | Endometrial Cancer Cell Line | Gene: NOL6 (nucleolar protein 6)
Type: protein-coding
Summary: The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNas... |
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