prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of CIAPIN1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | CIAPIN1 | cell proliferation | Endometrial Cancer Cell Line | Gene: CIAPIN1 (cytokine induced apoptosis inhibitor 1)
Type: protein-coding
Summary: CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor sti... |
Does Knockout of SART1 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | SART1 | cell proliferation | Medulloblastoma Cell Line | Gene: SART1 (spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP)
Type: protein-coding
Summary: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. ... |
Does Knockout of MAP4 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | MAP4 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: MAP4 (microtubule associated protein 4)
Type: protein-coding
Summary: The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule... |
Does Knockout of NCBP1 in Cancer Cell Line causally result in cell proliferation? | 1 | 948 | Knockout | NCBP1 | cell proliferation | Cancer Cell Line | Gene: NCBP1 (nuclear cap binding protein subunit 1)
Type: protein-coding
Summary: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap... |
Does Knockout of RALB in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | RALB | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: RALB (RAS like proto-oncogene B)
Type: protein-coding
Summary: This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. [pr... |
Does Knockout of RNF128 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | RNF128 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: RNF128 (ring finger protein 128)
Type: protein-coding
Summary: The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this g... |
Does Knockout of ANAPC2 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | ANAPC2 | cell proliferation | Endometrial Cancer Cell Line | Gene: ANAPC2 (anaphase promoting complex subunit 2)
Type: protein-coding
Summary: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which... |
Does Knockout of FRMPD1 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | FRMPD1 | cell proliferation | Medulloblastoma Cell Line | Gene: FRMPD1 (FERM and PDZ domain containing 1)
Type: protein-coding
Summary: Involved in establishment of protein localization to membrane and regulation of G protein-coupled receptor signaling pathway. Located in plasma membrane. Part of protein-containing complex. Colocalizes with cell cortex. [provi... |
Does Knockout of SLC18B1 in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 734 | Knockout | SLC18B1 | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: SLC18B1 (solute carrier family 18 member B1)
Type: protein-coding
Summary: This gene encodes a protein, which has high sequence similarity to rat, xenopus and zebrafish proteins. The protein function is unknown. [provided by RefSeq, Jul 2008].
Gene Ontology: BP: polyamine transmembrane tr... |
Does Knockout of PET117 in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | PET117 | cell proliferation | Colorectal Cancer Cell Line | Gene: PET117 (PET117 cytochrome c oxidase chaperone)
Type: protein-coding
Summary: Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. Implicated in cytochrome-c oxidase deficiency disease. [provided by Alliance of Genome Resources, Apr 2022]
Gene ... |
Does Activation of SERPINI2 in Hepatoma Cell Line causally result in response to virus? | 0 | 1,210 | Activation | SERPINI2 | response to virus | Hepatoma Cell Line | Gene: SERPINI2 (serpin family I member 2)
Type: protein-coding
Summary: The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, mali... |
Does Knockout of DENND2D in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,032 | Knockout | DENND2D | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: DENND2D (DENN domain containing 2D)
Type: protein-coding
Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: g... |
Does Knockout of SFRP2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,658 | Knockout | SFRP2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: SFRP2 (secreted frizzled related protein 2)
Type: protein-coding
Summary: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene ... |
Does Activation of KCNK9 in Hepatoma Cell Line causally result in response to virus? | 1 | 1,210 | Activation | KCNK9 | response to virus | Hepatoma Cell Line | Gene: KCNK9 (potassium two pore domain channel subfamily K member 9)
Type: protein-coding
Summary: This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have... |
Does Knockout of SCTR in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | SCTR | cell proliferation | Mammary Gland Tumor Cell Line | Gene: SCTR (secretin receptor)
Type: protein-coding
Summary: The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secret... |
Does Knockout of WDR81 in Hepatoma Cell Line causally result in response to virus? | 1 | 2,437 | Knockout | WDR81 | response to virus | Hepatoma Cell Line | Gene: WDR81 (WD repeat domain 81)
Type: protein-coding
Summary: This gene encodes a multi-domain transmembrane protein which is predominantly expressed in the brain and is thought to play a role in endolysosomal trafficking. Mutations in this gene are associated with an autosomal recessive form of a syn... |
Does Knockout of CAMK2B in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | CAMK2B | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: CAMK2B (calcium/calmodulin dependent protein kinase II beta)
Type: protein-coding
Summary: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity ... |
Does Knockout of ZBTB14 in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | ZBTB14 | cell proliferation | Renal Cancer Cell Line | Gene: ZBTB14 (zinc finger and BTB domain containing 14)
Type: protein-coding
Summary: Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in negative regulation of transcription, DNA-templated. Located in aggresome; cytosol; and nuclear lu... |
Does Knockout of KCNC1 in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | KCNC1 | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: KCNC1 (potassium voltage-gated channel subfamily C member 1)
Type: protein-coding
Summary: This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two tra... |
Does Knockout of OR5C1 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | OR5C1 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: OR5C1 (olfactory receptor family 5 subfamily C member 1)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protei... |
Does Knockout of TAS2R16 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | TAS2R16 | cell proliferation | Colonic Cancer Cell Line | Gene: TAS2R16 (taste 2 receptor member 16)
Type: protein-coding
Summary: This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate ep... |
Does Knockout of DDA1 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 1 | 2,368 | Knockout | DDA1 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: DDA1 (DET1 and DDB1 associated 1)
Type: protein-coding
Summary: Involved in protein polyubiquitination. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: positive regulation of proteasomal ubiquitin-dependent protein cat... |
Does Knockout of PLA2G7 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,119 | Knockout | PLA2G7 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: PLA2G7 (phospholipase A2 group VII)
Type: protein-coding
Summary: The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase def... |
Does Knockout of NOC4L in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | NOC4L | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: NOC4L (nucleolar complex associated 4 homolog)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: rRNA processing, ribosome b... |
Does Knockout of DOC2A in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | DOC2A | cell proliferation | Gastric Cancer Cell Line | Gene: DOC2A (double C2 domain alpha)
Type: protein-coding
Summary: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrela... |
Does Knockout of SPCS2 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | SPCS2 | cell proliferation | Colorectal Cancer Cell Line | Gene: SPCS2 (signal peptidase complex subunit 2)
Type: protein-coding
Summary: Predicted to enable peptidase activity. Predicted to be involved in protein targeting to ER and signal peptide processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase co... |
Does Knockout of NUP62 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | NUP62 | cell proliferation | Gastric Cancer Cell Line | Gene: NUP62 (nucleoporin 62)
Type: protein-coding
Summary: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore... |
Does Knockout of PALB2 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 1 | 1,996 | Knockout | PALB2 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: PALB2 (partner and localizer of BRCA2)
Type: protein-coding
Summary: This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localizatio... |
Does Knockout of NAPA in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 1,813 | Knockout | NAPA | cell proliferation | Medulloblastoma Cell Line | Gene: NAPA (NSF attachment protein alpha)
Type: protein-coding
Summary: This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded prot... |
Does Knockout of DMAP1 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | DMAP1 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: DMAP1 (DNA methyltransferase 1 associated protein 1)
Type: protein-coding
Summary: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci t... |
Does Knockout of MID2 in Astrocytoma Cell Line causally result in cell proliferation? | 0 | 904 | Knockout | MID2 | cell proliferation | Astrocytoma Cell Line | Gene: MID2 (midline 2)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structur... |
Does Knockout of PSMA1 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | PSMA1 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: PSMA1 (proteasome 20S subunit alpha 1)
Type: protein-coding
Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 ri... |
Does Knockout of FAM171B in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | FAM171B | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: FAM171B (family with sequence similarity 171 member B)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: membrane, synapse
Pathways:
UniProt: Q6P995
Entrez ID: 16... |
Does Knockout of HMGB1 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | HMGB1 | cell proliferation | Medulloblastoma Cell Line | Gene: HMGB1 (high mobility group box 1)
Type: protein-coding
Summary: This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in se... |
Does Knockout of OR10G2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,459 | Knockout | OR10G2 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: OR10G2 (olfactory receptor family 10 subfamily G member 2)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of MINDY2 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 0 | 1,978 | Knockout | MINDY2 | response to chemicals | Monocytic Leukemia Cell Line | Gene: MINDY2 (MINDY lysine 48 deubiquitinase 2)
Type: protein-coding
Summary: Enables cysteine-type peptidase activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in protein K48-linked deubiquitination. Located in nucleoplasm. [provided by Alliance of Geno... |
Does Knockout of ADAM10 in Cancer Cell Line causally result in cell proliferation? | 0 | 948 | Knockout | ADAM10 | cell proliferation | Cancer Cell Line | Gene: ADAM10 (ADAM metallopeptidase domain 10)
Type: protein-coding
Summary: Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E... |
Does Knockout of SCN11A in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | SCN11A | cell proliferation | Renal Cancer Cell Line | Gene: SCN11A (sodium voltage-gated channel alpha subunit 11)
Type: protein-coding
Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generat... |
Does Knockout of TSACC in Glioblastoma Cell Line causally result in response to chemicals? | 1 | 2,344 | Knockout | TSACC | response to chemicals | Glioblastoma Cell Line | Gene: TSACC (TSSK6 activating cochaperone)
Type: protein-coding
Summary: Enables chaperone binding activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: protein binding, protein-folding chaperone binding; CC: cytoplasm
Pa... |
Does Knockout of RPL15 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | RPL15 | cell proliferation | Medulloblastoma Cell Line | Gene: RPL15 (ribosomal protein L15)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene enc... |
Does Knockout of NXF5 in Glioma Cell Line causally result in protein/peptide accumulation? | 0 | 589 | Knockout | NXF5 | protein/peptide accumulation | Glioma Cell Line | Gene: NXF5 (nuclear RNA export factor 5)
Type: pseudo
Summary: This gene is one member of a family of nuclear RNA export factor genes. Most transcript variants are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. [provided by RefSeq, Sep 2022].
Gene Ontology: B... |
Does Knockout of ZNF586 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | ZNF586 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: ZNF586 (zinc finger protein 586)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RN... |
Does Knockout of ATP6V1A in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | ATP6V1A | cell proliferation | Cancer Cell Line | Gene: ATP6V1A (ATPase H+ transporting V1 subunit A)
Type: protein-coding
Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intrac... |
Does Knockout of RSPH14 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | RSPH14 | cell proliferation | Cancer Cell Line | Gene: RSPH14 (radial spoke head 14 homolog)
Type: protein-coding
Summary: This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations i... |
Does Knockout of OR9Q1 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | OR9Q1 | cell proliferation | Glioblastoma Cell Line | Gene: OR9Q1 (olfactory receptor family 9 subfamily Q member 1)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protei... |
Does Knockout of CTBP2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | CTBP2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: CTBP2 (C-terminal binding protein 2)
Type: protein-coding
Summary: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins co... |
Does Knockout of CHAF1A in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | CHAF1A | cell proliferation | Glioblastoma Cell Line | Gene: CHAF1A (chromatin assembly factor 1 subunit A)
Type: protein-coding
Summary: Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7... |
Does Knockout of GTF3C1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 149 | Knockout | GTF3C1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: GTF3C1 (general transcription factor IIIC subunit 1)
Type: protein-coding
Summary: Predicted to contribute to DNA binding activity. Predicted to be involved in 5S class rRNA transcription by RNA polymerase III and transcription initiation from RNA polymerase III promoter. Located in nucleolus and ... |
Does Knockout of RPL39L in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | RPL39L | cell proliferation | Monocytic Leukemia Cell Line | Gene: RPL39L (ribosomal protein L39 like)
Type: protein-coding
Summary: This gene encodes a protein sharing high sequence similarity with ribosomal protein L39. Although the name of this gene has been referred to as 'ribosomal protein L39' in the public databases, its official name is 'ribosomal protein... |
Does Knockout of CASP7 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | CASP7 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: CASP7 (caspase 7)
Type: protein-coding
Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic proce... |
Does Knockout of TUBA1B in Ovarian Cancer Cell Line causally result in cell proliferation? | 1 | 699 | Knockout | TUBA1B | cell proliferation | Ovarian Cancer Cell Line | Gene: TUBA1B (tubulin alpha 1b)
Type: protein-coding
Summary: Enables double-stranded RNA binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within cellular response to ... |
Does Knockout of CTCF in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | CTCF | cell proliferation | Endometrial Cancer Cell Line | Gene: CTCF (CCCTC-binding factor)
Type: protein-coding
Summary: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind di... |
Does Knockout of RNF103 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,658 | Knockout | RNF103 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: RNF103 (ring finger protein 103)
Type: protein-coding
Summary: The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expressio... |
Does Activation of PPIAL4G in Hepatoma Cell Line causally result in response to virus? | 0 | 1,210 | Activation | PPIAL4G | response to virus | Hepatoma Cell Line | Gene: PPIAL4G (peptidylprolyl isomerase A like 4G)
Type: protein-coding
Summary: Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm... |
Does Knockout of PROSER3 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 69 | Knockout | PROSER3 | cell proliferation | Monocytic Leukemia Cell Line | Gene: PROSER3 (proline and serine rich 3)
Type: protein-coding
Summary: Located in centrosome. [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontology: CC: centrosome, cytoplasm, cytoskeleton
Pathways:
UniProt: Q2NL68
Entrez ID: 148137 |
Does Knockout of FAF2 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | FAF2 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: FAF2 (Fas associated factor family member 2)
Type: protein-coding
Summary: The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed... |
Does Knockout of ZNF578 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | ZNF578 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: ZNF578 (zinc finger protein 578)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RN... |
Does Knockout of CENPE in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | CENPE | cell proliferation | Glioblastoma Cell Line | Gene: CENPE (centromere protein E)
Type: protein-coding
Summary: Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromer... |
Does Knockout of NUP160 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | NUP160 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: NUP160 (nucleoporin 160)
Type: protein-coding
Summary: NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]
Gene Ontology: BP: mRNA export from nucleus, mRNA transport, nephron development, nucle... |
Does Knockout of LAMTOR4 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | LAMTOR4 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: LAMTOR4 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 4)
Type: protein-coding
Summary: Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cellular response to amino acid stimulus; positive regulation of TO... |
Does Knockout of FDPS in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | FDPS | cell proliferation | Cancer Cell Line | Gene: FDPS (farnesyl diphosphate synthase)
Type: protein-coding
Summary: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key i... |
Does Knockout of SREK1 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | SREK1 | cell proliferation | Gastric Cancer Cell Line | Gene: SREK1 (splicing regulatory glutamic acid and lysine rich protein 1)
Type: protein-coding
Summary: This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate s... |
Does Knockout of OR6M1 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | OR6M1 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: OR6M1 (olfactory receptor family 6 subfamily M member 1)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protei... |
Does Knockout of SLC4A5 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | SLC4A5 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: SLC4A5 (solute carrier family 4 member 5)
Type: protein-coding
Summary: This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural ... |
Does Knockout of NEO1 in Astrocytoma Cell Line causally result in cell proliferation? | 0 | 904 | Knockout | NEO1 | cell proliferation | Astrocytoma Cell Line | Gene: NEO1 (neogenin 1)
Type: protein-coding
Summary: This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal intern... |
Does Knockout of SPTLC1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 427 | Knockout | SPTLC1 | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: SPTLC1 (serine palmitoyltransferase long chain base subunit 1)
Type: protein-coding
Summary: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransf... |
Does Knockout of LAGE3 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | LAGE3 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: LAGE3 (L antigen family member 3)
Type: protein-coding
Summary: This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activa... |
Does Knockout of CLK2 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | CLK2 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: CLK2 (CDC like kinase 2)
Type: protein-coding
Summary: This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influe... |
Does Knockout of LTF in Melanoma Cell Line causally result in cell proliferation? | 0 | 527 | Knockout | LTF | cell proliferation | Melanoma Cell Line | Gene: LTF (lactotransferrin)
Type: protein-coding
Summary: This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it... |
Does Knockout of GABRG1 in Colorectal Cancer Cell Line causally result in response to chemicals? | 0 | 1,414 | Knockout | GABRG1 | response to chemicals | Colorectal Cancer Cell Line | Gene: GABRG1 (gamma-aminobutyric acid type A receptor subunit gamma1)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodia... |
Does Knockout of NTNG1 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | NTNG1 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: NTNG1 (netrin G1)
Type: protein-coding
Summary: This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with ... |
Does Knockout of GLMN in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | GLMN | cell proliferation | Monocytic Leukemia Cell Line | Gene: GLMN (glomulin, FKBP associated protein)
Type: protein-coding
Summary: This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenou... |
Does Knockout of SIRT3 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | SIRT3 | cell proliferation | Colonic Cancer Cell Line | Gene: SIRT3 (sirtuin 3)
Type: protein-coding
Summary: SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and preve... |
Does Knockout of INTS5 in Colonic Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 1,736 | Knockout | INTS5 | response to chemicals | Colonic Adenocarcinoma Cell Line | Gene: INTS5 (integrator complex subunit 5)
Type: protein-coding
Summary: The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processi... |
Does Knockout of DNAL4 in Non-Small Cell Lung Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 1,391 | Knockout | DNAL4 | response to chemicals | Non-Small Cell Lung Adenocarcinoma Cell Line | Gene: DNAL4 (dynein axonemal light chain 4)
Type: protein-coding
Summary: This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encod... |
Does Knockout of STMN1 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,430 | Knockout | STMN1 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: STMN1 (stathmin 1)
Type: protein-coding
Summary: This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the reg... |
Does Knockout of UNC5C in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | UNC5C | cell proliferation | Renal Cancer Cell Line | Gene: UNC5C (unc-5 netrin receptor C)
Type: protein-coding
Summary: This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some ce... |
Does Knockout of RELB in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | RELB | cell proliferation | Renal Cancer Cell Line | Gene: RELB (RELB proto-oncogene, NF-kB subunit)
Type: protein-coding
Summary: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located ... |
Does Knockout of TTC34 in Breast Cancer Cell Line causally result in cell proliferation? | 0 | 235 | Knockout | TTC34 | cell proliferation | Breast Cancer Cell Line | Gene: TTC34 (tetratricopeptide repeat domain 34)
Type: protein-coding
Summary: tetratricopeptide repeat domain 34
Gene Ontology:
Pathways:
UniProt: A8MYJ7
Entrez ID: 100287898 |
Does Knockout of AURKB in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | AURKB | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: AURKB (aurora kinase B)
Type: protein-coding
Summary: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and... |
Does Knockout of GPX4 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | GPX4 | cell proliferation | Glioblastoma Cell Line | Gene: GPX4 (glutathione peroxidase 4)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative da... |
Does Knockout of ANP32E in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,329 | Knockout | ANP32E | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: ANP32E (acidic nuclear phosphoprotein 32 family member E)
Type: protein-coding
Summary: Enables histone binding activity. Involved in histone exchange. Located in nucleus. Part of Swr1 complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: chromatin organization,... |
Does Knockout of SNCAIP in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 427 | Knockout | SNCAIP | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: SNCAIP (synuclein alpha interacting protein)
Type: protein-coding
Summary: This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in n... |
Does Knockout of TNS4 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | TNS4 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: TNS4 (tensin 4)
Type: protein-coding
Summary: Predicted to enable actin binding activity. Involved in protein localization. Located in focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: actin binding, protein binding; CC: anchoring junction, cytoplasm,... |
Does Knockout of XRN2 in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | XRN2 | cell proliferation | Cancer Cell Line | Gene: XRN2 (5'-3' exoribonuclease 2)
Type: protein-coding
Summary: This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
... |
Does Knockout of STK3 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 287 | Knockout | STK3 | cell proliferation | Endometrial Cancer Cell Line | Gene: STK3 (serine/threonine kinase 3)
Type: protein-coding
Summary: This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal porti... |
Does Knockout of NOTO in Neuroblastoma Cell Line causally result in cell proliferation? | 0 | 824 | Knockout | NOTO | cell proliferation | Neuroblastoma Cell Line | Gene: NOTO (notochord homeobox)
Type: protein-coding
Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in central nervous system development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or with... |
Does Knockout of RSRC1 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | RSRC1 | cell proliferation | Medulloblastoma Cell Line | Gene: RSRC1 (arginine and serine rich coiled-coil 1)
Type: protein-coding
Summary: This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseu... |
Does Knockout of RNF130 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | RNF130 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: RNF130 (ring finger protein 130)
Type: protein-coding
Summary: The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found... |
Does Knockout of MAN1C1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | MAN1C1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: MAN1C1 (mannosidase alpha class 1C member 1)
Type: protein-coding
Summary: Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
G... |
Does Knockout of EIF3M in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | EIF3M | cell proliferation | Gastric Cancer Cell Line | Gene: EIF3M (eukaryotic translation initiation factor 3 subunit M)
Type: protein-coding
Summary: This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell ... |
Does Knockout of NCMAP in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,430 | Knockout | NCMAP | response to virus | Cervical Adenocarcinoma Cell Line | Gene: NCMAP (non-compact myelin associated protein)
Type: protein-coding
Summary: Predicted to be a structural constituent of myelin sheath. Predicted to be involved in peripheral nervous system myelin formation and positive regulation of myelination. Predicted to be integral component of plasma membran... |
Does Knockout of PRMT5 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | PRMT5 | cell proliferation | Gastric Cancer Cell Line | Gene: PRMT5 (protein arginine methyltransferase 5)
Type: protein-coding
Summary: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elo... |
Does Knockout of TMSB4Y in Ovarian Cancer Cell Line causally result in cell proliferation? | 1 | 699 | Knockout | TMSB4Y | cell proliferation | Ovarian Cancer Cell Line | Gene: TMSB4Y (thymosin beta 4 Y-linked)
Type: protein-coding
Summary: This gene lies within the male specific region of chromosome Y. Its homolog on chromosome X escapes X inactivation and encodes an actin sequestering protein. [provided by RefSeq, Jul 2008].
Gene Ontology: BP: actin filament o... |
Does Knockout of NAGK in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | NAGK | cell proliferation | T-lymphoma cell line | Gene: NAGK (N-acetylglucosamine kinase)
Type: protein-coding
Summary: This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino s... |
Does Knockout of LRRC14 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 1 | 1,397 | Knockout | LRRC14 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: LRRC14 (leucine rich repeat containing 14)
Type: protein-coding
Summary: This gene encodes a leucine-rich repeat-containing protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012].
Gene Ontology: BP: negative regulation of NF-kappaB transcriptio... |
Does Knockout of MMS19 in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | MMS19 | cell proliferation | Renal Cancer Cell Line | Gene: MMS19 (MMS19 cytosolic iron-sulfur assembly component)
Type: protein-coding
Summary: Enables estrogen receptor binding activity and transcription coactivator activity. Involved in several processes, including iron-sulfur cluster assembly; positive regulation of nucleobase-containing compound metab... |
Does Knockout of ZSCAN12 in Colorectal Cancer Cell Line causally result in response to chemicals? | 0 | 1,414 | Knockout | ZSCAN12 | response to chemicals | Colorectal Cancer Cell Line | Gene: ZSCAN12 (zinc finger and SCAN domain containing 12)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of ... |
Does Knockout of HAUS5 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | HAUS5 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: HAUS5 (HAUS augmin like complex subunit 5)
Type: protein-coding
Summary: HAUS5 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin compl... |
Does Knockout of TMSB10 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 951 | Knockout | TMSB10 | cell proliferation | Colonic Cancer Cell Line | Gene: TMSB10 (thymosin beta 10)
Type: protein-coding
Summary: Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration and sequestering of actin monomers. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. [provided by Allian... |
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