prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of IL1RAPL2 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | IL1RAPL2 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: IL1RAPL2 (interleukin 1 receptor accessory protein like 2)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accesso... |
Does Knockout of TAF1D in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | TAF1D | cell proliferation | Medulloblastoma Cell Line | Gene: TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D)
Type: protein-coding
Summary: TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription ... |
Does Knockout of RBMXL1 in T-lymphoma cell line causally result in cell proliferation? | 1 | 478 | Knockout | RBMXL1 | cell proliferation | T-lymphoma cell line | Gene: RBMXL1 (RBMX like 1)
Type: protein-coding
Summary: This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific ... |
Does Knockout of MRGBP in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | MRGBP | cell proliferation | Monocytic Leukemia Cell Line | Gene: MRGBP (MRG domain binding protein)
Type: protein-coding
Summary: Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: chromatin organization, po... |
Does Knockout of SCG3 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | SCG3 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: SCG3 (secretogranin III)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper pr... |
Does Knockout of BCL6 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 387 | Knockout | BCL6 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: BCL6 (BCL6 transcription repressor)
Type: protein-coding
Summary: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of S... |
Does Knockout of FCF1 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,114 | Knockout | FCF1 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: FCF1 (FCF1 rRNA-processing protein)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in rRNA processing. Predicted to act upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic... |
Does Knockout of ARSF in Colorectal Cancer Cell Line causally result in response to chemicals? | 0 | 1,414 | Knockout | ARSF | response to chemicals | Colorectal Cancer Cell Line | Gene: ARSF (arylsulfatase F)
Type: protein-coding
Summary: This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are deriv... |
Does Knockout of RAB10 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | RAB10 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: RAB10 (RAB10, member RAS oncogene family)
Type: protein-coding
Summary: RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[sup... |
Does Knockout of SPINK5 in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | SPINK5 | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: SPINK5 (serine peptidase inhibitor Kazal type 5)
Type: protein-coding
Summary: This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit un... |
Does Knockout of ZNF736 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 305 | Knockout | ZNF736 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: ZNF736 (zinc finger protein 736)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-... |
Does Knockout of MRPL32 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | MRPL32 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: MRPL32 (mitochondrial ribosomal protein L32)
Type: protein-coding
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.... |
Does Knockout of CEP44 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | CEP44 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: CEP44 (centrosomal protein 44)
Type: protein-coding
Summary: Enables microtubule binding activity. Involved in centriole replication and centriole-centriole cohesion. Located in centriole; centrosome; and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP... |
Does Knockout of CCDC186 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 427 | Knockout | CCDC186 | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: CCDC186 (coiled-coil domain containing 186)
Type: protein-coding
Summary: Predicted to enable small GTPase binding activity. Predicted to be involved in vesicle cytoskeletal trafficking. Predicted to act upstream of or within insulin secretion involved in cellular response to glucose stimulus and ... |
Does Knockout of MRPL33 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | MRPL33 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: MRPL33 (mitochondrial ribosomal protein L33)
Type: protein-coding
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.... |
Does Knockout of C3orf38 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | C3orf38 | cell proliferation | Endometrial Cancer Cell Line | Gene: C3orf38 (chromosome 3 open reading frame 38)
Type: protein-coding
Summary: Involved in positive regulation of apoptotic process. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: apoptotic process, positive regulation of apoptotic process
... |
Does Knockout of FCAMR in Cancer Cell Line causally result in cell proliferation? | 0 | 1,308 | Knockout | FCAMR | cell proliferation | Cancer Cell Line | Gene: FCAMR (Fc alpha and mu receptor)
Type: protein-coding
Summary: Predicted to enable IgA binding activity; IgM binding activity; and transmembrane signaling receptor activity. Predicted to be involved in adaptive immune response. Predicted to be integral component of membrane. Predicted to be active... |
Does Knockout of MAT1A in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | MAT1A | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: MAT1A (methionine adenosyltransferase 1A)
Type: protein-coding
Summary: This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionin... |
Does Knockout of VMP1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | VMP1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: VMP1 (vacuole membrane protein 1)
Type: protein-coding
Summary: This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This g... |
Does Knockout of ZMYND8 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | ZMYND8 | cell proliferation | Monocytic Leukemia Cell Line | Gene: ZMYND8 (zinc finger MYND-type containing 8)
Type: protein-coding
Summary: The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell ... |
Does Knockout of SPC24 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | SPC24 | cell proliferation | Gastric Cancer Cell Line | Gene: SPC24 (SPC24 component of NDC80 kinetochore complex)
Type: protein-coding
Summary: Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. Part of Ndc80 complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: attachment of spindle microtub... |
Does Knockout of STAT3 in Diffuse Large B-cell Lymphoma Cell causally result in response to chemicals? | 0 | 2,222 | Knockout | STAT3 | response to chemicals | Diffuse Large B-cell Lymphoma Cell | Gene: STAT3 (signal transducer and activator of transcription 3)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form ho... |
Does Knockout of WNT7A in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 865 | Knockout | WNT7A | cell proliferation | Colonic Cancer Cell Line | Gene: WNT7A (Wnt family member 7A)
Type: protein-coding
Summary: This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regula... |
Does Knockout of GCDH in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | GCDH | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: GCDH (glutaryl-CoA dehydrogenase)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptop... |
Does Knockout of NXF1 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | NXF1 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: NXF1 (nuclear RNA export factor 1)
Type: protein-coding
Summary: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-li... |
Does Knockout of RIF1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | RIF1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: RIF1 (replication timing regulatory factor 1)
Type: protein-coding
Summary: This gene encodes a protein that shares homology with the yeast teleomere binding protein, Rap1 interacting factor 1. This protein localizes to aberrant telomeres may be involved in DNA repair. Alternate splicing results i... |
Does Knockout of SRSF1 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | SRSF1 | cell proliferation | Glioblastoma Cell Line | Gene: SRSF1 (serine and arginine rich splicing factor 1)
Type: protein-coding
Summary: This gene encodes a member of the arginine/serine-rich splicing factor protein family. The encoded protein can either activate or repress splicing, depending on its phosphorylation state and its interaction partners. ... |
Does Knockout of TUSC1 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | TUSC1 | cell proliferation | Glioblastoma Cell Line | Gene: TUSC1 (tumor suppressor candidate 1)
Type: protein-coding
Summary: This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell l... |
Does Knockout of ECD in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | ECD | cell proliferation | Multiple Myeloma Cell Line | Gene: ECD (ecdysoneless cell cycle regulator)
Type: protein-coding
Summary: Enables histone acetyltransferase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene On... |
Does Knockout of CEP55 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 149 | Knockout | CEP55 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: CEP55 (centrosomal protein 55)
Type: protein-coding
Summary: Enables identical protein binding activity. Involved in cranial skeletal system development; establishment of protein localization; and midbody abscission. Acts upstream of or within mitotic cytokinesis. Located in Flemming body; centrio... |
Does Knockout of RPAP2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | RPAP2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RPAP2 (RNA polymerase II associated protein 2)
Type: protein-coding
Summary: Enables RNA polymerase II CTD heptapeptide repeat phosphatase activity. Involved in dephosphorylation of RNA polymerase II C-terminal domain and snRNA transcription. Located in cytosol and nucleolus. Part of RNA polymeras... |
Does Knockout of TRA2B in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | TRA2B | cell proliferation | Multiple Myeloma Cell Line | Gene: TRA2B (transformer 2 beta homolog)
Type: protein-coding
Summary: This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcri... |
Does Knockout of TRAPPC13 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | TRAPPC13 | cell proliferation | Gastric Cancer Cell Line | Gene: TRAPPC13 (trafficking protein particle complex subunit 13)
Type: protein-coding
Summary: Predicted to be located in cytosol. Predicted to be part of TRAPPIII protein complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-med... |
Does Knockout of ZDHHC6 in Colonic Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,736 | Knockout | ZDHHC6 | response to chemicals | Colonic Adenocarcinoma Cell Line | Gene: ZDHHC6 (zDHHC palmitoyltransferase 6)
Type: protein-coding
Summary: Enables palmitoyltransferase activity. Involved in positive regulation of mitochondrial fusion and protein palmitoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontolo... |
Does Knockout of DHPS in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | DHPS | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: DHPS (deoxyhypusine synthase)
Type: protein-coding
Summary: This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes t... |
Does Knockout of NIP7 in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | NIP7 | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: NIP7 (nucleolar pre-rRNA processing protein NIP7)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:... |
Does Knockout of FOXD4 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | FOXD4 | cell proliferation | Gastric Cancer Cell Line | Gene: FOXD4 (forkhead box D4)
Type: protein-coding
Summary: This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expressio... |
Does Activation of TXLNG in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | TXLNG | protein/peptide accumulation | T cell | Gene: TXLNG (taxilin gamma)
Type: protein-coding
Summary: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipo... |
Does Knockout of ATP6V1D in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | ATP6V1D | cell proliferation | Breast Cancer Cell Line | Gene: ATP6V1D (ATPase H+ transporting V1 subunit D)
Type: protein-coding
Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intrac... |
Does Knockout of COPS3 in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | COPS3 | cell proliferation | Multiple Myeloma Cell Line | Gene: COPS3 (COP9 signalosome subunit 3)
Type: protein-coding
Summary: The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylat... |
Does Knockout of OIT3 in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | OIT3 | cell proliferation | Renal Cancer Cell Line | Gene: OIT3 (oncoprotein induced transcript 3)
Type: protein-coding
Summary: This gene was identified due to its downregulation in hepatocarcinomas. The encoded protein may be involved in liver development and function. [provided by RefSeq, Sep 2016].
Gene Ontology: MF: calcium ion binding, prot... |
Does Knockout of SMG6 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | SMG6 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: SMG6 (SMG6 nonsense mediated mRNA decay factor)
Type: protein-coding
Summary: This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD... |
Does Knockout of RPN2 in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | RPN2 | cell proliferation | Renal Cancer Cell Line | Gene: RPN2 (ribophorin II)
Type: protein-coding
Summary: This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the... |
Does Knockout of NYNRIN in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 387 | Knockout | NYNRIN | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: NYNRIN (NYN domain and retroviral integrase containing)
Type: protein-coding
Summary: Predicted to enable endoribonuclease activity and mRNA binding activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic. Predicted to be integral component of membrane. Predicted ... |
Does Knockout of THOC3 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | THOC3 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: THOC3 (THO complex subunit 3)
Type: protein-coding
Summary: This gene encodes a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export compl... |
Does Knockout of COASY in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | COASY | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: COASY (Coenzyme A synthase)
Type: protein-coding
Summary: Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved ... |
Does Knockout of KRTAP1-4 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 865 | Knockout | KRTAP1-4 | cell proliferation | Colonic Cancer Cell Line | Gene: KRTAP1-4 (keratin associated protein 1-4)
Type: protein-coding
Summary: The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs), which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking ... |
Does Knockout of NASP in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | NASP | cell proliferation | Colonic Cancer Cell Line | Gene: NASP (nuclear autoantigenic sperm protein)
Type: protein-coding
Summary: This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in ... |
Does Knockout of TTI2 in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | TTI2 | cell proliferation | Cancer Cell Line | Gene: TTI2 (TELO2 interacting protein 2)
Type: protein-coding
Summary: This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1. The TTT complex is involved in... |
Does Knockout of LHX4 in Diffuse Large B-cell Lymphoma Cell causally result in response to chemicals? | 0 | 2,222 | Knockout | LHX4 | response to chemicals | Diffuse Large B-cell Lymphoma Cell | Gene: LHX4 (LIM homeobox 4)
Type: protein-coding
Summary: This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituit... |
Does Knockout of RASSF1 in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | RASSF1 | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: RASSF1 (Ras association domain family member 1)
Type: protein-coding
Summary: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of... |
Does Knockout of ETFDH in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | ETFDH | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: ETFDH (electron transfer flavoprotein dehydrogenase)
Type: protein-coding
Summary: This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mut... |
Does Knockout of EBNA1BP2 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | EBNA1BP2 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: EBNA1BP2 (EBNA1 binding protein 2)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in rRNA processing and ribosomal large subunit biogenesis. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: r... |
Does Knockout of CFDP1 in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | CFDP1 | cell proliferation | Bladder Carcinoma | Gene: CFDP1 (craniofacial development protein 1)
Type: protein-coding
Summary: Predicted to act upstream of or within several processes, including cell adhesion; negative regulation of fibroblast apoptotic process; and regulation of cell shape. Predicted to be located in kinetochore. [provided by Allian... |
Does Activation of NXT2 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | NXT2 | protein/peptide accumulation | T cell | Gene: NXT2 (nuclear transport factor 2 like export factor 2)
Type: protein-coding
Summary: The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus... |
Does Knockout of SMDT1 in Lung Cancer Cell Line causally result in response to virus? | 0 | 1,433 | Knockout | SMDT1 | response to virus | Lung Cancer Cell Line | Gene: SMDT1 (single-pass membrane protein with aspartate rich tail 1)
Type: protein-coding
Summary: This gene encodes a core regulatory component of a calcium channel in the mitochondrial inner membrane. [provided by RefSeq, Apr 2017].
Gene Ontology: BP: calcium import into the mitochondrion, c... |
Does Knockout of AHR in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | AHR | cell proliferation | Medulloblastoma Cell Line | Gene: AHR (aryl hydrocarbon receptor)
Type: protein-coding
Summary: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabol... |
Does Knockout of FN1 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,430 | Knockout | FN1 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: FN1 (fibronectin 1)
Type: protein-coding
Summary: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the m... |
Does Knockout of RPL35 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | RPL35 | cell proliferation | Medulloblastoma Cell Line | Gene: RPL35 (ribosomal protein L35)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of KIF3B in Multiple Myeloma Cell Line causally result in cell proliferation? | 0 | 816 | Knockout | KIF3B | cell proliferation | Multiple Myeloma Cell Line | Gene: KIF3B (kinesin family member 3B)
Type: protein-coding
Summary: The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 ... |
Does Knockout of POLR1E in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 865 | Knockout | POLR1E | cell proliferation | Colonic Cancer Cell Line | Gene: POLR1E (RNA polymerase I subunit E)
Type: protein-coding
Summary: Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and RNA polymerase I general transcription initiation factor binding activity. Involved in nucleolar large rRNA transcription by RNA polymerase I.... |
Does Knockout of ZBTB43 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 149 | Knockout | ZBTB43 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: ZBTB43 (zinc finger and BTB domain containing 43)
Type: protein-coding
Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provi... |
Does Knockout of LIMK1 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 387 | Knockout | LIMK1 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: LIMK1 (LIM domain kinase 1)
Type: protein-coding
Summary: There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to D... |
Does Knockout of SARAF in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | SARAF | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: SARAF (store-operated calcium entry associated regulatory factor)
Type: protein-coding
Summary: Involved in regulation of store-operated calcium entry. Located in endoplasmic reticulum and endoplasmic reticulum-plasma membrane contact site. Is integral component of endoplasmic reticulum membrane. ... |
Does Knockout of ING4 in Lung Cancer Cell Line causally result in response to virus? | 0 | 1,433 | Knockout | ING4 | response to virus | Lung Cancer Cell Line | Gene: ING4 (inhibitor of growth family member 4)
Type: protein-coding
Summary: This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl trans... |
Does Knockout of POLD2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | POLD2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: POLD2 (DNA polymerase delta 2, accessory subunit)
Type: protein-coding
Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The enco... |
Does Knockout of CHTOP in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | CHTOP | cell proliferation | Endometrial Cancer Cell Line | Gene: CHTOP (chromatin target of PRMT1)
Type: protein-coding
Summary: This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-respon... |
Does Knockout of CXCR3 in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | CXCR3 | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: CXCR3 (C-X-C motif chemokine receptor 3)
Type: protein-coding
Summary: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducib... |
Does Knockout of TMCO1 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | TMCO1 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: TMCO1 (transmembrane and coiled-coil domains 1)
Type: protein-coding
Summary: This locus encodes a transmembrane protein. Mutations at this locus have been associated with craniofacial dysmorphism, skeletal anomalies, and cognitive disability. Mutations at this locus have also been associated with... |
Does Knockout of POLR3A in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | POLR3A | cell proliferation | Colorectal Cancer Cell Line | Gene: POLR3A (RNA polymerase III subunit A)
Type: protein-coding
Summary: The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response. [provided by R... |
Does Knockout of ABT1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | ABT1 | cell proliferation | Endometrial Cancer Cell Line | Gene: ABT1 (activator of basal transcription 1)
Type: protein-coding
Summary: Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activa... |
Does Knockout of MCM2 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | MCM2 | cell proliferation | Colonic Cancer Cell Line | Gene: MCM2 (minichromosome maintenance complex component 2)
Type: protein-coding
Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed ... |
Does Knockout of KIF14 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | KIF14 | cell proliferation | Monocytic Leukemia Cell Line | Gene: KIF14 (kinesin family member 14)
Type: protein-coding
Summary: This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. I... |
Does Knockout of RPL5 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 815 | Knockout | RPL5 | cell proliferation | Colonic Cancer Cell Line | Gene: RPL5 (ribosomal protein L5)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encod... |
Does Knockout of NSMCE1 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | NSMCE1 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: NSMCE1 (NSE1 component of SMC5/6 complex)
Type: protein-coding
Summary: Enables protein dimerization activity and ubiquitin protein ligase activity. Involved in positive regulation of response to DNA damage stimulus. Located in nucleoplasm. Part of Smc5-Smc6 complex. [provided by Alliance of Genom... |
Does Knockout of RNF149 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 334 | Knockout | RNF149 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: RNF149 (ring finger protein 149)
Type: protein-coding
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of M... |
Does Knockout of CKAP5 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | CKAP5 | cell proliferation | Monocytic Leukemia Cell Line | Gene: CKAP5 (cytoskeleton associated protein 5)
Type: protein-coding
Summary: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding t... |
Does Knockout of CWC22 in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | CWC22 | cell proliferation | Multiple Myeloma Cell Line | Gene: CWC22 (CWC22 spliceosome associated protein)
Type: protein-coding
Summary: Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in cytosol and nuclear speck. Part of U2-type catalytic step 1 spliceosome; U2-type catalytic step 2 spliceosome; and U2-type precatalytic sp... |
Does Knockout of HMSD in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | HMSD | cell proliferation | Glioblastoma Cell Line | Gene: HMSD (histocompatibility minor serpin domain containing)
Type: protein-coding
Summary: This gene encodes a serpin-domain containing protein that may function as a serine protease inhibitor. This gene is primarily expressed in cells of myeloid lineage. A polymorphism in this gene may result in the ... |
Does Knockout of SLC12A7 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | SLC12A7 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: SLC12A7 (solute carrier family 12 member 7)
Type: protein-coding
Summary: Enables protein kinase binding activity. Predicted to be involved in several processes, including cell volume homeostasis; inorganic ion homeostasis; and inorganic ion transmembrane transport. Part of protein-containing comp... |
Does Knockout of NPLOC4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,459 | Knockout | NPLOC4 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Type: protein-coding
Summary: Predicted to enable ATPase binding activity; ubiquitin binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to K48-linked polyubiquitin modification-dependent protein binding activ... |
Does Knockout of TIMM13 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | TIMM13 | cell proliferation | Glioblastoma Cell Line | Gene: TIMM13 (translocase of inner mitochondrial membrane 13)
Type: protein-coding
Summary: This gene encodes a member of the evolutionarily conserved TIMM (translocase of inner mitochondrial membrane) family of proteins that function as chaperones in the import of proteins from the cytoplasm into the m... |
Does Knockout of TTK in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 1,813 | Knockout | TTK | cell proliferation | Medulloblastoma Cell Line | Gene: TTK (TTK protein kinase)
Type: protein-coding
Summary: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and i... |
Does Knockout of CDK7 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | CDK7 | cell proliferation | Monocytic Leukemia Cell Line | Gene: CDK7 (cyclin dependent kinase 7)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are... |
Does Knockout of ATP2C2 in Hepatoma Cell Line causally result in cell proliferation? | 0 | 1,206 | Knockout | ATP2C2 | cell proliferation | Hepatoma Cell Line | Gene: ATP2C2 (ATPase secretory pathway Ca2+ transporting 2)
Type: protein-coding
Summary: Enables P-type calcium transporter activity and P-type manganese transporter activity. Predicted to be involved in calcium ion transmembrane transport; cellular calcium ion homeostasis; and manganese ion transport.... |
Does Knockout of CCT3 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 906 | Knockout | CCT3 | cell proliferation | Glioblastoma Cell Line | Gene: CCT3 (chaperonin containing TCP1 subunit 3)
Type: protein-coding
Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, ea... |
Does Knockout of HAUS4 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | HAUS4 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: HAUS4 (HAUS augmin like complex subunit 4)
Type: protein-coding
Summary: This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome in... |
Does Knockout of URM1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | URM1 | cell proliferation | Melanoma Cell Line | Gene: URM1 (ubiquitin related modifier 1)
Type: protein-coding
Summary: Enables sulfur carrier activity. Involved in tRNA thio-modification and tRNA wobble uridine modification. Predicted to be located in cytosol. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of NMUR1 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 0 | 180 | Knockout | NMUR1 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: NMUR1 (neuromedin U receptor 1)
Type: protein-coding
Summary: Enables neuromedin U binding activity and neuromedin U receptor activity. Involved in several processes, including activation of phospholipase C activity; chloride transport; and second-messenger-mediated signaling. Is integral componen... |
Does Knockout of CDC20 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | CDC20 | cell proliferation | Monocytic Leukemia Cell Line | Gene: CDC20 (cell division cycle 20)
Type: protein-coding
Summary: CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separati... |
Does Knockout of RPS27A in Prostate Cancer Cell Line causally result in cell proliferation? | 1 | 843 | Knockout | RPS27A | cell proliferation | Prostate Cancer Cell Line | Gene: RPS27A (ribosomal protein S27a)
Type: protein-coding
Summary: Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fuse... |
Does Knockout of PRICKLE2 in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | PRICKLE2 | cell proliferation | Renal Cancer Cell Line | Gene: PRICKLE2 (prickle planar cell polarity protein 2)
Type: protein-coding
Summary: This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated wit... |
Does Knockout of RPS23 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 149 | Knockout | RPS23 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: RPS23 (ribosomal protein S23)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of ISY1 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | ISY1 | cell proliferation | Medulloblastoma Cell Line | Gene: ISY1 (ISY1 spliceosome associated protein)
Type: protein-coding
Summary: Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type catalytic step 1 spliceosome and catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Apr 2022]... |
Does Knockout of TBC1D25 in Prostate Cancer Cell Line causally result in cell proliferation? | 0 | 843 | Knockout | TBC1D25 | cell proliferation | Prostate Cancer Cell Line | Gene: TBC1D25 (TBC1 domain family member 25)
Type: protein-coding
Summary: This gene encodes a protein with a TBC domain and functions as a Rab GTPase activating protein. The encoded protein is involved in the fusion of autophagosomes with endosomes and lysosomes. This gene was previously known as ornit... |
Does Knockout of ANO1 in Bladder Carcinoma causally result in cell proliferation? | 0 | 489 | Knockout | ANO1 | cell proliferation | Bladder Carcinoma | Gene: ANO1 (anoctamin 1)
Type: protein-coding
Summary: Enables calcium activated cation channel activity; intracellular calcium activated chloride channel activity; and iodide transmembrane transporter activity. Involved in cation transport; inorganic anion transport; and positive regulation of insulin ... |
Does Knockout of TYMS in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | TYMS | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: TYMS (thymidylate synthetase)
Type: protein-coding
Summary: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for D... |
Does Knockout of RFT1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | RFT1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RFT1 (RFT1 glycolipid translocator homolog)
Type: protein-coding
Summary: This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation ... |
Does Knockout of RARS2 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | RARS2 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: RARS2 (arginyl-tRNA synthetase 2, mitochondrial)
Type: protein-coding
Summary: This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in... |
Does Knockout of IL15 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | IL15 | cell proliferation | Medulloblastoma Cell Line | Gene: IL15 (interleukin 15)
Type: protein-coding
Summary: The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.