prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of NSA2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | NSA2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: NSA2 (NSA2 ribosome biogenesis factor)
Type: protein-coding
Summary: This gene encodes a nucleolar protein involved in cell cycle regulation and proliferation. This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein... |
Does Knockout of ZDHHC19 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | ZDHHC19 | response to virus | Hepatoma Cell Line | Gene: ZDHHC19 (zDHHC palmitoyltransferase 19)
Type: protein-coding
Summary: Enables protein-cysteine S-palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in Golgi membrane; endoplasmic reticulum; and perinucleolar compartment. [provided by Alliance of Genome Resourc... |
Does Knockout of PADI1 in Bladder Carcinoma causally result in cell proliferation? | 0 | 489 | Knockout | PADI1 | cell proliferation | Bladder Carcinoma | Gene: PADI1 (peptidyl arginine deiminase 1)
Type: protein-coding
Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The f... |
Does Knockout of KRI1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | KRI1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: KRI1 (KRI1 homolog)
Type: protein-coding
Summary: This gene overlaps with the gene for cysteine endopeptidase AUT-like 4 in a head-to-tail orientation. [provided by RefSeq, Jul 2008].
Gene Ontology: CC: 90S preribosome, nucleolus
Pathways:
UniProt: Q8N9T8
Entrez... |
Does Knockout of TAF10 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 427 | Knockout | TAF10 | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: TAF10 (TATA-box binding protein associated factor 10)
Type: protein-coding
Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core prom... |
Does Knockout of DHODH in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | DHODH | cell proliferation | Monocytic Leukemia Cell Line | Gene: DHODH (dihydroorotate dehydrogenase (quinone))
Type: protein-coding
Summary: The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on ... |
Does Knockout of RPS6KC1 in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | RPS6KC1 | cell proliferation | T-lymphoma cell line | Gene: RPS6KC1 (ribosomal protein S6 kinase C1)
Type: protein-coding
Summary: Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sp... |
Does Knockout of HAUS8 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 815 | Knockout | HAUS8 | cell proliferation | Colonic Cancer Cell Line | Gene: HAUS8 (HAUS augmin like complex subunit 8)
Type: protein-coding
Summary: HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin compl... |
Does Knockout of VSIG2 in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | VSIG2 | cell proliferation | Colorectal Cancer Cell Line | Gene: VSIG2 (V-set and immunoglobulin domain containing 2)
Type: protein-coding
Summary: Predicted to be located in membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: membrane, plasma membrane
Pathway... |
Does Knockout of COG2 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 1 | 1,978 | Knockout | COG2 | response to chemicals | Monocytic Leukemia Cell Line | Gene: COG2 (component of oligomeric golgi complex 2)
Type: protein-coding
Summary: This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle d... |
Does Knockout of MAGOHB in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,576 | Knockout | MAGOHB | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: MAGOHB (mago homolog B, exon junction complex subunit)
Type: protein-coding
Summary: Enables RNA binding activity. Involved in mRNA splicing, via spliceosome and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in nucleus. Part of U2-type catalytic step 1 spliceosome; U... |
Does Knockout of MED6 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | MED6 | cell proliferation | Monocytic Leukemia Cell Line | Gene: MED6 (mediator complex subunit 6)
Type: protein-coding
Summary: Enables transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of mediator complex. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of ZMYM5 in Breast Cancer Cell Line causally result in cell proliferation? | 0 | 235 | Knockout | ZMYM5 | cell proliferation | Breast Cancer Cell Line | Gene: ZMYM5 (zinc finger MYM-type containing 5)
Type: protein-coding
Summary: Predicted to enable zinc ion binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontol... |
Does Knockout of LAPTM5 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 149 | Knockout | LAPTM5 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: LAPTM5 (lysosomal protein transmembrane 5)
Type: protein-coding
Summary: This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis. [provided by RefSeq, Feb 2009].
Gene Ontology: BP: Golgi ... |
Does Knockout of IPO7 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 149 | Knockout | IPO7 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: IPO7 (importin 7)
Type: protein-coding
Summary: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequenc... |
Does Knockout of IER5 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | IER5 | cell proliferation | Cancer Cell Line | Gene: IER5 (immediate early response 5)
Type: protein-coding
Summary: This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the express... |
Does Knockout of DCTD in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | DCTD | cell proliferation | T-lymphoma cell line | Gene: DCTD (dCMP deaminase)
Type: protein-coding
Summary: The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This prot... |
Does Activation of ABRA in T cell causally result in protein/peptide accumulation? | 0 | 2,425 | Activation | ABRA | protein/peptide accumulation | T cell | Gene: ABRA (actin binding Rho activating protein)
Type: protein-coding
Summary: Predicted to enable actin binding activity. Predicted to be involved in positive regulation of DNA-binding transcription factor activity; positive regulation of Rho protein signal transduction; and positive regulation of tra... |
Does Knockout of TMED10 in Cancer Cell Line causally result in cell proliferation? | 1 | 1,308 | Knockout | TMED10 | cell proliferation | Cancer Cell Line | Gene: TMED10 (transmembrane p24 trafficking protein 10)
Type: protein-coding
Summary: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein tr... |
Does Activation of RNF150 in T cell causally result in protein/peptide accumulation? | 0 | 2,425 | Activation | RNF150 | protein/peptide accumulation | T cell | Gene: RNF150 (ring finger protein 150)
Type: protein-coding
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Allianc... |
Does Knockout of CHMP4B in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | CHMP4B | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: CHMP4B (charged multivesicular body protein 4B)
Type: protein-coding
Summary: This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ES... |
Does Knockout of PRCC in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 427 | Knockout | PRCC | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: PRCC (proline rich mitotic checkpoint control factor)
Type: protein-coding
Summary: This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal ce... |
Does Knockout of GYG1 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,329 | Knockout | GYG1 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: GYG1 (glycogenin 1)
Type: protein-coding
Summary: This gene encodes a member of the glycogenin family. Glycogenin is a glycosyltransferase that catalyzes the formation of a short glucose polymer from uridine diphosphate glucose in an autoglucosylation reaction. This reaction is followed by elongat... |
Does Knockout of LENG8 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | LENG8 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: LENG8 (leukocyte receptor cluster member 8)
Type: protein-coding
Summary: Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: nucleus, protein-containing complex
Pathways:
UniProt: Q96PV6
Entrez ID: 114823 |
Does Knockout of GPR88 in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | GPR88 | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: GPR88 (G protein-coupled receptor 88)
Type: protein-coding
Summary: The protein encoded by this gene is a G protein-coupled receptor found almost exclusively in the striatum, a brain structure that controls motor function and cognition. Defects in this gene have been associated with chorea, speech... |
Does Knockout of CCDC7 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,658 | Knockout | CCDC7 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: CCDC7 (coiled-coil domain containing 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q96M83
Entrez ID: 79741 |
Does Knockout of ROR2 in Huh-7 Cell causally result in response to virus? | 0 | 1,382 | Knockout | ROR2 | response to virus | Huh-7 Cell | Gene: ROR2 (receptor tyrosine kinase like orphan receptor 2)
Type: protein-coding
Summary: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early format... |
Does Knockout of IBA57 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,459 | Knockout | IBA57 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: IBA57 (iron-sulfur cluster assembly factor IBA57)
Type: protein-coding
Summary: The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects ... |
Does Knockout of ZNF177 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 865 | Knockout | ZNF177 | cell proliferation | Colonic Cancer Cell Line | Gene: ZNF177 (zinc finger protein 177)
Type: protein-coding
Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in blood microparticle. [provided by Alliance of Genome Resources, Apr 2022]... |
Does Knockout of TNFSF15 in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | TNFSF15 | cell proliferation | Renal Cancer Cell Line | Gene: TNFSF15 (TNF superfamily member 15)
Type: protein-coding
Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of ... |
Does Knockout of SYDE1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 80 | Knockout | SYDE1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SYDE1 (synapse defective Rho GTPase activating protein 1)
Type: protein-coding
Summary: The protein encoded by this gene is a Rho GTPase-activating protein highly expressed in placenta. The encoded protein is involved in cytoskeletal remodeling and trophoblast cell migration. Decreased expression ... |
Does Knockout of IMMT in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | IMMT | cell proliferation | Multiple Myeloma Cell Line | Gene: IMMT (inner membrane mitochondrial protein)
Type: protein-coding
Summary: Enables RNA binding activity. Involved in cristae formation. Located in mitochondrial inner membrane. Part of MICOS complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: cristae formation,... |
Does Knockout of PLEKHG6 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,576 | Knockout | PLEKHG6 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6)
Type: protein-coding
Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Located in cell junction and centrosome. [provided by All... |
Does Knockout of CIB4 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 387 | Knockout | CIB4 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: CIB4 (calcium and integrin binding family member 4)
Type: protein-coding
Summary: Enables calcium ion binding activity and magnesium ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: calcium ion binding, magnesium ion binding, metal ion binding,... |
Does Knockout of SAE1 in Hepatoma Cell Line causally result in response to virus? | 1 | 2,437 | Knockout | SAE1 | response to virus | Hepatoma Cell Line | Gene: SAE1 (SUMO1 activating enzyme subunit 1)
Type: protein-coding
Summary: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterod... |
Does Knockout of CRCP in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | CRCP | cell proliferation | Melanoma Cell Line | Gene: CRCP (CGRP receptor component)
Type: protein-coding
Summary: This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been charac... |
Does Knockout of PRELID3B in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | PRELID3B | cell proliferation | Monocytic Leukemia Cell Line | Gene: PRELID3B (PRELI domain containing 3B)
Type: protein-coding
Summary: Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be active in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of FAM219B in Monocytic Leukemia Cell Line causally result in response to chemicals? | 1 | 1,978 | Knockout | FAM219B | response to chemicals | Monocytic Leukemia Cell Line | Gene: FAM219B (family with sequence similarity 219 member B)
Type: protein-coding
Summary: family with sequence similarity 219 member B
Gene Ontology:
Pathways:
UniProt: Q5XKK7
Entrez ID: 57184 |
Does Activation of CDK4 in T cell causally result in protein/peptide accumulation? | 1 | 2,425 | Activation | CDK4 | protein/peptide accumulation | T cell | Gene: CDK4 (cyclin dependent kinase 4)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex th... |
Does Knockout of SLFNL1 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 1,813 | Knockout | SLFNL1 | cell proliferation | Medulloblastoma Cell Line | Gene: SLFNL1 (schlafen like 1)
Type: protein-coding
Summary: Predicted to enable ATP binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: ATP binding, nucleotide binding
Pathways:
UniProt: Q499Z3
Entrez ID: 200172 |
Does Knockout of TUBA1B in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | TUBA1B | cell proliferation | Colorectal Cancer Cell Line | Gene: TUBA1B (tubulin alpha 1b)
Type: protein-coding
Summary: Enables double-stranded RNA binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within cellular response to ... |
Does Knockout of IVL in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | IVL | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: IVL (involucrin)
Type: protein-coding
Summary: Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, a... |
Does Knockout of MYMK in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | MYMK | response to virus | Hepatoma Cell Line | Gene: MYMK (myomaker, myoblast fusion factor)
Type: protein-coding
Summary: Involved in myoblast fusion. Located in plasma membrane. Implicated in Carey-Fineman-Ziter syndrome. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: muscle organ development, myoblast fusion, myo... |
Does Knockout of CLP1 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | CLP1 | cell proliferation | Medulloblastoma Cell Line | Gene: CLP1 (cleavage factor polyribonucleotide kinase subunit 1)
Type: protein-coding
Summary: This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II... |
Does Knockout of CHMP7 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | CHMP7 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: CHMP7 (charged multivesicular body protein 7)
Type: protein-coding
Summary: Involved in several processes, including late endosome to vacuole transport; midbody abscission; and mitotic nuclear division. Located in cytosol; nuclear envelope; and nucleoplasm. Part of ESCRT III complex. Colocalizes w... |
Does Knockout of EYA4 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,576 | Knockout | EYA4 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: EYA4 (EYA transcriptional coactivator and phosphatase 4)
Type: protein-coding
Summary: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye develo... |
Does Knockout of NOL12 in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | NOL12 | cell proliferation | Breast Cancer Cell Line | Gene: NOL12 (nucleolar protein 12)
Type: protein-coding
Summary: Enables identical protein binding activity. Predicted to be active in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: RNA binding, identical protein binding, protein binding, rRNA binding, single... |
Does Knockout of POLRMT in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | POLRMT | cell proliferation | Monocytic Leukemia Cell Line | Gene: POLRMT (RNA polymerase mitochondrial)
Type: protein-coding
Summary: This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Altho... |
Does Knockout of TLX1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 69 | Knockout | TLX1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: TLX1 (T cell leukemia homeobox 1)
Type: protein-coding
Summary: This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is al... |
Does Knockout of VPREB1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | VPREB1 | cell proliferation | Colonic Cancer Cell Line | Gene: VPREB1 (V-set pre-B cell surrogate light chain 1)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polype... |
Does Knockout of XPO7 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 287 | Knockout | XPO7 | cell proliferation | Endometrial Cancer Cell Line | Gene: XPO7 (exportin 7)
Type: protein-coding
Summary: The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of b... |
Does Knockout of NPIPA1 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | NPIPA1 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: NPIPA1 (nuclear pore complex interacting protein family member A1)
Type: protein-coding
Summary: Predicted to be involved in mRNA transport and protein transport. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: mRNA transport, protein transp... |
Does Knockout of SORL1 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | SORL1 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: SORL1 (sortilin related receptor 1)
Type: protein-coding
Summary: This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also co... |
Does Knockout of SMCO4 in Huh-7 Cell causally result in response to virus? | 0 | 1,382 | Knockout | SMCO4 | response to virus | Huh-7 Cell | Gene: SMCO4 (single-pass membrane protein with coiled-coil domains 4)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
UniProt: Q9NRQ5
Entrez ID: 56935 |
Does Knockout of IMP3 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | IMP3 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: IMP3 (IMP U3 small nucleolar ribonucleoprotein 3)
Type: protein-coding
Summary: This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008].
... |
Does Knockout of IL22RA1 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | IL22RA1 | cell proliferation | Glioblastoma Cell Line | Gene: IL22RA1 (interleukin 22 receptor subunit alpha 1)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and int... |
Does Knockout of TCEAL2 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,340 | Knockout | TCEAL2 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: TCEAL2 (transcription elongation factor A like 2)
Type: protein-coding
Summary: This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in ... |
Does Knockout of MED29 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | MED29 | cell proliferation | Gastric Cancer Cell Line | Gene: MED29 (mediator complex subunit 29)
Type: protein-coding
Summary: MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2... |
Does Knockout of CTCF in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | CTCF | cell proliferation | Ewing's Sarcoma Cell Line | Gene: CTCF (CCCTC-binding factor)
Type: protein-coding
Summary: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind di... |
Does Knockout of AASS in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,576 | Knockout | AASS | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: AASS (aminoadipate-semialdehyde synthase)
Type: protein-coding
Summary: This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and sacch... |
Does Knockout of WDR74 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | WDR74 | cell proliferation | Endometrial Cancer Cell Line | Gene: WDR74 (WD repeat domain 74)
Type: protein-coding
Summary: Involved in rRNA processing and ribosomal large subunit biogenesis. Located in nucleoplasm. Colocalizes with nuclear exosome (RNase complex) and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: RNA... |
Does Knockout of UBE2E1 in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | UBE2E1 | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: UBE2E1 (ubiquitin conjugating enzyme E2 E1)
Type: protein-coding
Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating e... |
Does Knockout of CNTNAP1 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 334 | Knockout | CNTNAP1 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: CNTNAP1 (contactin associated protein 1)
Type: protein-coding
Summary: The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellul... |
Does Knockout of FAF2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | FAF2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: FAF2 (Fas associated factor family member 2)
Type: protein-coding
Summary: The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed... |
Does Knockout of METTL5 in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | METTL5 | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: METTL5 (methyltransferase 5, N6-adenosine)
Type: protein-coding
Summary: Enables S-adenosyl-L-methionine binding activity and rRNA (adenine-N6-)-methyltransferase activity. Involved in positive regulation of translation and rRNA methylation. Located in nucleus; postsynapse; and presynapse. Implica... |
Does Knockout of LHPP in Lung Cancer Cell Line causally result in response to virus? | 0 | 1,433 | Knockout | LHPP | response to virus | Lung Cancer Cell Line | Gene: LHPP (phospholysine phosphohistidine inorganic pyrophosphate phosphatase)
Type: protein-coding
Summary: Enables inorganic diphosphatase activity and protein homodimerization activity. Involved in phosphate-containing compound metabolic process. Located in cytosol and nuclear speck. [provided by Al... |
Does Knockout of GPRIN2 in Cancer Cell Line causally result in cell proliferation? | 0 | 948 | Knockout | GPRIN2 | cell proliferation | Cancer Cell Line | Gene: GPRIN2 (G protein regulated inducer of neurite outgrowth 2)
Type: protein-coding
Summary: Predicted to be involved in neuron projection development. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
... |
Does Knockout of ANGEL2 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | ANGEL2 | cell proliferation | Colonic Cancer Cell Line | Gene: ANGEL2 (angel homolog 2)
Type: protein-coding
Summary: Enables mRNA 3'-UTR binding activity. Involved in 3'-UTR-mediated mRNA stabilization and negative regulation of mitotic cell cycle. Located in Cajal body and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontolog... |
Does Knockout of COG3 in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | COG3 | cell proliferation | Bladder Carcinoma | Gene: COG3 (component of oligomeric golgi complex 3)
Type: protein-coding
Summary: This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result i... |
Does Knockout of JAG1 in Melanoma Cell Line causally result in response to chemicals? | 1 | 1,940 | Knockout | JAG1 | response to chemicals | Melanoma Cell Line | Gene: JAG1 (jagged canonical Notch ligand 1)
Type: protein-coding
Summary: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 ... |
Does Knockout of AK1 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | AK1 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: AK1 (adenylate kinase 1)
Type: protein-coding
Summary: This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes.... |
Does Knockout of IGFBP5 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 951 | Knockout | IGFBP5 | cell proliferation | Colonic Cancer Cell Line | Gene: IGFBP5 (insulin like growth factor binding protein 5)
Type: protein-coding
Summary: Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferat... |
Does Knockout of NIPAL1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | NIPAL1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: NIPAL1 (NIPA like domain containing 1)
Type: protein-coding
Summary: Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance ... |
Does Knockout of ASB15 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | ASB15 | cell proliferation | Gastric Cancer Cell Line | Gene: ASB15 (ankyrin repeat and SOCS box containing 15)
Type: protein-coding
Summary: This gene encodes a member of the suppressor of cytokine signaling box superfamily. The proteins in this superfamily participate in the ubiquitin-proteasome system for the degradation of proteins in the cell cycle and ... |
Does Knockout of WDR5 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | WDR5 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: WDR5 (WD repeat domain 5)
Type: protein-coding
Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or mul... |
Does Knockout of E2F6 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 334 | Knockout | E2F6 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: E2F6 (E2F transcription factor 6)
Type: protein-coding
Summary: This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains fou... |
Does Knockout of TGM2 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | TGM2 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: TGM2 (transglutaminase 2)
Type: protein-coding
Summary: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their... |
Does Knockout of CROCC in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | CROCC | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: CROCC (ciliary rootlet coiled-coil, rootletin)
Type: protein-coding
Summary: Predicted to enable kinesin binding activity and structural molecule activity. Involved in several processes, including centriole-centriole cohesion; positive regulation of cilium assembly; and positive regulation of prot... |
Does Knockout of MAOA in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | MAOA | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: MAOA (monoamine oxidase A)
Type: protein-coding
Summary: This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome.... |
Does Knockout of TIPIN in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | TIPIN | cell proliferation | Breast Cancer Cell Line | Gene: TIPIN (TIMELESS interacting protein)
Type: protein-coding
Summary: The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM, which is involved in circadian rhythm regulation, and aids in protecting cells against DNA damage an... |
Does Knockout of KRT40 in Melanoma Cell Line causally result in cell proliferation? | 0 | 527 | Knockout | KRT40 | cell proliferation | Melanoma Cell Line | Gene: KRT40 (keratin 40)
Type: protein-coding
Summary: This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along ... |
Does Knockout of PDCL2 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | PDCL2 | cell proliferation | Colonic Cancer Cell Line | Gene: PDCL2 (phosducin like 2)
Type: protein-coding
Summary: This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family ha... |
Does Knockout of MED6 in Astrocytoma Cell Line causally result in cell proliferation? | 1 | 904 | Knockout | MED6 | cell proliferation | Astrocytoma Cell Line | Gene: MED6 (mediator complex subunit 6)
Type: protein-coding
Summary: Enables transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of mediator complex. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of DNAH12 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 149 | Knockout | DNAH12 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: DNAH12 (dynein axonemal heavy chain 12)
Type: protein-coding
Summary: Predicted to enable several functions, including ATP binding activity; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Pre... |
Does Knockout of RRP7A in Ovarian Cancer Cell Line causally result in cell proliferation? | 1 | 699 | Knockout | RRP7A | cell proliferation | Ovarian Cancer Cell Line | Gene: RRP7A (ribosomal RNA processing 7 homolog A)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit assembly. Predicted to act upstream of or within blastocyst formation. Predicted to be located in nucleoplasm. Predicted ... |
Does Knockout of EIF4E in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | EIF4E | cell proliferation | Multiple Myeloma Cell Line | Gene: EIF4E (eukaryotic translation initiation factor 4E)
Type: protein-coding
Summary: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein ai... |
Does Knockout of HUS1B in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | HUS1B | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: HUS1B (HUS1 checkpoint clamp component B)
Type: protein-coding
Summary: The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point p... |
Does Knockout of RHBDD3 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | RHBDD3 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RHBDD3 (rhomboid domain containing 3)
Type: protein-coding
Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within several processes, including liver development; negative regulation of natural killer cell act... |
Does Knockout of ZSCAN5B in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 951 | Knockout | ZSCAN5B | cell proliferation | Colonic Cancer Cell Line | Gene: ZSCAN5B (zinc finger and SCAN domain containing 5B)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of ... |
Does Knockout of ZNF705D in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 427 | Knockout | ZNF705D | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: ZNF705D (zinc finger protein 705D)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulatio... |
Does Knockout of TMEM270 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | TMEM270 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: TMEM270 (transmembrane protein 270)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
UniProt: Q6UE05
Entrez ID: 135886 |
Does Knockout of GINS4 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | GINS4 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: GINS4 (GINS complex subunit 4)
Type: protein-coding
Summary: The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast a... |
Does Knockout of TRIQK in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 787 | Knockout | TRIQK | cell proliferation | Gastric Cancer Cell Line | Gene: TRIQK (triple QxxK/R motif containing)
Type: protein-coding
Summary: Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: endoplasmic reticulum, endoplasmic reticu... |
Does Knockout of DHX36 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | DHX36 | cell proliferation | Medulloblastoma Cell Line | Gene: DHX36 (DEAH-box helicase 36)
Type: protein-coding
Summary: This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and dec... |
Does Knockout of MIR3166 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | MIR3166 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: MIR3166 (microRNA 3166)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase... |
Does Knockout of USH1G in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,339 | Knockout | USH1G | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: USH1G (USH1 protein network component sans)
Type: protein-coding
Summary: This gene encodes a protein that contains three ankyrin domains, a class I PDZ-binding motif and a sterile alpha motif. The encoded protein interacts with harmonin, which is associated with Usher syndrome type 1C. This prote... |
Does Knockout of DEAF1 in Non-Small Cell Lung Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 1,391 | Knockout | DEAF1 | response to chemicals | Non-Small Cell Lung Adenocarcinoma Cell Line | Gene: DEAF1 (DEAF1 transcription factor)
Type: protein-coding
Summary: This gene encodes a zinc finger domain-containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is importan... |
Does Knockout of MAT2A in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | MAT2A | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: MAT2A (methionine adenosyltransferase 2A)
Type: protein-coding
Summary: The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011].
Gene Ontology: ... |
Does Knockout of DCTN2 in acute lymphoblastic leukemia cell line causally result in cell proliferation? | 1 | 1,957 | Knockout | DCTN2 | cell proliferation | acute lymphoblastic leukemia cell line | Gene: DCTN2 (dynactin subunit 2)
Type: protein-coding
Summary: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular... |
Does Knockout of GPX8 in Neuroblastoma Cell Line causally result in cell proliferation? | 0 | 824 | Knockout | GPX8 | cell proliferation | Neuroblastoma Cell Line | Gene: GPX8 (glutathione peroxidase 8 (putative))
Type: protein-coding
Summary: Enables peroxidase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in endoplasmic reticulum lumen. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontolo... |
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