prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of FSTL5 in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | FSTL5 | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: FSTL5 (follistatin like 5)
Type: protein-coding
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in cell differentiation. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: cell differ... |
Does Knockout of MED7 in Prostate Cancer Cell Line causally result in cell proliferation? | 1 | 843 | Knockout | MED7 | cell proliferation | Prostate Cancer Cell Line | Gene: MED7 (mediator complex subunit 7)
Type: protein-coding
Summary: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polym... |
Does Knockout of F13B in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 0 | 763 | Knockout | F13B | cell proliferation | Ewing's Sarcoma Cell Line | Gene: F13B (coagulation factor XIII B chain)
Type: protein-coding
Summary: This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subuni... |
Does Knockout of DXO in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | DXO | cell proliferation | Bladder Carcinoma | Gene: DXO (decapping exoribonuclease)
Type: protein-coding
Summary: This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes sug... |
Does Knockout of TOR4A in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | TOR4A | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: TOR4A (torsin family 4 member A)
Type: protein-coding
Summary: Predicted to enable ATP binding activity. Predicted to be located in extracellular region and platelet alpha granule lumen. Predicted to be active in endoplasmic reticulum lumen and nuclear envelope. [provided by Alliance of Genome Res... |
Does Knockout of NR6A1 in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | NR6A1 | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: NR6A1 (nuclear receptor subfamily 6 group A member 1)
Type: protein-coding
Summary: This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein ... |
Does Knockout of PTPN3 in Primary Effusion Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,061 | Knockout | PTPN3 | response to chemicals | Primary Effusion Lymphoma Cell Line | Gene: PTPN3 (protein tyrosine phosphatase non-receptor type 3)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differ... |
Does Knockout of TAS2R42 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | TAS2R42 | cell proliferation | Colonic Cancer Cell Line | Gene: TAS2R42 (taste 2 receptor member 42)
Type: protein-coding
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of taste. Is integral component of membrane. [provided by Alliance of Genome R... |
Does Knockout of HMX3 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 1 | 1,397 | Knockout | HMX3 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: HMX3 (H6 family homeobox 3)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in ear development and regulati... |
Does Knockout of CNN2 in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | CNN2 | cell proliferation | Renal Cancer Cell Line | Gene: CNN2 (calponin 2)
Type: protein-coding
Summary: The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Sev... |
Does Knockout of NCK1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 287 | Knockout | NCK1 | cell proliferation | Endometrial Cancer Cell Line | Gene: NCK1 (NCK adaptor protein 1)
Type: protein-coding
Summary: The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from recepto... |
Does Knockout of DNTTIP2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | DNTTIP2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: DNTTIP2 (deoxynucleotidyltransferase terminal interacting protein 2)
Type: protein-coding
Summary: This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and ... |
Does Knockout of SCMH1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | SCMH1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SCMH1 (Scm polycomb group protein homolog 1)
Type: protein-coding
Summary: Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within anterior/posterior pattern... |
Does Knockout of PPP2R3C in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | PPP2R3C | cell proliferation | Medulloblastoma Cell Line | Gene: PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma)
Type: protein-coding
Summary: This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous c... |
Does Knockout of PKD2L1 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 787 | Knockout | PKD2L1 | cell proliferation | Gastric Cancer Cell Line | Gene: PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel)
Type: protein-coding
Summary: This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membran... |
Does Knockout of CLPB in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | CLPB | cell proliferation | Colonic Cancer Cell Line | Gene: CLPB (ClpB family mitochondrial disaggregase)
Type: protein-coding
Summary: This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in var... |
Does Knockout of ISG20L2 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 1,813 | Knockout | ISG20L2 | cell proliferation | Medulloblastoma Cell Line | Gene: ISG20L2 (interferon stimulated exonuclease gene 20 like 2)
Type: protein-coding
Summary: This gene encodes a 3'-5' exoribonuclease that may be involved in the processing of the 12S pre-rRNA. Pseudogenes have been identified on chromosomes 6 and 11. [provided by RefSeq, Dec 2014].
Gene Ont... |
Does Knockout of RIC1 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 334 | Knockout | RIC1 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: RIC1 (RIC1 partner of RAB6A GEF complex)
Type: protein-coding
Summary: Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including positive regulation of GTPase activity; regulation of extracellular matrix constituent secretion; an... |
Does Knockout of PIM2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | PIM2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: PIM2 (Pim-2 proto-oncogene, serine/threonine kinase)
Type: protein-coding
Summary: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009].
... |
Does Knockout of LSM4 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | LSM4 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: LSM4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated)
Type: protein-coding
Summary: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role... |
Does Knockout of FKBP11 in Neuroblastoma Cell Line causally result in cell proliferation? | 0 | 824 | Knockout | FKBP11 | cell proliferation | Neuroblastoma Cell Line | Gene: FKBP11 (FKBP prolyl isomerase 11)
Type: protein-coding
Summary: FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant co... |
Does Knockout of HERC6 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | HERC6 | cell proliferation | Gastric Cancer Cell Line | Gene: HERC6 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 6)
Type: protein-coding
Summary: HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted... |
Does Knockout of LGALS1 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | LGALS1 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: LGALS1 (galectin 1)
Type: protein-coding
Summary: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq... |
Does Knockout of RFFL in T-lymphoma cell line causally result in cell proliferation? | 1 | 478 | Knockout | RFFL | cell proliferation | T-lymphoma cell line | Gene: RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase)
Type: protein-coding
Summary: Enables enzyme binding activity; p53 binding activity; and ubiquitin protein ligase activity. Involved in cellular protein metabolic process; negative regulation of cysteine-type endopeptid... |
Does Knockout of AREL1 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,339 | Knockout | AREL1 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: AREL1 (apoptosis resistant E3 ubiquitin protein ligase 1)
Type: protein-coding
Summary: Enables ubiquitin-protein transferase activity. Involved in negative regulation of apoptotic process; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol. [provided by ... |
Does Knockout of MEPCE in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | MEPCE | cell proliferation | Monocytic Leukemia Cell Line | Gene: MEPCE (methylphosphate capping enzyme)
Type: protein-coding
Summary: Enables 7SK snRNA binding activity and RNA 5'-methyltransferase activity. Involved in RNA modification; positive regulation of protein localization to Cajal body; and positive regulation of snRNA transcription by RNA polymerase I... |
Does Knockout of SPINT3 in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 1 | 1,480 | Knockout | SPINT3 | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: SPINT3 (serine peptidase inhibitor, Kunitz type 3)
Type: protein-coding
Summary: Predicted to enable receptor antagonist activity and transforming growth factor beta binding activity. Predicted to be involved in negative regulation of transforming growth factor beta receptor signaling pathway. Pre... |
Does Knockout of NDUFAB1 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | NDUFAB1 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1)
Type: protein-coding
Summary: Predicted to enable acyl binding activity; acyl carrier activity; and fatty acid binding activity. Involved in mitochondrial respiratory chain complex I assembly and protein lipoylation. Located in mitochondrion and... |
Does Knockout of RBM48 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | RBM48 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: RBM48 (RNA binding motif protein 48)
Type: protein-coding
Summary: Predicted to enable RNA binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: RNA splicing, mRNA processing; MF: RNA binding, nucleic acid binding, protein bindin... |
Does Knockout of BAP1 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | BAP1 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: BAP1 (BRCA1 associated deubiquitinase 1)
Type: protein-coding
Summary: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility prot... |
Does Knockout of GPR142 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | GPR142 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: GPR142 (G protein-coupled receptor 142)
Type: protein-coding
Summary: GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008].
Gene Ontology: BP: G protein-coupled receptor signaling pathway... |
Does Knockout of CLPB in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | CLPB | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: CLPB (ClpB family mitochondrial disaggregase)
Type: protein-coding
Summary: This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in var... |
Does Activation of DRD3 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | DRD3 | protein/peptide accumulation | T cell | Gene: DRD3 (dopamine receptor D3)
Type: protein-coding
Summary: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which ar... |
Does Knockout of DDX21 in Neuroblastoma Cell Line causally result in cell proliferation? | 1 | 824 | Knockout | DDX21 | cell proliferation | Neuroblastoma Cell Line | Gene: DDX21 (DExD-box helicase 21)
Type: protein-coding
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiatio... |
Does Knockout of NOL12 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | NOL12 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: NOL12 (nucleolar protein 12)
Type: protein-coding
Summary: Enables identical protein binding activity. Predicted to be active in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: RNA binding, identical protein binding, protein binding, rRNA binding, single... |
Does Knockout of FLOT1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | FLOT1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: FLOT1 (flotillin 1)
Type: protein-coding
Summary: This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [p... |
Does Knockout of STK11 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | STK11 | cell proliferation | Medulloblastoma Cell Line | Gene: STK11 (serine/threonine kinase 11)
Type: protein-coding
Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghe... |
Does Knockout of KCTD20 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | KCTD20 | response to virus | Hepatoma Cell Line | Gene: KCTD20 (potassium channel tetramerization domain containing 20)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in positive regulation of phosphorylation. Predicted to be integral component of membrane. Predicted to be active in cytopl... |
Does Knockout of HAUS4 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | HAUS4 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: HAUS4 (HAUS augmin like complex subunit 4)
Type: protein-coding
Summary: This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome in... |
Does Knockout of HSPE1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 427 | Knockout | HSPE1 | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: HSPE1 (heat shock protein family E (Hsp10) member 1)
Type: protein-coding
Summary: This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodime... |
Does Knockout of TYROBP in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 149 | Knockout | TYROBP | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: TYROBP (transmembrane immune signaling adaptor TYROBP)
Type: protein-coding
Summary: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inh... |
Does Knockout of OR2T33 in Melanoma Cell Line causally result in cell proliferation? | 0 | 527 | Knockout | OR2T33 | cell proliferation | Melanoma Cell Line | Gene: OR2T33 (olfactory receptor family 2 subfamily T member 33)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of TCOF1 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | TCOF1 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: TCOF1 (treacle ribosome biogenesis factor 1)
Type: protein-coding
Summary: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been ass... |
Does Knockout of SARS2 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | SARS2 | cell proliferation | Colonic Cancer Cell Line | Gene: SARS2 (seryl-tRNA synthetase 2, mitochondrial)
Type: protein-coding
Summary: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis o... |
Does Knockout of GFER in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | GFER | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: GFER (growth factor, augmenter of liver regeneration)
Type: protein-coding
Summary: The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepa... |
Does Knockout of CHMP3 in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | CHMP3 | cell proliferation | Cancer Cell Line | Gene: CHMP3 (charged multivesicular body protein 3)
Type: protein-coding
Summary: This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESC... |
Does Knockout of POLR3D in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | POLR3D | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: POLR3D (RNA polymerase III subunit D)
Type: protein-coding
Summary: This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, ... |
Does Knockout of ZNF701 in Ovarian Cancer Cell Line causally result in cell proliferation? | 0 | 699 | Knockout | ZNF701 | cell proliferation | Ovarian Cancer Cell Line | Gene: ZNF701 (zinc finger protein 701)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RN... |
Does Knockout of SLC18A1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,032 | Knockout | SLC18A1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: SLC18A1 (solute carrier family 18 member A1)
Type: protein-coding
Summary: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the ... |
Does Knockout of RPS15 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 906 | Knockout | RPS15 | cell proliferation | Glioblastoma Cell Line | Gene: RPS15 (ribosomal protein S15)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of UBXN1 in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 734 | Knockout | UBXN1 | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: UBXN1 (UBX domain protein 1)
Type: protein-coding
Summary: Enables several functions, including enzyme binding activity; polyubiquitin modification-dependent protein binding activity; and proteasome regulatory particle binding activity. Involved in negative regulation of cellular protein metabolic... |
Does Knockout of PNN in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | PNN | cell proliferation | Monocytic Leukemia Cell Line | Gene: PNN (pinin, desmosome associated protein)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in cell adhesion and mRNA splicing, via spliceosome. Predicted to act upstream of or within cell-cell adhesion. Located in nuclear speck. Part of catalytic step 2 spliceos... |
Does Knockout of LUM in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | LUM | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: LUM (lumican)
Type: protein-coding
Summary: This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highl... |
Does Knockout of OGT in Lung Cancer Cell Line causally result in response to virus? | 0 | 1,433 | Knockout | OGT | response to virus | Lung Cancer Cell Line | Gene: OGT (O-linked N-acetylglucosamine (GlcNAc) transferase)
Type: protein-coding
Summary: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete fo... |
Does Knockout of NCKAP1L in Huh-7 Cell causally result in response to virus? | 0 | 1,382 | Knockout | NCKAP1L | response to virus | Huh-7 Cell | Gene: NCKAP1L (NCK associated protein 1 like)
Type: protein-coding
Summary: This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a p... |
Does Knockout of NOP53 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 0 | 1,978 | Knockout | NOP53 | response to chemicals | Monocytic Leukemia Cell Line | Gene: NOP53 (NOP53 ribosome biogenesis factor)
Type: protein-coding
Summary: Enables 5S rRNA binding activity; identical protein binding activity; and p53 binding activity. Involved in several processes, including negative regulation of transcription, DNA-templated; regulation of cellular protein metabo... |
Does Knockout of TRAPPC1 in Cancer Cell Line causally result in cell proliferation? | 1 | 1,308 | Knockout | TRAPPC1 | cell proliferation | Cancer Cell Line | Gene: TRAPPC1 (trafficking protein particle complex subunit 1)
Type: protein-coding
Summary: This gene product plays a role in vesicular transport of proteins to the Golgi apparatus from the endoplasmic reticulum. The encoded protein is a component of the multisubunit transport protein particle (TRAPP) ... |
Does Knockout of SRSF6 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 839 | Knockout | SRSF6 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: SRSF6 (serine and arginine rich splicing factor 6)
Type: protein-coding
Summary: The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown t... |
Does Knockout of MBNL1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,658 | Knockout | MBNL1 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: MBNL1 (muscleblind like splicing regulator 1)
Type: protein-coding
Summary: This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs.... |
Does Knockout of LEAP2 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,032 | Knockout | LEAP2 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: LEAP2 (liver enriched antimicrobial peptide 2)
Type: protein-coding
Summary: This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver. The mature peptide has activity against gram-positive bacteria and yeasts. [provided by RefSeq, Sep 2014].
... |
Does Knockout of BRD1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 149 | Knockout | BRD1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: BRD1 (bromodomain containing 1)
Type: protein-coding
Summary: This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of ... |
Does Knockout of SCN2A in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | SCN2A | cell proliferation | T-lymphoma cell line | Gene: SCN2A (sodium voltage-gated channel alpha subunit 2)
Type: protein-coding
Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulat... |
Does Knockout of WAC in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 906 | Knockout | WAC | cell proliferation | Glioblastoma Cell Line | Gene: WAC (WW domain containing adaptor with coiled-coil)
Type: protein-coding
Summary: The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short line... |
Does Knockout of HEATR3 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | HEATR3 | cell proliferation | Melanoma Cell Line | Gene: HEATR3 (HEAT repeat containing 3)
Type: protein-coding
Summary: The protein encoded by this gene plays a role in ribosomal protein transport and in the assembly of the 5S ribonucleoprotein particle (5S RNP). The encoded protein also may be involved in NOD2-mediated NF-kappaB signaling. [provided b... |
Does Knockout of ZC3H8 in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | ZC3H8 | cell proliferation | Breast Cancer Cell Line | Gene: ZC3H8 (zinc finger CCCH-type containing 8)
Type: protein-coding
Summary: Enables RNA binding activity. Involved in several processes, including positive regulation of thymocyte apoptotic process; regulation of transcription, DNA-templated; and snRNA transcription. Located in Cajal body; histone lo... |
Does Knockout of MED7 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | MED7 | cell proliferation | Endometrial Cancer Cell Line | Gene: MED7 (mediator complex subunit 7)
Type: protein-coding
Summary: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polym... |
Does Knockout of GLT8D2 in Primary Effusion Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,061 | Knockout | GLT8D2 | response to chemicals | Primary Effusion Lymphoma Cell Line | Gene: GLT8D2 (glycosyltransferase 8 domain containing 2)
Type: protein-coding
Summary: Predicted to enable glycosyltransferase activity. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:... |
Does Knockout of LEO1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | LEO1 | cell proliferation | Melanoma Cell Line | Gene: LEO1 (LEO1 component of Paf1/RNA polymerase II complex)
Type: protein-coding
Summary: LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransf... |
Does Knockout of DENND4C in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 305 | Knockout | DENND4C | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: DENND4C (DENN domain containing 4C)
Type: protein-coding
Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus; protein localization to plasma membrane; and regulation of Rab protein signal transduction. Located in Golgi appa... |
Does Knockout of MCM5 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | MCM5 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: MCM5 (minichromosome maintenance complex component 5)
Type: protein-coding
Summary: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of c... |
Does Knockout of CHCHD7 in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | CHCHD7 | cell proliferation | Colorectal Cancer Cell Line | Gene: CHCHD7 (coiled-coil-helix-coiled-coil-helix domain containing 7)
Type: protein-coding
Summary: Predicted to be located in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: mitochondrial intermembrane space, mitochondrion
Pa... |
Does Knockout of DHPS in Ovarian Cancer Cell Line causally result in cell proliferation? | 1 | 699 | Knockout | DHPS | cell proliferation | Ovarian Cancer Cell Line | Gene: DHPS (deoxyhypusine synthase)
Type: protein-coding
Summary: This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes t... |
Does Knockout of POU5F1B in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | POU5F1B | cell proliferation | Cancer Cell Line | Gene: POU5F1B (POU class 5 homeobox 1B)
Type: protein-coding
Summary: This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly simil... |
Does Knockout of LILRA2 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | LILRA2 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: LILRA2 (leukocyte immunoglobulin like receptor A2)
Type: protein-coding
Summary: This gene encodes a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The encoded protein is an activatin... |
Does Knockout of GOLPH3 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 1 | 2,368 | Knockout | GOLPH3 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: GOLPH3 (golgi phosphoprotein 3)
Type: protein-coding
Summary: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role ... |
Does Knockout of BRAT1 in Ovarian Cancer Cell Line causally result in cell proliferation? | 1 | 699 | Knockout | BRAT1 | cell proliferation | Ovarian Cancer Cell Line | Gene: BRAT1 (BRCA1 associated ATM activator 1)
Type: protein-coding
Summary: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of c... |
Does Knockout of POU2F3 in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | POU2F3 | cell proliferation | Colorectal Cancer Cell Line | Gene: POU2F3 (POU class 2 homeobox 3)
Type: protein-coding
Summary: This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primari... |
Does Knockout of OPTN in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | OPTN | response to virus | Cervical Adenocarcinoma Cell Line | Gene: OPTN (optineurin)
Type: protein-coding
Summary: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis f... |
Does Knockout of VPS53 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | VPS53 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: VPS53 (VPS53 subunit of GARP complex)
Type: protein-coding
Summary: This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. [provided by RefSeq, Jul 2008]
Gene Ontology: BP: cytosolic transport, ... |
Does Activation of TXNDC8 in Hepatoma Cell Line causally result in response to virus? | 1 | 1,210 | Activation | TXNDC8 | response to virus | Hepatoma Cell Line | Gene: TXNDC8 (thioredoxin domain containing 8)
Type: protein-coding
Summary: Involved in spermatogenesis. Located in Golgi apparatus. Biomarker of male infertility. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: cell differentiation, spermatogenesis; CC: Golgi apparatus... |
Does Knockout of WDR90 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | WDR90 | cell proliferation | Glioblastoma Cell Line | Gene: WDR90 (WD repeat domain 90)
Type: protein-coding
Summary: Involved in cilium assembly. Located in centriole. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: cell projection organization, centriole elongation, cilium assembly; MF: microtubule binding, protein bindin... |
Does Knockout of NDUFB6 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | NDUFB6 | cell proliferation | Monocytic Leukemia Cell Line | Gene: NDUFB6 (NADH:ubiquinone oxidoreductase subunit B6)
Type: protein-coding
Summary: The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. T... |
Does Knockout of CASZ1 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | CASZ1 | cell proliferation | Gastric Cancer Cell Line | Gene: CASZ1 (castor zinc finger 1)
Type: protein-coding
Summary: The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative spli... |
Does Knockout of ARIH1 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 897 | Knockout | ARIH1 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1)
Type: protein-coding
Summary: Enables enzyme binding activity; ubiquitin-protein transferase activity; and zinc ion binding activity. Involved in protein ubiquitination. Located in Lewy body; cytoplasm; and nuclear body. Colocalizes with cullin-RIN... |
Does Knockout of INPP4B in Neuroblastoma Cell Line causally result in cell proliferation? | 0 | 824 | Knockout | INPP4B | cell proliferation | Neuroblastoma Cell Line | Gene: INPP4B (inositol polyphosphate-4-phosphatase type II B)
Type: protein-coding
Summary: INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring ... |
Does Knockout of RBP7 in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | RBP7 | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: RBP7 (retinol binding protein 7)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally simi... |
Does Knockout of TRIM23 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | TRIM23 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: TRIM23 (tripartite motif containing 23)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a ... |
Does Knockout of SF3B5 in Ovarian Cancer Cell Line causally result in cell proliferation? | 1 | 699 | Knockout | SF3B5 | cell proliferation | Ovarian Cancer Cell Line | Gene: SF3B5 (splicing factor 3b subunit 5)
Type: protein-coding
Summary: Enables RNA binding activity and splicing factor binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U12-type spliceosomal complex and U2-type precatalytic spliceosome. [provided by Allianc... |
Does Knockout of FGFR1 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | FGFR1 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: FGFR1 (fibroblast growth factor receptor 1)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one... |
Does Knockout of ELP1 in Multiple Myeloma Cell Line causally result in cell proliferation? | 0 | 816 | Knockout | ELP1 | cell proliferation | Multiple Myeloma Cell Line | Gene: ELP1 (elongator acetyltransferase complex subunit 1)
Type: protein-coding
Summary: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases... |
Does Knockout of OLFML1 in Prostate Cancer Cell Line causally result in cell proliferation? | 0 | 843 | Knockout | OLFML1 | cell proliferation | Prostate Cancer Cell Line | Gene: OLFML1 (olfactomedin like 1)
Type: protein-coding
Summary: Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: extracellular region, extracellular space
Pathways:
UniProt: Q6UWY5
Entrez ID: 283... |
Does Knockout of POLR2H in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 897 | Knockout | POLR2H | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: POLR2H (RNA polymerase II, I and III subunit H)
Type: protein-coding
Summary: The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that ... |
Does Knockout of USP14 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 951 | Knockout | USP14 | cell proliferation | Colonic Cancer Cell Line | Gene: USP14 (ubiquitin specific peptidase 14)
Type: protein-coding
Summary: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiet... |
Does Knockout of HOXA11 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | HOXA11 | response to virus | Hepatoma Cell Line | Gene: HOXA11 (homeobox A11)
Type: protein-coding
Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryon... |
Does Knockout of RPL10A in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | RPL10A | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: RPL10A (ribosomal protein L10a)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene enco... |
Does Knockout of SHTN1 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,576 | Knockout | SHTN1 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: SHTN1 (shootin 1)
Type: protein-coding
Summary: Enables identical protein binding activity. Involved in positive regulation of neuron migration. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: Cdc42 protein signal transduction, Ras protein sig... |
Does Knockout of RNF212 in Huh-7 Cell causally result in response to virus? | 0 | 1,382 | Knockout | RNF212 | response to virus | Huh-7 Cell | Gene: RNF212 (ring finger protein 212)
Type: protein-coding
Summary: This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene ma... |
Does Knockout of ANPEP in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 287 | Knockout | ANPEP | cell proliferation | Endometrial Cancer Cell Line | Gene: ANPEP (alanyl aminopeptidase, membrane)
Type: protein-coding
Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydro... |
Does Knockout of ACTR10 in Neuroblastoma Cell Line causally result in cell proliferation? | 1 | 824 | Knockout | ACTR10 | cell proliferation | Neuroblastoma Cell Line | Gene: ACTR10 (actin related protein 10)
Type: protein-coding
Summary: Predicted to be involved in retrograde axonal transport of mitochondrion. Predicted to be located in cytosol; extracellular region; and secretory granule. Predicted to be part of dynactin complex. [provided by Alliance of Genome Resou... |
Does Knockout of NOD1 in Breast Cancer Cell Line causally result in cell proliferation? | 0 | 235 | Knockout | NOD1 | cell proliferation | Breast Cancer Cell Line | Gene: NOD1 (nucleotide binding oligomerization domain containing 1)
Type: protein-coding
Summary: This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recogniti... |
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