prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of CENPO in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | CENPO | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: CENPO (centromere protein O)
Type: protein-coding
Summary: This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling ... |
Does Knockout of PSMA3 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | PSMA3 | cell proliferation | Endometrial Cancer Cell Line | Gene: PSMA3 (proteasome 20S subunit alpha 3)
Type: protein-coding
Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 ri... |
Does Knockout of UTP6 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 906 | Knockout | UTP6 | cell proliferation | Glioblastoma Cell Line | Gene: UTP6 (UTP6 small subunit processome component)
Type: protein-coding
Summary: Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in chromosome and nucleolus. [provided by Alliance... |
Does Knockout of RRP9 in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | RRP9 | cell proliferation | Multiple Myeloma Cell Line | Gene: RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein)
Type: protein-coding
Summary: This gene encodes a member of the WD-repeat protein family. The encoded protein is a component of the nucleolar small nuclear ribonucleoprotein particle (snoRNP) and is essential for 18s rRNA pr... |
Does Knockout of RRP12 in Cancer Cell Line causally result in cell proliferation? | 1 | 1,308 | Knockout | RRP12 | cell proliferation | Cancer Cell Line | Gene: RRP12 (ribosomal RNA processing 12 homolog)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in cytosol; nucleolus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: RNA binding; CC:... |
Does Knockout of C3orf38 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | C3orf38 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: C3orf38 (chromosome 3 open reading frame 38)
Type: protein-coding
Summary: Involved in positive regulation of apoptotic process. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: apoptotic process, positive regulation of apoptotic process
... |
Does Knockout of PREB in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 1,813 | Knockout | PREB | cell proliferation | Medulloblastoma Cell Line | Gene: PREB (prolactin regulatory element binding)
Type: protein-coding
Summary: This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental ab... |
Does Knockout of POLR2K in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | POLR2K | cell proliferation | Multiple Myeloma Cell Line | Gene: POLR2K (RNA polymerase II, I and III subunit K)
Type: protein-coding
Summary: This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provide... |
Does Knockout of ALMS1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | ALMS1 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: ALMS1 (ALMS1 centrosome and basal body associated protein)
Type: protein-coding
Summary: This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and ma... |
Does Knockout of MED28 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,339 | Knockout | MED28 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: MED28 (mediator complex subunit 28)
Type: protein-coding
Summary: Predicted to enable actin binding activity. Predicted to act upstream of or within negative regulation of smooth muscle cell differentiation and stem cell population maintenance. Located in nucleoplasm. [provided by Alliance of Geno... |
Does Knockout of PPP3R1 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 787 | Knockout | PPP3R1 | cell proliferation | Gastric Cancer Cell Line | Gene: PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha)
Type: protein-coding
Summary: Enables cyclosporin A binding activity; phosphatase binding activity; and protein domain specific binding activity. Involved in calcineurin-NFAT signaling cascade and positive regulation of transcription by RN... |
Does Knockout of PSMA7 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | PSMA7 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: PSMA7 (proteasome 20S subunit alpha 7)
Type: protein-coding
Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are comp... |
Does Activation of IZUMO4 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | IZUMO4 | protein/peptide accumulation | T cell | Gene: IZUMO4 (IZUMO family member 4)
Type: protein-coding
Summary: Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: extracellular region, nucleus
Pathways: Acrosome Reaction and Sperm:Oocyte Membrane Binding, Fertilization, Reproduction
... |
Does Knockout of PYROXD1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | PYROXD1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1)
Type: protein-coding
Summary: This gene encodes a nuclear-cytoplasmic pyridine nucleotide-disulphide reductase (PNDR). PNDRs are flavoproteins that catalyze the pyridine nucleotide-dependent reduction of thiol residues in other prote... |
Does Knockout of TARDBP in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | TARDBP | cell proliferation | Multiple Myeloma Cell Line | Gene: TARDBP (TAR DNA binding protein)
Type: protein-coding
Summary: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is... |
Does Knockout of SULT1C4 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | SULT1C4 | cell proliferation | Glioblastoma Cell Line | Gene: SULT1C4 (sulfotransferase family 1C member 4)
Type: protein-coding
Summary: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificitie... |
Does Knockout of OSGEP in acute lymphoblastic leukemia cell line causally result in cell proliferation? | 1 | 1,957 | Knockout | OSGEP | cell proliferation | acute lymphoblastic leukemia cell line | Gene: OSGEP (O-sialoglycoprotein endopeptidase)
Type: protein-coding
Summary: Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Involved in tRNA threonylcarbamoyladenosine modification. Located in cytoplasm; nuclear speck; and plasma membrane. Part of ... |
Does Knockout of NOP2 in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | NOP2 | cell proliferation | Renal Cancer Cell Line | Gene: NOP2 (NOP2 nucleolar protein)
Type: protein-coding
Summary: Enables RNA binding activity. Involved in positive regulation of cell population proliferation; regulation of signal transduction by p53 class mediator; and ribosomal large subunit assembly. Located in nucleolus. [provided by Alliance of ... |
Does Knockout of UNC119B in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | UNC119B | cell proliferation | Monocytic Leukemia Cell Line | Gene: UNC119B (unc-119 lipid binding chaperone B)
Type: protein-coding
Summary: Enables lipid binding activity. Involved in cilium assembly and lipoprotein transport. Located in ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: cell projection orga... |
Does Knockout of OR52A5 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | OR52A5 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: OR52A5 (olfactory receptor family 52 subfamily A member 5)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of LANCL3 in Neuroblastoma Cell Line causally result in cell proliferation? | 1 | 824 | Knockout | LANCL3 | cell proliferation | Neuroblastoma Cell Line | Gene: LANCL3 (LanC like family member 3)
Type: protein-coding
Summary: Predicted to be involved in carbohydrate metabolic process. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: carbohydrate metabolic process, peptide modificat... |
Does Knockout of DNAJC17 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 815 | Knockout | DNAJC17 | cell proliferation | Colonic Cancer Cell Line | Gene: DNAJC17 (DnaJ heat shock protein family (Hsp40) member C17)
Type: protein-coding
Summary: Predicted to enable RNA binding activity. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and toxin transport. Predicted to be located in cytoplasm and nucleus... |
Does Knockout of ARL15 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | ARL15 | cell proliferation | Monocytic Leukemia Cell Line | Gene: ARL15 (ARF like GTPase 15)
Type: protein-coding
Summary: Predicted to enable GTP binding activity and GTPase activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: GTP binding, GTPase activity, molecular_function, nucleotide bin... |
Does Knockout of MIR891B in Hepatoma Cell Line causally result in response to virus? | 0 | 2,447 | Knockout | MIR891B | response to virus | Hepatoma Cell Line | Gene: MIR891B (microRNA 891b)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase... |
Does Knockout of PCDHGC3 in Cancer Cell Line causally result in cell proliferation? | 0 | 1,308 | Knockout | PCDHGC3 | cell proliferation | Cancer Cell Line | Gene: PCDHGC3 (protocadherin gamma subfamily C, 3)
Type: protein-coding
Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanis... |
Does Knockout of KIAA0408 in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | KIAA0408 | cell proliferation | Colorectal Cancer Cell Line | Gene: KIAA0408 (KIAA0408)
Type: protein-coding
Summary: KIAA0408
Gene Ontology:
Pathways:
UniProt: Q6ZU52
Entrez ID: 9729 |
Does Knockout of SDHB in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | SDHB | cell proliferation | Renal Cancer Cell Line | Gene: SDHB (succinate dehydrogenase complex iron sulfur subunit B)
Type: protein-coding
Summary: This tumor suppressor gene encodes the iron-sulfur protein subunit of the succinate dehydrogenase (SDH) enzyme complex which plays a critical role in mitochondria. The SDH enzyme complex is composed of four ... |
Does Knockout of LYPD8 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 80 | Knockout | LYPD8 | cell proliferation | Monocytic Leukemia Cell Line | Gene: LYPD8 (LY6/PLAUR domain containing 8)
Type: protein-coding
Summary: Predicted to be involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources... |
Does Knockout of LPCAT4 in Non-Small Cell Lung Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,631 | Knockout | LPCAT4 | response to chemicals | Non-Small Cell Lung Adenocarcinoma Cell Line | Gene: LPCAT4 (lysophosphatidylcholine acyltransferase 4)
Type: protein-coding
Summary: Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of al... |
Does Knockout of SKP2 in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | SKP2 | cell proliferation | Multiple Myeloma Cell Line | Gene: SKP2 (S-phase kinase associated protein 2)
Type: protein-coding
Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex call... |
Does Knockout of HK2 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 149 | Knockout | HK2 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: HK2 (hexokinase 2)
Type: protein-coding
Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. ... |
Does Knockout of RPL18A in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | RPL18A | cell proliferation | Monocytic Leukemia Cell Line | Gene: RPL18A (ribosomal protein L18a)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene enco... |
Does Knockout of SPOUT1 in Hepatoma Cell Line causally result in response to virus? | 1 | 2,437 | Knockout | SPOUT1 | response to virus | Hepatoma Cell Line | Gene: SPOUT1 (SPOUT domain containing methyltransferase 1)
Type: protein-coding
Summary: Enables miRNA binding activity. Involved in maintenance of centrosome location and production of miRNAs involved in gene silencing by miRNA. Located in kinetochore; mitotic spindle; and spindle pole centrosome. [pro... |
Does Activation of PAIP2B in Hepatoma Cell Line causally result in response to virus? | 0 | 1,210 | Activation | PAIP2B | response to virus | Hepatoma Cell Line | Gene: PAIP2B (poly(A) binding protein interacting protein 2B)
Type: protein-coding
Summary: Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation f... |
Does Knockout of RPL37 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | RPL37 | cell proliferation | Medulloblastoma Cell Line | Gene: RPL37 (ribosomal protein L37)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of SNRNP70 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | SNRNP70 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70)
Type: protein-coding
Summary: Enables U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Located in nucleoplasm. Part of U1 snRNP and spliceosomal complex. Implicated in disease of mental hea... |
Does Knockout of DHDDS in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | DHDDS | cell proliferation | Monocytic Leukemia Cell Line | Gene: DHDDS (dehydrodolichyl diphosphate synthase subunit)
Type: protein-coding
Summary: The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Muta... |
Does Knockout of DDC in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | DDC | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: DDC (dopa decarboxylase)
Type: protein-coding
Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase ... |
Does Knockout of RBM17 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | RBM17 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: RBM17 (RNA binding motif protein 17)
Type: protein-coding
Summary: This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related ps... |
Does Knockout of SUMO1 in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | SUMO1 | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: SUMO1 (small ubiquitin like modifier 1)
Type: protein-coding
Summary: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modifi... |
Does Knockout of SCX in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | SCX | response to virus | Cervical Adenocarcinoma Cell Line | Gene: SCX (scleraxis bHLH transcription factor)
Type: protein-coding
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and bHLH transcription factor binding activity. Contributes to E-box binding activity. Involved in positive regulation of transcription by RNA po... |
Does Knockout of MRPL13 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 1 | 1,397 | Knockout | MRPL13 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: MRPL13 (mitochondrial ribosomal protein L13)
Type: protein-coding
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.... |
Does Knockout of NDUFS3 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | NDUFS3 | cell proliferation | Melanoma Cell Line | Gene: NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3)
Type: protein-coding
Summary: This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial... |
Does Knockout of FIGN in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | FIGN | cell proliferation | Monocytic Leukemia Cell Line | Gene: FIGN (fidgetin, microtubule severing factor)
Type: protein-coding
Summary: Predicted to enable microtubule-severing ATPase activity. Predicted to be involved in cytoplasmic microtubule organization. Predicted to act upstream of or within locomotory behavior. Predicted to be located in nuclear matr... |
Does Activation of FSIP2 in Hepatoma Cell Line causally result in response to virus? | 1 | 1,210 | Activation | FSIP2 | response to virus | Hepatoma Cell Line | Gene: FSIP2 (fibrous sheath interacting protein 2)
Type: protein-coding
Summary: This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein en... |
Does Knockout of CRH in Breast Cancer Cell Line causally result in cell proliferation? | 0 | 235 | Knockout | CRH | cell proliferation | Breast Cancer Cell Line | Gene: CRH (corticotropin releasing hormone)
Type: protein-coding
Summary: This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the pa... |
Does Knockout of DMRT3 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,340 | Knockout | DMRT3 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: DMRT3 (doublesex and mab-3 related transcription factor 3)
Type: protein-coding
Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in male sex differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within... |
Does Knockout of ZBTB7A in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | ZBTB7A | cell proliferation | Colorectal Cancer Cell Line | Gene: ZBTB7A (zinc finger and BTB domain containing 7A)
Type: protein-coding
Summary: Enables several functions, including SMAD binding activity; androgen receptor binding activity; and transcription corepressor binding activity. Involved in several processes, including erythrocyte maturation; negative ... |
Does Knockout of REXO1L1P in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | REXO1L1P | cell proliferation | Monocytic Leukemia Cell Line | Gene: REXO1L1P (REXO1 like 1, pseudogene)
Type:
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt:
Entrez ID: |
Does Knockout of RPS27 in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | RPS27 | cell proliferation | Breast Cancer Cell Line | Gene: RPS27 (ribosomal protein S27)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene enc... |
Does Knockout of MED25 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | MED25 | cell proliferation | Glioblastoma Cell Line | Gene: MED25 (mediator complex subunit 25)
Type: protein-coding
Summary: This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromati... |
Does Knockout of MFSD6 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 305 | Knockout | MFSD6 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: MFSD6 (major facilitator superfamily domain containing 6)
Type: protein-coding
Summary: Predicted to enable MHC class I protein binding activity and MHC class I receptor activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class I. Located ... |
Does Knockout of SPART in Neuroblastoma Cell Line causally result in cell proliferation? | 0 | 824 | Knockout | SPART | cell proliferation | Neuroblastoma Cell Line | Gene: SPART (spartin)
Type: protein-coding
Summary: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes wi... |
Does Knockout of OR10T2 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,329 | Knockout | OR10T2 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: OR10T2 (olfactory receptor family 10 subfamily T member 2)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of FUCA1 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | FUCA1 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: FUCA1 (alpha-L-fucosidase 1)
Type: protein-coding
Summary: The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosom... |
Does Knockout of CNRIP1 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | CNRIP1 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: CNRIP1 (cannabinoid receptor interacting protein 1)
Type: protein-coding
Summary: This gene encodes a protein that interacts with the C-terminal tail of cannabinoid receptor 1. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013].
... |
Does Knockout of SLC25A37 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 758 | Knockout | SLC25A37 | cell proliferation | Endometrial Cancer Cell Line | Gene: SLC25A37 (solute carrier family 25 member 37)
Type: protein-coding
Summary: SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009 [PubMed ... |
Does Knockout of COL11A2 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | COL11A2 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: COL11A2 (collagen type XI alpha 2 chain)
Type: protein-coding
Summary: This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotri... |
Does Knockout of DMRT1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 80 | Knockout | DMRT1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: DMRT1 (doublesex and mab-3 related transcription factor 1)
Type: protein-coding
Summary: This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate ... |
Does Knockout of SNRNP40 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | SNRNP40 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: SNRNP40 (small nuclear ribonucleoprotein U5 subunit 40)
Type: protein-coding
Summary: This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger R... |
Does Knockout of UBA2 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | UBA2 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: UBA2 (ubiquitin like modifier activating enzyme 2)
Type: protein-coding
Summary: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form... |
Does Knockout of RPL18 in Cancer Cell Line causally result in cell proliferation? | 1 | 1,308 | Knockout | RPL18 | cell proliferation | Cancer Cell Line | Gene: RPL18 (ribosomal protein L18)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of SNAPC4 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 1 | 1,978 | Knockout | SNAPC4 | response to chemicals | Monocytic Leukemia Cell Line | Gene: SNAPC4 (small nuclear RNA activating complex polypeptide 4)
Type: protein-coding
Summary: This gene encodes the largest subunit of the small nuclear RNA-activating protein (SNAP) complex. The encoded protein contains a Myb DNA-binding domain, and is essential for RNA polymerase II and III polymera... |
Does Knockout of RPL34 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | RPL34 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RPL34 (ribosomal protein L34)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of RBX1 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | RBX1 | cell proliferation | Gastric Cancer Cell Line | Gene: RBX1 (ring-box 1)
Type: protein-coding
Summary: This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnove... |
Does Knockout of PELO in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | PELO | cell proliferation | Monocytic Leukemia Cell Line | Gene: PELO (pelota mRNA surveillance and ribosome rescue factor)
Type: protein-coding
Summary: This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq... |
Does Knockout of NR4A2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | NR4A2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: NR4A2 (nuclear receptor subfamily 4 group A member 2)
Type: protein-coding
Summary: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to ... |
Does Knockout of CELSR3 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 0 | 763 | Knockout | CELSR3 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3)
Type: protein-coding
Summary: This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane ... |
Does Knockout of GLRX in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | GLRX | cell proliferation | Colonic Cancer Cell Line | Gene: GLRX (glutaredoxin)
Type: protein-coding
Summary: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is ... |
Does Knockout of DYNC1H1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | DYNC1H1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: DYNC1H1 (dynein cytoplasmic 1 heavy chain 1)
Type: protein-coding
Summary: Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, in... |
Does Knockout of AIFM2 in Bladder Carcinoma causally result in cell proliferation? | 0 | 489 | Knockout | AIFM2 | cell proliferation | Bladder Carcinoma | Gene: AIFM2 (AIF family member 2)
Type: protein-coding
Summary: This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor... |
Does Knockout of FRG2 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | FRG2 | cell proliferation | Melanoma Cell Line | Gene: FRG2 (FSHD region gene 2)
Type: protein-coding
Summary: Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
UniProt: Q64ET8
Entrez ID: 448831 |
Does Knockout of HMOX2 in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | HMOX2 | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: HMOX2 (heme oxygenase 2)
Type: protein-coding
Summary: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced... |
Does Knockout of TELO2 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | TELO2 | cell proliferation | Endometrial Cancer Cell Line | Gene: TELO2 (telomere maintenance 2)
Type: protein-coding
Summary: This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.[provided by RefSeq, Mar 2009].
Gene Ontology: BP: 'de novo' cotranslational protein f... |
Does Knockout of ZMYND12 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 305 | Knockout | ZMYND12 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: ZMYND12 (zinc finger MYND-type containing 12)
Type: protein-coding
Summary: Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: flagellated sperm motility, sperm axoneme assembly; MF: metal ion binding, protein binding, z... |
Does Knockout of IFNA14 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | IFNA14 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: IFNA14 (interferon alpha 14)
Type: protein-coding
Summary: Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including B cell activation; lymphocyte activation involved in immune response; and positive regulation o... |
Does Knockout of DEFB105A in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 0 | 180 | Knockout | DEFB105A | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: DEFB105A (defensin beta 105A)
Type: protein-coding
Summary: Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins.... |
Does Knockout of HM13 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,114 | Knockout | HM13 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: HM13 (histocompatibility minor 13)
Type: protein-coding
Summary: The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal ... |
Does Knockout of SPTBN4 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | SPTBN4 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: SPTBN4 (spectrin beta, non-erythrocytic 4)
Type: protein-coding
Summary: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organizat... |
Does Knockout of PRDX4 in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | PRDX4 | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: PRDX4 (peroxiredoxin 4)
Type: protein-coding
Summary: The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and... |
Does Knockout of CCL1 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | CCL1 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: CCL1 (C-C motif chemokine ligand 1)
Type: protein-coding
Summary: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divide... |
Does Knockout of TPSG1 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 0 | 763 | Knockout | TPSG1 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: TPSG1 (tryptase gamma 1)
Type: protein-coding
Summary: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several trypt... |
Does Knockout of PARS2 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 387 | Knockout | PARS2 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: PARS2 (prolyl-tRNA synthetase 2, mitochondrial)
Type: protein-coding
Summary: This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encod... |
Does Knockout of CKAP4 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | CKAP4 | cell proliferation | Gastric Cancer Cell Line | Gene: CKAP4 (cytoskeleton associated protein 4)
Type: protein-coding
Summary: Enables RNA binding activity. Located in several cellular components, including lipid droplet; nuclear speck; and rough endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: RN... |
Does Knockout of C5orf24 in Colonic Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,736 | Knockout | C5orf24 | response to chemicals | Colonic Adenocarcinoma Cell Line | Gene: C5orf24 (chromosome 5 open reading frame 24)
Type: protein-coding
Summary: chromosome 5 open reading frame 24
Gene Ontology:
Pathways:
UniProt: Q7Z6I8
Entrez ID: 134553 |
Does Activation of POLR3GL in Hepatoma Cell Line causally result in response to virus? | 1 | 1,210 | Activation | POLR3GL | response to virus | Hepatoma Cell Line | Gene: POLR3GL (RNA polymerase III subunit GL)
Type: protein-coding
Summary: Predicted to enable chromatin binding activity. Involved in transcription by RNA polymerase III. Located in nucleus. Part of RNA polymerase III complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology... |
Does Knockout of MPPE1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 287 | Knockout | MPPE1 | cell proliferation | Endometrial Cancer Cell Line | Gene: MPPE1 (metallophosphoesterase 1)
Type: protein-coding
Summary: Predicted to enable GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Involved in GPI anchor biosynthetic process. Located in Golgi apparatus and nucleoplasm... |
Does Knockout of GATA3 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | GATA3 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: GATA3 (GATA binding protein 3)
Type: protein-coding
Summary: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell bi... |
Does Knockout of ANAPC13 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 0 | 763 | Knockout | ANAPC13 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: ANAPC13 (anaphase promoting complex subunit 13)
Type: protein-coding
Summary: This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The en... |
Does Knockout of CIC in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,119 | Knockout | CIC | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: CIC (capicua transcriptional repressor)
Type: protein-coding
Summary: The protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG d... |
Does Knockout of LAMTOR4 in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | LAMTOR4 | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: LAMTOR4 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 4)
Type: protein-coding
Summary: Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cellular response to amino acid stimulus; positive regulation of TO... |
Does Knockout of CYP2C19 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | CYP2C19 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: CYP2C19 (cytochrome P450 family 2 subfamily C member 19)
Type: protein-coding
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, s... |
Does Knockout of TAF7 in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | TAF7 | cell proliferation | Cancer Cell Line | Gene: TAF7 (TATA-box binding protein associated factor 7)
Type: protein-coding
Summary: The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, ... |
Does Knockout of GID8 in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | GID8 | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: GID8 (GID complex subunit 8 homolog)
Type: protein-coding
Summary: Predicted to enable protein homodimerization activity. Involved in positive regulation of canonical Wnt signaling pathway and positive regulation of cell population proliferation. Located in cell junction; cytosol; and nucleoplasm.... |
Does Knockout of NAT2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,459 | Knockout | NAT2 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: NAT2 (N-acetyltransferase 2)
Type: protein-coding
Summary: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate in... |
Does Knockout of MIR149 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 1 | 1,978 | Knockout | MIR149 | response to chemicals | Monocytic Leukemia Cell Line | Gene: MIR149 (microRNA 149)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I... |
Does Knockout of NSF in acute lymphoblastic leukemia cell line causally result in cell proliferation? | 1 | 1,957 | Knockout | NSF | cell proliferation | acute lymphoblastic leukemia cell line | Gene: NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase)
Type: protein-coding
Summary: Enables PDZ domain binding activity and ionotropic glutamate receptor binding activity. Involved in intracellular protein transport; positive regulation of protein catabolic process; and positive regulatio... |
Does Knockout of SFRP2 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 0 | 180 | Knockout | SFRP2 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: SFRP2 (secreted frizzled related protein 2)
Type: protein-coding
Summary: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene ... |
Does Knockout of RPF1 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 897 | Knockout | RPF1 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: RPF1 (ribosome production factor 1 homolog)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: maturation ... |
Does Knockout of TNFAIP8L2 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 305 | Knockout | TNFAIP8L2 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: TNFAIP8L2 (TNF alpha induced protein 8 like 2)
Type: protein-coding
Summary: Predicted to be involved in negative regulation of T cell activation and negative regulation of inflammatory response. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gen... |
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