prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of AFDN in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | AFDN | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: AFDN (afadin, adherens junction formation factor)
Type: protein-coding
Summary: This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, in... |
Does Knockout of LCE6A in Cancer Cell Line causally result in cell proliferation? | 0 | 948 | Knockout | LCE6A | cell proliferation | Cancer Cell Line | Gene: LCE6A (late cornified envelope 6A)
Type: protein-coding
Summary: Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways: Developmental Biology, Formation of the cornified envelope, Keratinization
UniProt:... |
Does Knockout of SH3BP5L in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | SH3BP5L | cell proliferation | Colonic Cancer Cell Line | Gene: SH3BP5L (SH3 binding domain protein 5 like)
Type: protein-coding
Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction and negative regulation of protein tyrosine kinase activity. Predicted to be active in cytoplasm. [provided by... |
Does Knockout of DMTN in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | DMTN | cell proliferation | Monocytic Leukemia Cell Line | Gene: DMTN (dematin actin binding protein)
Type: protein-coding
Summary: The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-d... |
Does Activation of SH2B3 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | SH2B3 | protein/peptide accumulation | T cell | Gene: SH2B3 (SH2B adaptor protein 3)
Type: protein-coding
Summary: This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and p... |
Does Knockout of POLE3 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | POLE3 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: POLE3 (DNA polymerase epsilon 3, accessory subunit)
Type: protein-coding
Summary: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transc... |
Does Knockout of INS in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | INS | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: INS (insulin)
Type: protein-coding
Summary: This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A ... |
Does Knockout of ABCF1 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | ABCF1 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: ABCF1 (ATP binding cassette subfamily F member 1)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided int... |
Does Knockout of MAPK11 in Lymphoma Cell Line causally result in cell proliferation? | 0 | 646 | Knockout | MAPK11 | cell proliferation | Lymphoma Cell Line | Gene: MAPK11 (mitogen-activated protein kinase 11)
Type: protein-coding
Summary: This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional ... |
Does Knockout of OR2A12 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | OR2A12 | cell proliferation | Monocytic Leukemia Cell Line | Gene: OR2A12 (olfactory receptor family 2 subfamily A member 12)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of RNF4 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | RNF4 | cell proliferation | Medulloblastoma Cell Line | Gene: RNF4 (ring finger protein 4)
Type: protein-coding
Summary: The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcriptio... |
Does Knockout of PRSS38 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,459 | Knockout | PRSS38 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: PRSS38 (serine protease 38)
Type: protein-coding
Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: proteolysis; ... |
Does Knockout of TRPM7 in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | TRPM7 | cell proliferation | Breast Cancer Cell Line | Gene: TRPM7 (transient receptor potential cation channel subfamily M member 7)
Type: protein-coding
Summary: This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase... |
Does Knockout of DPP6 in Lung Cancer Cell Line causally result in response to virus? | 1 | 1,433 | Knockout | DPP6 | response to virus | Lung Cancer Cell Line | Gene: DPP6 (dipeptidyl peptidase like 6)
Type: protein-coding
Summary: This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine resid... |
Does Knockout of TOMM40 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | TOMM40 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: TOMM40 (translocase of outer mitochondrial membrane 40)
Type: protein-coding
Summary: The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential fo... |
Does Knockout of ZNF821 in Ovarian Cancer Cell Line causally result in cell proliferation? | 0 | 699 | Knockout | ZNF821 | cell proliferation | Ovarian Cancer Cell Line | Gene: ZNF821 (zinc finger protein 821)
Type: protein-coding
Summary: This gene encodes a protein with two C2H2 zinc finger motifs and a score-and-three (23)-amino acid peptide repeat (STPR) domain. The STPR domain of the encoded protein binds to double stranded DNA and may also contain a nuclear localiz... |
Does Knockout of ZNF665 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 839 | Knockout | ZNF665 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: ZNF665 (zinc finger protein 665)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RN... |
Does Knockout of KIN in acute lymphoblastic leukemia cell line causally result in cell proliferation? | 1 | 1,957 | Knockout | KIN | cell proliferation | acute lymphoblastic leukemia cell line | Gene: KIN (Kin17 DNA and RNA binding protein)
Type: protein-coding
Summary: The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of t... |
Does Knockout of TOP2A in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | TOP2A | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: TOP2A (DNA topoisomerase II alpha)
Type: protein-coding
Summary: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the r... |
Does Knockout of ERCC2 in T-lymphoma cell line causally result in cell proliferation? | 1 | 478 | Knockout | ERCC2 | cell proliferation | T-lymphoma cell line | Gene: ERCC2 (ERCC excision repair 2, TFIIH core complex helicase subunit)
Type: protein-coding
Summary: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral membe... |
Does Knockout of RAB4B in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | RAB4B | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: RAB4B (RAB4B, member RAS oncogene family)
Type: protein-coding
Summary: RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).[supplied by OMIM, Aug 2009]
Gene Ontology: BP: D-glucose... |
Does Knockout of PCBD1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | PCBD1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1)
Type: protein-coding
Summary: This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. ... |
Does Knockout of TOP3A in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | TOP3A | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: TOP3A (DNA topoisomerase III alpha)
Type: protein-coding
Summary: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strand... |
Does Knockout of DDA1 in Multiple Myeloma Cell Line causally result in cell proliferation? | 1 | 816 | Knockout | DDA1 | cell proliferation | Multiple Myeloma Cell Line | Gene: DDA1 (DET1 and DDB1 associated 1)
Type: protein-coding
Summary: Involved in protein polyubiquitination. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: positive regulation of proteasomal ubiquitin-dependent protein cat... |
Does Knockout of VCP in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | VCP | cell proliferation | Bladder Carcinoma | Gene: VCP (valosin containing protein)
Type: protein-coding
Summary: This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF... |
Does Knockout of NPR3 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | NPR3 | cell proliferation | Glioblastoma Cell Line | Gene: NPR3 (natriuretic peptide receptor 3)
Type: protein-coding
Summary: This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth proc... |
Does Knockout of CYP2R1 in Glioblastoma Cell Line causally result in response to chemicals? | 1 | 2,344 | Knockout | CYP2R1 | response to chemicals | Glioblastoma Cell Line | Gene: CYP2R1 (cytochrome P450 family 2 subfamily R member 1)
Type: protein-coding
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, ste... |
Does Knockout of TOMM40 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | TOMM40 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: TOMM40 (translocase of outer mitochondrial membrane 40)
Type: protein-coding
Summary: The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential fo... |
Does Knockout of MICOS10 in Hepatoma Cell Line causally result in response to virus? | 1 | 2,437 | Knockout | MICOS10 | response to virus | Hepatoma Cell Line | Gene: MICOS10 (mitochondrial contact site and cristae organizing system subunit 10)
Type: protein-coding
Summary: Predicted to be involved in inner mitochondrial membrane organization. Located in mitochondrion. Part of MIB complex; MICOS complex; and SAM complex. [provided by Alliance of Genome Resource... |
Does Knockout of KRT38 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | KRT38 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: KRT38 (keratin 38)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chro... |
Does Knockout of RAB35 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 758 | Knockout | RAB35 | cell proliferation | Endometrial Cancer Cell Line | Gene: RAB35 (RAB35, member RAS oncogene family)
Type: protein-coding
Summary: Enables GTPase activity; guanyl ribonucleotide binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including endosomal transport; plasma membrane to endosome transport; ... |
Does Knockout of IRF2BPL in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 1,311 | Knockout | IRF2BPL | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: IRF2BPL (interferon regulatory factor 2 binding protein like)
Type: protein-coding
Summary: This gene encodes a transcription factor that may play a role in regulating female reproductive function. [provided by RefSeq, Jun 2012].
Gene Ontology: BP: development of secondary female sexual c... |
Does Knockout of CRIM1 in Breast Cancer Cell Line causally result in cell proliferation? | 0 | 235 | Knockout | CRIM1 | cell proliferation | Breast Cancer Cell Line | Gene: CRIM1 (cysteine rich transmembrane BMP regulator 1)
Type: protein-coding
Summary: This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions wi... |
Does Knockout of ENDOV in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 69 | Knockout | ENDOV | cell proliferation | Monocytic Leukemia Cell Line | Gene: ENDOV (endonuclease V)
Type: protein-coding
Summary: Enables DNA binding activity; endoribonuclease activity, producing 5'-phosphomonoesters; and single-stranded RNA binding activity. Predicted to be involved in DNA repair. Located in cytoplasmic stress granule and nucleolus. [provided by Alliance... |
Does Knockout of DDX21 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | DDX21 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: DDX21 (DExD-box helicase 21)
Type: protein-coding
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiatio... |
Does Knockout of LTV1 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,340 | Knockout | LTV1 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: LTV1 (LTV1 ribosome biogenesis factor)
Type: protein-coding
Summary: Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: ... |
Does Knockout of COA3 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,789 | Knockout | COA3 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: COA3 (cytochrome c oxidase assembly factor 3)
Type: protein-coding
Summary: This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase functi... |
Does Knockout of ERI2 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | ERI2 | cell proliferation | Cancer Cell Line | Gene: ERI2 (ERI1 exoribonuclease family member 2)
Type: protein-coding
Summary: Predicted to enable 3'-5'-exoribonuclease activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). [provided by A... |
Does Knockout of SRP54 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 865 | Knockout | SRP54 | cell proliferation | Colonic Cancer Cell Line | Gene: SRP54 (signal recognition particle 54)
Type: protein-coding
Summary: Enables several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and guanyl ribonucleotide binding activity. Contributes to GTPase activity. Involved in granulocyte differentiat... |
Does Knockout of EXOSC4 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | EXOSC4 | cell proliferation | Melanoma Cell Line | Gene: EXOSC4 (exosome component 4)
Type: protein-coding
Summary: Enables mRNA 3'-UTR AU-rich region binding activity. Involved in nucleic acid metabolic process and positive regulation of cell growth. Acts upstream of or within defense response to virus. Located in cytosol; nucleoplasm; and transcriptio... |
Does Activation of RP2 in T cell causally result in protein/peptide accumulation? | 1 | 2,426 | Activation | RP2 | protein/peptide accumulation | T cell | Gene: RP2 (RP2 activator of ARL3 GTPase)
Type: protein-coding
Summary: The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal de... |
Does Knockout of SH2D3C in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | SH2D3C | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: SH2D3C (SH2 domain containing 3C)
Type: protein-coding
Summary: This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which a... |
Does Knockout of POLRMT in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,789 | Knockout | POLRMT | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: POLRMT (RNA polymerase mitochondrial)
Type: protein-coding
Summary: This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Altho... |
Does Knockout of KANK2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 69 | Knockout | KANK2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: KANK2 (KN motif and ankyrin repeat domains 2)
Type: protein-coding
Summary: This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestr... |
Does Knockout of EMC3 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | EMC3 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: EMC3 (ER membrane protein complex subunit 3)
Type: protein-coding
Summary: Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Is integral component of en... |
Does Knockout of USP17L4 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | USP17L4 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: USP17L4 (ubiquitin specific peptidase 17 like family member 4)
Type: protein-coding
Summary: Predicted to enable cysteine-type endopeptidase activity and thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination and regulation of apoptotic process. Predicted to be locate... |
Does Activation of RABEP1 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | RABEP1 | protein/peptide accumulation | T cell | Gene: RABEP1 (rabaptin, RAB GTPase binding effector protein 1)
Type: protein-coding
Summary: Enables protein domain specific binding activity and protein homodimerization activity. Involved in vesicle-mediated transport. Located in endocytic vesicle and endosome. Part of protein-containing complex. [pro... |
Does Knockout of STIM2 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 1,813 | Knockout | STIM2 | cell proliferation | Medulloblastoma Cell Line | Gene: STIM2 (stromal interaction molecule 2)
Type: protein-coding
Summary: This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in t... |
Does Knockout of MOG in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | MOG | cell proliferation | Glioblastoma Cell Line | Gene: MOG (myelin oligodendrocyte glycoprotein)
Type: protein-coding
Summary: The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated dem... |
Does Knockout of RPL38 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | RPL38 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: RPL38 (ribosomal protein L38)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Activation of FKBP14 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | FKBP14 | protein/peptide accumulation | T cell | Gene: FKBP14 (FKBP prolyl isomerase 14)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the FK506-binding protein family of peptidyl-prolyl cis-trans isomerases. The encoded protein is found in the lumen of the endoplasmic reticulum, where it is thought to accelerate protei... |
Does Knockout of ZNF354C in Lung Cancer Cell Line causally result in response to virus? | 1 | 1,433 | Knockout | ZNF354C | response to virus | Lung Cancer Cell Line | Gene: ZNF354C (zinc finger protein 354C)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by ... |
Does Knockout of C6orf52 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,430 | Knockout | C6orf52 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: C6orf52 (chromosome 6 open reading frame 52)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q5T4I8
Entrez ID: 347744 |
Does Knockout of GGTLC2 in Prostate Cancer Cell Line causally result in cell proliferation? | 1 | 843 | Knockout | GGTLC2 | cell proliferation | Prostate Cancer Cell Line | Gene: GGTLC2 (gamma-glutamyltransferase light chain 2)
Type: protein-coding
Summary: This gene encodes a protein related to enzymes that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides. Unlike similar proteins, the encoded protein contains only the light chain portion and may not ... |
Does Knockout of CFDP1 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 334 | Knockout | CFDP1 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: CFDP1 (craniofacial development protein 1)
Type: protein-coding
Summary: Predicted to act upstream of or within several processes, including cell adhesion; negative regulation of fibroblast apoptotic process; and regulation of cell shape. Predicted to be located in kinetochore. [provided by Allian... |
Does Knockout of ZNF442 in Breast Cancer Cell Line causally result in cell proliferation? | 1 | 235 | Knockout | ZNF442 | cell proliferation | Breast Cancer Cell Line | Gene: ZNF442 (zinc finger protein 442)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcrip... |
Does Knockout of NEURL1 in Neuroblastoma Cell Line causally result in cell proliferation? | 0 | 824 | Knockout | NEURL1 | cell proliferation | Neuroblastoma Cell Line | Gene: NEURL1 (neuralized E3 ubiquitin protein ligase 1)
Type: protein-coding
Summary: Predicted to enable translation factor activity, non-nucleic acid binding and ubiquitin protein ligase activity. Involved in negative regulation of Notch signaling pathway; negative regulation of cell population prolif... |
Does Knockout of POU2F1 in Lung Cancer Cell Line causally result in cell proliferation? | 1 | 674 | Knockout | POU2F1 | cell proliferation | Lung Cancer Cell Line | Gene: POU2F1 (POU class 2 homeobox 1)
Type: protein-coding
Summary: The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region nece... |
Does Knockout of PRELID1 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | PRELID1 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: PRELID1 (PRELI domain containing 1)
Type: protein-coding
Summary: This gene encodes a member of the late embryogenesis abundant motif-containing protein family. The encoded protein is localized to mitochondria and may function as a cytoprotectant by regulating cell death and differentiation. Alter... |
Does Knockout of POU4F1 in Prostate Cancer Cell Line causally result in cell proliferation? | 0 | 843 | Knockout | POU4F1 | cell proliferation | Prostate Cancer Cell Line | Gene: POU4F1 (POU class 4 homeobox 1)
Type: protein-coding
Summary: This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote ... |
Does Knockout of ADSL in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | ADSL | cell proliferation | Monocytic Leukemia Cell Line | Gene: ADSL (adenylosuccinate lyase)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylamin... |
Does Knockout of CDK1 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | CDK1 | cell proliferation | Colorectal Cancer Cell Line | Gene: CDK1 (cyclin dependent kinase 1)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G2/M ... |
Does Knockout of OSGEP in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | OSGEP | cell proliferation | Endometrial Cancer Cell Line | Gene: OSGEP (O-sialoglycoprotein endopeptidase)
Type: protein-coding
Summary: Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Involved in tRNA threonylcarbamoyladenosine modification. Located in cytoplasm; nuclear speck; and plasma membrane. Part of ... |
Does Knockout of IPO11 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | IPO11 | cell proliferation | Gastric Cancer Cell Line | Gene: IPO11 (importin 11)
Type: protein-coding
Summary: Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied ... |
Does Knockout of SPINT1 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | SPINT1 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: SPINT1 (serine peptidase inhibitor, Kunitz type 1)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the prot... |
Does Knockout of S100A2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,658 | Knockout | S100A2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: S100A2 (S100 calcium binding protein A2)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the ... |
Does Knockout of CCDC38 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,329 | Knockout | CCDC38 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: CCDC38 (coiled-coil domain containing 38)
Type: protein-coding
Summary: Located in centrosome. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: acrosome assembly, cell differentiation, chromatin organization, intraciliary anterograde transport, sperm flagellum assem... |
Does Knockout of CCNDBP1 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | CCNDBP1 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: CCNDBP1 (cyclin D1 binding protein 1)
Type: protein-coding
Summary: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfecti... |
Does Knockout of NDC80 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,114 | Knockout | NDC80 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: NDC80 (NDC80 kinetochore complex component)
Type: protein-coding
Summary: This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the compl... |
Does Activation of TRAIP in Hepatoma Cell Line causally result in response to virus? | 0 | 1,210 | Activation | TRAIP | response to virus | Hepatoma Cell Line | Gene: TRAIP (TRAF interacting protein)
Type: protein-coding
Summary: This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosi... |
Does Knockout of C8B in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 906 | Knockout | C8B | cell proliferation | Glioblastoma Cell Line | Gene: C8B (complement C8 beta chain)
Type: protein-coding
Summary: This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane... |
Does Knockout of ACTR8 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | ACTR8 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: ACTR8 (actin related protein 8)
Type: protein-coding
Summary: Predicted to enable ATP binding activity. Predicted to be involved in chromatin remodeling; double-strand break repair; and regulation of transcription, DNA-templated. Located in centrosome and nucleoplasm. Part of Ino80 complex. [provi... |
Does Knockout of TRPM7 in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | TRPM7 | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: TRPM7 (transient receptor potential cation channel subfamily M member 7)
Type: protein-coding
Summary: This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase... |
Does Knockout of MIIP in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | MIIP | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: MIIP (migration and invasion inhibitory protein)
Type: protein-coding
Summary: This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cel... |
Does Knockout of DCTN6 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,789 | Knockout | DCTN6 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: DCTN6 (dynactin subunit 6)
Type: protein-coding
Summary: The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homol... |
Does Knockout of DTNB in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,329 | Knockout | DTNB | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: DTNB (dystrobrevin beta)
Type: protein-coding
Summary: This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and d... |
Does Knockout of NOXRED1 in Cancer Cell Line causally result in cell proliferation? | 0 | 193 | Knockout | NOXRED1 | cell proliferation | Cancer Cell Line | Gene: NOXRED1 (NADP dependent oxidoreductase domain containing 1)
Type: protein-coding
Summary: Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: L-p... |
Does Knockout of CRYBG3 in Retinal Pigment Epithelium Cell Line causally result in response to chemicals? | 0 | 1,339 | Knockout | CRYBG3 | response to chemicals | Retinal Pigment Epithelium Cell Line | Gene: CRYBG3 (crystallin beta-gamma domain containing 3)
Type: protein-coding
Summary: Enables protein kinase A binding activity. Predicted to be involved in lens development in camera-type eye and visual perception. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022... |
Does Knockout of CALCB in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 1,311 | Knockout | CALCB | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: CALCB (calcitonin related polypeptide beta)
Type: protein-coding
Summary: Predicted to enable calcitonin receptor binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of cytosolic calcium ion concentration. Predicted... |
Does Knockout of ATE1 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | ATE1 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: ATE1 (arginyltransferase 1)
Type: protein-coding
Summary: This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets protein... |
Does Knockout of OR2T1 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 1,246 | Knockout | OR2T1 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: OR2T1 (olfactory receptor family 2 subfamily T member 1)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protei... |
Does Knockout of LTBP1 in Multiple Myeloma Cell Line causally result in cell proliferation? | 0 | 816 | Knockout | LTBP1 | cell proliferation | Multiple Myeloma Cell Line | Gene: LTBP1 (latent transforming growth factor beta binding protein 1)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated pro... |
Does Knockout of ISG20L2 in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | ISG20L2 | cell proliferation | Cancer Cell Line | Gene: ISG20L2 (interferon stimulated exonuclease gene 20 like 2)
Type: protein-coding
Summary: This gene encodes a 3'-5' exoribonuclease that may be involved in the processing of the 12S pre-rRNA. Pseudogenes have been identified on chromosomes 6 and 11. [provided by RefSeq, Dec 2014].
Gene Ont... |
Does Knockout of FAM218A in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | FAM218A | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: FAM218A (family with sequence similarity 218 member A)
Type: ncRNA
Summary: family with sequence similarity 218 member A
Gene Ontology:
Pathways:
UniProt:
Entrez ID: 152756 |
Does Knockout of CELF1 in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | CELF1 | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: CELF1 (CUGBP Elav-like family member 1)
Type: protein-coding
Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this pro... |
Does Knockout of GEMIN7 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | GEMIN7 | cell proliferation | Endometrial Cancer Cell Line | Gene: GEMIN7 (gem nuclear organelle associated protein 7)
Type: protein-coding
Summary: The protein encoded by this gene is a component of the core SMN complex, which is required for pre-mRNA splicing in the nucleus. The encoded protein is found in the nucleoplasm, in nuclear 'gems' (Gemini of Cajal bod... |
Does Knockout of SLC7A5 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | SLC7A5 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SLC7A5 (solute carrier family 7 member 5)
Type: protein-coding
Summary: Enables L-leucine transmembrane transporter activity; L-tryptophan transmembrane transporter activity; and thyroid hormone transmembrane transporter activity. Involved in carboxylic acid transport; thyroid hormone transport; a... |
Does Knockout of MIR3646 in Glioblastoma Cell Line causally result in response to chemicals? | 1 | 2,344 | Knockout | MIR3646 | response to chemicals | Glioblastoma Cell Line | Gene: MIR3646 (microRNA 3646)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase... |
Does Knockout of EMSY in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 951 | Knockout | EMSY | cell proliferation | Colonic Cancer Cell Line | Gene: EMSY (EMSY transcriptional repressor, BRCA2 interacting)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in DNA repair; chromatin organization; and regulation of transcription, DNA-templated. Located in nucleoplasm. [provided by Allian... |
Does Knockout of USP36 in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 734 | Knockout | USP36 | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: USP36 (ubiquitin specific peptidase 36)
Type: protein-coding
Summary: This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitina... |
Does Knockout of B3GNT7 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | B3GNT7 | response to virus | Hepatoma Cell Line | Gene: B3GNT7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7)
Type: protein-coding
Summary: Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process. Predicted to be integral component of membrane. Predicted to be acti... |
Does Knockout of AASDHPPT in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | AASDHPPT | response to virus | Hepatoma Cell Line | Gene: AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase)
Type: protein-coding
Summary: The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of... |
Does Knockout of PEBP1 in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | PEBP1 | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: PEBP1 (phosphatidylethanolamine binding protein 1)
Type: protein-coding
Summary: This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kina... |
Does Knockout of UTP20 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 287 | Knockout | UTP20 | cell proliferation | Endometrial Cancer Cell Line | Gene: UTP20 (UTP20 small subunit processome component)
Type: protein-coding
Summary: UTP20 is a component of the U3 small nucleolar RNA (snoRNA) (SNORD3A; MIM 180710) protein complex (U3 snoRNP) and is involved in 18S rRNA processing (Wang et al., 2007 [PubMed 17498821]).[supplied by OMIM, Jun 2009].
... |
Does Knockout of DDX47 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 865 | Knockout | DDX47 | cell proliferation | Colonic Cancer Cell Line | Gene: DDX47 (DEAD-box helicase 47)
Type: protein-coding
Summary: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alterati... |
Does Knockout of WDR82 in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | WDR82 | cell proliferation | Ewing's Sarcoma Cell Line | Gene: WDR82 (WD repeat domain 82)
Type: protein-coding
Summary: TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010].
... |
Does Knockout of ORC5 in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | ORC5 | cell proliferation | Renal Cancer Cell Line | Gene: ORC5 (origin recognition complex subunit 5)
Type: protein-coding
Summary: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to ori... |
Does Knockout of KCTD21 in Embryonic Kidney Cell Line causally result in protein/peptide accumulation? | 0 | 1,461 | Knockout | KCTD21 | protein/peptide accumulation | Embryonic Kidney Cell Line | Gene: KCTD21 (potassium channel tetramerization domain containing 21)
Type: protein-coding
Summary: Enables cullin family protein binding activity; histone deacetylase binding activity; and identical protein binding activity. Involved in negative regulation of smoothened signaling pathway and ubiquitin-... |
Does Knockout of PLAGL2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | PLAGL2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: PLAGL2 (PLAG1 like zinc finger 2)
Type: protein-coding
Summary: Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. [provided by RefSeq, Jul 2008].
Gene Ontology: BP: chylomicron assembly, lipid metabolic process, positive regulation of intrinsic apop... |
Does Knockout of RPL31 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | RPL31 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RPL31 (ribosomal protein L31)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
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