prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of WASF1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | WASF1 | cell proliferation | Colonic Cancer Cell Line | Gene: WASF1 (WASP family member 1)
Type: protein-coding
Summary: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It h... |
Does Knockout of CACNA1H in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | CACNA1H | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: CACNA1H (calcium voltage-gated channel subunit alpha1 H)
Type: protein-coding
Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polari... |
Does Knockout of SRSF2 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | SRSF2 | cell proliferation | Gastric Cancer Cell Line | Gene: SRSF2 (serine and arginine rich splicing factor 2)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM... |
Does Knockout of RAPGEF2 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,032 | Knockout | RAPGEF2 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: RAPGEF2 (Rap guanine nucleotide exchange factor 2)
Type: protein-coding
Summary: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange fa... |
Does Knockout of PCP4L1 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | PCP4L1 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: PCP4L1 (Purkinje cell protein 4 like 1)
Type: protein-coding
Summary: Purkinje cell protein 4 like 1
Gene Ontology:
Pathways:
UniProt: A6NKN8
Entrez ID: 654790 |
Does Knockout of TRAPPC3 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | TRAPPC3 | cell proliferation | Colonic Cancer Cell Line | Gene: TRAPPC3 (trafficking protein particle complex subunit 3)
Type: protein-coding
Summary: This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the end... |
Does Knockout of MCC in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | MCC | cell proliferation | Medulloblastoma Cell Line | Gene: MCC (MCC regulator of Wnt signaling pathway)
Type: protein-coding
Summary: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and m... |
Does Knockout of OSBPL11 in Prostate Cancer Cell Line causally result in response to chemicals? | 1 | 2,109 | Knockout | OSBPL11 | response to chemicals | Prostate Cancer Cell Line | Gene: OSBPL11 (oxysterol binding protein like 11)
Type: protein-coding
Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conse... |
Does Knockout of SLC38A9 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | SLC38A9 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: SLC38A9 (solute carrier family 38 member 9)
Type: protein-coding
Summary: Enables L-arginine transmembrane transporter activity and L-leucine transmembrane transporter activity. Involved in amino acid transmembrane transport; cellular response to amino acid stimulus; and positive regulation of TOR... |
Does Knockout of KTI12 in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | KTI12 | cell proliferation | Renal Cancer Cell Line | Gene: KTI12 (KTI12 chromatin associated homolog)
Type: protein-coding
Summary: Predicted to enable ATP binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and tRNA wobble uridine modification. [provided by Alliance of Genome Resources, Apr 2022]
Gene O... |
Does Activation of EDN1 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | EDN1 | protein/peptide accumulation | T cell | Gene: EDN1 (endothelin 1)
Type: protein-coding
Summary: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the ... |
Does Knockout of RNF4 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | RNF4 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RNF4 (ring finger protein 4)
Type: protein-coding
Summary: The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcriptio... |
Does Knockout of KCTD20 in Cancer Cell Line causally result in cell proliferation? | 0 | 948 | Knockout | KCTD20 | cell proliferation | Cancer Cell Line | Gene: KCTD20 (potassium channel tetramerization domain containing 20)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in positive regulation of phosphorylation. Predicted to be integral component of membrane. Predicted to be active in cytopl... |
Does Knockout of LGALS12 in Melanoma Cell Line causally result in response to chemicals? | 1 | 1,940 | Knockout | LGALS12 | response to chemicals | Melanoma Cell Line | Gene: LGALS12 (galectin 12)
Type: protein-coding
Summary: This gene encodes a member of the galectin superfamily, a group of beta-galactoside-binding proteins with conserved carbohydrate recognition domains. The related mouse protein is a primary regulator of the early stages of adipose tissue developme... |
Does Knockout of INTS13 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | INTS13 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: INTS13 (integrator complex subunit 13)
Type: protein-coding
Summary: Involved in regulation of mitotic cell cycle. Acts upstream of or within centrosome localization; mitotic spindle organization; and protein localization to nuclear envelope. Located in cytoplasm and nuclear body. [provided by All... |
Does Knockout of RPS29 in T-lymphoma cell line causally result in cell proliferation? | 1 | 478 | Knockout | RPS29 | cell proliferation | T-lymphoma cell line | Gene: RPS29 (ribosomal protein S29)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of CACNA1G in Colonic Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,736 | Knockout | CACNA1G | response to chemicals | Colonic Adenocarcinoma Cell Line | Gene: CACNA1G (calcium voltage-gated channel subunit alpha1 G)
Type: protein-coding
Summary: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmi... |
Does Knockout of CCT6A in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | CCT6A | cell proliferation | Gastric Cancer Cell Line | Gene: CCT6A (chaperonin containing TCP1 subunit 6A)
Type: protein-coding
Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, ... |
Does Inhibition of ZFPM2 in Mammary Epithelial Cell Line causally result in cell proliferation? | 0 | 2,248 | Inhibition | ZFPM2 | cell proliferation | Mammary Epithelial Cell Line | Gene: ZFPM2 (zinc finger protein, FOG family member 2)
Type: protein-coding
Summary: The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of h... |
Does Knockout of CARNS1 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 758 | Knockout | CARNS1 | cell proliferation | Endometrial Cancer Cell Line | Gene: CARNS1 (carnosine synthase 1)
Type: protein-coding
Summary: CARNS1 (EC 6.3.2.11), a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the centra... |
Does Knockout of HYOU1 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | HYOU1 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: HYOU1 (hypoxia up-regulated 1)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accu... |
Does Knockout of SMIM10 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,447 | Knockout | SMIM10 | response to virus | Hepatoma Cell Line | Gene: SMIM10 (small integral membrane protein 10)
Type: protein-coding
Summary: Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
UniProt: Q96HG1
Entrez ID: 644538 |
Does Knockout of RPA3 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 865 | Knockout | RPA3 | cell proliferation | Colonic Cancer Cell Line | Gene: RPA3 (replication protein A3)
Type: protein-coding
Summary: Enables damaged DNA binding activity and single-stranded DNA binding activity. Involved in DNA repair and DNA replication. Part of DNA replication factor A complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontolo... |
Does Knockout of SPRY4 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 787 | Knockout | SPRY4 | cell proliferation | Gastric Cancer Cell Line | Gene: SPRY4 (sprouty RTK signaling antagonist 4)
Type: protein-coding
Summary: This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein... |
Does Knockout of OAF in Melanoma Cell Line causally result in response to chemicals? | 1 | 1,940 | Knockout | OAF | response to chemicals | Melanoma Cell Line | Gene: OAF (out at first homolog)
Type: protein-coding
Summary: out at first homolog
Gene Ontology:
Pathways:
UniProt: Q86UD1
Entrez ID: 220323 |
Does Knockout of ARPP19 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | ARPP19 | cell proliferation | Gastric Cancer Cell Line | Gene: ARPP19 (cAMP regulated phosphoprotein 19)
Type: protein-coding
Summary: The 19-kD cAMP-regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase-2A (PP2A; see MIM 176915) (summary by Gharbi-Ayachi et al., 2010 [PubMed 21164014]).[supplied by OMIM, Feb 2011].
... |
Does Knockout of ZNF671 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | ZNF671 | cell proliferation | Glioblastoma Cell Line | Gene: ZNF671 (zinc finger protein 671)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted t... |
Does Knockout of HERC6 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | HERC6 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: HERC6 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 6)
Type: protein-coding
Summary: HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted... |
Does Knockout of FAM234A in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 206 | Knockout | FAM234A | cell proliferation | Monocytic Leukemia Cell Line | Gene: FAM234A (family with sequence similarity 234 member A)
Type: protein-coding
Summary: Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: cell surface, extracellular exosome, membrane
Pathways:
UniProt: Q9H0X4
Entrez I... |
Does Knockout of MAP4K1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 951 | Knockout | MAP4K1 | cell proliferation | Colonic Cancer Cell Line | Gene: MAP4K1 (mitogen-activated protein kinase kinase kinase kinase 1)
Type: protein-coding
Summary: Enables ATP binding activity and MAP kinase kinase kinase kinase activity. Involved in several processes, including JNK cascade; cellular response to phorbol 13-acetate 12-myristate; and protein phosphor... |
Does Knockout of DNAJC7 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 787 | Knockout | DNAJC7 | cell proliferation | Gastric Cancer Cell Line | Gene: DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7)
Type: protein-coding
Summary: This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chap... |
Does Knockout of DCAF15 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | DCAF15 | cell proliferation | Monocytic Leukemia Cell Line | Gene: DCAF15 (DDB1 and CUL4 associated factor 15)
Type: protein-coding
Summary: Enables small molecule binding activity. Involved in protein polyubiquitination and regulation of natural killer cell activation. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr ... |
Does Knockout of SPDL1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 206 | Knockout | SPDL1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SPDL1 (spindle apparatus coiled-coil protein 1)
Type: protein-coding
Summary: This gene encodes a coiled-coil domain-containing protein that functions in mitotic spindle formation and chromosome segregation. The encoded protein plays a role in coordinating microtubule attachment by promoting recru... |
Does Knockout of KISS1R in Astrocytoma Cell Line causally result in cell proliferation? | 0 | 904 | Knockout | KISS1R | cell proliferation | Astrocytoma Cell Line | Gene: KISS1R (KISS1 receptor)
Type: protein-coding
Summary: The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regu... |
Does Knockout of LCLAT1 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | LCLAT1 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: LCLAT1 (lysocardiolipin acyltransferase 1)
Type: protein-coding
Summary: Enables 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Located in cytosol and endoplasmic reticulum. [provided by Alliance of Genome Resources, A... |
Does Knockout of LAMTOR4 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 69 | Knockout | LAMTOR4 | cell proliferation | Monocytic Leukemia Cell Line | Gene: LAMTOR4 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 4)
Type: protein-coding
Summary: Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cellular response to amino acid stimulus; positive regulation of TO... |
Does Knockout of RASGRF1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 69 | Knockout | RASGRF1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1)
Type: protein-coding
Summary: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimu... |
Does Knockout of FRMPD4 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | FRMPD4 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: FRMPD4 (FERM and PDZ domain containing 4)
Type: protein-coding
Summary: This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is requi... |
Does Knockout of CDK2 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | CDK2 | cell proliferation | Glioblastoma Cell Line | Gene: CDK2 (cyclin dependent kinase 2)
Type: protein-coding
Summary: This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progress... |
Does Knockout of FAM43B in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | FAM43B | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: FAM43B (family with sequence similarity 43 member B)
Type: protein-coding
Summary: family with sequence similarity 43 member B
Gene Ontology:
Pathways:
UniProt: Q6ZT52
Entrez ID: 163933 |
Does Knockout of PCM1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | PCM1 | cell proliferation | Melanoma Cell Line | Gene: PCM1 (pericentriolar material 1)
Type: protein-coding
Summary: The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several ce... |
Does Knockout of CDH17 in Colorectal Cancer Cell Line causally result in response to chemicals? | 0 | 1,414 | Knockout | CDH17 | response to chemicals | Colorectal Cancer Cell Line | Gene: CDH17 (cadherin 17)
Type: protein-coding
Summary: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane ... |
Does Knockout of RAB7A in Huh-7 Cell causally result in response to virus? | 1 | 1,382 | Knockout | RAB7A | response to virus | Huh-7 Cell | Gene: RAB7A (RAB7A, member RAS oncogene family)
Type: protein-coding
Summary: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB... |
Does Knockout of RBSN in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | RBSN | cell proliferation | Gastric Cancer Cell Line | Gene: RBSN (rabenosyn, RAB effector)
Type: protein-coding
Summary: This gene encodes a protein that belongs to the FYVE zinc finger family of proteins. The encoded protein interacts with Ras-related proteins that regulate membrane trafficking. A missense mutation in this gene is associated with a defect... |
Does Knockout of RPS9 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 865 | Knockout | RPS9 | cell proliferation | Colonic Cancer Cell Line | Gene: RPS9 (ribosomal protein S9)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ... |
Does Knockout of FCMR in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,352 | Knockout | FCMR | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: FCMR (Fc mu receptor)
Type: protein-coding
Summary: Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed ... |
Does Knockout of HOXC11 in Colorectal Cancer Cell Line causally result in cell proliferation? | 0 | 783 | Knockout | HOXC11 | cell proliferation | Colorectal Cancer Cell Line | Gene: HOXC11 (homeobox C11)
Type: protein-coding
Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gen... |
Does Knockout of AP1B1 in Medulloblastoma Cell Line causally result in cell proliferation? | 0 | 408 | Knockout | AP1B1 | cell proliferation | Medulloblastoma Cell Line | Gene: AP1B1 (adaptor related protein complex 1 subunit beta 1)
Type: protein-coding
Summary: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signa... |
Does Knockout of AGAP4 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 149 | Knockout | AGAP4 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: AGAP4 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 4)
Type: protein-coding
Summary: Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be involved in regulation of catalytic activity. Predicted to be active in nucleus. [provided by Alliance of Ge... |
Does Knockout of MINDY4 in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | MINDY4 | response to virus | Cervical Adenocarcinoma Cell Line | Gene: MINDY4 (MINDY lysine 48 deubiquitinase 4)
Type: protein-coding
Summary: Predicted to enable Lys48-specific deubiquitinase activity. Predicted to be involved in protein K48-linked deubiquitination. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: protein K48-linked d... |
Does Knockout of SLC30A6 in Monocytic Leukemia Cell Line causally result in response to chemicals? | 0 | 1,978 | Knockout | SLC30A6 | response to chemicals | Monocytic Leukemia Cell Line | Gene: SLC30A6 (solute carrier family 30 member 6)
Type: protein-coding
Summary: This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer's dis... |
Does Knockout of DEFB116 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | DEFB116 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: DEFB116 (defensin beta 116)
Type: protein-coding
Summary: Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. A... |
Does Knockout of XPO1 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | XPO1 | cell proliferation | Gastric Cancer Cell Line | Gene: XPO1 (exportin 1)
Type: protein-coding
Summary: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several ce... |
Does Knockout of RPL21 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | RPL21 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: RPL21 (ribosomal protein L21)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of SPATA31A7 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,576 | Knockout | SPATA31A7 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: SPATA31A7 (SPATA31 subfamily A member 7)
Type: protein-coding
Summary: Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: cell differentiation, sperma... |
Does Knockout of PCCA in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | PCCA | cell proliferation | T-lymphoma cell line | Gene: PCCA (propionyl-CoA carboxylase subunit alpha)
Type: protein-coding
Summary: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding ... |
Does Knockout of DDX27 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | DDX27 | cell proliferation | Colorectal Cancer Cell Line | Gene: DDX27 (DEAD-box helicase 27)
Type: protein-coding
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiatio... |
Does Inhibition of NUP205 in Mammary Epithelial Cell Line causally result in cell proliferation? | 1 | 2,248 | Inhibition | NUP205 | cell proliferation | Mammary Epithelial Cell Line | Gene: NUP205 (nucleoporin 205)
Type: protein-coding
Summary: This gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with ... |
Does Knockout of CCT4 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 815 | Knockout | CCT4 | cell proliferation | Colonic Cancer Cell Line | Gene: CCT4 (chaperonin containing TCP1 subunit 4)
Type: protein-coding
Summary: The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly... |
Does Knockout of MRPL44 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | MRPL44 | cell proliferation | Glioblastoma Cell Line | Gene: MRPL44 (mitochondrial ribosomal protein L44)
Type: protein-coding
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.... |
Does Knockout of NEURL1B in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | NEURL1B | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: NEURL1B (neuralized E3 ubiquitin protein ligase 1B)
Type: protein-coding
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent endocytosis. Located in actin cytoskeleton and cytosol. [provided by Alliance of Genome Resources, Apr 2022]
... |
Does Knockout of CDC123 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | CDC123 | cell proliferation | Glioblastoma Cell Line | Gene: CDC123 (cell division cycle 123)
Type: protein-coding
Summary: Predicted to be involved in eukaryotic translation initiation factor 2 complex assembly and positive regulation of translational initiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontol... |
Does Knockout of OTOP2 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 865 | Knockout | OTOP2 | cell proliferation | Colonic Cancer Cell Line | Gene: OTOP2 (otopetrin 2)
Type: protein-coding
Summary: Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022... |
Does Knockout of ACSL6 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | ACSL6 | cell proliferation | Gastric Cancer Cell Line | Gene: ACSL6 (acyl-CoA synthetase long chain family member 6)
Type: protein-coding
Summary: The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Tra... |
Does Knockout of COX20 in Colorectal Cancer Cell Line causally result in cell proliferation? | 1 | 783 | Knockout | COX20 | cell proliferation | Colorectal Cancer Cell Line | Gene: COX20 (cytochrome c oxidase assembly factor COX20)
Type: protein-coding
Summary: This gene encodes a protein that plays a role in the assembly of cytochrome C oxidase, an important component of the respiratory pathway. It contains two transmembrane helices and localizes to the mitochondrial membra... |
Does Knockout of RPL31 in Primary Effusion Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,061 | Knockout | RPL31 | response to chemicals | Primary Effusion Lymphoma Cell Line | Gene: RPL31 (ribosomal protein L31)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
Does Knockout of PIANP in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,119 | Knockout | PIANP | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: PIANP (PILR alpha associated neural protein)
Type: protein-coding
Summary: This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins. [provid... |
Does Knockout of SAAL1 in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | SAAL1 | cell proliferation | T-lymphoma cell line | Gene: SAAL1 (serum amyloid A like 1)
Type: protein-coding
Summary: Acts upstream of or within positive regulation of synoviocyte proliferation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: positive regulation of synoviocyte proliferation; CC: n... |
Does Knockout of NDUFAB1 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | NDUFAB1 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1)
Type: protein-coding
Summary: Predicted to enable acyl binding activity; acyl carrier activity; and fatty acid binding activity. Involved in mitochondrial respiratory chain complex I assembly and protein lipoylation. Located in mitochondrion and... |
Does Knockout of CTRB1 in Primary Effusion Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,061 | Knockout | CTRB1 | response to chemicals | Primary Effusion Lymphoma Cell Line | Gene: CTRB1 (chymotrypsinogen B1)
Type: protein-coding
Summary: This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the sm... |
Does Knockout of MIR4743 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,447 | Knockout | MIR4743 | response to virus | Hepatoma Cell Line | Gene: MIR4743 (microRNA 4743)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase... |
Does Knockout of NCBP2 in acute lymphoblastic leukemia cell line causally result in cell proliferation? | 1 | 1,957 | Knockout | NCBP2 | cell proliferation | acute lymphoblastic leukemia cell line | Gene: NCBP2 (nuclear cap binding protein subunit 2)
Type: protein-coding
Summary: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly foun... |
Does Knockout of SNRPD1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | SNRPD1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide)
Type: protein-coding
Summary: This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interaction... |
Does Knockout of RAB11FIP4 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 815 | Knockout | RAB11FIP4 | cell proliferation | Colonic Cancer Cell Line | Gene: RAB11FIP4 (RAB11 family interacting protein 4)
Type: protein-coding
Summary: The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of th... |
Does Knockout of PRAC1 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 951 | Knockout | PRAC1 | cell proliferation | Colonic Cancer Cell Line | Gene: PRAC1 (PRAC1 small nuclear protein)
Type: protein-coding
Summary: This gene is reported to be specifically expressed in prostate, rectum and distal colon. Sequence analysis suggests that it may play a regulatory role in the nucleus. [provided by RefSeq, Jul 2008].
Gene Ontology: CC: cytos... |
Does Knockout of TPI1 in Cancer Cell Line causally result in cell proliferation? | 1 | 1,308 | Knockout | TPI1 | cell proliferation | Cancer Cell Line | Gene: TPI1 (triosephosphate isomerase 1)
Type: protein-coding
Summary: This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gen... |
Does Knockout of KIAA1671 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 334 | Knockout | KIAA1671 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: KIAA1671 (KIAA1671)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cilium, intercellular bridge, microtubule cytoskeleton
Pathways:
UniProt: Q9BY89
Entrez ID: 85379 |
Does Knockout of P2RX6 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,119 | Knockout | P2RX6 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: P2RX6 (purinergic receptor P2X 6)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated ... |
Does Knockout of RFFL in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | RFFL | cell proliferation | Cancer Cell Line | Gene: RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase)
Type: protein-coding
Summary: Enables enzyme binding activity; p53 binding activity; and ubiquitin protein ligase activity. Involved in cellular protein metabolic process; negative regulation of cysteine-type endopeptid... |
Does Knockout of CHCHD6 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | CHCHD6 | response to virus | Hepatoma Cell Line | Gene: CHCHD6 (coiled-coil-helix-coiled-coil-helix domain containing 6)
Type: protein-coding
Summary: Involved in cellular response to DNA damage stimulus and cristae formation. Located in cytosol and mitochondrial inner membrane. Part of MICOS complex. [provided by Alliance of Genome Resources, Apr 2022... |
Does Knockout of P3H3 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,396 | Knockout | P3H3 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: P3H3 (prolyl 3-hydroxylase 3)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family mem... |
Does Knockout of COQ2 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 1 | 2,119 | Knockout | COQ2 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: COQ2 (coenzyme Q2, polyprenyltransferase)
Type: protein-coding
Summary: This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the c... |
Does Knockout of EIF4E in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | EIF4E | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: EIF4E (eukaryotic translation initiation factor 4E)
Type: protein-coding
Summary: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein ai... |
Does Knockout of BAD in Large Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 734 | Knockout | BAD | cell proliferation | Large Cell Lung Cancer Cell Line | Gene: BAD (BCL2 associated agonist of cell death)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL... |
Does Knockout of FAM110A in Cervical Adenocarcinoma Cell Line causally result in response to virus? | 0 | 2,033 | Knockout | FAM110A | response to virus | Cervical Adenocarcinoma Cell Line | Gene: FAM110A (family with sequence similarity 110 member A)
Type: protein-coding
Summary: Predicted to be located in cytoplasm; microtubule organizing center; and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: cell cortex, centrosome, cytoplasm, cytoskele... |
Does Knockout of ANAPC4 in Glioblastoma Cell Line causally result in cell proliferation? | 1 | 519 | Knockout | ANAPC4 | cell proliferation | Glioblastoma Cell Line | Gene: ANAPC4 (anaphase promoting complex subunit 4)
Type: protein-coding
Summary: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which... |
Does Knockout of TSEN15 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | TSEN15 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: TSEN15 (tRNA splicing endonuclease subunit 15)
Type: protein-coding
Summary: This gene encodes a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from tRNA precursors. Alternative splicing results in multiple transcript variants. There is a pseudogene of this gene ... |
Does Knockout of CWC25 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | CWC25 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: CWC25 (CWC25 spliceosome associated protein)
Type: protein-coding
Summary: This gene encodes a factor that is part of the multi-protein C complex involved in pre-mRNA splicing. Alternatively spliced transcripts have been described for this gene. [provided by RefSeq, Nov 2012].
Gene Ontolo... |
Does Knockout of KRTAP10-2 in Non-Small Cell Lung Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 1,391 | Knockout | KRTAP10-2 | response to chemicals | Non-Small Cell Lung Adenocarcinoma Cell Line | Gene: KRTAP10-2 (keratin associated protein 10-2)
Type: protein-coding
Summary: This gene encodes a member of the high sulfur-type keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. This gene is loca... |
Does Knockout of ELMOD2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | ELMOD2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: ELMOD2 (ELMO domain containing 2)
Type: protein-coding
Summary: This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary f... |
Does Knockout of SUPV3L1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | SUPV3L1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SUPV3L1 (Suv3 like RNA helicase)
Type: protein-coding
Summary: Enables helicase activity; nucleic acid binding activity; and protein homodimerization activity. Involved in several processes, including mitochondrial RNA metabolic process; mitochondrion morphogenesis; and positive regulation of mito... |
Does Knockout of NXPE1 in Colonic Adenocarcinoma Cell Line causally result in response to bacteria? | 0 | 1,480 | Knockout | NXPE1 | response to bacteria | Colonic Adenocarcinoma Cell Line | Gene: NXPE1 (neurexophilin and PC-esterase domain family member 1)
Type: protein-coding
Summary: Predicted to be located in extracellular region. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
Uni... |
Does Knockout of LONP1 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 408 | Knockout | LONP1 | cell proliferation | Medulloblastoma Cell Line | Gene: LONP1 (lon peptidase 1, mitochondrial)
Type: protein-coding
Summary: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mito... |
Does Knockout of LAS1L in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | LAS1L | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: LAS1L (LAS1 like ribosome biogenesis factor)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Located in membrane. Part of MLL1 complex. Implicated in Wilson-Turner syndrome. [provided by Alliance of Genome ... |
Does Knockout of MCM3 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 334 | Knockout | MCM3 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: MCM3 (minichromosome maintenance complex component 3)
Type: protein-coding
Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed ... |
Does Knockout of SFRP2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | SFRP2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: SFRP2 (secreted frizzled related protein 2)
Type: protein-coding
Summary: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene ... |
Does Knockout of MIEF1 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | MIEF1 | response to virus | Hepatoma Cell Line | Gene: MIEF1 (mitochondrial elongation factor 1)
Type: protein-coding
Summary: Enables ADP binding activity; GDP binding activity; and identical protein binding activity. Involved in several processes, including positive regulation of mitochondrial fission; positive regulation of mitochondrial translatio... |
Does Knockout of FAM217B in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | FAM217B | cell proliferation | Monocytic Leukemia Cell Line | Gene: FAM217B (family with sequence similarity 217 member B)
Type: protein-coding
Summary: Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: cytosol, nucleoplasm
Pathways:
UniProt: Q9NTX9
Entrez ID: 63939 |
Does Knockout of PAOX in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | PAOX | cell proliferation | Mammary Gland Tumor Cell Line | Gene: PAOX (polyamine oxidase)
Type: protein-coding
Summary: Enables polyamine oxidase activity. Involved in polyamine metabolic process and positive regulation of spermidine biosynthetic process. Predicted to be located in cytosol and peroxisomal matrix. [provided by Alliance of Genome Resources, Apr 2... |
Does Knockout of C11orf40 in Prostate Cancer Cell Line causally result in cell proliferation? | 0 | 843 | Knockout | C11orf40 | cell proliferation | Prostate Cancer Cell Line | Gene: C11orf40 (chromosome 11 putative open reading frame 40)
Type: ncRNA
Summary: chromosome 11 putative open reading frame 40
Gene Ontology:
Pathways:
UniProt:
Entrez ID: 143501 |
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